| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Agrobacterium fabrum C58 | 1.0 | Atu3755 | | phosphoribosylaminoimidazole carboxylase ATPase subunit | 1.0 | Atu2264 | | 2-isopropylmalate synthase | 0.91 | 8 |
| Rhizobium sp. OAE497 | 0.69 | ABIE40_RS16070 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.87 | ABIE40_RS13330 | | 2-isopropylmalate synthase | 0.88 | 11 |
| Sinorhizobium meliloti 1021 | 0.66 | SMc04002 | | phosphoribosylaminoimidazole carboxylase ATPase subunit | 0.88 | SMc02717 | | 2-isopropylmalate synthase | 0.94 | 20 |
| Dinoroseobacter shibae DFL-12 | 0.48 | Dshi_0680 | | phosphoribosylaminoimidazole carboxylase, ATPase subunit (RefSeq) | 0.12 | Dshi_0596 | | 2-isopropylmalate synthase (RefSeq) | 0.76 | 14 |
| Phaeobacter inhibens DSM 17395 | 0.46 | PGA1_c24870 | | phosphoribosylaminoimidazole carboxylase ATPase subunit PurK | 0.11 | PGA1_c26470 | | 2-isopropylmalate synthase LeuA | 0.86 | 19 |
| Caulobacter crescentus NA1000 Δfur | 0.45 | CCNA_03392 | | phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit | 0.10 | CCNA_01610 | | 2-isopropylmalate synthase | low | > 67 |
| Caulobacter crescentus NA1000 | 0.45 | CCNA_03392 | | phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit | 0.10 | CCNA_01610 | | 2-isopropylmalate synthase | low | > 66 |
| Azospirillum brasilense Sp245 | 0.42 | AZOBR_RS06140 | | phosphoribosylaminoimidazole carboxylase | 0.58 | AZOBR_RS12155 | | 2-isopropylmalate synthase | — | — |
| Bosea sp. OAE506 | 0.42 | ABIE41_RS09245 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.11 | ABIE41_RS13000 | | 2-isopropylmalate synthase | low | > 77 |
| Rhodopseudomonas palustris CGA009 | 0.42 | TX73_021645 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.50 | TX73_024250 | | 2-isopropylmalate synthase | — | — |
| Herbaspirillum seropedicae SmR1 | 0.40 | HSERO_RS03370 | | phosphoribosylaminoimidazole carboxylase | 0.52 | HSERO_RS17185 | | 2-isopropylmalate synthase | — | — |
| Rhodospirillum rubrum S1H | 0.40 | Rru_A1051 | | Phosphoribosylaminoimidazole carboxylase, ATPase subunit (NCBI) | 0.59 | Rru_A1928 | | Yeast 2-isopropylmalate synthase (NCBI) | low | > 58 |
| Azospirillum sp. SherDot2 | 0.39 | MPMX19_01418 | | N5-carboxyaminoimidazole ribonucleotide synthase | 0.59 | MPMX19_01822 | | 2-isopropylmalate synthase | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.39 | Ga0059261_1428 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.51 | Ga0059261_4031 | | 2-isopropylmalate synthase, yeast type | — | — |
| Pseudomonas sp. S08-1 | 0.38 | OH686_13380 | | N5-carboxyaminoimidazole ribonucleotide synthase | 0.52 | OH686_17570 | | 2-isopropylmalate synthase | — | — |
| Pseudomonas stutzeri RCH2 | 0.38 | Psest_4068 | | phosphoribosylaminoimidazole carboxylase, PurK protein | 0.55 | Psest_1277 | | 2-isopropylmalate synthase, yeast type | — | — |
| Magnetospirillum magneticum AMB-1 | 0.38 | AMB_RS11140 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.55 | AMB_RS17550 | | 2-isopropylmalate synthase | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.38 | Pf6N2E2_4081 | | Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) | 0.53 | Pf6N2E2_3170 | | 2-isopropylmalate synthase (EC 2.3.3.13) | — | — |
| Acinetobacter radioresistens SK82 | 0.38 | MPMX26_03050 | | N5-carboxyaminoimidazole ribonucleotide synthase | 0.50 | MPMX26_00404 | | 2-isopropylmalate synthase | low | > 36 |
