Conservation of cofitness between CSW01_02450 and CSW01_00015 in Vibrio cholerae E7946 ATCC 55056

108 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_02450 pyrroline-5-carboxylate reductase 1.0 CSW01_00015 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE 0.85 15
Serratia liquefaciens MT49 0.69 IAI46_21415 pyrroline-5-carboxylate reductase 0.75 IAI46_25250 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 86
Pectobacterium carotovorum WPP14 0.69 HER17_RS03805 pyrroline-5-carboxylate reductase 0.75 HER17_RS21825 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Dickeya dadantii 3937 0.68 DDA3937_RS17305 pyrroline-5-carboxylate reductase 0.76 DDA3937_RS21310 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 74
Dickeya dianthicola 67-19 0.68 HGI48_RS17350 pyrroline-5-carboxylate reductase 0.75 HGI48_RS21710 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Dickeya dianthicola ME23 0.67 DZA65_RS18440 pyrroline-5-carboxylate reductase 0.75 DZA65_RS22695 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Rahnella sp. WP5 0.65 EX31_RS02690 pyrroline-5-carboxylate reductase 0.75 EX31_RS06000 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 89
Alteromonas macleodii MIT1002 0.60 MIT1002_03062 Pyrroline-5-carboxylate reductase 0.67 MIT1002_04128 tRNA modification GTPase MnmE — —
Shewanella oneidensis MR-1 0.57 SO3354 proC pyrroline-5-carboxylate reductase (NCBI ptt file) 0.75 SO0003 trmE tRNA modification GTPase TrmE (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.56 Shewana3_1193 pyrroline-5-carboxylate reductase (RefSeq) 0.75 Shewana3_0005 trmE tRNA modification GTPase TrmE (RefSeq) low > 73
Shewanella loihica PV-4 0.52 Shew_1136 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.73 Shew_3865 trmE tRNA modification GTPase TrmE (RefSeq) — —
Shewanella amazonensis SB2B 0.50 Sama_2478 pyrroline-5-carboxylate reductase (RefSeq) 0.75 Sama_0008 trmE tRNA modification GTPase TrmE (RefSeq) — —
Kangiella aquimarina DSM 16071 0.42 B158DRAFT_0197 pyrroline-5-carboxylate reductase 0.63 B158DRAFT_0373 tRNA modification GTPase TrmE low > 40
Marinobacter adhaerens HP15 0.38 HP15_287 pyrroline-5-carboxylate reductase 0.68 HP15_3698 tRNA modification GTPase TrmE — —
Acinetobacter radioresistens SK82 0.38 MPMX26_00572 Pyrroline-5-carboxylate reductase 0.48 MPMX26_03070 tRNA modification GTPase MnmE low > 36
Pseudomonas sp. BP01 0.37 JOY50_RS20905 proC pyrroline-5-carboxylate reductase 0.65 JOY50_RS08375 mnmE tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Pseudomonas fluorescens SBW25-INTG 0.37 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.64 PFLU_RS30195 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Paraburkholderia graminis OAS925 0.37 ABIE53_000840 pyrroline-5-carboxylate reductase 0.50 ABIE53_000332 tRNA modification GTPase — —
Pseudomonas putida KT2440 0.37 PP_5095 pyrroline-5-carboxylate reductase 0.65 PP_0005 GTPase — —
Lysobacter sp. OAE881 0.37 ABIE51_RS16065 pyrroline-5-carboxylate reductase 0.39 ABIE51_RS00735 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 62
Pseudomonas fluorescens SBW25 0.37 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.64 PFLU_RS30195 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Pseudomonas sp. SVBP6 0.36 COO64_RS12995 proC pyrroline-5-carboxylate reductase 0.63 COO64_RS02085 mnmE tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Pseudomonas simiae WCS417 0.36 PS417_26730 pyrroline-5-carboxylate reductase 0.64 PS417_28540 tRNA modification GTPase MnmE — —
Dechlorosoma suillum PS 0.36 Dsui_0602 pyrroline-5-carboxylate reductase 0.45 Dsui_0837 tRNA modification GTPase TrmE — —
Paraburkholderia sabiae LMG 24235 0.36 QEN71_RS26600 pyrroline-5-carboxylate reductase 0.49 QEN71_RS29655 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.36 Psyr_0476 pyrroline-5-carboxylate reductase 0.64 Psyr_5133 tRNA modification GTPase trmE low > 86
Pseudomonas syringae pv. syringae B728a 0.36 Psyr_0476 pyrroline-5-carboxylate reductase 0.64 Psyr_5133 tRNA modification GTPase trmE — —
Pseudomonas fluorescens FW300-N2C3 0.36 AO356_13420 pyrroline-5-carboxylate reductase 0.64 AO356_11660 tRNA modification GTPase MnmE — —
