Conservation of cofitness between CSW01_02450 and CSW01_13285 in Vibrio cholerae E7946 ATCC 55056

109 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_02450 pyrroline-5-carboxylate reductase 1.0 CSW01_13285 ribulose-phosphate 3-epimerase 0.87 2
Pectobacterium carotovorum WPP14 0.69 HER17_RS03805 pyrroline-5-carboxylate reductase 0.76 HER17_RS01795 ribulose-phosphate 3-epimerase — —
Serratia liquefaciens MT49 0.69 IAI46_21415 pyrroline-5-carboxylate reductase 0.76 IAI46_23685 ribulose-phosphate 3-epimerase low > 86
Dickeya dadantii 3937 0.68 DDA3937_RS17305 pyrroline-5-carboxylate reductase 0.75 DDA3937_RS19530 ribulose-phosphate 3-epimerase — —
Dickeya dianthicola 67-19 0.68 HGI48_RS17350 pyrroline-5-carboxylate reductase 0.76 HGI48_RS19660 ribulose-phosphate 3-epimerase — —
Dickeya dianthicola ME23 0.67 DZA65_RS18440 pyrroline-5-carboxylate reductase 0.76 DZA65_RS20745 ribulose-phosphate 3-epimerase — —
Rahnella sp. WP5 0.65 EX31_RS02690 pyrroline-5-carboxylate reductase 0.74 EX31_RS04705 ribulose-phosphate 3-epimerase — —
Alteromonas macleodii MIT1002 0.60 MIT1002_03062 Pyrroline-5-carboxylate reductase 0.74 MIT1002_00441 Ribulose-phosphate 3-epimerase — —
Shewanella oneidensis MR-1 0.57 SO3354 proC pyrroline-5-carboxylate reductase (NCBI ptt file) 0.78 SO0292 rpe ribulose-phosphate 3-epimerase (NCBI ptt file) — —
Shewanella sp. ANA-3 0.56 Shewana3_1193 pyrroline-5-carboxylate reductase (RefSeq) 0.78 Shewana3_3888 ribulose-5-phosphate 3-epimerase (RefSeq) — —
Shewanella loihica PV-4 0.52 Shew_1136 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.77 Shew_0219 ribulose-phosphate 3-epimerase (RefSeq) — —
Shewanella amazonensis SB2B 0.50 Sama_2478 pyrroline-5-carboxylate reductase (RefSeq) 0.77 Sama_3362 ribulose-phosphate 3-epimerase (RefSeq) — —
Kangiella aquimarina DSM 16071 0.42 B158DRAFT_0197 pyrroline-5-carboxylate reductase 0.69 B158DRAFT_0267 ribulose-phosphate 3-epimerase — —
Marinobacter adhaerens HP15 0.38 HP15_287 pyrroline-5-carboxylate reductase 0.69 HP15_3286 ribulose-phosphate 3-epimerase-like protein — —
Acinetobacter radioresistens SK82 0.38 MPMX26_00572 Pyrroline-5-carboxylate reductase 0.73 MPMX26_02569 Ribulose-phosphate 3-epimerase — —
Pseudomonas sp. BP01 0.37 JOY50_RS20905 proC pyrroline-5-carboxylate reductase 0.71 JOY50_RS18210 rpe ribulose-phosphate 3-epimerase — —
Pseudomonas fluorescens SBW25 0.37 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.71 PFLU_RS27390 ribulose-phosphate 3-epimerase — —
Pseudomonas fluorescens SBW25-INTG 0.37 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.71 PFLU_RS27390 ribulose-phosphate 3-epimerase — —
Paraburkholderia graminis OAS925 0.37 ABIE53_000840 pyrroline-5-carboxylate reductase 0.66 ABIE53_003638 ribulose-phosphate 3-epimerase low > 113
Pseudomonas putida KT2440 0.37 PP_5095 pyrroline-5-carboxylate reductase 0.71 PP_0415 ribulose-5-phosphate 3-epimerase — —
Lysobacter sp. OAE881 0.37 ABIE51_RS16065 pyrroline-5-carboxylate reductase 0.66 ABIE51_RS04135 ribulose-phosphate 3-epimerase — —
Pseudomonas sp. SVBP6 0.36 COO64_RS12995 proC pyrroline-5-carboxylate reductase 0.71 COO64_RS22440 rpe ribulose-phosphate 3-epimerase — —
