| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Methanococcus maripaludis S2 | MMP_RS01180 | | XTP/dITP diphosphatase | sig. | 100 | 100 |
| o | Methanococcus maripaludis JJ | MMJJ_RS04195 | | XTP/dITP diphosphatase | strong | 99 | 99 |
| o | Phocaeicola dorei CL03T12C01 | ABI39_RS05750 | | non-canonical purine NTP diphosphatase | insig. | 39 | 98 |
| o | Bacteroides stercoris CC31F | HMPREF1181_RS01925 | | non-canonical purine NTP diphosphatase | insig. | 37 | 98 |
| o | Cellulophaga baltica 18 | M666_RS17985 | | non-canonical purine NTP diphosphatase | insig. | 40 | 98 |
| o | Pseudomonas stutzeri RCH2 | Psest_2799 | | Xanthosine triphosphate pyrophosphatase | insig. | 33 | 99 |
| o | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS11235 | | non-canonical purine NTP diphosphatase | strong | 38 | 98 |
| o | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS06565 | | non-canonical purine NTP diphosphatase | strong | 37 | 99 |
| o | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_19890 | | non-canonical purine NTP pyrophosphatase | insig. | 35 | 99 |
| o | Ralstonia solanacearum PSI07 | RPSI07_RS21980 | | non-canonical purine NTP pyrophosphatase | insig. | 31 | 98 |
| o | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS21980 | | non-canonical purine NTP diphosphatase | no data | 34 | 98 |
| o | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS24990 | | non-canonical purine NTP pyrophosphatase | insig. | 37 | 98 |
| o | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS08395 | | hypothetical protein | insig. | 33 | 99 |
| o | Pantoea sp. MT58 | IAI47_20055 | | non-canonical purine NTP pyrophosphatase | insig. | 33 | 99 |
| o | Bacteroides ovatus ATCC 8483 | BACOVA_02837 | | non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family | insig. | 34 | 99 |
| o | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_1180 | | non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family | strong | 37 | 98 |
| o | Bacteroides thetaiotaomicron VPI-5482 | BT3128 | | putative xanthosine triphosphate pyrophosphatase (NCBI ptt file) | insig. | 34 | 98 |
| o | Synechocystis sp000284455 PCC 6803 | SGL_RS12040 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | insig. | 36 | 99 |
| | Fusobacterium nucleatum SB010 | HUW76_01880 | | ribonuclease PH | strong | 35 | 100 |
| o | Xanthobacter sp. DMC5 | GFF1892 | | dITP/XTP pyrophosphatase | no data | 30 | 96 |
| o | Escherichia fergusonii Becca | EFB2_00948 | | dITP/XTP pyrophosphatase | sig. | 33 | 99 |
| o | Escherichia coli Nissle 1917 | ECOLIN_RS16430 | | XTP/dITP diphosphatase | cofit | 33 | 99 |
| o | Escherichia coli ECOR27 | NOLOHH_11110 | rdgB | XTP/dITP diphosphatase | insig. | 33 | 99 |
| o | Escherichia coli ECRC62 | BNILDI_09690 | rdgB | XTP/dITP diphosphatase | insig. | 33 | 99 |
| o | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_00762 | | dITP/XTP pyrophosphatase | strong | 33 | 99 |
| o | Escherichia coli ECOR38 | HEPCGN_18545 | rdgB | XTP/dITP diphosphatase | insig. | 33 | 99 |
| o | Escherichia coli ECRC100 | OKFHMN_19240 | rdgB | XTP/dITP diphosphatase | cofit | 33 | 99 |
| o | Escherichia coli ECRC102 | NIAGMN_17005 | rdgB | XTP/dITP diphosphatase | insig. | 33 | 99 |
| o | Escherichia coli ECRC98 | JDDGAC_22870 | rdgB | XTP/dITP diphosphatase | insig. | 33 | 99 |
| o | Escherichia coli ECRC99 | KEDOAH_08900 | rdgB | XTP/dITP diphosphatase | no data | 33 | 99 |
| o | Escherichia coli BL21 | ECD_02784 | | dITP/XTP pyrophosphatase | no data | 33 | 99 |
| o | Klebsiella michiganensis M5al | BWI76_RS24115 | | non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family | sig. | 33 | 99 |
| o | Escherichia coli ECRC101 | MCAODC_09760 | rdgB | XTP/dITP diphosphatase | strong | 32 | 99 |
| | Rhodospirillum rubrum S1H | Rru_A3640 | | Ham1-like protein (NCBI) | insig. | 35 | 64 |
