Conservation of cofitness between b2021 and b3771 in Escherichia coli BW25113

100 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2021 hisC histidinol-phosphate aminotransferase (NCBI) 1.0 b3771 ilvD dihydroxy-acid dehydratase (NCBI) 0.97 5
Escherichia coli ECRC101 1.00 OKFHMN_24510 hisC histidinol-phosphate transaminase 1.00 OKFHMN_14640 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC98 1.00 JDDGAC_28620 hisC histidinol-phosphate transaminase 1.00 JDDGAC_18260 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC101 1.00 MCAODC_20430 hisC histidinol-phosphate transaminase 1.00 MCAODC_05145 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC99 1.00 KEDOAH_03640 hisC histidinol-phosphate transaminase 1.00 KEDOAH_13510 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECOR27 1.00 NOLOHH_15825 hisC histidinol-phosphate transaminase 1.00 NOLOHH_06775 ilvD dihydroxy-acid dehydratase low > 57
Escherichia fergusonii Becca 1.00 EFB2_01835 Histidinol-phosphate aminotransferase 0.99 EFB2_04865 Dihydroxy-acid dehydratase low > 86
Escherichia coli ECRC102 1.00 NIAGMN_22455 hisC histidinol-phosphate transaminase 1.00 NIAGMN_12395 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC62 0.99 BNILDI_14735 hisC histidinol-phosphate transaminase 1.00 BNILDI_04750 ilvD dihydroxy-acid dehydratase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_01679 Histidinol-phosphate aminotransferase 1.00 OHPLBJKB_04282 Dihydroxy-acid dehydratase low > 73
Escherichia coli ECOR38 0.99 HEPCGN_03215 hisC histidinol-phosphate transaminase 1.00 HEPCGN_13350 ilvD dihydroxy-acid dehydratase low > 85
Escherichia coli BL21 0.99 ECD_01923 histidinol-phosphate aminotransferase 1.00 ECD_03649 dihydroxyacid dehydratase low > 60
Escherichia coli Nissle 1917 0.99 ECOLIN_RS11950 histidinol-phosphate transaminase 0.99 ECOLIN_RS21665 dihydroxy-acid dehydratase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.91 GFF3911 Histidinol-phosphate aminotransferase (EC 2.6.1.9) 0.97 GFF2901 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 78
Enterobacter sp. TBS_079 0.89 MPMX20_03003 Histidinol-phosphate aminotransferase 0.97 MPMX20_04499 Dihydroxy-acid dehydratase 0.96 6
Enterobacter asburiae PDN3 0.89 EX28DRAFT_0538 histidinol-phosphate aminotransferase 0.96 EX28DRAFT_4443 dihydroxy-acid dehydratase 0.88 21
Klebsiella michiganensis M5al 0.87 BWI76_RS18930 histidinol-phosphate transaminase 0.96 BWI76_RS00975 dihydroxy-acid dehydratase 0.88 8
Serratia liquefaciens MT49 0.78 IAI46_08205 histidinol-phosphate transaminase 0.90 IAI46_24345 dihydroxy-acid dehydratase low > 86
Rahnella sp. WP5 0.76 EX31_RS11445 histidinol-phosphate transaminase 0.87 EX31_RS15005 dihydroxy-acid dehydratase 0.97 12
Erwinia tracheiphila SCR3 0.76 LU632_RS08940 hisC histidinol-phosphate transaminase 0.86 LU632_RS24400 ilvD dihydroxy-acid dehydratase low > 74
Pantoea sp. MT58 0.76 IAI47_07085 histidinol-phosphate transaminase 0.89 IAI47_01035 dihydroxy-acid dehydratase 0.98 8
