| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Agrobacterium fabrum C58 | 1.0 | Atu0041 | | glutamine amidotransferase | 1.0 | Atu2264 | | 2-isopropylmalate synthase | 0.80 | 20 |
| Rhizobium sp. OAE497 | 0.87 | ABIE40_RS19450 | | imidazole glycerol phosphate synthase subunit HisH | 0.87 | ABIE40_RS13330 | | 2-isopropylmalate synthase | 0.93 | 20 |
| Sinorhizobium meliloti 1021 | 0.80 | SMc02572 | | imidazole glycerol phosphate synthase subunit HisH | 0.88 | SMc02717 | | 2-isopropylmalate synthase | 0.86 | 22 |
| Bosea sp. OAE506 | 0.63 | ABIE41_RS03955 | | imidazole glycerol phosphate synthase subunit HisH | 0.11 | ABIE41_RS13000 | | 2-isopropylmalate synthase | low | > 77 |
| Rhodopseudomonas palustris CGA009 | 0.61 | TX73_001615 | | imidazole glycerol phosphate synthase subunit HisH | 0.50 | TX73_024250 | | 2-isopropylmalate synthase | — | — |
| Azospirillum sp. SherDot2 | 0.60 | MPMX19_02545 | | Imidazole glycerol phosphate synthase subunit HisH | 0.59 | MPMX19_01822 | | 2-isopropylmalate synthase | — | — |
| Azospirillum brasilense Sp245 | 0.55 | AZOBR_RS01670 | | imidazole glycerol phosphate synthase | 0.58 | AZOBR_RS12155 | | 2-isopropylmalate synthase | 0.87 | 18 |
| Dinoroseobacter shibae DFL-12 | 0.55 | Dshi_0795 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit (RefSeq) | 0.12 | Dshi_0596 | | 2-isopropylmalate synthase (RefSeq) | — | — |
| Rhodospirillum rubrum S1H | 0.55 | Rru_A3596 | | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit (NCBI) | 0.59 | Rru_A1928 | | Yeast 2-isopropylmalate synthase (NCBI) | 0.64 | 34 |
| Phaeobacter inhibens DSM 17395 | 0.53 | PGA1_c09320 | | imidazole glycerol phosphate synthase subunit HisH | 0.11 | PGA1_c26470 | | 2-isopropylmalate synthase LeuA | — | — |
| Magnetospirillum magneticum AMB-1 | 0.53 | AMB_RS22935 | | imidazole glycerol phosphate synthase subunit HisH | 0.55 | AMB_RS17550 | | 2-isopropylmalate synthase | — | — |
| Caulobacter crescentus NA1000 Δfur | 0.51 | CCNA_03851 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit | 0.10 | CCNA_01610 | | 2-isopropylmalate synthase | low | > 67 |
| Caulobacter crescentus NA1000 | 0.51 | CCNA_03851 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit | 0.10 | CCNA_01610 | | 2-isopropylmalate synthase | 0.82 | 66 |
| Sphingomonas koreensis DSMZ 15582 | 0.43 | Ga0059261_1046 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit | 0.51 | Ga0059261_4031 | | 2-isopropylmalate synthase, yeast type | 0.97 | 17 |
| Ralstonia solanacearum UW163 | 0.38 | UW163_RS06790 | | imidazole glycerol phosphate synthase subunit HisH | 0.53 | UW163_RS17345 | | 2-isopropylmalate synthase | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.38 | RALBFv3_RS06825 | | imidazole glycerol phosphate synthase subunit HisH | 0.53 | RALBFv3_RS21840 | | 2-isopropylmalate synthase | — | — |
| Ralstonia solanacearum PSI07 | 0.37 | RPSI07_RS10410 | | imidazole glycerol phosphate synthase subunit HisH | 0.52 | RPSI07_RS01320 | | 2-isopropylmalate synthase | — | — |
| Ralstonia solanacearum GMI1000 | 0.37 | RS_RS14770 | | imidazole glycerol phosphate synthase subunit HisH | 0.51 | RS_RS18695 | | 2-isopropylmalate synthase 2 | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.36 | RR42_RS18895 | | imidazole glycerol phosphate synthase | 0.49 | RR42_RS21205 | | 2-isopropylmalate synthase | — | — |
