| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
|---|
| | Bacteroides thetaiotaomicron VPI-5482 | BT1607 | | methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase (NCBI ptt file) | strong | 100 | 100 |
| o | Bacteroides ovatus ATCC 8483 | BACOVA_04344 | | tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein | strong | 96 | 100 |
| o | Bacteroides stercoris CC31F | HMPREF1181_RS11305 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | strong | 96 | 100 |
| o | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS15075 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | strong | 96 | 100 |
| o | Phocaeicola dorei CL03T12C01 | ABI39_RS10870 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | strong | 96 | 100 |
| o | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS14700 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | strong | 83 | 99 |
| o | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_07145 | | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase | no data | 68 | 100 |
| o | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_4643 | | 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase | no data | 64 | 99 |
| o | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS08950 | | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase | no data | 63 | 99 |
| o | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS09400 | | bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase | no data | 61 | 100 |
| o | Desulfovibrio vulgaris Hildenborough JW710 | DVU0323 | folD | methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase (TIGR) | no data | 47 | 98 |
| o | Rhodospirillum rubrum S1H | Rru_A0557 | | Methenyltetrahydrofolate cyclohydrolase (NCBI) | no data | 50 | 98 |
| o | Bosea sp. OAE506 | ABIE41_RS08995 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | insig. | 50 | 98 |
| o | Cupriavidus basilensis FW507-4G11 | RR42_RS07345 | | methenyltetrahydrofolate cyclohydrolase | no data | 48 | 98 |
| o | Dechlorosoma suillum PS | Dsui_0093 | | 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase | no data | 47 | 98 |
| o | Desulfovibrio vulgaris Miyazaki F | DvMF_1809 | | Methenyltetrahydrofolate cyclohydrolase (RefSeq) | no data | 47 | 98 |
| o | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF4894 | | Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) | no data | 49 | 96 |
| o | Kangiella aquimarina DSM 16071 | B158DRAFT_1028 | | methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)/5,10-methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) | no data | 49 | 97 |
| o | Acidovorax sp. GW101-3H11 | Ac3H11_4096 | | Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) | no data | 49 | 98 |
| o | Variovorax sp. SCN45 | GFF964 | | Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) / Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) | no data | 48 | 98 |
| o | Erwinia tracheiphila SCR3 | LU632_RS15195 | folD | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 48 | 97 |
| o | Vibrio cholerae E7946 ATCC 55056 | CSW01_09720 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | cofit | 47 | 97 |
| o | Dickeya dianthicola ME23 | DZA65_RS15960 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 48 | 97 |
| o | Dickeya dianthicola 67-19 | HGI48_RS15155 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 48 | 97 |
| o | Variovorax sp. OAS795 | ABID97_RS14085 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 47 | 98 |
| o | Dickeya dadantii 3937 | DDA3937_RS15075 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 48 | 97 |
| o | Rahnella sp. WP5 | EX31_RS22835 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 48 | 97 |
| o | Shewanella sp. ANA-3 | Shewana3_2663 | | methenyltetrahydrofolate cyclohydrolase (RefSeq) | no data | 46 | 98 |
| o | Alteromonas macleodii MIT1002 | MIT1002_02770 | | hypothetical protein | no data | 46 | 97 |
| o | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF4447 | | Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) | no data | 48 | 97 |
| o | Shewanella oneidensis MR-1 | SO1792 | folD | methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase (NCBI ptt file) | no data | 45 | 98 |
| o | Shewanella loihica PV-4 | Shew_2510 | | methylenetetrahydrofolate dehydrogenase (NADP(+)) (RefSeq) | no data | 46 | 98 |
| o | Pectobacterium carotovorum WPP14 | HER17_RS06505 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 47 | 97 |
| o | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS01685 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 49 | 96 |
| o | Ralstonia solanacearum UW163 | UW163_RS14995 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 49 | 96 |
| o | Herbaspirillum seropedicae SmR1 | HSERO_RS07295 | | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase | no data | 47 | 98 |
| o | Azospirillum brasilense Sp245 | AZOBR_RS00650 | | 5 10-methylene-tetrahydrofolate dehydrogenase | no data | 49 | 96 |
| o | Ralstonia solanacearum GMI1000 | RS_RS08040 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase | no data | 49 | 96 |
| o | Pantoea sp. MT58 | IAI47_14320 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 46 | 97 |
| o | Pseudomonas putida KT2440 | PP_1945 | | methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase | insig. | 44 | 99 |
| o | Ralstonia solanacearum PSI07 | RPSI07_RS15800 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 49 | 96 |
| o | Burkholderia phytofirmans PsJN | BPHYT_RS12865 | | bifunctional protein FolD | no data | 49 | 96 |
| o | Pseudomonas syringae pv. syringae B728a | Psyr_2225 | | methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+) | insig. | 47 | 99 |
| o | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_2225 | | methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+) | insig. | 47 | 99 |
| o | Escherichia fergusonii Becca | EFB2_03532 | | Bifunctional protein FolD protein | no data | 46 | 97 |
| o | Escherichia coli ECOR38 | HEPCGN_06445 | | Bifunctional protein FolD | no data | 46 | 97 |
| o | Escherichia coli ECRC101 | OKFHMN_07805 | | Bifunctional protein FolD | no data | 46 | 97 |
| o | Escherichia coli ECRC101 | MCAODC_27025 | | Bifunctional protein FolD | no data | 46 | 97 |
| o | Escherichia coli ECRC102 | NIAGMN_05860 | | Bifunctional protein FolD | no data | 46 | 97 |
| o | Escherichia coli ECRC98 | JDDGAC_11455 | | Bifunctional protein FolD | no data | 46 | 97 |
