| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3700 | | Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) | insig. | 100 | 100 |
| o | Escherichia coli ECOR38 | HEPCGN_16010 | cysG | siroheme synthase CysG | strong | 91 | 100 |
| o | Escherichia coli ECRC100 | OKFHMN_17180 | cysG | siroheme synthase CysG | strong | 90 | 100 |
| o | Escherichia coli ECRC101 | MCAODC_07710 | cysG | siroheme synthase CysG | strong | 90 | 100 |
| o | Escherichia coli ECRC102 | NIAGMN_14950 | cysG | siroheme synthase CysG | strong | 90 | 100 |
| o | Escherichia coli ECRC98 | JDDGAC_20810 | cysG | siroheme synthase CysG | strong | 90 | 100 |
| o | Escherichia coli ECRC99 | KEDOAH_10960 | cysG | siroheme synthase CysG | no data | 90 | 100 |
| o | Escherichia fergusonii Becca | EFB2_00454 | | Siroheme synthase | insig. | 90 | 100 |
| o | Escherichia coli Nissle 1917 | ECOLIN_RS19285 | | siroheme synthase CysG | cofit | 90 | 100 |
| o | Escherichia coli BL21 | ECD_03219 | | fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase | strong | 90 | 100 |
| o | Escherichia coli ECOR27 | NOLOHH_08980 | cysG | siroheme synthase CysG | strong | 90 | 100 |
| o | Escherichia coli ECRC62 | BNILDI_02540 | cysG | siroheme synthase CysG | strong | 90 | 100 |
| o | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_00334 | | Siroheme synthase | insig. | 90 | 100 |
| o | Escherichia coli BW25113 | b3368 | cysG | fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) | strong | 90 | 100 |
| o | Enterobacter asburiae PDN3 | EX28DRAFT_4160 | | uroporphyrin-III C-methyltransferase | insig. | 89 | 100 |
| o | Enterobacter sp. TBS_079 | MPMX20_04271 | | Siroheme synthase | sig. | 89 | 100 |
| o | Klebsiella michiganensis M5al | BWI76_RS26055 | | siroheme synthase | strong | 86 | 100 |
| o | Klebsiella pneumoniae MKP103 | KDGMDA_06880 | | siroheme synthase CysG | insig. | 85 | 100 |
| o | Klebsiella pneumoniae MRSN742743 | GJGHJB_00360 | cysG | siroheme synthase CysG | sig. | 85 | 100 |
| o | Pectobacterium carotovorum WPP14 | HER17_RS01835 | | siroheme synthase CysG | insig. | 71 | 100 |
| o | Rahnella sp. WP5 | EX31_RS04680 | | uroporphyrinogen-III C-methyltransferase | insig. | 71 | 100 |
| o | Serratia liquefaciens MT49 | IAI46_23670 | | uroporphyrinogen-III C-methyltransferase | insig. | 72 | 100 |
| o | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13516_RS01925 | cysG | siroheme synthase CysG | cofit | 69 | 99 |
| o | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_17440 | cysG | siroheme synthase CysG | strong | 54 | 100 |
| o | Erwinia tracheiphila SCR3 | LU632_RS06420 | cysG | siroheme synthase CysG | strong | 54 | 100 |
| o | Pseudomonas stutzeri RCH2 | Psest_2037 | | uroporphyrin-III C-methyltransferase | strong | 54 | 100 |
| | Pectobacterium carotovorum WPP14 | HER17_RS04280 | | siroheme synthase CysG | cofit | 53 | 100 |
| o | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_4065 | | Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) | strong | 55 | 100 |
| | Serratia liquefaciens MT49 | IAI46_03710 | | uroporphyrinogen-III C-methyltransferase | cofit | 54 | 100 |
| o | Pseudomonas protegens RBAN4 | FABNJH_20035 | cysG | siroheme synthase CysG | strong | 54 | 100 |
| o | Erwinia amylovora T8 | OLJFJH_09320 | | siroheme synthase CysG | strong | 53 | 100 |
| o | Pseudomonas syringae pv. syringae B728a | Psyr_3174 | | uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase | strong | 53 | 100 |