Pectobacterium carotovorum WPP14 0.74 HER17_RS12235 histidinol-phosphate transaminase 0.91 HER17_RS01075 dihydroxy-acid dehydratase 0.99 1
Dickeya dianthicola ME23 0.73 DZA65_RS10050 histidinol-phosphate transaminase 0.91 DZA65_RS21335 dihydroxy-acid dehydratase 0.70 24
Dickeya dianthicola 67-19 0.73 HGI48_RS09740 histidinol-phosphate transaminase 0.91 HGI48_RS20295 dihydroxy-acid dehydratase 0.88 6
Dickeya dadantii 3937 0.73 DDA3937_RS09730 histidinol-phosphate transaminase 0.92 DDA3937_RS20155 dihydroxy-acid dehydratase 0.91 21
Vibrio cholerae E7946 ATCC 55056 0.58 CSW01_05755 histidinol-phosphate transaminase 0.85 CSW01_00140 dihydroxy-acid dehydratase low > 62
Alteromonas macleodii MIT1002 0.49 MIT1002_02634 Histidinol-phosphate aminotransferase 0.79 MIT1002_04041 Dihydroxy-acid dehydratase 0.97 21
Shewanella sp. ANA-3 0.42 Shewana3_1852 histidinol phosphate aminotransferase (RefSeq) 0.80 Shewana3_0358 dihydroxy-acid dehydratase (RefSeq) 0.97 2
Shewanella oneidensis MR-1 0.42 SO2072 hisC histidinol-phosphate aminotransferase (NCBI ptt file) 0.80 SO4345 ilvD dihydroxy-acid dehydratase (NCBI ptt file) 0.99 4
Shewanella loihica PV-4 0.40 Shew_2199 histidinol-phosphate aminotransferase (RefSeq) 0.78 Shew_0292 dihydroxy-acid dehydratase (RefSeq) 0.96 16
Xanthomonas campestris pv. campestris strain 8004 0.38 Xcc-8004.2947.1 Histidinol-phosphate aminotransferase (EC 2.6.1.9) 0.72 Xcc-8004.451.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.65 57
Rhodanobacter sp. FW510-T8 0.38 OKGIIK_04955 hisC histidinol-phosphate transaminase 0.27 OKGIIK_13600 ilvD dihydroxy-acid dehydratase low > 52
Rhodanobacter denitrificans FW104-10B01 0.38 LRK54_RS01600 histidinol-phosphate transaminase 0.26 LRK54_RS10320 dihydroxy-acid dehydratase 0.59 32
Rhodanobacter denitrificans MT42 0.37 LRK55_RS01380 histidinol-phosphate transaminase 0.26 LRK55_RS09960 dihydroxy-acid dehydratase low > 63
Pedobacter sp. GW460-11-11-14-LB5 0.36 CA265_RS03630 histidinol-phosphate transaminase 0.27 CA265_RS15795 dihydroxy-acid dehydratase 0.92 22
Pontibacter actiniarum KMM 6156, DSM 19842 0.35 CA264_05035 histidinol-phosphate transaminase 0.28 CA264_06935 dihydroxy-acid dehydratase low > 74
Dyella japonica UNC79MFTsu3.2 0.35 ABZR86_RS06725 histidinol-phosphate transaminase 0.28 ABZR86_RS15945 dihydroxy-acid dehydratase 0.93 52
Mucilaginibacter yixingensis YX-36 DSM 26809 0.34 ABZR88_RS06875 histidinol-phosphate transaminase 0.27 ABZR88_RS11575 dihydroxy-acid dehydratase 0.82 1
Lysobacter sp. OAE881 0.34 ABIE51_RS13320 histidinol-phosphate transaminase 0.27 ABIE51_RS17540 dihydroxy-acid dehydratase 0.96 17
Shewanella amazonensis SB2B 0.33 Sama_1943 histidinol-phosphate aminotransferase (RefSeq) 0.79 Sama_3279 dihydroxy-acid dehydratase (RefSeq) 0.97 7
Parabacteroides merdae CL09T00C40 0.32 HMPREF1078_RS02445 histidinol-phosphate transaminase 0.65 HMPREF1078_RS16695 dihydroxy-acid dehydratase low > 61
