| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Methanococcus maripaludis S2 | MMP_RS00690 | | MBL fold metallo-hydrolase | insig. | 100 | 100 |
| o | Methanococcus maripaludis JJ | MMJJ_RS04795 | | MBL fold metallo-hydrolase | insig. | 98 | 100 |
| o | Alteromonas macleodii MIT1002 | MIT1002_03450 | | Beta-lactamase hydrolase-like protein | insig. | 32 | 88 |
| o | Desulfovibrio vulgaris Miyazaki F | DvMF_2853 | | beta-lactamase domain protein (RefSeq) | insig. | 31 | 88 |
| o | Magnetospirillum magneticum AMB-1 | AMB_RS06135 | | MBL fold metallo-hydrolase | cofit | 32 | 87 |
| o | Serratia liquefaciens MT49 | IAI46_08745 | | MBL fold metallo-hydrolase | insig. | 31 | 89 |
| o | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2827 | | Zn-dependent hydrolases, including glyoxylases | insig. | 30 | 89 |
| o | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS20045 | | MBL fold metallo-hydrolase | insig. | 30 | 92 |
| o | Enterobacter sp. TBS_079 | MPMX20_01585 | | Hydroxyacylglutathione hydrolase GloC | insig. | 30 | 91 |
| o | Enterobacter asburiae PDN3 | EX28DRAFT_2009 | | Zn-dependent hydrolases, including glyoxylases | insig. | 29 | 91 |
| | Mycobacterium tuberculosis H37Rv | Rv0634c | | Possible glyoxalase II (hydroxyacylglutathione hydrolase) (GLX II) | insig. | 30 | 90 |
| o | Erwinia tracheiphila SCR3 | LU632_RS09895 | | MBL fold metallo-hydrolase | insig. | 30 | 90 |
| | Mycobacterium tuberculosis H37Rv | Rv2581c | | Possible glyoxalase II (hydroxyacylglutathione hydrolase) (GLX II) | insig. | 29 | 91 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_18065 | | Hydroxyacylglutathione hydrolase GloC | insig. | 31 | 81 |
| | Klebsiella michiganensis M5al | BWI76_RS09865 | | MBL fold hydrolase | insig. | 31 | 83 |
| o | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_20400 | | Hydroxyacylglutathione hydrolase GloC | cofit | 30 | 90 |
| | Pseudomonas stutzeri RCH2 | Psest_3219 | | Zn-dependent hydrolases, including glyoxylases | insig. | 32 | 75 |
| o | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS19735 | | MBL fold hydrolase | insig. | 30 | 90 |
| o | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_14615 | | MBL fold hydrolase | strong | 31 | 88 |
| o | Dickeya dianthicola 67-19 | HGI48_RS12995 | | MBL fold metallo-hydrolase | insig. | 28 | 89 |
| o | Dickeya dadantii 3937 | DDA3937_RS12920 | | MBL fold metallo-hydrolase | insig. | 27 | 96 |
| | Pseudomonas segetis P6 | ACVTMO_RS18280 | | MBL fold metallo-hydrolase | insig. | 31 | 75 |
| o | Dickeya dianthicola ME23 | DZA65_RS13455 | | MBL fold metallo-hydrolase | insig. | 28 | 89 |
| o | Marinobacter adhaerens HP15 | HP15_1191 | | metallo-beta-lactamase family protein | insig. | 29 | 88 |
| | Pseudomonas sp. S08-1 | OH686_06295 | | MBL-fold metallo-hydrolase superfamily | insig. | 31 | 76 |
| o | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS18785 | | MBL fold metallo-hydrolase | strong | 30 | 96 |
| o | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3684 | | Hypothetical metal-binding enzyme, YcbL homolog | insig. | 29 | 89 |
| o | Bacteroides stercoris CC31F | HMPREF1181_RS16810 | | MBL fold metallo-hydrolase | sig. | 28 | 88 |
| | Pseudomonas simiae WCS417 | PS417_04560 | | beta-lactamase | insig. | 31 | 75 |
| o | Bacteroides ovatus ATCC 8483 | BACOVA_04039 | | metallo-beta-lactamase domain protein | strong | 29 | 88 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_2963 | | Hypothetical metal-binding enzyme, YcbL homolog | insig. | 31 | 75 |