| o | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_3174 | | uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase | cofit | 53 | 100 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_2849 | | uroporphyrin-III C-methyltransferase | strong | 51 | 100 |
| | Enterobacter sp. TBS_079 | MPMX20_03639 | | Siroheme synthase | insig. | 51 | 100 |
| o | Pseudomonas sp. DMC3 | GFF1535 | | Siroheme synthase | strong | 54 | 100 |
| o | Dickeya dianthicola 67-19 | HGI48_RS17000 | | uroporphyrinogen-III C-methyltransferase | cofit | 54 | 100 |
| o | Pseudomonas aeruginosa MRSN321 | PFGADD_02409 | cysG | siroheme synthase CysG | strong | 54 | 100 |
| o | Pseudomonas orientalis W4I3 | QF045_RS18220 | | siroheme synthase CysG | strong | 53 | 100 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13516_RS04445 | cysG | siroheme synthase CysG | strong | 52 | 100 |
| o | Dickeya dianthicola ME23 | DZA65_RS18075 | | uroporphyrinogen-III C-methyltransferase | strong | 54 | 100 |
| o | Pseudomonas fluorescens GW456-L13 | PfGW456L13_2656 | | Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) | strong | 54 | 100 |
| o | Dickeya dadantii 3937 | DDA3937_RS16930 | | uroporphyrinogen-III C-methyltransferase | strong | 54 | 100 |
| o | Kangiella aquimarina DSM 16071 | B158DRAFT_2163 | | uroporphyrin-III C-methyltransferase | insig. | 50 | 100 |
| o | Pantoea sp. MT58 | IAI47_04175 | | uroporphyrinogen-III C-methyltransferase | strong | 52 | 100 |
| o | Pseudomonas aeruginosa PA14 | IKLFDK_13105 | | siroheme synthase CysG | strong | 54 | 100 |
| | Rahnella sp. WP5 | EX31_RS07885 | | uroporphyrinogen-III C-methyltransferase | cofit | 54 | 100 |
| o | Pseudomonas sp. RS175 | PFR28_02603 | | Siroheme synthase | strong | 53 | 100 |
| o | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_302 | | Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) | strong | 53 | 100 |
| o | Pseudomonas simiae WCS417 | PS417_16465 | | sirohydrochlorin ferrochelatase | strong | 52 | 100 |
| o | Pseudomonas aeruginosa PUPa3 | NPBIFN_02448 | cysG | siroheme synthase CysG | strong | 53 | 100 |
| o | Pseudomonas fluorescens SBW25 | PFLU_RS18505 | | uroporphyrinogen-III C-methyltransferase | strong | 52 | 100 |
| o | Pseudomonas fluorescens SBW25-INTG | PFLU_RS18505 | | uroporphyrinogen-III C-methyltransferase | strong | 52 | 100 |
| o | Pseudomonas fluorescens FW300-N2C3 | AO356_22200 | | sirohydrochlorin ferrochelatase | strong | 52 | 100 |
| o | Pseudomonas lactucae CFBP13502 | GEMAOFIL_03620 | | Siroheme synthase | strong | 52 | 100 |
| o | Pseudomonas fluorescens FW300-N2E3 | AO353_27625 | | sirohydrochlorin ferrochelatase | no data | 53 | 99 |
| o | Pseudomonas sp. SVBP6 | COO64_RS24155 | cysG | siroheme synthase CysG | strong | 53 | 100 |
| o | Pseudomonas segetis P6 | ACVTMO_RS12565 | cysG | siroheme synthase CysG | no data | 52 | 100 |
| o | Methylophilus sp. DMC18 | GFF2711 | | Siroheme synthase | no data | 49 | 99 |
| o | Pseudomonas sp. BP01 | JOY50_RS06510 | cysG | siroheme synthase CysG | strong | 52 | 100 |
| o | Pseudomonas putida KT2440 | PP_3999 | | Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase | strong | 52 | 100 |
| | Klebsiella michiganensis M5al | BWI76_RS22705 | | siroheme synthase | sig. | 49 | 100 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_03280 | | siroheme synthase CysG | insig. | 50 | 100 |
| o | Acinetobacter baumannii LAC-4 | RR41_RS03950 | | siroheme synthase CysG | sig. | 50 | 99 |
| | Klebsiella pneumoniae MRSN742743 | GJGHJB_00997 | cysG | siroheme synthase CysG | insig. | 50 | 100 |
| o | Alteromonas macleodii MIT1002 | MIT1002_00665 | | Siroheme synthase | no data | 48 | 99 |