| Pseudomonas sp. RS175 | 0.38 | PFR28_04495 | | N5-carboxyaminoimidazole ribonucleotide synthase | 0.53 | PFR28_00305 | | 2-isopropylmalate synthase | — | — |
| Pseudomonas putida KT2440 | 0.38 | PP_5335 | | N5-carboxyaminoimidazole ribonucleotide synthase | 0.54 | PP_1025 | | 2-isopropylmalate synthase | — | — |
| Paraburkholderia graminis OAS925 | 0.37 | ABIE53_003423 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.50 | ABIE53_002867 | | 2-isopropylmalate synthase | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.37 | H281DRAFT_04185 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.51 | H281DRAFT_00385 | | 2-isopropylmalate synthase | — | — |
| Lysobacter sp. OAE881 | 0.37 | ABIE51_RS15390 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.11 | ABIE51_RS17570 | | 2-isopropylmalate synthase | low | > 62 |
| Burkholderia phytofirmans PsJN | 0.37 | BPHYT_RS16245 | | phosphoribosylaminoimidazole carboxylase | 0.50 | BPHYT_RS13280 | | 2-isopropylmalate synthase | low | > 109 |
| Pseudomonas fluorescens FW300-N2C3 | 0.37 | AO356_11075 | | phosphoribosylaminoimidazole carboxylase | 0.53 | AO356_06550 | | 2-isopropylmalate synthase | — | — |
| Rhodanobacter sp. FW510-T8 | 0.36 | OKGIIK_03050 | purK | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.10 | OKGIIK_13575 | leuA | 2-isopropylmalate synthase | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.36 | PfGW456L13_747 | | Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) | 0.52 | PfGW456L13_4854 | | 2-isopropylmalate synthase (EC 2.3.3.13) | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.36 | Pf1N1B4_2028 | | Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) | 0.53 | Pf1N1B4_847 | | 2-isopropylmalate synthase (EC 2.3.3.13) | — | — |
| Xanthomonas campestris pv. campestris strain 8004 | 0.36 | Xcc-8004.2012.1 | | Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) | 0.11 | Xcc-8004.1056.1 | | 2-isopropylmalate synthase (EC 2.3.3.13) | 0.69 | 42 |
| Variovorax sp. SCN45 | 0.36 | GFF5513 | | N5-carboxyaminoimidazole ribonucleotide synthase (EC 6.3.4.18) | 0.50 | GFF1164 | | 2-isopropylmalate synthase (EC 2.3.3.13) | 0.89 | 38 |
| Pseudomonas fluorescens SBW25 | 0.36 | PFLU_RS29800 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.53 | PFLU_RS24765 | | 2-isopropylmalate synthase | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.36 | AO353_09935 | | phosphoribosylaminoimidazole carboxylase | 0.53 | AO353_15925 | | 2-isopropylmalate synthase | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.36 | PFLU_RS29800 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.53 | PFLU_RS24765 | | 2-isopropylmalate synthase | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.36 | Psyr_5047 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.53 | Psyr_1257 | | 2-isopropylmalate synthase | — | — |
| Pseudomonas simiae WCS417 | 0.36 | PS417_28115 | | phosphoribosylaminoimidazole carboxylase | 0.53 | PS417_23110 | | 2-isopropylmalate synthase | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.36 | Psyr_5047 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.53 | Psyr_1257 | | 2-isopropylmalate synthase | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.35 | RR42_RS03230 | | phosphoribosylaminoimidazole carboxylase | 0.49 | RR42_RS21205 | | 2-isopropylmalate synthase | — | — |
| Rhodanobacter denitrificans FW104-10B01 | 0.35 | LRK54_RS13815 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.10 | LRK54_RS10345 | | 2-isopropylmalate synthase | — | — |
