Homologs of Atu1454 from Agrobacterium fabrum C58

siroheme synthase
SEED: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
KEGG: uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase

Top 100 hits from BLASTp (E < 0.01)

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Orth Species Gene Name Description Fitness %Id Cov
  Agrobacterium fabrum C58 Atu1454 siroheme synthase strong 100 100
o Sinorhizobium meliloti 1021 SMc01053 siroheme synthase strong 77 95
o Rhizobium sp. OAE497 ABIE40_RS09140 siroheme synthase CysG strong 76 94
o Rahnella sp. WP5 EX31_RS07885 uroporphyrinogen-III C-methyltransferase cofit 40 92
o Pseudomonas sp. DMC3 GFF1535 Siroheme synthase strong 39 92
o Pantoea agglomerans CFBP13505 P0401 PagCFBP13505_RS16790 uroporphyrinogen-III C-methyltransferase strong 39 92
  Pseudomonas syringae pv. syringae B728a Psyr_3174 uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase strong 38 92
  Pseudomonas syringae pv. syringae B728a ΔmexB Psyr_3174 uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase cofit 38 92
o Pantoea sp. MT58 IAI47_04175 uroporphyrinogen-III C-methyltransferase strong 39 92
  Pseudomonas fluorescens GW456-L13 PfGW456L13_2656 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) strong 39 92
o Klebsiella michiganensis M5al BWI76_RS22705 siroheme synthase sig. 40 92
o Pseudomonas simiae WCS417 PS417_16465 sirohydrochlorin ferrochelatase strong 38 92
o Serratia liquefaciens MT49 IAI46_03710 uroporphyrinogen-III C-methyltransferase cofit 40 92
o Pseudomonas sp. RS175 PFR28_02603 Siroheme synthase strong 39 92
  Pseudomonas fluorescens FW300-N2C3 AO356_22200 sirohydrochlorin ferrochelatase strong 39 92
  Pseudomonas aeruginosa PA14 IKLFDK_13105 siroheme synthase CysG strong 39 91
  Pseudomonas aeruginosa PUPa3 DQ20_RS35190 cysG;go_function=uroporphyrin-III siroheme synthase CysG strong 38 91
  Pseudomonas fluorescens SBW25 PFLU_RS18505 uroporphyrinogen-III C-methyltransferase strong 38 92
  Pseudomonas fluorescens SBW25-INTG PFLU_RS18505 uroporphyrinogen-III C-methyltransferase strong 38 92
o Erwinia tracheiphila HP pepo 2.2 IJEDHG_17440 cysG siroheme synthase CysG strong 38 91
o Erwinia tracheiphila SCR3 LU632_RS06420 cysG siroheme synthase CysG strong 38 92
  Pseudomonas aeruginosa MRSN321 DY961_RS04165 cysG;go_function=uroporphyrin-III siroheme synthase CysG strong 38 91
  Pseudomonas fluorescens FW300-N2E3 AO353_27625 sirohydrochlorin ferrochelatase no data 39 92
  Pseudomonas fluorescens FW300-N2E2 Pf6N2E2_302 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) strong 39 92
  Pseudomonas lactucae CFBP13502 GEMAOFIL_03620 Siroheme synthase strong 38 92
  Pseudomonas orientalis W4I3 QF045_RS18220 siroheme synthase CysG strong 38 92
  Pseudomonas segetis P6 ACVTMO_RS12565 cysG siroheme synthase CysG no data 39 91
  Pseudomonas fluorescens FW300-N1B4 Pf1N1B4_4065 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) strong 38 92
  Pseudomonas stutzeri RCH2 Psest_2037 uroporphyrin-III C-methyltransferase strong 38 92
  Pseudomonas sp. SVBP6 COO64_RS24155 cysG siroheme synthase CysG strong 37 92