Pseudomonas fluorescens FW300-N2E3 0.36 AO353_08165 pyrroline-5-carboxylate reductase 0.64 AO353_10455 tRNA modification GTPase MnmE low > 101
Paraburkholderia bryophila 376MFSha3.1 0.35 H281DRAFT_04679 pyrroline-5-carboxylate reductase 0.49 H281DRAFT_02320 tRNA modification GTPase trmE — —
Pseudomonas fluorescens GW456-L13 0.35 PfGW456L13_1010 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.64 PfGW456L13_670 GTPase and tRNA-U34 5-formylation enzyme TrmE — —
Pseudomonas fluorescens FW300-N2E2 0.35 Pf6N2E2_4600 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.64 Pf6N2E2_4202 GTPase and tRNA-U34 5-formylation enzyme TrmE — —
Pseudomonas aeruginosa PA14 0.35 IKLFDK_23455 pyrroline-5-carboxylate reductase 0.66 IKLFDK_25575 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 101
Burkholderia phytofirmans PsJN 0.35 BPHYT_RS03490 pyrroline-5-carboxylate reductase 0.50 BPHYT_RS19830 tRNA modification GTPase TrmE — —
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS01230 pyrroline-5-carboxylate reductase 0.49 ABZR87_RS05350 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Pseudomonas sp. RS175 0.35 PFR28_04243 Pyrroline-5-carboxylate reductase 0.64 PFR28_04588 tRNA modification GTPase MnmE — —
Pseudomonas sp. S08-1 0.35 OH686_10980 pyrroline-5-carboxylate reductase 0.63 OH686_12655 tRNA modification GTPase TrmE — —
Pseudomonas fluorescens FW300-N1B4 0.35 Pf1N1B4_2341 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.64 Pf1N1B4_1933 GTPase and tRNA-U34 5-formylation enzyme TrmE — —
Pseudomonas stutzeri RCH2 0.34 Psest_0283 pyrroline-5-carboxylate reductase 0.64 Psest_4373 tRNA modification GTPase TrmE — —
Pseudomonas sp. DMC3 0.34 GFF210 Pyrroline-5-carboxylate reductase 0.64 GFF573 tRNA modification GTPase MnmE — —
Ralstonia solanacearum GMI1000 0.33 RS_RS13440 pyrroline-5-carboxylate reductase 0.49 RS_RS00020 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Ralstonia solanacearum UW163 0.32 UW163_RS08045 pyrroline-5-carboxylate reductase 0.49 UW163_RS04170 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Ralstonia solanacearum IBSBF1503 0.32 RALBFv3_RS05580 pyrroline-5-carboxylate reductase 0.49 RALBFv3_RS09410 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Dyella japonica UNC79MFTsu3.2 0.32 ABZR86_RS10425 pyrroline-5-carboxylate reductase 0.46 ABZR86_RS15115 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 74
Ralstonia solanacearum PSI07 0.32 RPSI07_RS11720 pyrroline-5-carboxylate reductase 0.49 RPSI07_RS23950 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Variovorax sp. OAS795 0.32 ABID97_RS01555 pyrroline-5-carboxylate reductase 0.50 ABID97_RS02655 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Castellaniella sp019104865 MT123 0.32 ABCV34_RS03610 pyrroline-5-carboxylate reductase 0.46 ABCV34_RS11895 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Acidovorax sp. GW101-3H11 0.32 Ac3H11_788 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.51 Ac3H11_4264 GTPase and tRNA-U34 5-formylation enzyme TrmE — —
Methylophilus sp. DMC18 0.31 GFF863 Pyrroline-5-carboxylate reductase 0.49 GFF2105 tRNA modification GTPase MnmE — —
Variovorax sp. SCN45 0.31 GFF5553 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.49 GFF3275 tRNA-5-carboxymethylaminomethyl-2-thiouridine(34) synthesis protein MnmE — —
Xanthomonas campestris pv. campestris strain 8004 0.30 Xcc-8004.1710.1 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.41 Xcc-8004.5407.1 GTPase and tRNA-U34 5-formylation enzyme TrmE low > 74
Rhodanobacter sp000427505 FW510-R12 0.30 LRK53_RS05680 pyrroline-5-carboxylate reductase 0.42 LRK53_RS02290 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 60
Cupriavidus basilensis FW507-4G11 0.30 RR42_RS17360 pyrroline-5-carboxylate reductase 0.49 RR42_RS20805 tRNA modification GTPase TrmE — —
Rhodanobacter sp. FW510-T8 0.30 OKGIIK_11135 proC pyrroline-5-carboxylate reductase 0.46 OKGIIK_15285 mnmE tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 52
