Conservation of cofitness between PP_1988 and PP_5128 in Pseudomonas putida KT2440

101 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_1988 3-isopropylmalate dehydrogenase 1.0 PP_5128 Dihydroxy-acid dehydratase 0.92 4
Pseudomonas fluorescens FW300-N2E2 0.94 Pf6N2E2_66 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.96 Pf6N2E2_4564 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.95 3
Pseudomonas fluorescens FW300-N2C3 0.94 AO356_21415 3-isopropylmalate dehydrogenase 0.96 AO356_13250 dihydroxy-acid dehydratase 0.96 8
Pseudomonas fluorescens GW456-L13 0.93 PfGW456L13_3945 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.97 PfGW456L13_973 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.89 29
Pseudomonas simiae WCS417 0.93 PS417_18585 3-isopropylmalate dehydrogenase 0.96 PS417_26890 dihydroxy-acid dehydratase 0.91 9
Pseudomonas fluorescens SBW25-INTG 0.93 PFLU_RS20565 3-isopropylmalate dehydrogenase 0.96 PFLU_RS28535 dihydroxy-acid dehydratase 0.86 9
Pseudomonas fluorescens SBW25 0.93 PFLU_RS20565 3-isopropylmalate dehydrogenase 0.96 PFLU_RS28535 dihydroxy-acid dehydratase 0.77 11
Pseudomonas sp. RS175 0.93 PFR28_02821 3-isopropylmalate dehydrogenase 0.96 PFR28_04278 Dihydroxy-acid dehydratase 0.85 4
Pseudomonas fluorescens FW300-N1B4 0.93 Pf1N1B4_12 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.96 Pf1N1B4_2303 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.92 5
Pseudomonas fluorescens FW300-N2E3 0.92 AO353_20635 3-isopropylmalate dehydrogenase 0.97 AO353_08345 dihydroxy-acid dehydratase 0.97 6
Pseudomonas syringae pv. syringae B728a ΔmexB 0.91 Psyr_1985 3-isopropylmalate dehydrogenase 0.94 Psyr_0469 dihydroxyacid dehydratase 0.94 9
Pseudomonas syringae pv. syringae B728a 0.91 Psyr_1985 3-isopropylmalate dehydrogenase 0.94 Psyr_0469 dihydroxyacid dehydratase 0.92 10
Pseudomonas stutzeri RCH2 0.87 Psest_2589 3-isopropylmalate dehydrogenase 0.94 Psest_0234 dihydroxy-acid dehydratase — —
Pseudomonas sp. S08-1 0.87 OH686_04470 3-isopropylmalate dehydrogenase 0.93 OH686_14100 dihydroxy-acid dehydratase 0.92 3
Xanthomonas campestris pv. campestris strain 8004 0.81 Xcc-8004.1053.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.87 Xcc-8004.451.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.79 38
Acinetobacter radioresistens SK82 0.73 MPMX26_00348 3-isopropylmalate dehydrogenase 0.28 MPMX26_03019 Dihydroxy-acid dehydratase 0.93 15
Marinobacter adhaerens HP15 0.73 HP15_1832 3-isopropylmalate dehydrogenase 0.78 HP15_595 dihydroxy-acid dehydratase low > 73
Dechlorosoma suillum PS 0.68 Dsui_3198 3-isopropylmalate dehydrogenase 0.75 Dsui_1122 dihydroxy-acid dehydratase — —
Paraburkholderia bryophila 376MFSha3.1 0.65 H281DRAFT_06072 3-isopropylmalate dehydrogenase 0.80 H281DRAFT_05312 dihydroxyacid dehydratase low > 103