| o | Acinetobacter radioresistens SK82 | MPMX26_00706 | | Siroheme synthase | no data | 50 | 99 |
| o | Pseudomonas sp. S08-1 | OH686_00285 | | Precorrin-2 oxidase or Sirohydrochlorin ferrochelatase activity of CysG / Uroporphyrinogen-III methyltransferase | strong | 53 | 100 |
| o | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS05880 | | siroheme synthase CysG | strong | 52 | 98 |
| o | Lysobacter sp. OAE881 | ABIE51_RS15855 | | siroheme synthase CysG | strong | 51 | 99 |
| o | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS09200 | | siroheme synthase CysG | strong | 49 | 98 |
| o | Castellaniella sp019104865 MT123 | ABCV34_RS00210 | | siroheme synthase CysG | strong | 45 | 99 |
| o | Rhodanobacter sp. FW510-T8 | OKGIIK_05980 | cysG | siroheme synthase CysG | strong | 49 | 98 |
| o | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS00910 | | siroheme synthase CysG | cofit | 49 | 98 |
| o | Rhodanobacter denitrificans MT42 | LRK55_RS00685 | | siroheme synthase CysG | insig. | 49 | 98 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS03870 | | siroheme synthase CysG | insig. | 43 | 99 |
| o | Agrobacterium fabrum C58 | Atu3899 | | siroheme synthase | insig. | 41 | 96 |
| o | Sinorhizobium meliloti 1021 | SMc01053 | | siroheme synthase | strong | 39 | 97 |
| | Agrobacterium fabrum C58 | Atu1454 | | siroheme synthase | strong | 37 | 97 |
| o | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS09675 | | siroheme synthase CysG | strong | 44 | 95 |
| o | Rhizobium sp. OAE497 | ABIE40_RS09140 | | siroheme synthase CysG | strong | 38 | 97 |
| o | Rhodopseudomonas palustris CGA009 | TX73_021850 | | siroheme synthase CysG | cofit | 38 | 97 |
| | Marinobacter adhaerens HP15 | HP15_1815 | | siroheme synthase | strong | 57 | 54 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_12965 | | uroporphyrinogen-III C-methyltransferase | insig. | 63 | 53 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_22885 | | uroporphyrinogen-III C-methyltransferase | insig. | 58 | 51 |
| | Pseudomonas aeruginosa MRSN321 | PFGADD_00519 | | uroporphyrinogen-III C-methyltransferase | insig. | 58 | 51 |
| | Pseudomonas aeruginosa PUPa3 | NPBIFN_00522 | | uroporphyrinogen-III C-methyltransferase | insig. | 58 | 51 |
| | Shewanella loihica PV-4 | Shew_0672 | | uroporphyrin-III C-methyltransferase (RefSeq) | cofit | 54 | 55 |
| | Dickeya dianthicola ME23 | DZA65_RS14740 | | uroporphyrinogen-III C-methyltransferase | insig. | 58 | 50 |
| | Dickeya dadantii 3937 | DDA3937_RS14080 | | uroporphyrinogen-III C-methyltransferase | sig. | 58 | 50 |
| | Pseudomonas stutzeri RCH2 | Psest_0810 | | uroporphyrin-III C-methyltransferase | strong | 58 | 51 |
| | Shewanella sp. ANA-3 | Shewana3_0862 | | uroporphyrinogen-III C-methyltransferase (RefSeq) | strong | 56 | 53 |
| | Dickeya dianthicola 67-19 | HGI48_RS14080 | | uroporphyrinogen-III C-methyltransferase | insig. | 58 | 50 |
| | Pseudomonas sp. SVBP6 | COO64_RS14065 | cobA | uroporphyrinogen-III C-methyltransferase | insig. | 56 | 51 |
| | Pseudomonas sp. RS175 | PFR28_02239 | | Siroheme synthase | insig. | 58 | 51 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_25030 | | uroporphyrin-III methyltransferase | insig. | 56 | 51 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_696 | | Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) | insig. | 56 | 51 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_03459 | | Siroheme synthase | cofit | 55 | 51 |
| | Shewanella amazonensis SB2B | Sama_2892 | | uroporphyrin-III C-methyltransferase (RefSeq) | strong | 56 | 53 |