Rhodanobacter denitrificans MT42 0.29 LRK55_RS04030 pyrroline-5-carboxylate reductase 0.46 LRK55_RS08270 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Rhodanobacter denitrificans FW104-10B01 0.29 LRK54_RS04260 pyrroline-5-carboxylate reductase 0.46 LRK54_RS08505 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 59
Herbaspirillum seropedicae SmR1 0.29 HSERO_RS18990 pyrroline-5-carboxylate reductase 0.48 HSERO_RS21670 tRNA modification GTPase TrmE — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.28 GFF2806 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.52 GFF2437 GTPase and tRNA-U34 5-formylation enzyme TrmE — —
Magnetospirillum magneticum AMB-1 0.28 AMB_RS02820 pyrroline-5-carboxylate reductase 0.27 AMB_RS00005 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Escherichia fergusonii Becca 0.27 EFB2_03670 Pyrroline-5-carboxylate reductase 0.76 EFB2_04925 tRNA modification GTPase MnmE low > 86
Enterobacter asburiae PDN3 0.27 EX28DRAFT_2585 pyrroline-5-carboxylate reductase 0.75 EX28DRAFT_3993 tRNA modification GTPase TrmE — —
Enterobacter sp. TBS_079 0.27 MPMX20_00976 Pyrroline-5-carboxylate reductase 0.75 MPMX20_04650 tRNA modification GTPase MnmE low > 85
Klebsiella michiganensis M5al 0.27 BWI76_RS06170 pyrroline-5-carboxylate reductase 0.77 BWI76_RS00050 tRNA modification GTPase — —
Escherichia coli BL21 0.27 ECD_00333 pyrroline-5-carboxylate reductase, NAD(P)-binding 0.76 ECD_03590 tRNA U34 5-methylaminomethyl-2-thiouridine modification GTPase low > 61
Escherichia coli ECOR38 0.27 HEPCGN_07250 proC pyrroline-5-carboxylate reductase 0.76 HEPCGN_13680 tRNA modification GTPase MnmE low > 87
Escherichia coli BW25113 0.27 b0386 proC pyrroline-5-carboxylate reductase (NCBI) 0.76 b3706 trmE tRNA modification GTPase (NCBI) low > 76
Escherichia coli Nissle 1917 0.27 ECOLIN_RS02345 pyrroline-5-carboxylate reductase 0.76 ECOLIN_RS21345 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 55
Escherichia coli HS(pFamp)R (ATCC 700891) 0.27 OHPLBJKB_03288 Pyrroline-5-carboxylate reductase 0.76 OHPLBJKB_04346 tRNA modification GTPase MnmE — —
Escherichia coli ECOR27 0.27 NOLOHH_01535 proC pyrroline-5-carboxylate reductase 0.76 NOLOHH_07125 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 75
Escherichia coli ECRC62 0.27 BNILDI_22950 proC pyrroline-5-carboxylate reductase 0.76 BNILDI_04405 tRNA modification GTPase MnmE low > 75
Escherichia coli ECRC101 0.27 MCAODC_27835 proC pyrroline-5-carboxylate reductase 0.76 MCAODC_05495 tRNA modification GTPase MnmE — —
Escherichia coli ECRC99 0.27 KEDOAH_19355 proC pyrroline-5-carboxylate reductase 0.76 KEDOAH_13165 tRNA modification GTPase MnmE — —
Escherichia coli ECRC98 0.27 JDDGAC_12265 proC pyrroline-5-carboxylate reductase 0.76 JDDGAC_18605 tRNA modification GTPase MnmE — —
Escherichia coli ECRC100 0.27 OKFHMN_08610 proC pyrroline-5-carboxylate reductase 0.76 OKFHMN_14985 tRNA modification GTPase MnmE — —
Escherichia coli ECRC102 0.27 NIAGMN_06665 proC pyrroline-5-carboxylate reductase 0.76 NIAGMN_12740 tRNA modification GTPase MnmE — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.26 GFF4283 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.76 GFF1750 GTPase and tRNA-U34 5-formylation enzyme TrmE low > 78
Erwinia amylovora T8 0.26 OLJFJH_18285 pyrroline-5-carboxylate reductase 0.74 OLJFJH_05190 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Pantoea sp. MT58 0.26 IAI47_14945 pyrroline-5-carboxylate reductase 0.73 IAI47_18830 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 76
Synechocystis sp000284455 PCC 6803 0.25 SGL_RS17305 pyrroline-5-carboxylate reductase 0.26 SGL_RS08695 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Azospirillum sp. SherDot2 0.25 MPMX19_01399 Pyrroline-5-carboxylate reductase 0.26 MPMX19_02568 tRNA modification GTPase MnmE — —
Desulfovibrio vulgaris Hildenborough JW710 0.24 DVU2332 proC pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.22 DVU1079 trmE tRNA modification GTPase TrmE (TIGR) low > 55
Agrobacterium fabrum C58 0.24 Atu2209 pyrroline-5-carboxylate reductase 0.28 Atu2832 tRNA modification GTPase low > 89
Sinorhizobium meliloti 1021 0.24 SMc02677 pyrroline-5-carboxylate reductase 0.28 SMc02797 tRNA modification GTPase TrmE — —
