Conservation of cofitness between PP_1988 and PP_1025 in Pseudomonas putida KT2440

95 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_1988 3-isopropylmalate dehydrogenase 1.0 PP_1025 2-isopropylmalate synthase 0.90 13
Pseudomonas fluorescens FW300-N2E2 0.94 Pf6N2E2_66 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.91 Pf6N2E2_3170 2-isopropylmalate synthase (EC 2.3.3.13) 0.95 4
Pseudomonas fluorescens FW300-N2C3 0.94 AO356_21415 3-isopropylmalate dehydrogenase 0.91 AO356_06550 2-isopropylmalate synthase 0.97 1
Pseudomonas fluorescens GW456-L13 0.93 PfGW456L13_3945 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.91 PfGW456L13_4854 2-isopropylmalate synthase (EC 2.3.3.13) 0.97 6
Pseudomonas simiae WCS417 0.93 PS417_18585 3-isopropylmalate dehydrogenase 0.91 PS417_23110 2-isopropylmalate synthase 0.96 1
Pseudomonas fluorescens SBW25 0.93 PFLU_RS20565 3-isopropylmalate dehydrogenase 0.91 PFLU_RS24765 2-isopropylmalate synthase 0.94 1
Pseudomonas fluorescens SBW25-INTG 0.93 PFLU_RS20565 3-isopropylmalate dehydrogenase 0.91 PFLU_RS24765 2-isopropylmalate synthase 0.94 2
Pseudomonas sp. RS175 0.93 PFR28_02821 3-isopropylmalate dehydrogenase 0.91 PFR28_00305 2-isopropylmalate synthase 0.89 2
Pseudomonas fluorescens FW300-N1B4 0.93 Pf1N1B4_12 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.91 Pf1N1B4_847 2-isopropylmalate synthase (EC 2.3.3.13) 0.96 1
Pseudomonas fluorescens FW300-N2E3 0.92 AO353_20635 3-isopropylmalate dehydrogenase 0.91 AO353_15925 2-isopropylmalate synthase 0.97 7
Pseudomonas syringae pv. syringae B728a 0.91 Psyr_1985 3-isopropylmalate dehydrogenase 0.91 Psyr_1257 2-isopropylmalate synthase 0.94 6
Pseudomonas syringae pv. syringae B728a ΔmexB 0.91 Psyr_1985 3-isopropylmalate dehydrogenase 0.91 Psyr_1257 2-isopropylmalate synthase 0.96 5
Pseudomonas stutzeri RCH2 0.87 Psest_2589 3-isopropylmalate dehydrogenase 0.83 Psest_1277 2-isopropylmalate synthase, yeast type 0.69 34
Pseudomonas sp. S08-1 0.87 OH686_04470 3-isopropylmalate dehydrogenase 0.78 OH686_17570 2-isopropylmalate synthase 0.76 28
Xanthomonas campestris pv. campestris strain 8004 0.81 Xcc-8004.1053.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.10 Xcc-8004.1056.1 2-isopropylmalate synthase (EC 2.3.3.13) 0.88 17
Acinetobacter radioresistens SK82 0.73 MPMX26_00348 3-isopropylmalate dehydrogenase 0.62 MPMX26_00404 2-isopropylmalate synthase 0.90 21
Marinobacter adhaerens HP15 0.73 HP15_1832 3-isopropylmalate dehydrogenase 0.53 HP15_2055 2-isopropylmalate synthase 0.66 42
Dechlorosoma suillum PS 0.68 Dsui_3198 3-isopropylmalate dehydrogenase 0.59 Dsui_3227 2-isopropylmalate synthase — —
Paraburkholderia bryophila 376MFSha3.1 0.65 H281DRAFT_06072 3-isopropylmalate dehydrogenase 0.63 H281DRAFT_00385 2-isopropylmalate synthase low > 103
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS14530 3-isopropylmalate dehydrogenase 0.63 ABZR87_RS22365 2-isopropylmalate synthase low > 80
Paraburkholderia graminis OAS925 0.65 ABIE53_004804 3-isopropylmalate dehydrogenase 0.63 ABIE53_002867 2-isopropylmalate synthase low > 113
Herbaspirillum seropedicae SmR1 0.65 HSERO_RS16500 3-isopropylmalate dehydrogenase 0.66 HSERO_RS17185 2-isopropylmalate synthase 0.95 3
Variovorax sp. OAS795 0.64 ABID97_RS08455 3-isopropylmalate dehydrogenase 0.60 ABID97_RS14905 2-isopropylmalate synthase — —
