Conservation of cofitness between b2499 and b4005 in Escherichia coli BW25113

102 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2499 purM phosphoribosylaminoimidazole synthetase (NCBI) 1.0 b4005 purD phosphoribosylamine--glycine ligase (NCBI) 0.97 2
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01227 Phosphoribosylformylglycinamidine cyclo-ligase 0.99 OHPLBJKB_04044 Phosphoribosylamine--glycine ligase 0.37 25
Escherichia coli BL21 1.00 ECD_02391 phosphoribosylaminoimidazole synthetase 0.98 ECD_03882 phosphoribosylglycinamide synthetase phosphoribosylamine-glycine ligase 0.85 3
Escherichia coli Nissle 1917 1.00 ECOLIN_RS14190 phosphoribosylformylglycinamidine cyclo-ligase 0.98 ECOLIN_RS23095 phosphoribosylamine--glycine ligase low > 52
Escherichia coli ECRC62 0.99 BNILDI_12270 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.99 BNILDI_06060 purD Phosphoribosylamine--glycine ligase — —
Escherichia coli ECOR27 0.99 NOLOHH_13460 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.99 NOLOHH_05460 purD Phosphoribosylamine--glycine ligase low > 57
Escherichia coli ECOR38 0.99 HEPCGN_20975 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.98 HEPCGN_11955 purD Phosphoribosylamine--glycine ligase low > 85
Escherichia fergusonii Becca 0.99 EFB2_01399 Phosphoribosylformylglycinamidine cyclo-ligase 0.98 EFB2_04605 Phosphoribosylamine--glycine ligase low > 86
Escherichia coli ECRC98 0.99 JDDGAC_25755 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.98 JDDGAC_16940 purD Phosphoribosylamine--glycine ligase — —
Escherichia coli ECRC99 0.99 KEDOAH_06410 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.98 KEDOAH_14845 purD Phosphoribosylamine--glycine ligase — —
Escherichia coli ECRC101 0.99 MCAODC_12340 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.98 MCAODC_03815 purD Phosphoribosylamine--glycine ligase — —
Escherichia coli ECRC102 0.99 NIAGMN_19580 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.98 NIAGMN_11065 purD Phosphoribosylamine--glycine ligase — —
Escherichia coli ECRC101 0.99 OKFHMN_21810 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.98 OKFHMN_13315 purD Phosphoribosylamine--glycine ligase — —
Enterobacter asburiae PDN3 0.94 EX28DRAFT_0168 phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.92 EX28DRAFT_4544 phosphoribosylamine--glycine ligase (EC 6.3.4.13) — —
Enterobacter sp. TBS_079 0.94 MPMX20_03354 Phosphoribosylformylglycinamidine cyclo-ligase 0.92 MPMX20_00225 Phosphoribosylamine--glycine ligase 0.97 2
Klebsiella michiganensis M5al 0.93 BWI76_RS20965 phosphoribosylformylglycinamidine cyclo-ligase 0.92 BWI76_RS01610 phosphoribosylamine--glycine ligase 0.88 4
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF2169 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.93 GFF4187 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.53 11
Rahnella sp. WP5 0.90 EX31_RS22695 phosphoribosylformylglycinamidine cyclo-ligase 0.82 EX31_RS16855 phosphoribosylamine--glycine ligase 0.97 3
Pantoea sp. MT58 0.89 IAI47_05180 phosphoribosylformylglycinamidine cyclo-ligase 0.84 IAI47_18045 phosphoribosylamine--glycine ligase 0.98 4
Pectobacterium carotovorum WPP14 0.88 HER17_RS15465 phosphoribosylformylglycinamidine cyclo-ligase 0.82 HER17_RS20340 phosphoribosylamine--glycine ligase 0.96 4