Rhodopseudomonas palustris CGA009 0.24 TX73_022630 pyrroline-5-carboxylate reductase 0.30 TX73_001535 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Erwinia tracheiphila SCR3 0.23 LU632_RS18995 proC pyrroline-5-carboxylate reductase 0.73 LU632_RS25300 mnmE tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Rhodospirillum rubrum S1H 0.23 Rru_A3281 Delta 1-pyrroline-5-carboxylate reductase (NCBI) 0.26 Rru_A3624 tRNA modification GTPase TrmE (NCBI) — —
Azospirillum brasilense Sp245 0.23 AZOBR_RS06245 pyrroline-5-carboxylate reductase 0.27 AZOBR_RS01805 tRNA modification GTPase TrmE — —
Rhizobium sp. OAE497 0.23 ABIE40_RS13005 pyrroline-5-carboxylate reductase 0.28 ABIE40_RS19220 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 107
Echinicola vietnamensis KMM 6221, DSM 17526 0.23 Echvi_2635 pyrroline-5-carboxylate reductase 0.32 Echvi_3509 tRNA modification GTPase TrmE — —
Xanthobacter sp. DMC5 0.22 GFF1925 Pyrroline-5-carboxylate reductase 0.28 GFF3741 tRNA modification GTPase MnmE — —
Sphingomonas koreensis DSMZ 15582 0.22 Ga0059261_3321 pyrroline-5-carboxylate reductase 0.23 Ga0059261_2204 tRNA modification GTPase trmE low > 68
Desulfovibrio vulgaris Miyazaki F 0.21 DvMF_3161 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.27 DvMF_0886 trmE tRNA modification GTPase TrmE (RefSeq) low > 51
Synechococcus elongatus PCC 7942 0.21 Synpcc7942_2058 proC pyrroline-5-carboxylate reductase 0.26 Synpcc7942_1582 trmE tRNA modification GTPase TrmE — —
Bacteroides ovatus ATCC 8483 0.21 BACOVA_03587 pyrroline-5-carboxylate reductase 0.28 BACOVA_05338 tRNA modification GTPase TrmE low > 94
Dinoroseobacter shibae DFL-12 0.20 Dshi_2645 pyrroline-5-carboxylate reductase (RefSeq) 0.28 Dshi_3454 tRNA modification GTPase TrmE (RefSeq) — —
Caulobacter crescentus NA1000 0.20 CCNA_00528 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.28 CCNA_03872 tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase low > 66
Caulobacter crescentus NA1000 Δfur 0.20 CCNA_00528 pyrroline-5-carboxylate reductase 0.28 CCNA_03872 tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase low > 67
Bacteroides thetaiotaomicron VPI-5482 0.19 BT3757 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.28 BT4551 putative GTPase, ThdF family (NCBI ptt file) low > 81
Bosea sp. OAE506 0.19 ABIE41_RS11365 pyrroline-5-carboxylate reductase 0.27 ABIE41_RS04680 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Phaeobacter inhibens DSM 17395 0.19 PGA1_c24700 pyrroline-5-carboxylate reductase ProC 0.26 PGA1_c35110 tRNA modification GTPase MnmE — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.18 ABZR88_RS09865 pyrroline-5-carboxylate reductase 0.29 ABZR88_RS02725 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.16 CA264_07730 pyrroline-5-carboxylate reductase 0.31 CA264_06625 tRNA modification GTPase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.16 A4249_RS09840 pyrroline-5-carboxylate reductase dimerization domain-containing protein 0.27 A4249_RS13700 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 48
Pedobacter sp. GW460-11-11-14-LB5 0.15 CA265_RS18505 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.28 CA265_RS10450 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE — —
Phocaeicola vulgatus CL09T03C04 0.15 HMPREF1058_RS08830 pyrroline-5-carboxylate reductase 0.28 HMPREF1058_RS05755 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 67
Phocaeicola dorei CL03T12C01 0.15 ABI39_RS02960 pyrroline-5-carboxylate reductase 0.27 ABI39_RS18355 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 72
Parabacteroides merdae CL09T00C40 0.15 HMPREF1078_RS10620 pyrroline-5-carboxylate reductase 0.29 HMPREF1078_RS13880 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 61
Bacteroides stercoris CC31F 0.15 HMPREF1181_RS03440 pyrroline-5-carboxylate reductase 0.28 HMPREF1181_RS13360 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 56
Cellulophaga baltica 18 0.14 M666_RS02635 pyrroline-5-carboxylate reductase 0.30 M666_RS12855 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE low > 67

Not shown: 2 genomes with orthologs for CSW01_02450 only; 1 genomes with orthologs for CSW01_00015 only