| o | Pantoea sp. MT58 | IAI47_12770 | | MBL fold metallo-hydrolase | sig. | 30 | 83 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_1623 | | Hypothetical metal-binding enzyme, YcbL homolog | insig. | 31 | 75 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS04625 | | MBL fold metallo-hydrolase | insig. | 31 | 75 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS04625 | | MBL fold metallo-hydrolase | insig. | 31 | 75 |
| o | Desulfovibrio vulgaris Hildenborough JW710 | DVU2765 | | metallo-beta-lactamase family protein (TIGR) | sig. | 26 | 89 |
| | Acinetobacter baumannii LAC-4 | RR41_RS17080 | | MBL fold metallo-hydrolase | insig. | 32 | 79 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_01115 | | Hydroxyacylglutathione hydrolase GloC | cofit | 31 | 75 |
| | Pseudomonas orientalis W4I3 | QF045_RS07550 | | MBL fold metallo-hydrolase | cofit | 31 | 75 |
| o | Escherichia fergusonii Becca | EFB2_03137 | | Hydroxyacylglutathione hydrolase GloC | insig. | 29 | 89 |
| o | Escherichia coli ECRC100 | OKFHMN_05390 | gloC | hydroxyacylglutathione hydrolase GloC | insig. | 29 | 89 |
| o | Escherichia coli ECRC101 | MCAODC_24780 | gloC | hydroxyacylglutathione hydrolase GloC | sig. | 29 | 89 |
| o | Escherichia coli ECRC102 | NIAGMN_03110 | gloC | hydroxyacylglutathione hydrolase GloC | cofit | 29 | 89 |
| o | Escherichia coli ECRC98 | JDDGAC_09000 | gloC | hydroxyacylglutathione hydrolase GloC | insig. | 29 | 89 |
| o | Escherichia coli ECRC99 | KEDOAH_22345 | gloC | hydroxyacylglutathione hydrolase GloC | no data | 29 | 89 |
| o | Escherichia coli Nissle 1917 | ECOLIN_RS04905 | | hydroxyacylglutathione hydrolase GloC | insig. | 29 | 89 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_03655 | | MBL fold metallo-hydrolase | insig. | 30 | 79 |
| o | Phocaeicola dorei CL03T12C01 | ABI39_RS15105 | | MBL fold metallo-hydrolase | insig. | 30 | 96 |
| o | Escherichia coli ECOR27 | NOLOHH_21950 | gloC | hydroxyacylglutathione hydrolase GloC | insig. | 29 | 89 |
| o | Escherichia coli ECRC62 | BNILDI_20205 | gloC | hydroxyacylglutathione hydrolase GloC | insig. | 29 | 89 |
| o | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_02740 | | Hydroxyacylglutathione hydrolase GloC | insig. | 29 | 89 |
| o | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS04560 | | MBL fold metallo-hydrolase | cofit | 29 | 83 |
| o | Bacteroides thetaiotaomicron VPI-5482 | BT1146 | | putative metallo-beta-lactamase (NCBI ptt file) | strong | 29 | 88 |
| o | Escherichia coli ECOR38 | HEPCGN_23135 | gloC | hydroxyacylglutathione hydrolase GloC | insig. | 29 | 89 |
| | Pseudomonas sp. DMC3 | GFF4448 | | Hydroxyacylglutathione hydrolase GloC | insig. | 30 | 75 |
| o | Rahnella sp. WP5 | EX31_RS18150 | | MBL fold metallo-hydrolase | insig. | 31 | 91 |
| | Pseudomonas sp. SVBP6 | COO64_RS03445 | | MBL fold metallo-hydrolase | insig. | 30 | 75 |
| o | Escherichia coli BL21 | ECD_00931 | | putative metal-binding enzyme | insig. | 29 | 89 |
| o | Escherichia coli BW25113 | b0927 | ycbL | predicted metal-binding enzyme (NCBI) | sig. | 29 | 89 |
| | Pseudomonas sp. BP01 | JOY50_RS19395 | | MBL fold metallo-hydrolase | insig. | 31 | 79 |
| | Azospirillum brasilense Sp245 | AZOBR_RS19250 | | hypothetical protein | no data | 31 | 81 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS44490 | | MBL fold metallo-hydrolase | insig. | 30 | 78 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS08335 | | MBL fold metallo-hydrolase | insig. | 30 | 78 |
| o | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS08505 | | MBL fold metallo-hydrolase | no data | 28 | 88 |
| o | Ralstonia solanacearum GMI1000 | RS_RS16370 | | MBL fold metallo-hydrolase | no data | 28 | 88 |
| o | Ralstonia solanacearum UW163 | UW163_RS05105 | | MBL fold metallo-hydrolase | no data | 28 | 88 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_15160 | | MBL fold metallo-hydrolase | insig. | 30 | 75 |