Cupriavidus basilensis FW507-4G11 0.64 RR42_RS14385 3-isopropylmalate dehydrogenase 0.62 RR42_RS21205 2-isopropylmalate synthase low > 128
Ralstonia solanacearum GMI1000 0.64 RS_RS09990 3-isopropylmalate dehydrogenase 0.63 RS_RS18695 2-isopropylmalate synthase 2 low > 80
Variovorax sp. SCN45 0.64 GFF3888 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.60 GFF1164 2-isopropylmalate synthase (EC 2.3.3.13) low > 127
Ralstonia solanacearum UW163 0.64 UW163_RS11115 3-isopropylmalate dehydrogenase 0.65 UW163_RS17345 2-isopropylmalate synthase — —
Ralstonia solanacearum IBSBF1503 0.64 RALBFv3_RS02610 3-isopropylmalate dehydrogenase 0.65 RALBFv3_RS21840 2-isopropylmalate synthase low > 76
Burkholderia phytofirmans PsJN 0.64 BPHYT_RS33900 3-isopropylmalate dehydrogenase 0.64 BPHYT_RS13280 2-isopropylmalate synthase low > 109
Acidovorax sp. GW101-3H11 0.64 Ac3H11_1528 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.55 Ac3H11_5000 2-isopropylmalate synthase (EC 2.3.3.13) low > 79
Ralstonia solanacearum PSI07 0.63 RPSI07_RS14705 3-isopropylmalate dehydrogenase 0.64 RPSI07_RS01320 2-isopropylmalate synthase low > 81
Paraburkholderia sabiae LMG 24235 0.63 QEN71_RS17620 3-isopropylmalate dehydrogenase 0.57 QEN71_RS01640 2-isopropylmalate synthase low > 153
Castellaniella sp019104865 MT123 0.63 ABCV34_RS04280 3-isopropylmalate dehydrogenase 0.61 ABCV34_RS12420 2-isopropylmalate synthase 0.56 9
Hydrogenophaga sp. GW460-11-11-14-LB1 0.63 GFF3360 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.62 GFF4280 2-isopropylmalate synthase (EC 2.3.3.13) 0.69 24
Desulfovibrio vulgaris Miyazaki F 0.61 DvMF_1794 3-isopropylmalate dehydrogenase (RefSeq) 0.13 DvMF_1791 2-isopropylmalate synthase (RefSeq) 0.94 8
Phaeobacter inhibens DSM 17395 0.60 PGA1_c29830 3-isopropylmalate dehydrogenase LeuB 0.10 PGA1_c26470 2-isopropylmalate synthase LeuA 0.95 2
Dinoroseobacter shibae DFL-12 0.58 Dshi_0081 3-isopropylmalate dehydrogenase (RefSeq) 0.10 Dshi_0596 2-isopropylmalate synthase (RefSeq) — —
Rhizobium sp. OAE497 0.58 ABIE40_RS19050 3-isopropylmalate dehydrogenase 0.52 ABIE40_RS13330 2-isopropylmalate synthase 0.99 2
Sinorhizobium meliloti 1021 0.58 SMc04405 3-isopropylmalate dehydrogenase 0.54 SMc02717 2-isopropylmalate synthase 0.99 1
Synechococcus elongatus PCC 7942 0.58 Synpcc7942_1505 leuB 3-isopropylmalate dehydrogenase 0.09 Synpcc7942_1410 leuA 2-isopropylmalate synthase — —
Azospirillum sp. SherDot2 0.57 MPMX19_00607 3-isopropylmalate dehydrogenase 0.57 MPMX19_01822 2-isopropylmalate synthase 0.90 9
Desulfovibrio vulgaris Hildenborough JW710 0.57 DVU2985 leuB 3-isopropylmalate dehydrogenase (TIGR) 0.12 DVU2981 leuA 2-isopropylmalate synthase (TIGR) 0.98 3
Agrobacterium fabrum C58 0.57 Atu2791 3-isopropylmalate dehydrogenase 0.55 Atu2264 2-isopropylmalate synthase 0.99 2
Magnetospirillum magneticum AMB-1 0.56 AMB_RS20570 3-isopropylmalate dehydrogenase 0.57 AMB_RS17550 2-isopropylmalate synthase — —
Rhodospirillum rubrum S1H 0.56 Rru_A1191 3-isopropylmalate dehydrogenase (NCBI) 0.57 Rru_A1928 Yeast 2-isopropylmalate synthase (NCBI) 0.90 9
Sphingomonas koreensis DSMZ 15582 0.56 Ga0059261_3190 3-isopropylmalate dehydrogenase 0.59 Ga0059261_4031 2-isopropylmalate synthase, yeast type 0.97 5
Azospirillum brasilense Sp245 0.55 AZOBR_RS14130 3-isopropylmalate dehydrogenase 0.57 AZOBR_RS12155 2-isopropylmalate synthase 0.87 5