Serratia liquefaciens MT49 0.88 IAI46_18885 phosphoribosylformylglycinamidine cyclo-ligase 0.81 IAI46_01360 phosphoribosylamine--glycine ligase 0.58 6
Erwinia tracheiphila SCR3 0.87 LU632_RS08275 purM phosphoribosylformylglycinamidine cyclo-ligase 0.81 LU632_RS01015 purD phosphoribosylamine--glycine ligase 0.95 4
Dickeya dadantii 3937 0.87 DDA3937_RS06025 phosphoribosylformylglycinamidine cyclo-ligase 0.83 DDA3937_RS01215 phosphoribosylamine--glycine ligase 0.92 5
Dickeya dianthicola ME23 0.86 DZA65_RS06420 phosphoribosylformylglycinamidine cyclo-ligase 0.83 DZA65_RS01255 phosphoribosylamine--glycine ligase 0.95 2
Dickeya dianthicola 67-19 0.86 HGI48_RS06070 phosphoribosylformylglycinamidine cyclo-ligase 0.83 HGI48_RS01210 phosphoribosylamine--glycine ligase 0.87 3
Shewanella amazonensis SB2B 0.77 Sama_2097 phosphoribosylaminoimidazole synthetase (RefSeq) 0.71 Sama_0394 phosphoribosylamine--glycine ligase (RefSeq) 0.98 1
Vibrio cholerae E7946 ATCC 55056 0.77 CSW01_11350 phosphoribosylformylglycinamidine cyclo-ligase 0.79 CSW01_01415 phosphoribosylamine--glycine ligase low > 62
Shewanella sp. ANA-3 0.76 Shewana3_2545 phosphoribosylaminoimidazole synthetase (RefSeq) 0.70 Shewana3_0440 phosphoribosylamine--glycine ligase (RefSeq) 0.95 2
Shewanella oneidensis MR-1 0.75 SO2760 purM phosphoribosylformylglycinamidine cyclo-ligase (NCBI ptt file) 0.68 SO0441 purD phosphoribosylamine--glycine ligase (NCBI ptt file) 0.97 1
Shewanella loihica PV-4 0.75 Shew_1513 phosphoribosylaminoimidazole synthetase (RefSeq) 0.67 Shew_3413 phosphoribosylamine--glycine ligase (RefSeq) — —
Alteromonas macleodii MIT1002 0.73 MIT1002_02219 Phosphoribosylformylglycinamidine cyclo-ligase 0.72 MIT1002_03961 Phosphoribosylamine--glycine ligase 0.99 5
Kangiella aquimarina DSM 16071 0.70 B158DRAFT_2385 phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.71 B158DRAFT_0167 phosphoribosylamine--glycine ligase (EC 6.3.4.13) — —
Pseudomonas stutzeri RCH2 0.70 Psest_1474 phosphoribosylaminoimidazole synthetase 0.73 Psest_1013 phosphoribosylamine--glycine ligase 0.91 3
Pseudomonas putida KT2440 0.69 PP_1665 Phosphoribosylformylglycinamidine cyclo-ligase 0.74 PP_4823 Phosphoribosylamine--glycine ligase — —
Pseudomonas fluorescens SBW25 0.69 PFLU_RS22065 phosphoribosylformylglycinamidine cyclo-ligase 0.73 PFLU_RS03010 phosphoribosylamine--glycine ligase — —
Pseudomonas fluorescens SBW25-INTG 0.69 PFLU_RS22065 phosphoribosylformylglycinamidine cyclo-ligase 0.73 PFLU_RS03010 phosphoribosylamine--glycine ligase — —
Pseudomonas sp. S08-1 0.69 OH686_18995 Phosphoribosylformylglycinamidine cyclo-ligase 0.72 OH686_07625 Phosphoribosylamine--glycine ligase — —
Pseudomonas syringae pv. syringae B728a 0.69 Psyr_3689 phosphoribosylformylglycinamidine cyclo-ligase 0.73 Psyr_4407 phosphoribosylamine--glycine ligase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.69 Psyr_3689 phosphoribosylformylglycinamidine cyclo-ligase 0.73 Psyr_4407 phosphoribosylamine--glycine ligase — —
Pseudomonas simiae WCS417 0.69 PS417_20120 phosphoribosylaminoimidazole synthetase 0.72 PS417_02935 phosphoribosylamine--glycine ligase — —
Pseudomonas fluorescens FW300-N2E2 0.69 Pf6N2E2_5729 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.73 Pf6N2E2_3520 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) — —
Pseudomonas fluorescens FW300-N2C3 0.69 AO356_19090 phosphoribosylaminoimidazole synthetase 0.73 AO356_08230 phosphoribosylamine--glycine ligase — —