Pseudomonas simiae WCS417 0.36 PS417_26730 pyrroline-5-carboxylate reductase 0.71 PS417_25735 ribulose-phosphate 3-epimerase — —
Dechlorosoma suillum PS 0.36 Dsui_0602 pyrroline-5-carboxylate reductase 0.66 Dsui_0221 ribulose-phosphate 3-epimerase — —
Paraburkholderia sabiae LMG 24235 0.36 QEN71_RS26600 pyrroline-5-carboxylate reductase 0.66 QEN71_RS27540 ribulose-phosphate 3-epimerase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.36 Psyr_0476 pyrroline-5-carboxylate reductase 0.71 Psyr_4611 ribulose-5-phosphate 3-epimerase — —
Pseudomonas syringae pv. syringae B728a 0.36 Psyr_0476 pyrroline-5-carboxylate reductase 0.71 Psyr_4611 ribulose-5-phosphate 3-epimerase — —
Pseudomonas fluorescens FW300-N2E3 0.36 AO353_08165 pyrroline-5-carboxylate reductase 0.70 AO353_07240 ribulose phosphate epimerase — —
Pseudomonas fluorescens FW300-N2C3 0.36 AO356_13420 pyrroline-5-carboxylate reductase 0.70 AO356_14410 ribulose phosphate epimerase — —
Pseudomonas fluorescens GW456-L13 0.35 PfGW456L13_1010 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.70 PfGW456L13_1215 Ribulose-phosphate 3-epimerase (EC 5.1.3.1) — —
Paraburkholderia bryophila 376MFSha3.1 0.35 H281DRAFT_04679 pyrroline-5-carboxylate reductase 0.66 H281DRAFT_05717 ribulose-5-phosphate 3-epimerase low > 103
Pseudomonas fluorescens FW300-N2E2 0.35 Pf6N2E2_4600 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.71 Pf6N2E2_4820 Ribulose-phosphate 3-epimerase (EC 5.1.3.1) — —
Burkholderia phytofirmans PsJN 0.35 BPHYT_RS03490 pyrroline-5-carboxylate reductase 0.67 BPHYT_RS17380 ribulose-phosphate 3-epimerase — —
Pseudomonas aeruginosa PA14 0.35 IKLFDK_23455 pyrroline-5-carboxylate reductase 0.70 IKLFDK_22375 ribulose-phosphate 3-epimerase — —
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS01230 pyrroline-5-carboxylate reductase 0.64 ABZR87_RS02130 ribulose-phosphate 3-epimerase — —
Pseudomonas sp. RS175 0.35 PFR28_04243 Pyrroline-5-carboxylate reductase 0.70 PFR28_04049 Ribulose-phosphate 3-epimerase — —
Pseudomonas sp. S08-1 0.35 OH686_10980 pyrroline-5-carboxylate reductase 0.70 OH686_15115 ribulose-phosphate 3-epimerase — —
Pseudomonas fluorescens FW300-N1B4 0.35 Pf1N1B4_2341 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.71 Pf1N1B4_2543 Ribulose-phosphate 3-epimerase (EC 5.1.3.1) — —
Pseudomonas stutzeri RCH2 0.34 Psest_0283 pyrroline-5-carboxylate reductase 0.71 Psest_3652 ribulose-phosphate 3-epimerase — —
Pseudomonas sp. DMC3 0.34 GFF210 Pyrroline-5-carboxylate reductase 0.69 GFF22 Ribulose-phosphate 3-epimerase — —
Ralstonia solanacearum GMI1000 0.33 RS_RS13440 pyrroline-5-carboxylate reductase 0.63 RS_RS14420 ribulose-phosphate 3-epimerase — —
Ralstonia solanacearum IBSBF1503 0.32 RALBFv3_RS05580 pyrroline-5-carboxylate reductase 0.64 RALBFv3_RS06475 ribulose-phosphate 3-epimerase — —
Ralstonia solanacearum UW163 0.32 UW163_RS08045 pyrroline-5-carboxylate reductase 0.64 UW163_RS07150 ribulose-phosphate 3-epimerase — —
Dyella japonica UNC79MFTsu3.2 0.32 ABZR86_RS10425 pyrroline-5-carboxylate reductase 0.71 ABZR86_RS12200 ribulose-phosphate 3-epimerase low > 74
Variovorax sp. OAS795 0.32 ABID97_RS01555 pyrroline-5-carboxylate reductase 0.59 ABID97_RS04905 ribulose-phosphate 3-epimerase — —
