Homologs of BWI76_RS22705 from Klebsiella michiganensis M5al

siroheme synthase
SEED: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)

Top 100 hits from BLASTp (E < 0.01)

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Orth Species Gene Name Description Fitness %Id Cov
  Klebsiella michiganensis M5al BWI76_RS22705 siroheme synthase sig. 100 100
o Enterobacter asburiae PDN3 EX28DRAFT_2849 uroporphyrin-III C-methyltransferase strong 70 100
o Enterobacter sp. TBS_079 MPMX20_03639 Siroheme synthase insig. 69 100
o Pantoea sp. MT58 IAI47_04175 uroporphyrinogen-III C-methyltransferase strong 66 100
o Pectobacterium carotovorum WPP14 HER17_RS04280 siroheme synthase CysG cofit 63 100
o Erwinia tracheiphila SCR3 LU632_RS06420 cysG siroheme synthase CysG strong 63 100
o Serratia liquefaciens MT49 IAI46_03710 uroporphyrinogen-III C-methyltransferase cofit 65 100
o Rahnella sp. WP5 EX31_RS07885 uroporphyrinogen-III C-methyltransferase cofit 65 100
o Erwinia amylovora T8 OLJFJH_09320 siroheme synthase CysG strong 63 100
o Dickeya dadantii 3937 DDA3937_RS16930 uroporphyrinogen-III C-methyltransferase strong 64 100
o Dickeya dianthicola ME23 DZA65_RS18075 uroporphyrinogen-III C-methyltransferase strong 63 100
o Dickeya dianthicola 67-19 HGI48_RS17000 uroporphyrinogen-III C-methyltransferase cofit 63 100
  Enterobacter asburiae PDN3 EX28DRAFT_4160 uroporphyrin-III C-methyltransferase insig. 51 97
  Escherichia coli BL21 ECD_03219 fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase strong 50 97
  Escherichia coli HS(pFamp)R (ATCC 700891) OHPLBJKB_00334 Siroheme synthase insig. 50 97
  Escherichia coli BW25113 b3368 cysG fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) strong 50 97
  Escherichia fergusonii Becca EFB2_00454 Siroheme synthase insig. 50 97
  Escherichia coli Nissle 1917 ECOLIN_RS19285 siroheme synthase CysG cofit 50 97
  Escherichia coli ECOR27 NOLOHH_08980 cysG siroheme synthase CysG strong 50 97
  Escherichia coli ECRC62 BNILDI_02540 cysG siroheme synthase CysG strong 50 97
  Escherichia coli ECRC100 OKFHMN_17180 cysG siroheme synthase CysG strong 50 97
  Escherichia coli ECRC101 MCAODC_07710 cysG siroheme synthase CysG strong 50 97
  Escherichia coli ECRC102 NIAGMN_14950 cysG siroheme synthase CysG strong 50 97
  Escherichia coli ECRC98 JDDGAC_20810 cysG siroheme synthase CysG strong 50 97
  Escherichia coli ECRC99 KEDOAH_10960 cysG siroheme synthase CysG no data 50 97
  Rahnella sp. WP5 EX31_RS04680 uroporphyrinogen-III C-methyltransferase insig. 50 96
  Escherichia coli ECOR38 HEPCGN_16010 cysG siroheme synthase CysG strong 50 97
  Serratia liquefaciens MT49 IAI46_23670 uroporphyrinogen-III C-methyltransferase insig. 50 98
  Pseudomonas fluorescens FW300-N2E2 Pf6N2E2_302 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) strong 52 97
  Enterobacter sp. TBS_079 MPMX20_04271 Siroheme synthase sig. 50 97
  Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 GFF3700 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) insig. 49 97
  Pseudomonas sp. RS175 PFR28_02603 Siroheme synthase strong 51 97
  Pseudomonas fluorescens FW300-N2C3 AO356_22200 sirohydrochlorin ferrochelatase strong 51 97