Echinicola vietnamensis KMM 6221, DSM 17526 0.32 Echvi_2458 histidinol-phosphate aminotransferase 0.29 Echvi_2055 dihydroxy-acid dehydratase 0.91 11
Bacteroides stercoris CC31F 0.29 HMPREF1181_RS04855 histidinol-phosphate transaminase 0.64 HMPREF1181_RS08335 dihydroxy-acid dehydratase 0.85 40
Bacteroides ovatus ATCC 8483 0.29 BACOVA_01233 histidinol-phosphate transaminase 0.62 BACOVA_03302 dihydroxy-acid dehydratase 0.94 25
Phocaeicola vulgatus CL09T03C04 0.28 HMPREF1058_RS15880 histidinol-phosphate transaminase 0.64 HMPREF1058_RS16815 dihydroxy-acid dehydratase 0.87 26
Phocaeicola dorei CL03T12C01 0.28 ABI39_RS11840 histidinol-phosphate transaminase 0.64 ABI39_RS12715 dihydroxy-acid dehydratase 0.77 17
Bacteroides thetaiotaomicron VPI-5482 0.27 BT0202 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) 0.63 BT2078 dihydroxy-acid dehydratase (NCBI ptt file) 0.93 11
Paraburkholderia sabiae LMG 24235 0.20 QEN71_RS27860 histidinol-phosphate transaminase 0.74 QEN71_RS21095 dihydroxy-acid dehydratase low > 153
Ralstonia sp. UNC404CL21Col 0.19 ABZR87_RS02495 histidinol-phosphate transaminase 0.75 ABZR87_RS00240 dihydroxy-acid dehydratase low > 80
Paraburkholderia graminis OAS925 0.19 ABIE53_003700 histidinol-phosphate aminotransferase 0.74 ABIE53_006513 dihydroxy-acid dehydratase low > 113
Hydrogenophaga sp. GW460-11-11-14-LB1 0.19 GFF1493 Histidinol-phosphate aminotransferase (EC 2.6.1.9) 0.64 GFF2073 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 90
Ralstonia solanacearum GMI1000 0.19 RS_RS14785 histidinol-phosphate aminotransferase 1 0.28 RS_RS12105 dihydroxy-acid dehydratase — —
Paraburkholderia bryophila 376MFSha3.1 0.19 H281DRAFT_05654 histidinol phosphate aminotransferase apoenzyme 0.74 H281DRAFT_05312 dihydroxyacid dehydratase low > 103
Ralstonia solanacearum PSI07 0.19 RPSI07_RS10395 histidinol-phosphate transaminase 0.29 RPSI07_RS12840 dihydroxy-acid dehydratase — —
Methanococcus maripaludis S2 0.19 MMP_RS06260 histidinol-phosphate transaminase 0.35 MMP_RS01700 dihydroxy-acid dehydratase — —
Magnetospirillum magneticum AMB-1 0.19 AMB_RS00655 histidinol-phosphate aminotransferase family protein 0.73 AMB_RS12770 dihydroxy-acid dehydratase — —
Desulfovibrio vulgaris Hildenborough JW710 0.19 DVU1029 hisC histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) 0.39 DVU3373 ilvD dihydroxy-acid dehydratase (TIGR) 0.79 27
Methanococcus maripaludis JJ 0.19 MMJJ_RS08090 histidinol-phosphate transaminase 0.35 MMJJ_RS03675 dihydroxy-acid dehydratase — —
Mycobacterium tuberculosis H37Rv 0.18 Rv1600 Probable histidinol-phosphate aminotransferase HisC1 0.31 Rv0189c Probable dihydroxy-acid dehydratase IlvD (dad) — —
Ralstonia solanacearum UW163 0.18 UW163_RS06775 histidinol-phosphate transaminase 0.29 UW163_RS09135 dihydroxy-acid dehydratase — —
Ralstonia solanacearum IBSBF1503 0.18 RALBFv3_RS06840 histidinol-phosphate transaminase 0.29 RALBFv3_RS04535 dihydroxy-acid dehydratase — —
