Conservation of cofitness between CSW01_12465 and CSW01_00015 in Vibrio cholerae E7946 ATCC 55056

119 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_12465 elongation factor 4 1.0 CSW01_00015 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE 0.58 15
Enterobacter sp. TBS_079 0.87 MPMX20_03440 Elongation factor 4 0.75 MPMX20_04650 tRNA modification GTPase MnmE low > 85
Klebsiella michiganensis M5al 0.87 BWI76_RS21335 elongation factor 4 0.77 BWI76_RS00050 tRNA modification GTPase
Erwinia tracheiphila HP pepo 2.2 0.86 IJEDHG_01200 lepA translation elongation factor 4 0.73 IJEDHG_09755 mnmE tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Erwinia tracheiphila SCR3 0.86 LU632_RS15395 lepA translation elongation factor 4 0.73 LU632_RS25300 mnmE tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Serratia liquefaciens MT49 0.86 IAI46_19560 elongation factor 4 0.75 IAI46_25250 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 87
Enterobacter asburiae PDN3 0.86 EX28DRAFT_0076 elongation factor 4 0.75 EX28DRAFT_3993 tRNA modification GTPase TrmE
Dickeya dadantii 3937 0.86 DDA3937_RS15745 elongation factor 4 0.76 DDA3937_RS21310 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 74
Rahnella sp. WP5 0.86 EX31_RS21825 elongation factor 4 0.75 EX31_RS06000 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE 0.64 26
Pantoea agglomerans CFBP13505 P0401 0.86 PagCFBP13505_RS14760 elongation factor 4 0.74 PagCFBP13505_RS19345 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Pectobacterium carotovorum WPP14 0.86 HER17_RS05805 translation elongation factor 4 0.75 HER17_RS21825 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 75
Dickeya dianthicola ME23 0.86 DZA65_RS16910 elongation factor 4 0.75 DZA65_RS22695 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 75
Dickeya dianthicola 67-19 0.86 HGI48_RS15830 elongation factor 4 0.75 HGI48_RS21710 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE 0.67 40
Klebsiella pneumoniae MKP103 0.85 KDGMDA_28455 translation elongation factor 4 0.75 KDGMDA_08700 tRNA modification GTPase MnmE 0.34 35
Escherichia coli ECRC62 0.85 BNILDI_11875 lepA translation elongation factor 4 0.76 BNILDI_04405 tRNA modification GTPase MnmE low > 75
Escherichia coli ECRC100 0.85 OKFHMN_21400 lepA translation elongation factor 4 0.76 OKFHMN_14985 tRNA modification GTPase MnmE
Escherichia coli HS(pFamp)R (ATCC 700891) 0.85 OHPLBJKB_01138 Elongation factor 4 0.76 OHPLBJKB_04346 tRNA modification GTPase MnmE
Escherichia coli ECRC102 0.85 NIAGMN_19170 lepA translation elongation factor 4 0.76 NIAGMN_12740 tRNA modification GTPase MnmE
Escherichia coli ECRC101 0.85 MCAODC_11930 lepA translation elongation factor 4 0.76 MCAODC_05495 tRNA modification GTPase MnmE
Escherichia coli ECOR38 0.85 HEPCGN_20545 lepA translation elongation factor 4 0.76 HEPCGN_13680 tRNA modification GTPase MnmE low > 88
Escherichia coli ECOR27 0.85 NOLOHH_13075 lepA translation elongation factor 4 0.76 NOLOHH_07125 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 76
Escherichia coli Nissle 1917 0.85 ECOLIN_RS14540 translation elongation factor 4 0.76 ECOLIN_RS21345 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 55
Escherichia coli BL21 0.85 ECD_02463 back-translocating elongation factor EF4, GTPase 0.76 ECD_03590 tRNA U34 5-methylaminomethyl-2-thiouridine modification GTPase low > 61
