| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Pseudomonas stutzeri RCH2 | Psest_3452 | | Zn-dependent hydrolases, including glyoxylases | insig. | 100 | 100 |
| o | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_09160 | | MBL fold metallo-hydrolase | sig. | 39 | 91 |
| o | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS08335 | | rhodanese-like domain-containing protein | insig. | 35 | 92 |
| o | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS25095 | | MBL fold metallo-hydrolase | sig. | 37 | 86 |
| o | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2293 | | Zn-dependent hydrolases, including glyoxylases | insig. | 35 | 91 |
| o | Alteromonas macleodii MIT1002 | MIT1002_02620 | | Beta-lactamase hydrolase-like protein | insig. | 36 | 91 |
| o | Cellulophaga baltica 18 | M666_RS00700 | | MBL fold metallo-hydrolase | insig. | 34 | 89 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_21330 | | MBL fold metallo-hydrolase | insig. | 33 | 91 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS04045 | | MBL fold metallo-hydrolase | insig. | 32 | 91 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_04015 | | MBL fold metallo-hydrolase | insig. | 32 | 73 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS35640 | | MBL fold metallo-hydrolase | insig. | 39 | 51 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS20840 | | beta-lactamase | insig. | 31 | 78 |
| | Paraburkholderia graminis OAS925 | ABIE53_000373 | | sulfur dioxygenase | insig. | 28 | 80 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS08475 | | MBL fold metallo-hydrolase | insig. | 29 | 51 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02289 | | Glyoxylase, beta-lactamase superfamily II | insig. | 27 | 78 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS31635 | | MBL fold metallo-hydrolase | insig. | 29 | 78 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_06415 | | MBL fold metallo-hydrolase | insig. | 30 | 42 |
| | Methylophilus sp. DMC18 | GFF1437 | | Beta-lactamase hydrolase-like protein | insig. | 30 | 49 |
| | Acinetobacter baumannii LAC-4 | RR41_RS12780 | | MBL fold metallo-hydrolase | insig. | 27 | 51 |
| | Shewanella sp. ANA-3 | Shewana3_1493 | | beta-lactamase domain-containing protein (RefSeq) | insig. | 30 | 42 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF390 | | Rhodanese-related sulfurtransferase | insig. | 29 | 63 |
| | Rhodopseudomonas palustris CGA009 | TX73_001890 | | MBL fold metallo-hydrolase | insig. | 33 | 37 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_0937 | | hypothetical protein | insig. | 27 | 51 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF3377 | | SoxH protein, homolog | insig. | 33 | 40 |
| | Alteromonas macleodii MIT1002 | MIT1002_03450 | | Beta-lactamase hydrolase-like protein | insig. | 28 | 45 |
| | Lysobacter sp. OAE881 | ABIE51_RS17110 | | MBL fold metallo-hydrolase | insig. | 30 | 44 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_0945 | | Zn-dependent hydrolases, including glyoxylases | insig. | 33 | 44 |
| | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_20400 | | Hydroxyacylglutathione hydrolase GloC | cofit | 29 | 46 |
| | Erwinia tracheiphila SCR3 | LU632_RS09895 | | MBL fold metallo-hydrolase | insig. | 29 | 46 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS20090 | | Zn-dependent hydrolase | insig. | 28 | 51 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_18065 | | Hydroxyacylglutathione hydrolase GloC | insig. | 29 | 43 |
| | Rhizobium sp. OAE497 | ABIE40_RS12965 | | MBL fold metallo-hydrolase | insig. | 32 | 40 |