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS14530 3-isopropylmalate dehydrogenase 0.81 ABZR87_RS00240 dihydroxy-acid dehydratase low > 80
Paraburkholderia graminis OAS925 0.65 ABIE53_004804 3-isopropylmalate dehydrogenase 0.80 ABIE53_006513 dihydroxy-acid dehydratase low > 113
Herbaspirillum seropedicae SmR1 0.65 HSERO_RS16500 3-isopropylmalate dehydrogenase 0.72 HSERO_RS02650 dihydroxy-acid dehydratase 0.94 6
Variovorax sp. OAS795 0.64 ABID97_RS08455 3-isopropylmalate dehydrogenase 0.31 ABID97_RS17500 dihydroxy-acid dehydratase — —
Cupriavidus basilensis FW507-4G11 0.64 RR42_RS14385 3-isopropylmalate dehydrogenase 0.30 RR42_RS16210 dihydroxy-acid dehydratase — —
Ralstonia solanacearum GMI1000 0.64 RS_RS09990 3-isopropylmalate dehydrogenase 0.30 RS_RS12105 dihydroxy-acid dehydratase — —
Variovorax sp. SCN45 0.64 GFF3888 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.31 GFF471 Dihydroxy-acid dehydratase (EC 4.2.1.9) — —
Ralstonia solanacearum IBSBF1503 0.64 RALBFv3_RS02610 3-isopropylmalate dehydrogenase 0.29 RALBFv3_RS04535 dihydroxy-acid dehydratase — —
Ralstonia solanacearum UW163 0.64 UW163_RS11115 3-isopropylmalate dehydrogenase 0.29 UW163_RS09135 dihydroxy-acid dehydratase — —
Burkholderia phytofirmans PsJN 0.64 BPHYT_RS33900 3-isopropylmalate dehydrogenase 0.71 BPHYT_RS10100 dihydroxy-acid dehydratase 0.84 39
Acidovorax sp. GW101-3H11 0.64 Ac3H11_1528 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.80 Ac3H11_955 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.72 48
Paraburkholderia sabiae LMG 24235 0.63 QEN71_RS17620 3-isopropylmalate dehydrogenase 0.80 QEN71_RS21095 dihydroxy-acid dehydratase low > 153
Ralstonia solanacearum PSI07 0.63 RPSI07_RS14705 3-isopropylmalate dehydrogenase 0.30 RPSI07_RS12840 dihydroxy-acid dehydratase — —
Castellaniella sp019104865 MT123 0.63 ABCV34_RS04280 3-isopropylmalate dehydrogenase 0.70 ABCV34_RS14810 dihydroxy-acid dehydratase low > 48
Hydrogenophaga sp. GW460-11-11-14-LB1 0.63 GFF3360 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.65 GFF2073 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 90
Desulfovibrio vulgaris Miyazaki F 0.61 DvMF_1794 3-isopropylmalate dehydrogenase (RefSeq) 0.37 DvMF_2034 dihydroxy-acid dehydratase (RefSeq) 0.86 29
Phaeobacter inhibens DSM 17395 0.60 PGA1_c29830 3-isopropylmalate dehydrogenase LeuB 0.73 PGA1_c29490 dihydroxy-acid dehydratase LivD 0.94 5
Rhizobium sp. OAE497 0.58 ABIE40_RS19050 3-isopropylmalate dehydrogenase 0.76 ABIE40_RS08005 dihydroxy-acid dehydratase 0.86 68
Dinoroseobacter shibae DFL-12 0.58 Dshi_0081 3-isopropylmalate dehydrogenase (RefSeq) 0.29 Dshi_0129 dihydroxy-acid dehydratase (RefSeq) — —
Sinorhizobium meliloti 1021 0.58 SMc04405 3-isopropylmalate dehydrogenase 0.77 SMc04045 dihydroxy-acid dehydratase 0.97 8
Synechococcus elongatus PCC 7942 0.58 Synpcc7942_1505 leuB 3-isopropylmalate dehydrogenase 0.74 Synpcc7942_0626 ilvD dihydroxy-acid dehydratase — —
