| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Pseudomonas simiae WCS417 | PS417_17535 | | beta-lactamase | insig. | 100 | 100 |
| o | Pseudomonas fluorescens SBW25 | PFLU_RS19340 | | MBL fold metallo-hydrolase | insig. | 92 | 100 |
| o | Pseudomonas fluorescens SBW25-INTG | PFLU_RS19340 | | MBL fold metallo-hydrolase | insig. | 92 | 100 |
| o | Pseudomonas orientalis W4I3 | QF045_RS19085 | | MBL fold metallo-hydrolase | insig. | 91 | 100 |
| o | Pseudomonas lactucae CFBP13502 | GEMAOFIL_03801 | | putative metallo-hydrolase | cofit | 90 | 100 |
| o | Pseudomonas fluorescens FW300-N2E3 | AO353_26625 | | MBL fold metallo-hydrolase | insig. | 82 | 100 |
| o | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_4482 | | FIG146518: Zn-dependent hydrolases, including glyoxylases | insig. | 82 | 100 |
| o | Pseudomonas fluorescens GW456-L13 | PfGW456L13_3538 | | FIG146518: Zn-dependent hydrolases, including glyoxylases | strong | 80 | 100 |
| o | Pseudomonas sp. DMC3 | GFF1610 | | putative metallo-hydrolase | cofit | 82 | 100 |
| o | Pseudomonas sp. RS175 | PFR28_02443 | | putative metallo-hydrolase | insig. | 80 | 100 |
| o | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_483 | | FIG146518: Zn-dependent hydrolases, including glyoxylases | insig. | 79 | 100 |
| o | Pseudomonas fluorescens FW300-N2C3 | AO356_23000 | | MBL fold metallo-hydrolase | insig. | 78 | 100 |
| o | Ralstonia sp. UNC404CL21Col | ABZR87_RS14030 | | MBL fold metallo-hydrolase | strong | 70 | 100 |
| o | Ralstonia solanacearum GMI1000 | RS_RS07750 | | MBL fold metallo-hydrolase | insig. | 69 | 100 |
| o | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS02055 | | MBL fold metallo-hydrolase | insig. | 68 | 100 |
| o | Ralstonia solanacearum UW163 | UW163_RS15380 | | MBL fold metallo-hydrolase | insig. | 68 | 100 |
| o | Ralstonia solanacearum PSI07 | RPSI07_RS15370 | | MBL fold metallo-hydrolase | insig. | 68 | 100 |
| o | Cupriavidus basilensis FW507-4G11 | RR42_RS35440 | | MBL fold metallo-hydrolase | insig. | 69 | 99 |
| o | Acidovorax sp. GW101-3H11 | Ac3H11_2265 | | FIG146518: Zn-dependent hydrolases, including glyoxylases | insig. | 68 | 100 |
| o | Pseudomonas aeruginosa PA14 | IKLFDK_14810 | | MBL fold metallo-hydrolase | sig. | 62 | 98 |
| o | Pseudomonas aeruginosa MRSN321 | DY961_RS02415 | | MBL fold metallo-hydrolase | insig. | 62 | 98 |
| o | Pseudomonas aeruginosa PUPa3 | DQ20_RS33175 | | MBL fold metallo-hydrolase | insig. | 62 | 98 |
| o | Variovorax sp. SCN45 | GFF6926 | | MBL-fold metallo-hydrolase superfamily | insig. | 61 | 99 |
| o | Herbaspirillum seropedicae SmR1 | HSERO_RS11580 | | beta-lactamase | insig. | 60 | 98 |
| o | Pseudomonas putida KT2440 | PP_0052 | | beta-lactamase domain protein, putative hydrolase | insig. | 59 | 99 |
| o | Pseudomonas sp. BP01 | JOY50_RS08320 | | MBL fold metallo-hydrolase | insig. | 59 | 99 |
| o | Marinobacter adhaerens HP15 | HP15_3977 | | metallo-beta-lactamase family protein | strong | 58 | 98 |
| o | Pseudomonas sp. SVBP6 | COO64_RS02145 | | MBL fold metallo-hydrolase | insig. | 57 | 99 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1531 | | FIG146518: Zn-dependent hydrolases, including glyoxylases | strong | 58 | 99 |
| o | Pseudomonas syringae pv. syringae B728a | Psyr_0078 | | Beta-lactamase-like protein | sig. | 58 | 99 |
| o | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_0078 | | Beta-lactamase-like protein | insig. | 58 | 99 |
| o | Castellaniella sp019104865 MT123 | ABCV34_RS06060 | | MBL fold metallo-hydrolase | insig. | 57 | 100 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_24320 | | MBL fold metallo-hydrolase | insig. | 56 | 99 |