Escherichia coli Nissle 1917 0.54 ECOLIN_RS00395 3-isopropylmalate dehydrogenase 0.09 ECOLIN_RS00400 2-isopropylmalate synthase low > 52
Enterobacter sp. TBS_079 0.54 MPMX20_00768 3-isopropylmalate dehydrogenase 0.56 MPMX20_03565 2-isopropylmalate synthase low > 85
Escherichia coli ECRC101 0.54 MCAODC_01235 leuB 3-isopropylmalate dehydrogenase 0.09 MCAODC_01230 2-isopropylmalate synthase — —
Escherichia coli ECRC102 0.54 NIAGMN_08570 leuB 3-isopropylmalate dehydrogenase 0.09 NIAGMN_08565 2-isopropylmalate synthase — —
Escherichia fergusonii Becca 0.54 EFB2_03972 3-isopropylmalate dehydrogenase 0.09 EFB2_03971 2-isopropylmalate synthase low > 86
Escherichia coli ECRC98 0.54 JDDGAC_14315 leuB 3-isopropylmalate dehydrogenase 0.09 JDDGAC_14310 2-isopropylmalate synthase — —
Escherichia coli ECRC101 0.54 OKFHMN_10720 leuB 3-isopropylmalate dehydrogenase 0.09 OKFHMN_10715 2-isopropylmalate synthase — —
Escherichia coli ECOR38 0.54 HEPCGN_08700 leuB 3-isopropylmalate dehydrogenase 0.09 HEPCGN_08695 2-isopropylmalate synthase low > 85
Escherichia coli ECRC99 0.54 KEDOAH_17435 leuB 3-isopropylmalate dehydrogenase 0.09 KEDOAH_17440 2-isopropylmalate synthase — —
Escherichia coli BW25113 0.54 b0073 leuB 3-isopropylmalate dehydrogenase (VIMSS) 0.09 b0074 leuA 2-isopropylmalate synthase (NCBI) 0.98 3
Escherichia coli BL21 0.54 ECD_00075 3-isopropylmalate dehydrogenase, NAD(+)-dependent 0.09 ECD_00076 2-isopropylmalate synthase 0.79 11
Escherichia coli ECRC62 0.54 BNILDI_08545 leuA 2-isopropylmalate synthase 0.09 BNILDI_08550 2-isopropylmalate synthase — —
Enterobacter asburiae PDN3 0.54 EX28DRAFT_3669 3-isopropylmalate dehydrogenase 0.57 EX28DRAFT_2770 2-isopropylmalate synthase, yeast type low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.54 OHPLBJKB_03584 3-isopropylmalate dehydrogenase 0.09 OHPLBJKB_03583 2-isopropylmalate synthase low > 73
Escherichia coli ECOR27 0.54 NOLOHH_03065 leuA 2-isopropylmalate synthase 0.09 NOLOHH_03060 2-isopropylmalate synthase low > 57
Serratia liquefaciens MT49 0.53 IAI46_03350 3-isopropylmalate dehydrogenase 0.58 IAI46_09630 2-isopropylmalate synthase low > 86
Shewanella loihica PV-4 0.53 Shew_3471 3-isopropylmalate dehydrogenase (RefSeq) 0.10 Shew_3472 2-isopropylmalate synthase (RefSeq) 0.99 2
Rahnella sp. WP5 0.53 EX31_RS03685 3-isopropylmalate dehydrogenase 0.57 EX31_RS24130 2-isopropylmalate synthase low > 89
Bosea sp. OAE506 0.53 ABIE41_RS11860 3-isopropylmalate dehydrogenase 0.11 ABIE41_RS13000 2-isopropylmalate synthase — —
Klebsiella michiganensis M5al 0.53 BWI76_RS04675 3-isopropylmalate dehydrogenase 0.55 BWI76_RS22105 2-isopropylmalate synthase low > 92
Rhodopseudomonas palustris CGA009 0.53 TX73_001175 3-isopropylmalate dehydrogenase 0.58 TX73_024250 2-isopropylmalate synthase — —
Shewanella sp. ANA-3 0.53 Shewana3_3760 3-isopropylmalate dehydrogenase (RefSeq) 0.10 Shewana3_3761 2-isopropylmalate synthase (RefSeq) 0.98 2
Vibrio cholerae E7946 ATCC 55056 0.53 CSW01_12600 3-isopropylmalate dehydrogenase 0.11 CSW01_12595 2-isopropylmalate synthase low > 62
Shewanella oneidensis MR-1 0.53 SO4235 leuB 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.10 SO4236 leuA 2-isopropylmalate synthase (NCBI ptt file) 0.99 1
Shewanella amazonensis SB2B 0.52 Sama_0336 3-isopropylmalate dehydrogenase (RefSeq) 0.10 Sama_0335 2-isopropylmalate synthase (RefSeq) 0.97 8
Dickeya dianthicola ME23 0.52 DZA65_RS19205 3-isopropylmalate dehydrogenase 0.11 DZA65_RS19200 2-isopropylmalate synthase 0.97 2
