| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Methanococcus maripaludis S2 | MMP_RS05265 | | 2-isopropylmalate synthase | strong | 100 | 100 |
| o | Methanococcus maripaludis JJ | MMJJ_RS09115 | | 2-isopropylmalate synthase | no data | 100 | 100 |
| | Methanococcus maripaludis S2 | MMP_RS05500 | | 2-isopropylmalate synthase | strong | 49 | 100 |
| | Methanococcus maripaludis JJ | MMJJ_RS08870 | | 2-isopropylmalate synthase | insig. | 49 | 100 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU2981 | leuA | 2-isopropylmalate synthase (TIGR) | strong | 41 | 100 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1791 | | 2-isopropylmalate synthase (RefSeq) | strong | 40 | 100 |
| | Xanthobacter sp. DMC5 | GFF2400 | | 2-isopropylmalate synthase | strong | 40 | 99 |
| | Pseudomonas stutzeri RCH2 | Psest_1056 | | 2-isopropylmalate synthase, bacterial type | insig. | 40 | 99 |
| | Methanococcus maripaludis S2 | MMP_RS00870 | | homocitrate synthase family protein | no data | 47 | 74 |
| | Methanococcus maripaludis JJ | MMJJ_RS04620 | | homocitrate synthase family protein | sig. | 47 | 74 |
| | Marinobacter adhaerens HP15 | HP15_538 | | 2-isopropylmalate synthase | insig. | 40 | 99 |
| | Bosea sp. OAE506 | ABIE41_RS13000 | | 2-isopropylmalate synthase | insig. | 40 | 99 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS17765 | | 2-isopropylmalate synthase | insig. | 40 | 99 |
| | Rhodopseudomonas palustris CGA009 | TX73_010545 | | 2-isopropylmalate synthase | sig. | 38 | 99 |
| | Dechlorosoma suillum PS | Dsui_3519 | | 2-isopropylmalate synthase, bacterial type | insig. | 39 | 99 |
| | Methylophilus sp. DMC18 | GFF1746 | | 2-isopropylmalate synthase | cofit | 40 | 99 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_04604 | | 2-isopropylmalate synthase | strong | 39 | 99 |
| | Dinoroseobacter shibae DFL-12 | Dshi_0596 | | 2-isopropylmalate synthase (RefSeq) | cofit | 38 | 99 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS14545 | | 2-isopropylmalate synthase | strong | 39 | 99 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS16665 | | 2-isopropylmalate synthase | strong | 38 | 99 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT1861 | | 2-isopropylmalate synthase (EC 2.3.3.13) (from data) | strong | 39 | 99 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS10195 | | 2-isopropylmalate synthase | strong | 39 | 99 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS14150 | | 2-isopropylmalate synthase | strong | 39 | 99 |
| | Rahnella sp. WP5 | EX31_RS03680 | | 2-isopropylmalate synthase | strong | 36 | 99 |
| | Caulobacter crescentus NA1000 | CCNA_01610 | | 2-isopropylmalate synthase | strong | 38 | 100 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_01610 | | 2-isopropylmalate synthase | cofit | 38 | 100 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_1410 | leuA | 2-isopropylmalate synthase | no data | 39 | 99 |
| | Alteromonas macleodii MIT1002 | MIT1002_00949 | | 2-isopropylmalate synthase | strong | 37 | 99 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.1056.1 | | 2-isopropylmalate synthase (EC 2.3.3.13) | cofit | 37 | 100 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c26470 | | 2-isopropylmalate synthase LeuA | strong | 39 | 99 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS09985 | | 2-isopropylmalate synthase | cofit | 38 | 92 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS10345 | | 2-isopropylmalate synthase | strong | 38 | 92 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_13575 | leuA | 2-isopropylmalate synthase | strong | 38 | 92 |
| | Paraburkholderia graminis OAS925 | ABIE53_001580 | | 2-isopropylmalate synthase | insig. | 37 | 99 |