| o | Sphingobium sp. HT1-2 | GFF5366 | | MBL-fold metallo-hydrolase superfamily | cofit | 59 | 98 |
| o | Pseudomonas stutzeri RCH2 | Psest_1789 | | Zn-dependent hydrolases, including glyoxylases | insig. | 56 | 100 |
| o | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS11565 | | MBL fold metallo-hydrolase | cofit | 58 | 99 |
| o | Rhodanobacter sp. FW510-T8 | OKGIIK_14260 | | MBL fold metallo-hydrolase | insig. | 56 | 99 |
| | Sphingobium sp. HT1-2 | GFF4418 | | MBL-fold metallo-hydrolase superfamily | cofit | 58 | 99 |
| o | Rhodanobacter denitrificans MT42 | LRK55_RS07460 | | MBL fold metallo-hydrolase | insig. | 56 | 98 |
| o | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS07730 | | MBL fold metallo-hydrolase | insig. | 56 | 98 |
| o | Phaeobacter inhibens DSM 17395 | PGA1_c12760 | | beta-lactamase hydrolase-like protein Blh | insig. | 55 | 100 |
| o | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS00780 | | MBL fold metallo-hydrolase | insig. | 54 | 98 |
| o | Acinetobacter radioresistens SK82 | MPMX26_03156 | | putative metallo-hydrolase | insig. | 52 | 99 |
| o | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF3377 | | SoxH protein, homolog | insig. | 54 | 99 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF3246 | | Zn-dependent hydrolases, including glyoxylases | insig. | 55 | 99 |
| o | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS15815 | | MBL fold metallo-hydrolase | insig. | 52 | 99 |
| o | Lysobacter sp. OAE881 | ABIE51_RS17110 | | MBL fold metallo-hydrolase | insig. | 52 | 100 |
| o | Sphingomonas koreensis DSMZ 15582 | Ga0059261_3084 | | Zn-dependent hydrolases, including glyoxylases | insig. | 53 | 98 |
| | Acinetobacter radioresistens SK82 | MPMX26_01992 | | putative metallo-hydrolase | sig. | 49 | 98 |
| o | Rhodopseudomonas palustris CGA009 | TX73_001890 | | MBL fold metallo-hydrolase | insig. | 52 | 98 |
| o | Dinoroseobacter shibae DFL-12 | Dshi_2517 | | beta-lactamase domain protein (RefSeq) | insig. | 51 | 99 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_0945 | | Zn-dependent hydrolases, including glyoxylases | insig. | 50 | 99 |
| o | Acinetobacter baumannii LAC-4 | RR41_RS13730 | | MBL fold metallo-hydrolase | insig. | 47 | 99 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS00230 | | MBL fold metallo-hydrolase | insig. | 50 | 99 |
| | Sinorhizobium meliloti 1021 | SMa1057 | | hypothetical protein | insig. | 48 | 99 |
| o | Caulobacter crescentus NA1000 | CCNA_02959 | | Zn-dependent hydrolase, glyoxalase II family | insig. | 51 | 98 |
| o | Caulobacter crescentus NA1000 Δfur | CCNA_02959 | | Zn-dependent hydrolase, glyoxalase II family | cofit | 51 | 98 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS11535 | | MBL fold metallo-hydrolase | insig. | 47 | 99 |
| | Sinorhizobium meliloti 1021 | SMc00276 | | hypothetical protein | insig. | 48 | 98 |
| | Marinobacter adhaerens HP15 | HP15_3732 | | metallo-beta-lactamase family protein | cofit | 47 | 99 |
| | Agrobacterium fabrum C58 | Atu3465 | | metallo-beta-lactamase superfamily protein | insig. | 47 | 99 |
| o | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.1151.1 | | Beta-lactamase | sig. | 50 | 93 |
| o | Kangiella aquimarina DSM 16071 | B158DRAFT_0351 | | Zn-dependent hydrolases, including glyoxylases | insig. | 43 | 99 |
| | Caulobacter crescentus NA1000 | CCNA_00483 | | Zn-dependent hydrolase, glyoxalase II family | cofit | 34 | 99 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_00483 | | Zn-dependent hydrolase, glyoxalase II family | cofit | 34 | 99 |
