Conservation of cofitness between CSW01_02215 and CSW01_12605 in Vibrio cholerae E7946 ATCC 55056

102 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_02215 carbon-nitrogen hydrolase family protein 1.0 CSW01_12605 3-isopropylmalate dehydratase large subunit 0.71 2
Serratia liquefaciens MT49 0.49 IAI46_22690 carbon-nitrogen hydrolase family protein 0.79 IAI46_03345 3-isopropylmalate dehydratase large subunit low > 87
Pseudomonas sp. S08-1 0.45 OH686_08585 Uncharacterized subgroup of the nitrilase superfamily 0.62 OH686_04480 3-isopropylmalate dehydratase large subunit low > 80
Shewanella oneidensis MR-1 0.44 SO4092 hydrolase, carbon-nitrogen family (NCBI ptt file) 0.72 SO4234 leuC 3-isopropylmalate dehydratase, large subunit (NCBI ptt file) low > 76
Pseudomonas aeruginosa PA14 0.43 IKLFDK_01705 carbon-nitrogen hydrolase 0.61 IKLFDK_15880 3-isopropylmalate dehydratase large subunit low > 98
Pseudomonas aeruginosa PUPa3 0.43 DQ20_RS56560 carbon-nitrogen hydrolase family protein 0.61 DQ20_RS34235 leuC;go_component=3-isopropylmalate 3-isopropylmalate dehydratase large subunit low > 101
Pseudomonas aeruginosa MRSN321 0.43 DY961_RS24100 carbon-nitrogen hydrolase family protein 0.61 DY961_RS01320 leuC;go_component=3-isopropylmalate 3-isopropylmalate dehydratase large subunit low > 100
Shewanella loihica PV-4 0.43 Shew_0409 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase (RefSeq) 0.71 Shew_3470 isopropylmalate isomerase large subunit (RefSeq) low > 60
Pseudomonas segetis P6 0.42 MPMX49_03866 Deaminated glutathione amidase 0.60 MPMX49_03074 3-isopropylmalate dehydratase large subunit low > 75
Shewanella sp. ANA-3 0.42 Shewana3_3642 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase (RefSeq) 0.72 Shewana3_3759 isopropylmalate isomerase large subunit (RefSeq) low > 73
Pseudomonas sp. SVBP6 0.42 COO64_RS04220 carbon-nitrogen hydrolase family protein 0.60 COO64_RS05665 leuC 3-isopropylmalate dehydratase large subunit low > 93
Pseudomonas fluorescens GW456-L13 0.42 PfGW456L13_5027 FIG003879: Predicted amidohydrolase / Omega amidase (Nit2 homolog) 0.61 PfGW456L13_3948 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) low > 87
Pseudomonas syringae pv. syringae B728a 0.42 Psyr_4157 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase 0.62 Psyr_1983 3-isopropylmalate dehydratase, large subunit low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.42 Psyr_4157 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase 0.62 Psyr_1983 3-isopropylmalate dehydratase, large subunit low > 86
Pseudomonas sp. RS175 0.42 PFR28_00160 Deaminated glutathione amidase 0.61 PFR28_02824 3-isopropylmalate dehydratase large subunit low > 88
Pseudomonas simiae WCS417 0.42 PS417_04280 carbon-nitrogen hydrolase 0.62 PS417_18600 isopropylmalate isomerase low > 88
Pseudomonas sp. DMC3 0.42 GFF1815 Deaminated glutathione amidase 0.61 GFF785 3-isopropylmalate dehydratase large subunit low > 89
Pseudomonas fluorescens SBW25-INTG 0.41 PFLU_RS04335 carbon-nitrogen hydrolase family protein 0.61 PFLU_RS20580 3-isopropylmalate dehydratase large subunit low > 109
Pseudomonas fluorescens SBW25 0.41 PFLU_RS04335 carbon-nitrogen hydrolase family protein 0.61 PFLU_RS20580 3-isopropylmalate dehydratase large subunit low > 109