Escherichia coli ECRC98 0.85 JDDGAC_25065 lepA translation elongation factor 4 0.76 JDDGAC_18605 tRNA modification GTPase MnmE
Escherichia coli ECRC99 0.85 KEDOAH_06820 lepA translation elongation factor 4 0.76 KEDOAH_13165 tRNA modification GTPase MnmE
Escherichia coli BW25113 0.85 b2569 lepA GTP-binding protein LepA (NCBI) 0.76 b3706 trmE tRNA modification GTPase (NCBI) 0.29 48
Escherichia fergusonii Becca 0.85 EFB2_01327 Elongation factor 4 0.76 EFB2_04925 tRNA modification GTPase MnmE low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.84 GFF2477 Translation elongation factor LepA 0.76 GFF1750 GTPase and tRNA-U34 5-formylation enzyme TrmE 0.75 12
Pantoea sp. MT58 0.84 IAI47_04870 elongation factor 4 0.73 IAI47_18830 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 76
Erwinia amylovora T8 0.84 OLJFJH_10245 translation elongation factor 4 0.74 OLJFJH_05190 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Shewanella sp. ANA-3 0.83 Shewana3_3028 GTP-binding protein LepA (RefSeq) 0.75 Shewana3_0005 trmE tRNA modification GTPase TrmE (RefSeq) low > 73
Shewanella oneidensis MR-1 0.83 SO1346 lepA GTP-binding protein LepA (NCBI ptt file) 0.75 SO0003 trmE tRNA modification GTPase TrmE (NCBI ptt file) 0.30 18
Shewanella loihica PV-4 0.81 Shew_1052 GTP-binding protein LepA (RefSeq) 0.73 Shew_3865 trmE tRNA modification GTPase TrmE (RefSeq)
Alteromonas macleodii MIT1002 0.81 MIT1002_02715 Elongation factor 4 0.67 MIT1002_04128 tRNA modification GTPase MnmE
Shewanella amazonensis SB2B 0.81 Sama_0878 GTP-binding protein LepA (RefSeq) 0.75 Sama_0008 trmE tRNA modification GTPase TrmE (RefSeq)
Kangiella aquimarina DSM 16071 0.81 B158DRAFT_2184 GTP-binding protein LepA 0.63 B158DRAFT_0373 tRNA modification GTPase TrmE low > 40
Pseudomonas aeruginosa MRSN321 0.78 DY961_RS08665 lepA;go_function=GTPase translation elongation factor 4 0.66 DY961_RS26185 mnmE;go_function=GTPase tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Pseudomonas aeruginosa PUPa3 0.78 DQ20_RS44185 lepA;go_function=GTPase translation elongation factor 4 0.66 DQ20_RS58595 mnmE;go_function=GTPase tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Pseudomonas aeruginosa PA14 0.78 IKLFDK_03290 translation elongation factor 4 0.66 IKLFDK_25575 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 98
Pseudomonas segetis P6 0.76 MPMX49_01405 Elongation factor 4 0.64 MPMX49_00248 tRNA modification GTPase MnmE
Pseudomonas sp. DMC3 0.76 GFF1955 Elongation factor 4 0.64 GFF573 tRNA modification GTPase MnmE
Pseudomonas sp. RS175 0.76 PFR28_03525 Elongation factor 4 0.64 PFR28_04588 tRNA modification GTPase MnmE
Pseudomonas simiae WCS417 0.76 PS417_05180 elongation factor 4 0.64 PS417_28540 tRNA modification GTPase MnmE
Pseudomonas fluorescens GW456-L13 0.76 PfGW456L13_4842 Translation elongation factor LepA 0.64 PfGW456L13_670 GTPase and tRNA-U34 5-formylation enzyme TrmE
Pseudomonas lactucae CFBP13502 0.76 GEMAOFIL_01242 Elongation factor 4 0.64 GEMAOFIL_00178 tRNA modification GTPase MnmE
Pseudomonas fluorescens FW300-N2C3 0.76 AO356_17485 elongation factor 4 0.64 AO356_11660 tRNA modification GTPase MnmE
Pseudomonas fluorescens SBW25-INTG 0.76 PFLU_RS05250 elongation factor 4 0.64 PFLU_RS30195 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Pseudomonas fluorescens SBW25 0.76 PFLU_RS05250 elongation factor 4 0.64 PFLU_RS30195 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 109