Pseudomonas stutzeri RCH2 0.18 Psest_1985 histidinol-phosphate aminotransferase 0.75 Psest_0234 dihydroxy-acid dehydratase — —
Variovorax sp. SCN45 0.18 GFF5348 Histidinol-phosphate aminotransferase (EC 2.6.1.9) 0.31 GFF471 Dihydroxy-acid dehydratase (EC 4.2.1.9) — —
Acidovorax sp. GW101-3H11 0.18 Ac3H11_4729 histidinol-phosphate transaminase (EC 2.6.1.9) (from data) 0.74 Ac3H11_955 Dihydroxy-acid dehydratase (EC 4.2.1.9) — —
Pseudomonas fluorescens FW300-N2C3 0.18 AO356_03460 aspartate aminotransferase 0.75 AO356_13250 dihydroxy-acid dehydratase low > 104
Marinobacter adhaerens HP15 0.18 HP15_2427 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) 0.70 HP15_595 dihydroxy-acid dehydratase low > 73
Pseudomonas fluorescens FW300-N2E3 0.18 AO353_02065 aspartate aminotransferase 0.75 AO353_08345 dihydroxy-acid dehydratase 0.55 4
Cupriavidus basilensis FW507-4G11 0.18 RR42_RS18910 histidinol-phosphate aminotransferase 0.29 RR42_RS16210 dihydroxy-acid dehydratase — —
Pseudomonas fluorescens FW300-N2E2 0.18 Pf6N2E2_2519 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) 0.75 Pf6N2E2_4564 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 103
Desulfovibrio vulgaris Miyazaki F 0.18 DvMF_0908 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) 0.39 DvMF_2034 dihydroxy-acid dehydratase (RefSeq) 0.86 28
Burkholderia phytofirmans PsJN 0.18 BPHYT_RS02830 aspartate aminotransferase 0.74 BPHYT_RS10100 dihydroxy-acid dehydratase low > 109
Pseudomonas fluorescens FW300-N1B4 0.18 Pf1N1B4_349 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) 0.75 Pf1N1B4_2303 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.54 15
Castellaniella sp019104865 MT123 0.18 ABCV34_RS02645 histidinol-phosphate transaminase 0.72 ABCV34_RS14810 dihydroxy-acid dehydratase low > 48
Pseudomonas sp. RS175 0.17 PFR28_00908 Histidinol-phosphate aminotransferase 0.75 PFR28_04278 Dihydroxy-acid dehydratase low > 88
Acinetobacter radioresistens SK82 0.17 MPMX26_02586 Histidinol-phosphate aminotransferase 0.29 MPMX26_03019 Dihydroxy-acid dehydratase 0.84 30
Pseudomonas simiae WCS417 0.17 PS417_08130 aspartate aminotransferase 0.75 PS417_26890 dihydroxy-acid dehydratase 0.22 22
Pseudomonas sp. S08-1 0.17 OH686_20875 histidinol-phosphate transaminase 0.75 OH686_14100 dihydroxy-acid dehydratase low > 80
Variovorax sp. OAS795 0.17 ABID97_RS23145 histidinol-phosphate transaminase 0.31 ABID97_RS17500 dihydroxy-acid dehydratase — —
Pseudomonas fluorescens GW456-L13 0.17 PfGW456L13_2177 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) 0.75 PfGW456L13_973 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.46 15
Pseudomonas fluorescens SBW25 0.17 PFLU_RS08100 histidinol-phosphate transaminase 0.75 PFLU_RS28535 dihydroxy-acid dehydratase low > 109
Pseudomonas fluorescens SBW25-INTG 0.17 PFLU_RS08100 histidinol-phosphate transaminase 0.75 PFLU_RS28535 dihydroxy-acid dehydratase low > 109