| | Lysobacter sp. OAE881 | ABIE51_RS17570 | | 2-isopropylmalate synthase | strong | 37 | 100 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS24195 | | 2-isopropylmalate synthase | insig. | 39 | 99 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS03120 | | 2-isopropylmalate synthase | strong | 38 | 92 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_04556 | | 2-isopropylmalate synthase | insig. | 37 | 99 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS15970 | | 2-isopropylmalate synthase | strong | 36 | 100 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS12850 | | 2-isopropylmalate synthase | no data | 39 | 99 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_530 | | 2-isopropylmalate synthase (EC 2.3.3.13) | sig. | 38 | 99 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS06570 | | 2-isopropylmalate synthase | insig. | 37 | 99 |
| | Serratia liquefaciens MT49 | IAI46_03355 | | 2-isopropylmalate synthase | insig. | 36 | 99 |
| | Shewanella amazonensis SB2B | Sama_0335 | | 2-isopropylmalate synthase (RefSeq) | strong | 34 | 99 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS05465 | | 2-isopropylmalate synthase | strong | 38 | 99 |
| | Dickeya dadantii 3937 | DDA3937_RS18115 | | 2-isopropylmalate synthase | strong | 35 | 99 |
| | Shewanella loihica PV-4 | Shew_3472 | | 2-isopropylmalate synthase (RefSeq) | strong | 35 | 99 |
| | Azospirillum brasilense Sp245 | AZOBR_RS05495 | | homocitrate synthase | strong | 42 | 71 |
| | Shewanella sp. ANA-3 | Shewana3_3761 | | 2-isopropylmalate synthase (RefSeq) | strong | 36 | 99 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS03025 | | 2-isopropylmalate synthase | insig. | 39 | 99 |
| | Ralstonia solanacearum GMI1000 | RS_RS10395 | | 2-isopropylmalate synthase | strong | 39 | 99 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS14285 | | 2-isopropylmalate synthase | insig. | 39 | 99 |
| | Ralstonia solanacearum UW163 | UW163_RS10700 | | 2-isopropylmalate synthase | insig. | 39 | 99 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS14210 | | homocitrate synthase | strong | 42 | 70 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS14930 | | 2-isopropylmalate synthase | insig. | 38 | 99 |
| | Shewanella oneidensis MR-1 | SO4236 | leuA | 2-isopropylmalate synthase (NCBI ptt file) | strong | 36 | 99 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13516_RS16310 | leuA | 2-isopropylmalate synthase | strong | 34 | 99 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_2234 | | 2-isopropylmalate synthase (EC 2.3.3.13) | sig. | 42 | 74 |
| | Azospirillum sp. SherDot2 | MPMX19_00469 | | 2-phosphonomethylmalate synthase | insig. | 41 | 72 |
| | Dickeya dianthicola ME23 | DZA65_RS19200 | | 2-isopropylmalate synthase | strong | 35 | 99 |
| | Pectobacterium carotovorum WPP14 | HER17_RS03085 | | 2-isopropylmalate synthase | strong | 35 | 99 |
| | Dickeya dianthicola 67-19 | HGI48_RS18055 | | 2-isopropylmalate synthase | strong | 35 | 99 |
| | Pantoea sp. MT58 | IAI47_16000 | | 2-isopropylmalate synthase | strong | 34 | 99 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF4281 | | 2-isopropylmalate synthase (EC 2.3.3.13) | insig. | 37 | 99 |
| | Erwinia amylovora T8 | OLJFJH_01285 | | 2-isopropylmalate synthase | strong | 34 | 99 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_3670 | | 2-isopropylmalate synthase (EC 2.3.3.13) | strong | 35 | 99 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_12595 | | 2-isopropylmalate synthase | cofit | 36 | 99 |
| | Escherichia coli BL21 | ECD_00076 | | 2-isopropylmalate synthase | strong | 35 | 99 |
| | Escherichia coli ECRC100 | OKFHMN_10715 | | 2-isopropylmalate synthase | strong | 35 | 99 |
| | Escherichia coli ECRC101 | MCAODC_01230 | | 2-isopropylmalate synthase | strong | 35 | 99 |
| | Escherichia coli ECRC102 | NIAGMN_08565 | | 2-isopropylmalate synthase | strong | 35 | 99 |
| | Escherichia coli ECRC98 | JDDGAC_14310 | | 2-isopropylmalate synthase | strong | 35 | 99 |
| | Escherichia coli ECRC99 | KEDOAH_17440 | | 2-isopropylmalate synthase | no data | 35 | 99 |