| | Sinorhizobium meliloti 1021 | SMc01587 | | hypothetical protein | insig. | 29 | 42 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.1151.1 | | Beta-lactamase | sig. | 29 | 48 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF3246 | | Zn-dependent hydrolases, including glyoxylases | insig. | 30 | 40 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_2009 | | Zn-dependent hydrolases, including glyoxylases | insig. | 29 | 45 |
| | Dechlorosoma suillum PS | Dsui_0929 | | Zn-dependent hydrolase, glyoxylase | cofit | 31 | 46 |
| | Shewanella oneidensis MR-1 | SO3054 | | metallo-beta-lactamase family protein (NCBI ptt file) | sig. | 30 | 42 |
| | Enterobacter sp. TBS_079 | MPMX20_01585 | | Hydroxyacylglutathione hydrolase GloC | insig. | 28 | 45 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF1871 | | Hypothetical metal-binding enzyme, YcbL homolog | insig. | 28 | 42 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS06505 | | MBL fold metallo-hydrolase | insig. | 30 | 45 |
| | Pantoea sp. MT58 | IAI47_12770 | | MBL fold metallo-hydrolase | sig. | 29 | 45 |
| | Escherichia coli ECOR27 | NOLOHH_21950 | gloC | hydroxyacylglutathione hydrolase GloC | insig. | 28 | 45 |
| | Escherichia coli ECRC62 | BNILDI_20205 | gloC | hydroxyacylglutathione hydrolase GloC | insig. | 28 | 45 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_02740 | | Hydroxyacylglutathione hydrolase GloC | insig. | 28 | 45 |
| | Variovorax sp. SCN45 | GFF6926 | | MBL-fold metallo-hydrolase superfamily | insig. | 34 | 37 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS00230 | | MBL fold metallo-hydrolase | insig. | 33 | 37 |
| | Caulobacter crescentus NA1000 | CCNA_01241 | | Zn-dependent hydrolase, glyoxalase II family | insig. | 31 | 41 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_01241 | | Zn-dependent hydrolase, glyoxalase II family | cofit | 31 | 41 |
| | Escherichia coli BL21 | ECD_00931 | | putative metal-binding enzyme | insig. | 28 | 45 |
| | Escherichia fergusonii Becca | EFB2_03137 | | Hydroxyacylglutathione hydrolase GloC | insig. | 28 | 45 |
| | Escherichia coli ECRC100 | OKFHMN_05390 | gloC | hydroxyacylglutathione hydrolase GloC | insig. | 28 | 45 |
| | Escherichia coli ECRC101 | MCAODC_24780 | gloC | hydroxyacylglutathione hydrolase GloC | sig. | 28 | 45 |
| | Escherichia coli ECRC102 | NIAGMN_03110 | gloC | hydroxyacylglutathione hydrolase GloC | cofit | 28 | 45 |
| | Escherichia coli ECRC98 | JDDGAC_09000 | gloC | hydroxyacylglutathione hydrolase GloC | insig. | 28 | 45 |
| | Escherichia coli ECRC99 | KEDOAH_22345 | gloC | hydroxyacylglutathione hydrolase GloC | no data | 28 | 45 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS04905 | | hydroxyacylglutathione hydrolase GloC | insig. | 28 | 45 |
| | Escherichia coli BW25113 | b0927 | ycbL | predicted metal-binding enzyme (NCBI) | sig. | 28 | 45 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3684 | | Hypothetical metal-binding enzyme, YcbL homolog | insig. | 28 | 45 |
| | Dinoroseobacter shibae DFL-12 | Dshi_2517 | | beta-lactamase domain protein (RefSeq) | insig. | 27 | 56 |
| | Ralstonia solanacearum GMI1000 | RS_RS16370 | | MBL fold metallo-hydrolase | no data | 30 | 44 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS08720 | | MBL fold metallo-hydrolase | no data | 30 | 44 |
| | Xanthobacter sp. DMC5 | GFF3817 | | Hydroxyacylglutathione hydrolase GloC | insig. | 32 | 39 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS08505 | | MBL fold metallo-hydrolase | no data | 30 | 43 |
| | Ralstonia solanacearum UW163 | UW163_RS05105 | | MBL fold metallo-hydrolase | no data | 30 | 43 |
| | Caulobacter crescentus NA1000 | CCNA_02959 | | Zn-dependent hydrolase, glyoxalase II family | insig. | 33 | 37 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_02959 | | Zn-dependent hydrolase, glyoxalase II family | cofit | 33 | 37 |