| | Shewanella oneidensis MR-1 | SO3728 | cobA | uroporphyrin-III C-methyltransferase (NCBI ptt file) | strong | 54 | 53 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_21925 | | uroporphyrin-III methyltransferase | insig. | 56 | 51 |
| o | Dinoroseobacter shibae DFL-12 | Dshi_1155 | | uroporphyrin-III C-methyltransferase (RefSeq) | no data | 37 | 100 |
| o | Xanthobacter sp. DMC5 | GFF1971 | | Siroheme synthase | no data | 35 | 97 |
| | Pectobacterium carotovorum WPP14 | HER17_RS07340 | | uroporphyrinogen-III C-methyltransferase | insig. | 57 | 50 |
| o | Rhodospirillum rubrum S1H | Rru_A1933 | | Uroporphyrin-III C-methyltransferase (NCBI) | sig. | 42 | 82 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS17015 | | uroporphyrinogen-III C-methyltransferase | no data | 53 | 53 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.1248.1 | | Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) | strong | 56 | 52 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_5773 | | Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) | no data | 56 | 51 |
| | Bosea sp. OAE506 | ABIE41_RS15910 | | siroheme synthase CysG | no data | 39 | 76 |
| | Rahnella sp. WP5 | EX31_RS09100 | | uroporphyrinogen-III C-methyltransferase | insig. | 56 | 51 |
| | Dinoroseobacter shibae DFL-12 | Dshi_1671 | | uroporphyrin-III C-methyltransferase (RefSeq) | insig. | 38 | 89 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0734 | cysG-1 | uroporphyrinogen III synthase/methyltransferase (TIGR) | no data | 49 | 53 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS07085 | | uroporphyrinogen-III C-methyltransferase | insig. | 56 | 51 |
| | Pantoea sp. MT58 | IAI47_11160 | | uroporphyrinogen-III C-methyltransferase | strong | 56 | 51 |
| | Castellaniella sp019104865 MT123 | ABCV34_RS06895 | | uroporphyrinogen-III C-methyltransferase | insig. | 52 | 51 |
| | Dechlorosoma suillum PS | Dsui_3319 | | uroporphyrin-III C-methyltransferase | strong | 52 | 53 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2767 | | uroporphyrin-III C-methyltransferase (RefSeq) | no data | 47 | 52 |
| | Dechlorosoma suillum PS | Dsui_2969 | | uroporphyrin-III C-methyltransferase | cofit | 49 | 53 |
| | Fusobacterium nucleatum SB010 | HUW76_06215 | | uroporphyrinogen-III C-methyltransferase | cofit | 43 | 53 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1496 | | uroporphyrin-III C-methyltransferase | strong | 46 | 53 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_2610 | cobA | uroporphyrin-III C-methyltransferase | no data | 47 | 52 |
| | Dinoroseobacter shibae DFL-12 | Dshi_3179 | | uroporphyrin-III C-methyltransferase (RefSeq) | insig. | 50 | 51 |
| | Rhizobium sp. OAE497 | ABIE40_RS11110 | | uroporphyrinogen-III C-methyltransferase | insig. | 45 | 53 |
| | Azospirillum sp. SherDot2 | MPMX19_05563 | | Uroporphyrinogen-III C-methyltransferase | no data | 49 | 52 |
| | Sinorhizobium meliloti 1021 | SMc04284 | | uroporphyrin-III C-methyltransferase | no data | 45 | 52 |
| | Caulobacter crescentus NA1000 | CCNA_01175 | | uroporphyrin-III C-methyltransferase | strong | 49 | 51 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_01175 | | uroporphyrin-III C-methyltransferase | cofit | 49 | 51 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS14480 | | uroporphyrinogen-III C-methyltransferase | no data | 47 | 50 |
| | Sphingobium sp. HT1-2 | GFF1450 | | Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) | no data | 48 | 52 |
| | Agrobacterium fabrum C58 | Atu2794 | | uroporphyrin-III C-methyltransferase | insig. | 45 | 53 |