| | Escherichia coli BW25113 | b0074 | leuA | 2-isopropylmalate synthase (NCBI) | strong | 35 | 99 |
| | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_05995 | leuA | 2-isopropylmalate synthase | strong | 34 | 99 |
| | Erwinia tracheiphila SCR3 | LU632_RS02880 | leuA | 2-isopropylmalate synthase | strong | 34 | 99 |
| | Escherichia fergusonii Becca | EFB2_03971 | | 2-isopropylmalate synthase | insig. | 35 | 99 |
| | Escherichia coli ECOR27 | NOLOHH_03060 | | 2-isopropylmalate synthase | strong | 35 | 99 |
| | Escherichia coli ECOR38 | HEPCGN_08695 | | 2-isopropylmalate synthase | strong | 35 | 99 |
| | Escherichia coli ECRC62 | BNILDI_08550 | | 2-isopropylmalate synthase | strong | 35 | 99 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_03583 | | 2-isopropylmalate synthase | insig. | 35 | 99 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS00400 | | 2-isopropylmalate synthase | strong | 35 | 99 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS42240 | | homocitrate synthase | cofit | 39 | 75 |
| | Variovorax sp. OAS795 | ABID97_RS14910 | | 2-isopropylmalate synthase | insig. | 36 | 99 |
| | Variovorax sp. SCN45 | GFF1165 | | 2-isopropylmalate synthase (EC 2.3.3.13) | cofit | 36 | 99 |
| | Klebsiella michiganensis M5al | BWI76_RS04680 | | 2-isopropylmalate synthase | strong | 35 | 99 |
| | Enterobacter sp. TBS_079 | MPMX20_00769 | | 2-isopropylmalate synthase | strong | 35 | 99 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_12910 | | 2-isopropylmalate synthase | insig. | 35 | 99 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS11610 | | 2-isopropylmalate synthase | cofit | 41 | 74 |
| | Klebsiella pneumoniae MRSN742743 | KFA93_RS11375 | leuA;go_function=2-isopropylmalate | 2-isopropylmalate synthase | insig. | 34 | 99 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_09430 | | 2-isopropylmalate synthase | sig. | 40 | 74 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS15855 | | 2-isopropylmalate synthase (EC 2.3.3.13) (from data) | strong | 40 | 74 |
| | Rhodopseudomonas palustris CGA009 | TX73_023930 | | homocitrate synthase | strong | 38 | 70 |
| | Methylophilus sp. DMC18 | GFF117 | | 2-phosphonomethylmalate synthase | insig. | 38 | 71 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS07875 | | homocitrate synthase | insig. | 41 | 64 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS10010 | | 2-isopropylmalate synthase | strong | 39 | 75 |
| | Rhodospirillum rubrum S1H | Rru_A2269 | | Pyruvate carboxyltransferase (NCBI) | strong | 36 | 75 |
| | Cellulophaga baltica 18 | M666_RS13580 | | 2-isopropylmalate synthase | insig. | 39 | 74 |
| | Dechlorosoma suillum PS | Dsui_0578 | | homocitrate synthase NifV | strong | 38 | 71 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_3833 | | 2-isopropylmalate synthase (EC 2.3.3.13) (from data) | strong | 40 | 73 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_04601 | | LeuA allosteric (dimerization) domain protein | strong | 33 | 100 |
| | Xanthobacter sp. DMC5 | GFF4414 | | 2-phosphonomethylmalate synthase | insig. | 37 | 71 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT1858 | | (R)-citramalate synthase (EC 2.3.1.182) (from data) | strong | 34 | 99 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS14560 | | 2-isopropylmalate synthase | strong | 33 | 100 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS10210 | | 2-isopropylmalate synthase | strong | 33 | 100 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2061 | | Isopropylmalate/homocitrate/citramalate synthases | strong | 33 | 99 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS16650 | | alpha-isopropylmalate synthase regulatory domain-containing protein | strong | 31 | 99 |
| | Dickeya dianthicola 67-19 | HGI48_RS18850 | | homocitrate synthase | insig. | 34 | 75 |
| | Klebsiella michiganensis M5al | BWI76_RS18860 | | homocitrate synthase | strong | 33 | 75 |