Pseudomonas putida KT2440 0.17 PP_0967 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) 0.74 PP_5128 Dihydroxy-acid dehydratase 0.93 6
Azospirillum brasilense Sp245 0.16 AZOBR_RS20485 histidinol-phosphate aminotransferase [EC:2.6.1.9] (from data) 0.74 AZOBR_RS15015 dihydroxy-acid dehydratase low > 97
Herbaspirillum seropedicae SmR1 0.16 HSERO_RS23520 histidinol-phosphate aminotransferase 0.74 HSERO_RS02650 dihydroxy-acid dehydratase low > 78
Rhodospirillum rubrum S1H 0.16 Rru_A3264 Histidinol-phosphate aminotransferase (NCBI) 0.71 Rru_A1786 Dihydroxy-acid dehydratase (NCBI) 0.84 12
Azospirillum sp. SherDot2 0.16 MPMX19_04389 Histidinol-phosphate aminotransferase 0.74 MPMX19_05356 Dihydroxy-acid dehydratase — —
Synechococcus elongatus PCC 7942 0.16 Synpcc7942_1030 hisC histidinol-phosphate aminotransferase 0.75 Synpcc7942_0626 ilvD dihydroxy-acid dehydratase — —
Caulobacter crescentus NA1000 Δfur 0.16 CCNA_02617 histidinol-phosphate aminotransferase 0.72 CCNA_03139 dihydroxy-acid dehydratase low > 67
Caulobacter crescentus NA1000 0.16 CCNA_02617 histidinol-phosphate aminotransferase 0.72 CCNA_03139 dihydroxy-acid dehydratase low > 66
Pseudomonas syringae pv. syringae B728a ΔmexB 0.15 Psyr_4132 histidinol phosphate aminotransferase apoenzyme 0.74 Psyr_0469 dihydroxyacid dehydratase 0.89 4
Dechlorosoma suillum PS 0.15 Dsui_1414 histidinol-phosphate aminotransferase 0.74 Dsui_1122 dihydroxy-acid dehydratase — —
Pseudomonas syringae pv. syringae B728a 0.15 Psyr_4132 histidinol phosphate aminotransferase apoenzyme 0.74 Psyr_0469 dihydroxyacid dehydratase 0.94 7
Brevundimonas sp. GW460-12-10-14-LB2 0.15 A4249_RS11450 histidinol-phosphate transaminase 0.25 A4249_RS10030 dihydroxy-acid dehydratase 0.98 27
Phaeobacter inhibens DSM 17395 0.15 PGA1_c25240 histidinol-phosphate aminotransferase [EC:2.6.1.9] (from data) 0.70 PGA1_c29490 dihydroxy-acid dehydratase LivD — —
Bifidobacterium breve UCC2003 0.14 BBR_RS17050 histidinol-phosphate transaminase 0.56 BBR_RS17635 dihydroxy-acid dehydratase 0.25 18
Sphingomonas koreensis DSMZ 15582 0.14 Ga0059261_2299 histidinol-phosphate aminotransferase 0.28 Ga0059261_4216 Dihydroxyacid dehydratase/phosphogluconate dehydratase 0.99 10
Dinoroseobacter shibae DFL-12 0.14 Dshi_2946 histidinol-phosphate aminotransferase (RefSeq) 0.31 Dshi_0129 dihydroxy-acid dehydratase (RefSeq) — —
Sinorhizobium meliloti 1021 0.13 SMc00710 histidinol-phosphate aminotransferase 0.75 SMc04045 dihydroxy-acid dehydratase low > 103
Rhizobium sp. OAE497 0.12 ABIE40_RS17595 histidinol-phosphate transaminase 0.75 ABIE40_RS08005 dihydroxy-acid dehydratase 0.91 42
Rhodopseudomonas palustris CGA009 0.12 TX73_023035 histidinol-phosphate transaminase 0.74 TX73_007515 dihydroxy-acid dehydratase — —
Agrobacterium fabrum C58 0.11 Atu2810 cobalamin biosynthetic protein 0.73 Atu1918 dihydroxy-acid dehydratase — —

Not shown: 1 genomes with orthologs for b2021 only; 1 genomes with orthologs for b3771 only