| Rhodanobacter denitrificans MT42 | 0.34 | LRK55_RS13530 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.10 | LRK55_RS09985 | | 2-isopropylmalate synthase | low | > 63 |
| Variovorax sp. OAS795 | 0.34 | ABID97_RS01700 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.50 | ABID97_RS14905 | | 2-isopropylmalate synthase | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.34 | GFF2770 | | Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) | 0.50 | GFF4280 | | 2-isopropylmalate synthase (EC 2.3.3.13) | — | — |
| Castellaniella sp019104865 MT123 | 0.34 | ABCV34_RS00565 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.48 | ABCV34_RS12420 | | 2-isopropylmalate synthase | — | — |
| Marinobacter adhaerens HP15 | 0.34 | HP15_2350 | | phosphoribosylaminoimidazole carboxylase ATPase subunit | 0.48 | HP15_2055 | | 2-isopropylmalate synthase | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.33 | ABZR86_RS09830 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.11 | ABZR86_RS15970 | | 2-isopropylmalate synthase | — | — |
| Ralstonia sp. UNC404CL21Col | 0.32 | ABZR87_RS08090 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.52 | ABZR87_RS22365 | | 2-isopropylmalate synthase | — | — |
| Dechlorosoma suillum PS | 0.32 | Dsui_0091 | | phosphoribosylaminoimidazole carboxylase, PurK protein | 0.51 | Dsui_3227 | | 2-isopropylmalate synthase | — | — |
| Ralstonia solanacearum GMI1000 | 0.32 | RS_RS02885 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.51 | RS_RS18695 | | 2-isopropylmalate synthase 2 | — | — |
| Ralstonia solanacearum PSI07 | 0.32 | RPSI07_RS21130 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.52 | RPSI07_RS01320 | | 2-isopropylmalate synthase | — | — |
| Ralstonia solanacearum UW163 | 0.31 | UW163_RS01410 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.53 | UW163_RS17345 | | 2-isopropylmalate synthase | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.31 | RALBFv3_RS12200 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.53 | RALBFv3_RS21840 | | 2-isopropylmalate synthase | — | — |
| Acidovorax sp. GW101-3H11 | 0.31 | Ac3H11_675 | | Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) | 0.46 | Ac3H11_5000 | | 2-isopropylmalate synthase (EC 2.3.3.13) | — | — |
| Bifidobacterium breve UCC2003 | 0.31 | BBR_RS13300 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.50 | BBR_RS11170 | | 2-isopropylmalate synthase | low | > 34 |
| Synechococcus elongatus PCC 7942 | 0.30 | Synpcc7942_1428 | purK | phosphoribosylaminoimidazole carboxylase ATPase subunit | 0.09 | Synpcc7942_1410 | leuA | 2-isopropylmalate synthase | — | — |
| Vibrio cholerae E7946 ATCC 55056 | 0.28 | CSW01_00260 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.10 | CSW01_12595 | | 2-isopropylmalate synthase | low | > 62 |
| Pantoea sp. MT58 | 0.26 | IAI47_14355 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.44 | IAI47_10235 | | 2-isopropylmalate synthase | low | > 76 |
| Alteromonas macleodii MIT1002 | 0.26 | MIT1002_00522 | | N5-carboxyaminoimidazole ribonucleotide synthase | 0.09 | MIT1002_00949 | | 2-isopropylmalate synthase | 0.98 | 24 |
| Shewanella loihica PV-4 | 0.25 | Shew_1249 | | phosphoribosylaminoimidazole carboxylase, ATPase subunit (RefSeq) | 0.09 | Shew_3472 | | 2-isopropylmalate synthase (RefSeq) | 0.66 | 47 |