| | Dickeya dadantii 3937 | DDA3937_RS18845 | | homocitrate synthase | sig. | 34 | 75 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS14135 | | 2-isopropylmalate synthase | strong | 32 | 100 |
| | Dickeya dianthicola ME23 | DZA65_RS19960 | | homocitrate synthase | insig. | 34 | 75 |
| | Cellulophaga baltica 18 | M666_RS15050 | | alpha-isopropylmalate synthase regulatory domain-containing protein | insig. | 32 | 100 |
| | Rahnella sp. WP5 | EX31_RS15370 | | homocitrate synthase | insig. | 36 | 71 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS11140 | | citramalate synthase | insig. | 30 | 99 |
| | Sinorhizobium meliloti 1021 | SMc02546 | | alpha-isopropylmalate/homocitrate synthase family transferase | insig. | 30 | 99 |
| | Methylophilus sp. DMC18 | GFF644 | | (R)-citramalate synthase | cofit | 29 | 98 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_0428 | leuA | putative alpha-isopropylmalate/homocitrate synthase family transferase | strong | 29 | 99 |
| | Bosea sp. OAE506 | ABIE41_RS20855 | | citramalate synthase | insig. | 31 | 99 |
| | Azospirillum sp. SherDot2 | MPMX19_02019 | | (R)-citramalate synthase | insig. | 29 | 99 |
| | Rhizobium sp. OAE497 | ABIE40_RS06220 | | citramalate synthase | strong | 29 | 99 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_0275 | | putative alpha-isopropylmalate/homocitrate synthase family transferase (RefSeq) | strong | 27 | 99 |
| | Dinoroseobacter shibae DFL-12 | Dshi_1696 | | 2-isopropylmalate synthase/homocitrate synthase family protein (RefSeq) | sig. | 29 | 99 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF163 | | 2-isopropylmalate synthase (EC 2.3.3.13) | insig. | 36 | 52 |
| | Xanthobacter sp. DMC5 | GFF267 | | (R)-citramalate synthase | strong | 29 | 99 |
| | Azospirillum brasilense Sp245 | AZOBR_RS04265 | | 2-isopropylmalate synthase | strong | 28 | 99 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU1914 | | (R)-citramalate synthase (EC 2.3.3.21) (from data) | strong | 26 | 99 |
| | Rhodopseudomonas palustris CGA009 | TX73_010310 | | citramalate synthase | no data | 29 | 99 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_24260 | | hypothetical protein | insig. | 32 | 61 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS06330 | | 2-isopropylmalate synthase | insig. | 30 | 70 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS46465 | | 2-isopropylmalate synthase | insig. | 30 | 70 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_05725 | | 2-isopropylmalate synthase | sig. | 30 | 70 |
| | Rhodospirillum rubrum S1H | Rru_A0695 | | 2-isopropylmalate synthase/homocitrate synthase (NCBI) | sig. | 27 | 99 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c16460 | | 2-isopropylmalate synthase/homocitrate synthase-like protein | sig. | 28 | 99 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS10755 | | citramalate synthase | no data | 28 | 100 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2612 | | pyruvate carboxyltransferase (RefSeq) | sig. | 31 | 64 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVUA0016 | nifV | homocitrate synthase (TIGR) | strong | 30 | 73 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0398 | | HMGL-like domain protein (TIGR) | cofit | 27 | 82 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1549 | | pyruvate carboxyltransferase (RefSeq) | strong | 26 | 84 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF164 | | 2-isopropylmalate synthase (EC 2.3.3.13) | insig. | 35 | 46 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF4280 | | 2-isopropylmalate synthase (EC 2.3.3.13) | sig. | 25 | 98 |
| | Castellaniella sp019104865 MT123 | ABCV34_RS12420 | | 2-isopropylmalate synthase | strong | 23 | 98 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS17185 | | 2-isopropylmalate synthase | strong | 27 | 74 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_00385 | | 2-isopropylmalate synthase | strong | 27 | 75 |
