| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Pseudomonas putida KT2440 | 1.0 | PP_1985 | | 3-isopropylmalate dehydratase large subunit | 1.0 | PP_0966 | | Histidinol dehydrogenase | 0.90 | 4 |
| Pseudomonas fluorescens FW300-N1B4 | 0.90 | Pf1N1B4_15 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.92 | Pf1N1B4_1066 | | Histidinol dehydrogenase (EC 1.1.1.23) | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.90 | PfGW456L13_3948 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.91 | PfGW456L13_5000 | | Histidinol dehydrogenase (EC 1.1.1.23) | 0.91 | 18 |
| Pseudomonas fluorescens FW300-N2E2 | 0.89 | Pf6N2E2_63 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.90 | Pf6N2E2_3252 | | Histidinol dehydrogenase (EC 1.1.1.23) | 0.72 | 30 |
| Pseudomonas fluorescens FW300-N2E3 | 0.89 | AO353_20620 | | isopropylmalate isomerase | 0.92 | AO353_05110 | | histidinol dehydrogenase | 0.91 | 16 |
| Pseudomonas fluorescens FW300-N2C3 | 0.89 | AO356_21400 | | isopropylmalate isomerase | 0.90 | AO356_06965 | | histidinol dehydrogenase | 0.87 | 31 |
| Pseudomonas simiae WCS417 | 0.89 | PS417_18600 | | isopropylmalate isomerase | 0.91 | PS417_04420 | | histidinol dehydrogenase | 0.87 | 14 |
| Pseudomonas sp. RS175 | 0.89 | PFR28_02824 | | 3-isopropylmalate dehydratase large subunit | 0.90 | PFR28_00187 | | Histidinol dehydrogenase | 0.75 | 5 |
| Pseudomonas fluorescens SBW25 | 0.89 | PFLU_RS20580 | | 3-isopropylmalate dehydratase large subunit | 0.92 | PFLU_RS04470 | | histidinol dehydrogenase | 0.70 | 16 |
| Pseudomonas fluorescens SBW25-INTG | 0.89 | PFLU_RS20580 | | 3-isopropylmalate dehydratase large subunit | 0.92 | PFLU_RS04470 | | histidinol dehydrogenase | 0.84 | 13 |
| Pseudomonas stutzeri RCH2 | 0.88 | Psest_2591 | | 3-isopropylmalate dehydratase, large subunit | 0.85 | Psest_3298 | | histidinol dehydrogenase | 0.92 | 6 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.87 | Psyr_1983 | | 3-isopropylmalate dehydratase, large subunit | 0.89 | Psyr_4133 | | histidinol dehydrogenase | 0.90 | 15 |
| Pseudomonas syringae pv. syringae B728a | 0.87 | Psyr_1983 | | 3-isopropylmalate dehydratase, large subunit | 0.89 | Psyr_4133 | | histidinol dehydrogenase | 0.88 | 16 |
| Pseudomonas sp. S08-1 | 0.86 | OH686_04480 | | 3-isopropylmalate dehydratase large subunit | 0.85 | OH686_08470 | | Histidinol dehydrogenase | 0.83 | 16 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.84 | Xcc-8004.1049.1 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.35 | Xcc-8004.2948.1 | | Histidinol dehydrogenase (EC 1.1.1.23) | 0.91 | 11 |
| Marinobacter adhaerens HP15 | 0.78 | HP15_1834 | | protein containing 3-isopropylmalate dehydratase, large subunit region domain | 0.70 | HP15_2428 | | histidinol dehydrogenase | 0.87 | 15 |
| Kangiella aquimarina DSM 16071 | 0.76 | B158DRAFT_1319 | | 3-isopropylmalate dehydratase, large subunit | 0.28 | B158DRAFT_2293 | | histidinol dehydrogenase | low | > 40 |
| Acinetobacter radioresistens SK82 | 0.72 | MPMX26_00345 | | 3-isopropylmalate dehydratase large subunit | 0.57 | MPMX26_02587 | | Histidinol dehydrogenase | 0.90 | 23 |
| Ralstonia sp. UNC404CL21Col | 0.72 | ABZR87_RS14540 | | 3-isopropylmalate dehydratase large subunit | 0.62 | ABZR87_RS02500 | | histidinol dehydrogenase | — | — |
| Castellaniella sp019104865 MT123 | 0.72 | ABCV34_RS04290 | | 3-isopropylmalate dehydratase large subunit | 0.56 | ABCV34_RS11230 | | histidinol dehydrogenase | 0.48 | 17 |