| Shewanella oneidensis MR-1 | 0.25 | SO3555 | purK | phosphoribosylaminoimidazole carboxylase, ATPase subunit (NCBI ptt file) | 0.09 | SO4236 | leuA | 2-isopropylmalate synthase (NCBI ptt file) | 0.86 | 43 |
| Mycobacterium tuberculosis H37Rv | 0.25 | Rv3276c | | Probable phosphoribosylaminoimidazole carboxylase ATPase subunit PurK (air carboxylase) (AIRC) | 0.52 | Rv3710 | | 2-isopropylmalate synthase LeuA (alpha-isopropylmalate synthase) (alpha-IPM synthetase) (IPMS) | — | — |
| Escherichia coli BL21 | 0.24 | ECD_00472 | | N5-carboxyaminoimidazole ribonucleotide synthase | 0.09 | ECD_00076 | | 2-isopropylmalate synthase | low | > 60 |
| Klebsiella michiganensis M5al | 0.24 | BWI76_RS07065 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.46 | BWI76_RS22105 | | 2-isopropylmalate synthase | low | > 92 |
| Escherichia coli BW25113 | 0.24 | b0522 | purK | phosphoribosylaminoimidazole carboxylase (NCBI) | 0.09 | b0074 | leuA | 2-isopropylmalate synthase (NCBI) | 0.76 | 57 |
| Escherichia coli ECRC98 | 0.24 | JDDGAC_11490 | purK | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.09 | JDDGAC_14310 | | 2-isopropylmalate synthase | — | — |
| Escherichia coli ECOR38 | 0.24 | HEPCGN_06480 | purK | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.09 | HEPCGN_08695 | | 2-isopropylmalate synthase | low | > 85 |
| Escherichia coli Nissle 1917 | 0.24 | ECOLIN_RS03025 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.09 | ECOLIN_RS00400 | | 2-isopropylmalate synthase | low | > 52 |
| Escherichia coli ECRC99 | 0.24 | KEDOAH_20130 | purK | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.09 | KEDOAH_17440 | | 2-isopropylmalate synthase | — | — |
| Escherichia coli ECRC102 | 0.24 | NIAGMN_05895 | purK | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.09 | NIAGMN_08565 | | 2-isopropylmalate synthase | — | — |
| Escherichia coli ECRC101 | 0.24 | OKFHMN_07840 | purK | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.09 | OKFHMN_10715 | | 2-isopropylmalate synthase | — | — |
| Escherichia coli ECRC101 | 0.24 | MCAODC_27060 | purK | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.09 | MCAODC_01230 | | 2-isopropylmalate synthase | — | — |
| Escherichia fergusonii Becca | 0.24 | EFB2_03540 | | N5-carboxyaminoimidazole ribonucleotide synthase | 0.09 | EFB2_03971 | | 2-isopropylmalate synthase | low | > 86 |
| Escherichia coli ECOR27 | 0.24 | NOLOHH_00830 | purK | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.09 | NOLOHH_03060 | | 2-isopropylmalate synthase | low | > 57 |
| Enterobacter sp. TBS_079 | 0.24 | MPMX20_01097 | | N5-carboxyaminoimidazole ribonucleotide synthase | 0.46 | MPMX20_03565 | | 2-isopropylmalate synthase | low | > 85 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.24 | OHPLBJKB_03159 | | N5-carboxyaminoimidazole ribonucleotide synthase | 0.09 | OHPLBJKB_03583 | | 2-isopropylmalate synthase | low | > 73 |
| Escherichia coli ECRC62 | 0.24 | BNILDI_22260 | purK | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.09 | BNILDI_08550 | | 2-isopropylmalate synthase | — | — |
| Dickeya dianthicola 67-19 | 0.24 | HGI48_RS15190 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.09 | HGI48_RS18055 | | 2-isopropylmalate synthase | 0.71 | 14 |
| Dickeya dadantii 3937 | 0.23 | DDA3937_RS15110 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.45 | DDA3937_RS02895 | | 2-isopropylmalate synthase | low | > 74 |
