Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| Phaeobacter inhibens DSM 17395 | PGA1_c14760 | | bifunctional enzyme IspDF | insig. | 100 | 100 |
o | Dinoroseobacter shibae DFL-12 | Dshi_1577 | | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (RefSeq) | no data | 57 | 96 |
o | Azospirillum brasilense Sp245 | AZOBR_RS14410 | | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase | no data | 53 | 92 |
o | Magnetospirillum magneticum AMB-1 | AMB_RS11930 | | bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 52 | 93 |
o | Azospirillum sp. SherDot2 | MPMX19_01108 | | Bifunctional enzyme IspD/IspF | no data | 52 | 92 |
o | Caulobacter crescentus NA1000 | CCNA_01812 | | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 52 | 92 |
o | Caulobacter crescentus NA1000 Δfur | CCNA_01812 | | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 52 | 92 |
o | Rhodospirillum rubrum S1H | Rru_A1674 | | bifunctional enzyme, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C- methyl-D-erythritol synthase (NCBI) | no data | 51 | 93 |
o | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS04805 | | bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 49 | 92 |
o | Agrobacterium fabrum C58 | Atu1443 | | bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein | no data | 50 | 92 |
o | Sphingomonas koreensis DSMZ 15582 | Ga0059261_0144 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (EC 4.6.1.12) | no data | 50 | 93 |
o | Rhodopseudomonas palustris CGA009 | TX73_013405 | | bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 49 | 95 |
o | Rhizobium sp. OAE497 | ABIE40_RS09075 | | bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 48 | 92 |
o | Sinorhizobium meliloti 1021 | SMc01040 | | bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 48 | 92 |
o | Bosea sp. OAE506 | ABIE41_RS16800 | | bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 48 | 92 |
| Lysobacter sp. OAE881 | ABIE51_RS06465 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 63 | 39 |
| Desulfovibrio vulgaris Miyazaki F | DvMF_0257 | | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (RefSeq) | no data | 41 | 74 |
| Dyella japonica UNC79MFTsu3.2 | ABZR86_RS06615 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 61 | 38 |
o | Desulfovibrio vulgaris Hildenborough JW710 | DVU1454 | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (TIGR) | no data | 38 | 92 |
| Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.3138.1 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (EC 4.6.1.12) | no data | 56 | 39 |
| Rhodanobacter denitrificans MT42 | LRK55_RS16355 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 59 | 38 |
| Rhodanobacter denitrificans FW104-10B01 | LRK54_RS16630 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 59 | 38 |
| Rhodanobacter sp. FW510-T8 | OKGIIK_08140 | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 57 | 38 |
| Pseudomonas syringae pv. syringae B728a | Psyr_1369 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 54 | 39 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1369 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 54 | 39 |
| Pseudomonas sp. S08-1 | OH686_18160 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 55 | 39 |
| Pseudomonas fluorescens SBW25 | PFLU_RS06405 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 53 | 39 |
| Pseudomonas fluorescens SBW25-INTG | PFLU_RS06405 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 53 | 39 |
| Pseudomonas simiae WCS417 | PS417_06340 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 53 | 39 |
| Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_3110 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (EC 4.6.1.12) | no data | 53 | 39 |
| Pseudomonas stutzeri RCH2 | Psest_2812 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 54 | 38 |
| Pseudomonas fluorescens FW300-N2C3 | AO356_05910 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 53 | 38 |
| Pseudomonas fluorescens GW456-L13 | PfGW456L13_4680 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (EC 4.6.1.12) | no data | 52 | 39 |
| Pseudomonas fluorescens FW300-N2E3 | AO353_16590 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 52 | 39 |
| Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_3042 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (EC 4.6.1.12) | no data | 53 | 38 |
| Shewanella sp. ANA-3 | Shewana3_1119 | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (RefSeq) | no data | 49 | 39 |
| Pseudomonas sp. RS175 | PFR28_00422 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 53 | 38 |
| Pseudomonas putida KT2440 | PP_1618 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 52 | 38 |
| Paraburkholderia sabiae LMG 24235 | QEN71_RS22050 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 52 | 39 |
| Shewanella amazonensis SB2B | Sama_1039 | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (RefSeq) | no data | 49 | 38 |
| Shewanella oneidensis MR-1 | SO3437 | ispF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (NCBI ptt file) | no data | 48 | 39 |
| Synechococcus elongatus PCC 7942 | Synpcc7942_1170 | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 52 | 38 |
| Dechlorosoma suillum PS | Dsui_2391 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 52 | 39 |
| Cupriavidus basilensis FW507-4G11 | RR42_RS07855 | | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase | no data | 53 | 38 |
| Shewanella loihica PV-4 | Shew_1208 | | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (RefSeq) | no data | 50 | 38 |
| Burkholderia phytofirmans PsJN | BPHYT_RS09300 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 49 | 39 |
| Paraburkholderia graminis OAS925 | ABIE53_002097 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 49 | 39 |