Ralstonia solanacearum PSI07 0.32 RPSI07_RS11720 pyrroline-5-carboxylate reductase 0.64 RPSI07_RS10765 ribulose-phosphate 3-epimerase — —
Acidovorax sp. GW101-3H11 0.32 Ac3H11_788 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.57 Ac3H11_757 Ribulose-phosphate 3-epimerase (EC 5.1.3.1) — —
Castellaniella sp019104865 MT123 0.32 ABCV34_RS03610 pyrroline-5-carboxylate reductase 0.59 ABCV34_RS10270 ribulose-phosphate 3-epimerase — —
Methylophilus sp. DMC18 0.31 GFF863 Pyrroline-5-carboxylate reductase 0.64 GFF2051 Ribulose-phosphate 3-epimerase — —
Variovorax sp. SCN45 0.31 GFF5553 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.59 GFF6246 Ribulose-phosphate 3-epimerase (EC 5.1.3.1) — —
Xanthomonas campestris pv. campestris strain 8004 0.30 Xcc-8004.1710.1 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.64 Xcc-8004.605.1 Ribulose-phosphate 3-epimerase (EC 5.1.3.1) — —
Rhodanobacter sp000427505 FW510-R12 0.30 LRK53_RS05680 pyrroline-5-carboxylate reductase 0.66 LRK53_RS17105 ribulose-phosphate 3-epimerase 0.69 12
Cupriavidus basilensis FW507-4G11 0.30 RR42_RS17360 pyrroline-5-carboxylate reductase 0.68 RR42_RS18285 ribulose-phosphate 3-epimerase — —
Rhodanobacter sp. FW510-T8 0.30 OKGIIK_11135 proC pyrroline-5-carboxylate reductase 0.62 OKGIIK_12435 rpe ribulose-phosphate 3-epimerase — —
Rhodanobacter denitrificans FW104-10B01 0.29 LRK54_RS04260 pyrroline-5-carboxylate reductase 0.63 LRK54_RS11390 ribulose-phosphate 3-epimerase — —
Rhodanobacter denitrificans MT42 0.29 LRK55_RS04030 pyrroline-5-carboxylate reductase 0.64 LRK55_RS11120 ribulose-phosphate 3-epimerase — —
Herbaspirillum seropedicae SmR1 0.29 HSERO_RS18990 pyrroline-5-carboxylate reductase 0.67 HSERO_RS19425 ribulose-phosphate 3-epimerase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.28 GFF2806 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.60 GFF2197 Ribulose-phosphate 3-epimerase (EC 5.1.3.1) low > 90
Magnetospirillum magneticum AMB-1 0.28 AMB_RS02820 pyrroline-5-carboxylate reductase 0.49 AMB_RS06980 ribulose-phosphate 3-epimerase — —
Escherichia fergusonii Becca 0.27 EFB2_03670 Pyrroline-5-carboxylate reductase 0.77 EFB2_00442 Ribulose-phosphate 3-epimerase — —
Enterobacter asburiae PDN3 0.27 EX28DRAFT_2585 pyrroline-5-carboxylate reductase 0.78 EX28DRAFT_4156 ribulose-phosphate 3-epimerase low > 76
Enterobacter sp. TBS_079 0.27 MPMX20_00976 Pyrroline-5-carboxylate reductase 0.77 MPMX20_04275 Ribulose-phosphate 3-epimerase low > 85
Klebsiella michiganensis M5al 0.27 BWI76_RS06170 pyrroline-5-carboxylate reductase 0.77 BWI76_RS26070 ribulose-phosphate 3-epimerase — —
Escherichia coli BW25113 0.27 b0386 proC pyrroline-5-carboxylate reductase (NCBI) 0.77 b3386 rpe ribulose-phosphate 3-epimerase (NCBI) low > 76
Escherichia coli ECOR27 0.27 NOLOHH_01535 proC pyrroline-5-carboxylate reductase 0.77 NOLOHH_08920 dam adenine-specific DNA-methyltransferase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.27 OHPLBJKB_03288 Pyrroline-5-carboxylate reductase 0.77 OHPLBJKB_00317 Ribulose-phosphate 3-epimerase — —
Escherichia coli ECRC62 0.27 BNILDI_22950 proC pyrroline-5-carboxylate reductase 0.77 BNILDI_02600 dam adenine-specific DNA-methyltransferase — —