| o | Escherichia coli BW25113 | b2954 | yggV | putative deoxyribonucleotide triphosphate pyrophosphatase (NCBI) | strong | 33 | 99 |
| o | Methylophilus sp. DMC18 | GFF2137 | | dITP/XTP pyrophosphatase | insig. | 27 | 99 |
| o | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3057 | | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) | cofit | 32 | 99 |
| o | Sphingomonas koreensis DSMZ 15582 | Ga0059261_2742 | | non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family | insig. | 26 | 96 |
| o | Synechococcus elongatus PCC 7942 | Synpcc7942_1266 | rdgB | Ham1-like protein | insig. | 30 | 99 |
| | Caulobacter crescentus NA1000 | CCNA_00145 | | xanthosine triphosphate pyrophosphatase | strong | 33 | 67 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_00145 | | xanthosine triphosphate pyrophosphatase | cofit | 33 | 67 |
| | Rhizobium sp. OAE497 | ABIE40_RS01630 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | insig. | 33 | 72 |
| o | Klebsiella pneumoniae MKP103 | KDGMDA_04630 | | XTP/dITP diphosphatase | insig. | 32 | 99 |
| o | Enterobacter sp. TBS_079 | MPMX20_03812 | | dITP/XTP pyrophosphatase | strong | 31 | 99 |
| o | Phaeobacter inhibens DSM 17395 | PGA1_c35040 | | nucleoside-triphosphatase RdgB | strong | 27 | 93 |
| o | Dickeya dadantii 3937 | DDA3937_RS17320 | | XTP/dITP diphosphatase | sig. | 29 | 98 |
| o | Rhodanobacter denitrificans MT42 | LRK55_RS11465 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | insig. | 28 | 99 |
| o | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS11740 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | insig. | 28 | 99 |
| | Azospirillum sp. SherDot2 | MPMX19_02575 | | dITP/XTP pyrophosphatase | insig. | 35 | 62 |
| | Azospirillum brasilense Sp245 | AZOBR_RS02200 | | nucleoside-triphosphate diphosphatase | strong | 33 | 64 |
| o | Shewanella amazonensis SB2B | Sama_2482 | | Ham1-like protein (RefSeq) | sig. | 29 | 96 |
| | Pantoea sp. MT58 | IAI47_03585 | | XTP/dITP diphosphatase | insig. | 31 | 99 |
| o | Rhodanobacter sp. FW510-T8 | OKGIIK_12155 | rdgB | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | insig. | 27 | 98 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS22765 | | non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family | insig. | 34 | 64 |
| o | Bosea sp. OAE506 | ABIE41_RS03300 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | insig. | 34 | 64 |
| o | Enterobacter asburiae PDN3 | EX28DRAFT_2992 | | non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family | insig. | 32 | 99 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS04885 | | nucleoside-triphosphate diphosphatase | insig. | 29 | 67 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS21910 | rdgB;go_function=pyrophosphatase | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | insig. | 33 | 67 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_23490 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | insig. | 33 | 67 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS37385 | rdgB;go_function=pyrophosphatase | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | insig. | 33 | 67 |
| o | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS12440 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | no data | 28 | 98 |
| o | Agrobacterium fabrum C58 | Atu0326 | | putative deoxyribonucleotide triphosphate pyrophosphatase | no data | 29 | 93 |
| o | Ralstonia sp. UNC404CL21Col | ABZR87_RS15260 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | insig. | 28 | 96 |
| | Shewanella sp. ANA-3 | Shewana3_1189 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase (RefSeq) | insig. | 34 | 64 |
| | Rhodopseudomonas palustris CGA009 | TX73_001705 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | insig. | 31 | 64 |
| | Dinoroseobacter shibae DFL-12 | Dshi_3462 | | Ham1 family protein (RefSeq) | insig. | 30 | 64 |