Pseudomonas fluorescens FW300-N1B4 0.68 Pf1N1B4_3698 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.73 Pf1N1B4_1316 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) — —
Pseudomonas sp. RS175 0.68 PFR28_03217 Phosphoribosylformylglycinamidine cyclo-ligase 0.73 PFR28_05213 Phosphoribosylamine--glycine ligase — —
Pseudomonas fluorescens FW300-N2E3 0.68 AO353_02680 phosphoribosylaminoimidazole synthetase 0.73 AO353_13645 phosphoribosylamine--glycine ligase — —
Pseudomonas fluorescens GW456-L13 0.68 PfGW456L13_4252 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.72 PfGW456L13_58 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) — —
Marinobacter adhaerens HP15 0.67 HP15_1299 phosphoribosylaminoimidazole synthetase 0.75 HP15_3228 phosphoribosylamine-glycine ligase — —
Acinetobacter radioresistens SK82 0.67 MPMX26_02206 Phosphoribosylformylglycinamidine cyclo-ligase 0.64 MPMX26_01140 Phosphoribosylamine--glycine ligase 0.98 2
Dechlorosoma suillum PS 0.62 Dsui_1519 phosphoribosylaminoimidazole synthetase 0.62 Dsui_1596 phosphoribosylamine--glycine ligase — —
Cupriavidus basilensis FW507-4G11 0.59 RR42_RS17220 phosphoribosylaminoimidazole synthetase 0.56 RR42_RS04730 phosphoribosylamine--glycine ligase — —
Castellaniella sp019104865 MT123 0.56 ABCV34_RS08795 phosphoribosylformylglycinamidine cyclo-ligase 0.57 ABCV34_RS02550 phosphoribosylamine--glycine ligase — —
Herbaspirillum seropedicae SmR1 0.56 HSERO_RS03165 phosphoribosylaminoimidazole synthetase 0.60 HSERO_RS17755 phosphoribosylamine--glycine ligase — —
Rhodanobacter denitrificans FW104-10B01 0.56 LRK54_RS12945 phosphoribosylformylglycinamidine cyclo-ligase 0.63 LRK54_RS10165 phosphoribosylamine--glycine ligase low > 59
Rhodospirillum rubrum S1H 0.56 Rru_A2167 Phosphoribosylformylglycinamidine cyclo-ligase (NCBI) 0.48 Rru_A0646 Phosphoribosylamine--glycine ligase (NCBI) — —
Rhodanobacter denitrificans MT42 0.56 LRK55_RS12645 phosphoribosylformylglycinamidine cyclo-ligase 0.63 LRK55_RS09805 phosphoribosylamine--glycine ligase low > 63
Paraburkholderia sabiae LMG 24235 0.55 QEN71_RS26445 phosphoribosylformylglycinamidine cyclo-ligase 0.58 QEN71_RS24400 phosphoribosylamine--glycine ligase 0.95 3
Variovorax sp. OAS795 0.55 ABID97_RS08700 phosphoribosylformylglycinamidine cyclo-ligase 0.56 ABID97_RS16735 phosphoribosylamine--glycine ligase — —
Variovorax sp. SCN45 0.55 GFF3941 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.56 GFF302 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.91 9
Ralstonia solanacearum PSI07 0.55 RPSI07_RS12020 phosphoribosylformylglycinamidine cyclo-ligase 0.58 RPSI07_RS13680 phosphoribosylamine--glycine ligase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.55 GFF3433 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.57 GFF4524 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) — —
Acidovorax sp. GW101-3H11 0.55 Ac3H11_1318 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.58 Ac3H11_2421 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) — —
Ralstonia solanacearum IBSBF1503 0.55 RALBFv3_RS05280 phosphoribosylformylglycinamidine cyclo-ligase 0.57 RALBFv3_RS03545 phosphoribosylamine--glycine ligase — —
Ralstonia solanacearum UW163 0.55 UW163_RS08345 phosphoribosylformylglycinamidine cyclo-ligase 0.57 UW163_RS10125 phosphoribosylamine--glycine ligase — —