| Cupriavidus basilensis FW507-4G11 | 0.72 | RR42_RS14400 | | isopropylmalate isomerase | 0.66 | RR42_RS18915 | | histidinol dehydrogenase | — | — |
| Ralstonia solanacearum PSI07 | 0.72 | RPSI07_RS14695 | | 3-isopropylmalate dehydratase large subunit | 0.63 | RPSI07_RS10390 | | histidinol dehydrogenase | — | — |
| Ralstonia solanacearum GMI1000 | 0.72 | RS_RS10000 | | 3-isopropylmalate dehydratase large subunit | 0.62 | RS_RS14790 | | histidinol dehydrogenase | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.71 | RALBFv3_RS02620 | | 3-isopropylmalate dehydratase large subunit | 0.62 | RALBFv3_RS06845 | | histidinol dehydrogenase | — | — |
| Ralstonia solanacearum UW163 | 0.71 | UW163_RS11105 | | 3-isopropylmalate dehydratase large subunit | 0.62 | UW163_RS06770 | | histidinol dehydrogenase | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.71 | H281DRAFT_06075 | | 3-isopropylmalate dehydratase, large subunit | 0.62 | H281DRAFT_05652 | | histidinol dehydrogenase | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.71 | QEN71_RS17605 | | 3-isopropylmalate dehydratase large subunit | 0.62 | QEN71_RS27865 | | histidinol dehydrogenase | 0.77 | 38 |
| Burkholderia phytofirmans PsJN | 0.71 | BPHYT_RS33915 | | isopropylmalate isomerase | 0.63 | BPHYT_RS17710 | | histidinol dehydrogenase | — | — |
| Herbaspirillum seropedicae SmR1 | 0.71 | HSERO_RS16515 | | isopropylmalate isomerase | 0.63 | HSERO_RS20345 | | histidinol dehydrogenase | 0.89 | 23 |
| Paraburkholderia graminis OAS925 | 0.71 | ABIE53_004801 | | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit | 0.62 | ABIE53_003701 | | histidinol dehydrogenase | — | — |
| Variovorax sp. OAS795 | 0.69 | ABID97_RS08465 | | 3-isopropylmalate dehydratase large subunit | 0.64 | ABID97_RS23160 | | histidinol dehydrogenase | — | — |
| Variovorax sp. SCN45 | 0.68 | GFF3890 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.64 | GFF5345 | | Histidinol dehydrogenase (EC 1.1.1.23) | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.67 | GFF3363 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.62 | GFF1314 | | Histidinol dehydrogenase (EC 1.1.1.23) | — | — |
| Acidovorax sp. GW101-3H11 | 0.67 | Ac3H11_1525 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.63 | Ac3H11_4724 | | Histidinol dehydrogenase (EC 1.1.1.23) | — | — |
| Azospirillum sp. SherDot2 | 0.66 | MPMX19_01998 | | 3-isopropylmalate dehydratase large subunit | 0.44 | MPMX19_05543 | | Histidinol dehydrogenase | — | — |
| Rhodospirillum rubrum S1H | 0.66 | Rru_A1189 | | 3-isopropylmalate dehydratase large subunit region (NCBI) | 0.47 | Rru_A2771 | | Histidinol dehydrogenase (NCBI) | 0.59 | 48 |
| Dechlorosoma suillum PS | 0.66 | Dsui_3201 | | 3-isopropylmalate dehydratase, large subunit | 0.63 | Dsui_1411 | | histidinol dehydrogenase | — | — |
| Sinorhizobium meliloti 1021 | 0.65 | SMc03823 | | isopropylmalate isomerase large subunit | 0.47 | SMc02307 | | histidinol dehydrogenase | 0.86 | 58 |
| Agrobacterium fabrum C58 | 0.64 | Atu2709 | | 3-isopropylmalate dehydratase, large subunit | 0.44 | Atu0537 | | histidinol dehydrogenase | 0.90 | 24 |
| Rhizobium sp. OAE497 | 0.63 | ABIE40_RS18380 | | 3-isopropylmalate dehydratase large subunit | 0.45 | ABIE40_RS02725 | | histidinol dehydrogenase | 0.95 | 17 |
| Bosea sp. OAE506 | 0.63 | ABIE41_RS11660 | | 3-isopropylmalate dehydratase large subunit | 0.45 | ABIE41_RS24015 | | histidinol dehydrogenase | — | — |
| Magnetospirillum magneticum AMB-1 | 0.63 | AMB_RS20560 | | 3-isopropylmalate dehydratase large subunit | 0.46 | AMB_RS16905 | | histidinol dehydrogenase | — | — |