| | Serratia liquefaciens MT49 | IAI46_16105 | | 4-hydroxy-2-oxovalerate aldolase | insig. | 27 | 54 |
| | Methylophilus sp. DMC18 | GFF446 | | 2-isopropylmalate synthase | insig. | 25 | 74 |
| | Azospirillum sp. SherDot2 | MPMX19_01822 | | 2-isopropylmalate synthase | strong | 24 | 64 |
| | Variovorax sp. OAS795 | ABID97_RS14905 | | 2-isopropylmalate synthase | strong | 27 | 74 |
| | Variovorax sp. SCN45 | GFF1164 | | 2-isopropylmalate synthase (EC 2.3.3.13) | strong | 27 | 74 |
| | Fusobacterium nucleatum SB010 | HUW76_08595 | | oxaloacetate decarboxylase subunit alpha | strong | 27 | 53 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS21205 | | 2-isopropylmalate synthase | insig. | 22 | 98 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_03571 | | hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) | insig. | 26 | 55 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_02262 | | Hydroxymethylglutaryl-CoA lyase YngG | cofit | 26 | 58 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS13280 | | 2-isopropylmalate synthase | strong | 24 | 98 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS01320 | | 2-isopropylmalate synthase | insig. | 27 | 59 |
| | Marinobacter adhaerens HP15 | HP15_2055 | | 2-isopropylmalate synthase | sig. | 24 | 98 |
| | Methylophilus sp. DMC18 | GFF1260 | | Oxaloacetate decarboxylase alpha chain | no data | 26 | 54 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS12170 | | hydroxymethylglutaryl-CoA lyase | insig. | 28 | 54 |
| | Pseudomonas sp. S08-1 | OH686_17570 | | 2-isopropylmalate synthase | strong | 22 | 67 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS21840 | | 2-isopropylmalate synthase | insig. | 27 | 59 |
| | Ralstonia solanacearum UW163 | UW163_RS17345 | | 2-isopropylmalate synthase | insig. | 27 | 59 |
| | Paraburkholderia graminis OAS925 | ABIE53_004685 | | hydroxymethylglutaryl-CoA lyase | insig. | 27 | 55 |
| | Azospirillum brasilense Sp245 | AZOBR_RS12155 | | 2-isopropylmalate synthase | strong | 24 | 98 |
| | Dechlorosoma suillum PS | Dsui_3227 | | 2-isopropylmalate synthase | sig. | 23 | 98 |
| | Paraburkholderia graminis OAS925 | ABIE53_002867 | | 2-isopropylmalate synthase | strong | 24 | 66 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS17550 | | 2-isopropylmalate synthase | strong | 23 | 98 |
| | Agrobacterium fabrum C58 | Atu2264 | | 2-isopropylmalate synthase | strong | 25 | 67 |
| | Acinetobacter baumannii LAC-4 | RR41_RS16605 | | 2-isopropylmalate synthase | insig. | 22 | 99 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS22365 | | 2-isopropylmalate synthase | insig. | 26 | 67 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_06550 | | 2-isopropylmalate synthase | strong | 24 | 73 |
| | Ralstonia solanacearum GMI1000 | RS_RS18695 | | 2-isopropylmalate synthase 2 | insig. | 32 | 33 |
| | Rhodospirillum rubrum S1H | Rru_A1928 | | Yeast 2-isopropylmalate synthase (NCBI) | strong | 22 | 90 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_4547 | | Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) | insig. | 27 | 55 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_04100 | | oxaloacetate decarboxylase subunit alpha | insig. | 26 | 52 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS13255 | | hydroxymethylglutaryl-CoA lyase | sig. | 26 | 51 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS01640 | | 2-isopropylmalate synthase | insig. | 25 | 65 |
| | Pseudomonas segetis P6 | ACVTMO_RS07560 | leuA | 2-isopropylmalate synthase | strong | 24 | 66 |
| | Pseudomonas sp. DMC3 | GFF2240 | | Hydroxymethylglutaryl-CoA lyase YngG | cofit | 27 | 55 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_3170 | | 2-isopropylmalate synthase (EC 2.3.3.13) | strong | 24 | 73 |
| | Pseudomonas sp. RS175 | PFR28_00305 | | 2-isopropylmalate synthase | strong | 24 | 76 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_02770 | | 2-isopropylmalate synthase | insig. | 24 | 66 |