Pseudomonas fluorescens FW300-N2E3 0.41 AO353_05220 carbon-nitrogen hydrolase 0.61 AO353_20620 isopropylmalate isomerase low > 101
Pseudomonas stutzeri RCH2 0.41 Psest_3321 Predicted amidohydrolase 0.62 Psest_2591 3-isopropylmalate dehydratase, large subunit low > 67
Shewanella amazonensis SB2B 0.41 Sama_0473 carbon-nitrogen family hydrolase (RefSeq) 0.72 Sama_0337 isopropylmalate isomerase large subunit (RefSeq) low > 62
Pseudomonas fluorescens FW300-N2C3 0.41 AO356_07100 carbon-nitrogen hydrolase 0.61 AO356_21400 isopropylmalate isomerase low > 104
Pseudomonas putida KT2440 0.41 PP_0939 Carbon-nitrogen hydrolase family protein 0.61 PP_1985 3-isopropylmalate dehydratase large subunit low > 96
Pseudomonas fluorescens FW300-N2E2 0.41 Pf6N2E2_3281 FIG003879: Predicted amidohydrolase / Omega amidase (Nit2 homolog) 0.61 Pf6N2E2_63 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) low > 103
Pseudomonas lactucae CFBP13502 0.41 GEMAOFIL_01061 Deaminated glutathione amidase 0.61 GEMAOFIL_03948 3-isopropylmalate dehydratase large subunit low > 96
Pseudomonas fluorescens FW300-N1B4 0.41 Pf1N1B4_1093 FIG003879: Predicted amidohydrolase / Omega amidase (Nit2 homolog) 0.61 Pf1N1B4_15 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) low > 87
Pseudomonas orientalis W4I3 0.40 QF045_RS07270 carbon-nitrogen hydrolase family protein 0.62 QF045_RS20740 3-isopropylmalate dehydratase large subunit low > 93
Azospirillum brasilense Sp245 0.40 AZOBR_RS02920 amidohydrolase 0.64 AZOBR_RS03545 isopropylmalate isomerase low > 97
Azospirillum sp. SherDot2 0.40 MPMX19_02429 Deaminated glutathione amidase 0.65 MPMX19_01998 3-isopropylmalate dehydratase large subunit low > 112
Pseudomonas sp. BP01 0.40 JOY50_RS11065 carbon-nitrogen hydrolase family protein 0.61 JOY50_RS16630 leuC 3-isopropylmalate dehydratase large subunit low > 84
Phaeobacter inhibens DSM 17395 0.39 PGA1_c34700 putative carbon-nitrogen hydrolase 0.59 PGA1_c29780 3-isopropylmalate dehydratase large subunit low > 62
Alteromonas macleodii MIT1002 0.38 MIT1002_00226 (R)-stereoselective amidase 0.67 MIT1002_00947 3-isopropylmalate dehydratase large subunit low > 70
Marinobacter adhaerens HP15 0.38 HP15_2449 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase 0.62 HP15_1834 protein containing 3-isopropylmalate dehydratase, large subunit region domain low > 73
Paraburkholderia sabiae LMG 24235 0.38 QEN71_RS26550 carbon-nitrogen hydrolase family protein 0.62 QEN71_RS17605 3-isopropylmalate dehydratase large subunit low > 153
Dinoroseobacter shibae DFL-12 0.38 Dshi_3506 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase (RefSeq) 0.58 Dshi_0085 3-isopropylmalate dehydratase, large subunit (RefSeq) low > 64
Paraburkholderia graminis OAS925 0.38 ABIE53_000852 putative amidohydrolase 0.62 ABIE53_004801 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit low > 113
Burkholderia phytofirmans PsJN 0.38 BPHYT_RS03545 apolipoprotein acyltransferase 0.62 BPHYT_RS33915 isopropylmalate isomerase low > 109
Methylophilus sp. DMC18 0.37 GFF381 Deaminated glutathione amidase 0.62 GFF646 3-isopropylmalate dehydratase large subunit
Paraburkholderia bryophila 376MFSha3.1 0.37 H281DRAFT_04689 nitrilase 0.62 H281DRAFT_06075 3-isopropylmalate dehydratase, large subunit low > 103