| Rhodopseudomonas palustris CGA009 | 0.62 | TX73_001245 | | 3-isopropylmalate dehydratase large subunit | 0.43 | TX73_023540 | | histidinol dehydrogenase | — | — |
| Rahnella sp. WP5 | 0.62 | EX31_RS03690 | | 3-isopropylmalate dehydratase large subunit | 0.32 | EX31_RS11440 | | histidinol dehydrogenase | 0.97 | 29 |
| Pectobacterium carotovorum WPP14 | 0.61 | HER17_RS03075 | | 3-isopropylmalate dehydratase large subunit | 0.31 | HER17_RS12230 | | histidinol dehydrogenase | 0.96 | 27 |
| Caulobacter crescentus NA1000 Δfur | 0.61 | CCNA_00196 | | 3-isopropylmalate dehydratase large subunit | 0.38 | CCNA_02431 | | histidinol dehydrogenase | low | > 67 |
| Enterobacter asburiae PDN3 | 0.61 | EX28DRAFT_3668 | | 3-isopropylmalate dehydratase, large subunit | 0.31 | EX28DRAFT_0539 | | histidinol dehydrogenase | 0.90 | 16 |
| Caulobacter crescentus NA1000 | 0.61 | CCNA_00196 | | 3-isopropylmalate dehydratase large subunit | 0.38 | CCNA_02431 | | histidinol dehydrogenase | 0.96 | 11 |
| Pantoea sp. MT58 | 0.61 | IAI47_16010 | | 3-isopropylmalate dehydratase large subunit | 0.30 | IAI47_07090 | | histidinol dehydrogenase | 0.98 | 8 |
| Escherichia coli ECRC101 | 0.61 | MCAODC_01240 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.32 | MCAODC_20425 | hisD | Histidinol dehydrogenase | — | — |
| Escherichia coli Nissle 1917 | 0.61 | ECOLIN_RS00390 | | 3-isopropylmalate dehydratase large subunit | 0.32 | ECOLIN_RS11945 | | histidinol dehydrogenase | — | — |
| Enterobacter sp. TBS_079 | 0.61 | MPMX20_00767 | | 3-isopropylmalate dehydratase large subunit 1 | 0.31 | MPMX20_03002 | | Histidinol dehydrogenase | 0.94 | 12 |
| Escherichia coli ECRC98 | 0.61 | JDDGAC_14320 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.32 | JDDGAC_28625 | hisD | Histidinol dehydrogenase | — | — |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.61 | GFF166 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.32 | GFF3912 | | Histidinol dehydrogenase (EC 1.1.1.23) | low | > 78 |
| Escherichia coli BW25113 | 0.61 | b0072 | leuC | isopropylmalate isomerase large subunit (NCBI) | 0.32 | b2020 | hisD | histidinol dehydrogenase (NCBI) | 0.96 | 9 |
| Escherichia coli ECOR38 | 0.61 | HEPCGN_08705 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.32 | HEPCGN_03220 | hisD | Histidinol dehydrogenase | low | > 85 |
| Escherichia coli ECRC62 | 0.61 | BNILDI_08540 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.31 | BNILDI_14740 | hisD | Histidinol dehydrogenase | — | — |
| Escherichia coli ECOR27 | 0.61 | NOLOHH_03070 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.32 | NOLOHH_15830 | hisD | Histidinol dehydrogenase | low | > 57 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.61 | OHPLBJKB_03585 | | 3-isopropylmalate dehydratase large subunit | 0.32 | OHPLBJKB_01680 | | Histidinol dehydrogenase | low | > 73 |
| Escherichia coli BL21 | 0.61 | ECD_00074 | | 3-isopropylmalate dehydratase large subunit | 0.32 | ECD_01922 | | bifunctional histidinal dehydrogenase/ histidinol dehydrogenase | low | > 60 |
| Escherichia coli ECRC101 | 0.61 | OKFHMN_10725 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.32 | OKFHMN_24515 | hisD | Histidinol dehydrogenase | — | — |
| Escherichia coli ECRC102 | 0.61 | NIAGMN_08575 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.32 | NIAGMN_22460 | hisD | Histidinol dehydrogenase | — | — |
| Escherichia coli ECRC99 | 0.61 | KEDOAH_17430 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.32 | KEDOAH_03635 | hisD | Histidinol dehydrogenase | — | — |