| | Pseudomonas sp. BP01 | JOY50_RS05265 | | hydroxymethylglutaryl-CoA lyase | no data | 26 | 49 |
| | Pseudomonas sp. RS175 | PFR28_02017 | | 4-hydroxy-2-oxovalerate aldolase | insig. | 25 | 51 |
| | Klebsiella pneumoniae MRSN742743 | KFA93_RS19015 | leuA;go_function=2-isopropylmalate | 2-isopropylmalate synthase | insig. | 24 | 66 |
| | Pseudomonas stutzeri RCH2 | Psest_2980 | | oxaloacetate decarboxylase alpha subunit | strong | 29 | 32 |
| | Acinetobacter radioresistens SK82 | MPMX26_00404 | | 2-isopropylmalate synthase | strong | 25 | 67 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS34520 | | hydroxymethylglutaryl-CoA lyase | insig. | 26 | 55 |
| | Marinobacter adhaerens HP15 | HP15_1331 | | pyruvate carboxylase subunit B | strong | 32 | 32 |
| | Pseudomonas segetis P6 | ACVTMO_RS00850 | oadA | sodium-extruding oxaloacetate decarboxylase subunit alpha | strong | 32 | 29 |
| | Pseudomonas protegens RBAN4 | FABNJH_31060 | oadA | sodium-extruding oxaloacetate decarboxylase subunit alpha | strong | 32 | 30 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_1257 | | 2-isopropylmalate synthase | strong | 30 | 33 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1257 | | 2-isopropylmalate synthase | strong | 30 | 33 |
| | Mycobacterium tuberculosis H37Rv | Rv3710 | | 2-isopropylmalate synthase LeuA (alpha-isopropylmalate synthase) (alpha-IPM synthetase) (IPMS) | no data | 25 | 90 |
| | Pseudomonas stutzeri RCH2 | Psest_4084 | | oxaloacetate decarboxylase alpha subunit | strong | 32 | 29 |
| | Castellaniella sp019104865 MT123 | ABCV34_RS08850 | | hydroxymethylglutaryl-CoA lyase | insig. | 26 | 49 |
| | Methanococcus maripaludis JJ | MMJJ_RS03560 | | sodium-extruding oxaloacetate decarboxylase subunit alpha | no data | 24 | 49 |
| | Methanococcus maripaludis S2 | MMP_RS01820 | | sodium-extruding oxaloacetate decarboxylase subunit alpha | no data | 24 | 49 |
| | Pseudomonas segetis P6 | ACVTMO_RS15805 | oadA | sodium-extruding oxaloacetate decarboxylase subunit alpha | insig. | 28 | 32 |
| | Shewanella amazonensis SB2B | Sama_1358 | | pyruvate carboxyltransferase (RefSeq) | strong | 27 | 51 |
| | Pseudomonas orientalis W4I3 | QF045_RS09680 | | hydroxymethylglutaryl-CoA lyase | insig. | 25 | 58 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_4031 | | 2-isopropylmalate synthase, yeast type | strong | 24 | 63 |
| | Enterobacter sp. TBS_079 | MPMX20_03565 | | 2-isopropylmalate synthase | insig. | 26 | 66 |
| | Pseudomonas sp. BP01 | JOY50_RS11470 | leuA | 2-isopropylmalate synthase | strong | 29 | 33 |
| | Mycobacterium tuberculosis H37Rv | Rv3469c | | Probable 4-hydroxy-2-oxovalerate aldolase MhpE (HOA) | insig. | 24 | 59 |
| | Pseudomonas protegens RBAN4 | FABNJH_21290 | leuA | 2-isopropylmalate synthase | insig. | 24 | 65 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_370 | | Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) | insig. | 24 | 57 |
| | Rhodopseudomonas palustris CGA009 | TX73_024250 | | 2-isopropylmalate synthase | insig. | 24 | 61 |
| | Acinetobacter radioresistens SK82 | MPMX26_03077 | | 2-isopropylmalate synthase | no data | 25 | 49 |
| | Pseudomonas putida KT2440 | PP_1025 | | 2-isopropylmalate synthase | strong | 28 | 33 |
| | Serratia liquefaciens MT49 | IAI46_09630 | | 2-isopropylmalate synthase | insig. | 25 | 44 |
| | Agrobacterium fabrum C58 | Atu3480 | | hydroxymethylglutaryl-CoA lyase | sig. | 26 | 55 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_02945 | | oxaloacetate decarboxylase subunit alpha | insig. | 29 | 26 |
| | Pseudomonas orientalis W4I3 | QF045_RS24560 | | 2-isopropylmalate synthase | strong | 23 | 61 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_2770 | | 2-isopropylmalate synthase, yeast type | insig. | 26 | 42 |
| | Sinorhizobium meliloti 1021 | SMc02717 | | 2-isopropylmalate synthase | strong | 25 | 68 |