| o | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS16800 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | insig. | 27 | 98 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS10660 | | nucleoside-triphosphate diphosphatase | insig. | 31 | 64 |
| o | Dickeya dianthicola 67-19 | HGI48_RS17365 | | XTP/dITP diphosphatase | insig. | 29 | 98 |
| | Erwinia amylovora T8 | OLJFJH_08520 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | sig. | 31 | 99 |
| o | Sphingobium sp. HT1-2 | GFF2618 | | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.66) | cofit | 26 | 96 |
| | Pseudomonas sp. RS175 | PFR28_04248 | | dITP/XTP pyrophosphatase | insig. | 33 | 67 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_08195 | | non-canonical purine NTP pyrophosphatase | sig. | 33 | 67 |
| o | Alteromonas macleodii MIT1002 | MIT1002_00940 | | dITP/XTP pyrophosphatase | insig. | 30 | 99 |
| o | Dickeya dianthicola ME23 | DZA65_RS18455 | | XTP/dITP diphosphatase | insig. | 29 | 98 |
| | Pseudomonas sp. SVBP6 | COO64_RS12970 | rdgB | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | insig. | 32 | 67 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS11905 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | insig. | 29 | 67 |
| o | Shewanella oneidensis MR-1 | SO3358 | | HAM1 protein (NCBI ptt file) | insig. | 28 | 98 |
| | Mycobacterium tuberculosis H37Rv | Rv1341 | | Conserved protein | no data | 29 | 66 |
| | Sinorhizobium meliloti 1021 | SMc01146 | | deoxyribonucleotide triphosphate pyrophosphatase | insig. | 31 | 63 |
| o | Ralstonia solanacearum GMI1000 | RS_RS10835 | | non-canonical purine NTP pyrophosphatase | insig. | 27 | 96 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_4594 | | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) | insig. | 33 | 67 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_2335 | | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) | insig. | 33 | 67 |
| | Pseudomonas stutzeri RCH2 | Psest_0277 | | non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family | insig. | 30 | 67 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS13835 | | non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family | no data | 27 | 96 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_1004 | | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) | insig. | 33 | 67 |
| o | Desulfovibrio vulgaris Miyazaki F | DvMF_1699 | | non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family (RefSeq) | no data | 30 | 95 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_13395 | | non-canonical purine NTP pyrophosphatase | insig. | 33 | 67 |
| | Pseudomonas sp. S08-1 | OH686_11015 | | non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family | insig. | 32 | 67 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS03350 | | non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family | insig. | 31 | 64 |
| | Ralstonia solanacearum UW163 | UW163_RS10370 | | non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family | insig. | 31 | 64 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS16110 | | XTP/dITP diphosphatase | cofit | 32 | 99 |
| o | Rahnella sp. WP5 | EX31_RS02705 | | XTP/dITP diphosphatase | insig. | 32 | 94 |
| | Pseudomonas sp. DMC3 | GFF215 | | dITP/XTP pyrophosphatase | cofit | 31 | 67 |
| | Pseudomonas orientalis W4I3 | QF045_RS01155 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | insig. | 31 | 67 |
| o | Vibrio cholerae E7946 ATCC 55056 | CSW01_02430 | | non-canonical purine NTP pyrophosphatase | insig. | 30 | 98 |
| o | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_03460 | rdgB | XTP/dITP diphosphatase | cofit | 30 | 99 |
| o | Erwinia tracheiphila SCR3 | LU632_RS05450 | | XTP/dITP diphosphatase | insig. | 30 | 99 |
| | Pseudomonas segetis P6 | ACVTMO_RS02985 | rdgB | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | insig. | 30 | 67 |
| o | Serratia liquefaciens MT49 | IAI46_21430 | | XTP/dITP diphosphatase | sig. | 30 | 99 |