| Klebsiella michiganensis M5al | 0.60 | BWI76_RS04670 | | 3-isopropylmalate dehydratase large subunit | 0.31 | BWI76_RS18925 | | histidinol dehydrogenase | 0.88 | 33 |
| Escherichia fergusonii Becca | 0.60 | EFB2_03973 | | 3-isopropylmalate dehydratase large subunit | 0.32 | EFB2_01836 | | Histidinol dehydrogenase | low | > 86 |
| Rhodanobacter denitrificans MT42 | 0.60 | LRK55_RS07105 | | 3-isopropylmalate dehydratase large subunit | 0.31 | LRK55_RS01385 | | histidinol dehydrogenase | low | > 63 |
| Dickeya dadantii 3937 | 0.60 | DDA3937_RS18125 | | 3-isopropylmalate dehydratase large subunit | 0.33 | DDA3937_RS09735 | | histidinol dehydrogenase | 0.70 | 37 |
| Dickeya dianthicola 67-19 | 0.60 | HGI48_RS18065 | | 3-isopropylmalate dehydratase large subunit | 0.32 | HGI48_RS09745 | | histidinol dehydrogenase | low | > 71 |
| Rhodanobacter denitrificans FW104-10B01 | 0.60 | LRK54_RS07375 | | 3-isopropylmalate dehydratase large subunit | 0.31 | LRK54_RS01605 | | histidinol dehydrogenase | low | > 59 |
| Dickeya dianthicola ME23 | 0.60 | DZA65_RS19210 | | 3-isopropylmalate dehydratase large subunit | 0.32 | DZA65_RS10055 | | histidinol dehydrogenase | 0.68 | 49 |
| Shewanella loihica PV-4 | 0.59 | Shew_3470 | | isopropylmalate isomerase large subunit (RefSeq) | 0.33 | Shew_2198 | | histidinol dehydrogenase (RefSeq) | 0.94 | 33 |
| Shewanella oneidensis MR-1 | 0.59 | SO4234 | leuC | 3-isopropylmalate dehydratase, large subunit (NCBI ptt file) | 0.32 | SO2073 | hisD | histidinol dehydrogenase (NCBI ptt file) | 0.98 | 11 |
| Phaeobacter inhibens DSM 17395 | 0.59 | PGA1_c29780 | | 3-isopropylmalate dehydratase large subunit | 0.46 | PGA1_c31190 | | histidinol dehydrogenase HisD | — | — |
| Shewanella sp. ANA-3 | 0.59 | Shewana3_3759 | | isopropylmalate isomerase large subunit (RefSeq) | 0.33 | Shewana3_1853 | hisD | histidinol dehydrogenase (RefSeq) | 0.94 | 15 |
| Dinoroseobacter shibae DFL-12 | 0.59 | Dshi_0085 | | 3-isopropylmalate dehydratase, large subunit (RefSeq) | 0.45 | Dshi_0979 | | Histidinol dehydrogenase (RefSeq) | — | — |
| Serratia liquefaciens MT49 | 0.59 | IAI46_03345 | | 3-isopropylmalate dehydratase large subunit | 0.30 | IAI46_08210 | | histidinol dehydrogenase | low | > 86 |
| Shewanella amazonensis SB2B | 0.59 | Sama_0337 | | isopropylmalate isomerase large subunit (RefSeq) | 0.33 | Sama_1942 | hisD | histidinol dehydrogenase (RefSeq) | 0.93 | 32 |
| Sphingomonas koreensis DSMZ 15582 | 0.58 | Ga0059261_4223 | | 3-isopropylmalate dehydratase, large subunit | 0.44 | Ga0059261_1281 | | histidinol dehydrogenase | 0.97 | 27 |
| Vibrio cholerae E7946 ATCC 55056 | 0.58 | CSW01_12605 | | 3-isopropylmalate dehydratase large subunit | 0.34 | CSW01_05750 | | histidinol dehydrogenase | low | > 62 |
| Alteromonas macleodii MIT1002 | 0.58 | MIT1002_00947 | | 3-isopropylmalate dehydratase large subunit | 0.32 | MIT1002_02633 | | Histidinol dehydrogenase | 0.97 | 35 |
| Mycobacterium tuberculosis H37Rv | 0.56 | Rv2988c | | Probable 3-isopropylmalate dehydratase (large subunit) LeuC (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI) | 0.28 | Rv1599 | | Probable histidinol dehydrogenase HisD (HDH) | — | — |
| Erwinia tracheiphila SCR3 | 0.56 | LU632_RS02870 | leuC | 3-isopropylmalate dehydratase large subunit | 0.31 | LU632_RS08945 | hisD | histidinol dehydrogenase | 0.74 | 38 |