Escherichia coli BL21 0.27 ECD_00333 pyrroline-5-carboxylate reductase, NAD(P)-binding 0.77 ECD_03238 D-ribulose-5-phosphate 3-epimerase low > 61
Escherichia coli ECOR38 0.27 HEPCGN_07250 proC pyrroline-5-carboxylate reductase 0.77 HEPCGN_15950 rpe ribulose-phosphate 3-epimerase low > 87
Escherichia coli Nissle 1917 0.27 ECOLIN_RS02345 pyrroline-5-carboxylate reductase 0.77 ECOLIN_RS19345 ribulose-phosphate 3-epimerase low > 55
Escherichia coli ECRC99 0.27 KEDOAH_19355 proC pyrroline-5-carboxylate reductase 0.77 KEDOAH_11010 dam adenine-specific DNA-methyltransferase — —
Escherichia coli ECRC101 0.27 MCAODC_27835 proC pyrroline-5-carboxylate reductase 0.77 MCAODC_07660 dam adenine-specific DNA-methyltransferase — —
Escherichia coli ECRC98 0.27 JDDGAC_12265 proC pyrroline-5-carboxylate reductase 0.77 JDDGAC_20760 dam adenine-specific DNA-methyltransferase — —
Escherichia coli ECRC102 0.27 NIAGMN_06665 proC pyrroline-5-carboxylate reductase 0.77 NIAGMN_14900 dam adenine-specific DNA-methyltransferase — —
Escherichia coli ECRC100 0.27 OKFHMN_08610 proC pyrroline-5-carboxylate reductase 0.77 OKFHMN_17130 dam adenine-specific DNA-methyltransferase — —
Erwinia amylovora T8 0.26 OLJFJH_18285 pyrroline-5-carboxylate reductase 0.76 OLJFJH_04075 ribulose-phosphate 3-epimerase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.26 GFF4283 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.76 GFF633 Ribulose-phosphate 3-epimerase (EC 5.1.3.1) low > 78
Pantoea sp. MT58 0.26 IAI47_14945 pyrroline-5-carboxylate reductase 0.76 IAI47_01910 ribulose-phosphate 3-epimerase — —
Synechocystis sp000284455 PCC 6803 0.25 SGL_RS17305 pyrroline-5-carboxylate reductase 0.46 SGL_RS09950 ribulose-phosphate 3-epimerase — —
Azospirillum sp. SherDot2 0.25 MPMX19_01399 Pyrroline-5-carboxylate reductase 0.56 MPMX19_02946 Ribulose-phosphate 3-epimerase — —
Agrobacterium fabrum C58 0.24 Atu2209 pyrroline-5-carboxylate reductase 0.45 Atu1839 ribulose-phosphate 3-epimerase — —
Desulfovibrio vulgaris Hildenborough JW710 0.24 DVU2332 proC pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.44 DVU2531 rpe ribulose-phosphate 3-epimerase (TIGR) — —
Sinorhizobium meliloti 1021 0.24 SMc02677 pyrroline-5-carboxylate reductase 0.44 SMc00511 D-ribulose-5-phosphate 3-epimerase low > 103
Rhodopseudomonas palustris CGA009 0.24 TX73_022630 pyrroline-5-carboxylate reductase 0.39 TX73_019755 ribulose-phosphate 3-epimerase — —
Erwinia tracheiphila SCR3 0.23 LU632_RS18995 proC pyrroline-5-carboxylate reductase 0.76 LU632_RS22850 rpe ribulose-phosphate 3-epimerase — —
Rhodospirillum rubrum S1H 0.23 Rru_A3281 Delta 1-pyrroline-5-carboxylate reductase (NCBI) 0.53 Rru_A2402 Ribulose-phosphate 3-epimerase (NCBI) — —
Azospirillum brasilense Sp245 0.23 AZOBR_RS06245 pyrroline-5-carboxylate reductase 0.45 AZOBR_RS06755 ribulose-phosphate 3-epimerase — —
Rhizobium sp. OAE497 0.23 ABIE40_RS13005 pyrroline-5-carboxylate reductase 0.44 ABIE40_RS10105 ribulose-phosphate 3-epimerase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.23 Echvi_2635 pyrroline-5-carboxylate reductase 0.41 Echvi_3575 ribulose-phosphate 3-epimerase 0.69 42
Xanthobacter sp. DMC5 0.22 GFF1925 Pyrroline-5-carboxylate reductase 0.57 GFF2441 Ribulose-phosphate 3-epimerase — —