  Pseudomonas stutzeri RCH2 Psest_2037 uroporphyrin-III C-methyltransferase strong 50 98
  Pseudomonas fluorescens FW300-N2E3 AO353_27625 sirohydrochlorin ferrochelatase no data 51 97
  Pseudomonas sp. DMC3 GFF1535 Siroheme synthase strong 51 97
  Pseudomonas fluorescens GW456-L13 PfGW456L13_2656 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) strong 51 97
  Pseudomonas aeruginosa PA14 IKLFDK_13105 siroheme synthase CysG strong 51 97
  Klebsiella michiganensis M5al BWI76_RS26055 siroheme synthase strong 49 97
  Pseudomonas fluorescens FW300-N1B4 Pf1N1B4_4065 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) strong 50 97
  Pseudomonas sp. SVBP6 COO64_RS24155 cysG siroheme synthase CysG strong 50 97
  Pseudomonas simiae WCS417 PS417_16465 sirohydrochlorin ferrochelatase strong 50 97
  Pseudomonas fluorescens SBW25 PFLU_RS18505 uroporphyrinogen-III C-methyltransferase strong 50 97
  Pseudomonas fluorescens SBW25-INTG PFLU_RS18505 uroporphyrinogen-III C-methyltransferase strong 50 97
  Pectobacterium carotovorum WPP14 HER17_RS01835 siroheme synthase CysG insig. 49 96
  Pseudomonas syringae pv. syringae B728a Psyr_3174 uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase strong 49 98
  Pseudomonas syringae pv. syringae B728a ΔmexB Psyr_3174 uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase cofit 49 98
  Methylophilus sp. DMC18 GFF2711 Siroheme synthase no data 49 96
  Alteromonas macleodii MIT1002 MIT1002_00665 Siroheme synthase no data 46 97
  Pseudomonas sp. BP01 JOY50_RS06510 cysG siroheme synthase CysG strong 50 98
  Pseudomonas putida KT2440 PP_3999 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase strong 50 98
  Pseudomonas sp. S08-1 OH686_00285 Precorrin-2 oxidase or Sirohydrochlorin ferrochelatase activity of CysG / Uroporphyrinogen-III methyltransferase strong 51 96
  Kangiella aquimarina DSM 16071 B158DRAFT_2163 uroporphyrin-III C-methyltransferase insig. 47 96
  Acinetobacter radioresistens SK82 MPMX26_00706 Siroheme synthase no data 45 96
  Rhodanobacter sp000427505 FW510-R12 LRK53_RS09200 siroheme synthase CysG strong 49 96
  Rhodanobacter sp. FW510-T8 OKGIIK_05980 cysG siroheme synthase CysG insig. 49 96
  Dyella japonica UNC79MFTsu3.2 ABZR86_RS05880 siroheme synthase CysG strong 47 96
  Castellaniella sp019104865 MT123 ABCV34_RS00210 siroheme synthase CysG strong 43 97
  Lysobacter sp. OAE881 ABIE51_RS15855 siroheme synthase CysG strong 46 96
  Rhodanobacter denitrificans FW104-10B01 LRK54_RS00910 siroheme synthase CysG cofit 47 96
  Rhodanobacter denitrificans MT42 LRK55_RS00685 siroheme synthase CysG insig. 47 96
o Rhodopseudomonas palustris CGA009 TX73_021850 siroheme synthase CysG cofit 40 97
  Dyella japonica UNC79MFTsu3.2 ABZR86_RS03870 siroheme synthase CysG insig. 44 96
o Agrobacterium fabrum C58 Atu1454 siroheme synthase strong 40 94
  Agrobacterium fabrum C58 Atu3899 siroheme synthase insig. 39 93
  Sinorhizobium meliloti 1021 SMc01053 siroheme synthase strong 38 94
o Rhizobium sp. OAE497 ABIE40_RS09140 siroheme synthase CysG strong 39 94