Dechlorosoma suillum PS 0.36 Dsui_3402 putative amidohydrolase 0.57 Dsui_3201 3-isopropylmalate dehydratase, large subunit
Sphingomonas koreensis DSMZ 15582 0.36 Ga0059261_3603 Predicted amidohydrolase 0.56 Ga0059261_4223 3-isopropylmalate dehydratase, large subunit 0.40 50
Sinorhizobium meliloti 1021 0.36 SMc02442 hydrolase 0.63 SMc03823 isopropylmalate isomerase large subunit low > 103
Herbaspirillum seropedicae SmR1 0.36 HSERO_RS07150 apolipoprotein acyltransferase 0.61 HSERO_RS16515 isopropylmalate isomerase low > 78
Rhodopseudomonas palustris CGA009 0.36 TX73_003100 carbon-nitrogen hydrolase family protein 0.61 TX73_001245 3-isopropylmalate dehydratase large subunit
Cupriavidus basilensis FW507-4G11 0.36 RR42_RS05880 acyltransferase 0.62 RR42_RS14400 isopropylmalate isomerase low > 128
Synechococcus elongatus PCC 7942 0.36 Synpcc7942_2358 nitrilase-like 0.51 Synpcc7942_1898 leuC isopropylmalate isomerase large subunit
Ralstonia solanacearum GMI1000 0.36 RS_RS13310 carbon-nitrogen hydrolase family protein 0.62 RS_RS10000 3-isopropylmalate dehydratase large subunit low > 80
Synechocystis sp000284455 PCC 6803 0.36 SGL_RS14360 carbon-nitrogen hydrolase family protein 0.50 SGL_RS17620 3-isopropylmalate dehydratase large subunit
Brevundimonas sp. GW460-12-10-14-LB2 0.35 A4249_RS13565 carbon-nitrogen hydrolase family protein 0.52 A4249_RS10005 3-isopropylmalate dehydratase large subunit low > 48
Ralstonia solanacearum IBSBF1503 0.35 RALBFv3_RS05450 carbon-nitrogen hydrolase family protein 0.61 RALBFv3_RS02620 3-isopropylmalate dehydratase large subunit low > 76
Ralstonia solanacearum PSI07 0.35 RPSI07_RS11855 carbon-nitrogen hydrolase family protein 0.62 RPSI07_RS14695 3-isopropylmalate dehydratase large subunit low > 81
Ralstonia solanacearum UW163 0.35 UW163_RS08175 carbon-nitrogen hydrolase family protein 0.61 UW163_RS11105 3-isopropylmalate dehydratase large subunit
Acinetobacter baumannii LAC-4 0.35 RR41_RS15875 carbon-nitrogen hydrolase family protein 0.61 RR41_RS16900 3-isopropylmalate dehydratase large subunit low > 55
Variovorax sp. SCN45 0.35 GFF5445 FIG003879: Uncharacterized subgroup of the nitrilase superfamily 0.61 GFF3890 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) low > 127
Caulobacter crescentus NA1000 Δfur 0.35 CCNA_00871 carbon-nitrogen hydrolase family protein 0.60 CCNA_00196 3-isopropylmalate dehydratase large subunit low > 67
Variovorax sp. OAS795 0.35 ABID97_RS02000 carbon-nitrogen hydrolase family protein 0.61 ABID97_RS08465 3-isopropylmalate dehydratase large subunit
Caulobacter crescentus NA1000 0.35 CCNA_00871 carbon-nitrogen hydrolase family protein 0.60 CCNA_00196 3-isopropylmalate dehydratase large subunit low > 66
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS01100 carbon-nitrogen hydrolase family protein 0.62 ABZR87_RS14540 3-isopropylmalate dehydratase large subunit low > 80
Rhodospirillum rubrum S1H 0.34 Rru_A0739 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase (NCBI) 0.64 Rru_A1189 3-isopropylmalate dehydratase large subunit region (NCBI) low > 58
Sphingobium sp. HT1-2 0.34 GFF2532 FIG147869: Carbon-nitrogen hydrolase 0.56 GFF2630 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) low > 95