Desulfovibrio vulgaris Hildenborough JW710 0.57 DVU2985 leuB 3-isopropylmalate dehydrogenase (TIGR) 0.37 DVU3373 ilvD dihydroxy-acid dehydratase (TIGR) 0.95 5
Azospirillum sp. SherDot2 0.57 MPMX19_00607 3-isopropylmalate dehydrogenase 0.73 MPMX19_05356 Dihydroxy-acid dehydratase — —
Agrobacterium fabrum C58 0.57 Atu2791 3-isopropylmalate dehydrogenase 0.76 Atu1918 dihydroxy-acid dehydratase — —
Magnetospirillum magneticum AMB-1 0.56 AMB_RS20570 3-isopropylmalate dehydrogenase 0.70 AMB_RS12770 dihydroxy-acid dehydratase — —
Rhodospirillum rubrum S1H 0.56 Rru_A1191 3-isopropylmalate dehydrogenase (NCBI) 0.70 Rru_A1786 Dihydroxy-acid dehydratase (NCBI) 0.89 11
Sphingomonas koreensis DSMZ 15582 0.56 Ga0059261_3190 3-isopropylmalate dehydrogenase 0.28 Ga0059261_4216 Dihydroxyacid dehydratase/phosphogluconate dehydratase 0.97 7
Azospirillum brasilense Sp245 0.55 AZOBR_RS14130 3-isopropylmalate dehydrogenase 0.75 AZOBR_RS15015 dihydroxy-acid dehydratase low > 97
Escherichia coli Nissle 1917 0.54 ECOLIN_RS00395 3-isopropylmalate dehydrogenase 0.74 ECOLIN_RS21665 dihydroxy-acid dehydratase low > 52
Enterobacter sp. TBS_079 0.54 MPMX20_00768 3-isopropylmalate dehydrogenase 0.73 MPMX20_04499 Dihydroxy-acid dehydratase 0.93 16
Escherichia coli ECRC98 0.54 JDDGAC_14315 leuB 3-isopropylmalate dehydrogenase 0.74 JDDGAC_18260 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC99 0.54 KEDOAH_17435 leuB 3-isopropylmalate dehydrogenase 0.74 KEDOAH_13510 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC101 0.54 OKFHMN_10720 leuB 3-isopropylmalate dehydrogenase 0.74 OKFHMN_14640 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC102 0.54 NIAGMN_08570 leuB 3-isopropylmalate dehydrogenase 0.74 NIAGMN_12395 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECOR38 0.54 HEPCGN_08700 leuB 3-isopropylmalate dehydrogenase 0.74 HEPCGN_13350 ilvD dihydroxy-acid dehydratase low > 85
Escherichia coli ECRC101 0.54 MCAODC_01235 leuB 3-isopropylmalate dehydrogenase 0.74 MCAODC_05145 ilvD dihydroxy-acid dehydratase — —
Escherichia fergusonii Becca 0.54 EFB2_03972 3-isopropylmalate dehydrogenase 0.74 EFB2_04865 Dihydroxy-acid dehydratase low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.54 GFF165 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.73 GFF2901 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 78
Escherichia coli BW25113 0.54 b0073 leuB 3-isopropylmalate dehydrogenase (VIMSS) 0.74 b3771 ilvD dihydroxy-acid dehydratase (NCBI) 0.98 5
Enterobacter asburiae PDN3 0.54 EX28DRAFT_3669 3-isopropylmalate dehydrogenase 0.73 EX28DRAFT_4443 dihydroxy-acid dehydratase 0.93 6
Escherichia coli BL21 0.54 ECD_00075 3-isopropylmalate dehydrogenase, NAD(+)-dependent 0.74 ECD_03649 dihydroxyacid dehydratase 0.84 2
Escherichia coli HS(pFamp)R (ATCC 700891) 0.54 OHPLBJKB_03584 3-isopropylmalate dehydrogenase 0.74 OHPLBJKB_04282 Dihydroxy-acid dehydratase low > 73