| | Methylophilus sp. DMC18 | GFF206 | | Siroheme synthase | cofit | 44 | 53 |
| | Dinoroseobacter shibae DFL-12 | Dshi_1692 | | uroporphyrin-III C-methyltransferase (RefSeq) | no data | 46 | 55 |
| | Rhodospirillum rubrum S1H | Rru_A3362 | | Uroporphyrin-III C-methyltransferase-like (NCBI) | sig. | 45 | 54 |
| | Azospirillum sp. SherDot2 | MPMX19_05929 | | Siroheme synthase | insig. | 42 | 59 |
| | Mycobacterium tuberculosis H37Rv | Rv2847c | | Possible multifunctional enzyme siroheme synthase CysG: uroporphyrin-III C-methyltransferase (urogen III methylase) (SUMT) (uroporphyrinogen III methylase) (UROM) + precorrin-2 oxidase + ferrochelatase | no data | 32 | 93 |
| | Alteromonas macleodii MIT1002 | MIT1002_00701 | | Siroheme synthase | insig. | 46 | 52 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_06527 | | uroporphyrin-III C-methyltransferase | insig. | 47 | 49 |
| | Azospirillum brasilense Sp245 | AZOBR_RS10135 | | uroporphyrin-III methyltransferase | insig. | 47 | 52 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF3661 | | Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) | insig. | 48 | 50 |
| | Variovorax sp. OAS795 | ABID97_RS16030 | | uroporphyrinogen-III C-methyltransferase | insig. | 46 | 50 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS24835 | | uroporphyrin-III methyltransferase | insig. | 47 | 50 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS08705 | | uroporphyrinogen-III C-methyltransferase | insig. | 44 | 50 |
| | Methanococcus maripaludis JJ | MMJJ_RS00130 | | uroporphyrinogen-III C-methyltransferase | no data | 43 | 50 |
| | Azospirillum brasilense Sp245 | AZOBR_RS18580 | | uroporphyrin-III methyltransferase | no data | 45 | 49 |
| | Variovorax sp. OAS795 | ABID97_RS20615 | | uroporphyrinogen-III C-methyltransferase | strong | 46 | 50 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3241 | | Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) | strong | 45 | 52 |
| | Methanococcus maripaludis S2 | MMP_RS05005 | | uroporphyrinogen-III C-methyltransferase | no data | 43 | 50 |
| | Paraburkholderia graminis OAS925 | ABIE53_006182 | | uroporphyrin-III C-methyltransferase | sig. | 45 | 50 |
| | Pseudomonas sp. S08-1 | OH686_00495 | | Uroporphyrinogen-III methyltransferase | strong | 47 | 50 |
| | Pseudomonas aeruginosa MRSN321 | PFGADD_03356 | cobA | Uroporphyrinogen-III C-methyltransferase | sig. | 46 | 50 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_08595 | | Uroporphyrinogen-III C-methyltransferase | sig. | 46 | 50 |
| | Pseudomonas aeruginosa PUPa3 | NPBIFN_03392 | cobA | Uroporphyrinogen-III C-methyltransferase | strong | 46 | 50 |
| | Variovorax sp. SCN45 | GFF4724 | | Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) | strong | 47 | 50 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_00820 | | uroporphyrin-III methyltransferase | sig. | 46 | 50 |
| | Pseudomonas sp. SVBP6 | COO64_RS05330 | cobA | uroporphyrinogen-III C-methyltransferase | insig. | 47 | 50 |
| | Pseudomonas sp. DMC3 | GFF5244 | | Uroporphyrinogen-III C-methyltransferase | cofit | 45 | 51 |
| | Castellaniella sp019104865 MT123 | ABCV34_RS06900 | | NAD(P)-dependent oxidoreductase | insig. | 40 | 56 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS04100 | | uroporphyrinogen-III C-methyltransferase | strong | 42 | 52 |