Agrobacterium fabrum C58 0.34 Atu3510 amidohydrolase 0.62 Atu2709 3-isopropylmalate dehydratase, large subunit low > 89
Rhizobium sp. OAE497 0.34 ABIE40_RS17345 carbon-nitrogen hydrolase family protein 0.61 ABIE40_RS18380 3-isopropylmalate dehydratase large subunit low > 107
Magnetospirillum magneticum AMB-1 0.34 AMB_RS08115 carbon-nitrogen hydrolase family protein 0.63 AMB_RS20560 3-isopropylmalate dehydratase large subunit
Acinetobacter radioresistens SK82 0.33 MPMX26_00580 Deaminated glutathione amidase 0.61 MPMX26_00345 3-isopropylmalate dehydratase large subunit low > 36
Xanthobacter sp. DMC5 0.33 GFF102 Deaminated glutathione amidase 0.59 GFF1852 3-isopropylmalate dehydratase large subunit
Castellaniella sp019104865 MT123 0.33 ABCV34_RS02585 carbon-nitrogen hydrolase family protein 0.61 ABCV34_RS04290 3-isopropylmalate dehydratase large subunit low > 48
Kangiella aquimarina DSM 16071 0.32 B158DRAFT_2071 Predicted amidohydrolase 0.62 B158DRAFT_1319 3-isopropylmalate dehydratase, large subunit low > 40
Hydrogenophaga sp. GW460-11-11-14-LB1 0.31 GFF2535 FIG003879: Predicted amidohydrolase 0.60 GFF3363 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) low > 90
Acidovorax sp. GW101-3H11 0.29 Ac3H11_1207 FIG003879: Predicted amidohydrolase 0.60 Ac3H11_1525 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) low > 79
Pantoea agglomerans CFBP13505 P0401 0.20 PagCFBP13505_RS03225 deaminated glutathione amidase 0.81 PagCFBP13505_RS12990 3-isopropylmalate dehydratase large subunit low > 74
Mycobacterium tuberculosis H37Rv 0.20 Rv0480c Possible amidohydrolase 0.58 Rv2988c Probable 3-isopropylmalate dehydratase (large subunit) LeuC (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI)
Dickeya dianthicola 67-19 0.19 HGI48_RS19475 deaminated glutathione amidase 0.80 HGI48_RS18065 3-isopropylmalate dehydratase large subunit low > 71
Klebsiella michiganensis M5al 0.19 BWI76_RS07990 carbon-nitrogen hydrolase 0.81 BWI76_RS04670 3-isopropylmalate dehydratase large subunit
Klebsiella pneumoniae MKP103 0.19 KDGMDA_16350 deaminated glutathione amidase 0.81 KDGMDA_12900 3-isopropylmalate dehydratase large subunit 1 low > 95
Erwinia amylovora T8 0.19 OLJFJH_17270 deaminated glutathione amidase 0.74 OLJFJH_01295 3-isopropylmalate dehydratase large subunit low > 58
Pantoea sp. MT58 0.19 IAI47_14065 deaminated glutathione amidase 0.81 IAI47_16010 3-isopropylmalate dehydratase large subunit low > 76
Dickeya dadantii 3937 0.18 DDA3937_RS06130 deaminated glutathione amidase 0.79 DDA3937_RS18125 3-isopropylmalate dehydratase large subunit low > 74
Erwinia tracheiphila SCR3 0.18 LU632_RS16420 deaminated glutathione amidase 0.75 LU632_RS02870 leuC 3-isopropylmalate dehydratase large subunit low > 73
Dickeya dianthicola ME23 0.18 DZA65_RS06520 deaminated glutathione amidase 0.80 DZA65_RS19210 3-isopropylmalate dehydratase large subunit low > 75
Erwinia tracheiphila HP pepo 2.2 0.18 IJEDHG_02515 deaminated glutathione amidase 0.75 IJEDHG_06005 leuC 3-isopropylmalate dehydratase large subunit low > 61
Enterobacter asburiae PDN3 0.18 EX28DRAFT_2337 Predicted amidohydrolase 0.82 EX28DRAFT_3668 3-isopropylmalate dehydratase, large subunit low > 76