  Methylophilus sp. DMC18 GFF2711 Siroheme synthase no data 37 92
  Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 GFF3700 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) insig. 37 91
  Erwinia amylovora T8 OLJFJH_09320 siroheme synthase CysG strong 38 91
o Pseudomonas putida KT2440 PP_3999 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase strong 39 92
  Rahnella sp. WP5 EX31_RS04680 uroporphyrinogen-III C-methyltransferase insig. 37 92
  Pseudomonas sp. S08-1 OH686_00285 Precorrin-2 oxidase or Sirohydrochlorin ferrochelatase activity of CysG / Uroporphyrinogen-III methyltransferase strong 38 94
o Dickeya dianthicola 67-19 HGI48_RS17000 uroporphyrinogen-III C-methyltransferase cofit 40 92
o Pseudomonas sp. BP01 JOY50_RS06510 cysG siroheme synthase CysG strong 38 92
o Klebsiella pneumoniae MKP103 KDGMDA_03280 siroheme synthase CysG insig. 38 92
  Pectobacterium carotovorum WPP14 HER17_RS04280 siroheme synthase CysG cofit 38 92
  Escherichia coli ECOR38 HEPCGN_16010 cysG siroheme synthase CysG strong 36 91
  Escherichia coli ECOR27 NOLOHH_08980 cysG siroheme synthase CysG strong 36 91
  Escherichia coli ECRC62 BNILDI_02540 cysG siroheme synthase CysG strong 36 91
  Enterobacter asburiae PDN3 EX28DRAFT_4160 uroporphyrin-III C-methyltransferase insig. 36 92
  Enterobacter sp. TBS_079 MPMX20_03639 Siroheme synthase insig. 38 92
  Pantoea agglomerans CFBP13505 P0401 PagCFBP13505_RS21670 uroporphyrinogen-III C-methyltransferase cofit 37 92
  Escherichia coli ECRC100 OKFHMN_17180 cysG siroheme synthase CysG strong 36 91
  Escherichia coli ECRC101 MCAODC_07710 cysG siroheme synthase CysG strong 36 91
  Escherichia coli ECRC102 NIAGMN_14950 cysG siroheme synthase CysG strong 36 91
  Escherichia coli ECRC98 JDDGAC_20810 cysG siroheme synthase CysG strong 36 91
  Escherichia coli ECRC99 KEDOAH_10960 cysG siroheme synthase CysG no data 36 91
  Escherichia coli BL21 ECD_03219 fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase strong 36 92
  Escherichia fergusonii Becca EFB2_00454 Siroheme synthase insig. 36 92
  Escherichia coli HS(pFamp)R (ATCC 700891) OHPLBJKB_00334 Siroheme synthase insig. 36 92
  Escherichia coli Nissle 1917 ECOLIN_RS19285 siroheme synthase CysG cofit 36 92
  Escherichia coli BW25113 b3368 cysG fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) strong 36 92
o Dickeya dianthicola ME23 DZA65_RS18075 uroporphyrinogen-III C-methyltransferase strong 40 92
o Dickeya dadantii 3937 DDA3937_RS16930 uroporphyrinogen-III C-methyltransferase strong 40 92
  Alteromonas macleodii MIT1002 MIT1002_00665 Siroheme synthase no data 35 92
  Enterobacter asburiae PDN3 EX28DRAFT_2849 uroporphyrin-III C-methyltransferase strong 39 92
o Brevundimonas sp. GW460-12-10-14-LB2 A4249_RS09675 siroheme synthase CysG strong 41 94
  Enterobacter sp. TBS_079 MPMX20_04271 Siroheme synthase sig. 35 92
  Klebsiella pneumoniae MKP103 KDGMDA_06880 siroheme synthase CysG insig. 35 92
  Klebsiella michiganensis M5al BWI76_RS26055 siroheme synthase strong 36 92
  Pectobacterium carotovorum WPP14 HER17_RS01835 siroheme synthase CysG insig. 36 92