| Shewanella sp. ANA-3 | 0.23 | Shewana3_3156 | | phosphoribosylaminoimidazole carboxylase ATPase subunit (RefSeq) | 0.09 | Shewana3_3761 | | 2-isopropylmalate synthase (RefSeq) | 0.86 | 34 |
| Dickeya dianthicola ME23 | 0.23 | DZA65_RS15995 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.10 | DZA65_RS19200 | | 2-isopropylmalate synthase | 0.63 | 49 |
| Rahnella sp. WP5 | 0.23 | EX31_RS22620 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.50 | EX31_RS24130 | | 2-isopropylmalate synthase | low | > 89 |
| Enterobacter asburiae PDN3 | 0.23 | EX28DRAFT_2460 | | phosphoribosylaminoimidazole carboxylase, PurK protein | 0.46 | EX28DRAFT_2770 | | 2-isopropylmalate synthase, yeast type | — | — |
| Pectobacterium carotovorum WPP14 | 0.23 | HER17_RS06470 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.10 | HER17_RS03085 | | 2-isopropylmalate synthase | 0.97 | 2 |
| Shewanella amazonensis SB2B | 0.23 | Sama_1063 | | phosphoribosylaminoimidazole carboxylase ATPase subunit (RefSeq) | 0.09 | Sama_0335 | | 2-isopropylmalate synthase (RefSeq) | 0.79 | 62 |
| Erwinia tracheiphila SCR3 | 0.22 | LU632_RS15250 | purK | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.11 | LU632_RS02880 | leuA | 2-isopropylmalate synthase | low | > 74 |
| Serratia liquefaciens MT49 | 0.22 | IAI46_05370 | | 5-(carboxyamino)imidazole ribonucleotide synthase | 0.49 | IAI46_09630 | | 2-isopropylmalate synthase | low | > 86 |
| Methanococcus maripaludis S2 | 0.18 | MMP_RS00715 | | formate-dependent phosphoribosylglycinamide formyltransferase | 0.10 | MMP_RS05500 | | 2-isopropylmalate synthase | — | — |
| Methanococcus maripaludis JJ | 0.17 | MMJJ_RS04770 | | formate-dependent phosphoribosylglycinamide formyltransferase | 0.10 | MMJJ_RS08870 | | 2-isopropylmalate synthase | low | > 28 |
| Desulfovibrio vulgaris Miyazaki F | 0.16 | DvMF_2756 | purT | phosphoribosylglycinamide formyltransferase 2 (RefSeq) | 0.13 | DvMF_1791 | | 2-isopropylmalate synthase (RefSeq) | 0.33 | 17 |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.15 | DVU0723 | purT | phosphoribosylglycinamide formyltransferase 2 (TIGR) | 0.12 | DVU2981 | leuA | 2-isopropylmalate synthase (TIGR) | low | > 55 |
| Parabacteroides merdae CL09T00C40 | 0.15 | HMPREF1078_RS10980 | | formate-dependent phosphoribosylglycinamide formyltransferase | 0.12 | HMPREF1078_RS16665 | | 2-isopropylmalate synthase | low | > 61 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.15 | BT0704 | | phosphoribosylglycinamide formyltransferase 2 (NCBI ptt file) | 0.10 | BT1861 | | 2-isopropylmalate synthase (EC 2.3.3.13) (from data) | 0.24 | 13 |
| Bacteroides stercoris CC31F | 0.15 | HMPREF1181_RS16250 | | formate-dependent phosphoribosylglycinamide formyltransferase | 0.11 | HMPREF1181_RS14150 | | 2-isopropylmalate synthase | 0.46 | 54 |
| Bacteroides ovatus ATCC 8483 | 0.14 | BACOVA_02411 | | phosphoribosylglycinamide formyltransferase 2 | 0.10 | BACOVA_04604 | | 2-isopropylmalate synthase | low | > 94 |
| Phocaeicola dorei CL03T12C01 | 0.14 | ABI39_RS14185 | | formate-dependent phosphoribosylglycinamide formyltransferase | 0.10 | ABI39_RS10195 | | 2-isopropylmalate synthase | low | > 72 |
| Phocaeicola vulgatus CL09T03C04 | 0.14 | HMPREF1058_RS17920 | | formate-dependent phosphoribosylglycinamide formyltransferase | 0.10 | HMPREF1058_RS14545 | | 2-isopropylmalate synthase | low | > 67 |
Not shown: 8 genomes with orthologs for Atu3755 only; 0 genomes with orthologs for Atu2264 only