o Dinoroseobacter shibae DFL-12 Dshi_1671 uroporphyrin-III C-methyltransferase (RefSeq) insig. 42 87
  Brevundimonas sp. GW460-12-10-14-LB2 A4249_RS09675 siroheme synthase CysG strong 42 91
o Bosea sp. OAE506 ABIE41_RS15910 siroheme synthase CysG no data 40 96
o Xanthobacter sp. DMC5 GFF1971 Siroheme synthase no data 38 90
  Shewanella sp. ANA-3 Shewana3_0862 uroporphyrinogen-III C-methyltransferase (RefSeq) strong 54 54
  Shewanella amazonensis SB2B Sama_2892 uroporphyrin-III C-methyltransferase (RefSeq) strong 52 56
  Shewanella loihica PV-4 Shew_0672 uroporphyrin-III C-methyltransferase (RefSeq) cofit 53 54
  Vibrio cholerae E7946 ATCC 55056 CSW01_12965 uroporphyrinogen-III C-methyltransferase insig. 58 54
  Shewanella oneidensis MR-1 SO3728 cobA uroporphyrin-III C-methyltransferase (NCBI ptt file) strong 53 54
  Rhodospirillum rubrum S1H Rru_A1933 Uroporphyrin-III C-methyltransferase (NCBI) sig. 44 80
  Dinoroseobacter shibae DFL-12 Dshi_1155 uroporphyrin-III C-methyltransferase (RefSeq) no data 38 94
  Marinobacter adhaerens HP15 HP15_1815 siroheme synthase strong 50 52
  Pseudomonas aeruginosa PA14 IKLFDK_22885 uroporphyrinogen-III C-methyltransferase insig. 56 49
  Pseudomonas fluorescens FW300-N2E2 Pf6N2E2_696 Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) insig. 54 52
  Pseudomonas fluorescens FW300-N2C3 AO356_25030 uroporphyrin-III methyltransferase insig. 54 52
  Pseudomonas fluorescens FW300-N2E3 AO353_21925 uroporphyrin-III methyltransferase insig. 53 50
  Pseudomonas sp. RS175 PFR28_02239 Siroheme synthase insig. 51 55
  Pseudomonas stutzeri RCH2 Psest_0810 uroporphyrin-III C-methyltransferase strong 55 50
  Pectobacterium carotovorum WPP14 HER17_RS07340 uroporphyrinogen-III C-methyltransferase insig. 53 51
  Xanthomonas campestris pv. campestris strain 8004 Xcc-8004.1248.1 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) strong 51 51
  Pseudomonas fluorescens FW300-N1B4 Pf1N1B4_5773 Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) no data 52 50
  Pseudomonas sp. SVBP6 COO64_RS14065 cobA uroporphyrinogen-III C-methyltransferase insig. 54 50
  Pantoea sp. MT58 IAI47_11160 uroporphyrinogen-III C-methyltransferase strong 52 52
  Dechlorosoma suillum PS Dsui_3319 uroporphyrin-III C-methyltransferase strong 49 55
  Rahnella sp. WP5 EX31_RS09100 uroporphyrinogen-III C-methyltransferase insig. 51 51
  Dickeya dianthicola ME23 DZA65_RS14740 uroporphyrinogen-III C-methyltransferase insig. 51 49
  Dickeya dianthicola 67-19 HGI48_RS14080 uroporphyrinogen-III C-methyltransferase insig. 49 53
  Desulfovibrio vulgaris Hildenborough JW710 DVU0734 cysG-1 uroporphyrinogen III synthase/methyltransferase (TIGR) no data 47 51
  Dickeya dadantii 3937 DDA3937_RS14080 uroporphyrinogen-III C-methyltransferase sig. 50 49
  Desulfovibrio vulgaris Miyazaki F DvMF_2767 uroporphyrin-III C-methyltransferase (RefSeq) no data 48 51
  Dechlorosoma suillum PS Dsui_2969 uroporphyrin-III C-methyltransferase cofit 49 50
  Magnetospirillum magneticum AMB-1 AMB_RS17015 uroporphyrinogen-III C-methyltransferase no data 46 52
  Castellaniella sp019104865 MT123 ABCV34_RS06895 uroporphyrinogen-III C-methyltransferase insig. 49 50