Escherichia coli ECOR27 0.54 NOLOHH_03065 leuA 2-isopropylmalate synthase 0.74 NOLOHH_06775 ilvD dihydroxy-acid dehydratase low > 57
Escherichia coli ECRC62 0.54 BNILDI_08545 leuA 2-isopropylmalate synthase 0.74 BNILDI_04750 ilvD dihydroxy-acid dehydratase — —
Shewanella loihica PV-4 0.53 Shew_3471 3-isopropylmalate dehydrogenase (RefSeq) 0.74 Shew_0292 dihydroxy-acid dehydratase (RefSeq) 0.99 5
Serratia liquefaciens MT49 0.53 IAI46_03350 3-isopropylmalate dehydrogenase 0.72 IAI46_24345 dihydroxy-acid dehydratase 0.61 37
Klebsiella michiganensis M5al 0.53 BWI76_RS04675 3-isopropylmalate dehydrogenase 0.74 BWI76_RS00975 dihydroxy-acid dehydratase 0.92 11
Bosea sp. OAE506 0.53 ABIE41_RS11860 3-isopropylmalate dehydrogenase 0.30 ABIE41_RS15690 dihydroxy-acid dehydratase — —
Rahnella sp. WP5 0.53 EX31_RS03685 3-isopropylmalate dehydrogenase 0.69 EX31_RS15005 dihydroxy-acid dehydratase 0.99 4
Rhodopseudomonas palustris CGA009 0.53 TX73_001175 3-isopropylmalate dehydrogenase 0.74 TX73_007515 dihydroxy-acid dehydratase — —
Shewanella sp. ANA-3 0.53 Shewana3_3760 3-isopropylmalate dehydrogenase (RefSeq) 0.74 Shewana3_0358 dihydroxy-acid dehydratase (RefSeq) 0.96 6
Shewanella oneidensis MR-1 0.53 SO4235 leuB 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.74 SO4345 ilvD dihydroxy-acid dehydratase (NCBI ptt file) 0.99 4
Vibrio cholerae E7946 ATCC 55056 0.53 CSW01_12600 3-isopropylmalate dehydrogenase 0.77 CSW01_00140 dihydroxy-acid dehydratase low > 62
Shewanella amazonensis SB2B 0.52 Sama_0336 3-isopropylmalate dehydrogenase (RefSeq) 0.74 Sama_3279 dihydroxy-acid dehydratase (RefSeq) 0.97 10
Dickeya dianthicola ME23 0.52 DZA65_RS19205 3-isopropylmalate dehydrogenase 0.72 DZA65_RS21335 dihydroxy-acid dehydratase 0.89 6
Dickeya dianthicola 67-19 0.52 HGI48_RS18060 3-isopropylmalate dehydrogenase 0.73 HGI48_RS20295 dihydroxy-acid dehydratase 0.87 8
Pectobacterium carotovorum WPP14 0.52 HER17_RS03080 3-isopropylmalate dehydrogenase 0.73 HER17_RS01075 dihydroxy-acid dehydratase 0.98 2
Dickeya dadantii 3937 0.52 DDA3937_RS18120 3-isopropylmalate dehydrogenase 0.73 DDA3937_RS20155 dihydroxy-acid dehydratase 0.64 58
Alteromonas macleodii MIT1002 0.51 MIT1002_00948 3-isopropylmalate dehydrogenase 0.78 MIT1002_04041 Dihydroxy-acid dehydratase 0.98 18
Caulobacter crescentus NA1000 0.51 CCNA_00193 3-isopropylmalate dehydrogenase 0.72 CCNA_03139 dihydroxy-acid dehydratase 0.96 10
Caulobacter crescentus NA1000 Δfur 0.51 CCNA_00193 3-isopropylmalate dehydrogenase 0.72 CCNA_03139 dihydroxy-acid dehydratase 0.59 38
Pantoea sp. MT58 0.50 IAI47_16005 3-isopropylmalate dehydrogenase 0.73 IAI47_01035 dihydroxy-acid dehydratase 0.98 3
Erwinia tracheiphila SCR3 0.50 LU632_RS02875 leuB 3-isopropylmalate dehydrogenase 0.72 LU632_RS24400 ilvD dihydroxy-acid dehydratase 0.89 5