Pseudomonas orientalis W4I3 0.76 QF045_RS08170 translation elongation factor 4 0.64 QF045_RS02925 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 93
Pseudomonas stutzeri RCH2 0.76 Psest_3095 GTP-binding protein LepA 0.64 Psest_4373 tRNA modification GTPase TrmE
Pseudomonas fluorescens FW300-N2E3 0.76 AO353_04520 elongation factor 4 0.64 AO353_10455 tRNA modification GTPase MnmE 0.43 34
Pseudomonas fluorescens FW300-N2E2 0.76 Pf6N2E2_5423 Translation elongation factor LepA 0.64 Pf6N2E2_4202 GTPase and tRNA-U34 5-formylation enzyme TrmE
Pseudomonas fluorescens FW300-N1B4 0.76 Pf1N1B4_895 Translation elongation factor LepA 0.64 Pf1N1B4_1933 GTPase and tRNA-U34 5-formylation enzyme TrmE
Pseudomonas sp. S08-1 0.75 OH686_20065 elongation factor 4 0.63 OH686_12655 tRNA modification GTPase TrmE
Pseudomonas putida KT2440 0.75 PP_1431 Elongation factor 4 0.65 PP_0005 GTPase
Pseudomonas sp. SVBP6 0.75 COO64_RS16545 lepA translation elongation factor 4 0.63 COO64_RS02085 mnmE tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Pseudomonas syringae pv. syringae B728a ΔmexB 0.75 Psyr_3954 GTP-binding protein LepA 0.64 Psyr_5133 tRNA modification GTPase trmE 0.34 40
Pseudomonas syringae pv. syringae B728a 0.75 Psyr_3954 GTP-binding protein LepA 0.64 Psyr_5133 tRNA modification GTPase trmE low > 86
Marinobacter adhaerens HP15 0.75 HP15_781 GTP-binding protein LepA 0.68 HP15_3698 tRNA modification GTPase TrmE
Pseudomonas sp. BP01 0.74 JOY50_RS14685 lepA translation elongation factor 4 0.65 JOY50_RS08375 mnmE tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Acinetobacter radioresistens SK82 0.73 MPMX26_02159 Elongation factor 4 0.48 MPMX26_03070 tRNA modification GTPase MnmE low > 36
Burkholderia phytofirmans PsJN 0.73 BPHYT_RS14380 elongation factor 4 0.50 BPHYT_RS19830 tRNA modification GTPase TrmE
Paraburkholderia bryophila 376MFSha3.1 0.72 H281DRAFT_04360 GTP-binding protein LepA 0.49 H281DRAFT_02320 tRNA modification GTPase trmE
Acinetobacter baumannii LAC-4 0.72 RR41_RS04835 translation elongation factor 4 0.50 RR41_RS19010 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Paraburkholderia graminis OAS925 0.72 ABIE53_003038 GTP-binding protein LepA 0.50 ABIE53_000332 tRNA modification GTPase
Herbaspirillum seropedicae SmR1 0.71 HSERO_RS09650 elongation factor 4 0.48 HSERO_RS21670 tRNA modification GTPase TrmE
Paraburkholderia sabiae LMG 24235 0.71 QEN71_RS04600 translation elongation factor 4 0.49 QEN71_RS29655 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Castellaniella sp019104865 MT123 0.70 ABCV34_RS08335 translation elongation factor 4 0.46 ABCV34_RS11895 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Xanthomonas campestris pv. campestris strain 8004 0.70 Xcc-8004.3676.1 Translation elongation factor LepA 0.41 Xcc-8004.5407.1 GTPase and tRNA-U34 5-formylation enzyme TrmE 0.38 8
Cupriavidus basilensis FW507-4G11 0.70 RR42_RS14055 elongation factor 4 0.49 RR42_RS20805 tRNA modification GTPase TrmE
Rhodanobacter sp. FW510-T8 0.70 OKGIIK_07885 Elongation factor 4 0.46 OKGIIK_15285 mnmE tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 53
Rhodanobacter sp000427505 FW510-R12 0.70 LRK53_RS11990 translation elongation factor 4 0.42 LRK53_RS02290 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 59
Rhodanobacter denitrificans MT42 0.70 LRK55_RS16670 translation elongation factor 4 0.46 LRK55_RS08270 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 63