| | Pseudomonas segetis P6 | ACVTMO_RS12975 | cobA | uroporphyrinogen-III C-methyltransferase | insig. | 45 | 50 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_04341 | | Uroporphyrinogen-III C-methyltransferase | cofit | 44 | 50 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_4104 | | Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) | sig. | 44 | 52 |
| | Pseudomonas orientalis W4I3 | QF045_RS22805 | | uroporphyrinogen-III C-methyltransferase | cofit | 44 | 50 |
| | Pseudomonas simiae WCS417 | PS417_20980 | | uroporphyrin-III methyltransferase | strong | 44 | 50 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_2381 | | Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) | sig. | 44 | 49 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS22590 | | uroporphyrinogen-III C-methyltransferase | insig. | 44 | 50 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS22590 | | uroporphyrinogen-III C-methyltransferase | strong | 44 | 50 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_2098 | | uroporphyrinogen-III C-methyltransferase | insig. | 43 | 51 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_2098 | | uroporphyrinogen-III C-methyltransferase | insig. | 43 | 51 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS13600 | | uroporphyrinogen-III C-methyltransferase | insig. | 43 | 50 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2716.1 | | Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) | strong | 36 | 72 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_02785 | | uroporphyrin-III methyltransferase | insig. | 44 | 49 |
| | Pseudomonas sp. RS175 | PFR28_01046 | | Uroporphyrinogen-III C-methyltransferase | insig. | 44 | 50 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_3834 | | Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) | cofit | 44 | 50 |
| | Sinorhizobium meliloti 1021 | SM_b20987 | | siroheme synthase | insig. | 33 | 76 |
| | Pseudomonas protegens RBAN4 | FABNJH_09705 | cobA | uroporphyrinogen-III C-methyltransferase | insig. | 44 | 49 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS02650 | | uroporphyrinogen-III C-methyltransferase | cofit | 45 | 53 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_0271 | cobA | uroporphyrinogen-III C-methyltransferase | no data | 40 | 51 |
| | Pseudomonas putida KT2440 | PP_2090 | | Uroporphyrinogen-III C-methyltransferase | sig. | 44 | 50 |
| | Pseudomonas sp. BP01 | JOY50_RS22130 | cobA | uroporphyrinogen-III C-methyltransferase | insig. | 43 | 50 |
| | Pseudomonas stutzeri RCH2 | Psest_1925 | | uroporphyrin-III C-methyltransferase | strong | 42 | 50 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_02520 | | uroporphyrinogen-III C-methyltransferase | strong | 40 | 52 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS16905 | | uroporphyrinogen-III C-methyltransferase | no data | 39 | 51 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_1902 | | uroporphyrin-III C-methyltransferase | insig. | 40 | 51 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c20740 | | uroporphyrinogen-III C-methyltransferase CobA | strong | 42 | 50 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_0980 | | uroporphyrin-III C-methyltransferase | strong | 39 | 51 |
| | Cellulophaga baltica 18 | M666_RS08190 | | uroporphyrinogen-III C-methyltransferase | insig. | 39 | 52 |
| | Cellulophaga baltica 18 | M666_RS04600 | | uroporphyrinogen-III C-methyltransferase | insig. | 36 | 50 |
| | Caulobacter crescentus NA1000 | CCNA_00654 | | uroporphyrin-III C-methyltransferase | strong | 41 | 51 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_00654 | | uroporphyrin-III C-methyltransferase | cofit | 41 | 51 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS15575 | | uroporphyrin-III C-methyltransferase | cofit | 40 | 56 |