Pectobacterium carotovorum WPP14 0.52 HER17_RS03080 3-isopropylmalate dehydrogenase 0.09 HER17_RS03085 2-isopropylmalate synthase 0.98 3
Dickeya dadantii 3937 0.52 DDA3937_RS18120 3-isopropylmalate dehydrogenase 0.52 DDA3937_RS02895 2-isopropylmalate synthase low > 74
Dickeya dianthicola 67-19 0.52 HGI48_RS18060 3-isopropylmalate dehydrogenase 0.11 HGI48_RS18055 2-isopropylmalate synthase 0.95 1
Caulobacter crescentus NA1000 Δfur 0.51 CCNA_00193 3-isopropylmalate dehydrogenase 0.11 CCNA_01610 2-isopropylmalate synthase low > 67
Caulobacter crescentus NA1000 0.51 CCNA_00193 3-isopropylmalate dehydrogenase 0.11 CCNA_01610 2-isopropylmalate synthase low > 66
Alteromonas macleodii MIT1002 0.51 MIT1002_00948 3-isopropylmalate dehydrogenase 0.11 MIT1002_00949 2-isopropylmalate synthase 0.99 2
Pantoea sp. MT58 0.50 IAI47_16005 3-isopropylmalate dehydrogenase 0.53 IAI47_10235 2-isopropylmalate synthase low > 76
Erwinia tracheiphila SCR3 0.50 LU632_RS02875 leuB 3-isopropylmalate dehydrogenase 0.10 LU632_RS02880 leuA 2-isopropylmalate synthase 0.95 3
Lysobacter sp. OAE881 0.49 ABIE51_RS17585 3-isopropylmalate dehydrogenase 0.10 ABIE51_RS17570 2-isopropylmalate synthase 0.86 61
Rhodanobacter denitrificans FW104-10B01 0.45 LRK54_RS10325 3-isopropylmalate dehydrogenase 0.10 LRK54_RS10345 2-isopropylmalate synthase 0.94 5
Rhodanobacter denitrificans MT42 0.45 LRK55_RS09965 3-isopropylmalate dehydrogenase 0.10 LRK55_RS09985 2-isopropylmalate synthase low > 63
Rhodanobacter sp. FW510-T8 0.45 OKGIIK_13595 leuB 3-isopropylmalate dehydrogenase 0.09 OKGIIK_13575 leuA 2-isopropylmalate synthase low > 52
Parabacteroides merdae CL09T00C40 0.45 HMPREF1078_RS16640 3-isopropylmalate dehydrogenase 0.13 HMPREF1078_RS16665 2-isopropylmalate synthase 0.98 4
Bacteroides stercoris CC31F 0.44 HMPREF1181_RS14125 3-isopropylmalate dehydrogenase 0.11 HMPREF1181_RS14150 2-isopropylmalate synthase 0.96 2
Bacteroides thetaiotaomicron VPI-5482 0.43 BT1857 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.11 BT1861 2-isopropylmalate synthase (EC 2.3.3.13) (from data) 0.89 16
Phocaeicola vulgatus CL09T03C04 0.43 HMPREF1058_RS14565 3-isopropylmalate dehydrogenase 0.11 HMPREF1058_RS14545 2-isopropylmalate synthase 0.72 36
Phocaeicola dorei CL03T12C01 0.43 ABI39_RS10215 3-isopropylmalate dehydrogenase 0.11 ABI39_RS10195 2-isopropylmalate synthase 0.86 8
Bacteroides ovatus ATCC 8483 0.42 BACOVA_04600 3-isopropylmalate dehydrogenase 0.11 BACOVA_04604 2-isopropylmalate synthase 0.96 9
Dyella japonica UNC79MFTsu3.2 0.42 ABZR86_RS15950 3-isopropylmalate dehydrogenase 0.09 ABZR86_RS15970 2-isopropylmalate synthase 0.97 3
Methanococcus maripaludis JJ 0.29 MMJJ_RS02220 3-isopropylmalate dehydrogenase 0.09 MMJJ_RS08870 2-isopropylmalate synthase — —
Methanococcus maripaludis S2 0.28 MMP_RS02855 3-isopropylmalate dehydrogenase 0.09 MMP_RS05500 2-isopropylmalate synthase — —
Mycobacterium tuberculosis H37Rv 0.27 Rv2995c Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) 0.52 Rv3710 2-isopropylmalate synthase LeuA (alpha-isopropylmalate synthase) (alpha-IPM synthetase) (IPMS) — —
Bifidobacterium breve UCC2003 0.25 BBR_RS12870 3-isopropylmalate dehydrogenase 0.50 BBR_RS11170 2-isopropylmalate synthase low > 34

Not shown: 7 genomes with orthologs for PP_1988 only; 0 genomes with orthologs for PP_1025 only