Rhodanobacter denitrificans FW104-10B01 0.70 LRK54_RS16955 translation elongation factor 4 0.46 LRK54_RS08505 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 59
Dyella japonica UNC79MFTsu3.2 0.69 ABZR86_RS07165 translation elongation factor 4 0.46 ABZR86_RS15115 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 74
Lysobacter sp. OAE881 0.69 ABIE51_RS13875 translation elongation factor 4 0.39 ABIE51_RS00735 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE 0.78 28
Dechlorosoma suillum PS 0.69 Dsui_2457 GTP-binding protein LepA 0.45 Dsui_0837 tRNA modification GTPase TrmE low > 51
Ralstonia solanacearum PSI07 0.69 RPSI07_RS18990 elongation factor 4 0.49 RPSI07_RS23950 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Hydrogenophaga sp. GW460-11-11-14-LB1 0.68 GFF3343 Translation elongation factor LepA 0.52 GFF2437 GTPase and tRNA-U34 5-formylation enzyme TrmE
Ralstonia sp. UNC404CL21Col 0.68 ABZR87_RS10190 translation elongation factor 4 0.49 ABZR87_RS05350 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 80
Methylophilus sp. DMC18 0.68 GFF2735 Elongation factor 4 0.49 GFF2105 tRNA modification GTPase MnmE low > 43
Acidovorax sp. GW101-3H11 0.68 Ac3H11_1569 Translation elongation factor LepA 0.51 Ac3H11_4264 GTPase and tRNA-U34 5-formylation enzyme TrmE 0.37 33
Ralstonia solanacearum GMI1000 0.68 RS_RS05250 elongation factor 4 0.49 RS_RS00020 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Ralstonia solanacearum IBSBF1503 0.68 RALBFv3_RS14470 elongation factor 4 0.49 RALBFv3_RS09410 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Ralstonia solanacearum UW163 0.68 UW163_RS11935 elongation factor 4 0.49 UW163_RS04170 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Variovorax sp. SCN45 0.68 GFF3867 Translation elongation factor LepA 0.49 GFF3275 tRNA-5-carboxymethylaminomethyl-2-thiouridine(34) synthesis protein MnmE
Variovorax sp. OAS795 0.67 ABID97_RS08350 translation elongation factor 4 0.50 ABID97_RS02655 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Magnetospirillum magneticum AMB-1 0.64 AMB_RS19545 elongation factor 4 0.27 AMB_RS00005 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Azospirillum brasilense Sp245 0.63 AZOBR_RS00860 elongation factor 4 0.27 AZOBR_RS01805 tRNA modification GTPase TrmE low > 97
Azospirillum sp. SherDot2 0.63 MPMX19_00092 Elongation factor 4 0.26 MPMX19_02568 tRNA modification GTPase MnmE
Xanthobacter sp. DMC5 0.62 GFF2084 Elongation factor 4 0.28 GFF3741 tRNA modification GTPase MnmE
Sinorhizobium meliloti 1021 0.61 SMc00349 GTP-binding protein LepA 0.28 SMc02797 tRNA modification GTPase TrmE
Rhizobium sp. OAE497 0.61 ABIE40_RS01055 translation elongation factor 4 0.28 ABIE40_RS19220 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE 0.27 70
Agrobacterium fabrum C58 0.61 Atu0241 GTP-binding protein LepA 0.28 Atu2832 tRNA modification GTPase
Desulfovibrio vulgaris Miyazaki F 0.61 DvMF_2717 GTP-binding protein LepA (RefSeq) 0.27 DvMF_0886 trmE tRNA modification GTPase TrmE (RefSeq) low > 51
Caulobacter crescentus NA1000 0.61 CCNA_01086 GTP-binding protein lepA 0.28 CCNA_03872 tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase low > 66
Caulobacter crescentus NA1000 Δfur 0.61 CCNA_01086 GTP-binding protein lepA 0.28 CCNA_03872 tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase low > 67
Brevundimonas sp. GW460-12-10-14-LB2 0.61 A4249_RS10390 translation elongation factor 4 0.27 A4249_RS13700 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 48