| | Sphingobium sp. HT1-2 | GFF1180 | | Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) | cofit | 41 | 51 |
| | Shewanella amazonensis SB2B | Sama_2187 | | precorrin-2 oxidase / ferrochelatase (RefSeq) | strong | 38 | 58 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS12770 | | uroporphyrinogen-III C-methyltransferase | strong | 38 | 52 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS16245 | | uroporphyrin-III methyltransferase | strong | 41 | 51 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_06860 | | siroheme synthase | insig. | 31 | 65 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c08070 | | uroporphyrin-III C-methyltransferase CobA | no data | 43 | 50 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS12800 | | uroporphyrinogen-III C-methyltransferase | no data | 40 | 51 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS09990 | | uroporphyrinogen-III C-methyltransferase | sig. | 35 | 51 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS04135 | | uroporphyrinogen-III C-methyltransferase | sig. | 33 | 51 |
| | Ralstonia solanacearum GMI1000 | RS_RS12145 | | uroporphyrinogen-III C-methyltransferase | strong | 41 | 50 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS00185 | | uroporphyrinogen-III C-methyltransferase | strong | 41 | 50 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_00966 | | uroporphyrinogen-III C-methyltransferase (EC 2.1.1.107) | insig. | 39 | 52 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_00119 | | uroporphyrinogen-III C-methyltransferase | insig. | 39 | 51 |
| | Paraburkholderia graminis OAS925 | ABIE53_001231 | | uroporphyrin-III C-methyltransferase | strong | 38 | 51 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS04750 | | uroporphyrin-III C-methyltransferase | sig. | 39 | 51 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS04575 | | uroporphyrinogen-III C-methyltransferase | no data | 40 | 52 |
| | Ralstonia solanacearum UW163 | UW163_RS09095 | | uroporphyrinogen-III C-methyltransferase | no data | 40 | 52 |
| | Rhodopseudomonas palustris CGA009 | TX73_010730 | | uroporphyrinogen-III C-methyltransferase | strong | 39 | 50 |
| | Shewanella sp. ANA-3 | Shewana3_1441 | | siroheme synthase (RefSeq) | strong | 33 | 58 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS25230 | | uroporphyrinogen-III C-methyltransferase | sig. | 38 | 51 |
| | Paraburkholderia graminis OAS925 | ABIE53_002204 | | uroporphyrin-III C-methyltransferase | sig. | 37 | 53 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2709.1 | | Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) | insig. | 39 | 47 |
| | Shewanella oneidensis MR-1 | SO3108 | | siroheme synthase, N-terminal component, putative (NCBI ptt file) | strong | 30 | 58 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS09835 | | uroporphyrin-III C-methyltransferase | insig. | 41 | 50 |
| | Shewanella loihica PV-4 | Shew_2332 | | siroheme synthase (RefSeq) | cofit | 32 | 58 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_02714 | | Precorrin-4 C(11)-methyltransferase | cofit | 37 | 50 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_2065 | | Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) | sig. | 35 | 50 |
| | Pseudomonas simiae WCS417 | PS417_12325 | | precorrin-4 C11-methyltransferase | strong | 34 | 50 |