| | Caulobacter crescentus NA1000 | CCNA_03881 | | beta-lactamse domain-containing protein | insig. | 54 | 35 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_03881 | | beta-lactamse domain-containing protein | cofit | 54 | 35 |
| | Variovorax sp. SCN45 | GFF7988 | | MBL-fold metallo-hydrolase superfamily | no data | 43 | 52 |
| o | Synechocystis sp000284455 PCC 6803 | SGL_RS08475 | | MBL fold metallo-hydrolase | insig. | 30 | 92 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS20090 | | Zn-dependent hydrolase | insig. | 31 | 91 |
| o | Methylophilus sp. DMC18 | GFF1437 | | Beta-lactamase hydrolase-like protein | insig. | 29 | 83 |
| o | Synechococcus elongatus PCC 7942 | Synpcc7942_0937 | | hypothetical protein | insig. | 28 | 92 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF390 | | Rhodanese-related sulfurtransferase | insig. | 30 | 92 |
| | Acinetobacter baumannii LAC-4 | RR41_RS12780 | | MBL fold metallo-hydrolase | insig. | 27 | 93 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_06415 | | MBL fold metallo-hydrolase | insig. | 31 | 63 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02289 | | Glyoxylase, beta-lactamase superfamily II | insig. | 27 | 92 |
| | Pseudomonas putida KT2440 | PP_0772 | | Metallo-beta-lactamase family protein | insig. | 32 | 57 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS20840 | | beta-lactamase | insig. | 26 | 92 |
| | Pseudomonas stutzeri RCH2 | Psest_3219 | | Zn-dependent hydrolases, including glyoxylases | insig. | 30 | 61 |
| | Mycobacterium tuberculosis H37Rv | Rv0634c | | Possible glyoxalase II (hydroxyacylglutathione hydrolase) (GLX II) | insig. | 28 | 74 |
| | Dechlorosoma suillum PS | Dsui_0929 | | Zn-dependent hydrolase, glyoxylase | cofit | 30 | 78 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS31635 | | MBL fold metallo-hydrolase | insig. | 27 | 92 |
| | Pseudomonas sp. BP01 | JOY50_RS19395 | | MBL fold metallo-hydrolase | insig. | 31 | 57 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS19735 | | MBL fold hydrolase | insig. | 29 | 70 |
| | Pseudomonas sp. SVBP6 | COO64_RS03445 | | MBL fold metallo-hydrolase | insig. | 30 | 61 |
| | Marinobacter adhaerens HP15 | HP15_1191 | | metallo-beta-lactamase family protein | insig. | 32 | 64 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_18065 | | Hydroxyacylglutathione hydrolase GloC | insig. | 30 | 64 |
| | Rhodopseudomonas palustris CGA009 | TX73_002945 | | MBL fold metallo-hydrolase | insig. | 30 | 59 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_15160 | | MBL fold metallo-hydrolase | insig. | 33 | 56 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS06135 | | MBL fold metallo-hydrolase | cofit | 32 | 51 |
| | Pseudomonas sp. DMC3 | GFF4448 | | Hydroxyacylglutathione hydrolase GloC | insig. | 30 | 57 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS03825 | | MBL fold metallo-hydrolase | insig. | 29 | 64 |
| | Pseudomonas sp. S08-1 | OH686_06295 | | MBL-fold metallo-hydrolase superfamily | insig. | 28 | 61 |
| | Shewanella oneidensis MR-1 | SO2563 | | metallo-beta-lactamase family protein (NCBI ptt file) | sig. | 32 | 55 |
| | Pseudomonas segetis P6 | ACVTMO_RS18280 | | MBL fold metallo-hydrolase | insig. | 29 | 60 |
| | Paraburkholderia graminis OAS925 | ABIE53_000373 | | sulfur dioxygenase | insig. | 26 | 92 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS15120 | | MBL fold metallo-hydrolase | insig. | 32 | 55 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_2759 | | hydroxyacylglutathione hydrolase | strong | 31 | 63 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_01115 | | Hydroxyacylglutathione hydrolase GloC | cofit | 33 | 56 |
| | Xanthobacter sp. DMC5 | GFF3817 | | Hydroxyacylglutathione hydrolase GloC | insig. | 28 | 62 |