Sphingomonas koreensis DSMZ 15582 0.22 Ga0059261_3321 pyrroline-5-carboxylate reductase 0.46 Ga0059261_2240 ribulose-phosphate 3-epimerase — —
Desulfovibrio vulgaris Miyazaki F 0.21 DvMF_3161 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.38 DvMF_0977 Ribulose-phosphate 3-epimerase (RefSeq) — —
Synechococcus elongatus PCC 7942 0.21 Synpcc7942_2058 proC pyrroline-5-carboxylate reductase 0.48 Synpcc7942_0604 rpe ribulose-phosphate 3-epimerase — —
Bacteroides ovatus ATCC 8483 0.21 BACOVA_03587 pyrroline-5-carboxylate reductase 0.40 BACOVA_01203 ribulose-phosphate 3-epimerase — —
Dinoroseobacter shibae DFL-12 0.20 Dshi_2645 pyrroline-5-carboxylate reductase (RefSeq) 0.41 Dshi_3006 Ribulose-phosphate 3-epimerase (RefSeq) — —
Caulobacter crescentus NA1000 0.20 CCNA_00528 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.44 CCNA_00100 Ribulose-5-phosphate 3-epimerase — —
Caulobacter crescentus NA1000 Δfur 0.20 CCNA_00528 pyrroline-5-carboxylate reductase 0.44 CCNA_00100 Ribulose-5-phosphate 3-epimerase — —
Bacteroides thetaiotaomicron VPI-5482 0.19 BT3757 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.40 BT3946 ribulose-phosphate 3-epimerase (NCBI ptt file) — —
Phaeobacter inhibens DSM 17395 0.19 PGA1_c24700 pyrroline-5-carboxylate reductase ProC 0.42 PGA1_c04170 ribulose-phosphate 3-epimerase Rpe — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.18 ABZR88_RS09865 pyrroline-5-carboxylate reductase 0.42 ABZR88_RS06500 ribulose-phosphate 3-epimerase — —
Bifidobacterium breve UCC2003 0.16 BBR_RS14625 pyrroline-5-carboxylate reductase 0.38 BBR_RS15800 ribulose-phosphate 3-epimerase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.16 CA264_07730 pyrroline-5-carboxylate reductase 0.42 CA264_21180 ribulose-phosphate 3-epimerase low > 74
Brevundimonas sp. GW460-12-10-14-LB2 0.16 A4249_RS09840 pyrroline-5-carboxylate reductase dimerization domain-containing protein 0.44 A4249_RS13160 ribulose-phosphate 3-epimerase — —
Mycobacterium tuberculosis H37Rv 0.16 Rv0500 Probable pyrroline-5-carboxylate reductase ProC (P5CR) (P5C reductase) 0.38 Rv1408 Probable ribulose-phosphate 3-epimerase Rpe (PPE) (R5P3E) (pentose-5-phosphate 3-epimerase) — —
Pedobacter sp. GW460-11-11-14-LB5 0.15 CA265_RS18505 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.43 CA265_RS08990 ribulose-phosphate 3-epimerase — —
Phocaeicola vulgatus CL09T03C04 0.15 HMPREF1058_RS08830 pyrroline-5-carboxylate reductase 0.42 HMPREF1058_RS07710 ribulose-phosphate 3-epimerase — —
Phocaeicola dorei CL03T12C01 0.15 ABI39_RS02960 pyrroline-5-carboxylate reductase 0.41 ABI39_RS00225 ribulose-phosphate 3-epimerase — —
Parabacteroides merdae CL09T00C40 0.15 HMPREF1078_RS10620 pyrroline-5-carboxylate reductase 0.39 HMPREF1078_RS00800 ribulose-phosphate 3-epimerase — —
Bacteroides stercoris CC31F 0.15 HMPREF1181_RS03440 pyrroline-5-carboxylate reductase 0.39 HMPREF1181_RS06505 ribulose-phosphate 3-epimerase low > 56
Cellulophaga baltica 18 0.14 M666_RS02635 pyrroline-5-carboxylate reductase 0.41 M666_RS08505 ribulose-phosphate 3-epimerase — —

Not shown: 1 genomes with orthologs for CSW01_02450 only; 3 genomes with orthologs for CSW01_13285 only