| | Pseudomonas sp. RS175 | PFR28_01372 | | Precorrin-4 C(11)-methyltransferase | sig. | 34 | 50 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3956 | | Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) | cofit | 32 | 51 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS13015 | | precorrin-4 C(11)-methyltransferase | cofit | 34 | 50 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS13015 | | precorrin-4 C(11)-methyltransferase | strong | 34 | 50 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_00530 | | precorrin-4 C11-methyltransferase | strong | 34 | 50 |
| | Pseudomonas sp. SVBP6 | COO64_RS14620 | cobM | precorrin-4 C(11)-methyltransferase | insig. | 34 | 50 |
| | Klebsiella michiganensis M5al | BWI76_RS23060 | | cobalt-precorrin-4 C(11)-methyltransferase | insig. | 32 | 51 |
| | Caulobacter crescentus NA1000 | CCNA_00024 | | uroporphyrin-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase | strong | 30 | 65 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_00024 | | uroporphyrin-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase | cofit | 30 | 65 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_03625 | | cobalt-precorrin-4 methyltransferase | insig. | 31 | 49 |
| | Klebsiella pneumoniae MRSN742743 | GJGHJB_00917 | cbiF | cobalt-precorrin-4 methyltransferase | insig. | 31 | 49 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_0979 | | siroheme synthase, N-terminal domain | no data | 30 | 36 |
| | Pseudomonas protegens RBAN4 | FABNJH_18790 | cobM | precorrin-4 C(11)-methyltransferase | insig. | 35 | 50 |
| | Pseudomonas orientalis W4I3 | QF045_RS14860 | | precorrin-4 C(11)-methyltransferase | insig. | 33 | 50 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_3020 | | precorrin-4 C11-methyltransferase | insig. | 34 | 50 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_3020 | | precorrin-4 C11-methyltransferase | insig. | 34 | 50 |
| | Dechlorosoma suillum PS | Dsui_2959 | | precorrin-4 C11-methyltransferase | insig. | 29 | 51 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_21630 | | precorrin-4 C11-methyltransferase | sig. | 34 | 50 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS02505 | | precorrin-4 C(11)-methyltransferase | no data | 34 | 42 |
| | Methanococcus maripaludis JJ | MMJJ_RS05810 | | precorrin-4 C(11)-methyltransferase | strong | 27 | 50 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_02525 | | siroheme synthase | strong | 30 | 37 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_2850 | | Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) | cofit | 35 | 50 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS02220 | | precorrin-4 C(11)-methyltransferase | insig. | 31 | 50 |
| | Fusobacterium nucleatum SB010 | HUW76_05335 | | precorrin-4 C(11)-methyltransferase | strong | 25 | 50 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS04950 | | TSUP family transporter | strong | 29 | 37 |
| | Pseudomonas aeruginosa MRSN321 | PFGADD_02022 | cobM | precorrin-4 C(11)-methyltransferase | sig. | 32 | 50 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_14995 | | precorrin-4 C(11)-methyltransferase | sig. | 32 | 50 |
| | Pseudomonas aeruginosa PUPa3 | NPBIFN_02061 | cobM | precorrin-4 C(11)-methyltransferase | insig. | 32 | 50 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_1229 | cobM | precorrin-4 C11-methyltransferase | no data | 29 | 47 |
| | Cellulophaga baltica 18 | M666_RS07085 | | bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase | no data | 27 | 40 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_0298 | | siroheme synthase (RefSeq) | no data | 32 | 46 |
| | Pseudomonas sp. DMC3 | GFF3684 | | Precorrin-4 C(11)-methyltransferase | cofit | 33 | 50 |