| Ralstonia sp. UNC404CL21Col | ABZR87_RS13230 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Ralstonia solanacearum GMI1000 | RS_RS08285 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Ralstonia solanacearum IBSBF1503 | RALBFv3_RS01435 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Ralstonia solanacearum PSI07 | RPSI07_RS16050 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Ralstonia solanacearum UW163 | UW163_RS14745 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_00882 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 49 | 39 |
| Serratia liquefaciens MT49 | IAI46_03760 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Bacteroides stercoris CC31F | HMPREF1181_RS06955 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Parabacteroides merdae CL09T00C40 | HMPREF1078_RS04815 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 51 | 39 |
| Pectobacterium carotovorum WPP14 | HER17_RS04330 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 51 | 39 |
| Dickeya dadantii 3937 | DDA3937_RS16895 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 38 |
| Pantoea sp. MT58 | IAI47_04210 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 51 | 39 |
| Rahnella sp. WP5 | EX31_RS07850 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Dickeya dianthicola 67-19 | HGI48_RS16965 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 38 |
| Dickeya dianthicola ME23 | DZA65_RS18040 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 38 |
| Alteromonas macleodii MIT1002 | MIT1002_00630 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 46 | 38 |
| Bacteroides ovatus ATCC 8483 | BACOVA_01106 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 47 | 39 |
| Herbaspirillum seropedicae SmR1 | HSERO_RS15190 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 38 |
| Bacteroides thetaiotaomicron VPI-5482 | BT3884 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (NCBI ptt file) | no data | 47 | 39 |
| Erwinia tracheiphila SCR3 | LU632_RS06455 | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 48 | 38 |
| Phocaeicola dorei CL03T12C01 | ABI39_RS08100 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 48 | 39 |
| Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS00480 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 48 | 39 |
| Enterobacter sp. TBS_079 | MPMX20_03632 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Escherichia coli BL21 | ECD_02596 | | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Escherichia coli ECOR27 | NOLOHH_12285 | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Escherichia coli ECOR38 | HEPCGN_19650 | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Escherichia coli ECRC101 | OKFHMN_20470 | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Escherichia coli ECRC101 | MCAODC_10995 | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Escherichia coli ECRC102 | NIAGMN_18240 | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Escherichia coli ECRC62 | BNILDI_10835 | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Escherichia coli ECRC98 | JDDGAC_24135 | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Escherichia coli ECRC99 | KEDOAH_07670 | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_00987 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Escherichia coli BW25113 | b2746 | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (NCBI) | no data | 50 | 39 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF4794 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (EC 4.6.1.12) | no data | 50 | 39 |
| Escherichia fergusonii Becca | EFB2_01164 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Escherichia coli Nissle 1917 | ECOLIN_RS15355 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Enterobacter asburiae PDN3 | EX28DRAFT_2842 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (EC 4.6.1.12) | no data | 50 | 39 |
| Vibrio cholerae E7946 ATCC 55056 | CSW01_02810 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 47 | 39 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF4932 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (EC 4.6.1.12) | no data | 48 | 39 |
| Acinetobacter radioresistens SK82 | MPMX26_01675 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 54 | 38 |
| Klebsiella michiganensis M5al | BWI76_RS22670 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 50 | 39 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS01475 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 47 | 38 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_18305 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 45 | 39 |
| Fusobacterium nucleatum SB010 | HUW76_00790 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 46 | 38 |
| Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS23645 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 47 | 39 |
| Kangiella aquimarina DSM 16071 | B158DRAFT_2294 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (EC 4.6.1.12) | no data | 44 | 38 |
| Variovorax sp. OAS795 | ABID97_RS17275 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 48 | 38 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_1506 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 43 | 38 |
| Castellaniella sp019104865 MT123 | ABCV34_RS08600 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 51 | 38 |
| Variovorax sp. SCN45 | GFF410 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (EC 4.6.1.12) | no data | 46 | 38 |
| Acidovorax sp. GW101-3H11 | Ac3H11_332 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (EC 4.6.1.12) | no data | 47 | 39 |
| Marinobacter adhaerens HP15 | HP15_1277 | | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | no data | 49 | 38 |