Lysobacter sp. OAE881 0.49 ABIE51_RS17585 3-isopropylmalate dehydrogenase 0.27 ABIE51_RS17540 dihydroxy-acid dehydratase 0.97 9
Mucilaginibacter yixingensis YX-36 DSM 26809 0.49 ABZR88_RS11605 3-isopropylmalate dehydrogenase 0.27 ABZR88_RS11575 dihydroxy-acid dehydratase — —
Pedobacter sp. GW460-11-11-14-LB5 0.49 CA265_RS15850 3-isopropylmalate dehydrogenase 0.27 CA265_RS15795 dihydroxy-acid dehydratase 0.95 6
Echinicola vietnamensis KMM 6221, DSM 17526 0.46 Echvi_2062 3-isopropylmalate dehydrogenase 0.28 Echvi_2055 dihydroxy-acid dehydratase — —
Rhodanobacter denitrificans MT42 0.45 LRK55_RS09965 3-isopropylmalate dehydrogenase 0.25 LRK55_RS09960 dihydroxy-acid dehydratase low > 63
Rhodanobacter denitrificans FW104-10B01 0.45 LRK54_RS10325 3-isopropylmalate dehydrogenase 0.25 LRK54_RS10320 dihydroxy-acid dehydratase 0.91 7
Parabacteroides merdae CL09T00C40 0.45 HMPREF1078_RS16640 3-isopropylmalate dehydrogenase 0.63 HMPREF1078_RS16695 dihydroxy-acid dehydratase 0.95 20
Rhodanobacter sp. FW510-T8 0.45 OKGIIK_13595 leuB 3-isopropylmalate dehydrogenase 0.27 OKGIIK_13600 ilvD dihydroxy-acid dehydratase 0.41 51
Bacteroides stercoris CC31F 0.44 HMPREF1181_RS14125 3-isopropylmalate dehydrogenase 0.62 HMPREF1181_RS08335 dihydroxy-acid dehydratase 0.94 4
Brevundimonas sp. GW460-12-10-14-LB2 0.43 A4249_RS09995 3-isopropylmalate dehydrogenase 0.25 A4249_RS10030 dihydroxy-acid dehydratase 0.99 8
Pontibacter actiniarum KMM 6156, DSM 19842 0.43 CA264_09445 3-isopropylmalate dehydrogenase 0.27 CA264_06935 dihydroxy-acid dehydratase low > 74
Bacteroides thetaiotaomicron VPI-5482 0.43 BT1857 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.61 BT2078 dihydroxy-acid dehydratase (NCBI ptt file) 0.88 17
Phocaeicola vulgatus CL09T03C04 0.43 HMPREF1058_RS14565 3-isopropylmalate dehydrogenase 0.62 HMPREF1058_RS16815 dihydroxy-acid dehydratase low > 67
Phocaeicola dorei CL03T12C01 0.43 ABI39_RS10215 3-isopropylmalate dehydrogenase 0.62 ABI39_RS12715 dihydroxy-acid dehydratase 0.92 2
Bacteroides ovatus ATCC 8483 0.42 BACOVA_04600 3-isopropylmalate dehydrogenase 0.60 BACOVA_03302 dihydroxy-acid dehydratase 0.98 3
Dyella japonica UNC79MFTsu3.2 0.42 ABZR86_RS15950 3-isopropylmalate dehydrogenase 0.27 ABZR86_RS15945 dihydroxy-acid dehydratase 0.94 26
Methanococcus maripaludis JJ 0.29 MMJJ_RS02220 3-isopropylmalate dehydrogenase 0.33 MMJJ_RS03675 dihydroxy-acid dehydratase — —
Methanococcus maripaludis S2 0.28 MMP_RS02855 3-isopropylmalate dehydrogenase 0.33 MMP_RS01700 dihydroxy-acid dehydratase — —
Mycobacterium tuberculosis H37Rv 0.27 Rv2995c Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) 0.32 Rv0189c Probable dihydroxy-acid dehydratase IlvD (dad) — —
Bifidobacterium breve UCC2003 0.25 BBR_RS12870 3-isopropylmalate dehydrogenase 0.56 BBR_RS17635 dihydroxy-acid dehydratase low > 34

Not shown: 1 genomes with orthologs for PP_1988 only; 0 genomes with orthologs for PP_5128 only