Sphingobium sp. HT1-2 0.60 GFF3138 Translation elongation factor LepA 0.25 GFF4133 tRNA-5-carboxymethylaminomethyl-2- thiouridine(34) synthesis protein MnmE low > 95
Bosea sp. OAE506 0.60 ABIE41_RS03260 translation elongation factor 4 0.27 ABIE41_RS04680 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 77
Sphingomonas koreensis DSMZ 15582 0.60 Ga0059261_3979 elongation factor 4 0.23 Ga0059261_2204 tRNA modification GTPase trmE low > 68
Dinoroseobacter shibae DFL-12 0.60 Dshi_0809 GTP-binding protein LepA (RefSeq) 0.28 Dshi_3454 tRNA modification GTPase TrmE (RefSeq)
Phaeobacter inhibens DSM 17395 0.60 PGA1_c24090 GTP-binding protein LepA 0.26 PGA1_c35110 tRNA modification GTPase MnmE
Rhodospirillum rubrum S1H 0.60 Rru_A3365 Small GTP-binding protein domain (NCBI) 0.26 Rru_A3624 tRNA modification GTPase TrmE (NCBI)
Desulfovibrio vulgaris Hildenborough JW710 0.60 DVU0703 lepA GTP-binding protein LepA (TIGR) 0.22 DVU1079 trmE tRNA modification GTPase TrmE (TIGR) low > 55
Rhodopseudomonas palustris CGA009 0.59 TX73_001825 translation elongation factor 4 0.30 TX73_001535 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 86
Pontibacter actiniarum KMM 6156, DSM 19842 0.58 CA264_07150 elongation factor 4 0.31 CA264_06625 tRNA modification GTPase
Echinicola vietnamensis KMM 6221, DSM 17526 0.58 Echvi_4645 GTP-binding protein LepA 0.32 Echvi_3509 tRNA modification GTPase TrmE
Synechococcus elongatus PCC 7942 0.57 Synpcc7942_0479 lepA GTP-binding protein LepA 0.26 Synpcc7942_1582 trmE tRNA modification GTPase TrmE
Synechocystis sp000284455 PCC 6803 0.57 SGL_RS18350 translation elongation factor 4 0.26 SGL_RS08695 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Fusobacterium nucleatum SB010 0.57 HUW76_04720 elongation factor 4 0.27 HUW76_10755 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Mucilaginibacter yixingensis YX-36 DSM 26809 0.56 ABZR88_RS09405 translation elongation factor 4 0.29 ABZR88_RS02725 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Cellulophaga baltica 18 0.56 M666_RS04765 translation elongation factor 4 0.30 M666_RS12855 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 67
Parabacteroides merdae CL09T00C40 0.55 HMPREF1078_RS09970 translation elongation factor 4 0.29 HMPREF1078_RS13880 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE 0.75 56
Bacteroides stercoris CC31F 0.55 HMPREF1181_RS16590 elongation factor 4 0.28 HMPREF1181_RS13360 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 56
Pedobacter sp. GW460-11-11-14-LB5 0.55 CA265_RS08955 elongation factor 4 0.28 CA265_RS10450 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
Phocaeicola vulgatus CL09T03C04 0.55 HMPREF1058_RS06410 elongation factor 4 0.28 HMPREF1058_RS05755 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE 0.56 9
Phocaeicola dorei CL03T12C01 0.55 ABI39_RS20175 translation elongation factor 4 0.27 ABI39_RS18355 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 72
Bacteroides ovatus ATCC 8483 0.54 BACOVA_02258 GTP-binding protein LepA 0.28 BACOVA_05338 tRNA modification GTPase TrmE 0.59 11
Bacteroides thetaiotaomicron VPI-5482 0.53 BT0632 GTP-binding protein, membrane GTPase lepA (NCBI ptt file) 0.28 BT4551 putative GTPase, ThdF family (NCBI ptt file)

Not shown: 2 genomes with orthologs for CSW01_12465 only; 0 genomes with orthologs for CSW01_00015 only