| | Agrobacterium fabrum C58 | Atu2201 | | hydrolase | insig. | 31 | 44 |
| | Klebsiella michiganensis M5al | BWI76_RS09865 | | MBL fold hydrolase | insig. | 28 | 45 |
| | Escherichia coli ECOR38 | HEPCGN_23135 | gloC | hydroxyacylglutathione hydrolase GloC | insig. | 27 | 45 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS04560 | | MBL fold metallo-hydrolase | cofit | 28 | 45 |
| | Rhodospirillum rubrum S1H | Rru_A1522 | | Beta-lactamase-like (NCBI) | no data | 30 | 41 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS00645 | | MBL fold metallo-hydrolase | insig. | 30 | 42 |
| | Sinorhizobium meliloti 1021 | SMa1057 | | hypothetical protein | insig. | 31 | 31 |
| | Shewanella amazonensis SB2B | Sama_2142 | | metallo-beta-lactamase family protein (RefSeq) | sig. | 29 | 39 |
| | Paraburkholderia graminis OAS925 | ABIE53_000468 | | hydroxyacylglutathione hydrolase | sig. | 30 | 42 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_24320 | | MBL fold metallo-hydrolase | insig. | 29 | 40 |
| | Pseudomonas sp. DMC3 | GFF1610 | | putative metallo-hydrolase | cofit | 28 | 41 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_3084 | | Zn-dependent hydrolases, including glyoxylases | insig. | 30 | 40 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2853 | | beta-lactamase domain protein (RefSeq) | insig. | 29 | 46 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS07730 | | MBL fold metallo-hydrolase | insig. | 29 | 46 |
| | Shewanella loihica PV-4 | Shew_2269 | | beta-lactamase domain-containing protein (RefSeq) | insig. | 29 | 44 |
| | Erwinia amylovora T8 | OLJFJH_16050 | | Hydroxyacylglutathione hydrolase GloC | insig. | 28 | 46 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS07460 | | MBL fold metallo-hydrolase | insig. | 29 | 46 |
| | Acinetobacter baumannii LAC-4 | RR41_RS13730 | | MBL fold metallo-hydrolase | insig. | 25 | 47 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS03825 | | MBL fold metallo-hydrolase | insig. | 28 | 44 |
| | Pectobacterium carotovorum WPP14 | HER17_RS12035 | | MBL fold metallo-hydrolase | insig. | 26 | 47 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_2265 | | FIG146518: Zn-dependent hydrolases, including glyoxylases | insig. | 27 | 43 |
| | Marinobacter adhaerens HP15 | HP15_1191 | | metallo-beta-lactamase family protein | insig. | 27 | 45 |
| | Shewanella loihica PV-4 | Shew_3354 | | aminotransferase, class V (RefSeq) | insig. | 31 | 46 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3348 | | Hypothetical metal-binding enzyme, YcbL homolog | no data | 30 | 36 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS19750 | | MBL fold metallo-hydrolase | insig. | 29 | 40 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS11565 | | MBL fold metallo-hydrolase | cofit | 25 | 47 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_0351 | | Zn-dependent hydrolases, including glyoxylases | insig. | 26 | 43 |
| | Sphingobium sp. HT1-2 | GFF5366 | | MBL-fold metallo-hydrolase superfamily | cofit | 30 | 40 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS00780 | | MBL fold metallo-hydrolase | insig. | 29 | 46 |
| | Castellaniella sp019104865 MT123 | ABCV34_RS06060 | | MBL fold metallo-hydrolase | insig. | 28 | 40 |
| | Dickeya dadantii 3937 | DDA3937_RS12920 | | MBL fold metallo-hydrolase | insig. | 26 | 44 |
| | Azospirillum brasilense Sp245 | AZOBR_RS20450 | | hydroxyacylglutathione hydrolase | sig. | 31 | 32 |
| | Pseudomonas putida KT2440 | PP_0052 | | beta-lactamase domain protein, putative hydrolase | insig. | 28 | 40 |