| o | Azospirillum sp. SherDot2 | MPMX19_04818 | | Hydroxyacylglutathione hydrolase GloC | insig. | 30 | 90 |
| | Caulobacter crescentus NA1000 | CCNA_01241 | | Zn-dependent hydrolase, glyoxalase II family | insig. | 29 | 90 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_01241 | | Zn-dependent hydrolase, glyoxalase II family | cofit | 29 | 90 |
| | Pseudomonas putida KT2440 | PP_0772 | | Metallo-beta-lactamase family protein | insig. | 31 | 78 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF1871 | | Hypothetical metal-binding enzyme, YcbL homolog | insig. | 28 | 83 |
| o | Acidovorax sp. GW101-3H11 | Ac3H11_3348 | | Hypothetical metal-binding enzyme, YcbL homolog | no data | 31 | 81 |
| | Sphingobium sp. HT1-2 | GFF667 | | Hypothetical metal-binding enzyme, YcbL homolog | cofit | 30 | 84 |
| o | Pectobacterium carotovorum WPP14 | HER17_RS12035 | | MBL fold metallo-hydrolase | insig. | 27 | 91 |
| o | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02154 | | Glyoxylase, beta-lactamase superfamily II | insig. | 27 | 96 |
| o | Paraburkholderia graminis OAS925 | ABIE53_000468 | | hydroxyacylglutathione hydrolase | sig. | 27 | 96 |
| o | Paraburkholderia sabiae LMG 24235 | QEN71_RS00645 | | MBL fold metallo-hydrolase | insig. | 28 | 88 |
| | Erwinia amylovora T8 | OLJFJH_16050 | | Hydroxyacylglutathione hydrolase GloC | insig. | 30 | 73 |
| o | Ralstonia solanacearum PSI07 | RPSI07_RS08720 | | MBL fold metallo-hydrolase | no data | 28 | 88 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS05320 | | beta-lactamase | insig. | 32 | 66 |
| | Acinetobacter baumannii LAC-4 | RR41_RS12780 | | MBL fold metallo-hydrolase | insig. | 26 | 87 |
| | Acinetobacter radioresistens SK82 | MPMX26_00296 | | Hydroxyacylglutathione hydrolase GloC | insig. | 31 | 79 |
| o | Shewanella sp. ANA-3 | Shewana3_1493 | | beta-lactamase domain-containing protein (RefSeq) | insig. | 27 | 88 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS06505 | | MBL fold metallo-hydrolase | insig. | 28 | 86 |
| o | Sphingomonas koreensis DSMZ 15582 | Ga0059261_2228 | | Zn-dependent hydrolases, including glyoxylases | insig. | 26 | 95 |
| | Rhodopseudomonas palustris CGA009 | TX73_002945 | | MBL fold metallo-hydrolase | insig. | 29 | 77 |
| | Caulobacter crescentus NA1000 | CCNA_02959 | | Zn-dependent hydrolase, glyoxalase II family | insig. | 29 | 87 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_02959 | | Zn-dependent hydrolase, glyoxalase II family | cofit | 29 | 87 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_12000 | | MBL fold metallo-hydrolase | insig. | 30 | 63 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS01930 | | hypothetical protein | insig. | 28 | 92 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF390 | | Rhodanese-related sulfurtransferase | insig. | 27 | 86 |
| o | Shewanella oneidensis MR-1 | SO3054 | | metallo-beta-lactamase family protein (NCBI ptt file) | sig. | 26 | 88 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_06415 | | MBL fold metallo-hydrolase | insig. | 30 | 82 |
| o | Shewanella loihica PV-4 | Shew_2269 | | beta-lactamase domain-containing protein (RefSeq) | insig. | 27 | 91 |
| o | Xanthobacter sp. DMC5 | GFF3817 | | Hydroxyacylglutathione hydrolase GloC | insig. | 27 | 88 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF3377 | | SoxH protein, homolog | insig. | 26 | 78 |
| o | Ralstonia sp. UNC404CL21Col | ABZR87_RS03825 | | MBL fold metallo-hydrolase | insig. | 27 | 88 |
| o | Rhodospirillum rubrum S1H | Rru_A1522 | | Beta-lactamase-like (NCBI) | no data | 26 | 88 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS00230 | | MBL fold metallo-hydrolase | insig. | 40 | 46 |