| | Pseudomonas segetis P6 | ACVTMO_RS22160 | | 2-isopropylmalate synthase | insig. | 24 | 66 |
| | Pseudomonas sp. BP01 | JOY50_RS08770 | oadA | sodium-extruding oxaloacetate decarboxylase subunit alpha | strong | 31 | 29 |
| | Klebsiella michiganensis M5al | BWI76_RS22105 | | 2-isopropylmalate synthase | insig. | 25 | 66 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS23475 | | hydroxymethylglutaryl-CoA lyase | strong | 24 | 53 |
| | Pseudomonas stutzeri RCH2 | Psest_1277 | | 2-isopropylmalate synthase, yeast type | strong | 22 | 61 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1040 | | Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) | insig. | 26 | 49 |
| | Pseudomonas sp. S08-1 | OH686_13205 | | oxaloacetate decarboxylase alpha subunit | strong | 31 | 29 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_12025 | | pyruvate carboxylase subunit B | strong | 31 | 29 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_4279 | | Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) | strong | 31 | 29 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_15925 | | 2-isopropylmalate synthase | strong | 27 | 42 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS16990 | | hydroxymethylglutaryl-CoA lyase | insig. | 26 | 56 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_5060 | | Oxaloacetate decarboxylase, alpha subunit | strong | 31 | 29 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_5060 | | Oxaloacetate decarboxylase, alpha subunit | cofit | 31 | 29 |
| | Bifidobacterium breve UCC2003 | BBR_RS11170 | | 2-isopropylmalate synthase | strong | 24 | 65 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_00110 | | Oxaloacetate decarboxylase alpha chain | strong | 31 | 29 |
| | Pseudomonas orientalis W4I3 | QF045_RS02570 | | sodium-extruding oxaloacetate decarboxylase subunit alpha | strong | 31 | 29 |
| | Pseudomonas sp. RS175 | PFR28_04517 | | Oxaloacetate decarboxylase alpha chain | strong | 30 | 29 |
| | Pseudomonas sp. SVBP6 | COO64_RS04630 | leuA | 2-isopropylmalate synthase | strong | 28 | 33 |
| | Pseudomonas orientalis W4I3 | QF045_RS25330 | | 2-isopropylmalate synthase | insig. | 22 | 98 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF225 | | Oxaloacetate decarboxylase alpha chain (EC 4.1.1.3) | insig. | 30 | 30 |
| | Pseudomonas putida KT2440 | PP_5346 | | pyruvate carboxylase subunit B | strong | 30 | 29 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_2011 | | Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) | strong | 30 | 29 |
| | Pseudomonas simiae WCS417 | PS417_06935 | | hydroxymethylglutaryl-CoA lyase | insig. | 25 | 57 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS04700 | | 2-isopropylmalate synthase | insig. | 27 | 33 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_04774 | | 2-isopropylmalate synthase | strong | 22 | 98 |
| | Pseudomonas segetis P6 | ACVTMO_RS12005 | | hydroxymethylglutaryl-CoA lyase | insig. | 25 | 54 |
| | Pseudomonas sp. DMC3 | GFF4332 | | 2-isopropylmalate synthase | strong | 22 | 66 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_4854 | | 2-isopropylmalate synthase (EC 2.3.3.13) | strong | 22 | 98 |
| | Variovorax sp. OAS795 | ABID97_RS19460 | | hydroxymethylglutaryl-CoA lyase | insig. | 26 | 51 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02101 | | hydroxymethylglutaryl-CoA lyase | strong | 24 | 56 |
| | Pseudomonas simiae WCS417 | PS417_23110 | | 2-isopropylmalate synthase | strong | 23 | 98 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3018 | | Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) | no data | 26 | 53 |
| | Pseudomonas stutzeri RCH2 | Psest_2661 | | Isopropylmalate/homocitrate/citramalate synthases | insig. | 25 | 54 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS06990 | | hydroxymethylglutaryl-CoA lyase | insig. | 24 | 58 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS06990 | | hydroxymethylglutaryl-CoA lyase | strong | 24 | 58 |