Ralstonia sp. UNC404CL21Col 0.55 ABZR87_RS00915 phosphoribosylformylglycinamidine cyclo-ligase 0.58 ABZR87_RS15410 phosphoribosylamine--glycine ligase — —
Burkholderia phytofirmans PsJN 0.54 BPHYT_RS03640 phosphoribosylformylglycinamidine cyclo-ligase 0.59 BPHYT_RS06405 phosphoribosylamine--glycine ligase 0.82 6
Ralstonia solanacearum GMI1000 0.54 RS_RS13145 phosphoribosylformylglycinamidine cyclo-ligase 0.58 RS_RS10995 phosphoribosylamine--glycine ligase — —
Azospirillum brasilense Sp245 0.54 AZOBR_RS16290 phosphoribosylaminoimidazole synthetase 0.53 AZOBR_RS04470 phosphoribosylamine--glycine ligase — —
Xanthomonas campestris pv. campestris strain 8004 0.54 Xcc-8004.1676.1 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.66 Xcc-8004.657.1 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) 0.92 3
Lysobacter sp. OAE881 0.54 ABIE51_RS15890 phosphoribosylformylglycinamidine cyclo-ligase 0.63 ABIE51_RS17770 phosphoribosylamine--glycine ligase 0.93 3
Paraburkholderia bryophila 376MFSha3.1 0.54 H281DRAFT_04710 phosphoribosylformylglycinamidine cyclo-ligase 0.59 H281DRAFT_04521 phosphoribosylamine--glycine ligase — —
Paraburkholderia graminis OAS925 0.54 ABIE53_000874 phosphoribosylformylglycinamidine cyclo-ligase 0.59 ABIE53_001545 phosphoribosylamine--glycine ligase — —
Agrobacterium fabrum C58 0.53 Atu1141 Phosphoribosylglycinamide synthetase 0.54 Atu0647 phosphoribosylamine--glycine ligase 0.96 2
Azospirillum sp. SherDot2 0.53 MPMX19_01304 Phosphoribosylformylglycinamidine cyclo-ligase 0.53 MPMX19_01630 Phosphoribosylamine--glycine ligase 0.89 7
Synechococcus elongatus PCC 7942 0.53 Synpcc7942_0851 purM phosphoribosylaminoimidazole synthetase 0.42 Synpcc7942_0925 purD phosphoribosylamine--glycine ligase — —
Dyella japonica UNC79MFTsu3.2 0.53 ABZR86_RS19865 phosphoribosylformylglycinamidine cyclo-ligase 0.64 ABZR86_RS13850 phosphoribosylamine--glycine ligase 0.58 9
Rhizobium sp. OAE497 0.52 ABIE40_RS06560 phosphoribosylformylglycinamidine cyclo-ligase 0.54 ABIE40_RS05430 phosphoribosylamine--glycine ligase 0.90 20
Phaeobacter inhibens DSM 17395 0.52 PGA1_c13260 phosphoribosylformylglycinamidine cyclo-ligase PurM 0.47 PGA1_c23610 phosphoribosylamine--glycine ligase PurD 0.92 3
Rhodanobacter sp. FW510-T8 0.52 OKGIIK_02315 purM phosphoribosylformylglycinamidine cyclo-ligase 0.62 OKGIIK_13750 purD phosphoribosylamine--glycine ligase 0.73 42
Magnetospirillum magneticum AMB-1 0.52 AMB_RS14330 phosphoribosylformylglycinamidine cyclo-ligase 0.53 AMB_RS01075 phosphoribosylamine--glycine ligase — —
Sphingomonas koreensis DSMZ 15582 0.51 Ga0059261_0228 phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.44 Ga0059261_1441 phosphoribosylamine--glycine ligase (EC 6.3.4.13) — —
Sinorhizobium meliloti 1021 0.51 SMc00615 phosphoribosylaminoimidazole synthetase 0.52 SMc00993 phosphoribosylamine--glycine ligase 0.98 2
Caulobacter crescentus NA1000 Δfur 0.50 CCNA_01775 phosphoribosylformylglycinamidine cyclo-ligase 0.43 CCNA_00299 phosphoribosylamine--glycine ligase low > 67
Caulobacter crescentus NA1000 0.50 CCNA_01775 phosphoribosylformylglycinamidine cyclo-ligase 0.43 CCNA_00299 phosphoribosylamine--glycine ligase 0.96 1
Desulfovibrio vulgaris Miyazaki F 0.49 DvMF_0202 phosphoribosylaminoimidazole synthetase (RefSeq) 0.49 DvMF_1722 phosphoribosylamine--glycine ligase (RefSeq) — —