o Rhodospirillum rubrum S1H Rru_A1933 Uroporphyrin-III C-methyltransferase (NCBI) sig. 45 86
o Dinoroseobacter shibae DFL-12 Dshi_1671 uroporphyrin-III C-methyltransferase (RefSeq) insig. 42 82
o Acinetobacter radioresistens SK82 MPMX26_00706 Siroheme synthase no data 33 92
o Rhodopseudomonas palustris CGA009 TX73_021850 siroheme synthase CysG cofit 39 93
  Serratia liquefaciens MT49 IAI46_23670 uroporphyrinogen-III C-methyltransferase insig. 34 92
  Agrobacterium fabrum C58 Atu3899 siroheme synthase insig. 37 95
  Dinoroseobacter shibae DFL-12 Dshi_1155 uroporphyrin-III C-methyltransferase (RefSeq) no data 42 91
  Kangiella aquimarina DSM 16071 B158DRAFT_2163 uroporphyrin-III C-methyltransferase insig. 33 93
  Acinetobacter baumannii LAC-4 RR41_RS03950 siroheme synthase CysG sig. 33 92
o Rhodanobacter sp000427505 FW510-R12 LRK53_RS09200 siroheme synthase CysG strong 40 92
  Bosea sp. OAE506 ABIE41_RS15910 siroheme synthase CysG no data 38 99
o Castellaniella sp019104865 MT123 ABCV34_RS00210 siroheme synthase CysG strong 38 92
o Rhodanobacter sp. FW510-T8 OKGIIK_05980 cysG siroheme synthase CysG strong 41 91
  Dyella japonica UNC79MFTsu3.2 ABZR86_RS05880 siroheme synthase CysG strong 38 93
o Lysobacter sp. OAE881 ABIE51_RS15855 siroheme synthase CysG strong 39 92
o Rhodanobacter denitrificans FW104-10B01 LRK54_RS00910 siroheme synthase CysG cofit 40 91
  Xanthobacter sp. DMC5 GFF1971 Siroheme synthase no data 37 92
  Dyella japonica UNC79MFTsu3.2 ABZR86_RS03870 siroheme synthase CysG insig. 38 97
o Rhodanobacter denitrificans MT42 LRK55_RS00685 siroheme synthase CysG insig. 40 91
  Pectobacterium carotovorum WPP14 HER17_RS07340 uroporphyrinogen-III C-methyltransferase insig. 47 53
  Shewanella sp. ANA-3 Shewana3_0862 uroporphyrinogen-III C-methyltransferase (RefSeq) strong 46 49
  Caulobacter crescentus NA1000 CCNA_01175 uroporphyrin-III C-methyltransferase strong 49 51
  Caulobacter crescentus NA1000 Δfur CCNA_01175 uroporphyrin-III C-methyltransferase cofit 49 51
  Shewanella loihica PV-4 Shew_0672 uroporphyrin-III C-methyltransferase (RefSeq) cofit 45 49
  Dickeya dianthicola ME23 DZA65_RS14740 uroporphyrinogen-III C-methyltransferase insig. 44 51
  Shewanella oneidensis MR-1 SO3728 cobA uroporphyrin-III C-methyltransferase (NCBI ptt file) strong 45 49
  Dickeya dadantii 3937 DDA3937_RS14080 uroporphyrinogen-III C-methyltransferase sig. 44 51
  Dickeya dianthicola 67-19 HGI48_RS14080 uroporphyrinogen-III C-methyltransferase insig. 44 51
  Rahnella sp. WP5 EX31_RS09100 uroporphyrinogen-III C-methyltransferase insig. 44 48
  Pantoea sp. MT58 IAI47_11160 uroporphyrinogen-III C-methyltransferase strong 44 48
  Sinorhizobium meliloti 1021 SM_b20987 siroheme synthase insig. 38 68
  Shewanella amazonensis SB2B Sama_2892 uroporphyrin-III C-methyltransferase (RefSeq) strong 44 49
  Dechlorosoma suillum PS Dsui_2969 uroporphyrin-III C-methyltransferase cofit 46 51
  Pseudomonas aeruginosa PA14 IKLFDK_22885 uroporphyrinogen-III C-methyltransferase insig. 43 48
  Pseudomonas sp. RS175 PFR28_01046 Uroporphyrinogen-III C-methyltransferase insig. 44 49