| o | Escherichia coli ECRC99 | KEDOAH_20165 | | Bifunctional protein FolD | no data | 46 | 97 |
| o | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_03152 | | Bifunctional protein FolD protein | no data | 46 | 97 |
| o | Escherichia coli Nissle 1917 | ECOLIN_RS03065 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 46 | 97 |
| o | Escherichia coli BL21 | ECD_00479 | | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase | no data | 46 | 97 |
| o | Escherichia coli ECOR27 | NOLOHH_00795 | | Bifunctional protein FolD | no data | 46 | 97 |
| o | Escherichia coli BW25113 | b0529 | folD | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase (NCBI) | no data | 46 | 97 |
| o | Klebsiella michiganensis M5al | BWI76_RS07100 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase | no data | 46 | 97 |
| o | Paraburkholderia graminis OAS925 | ABIE53_002796 | | methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase | no data | 50 | 96 |
| o | Ralstonia sp. UNC404CL21Col | ABZR87_RS13485 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 48 | 96 |
| o | Escherichia coli ECRC62 | BNILDI_22225 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 46 | 97 |
| o | Synechococcus elongatus PCC 7942 | Synpcc7942_0777 | folD | Methenyltetrahydrofolate cyclohydrolase | no data | 44 | 97 |
| o | Serratia liquefaciens MT49 | IAI46_05400 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 45 | 97 |
| o | Magnetospirillum magneticum AMB-1 | AMB_RS22130 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase | no data | 49 | 97 |
| o | Paraburkholderia sabiae LMG 24235 | QEN71_RS05700 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 48 | 98 |
| o | Shewanella amazonensis SB2B | Sama_1222 | | methylenetetrahydrofolate dehydrogenase (NADP(+)) (RefSeq) | no data | 45 | 98 |
| o | Pseudomonas sp. S08-1 | OH686_03670 | | Methenyltetrahydrofolate cyclohydrolase / Methylenetetrahydrofolate dehydrogenase (NADP+) | no data | 46 | 97 |
| o | Sinorhizobium meliloti 1021 | SMc03059 | | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase | no data | 45 | 97 |
| o | Enterobacter asburiae PDN3 | EX28DRAFT_2449 | | 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase | no data | 45 | 97 |
| o | Enterobacter sp. TBS_079 | MPMX20_01107 | | Bifunctional protein FolD protein | no data | 45 | 97 |
| o | Pseudomonas fluorescens FW300-N2E3 | AO353_20145 | | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase | no data | 45 | 98 |
| o | Caulobacter crescentus NA1000 | CCNA_01275 | | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase | no data | 45 | 98 |
| o | Caulobacter crescentus NA1000 Δfur | CCNA_01275 | | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase | cofit | 45 | 98 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS33970 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | insig. | 45 | 98 |
| o | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_00463 | | methenyltetrahydrofolate cyclohydrolase /5,10-methylenetetrahydrofolate dehydrogenase (NADP+) | no data | 49 | 96 |
| o | Pseudomonas stutzeri RCH2 | Psest_2301 | | 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase | no data | 45 | 98 |
| o | Castellaniella sp019104865 MT123 | ABCV34_RS04175 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 46 | 99 |
| o | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_2221 | | Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) | no data | 45 | 98 |
| o | Pseudomonas simiae WCS417 | PS417_17265 | | methenyltetrahydrofolate cyclohydrolase | no data | 45 | 98 |
| o | Pseudomonas sp. RS175 | PFR28_01223 | | Bifunctional protein FolD protein | no data | 45 | 98 |
| | Pseudomonas putida KT2440 | PP_2265 | | methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase | no data | 45 | 98 |
| o | Pseudomonas fluorescens GW456-L13 | PfGW456L13_2550 | | Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) | no data | 45 | 98 |
| | Sinorhizobium meliloti 1021 | SMc02604 | | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase | insig. | 44 | 99 |
| o | Azospirillum sp. SherDot2 | MPMX19_02743 | | Bifunctional protein FolD protein | no data | 48 | 96 |
| o | Phaeobacter inhibens DSM 17395 | PGA1_c06010 | | bifunctional protein FolD | no data | 46 | 99 |
| o | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_3943 | | Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) | no data | 45 | 98 |
| o | Pseudomonas fluorescens FW300-N2C3 | AO356_01775 | | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase | no data | 44 | 98 |
| o | Rhizobium sp. OAE497 | ABIE40_RS03150 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 45 | 98 |
| o | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS06645 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase | no data | 45 | 96 |
| o | Pseudomonas fluorescens SBW25 | PFLU_RS19200 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 45 | 98 |
| o | Pseudomonas fluorescens SBW25-INTG | PFLU_RS19200 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 45 | 98 |
| o | Marinobacter adhaerens HP15 | HP15_2187 | | methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase | no data | 45 | 97 |
| o | Sphingomonas koreensis DSMZ 15582 | Ga0059261_2527 | | 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase | no data | 47 | 98 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_30100 | | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase | insig. | 46 | 97 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_1743 | | methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+) | no data | 45 | 98 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1743 | | methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+) | no data | 45 | 98 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS11390 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | insig. | 46 | 96 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS11390 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | insig. | 46 | 96 |
| o | Agrobacterium fabrum C58 | Atu0589 | | methylenetetrahydrofolate dehydrogenase | no data | 43 | 99 |
| o | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS00100 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 44 | 98 |
| o | Rhodopseudomonas palustris CGA009 | TX73_002145 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | no data | 44 | 97 |