Dinoroseobacter shibae DFL-12 0.49 Dshi_1889 phosphoribosylformylglycinamidine cyclo-ligase (RefSeq) 0.45 Dshi_2728 phosphoribosylamine--glycine ligase (RefSeq) 0.94 2
Desulfovibrio vulgaris Hildenborough JW710 0.48 DVU1406 purM phosphoribosylformylglycinamidine cyclo-ligase (TIGR) 0.48 DVU0488 purD phosphoribosylamine--glycine ligase (TIGR) — —
Brevundimonas sp. GW460-12-10-14-LB2 0.48 A4249_RS08210 phosphoribosylformylglycinamidine cyclo-ligase 0.43 A4249_RS09255 phosphoribosylamine--glycine ligase — —
Bosea sp. OAE506 0.48 ABIE41_RS17040 phosphoribosylformylglycinamidine cyclo-ligase 0.49 ABIE41_RS23160 phosphoribosylamine--glycine ligase 0.88 4
Bifidobacterium breve UCC2003 0.47 BBR_RS13375 phosphoribosylformylglycinamidine cyclo-ligase 0.42 BBR_RS13370 phosphoribosylamine--glycine ligase 0.84 5
Rhodopseudomonas palustris CGA009 0.47 TX73_015785 phosphoribosylformylglycinamidine cyclo-ligase 0.53 TX73_005965 phosphoribosylamine--glycine ligase — —
Fusobacterium nucleatum SB010 0.47 HUW76_05175 phosphoribosylformylglycinamidine cyclo-ligase 0.43 HUW76_05205 phosphoribosylamine--glycine ligase 0.99 4
Mycobacterium tuberculosis H37Rv 0.40 Rv0809 Probable phosphoribosylformylglycinamidine CYCLO-ligase PurM (AIRS) (phosphoribosyl-aminoimidazole synthetase) (air synthase) 0.34 Rv0772 Probable phosphoribosylamine--glycine ligase PurD (GARS) (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase) (5'-phosphoribosylglycinamide synthetase) — —
Methanococcus maripaludis S2 0.29 MMP_RS06450 phosphoribosylformylglycinamidine cyclo-ligase 0.23 MMP_RS02095 phosphoribosylamine--glycine ligase — —
Methanococcus maripaludis JJ 0.29 MMJJ_RS07900 phosphoribosylformylglycinamidine cyclo-ligase 0.23 MMJJ_RS03210 phosphoribosylamine--glycine ligase — —
Bacteroides stercoris CC31F 0.10 HMPREF1181_RS06340 phosphoribosylformylglycinamidine cyclo-ligase 0.44 HMPREF1181_RS01580 phosphoribosylamine--glycine ligase 0.90 7
Parabacteroides merdae CL09T00C40 0.10 HMPREF1078_RS13965 AIR synthase-related protein 0.44 HMPREF1078_RS06805 phosphoribosylamine--glycine ligase 0.75 5
Phocaeicola dorei CL03T12C01 0.10 ABI39_RS00475 phosphoribosylformylglycinamidine cyclo-ligase 0.43 ABI39_RS06055 phosphoribosylamine--glycine ligase 0.87 2
Bacteroides thetaiotaomicron VPI-5482 0.10 BT4211 putative phosphoribosylformylglycinamidine cyclo-ligase (NCBI ptt file) 0.43 BT3253 phosphoribosylamine--glycine ligase (NCBI ptt file) 0.91 2
Bacteroides ovatus ATCC 8483 0.10 BACOVA_05058 hypothetical protein 0.42 BACOVA_01348 phosphoribosylamine--glycine ligase 0.95 3
Phocaeicola vulgatus CL09T03C04 0.10 HMPREF1058_RS08025 phosphoribosylformylglycinamidine cyclo-ligase 0.43 HMPREF1058_RS10995 phosphoribosylamine--glycine ligase 0.87 2
Pedobacter sp. GW460-11-11-14-LB5 0.09 CA265_RS05175 phosphoribosylformylglycinamidine cyclo-ligase 0.39 CA265_RS22605 phosphoribosylamine--glycine ligase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.08 Echvi_0734 Phosphoribosylaminoimidazole (AIR) synthetase 0.44 Echvi_0167 phosphoribosylamine--glycine ligase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.08 CA264_17695 phosphoribosylformylglycinamidine cyclo-ligase 0.42 CA264_20115 phosphoribosylamine--glycine ligase 0.40 46

Not shown: 0 genomes with orthologs for b2499 only; 1 genomes with orthologs for b4005 only