| Bifidobacterium breve UCC2003 | 0.54 | BBR_RS19630 | | 3-isopropylmalate dehydratase large subunit | 0.31 | BBR_RS17055 | | histidinol dehydrogenase | low | > 34 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.52 | CA264_09435 | | 3-isopropylmalate dehydratase large subunit | 0.29 | CA264_05030 | | histidinol dehydrogenase | low | > 74 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.52 | ABZR88_RS11595 | | 3-isopropylmalate dehydratase large subunit | 0.32 | ABZR88_RS06880 | | histidinol dehydrogenase | — | — |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.51 | CA265_RS15830 | | 3-isopropylmalate dehydratase large subunit | 0.33 | CA265_RS03635 | | histidinol dehydrogenase | 0.91 | 32 |
| Parabacteroides merdae CL09T00C40 | 0.50 | HMPREF1078_RS16660 | | 3-isopropylmalate dehydratase large subunit | 0.31 | HMPREF1078_RS02450 | | histidinol dehydrogenase | 0.95 | 32 |
| Bacteroides stercoris CC31F | 0.50 | HMPREF1181_RS14145 | | 3-isopropylmalate dehydratase large subunit | 0.29 | HMPREF1181_RS04860 | | histidinol dehydrogenase | 0.93 | 14 |
| Phocaeicola dorei CL03T12C01 | 0.50 | ABI39_RS10200 | | 3-isopropylmalate dehydratase large subunit | 0.29 | ABI39_RS11835 | | histidinol dehydrogenase | 0.79 | 36 |
| Phocaeicola vulgatus CL09T03C04 | 0.50 | HMPREF1058_RS14550 | | 3-isopropylmalate dehydratase large subunit | 0.29 | HMPREF1058_RS15875 | | histidinol dehydrogenase | 0.81 | 19 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.49 | BT1860 | | 3-isopropylmalate dehydratase large subunit (NCBI ptt file) | 0.28 | BT0201 | | histidinol dehydrogenase (NCBI ptt file) | 0.88 | 19 |
| Bacteroides ovatus ATCC 8483 | 0.49 | BACOVA_04603 | | 3-isopropylmalate dehydratase, large subunit | 0.28 | BACOVA_01234 | | histidinol dehydrogenase | 0.95 | 16 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.49 | Echvi_2059 | | 3-isopropylmalate dehydratase, large subunit | 0.30 | Echvi_2459 | | histidinol dehydrogenase | 0.67 | 36 |
| Dyella japonica UNC79MFTsu3.2 | 0.48 | ABZR86_RS15960 | | 3-isopropylmalate dehydratase large subunit | 0.31 | ABZR86_RS06730 | | histidinol dehydrogenase | 0.95 | 22 |
| Lysobacter sp. OAE881 | 0.48 | ABIE51_RS17575 | | 3-isopropylmalate dehydratase large subunit | 0.32 | ABIE51_RS13325 | | histidinol dehydrogenase | 0.94 | 13 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.48 | A4249_RS10005 | | 3-isopropylmalate dehydratase large subunit | 0.28 | A4249_RS10695 | | histidinol dehydrogenase | 0.99 | 13 |
| Rhodanobacter sp. FW510-T8 | 0.47 | OKGIIK_13585 | leuC | 3-isopropylmalate dehydratase large subunit | 0.32 | OKGIIK_04950 | hisD | histidinol dehydrogenase | low | > 52 |
| Synechococcus elongatus PCC 7942 | 0.46 | Synpcc7942_1898 | leuC | isopropylmalate isomerase large subunit | 0.42 | Synpcc7942_1519 | hisD | histidinol dehydrogenase | — | — |
| Methanococcus maripaludis JJ | 0.22 | MMJJ_RS06750 | | homoaconitase large subunit | 0.35 | MMJJ_RS00120 | | histidinol dehydrogenase | — | — |
| Methanococcus maripaludis S2 | 0.22 | MMP_RS07610 | | homoaconitase large subunit | 0.35 | MMP_RS05015 | | histidinol dehydrogenase | — | — |
| Desulfovibrio vulgaris Miyazaki F | 0.20 | DvMF_1792 | | 3-isopropylmalate dehydratase large subunit (RefSeq) | 0.39 | DvMF_2814 | hisD | histidinol dehydrogenase (RefSeq) | 0.96 | 13 |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.20 | DVU2982 | leuC | 3-isopropylmalate dehydratase / (R)-citramalate isomerase, large subunit LeuC (EC 4.2.1.33; EC 4.2.1.35) (from data) | 0.41 | DVU0796 | hisD | histidinol dehydrogenase (TIGR) | 0.83 | 35 |
Not shown: 1 genomes with orthologs for PP_1985 only; 0 genomes with orthologs for PP_0966 only