Rahnella sp. WP5 0.17 EX31_RS23065 deaminated glutathione amidase 0.80 EX31_RS03690 3-isopropylmalate dehydratase large subunit low > 89
Enterobacter sp. TBS_079 0.17 MPMX20_01285 Deaminated glutathione amidase 0.81 MPMX20_00767 3-isopropylmalate dehydratase large subunit 1 low > 85
Pectobacterium carotovorum WPP14 0.17 HER17_RS17575 deaminated glutathione amidase 0.80 HER17_RS03075 3-isopropylmalate dehydratase large subunit low > 75
Phocaeicola vulgatus CL09T03C04 0.17 HMPREF1058_RS04375 carbon-nitrogen hydrolase 0.50 HMPREF1058_RS14550 3-isopropylmalate dehydratase large subunit low > 67
Phocaeicola dorei CL03T12C01 0.17 ABI39_RS16695 carbon-nitrogen hydrolase 0.51 ABI39_RS10200 3-isopropylmalate dehydratase large subunit low > 72
Parabacteroides merdae CL09T00C40 0.16 HMPREF1078_RS01170 carbon-nitrogen hydrolase 0.51 HMPREF1078_RS16660 3-isopropylmalate dehydratase large subunit low > 61
Xanthomonas campestris pv. campestris strain 8004 0.16 Xcc-8004.2374.1 N-carbamoylputrescine amidase (3.5.1.53) / Aliphatic amidase AmiE (EC 3.5.1.4) 0.62 Xcc-8004.1049.1 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Bacteroides thetaiotaomicron VPI-5482 0.16 BT0875 beta-ureidopropionase (NCBI ptt file) 0.51 BT1860 3-isopropylmalate dehydratase large subunit (NCBI ptt file) low > 81
Bacteroides stercoris CC31F 0.15 HMPREF1181_RS14235 carbon-nitrogen hydrolase 0.51 HMPREF1181_RS14145 3-isopropylmalate dehydratase large subunit low > 56
Pedobacter sp. GW460-11-11-14-LB5 0.15 CA265_RS15465 acyltransferase 0.58 CA265_RS15830 3-isopropylmalate dehydratase large subunit
Bacteroides ovatus ATCC 8483 0.15 BACOVA_02592 hydrolase, carbon-nitrogen family 0.51 BACOVA_04603 3-isopropylmalate dehydratase, large subunit low > 96
Rhodanobacter sp000427505 FW510-R12 0.15 LRK53_RS09305 amidohydrolase 0.52 LRK53_RS03110 3-isopropylmalate dehydratase large subunit low > 59
Mucilaginibacter yixingensis YX-36 DSM 26809 0.15 ABZR88_RS18075 carbon-nitrogen hydrolase 0.59 ABZR88_RS11595 3-isopropylmalate dehydratase large subunit
Rhodanobacter denitrificans FW104-10B01 0.14 LRK54_RS00825 amidohydrolase 0.54 LRK54_RS07375 3-isopropylmalate dehydratase large subunit low > 59
Rhodanobacter denitrificans MT42 0.14 LRK55_RS00600 amidohydrolase 0.54 LRK55_RS07105 3-isopropylmalate dehydratase large subunit low > 63
Lysobacter sp. OAE881 0.14 ABIE51_RS09320 carbon-nitrogen hydrolase 0.52 ABIE51_RS17575 3-isopropylmalate dehydratase large subunit
Rhodanobacter sp. FW510-T8 0.14 OKGIIK_06395 nit2 amidohydrolase 0.50 OKGIIK_13585 leuC 3-isopropylmalate dehydratase large subunit 0.63 8
Bosea sp. OAE506 0.14 ABIE41_RS12325 N-carbamoyl-D-amino-acid hydrolase 0.61 ABIE41_RS11660 3-isopropylmalate dehydratase large subunit
Dyella japonica UNC79MFTsu3.2 0.13 ABZR86_RS02765 carbon-nitrogen hydrolase 0.52 ABZR86_RS15960 3-isopropylmalate dehydratase large subunit
Echinicola vietnamensis KMM 6221, DSM 17526 0.12 Echvi_1887 Predicted amidohydrolase 0.54 Echvi_2059 3-isopropylmalate dehydratase, large subunit low > 79
Desulfovibrio vulgaris Miyazaki F 0.11 DvMF_0653 N-carbamoylputrescine amidase (RefSeq) 0.21 DvMF_1792 3-isopropylmalate dehydratase large subunit (RefSeq) low > 51

Not shown: 0 genomes with orthologs for CSW01_02215 only; 20 genomes with orthologs for CSW01_12605 only