| Ralstonia sp. UNC404CL21Col | 0.36 | ABZR87_RS02480 | | imidazole glycerol phosphate synthase subunit HisH | 0.52 | ABZR87_RS22365 | | 2-isopropylmalate synthase | low | > 80 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.36 | H281DRAFT_05657 | | imidazole glycerol phosphate synthase subunit hisH | 0.51 | H281DRAFT_00385 | | 2-isopropylmalate synthase | — | — |
| Paraburkholderia graminis OAS925 | 0.36 | ABIE53_003697 | | glutamine amidotransferase | 0.50 | ABIE53_002867 | | 2-isopropylmalate synthase | — | — |
| Methanococcus maripaludis JJ | 0.36 | MMJJ_RS03990 | | imidazole glycerol phosphate synthase subunit HisH | 0.10 | MMJJ_RS08870 | | 2-isopropylmalate synthase | — | — |
| Variovorax sp. OAS795 | 0.36 | ABID97_RS23135 | | imidazole glycerol phosphate synthase subunit HisH | 0.50 | ABID97_RS14905 | | 2-isopropylmalate synthase | — | — |
| Burkholderia phytofirmans PsJN | 0.35 | BPHYT_RS17690 | | imidazole glycerol phosphate synthase | 0.50 | BPHYT_RS13280 | | 2-isopropylmalate synthase | low | > 109 |
| Methanococcus maripaludis S2 | 0.35 | MMP_RS01385 | | imidazole glycerol phosphate synthase subunit HisH | 0.10 | MMP_RS05500 | | 2-isopropylmalate synthase | low | > 25 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.35 | GFF1311 | | Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) | 0.50 | GFF4280 | | 2-isopropylmalate synthase (EC 2.3.3.13) | — | — |
| Variovorax sp. SCN45 | 0.35 | GFF5350 | | Imidazole glycerol phosphate synthase amidotransferase subunit HisH | 0.50 | GFF1164 | | 2-isopropylmalate synthase (EC 2.3.3.13) | — | — |
| Acinetobacter radioresistens SK82 | 0.35 | MPMX26_02846 | | Imidazole glycerol phosphate synthase subunit HisH | 0.50 | MPMX26_00404 | | 2-isopropylmalate synthase | low | > 36 |
| Herbaspirillum seropedicae SmR1 | 0.34 | HSERO_RS20325 | | IGP synthase, amidotransferase subunit (EC 4.3.2.10) (from data) | 0.52 | HSERO_RS17185 | | 2-isopropylmalate synthase | 0.81 | 13 |
| Acidovorax sp. GW101-3H11 | 0.34 | Ac3H11_4731 | | Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) | 0.46 | Ac3H11_5000 | | 2-isopropylmalate synthase (EC 2.3.3.13) | — | — |
| Marinobacter adhaerens HP15 | 0.34 | HP15_3011 | | imidazole glycerol phosphate synthase subunit HisH | 0.48 | HP15_2055 | | 2-isopropylmalate synthase | — | — |
| Dechlorosoma suillum PS | 0.32 | Dsui_1416 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit | 0.51 | Dsui_3227 | | 2-isopropylmalate synthase | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.31 | ABZR86_RS06715 | | imidazole glycerol phosphate synthase subunit HisH | 0.11 | ABZR86_RS15970 | | 2-isopropylmalate synthase | 0.95 | 18 |
| Castellaniella sp019104865 MT123 | 0.31 | ABCV34_RS11240 | | imidazole glycerol phosphate synthase subunit HisH | 0.48 | ABCV34_RS12420 | | 2-isopropylmalate synthase | 0.89 | 18 |
| Klebsiella michiganensis M5al | 0.30 | BWI76_RS18940 | | imidazole glycerol phosphate synthase subunit HisH | 0.46 | BWI76_RS22105 | | 2-isopropylmalate synthase | low | > 92 |
| Pseudomonas fluorescens FW300-N2C3 | 0.30 | AO356_03385 | | imidazole glycerol phosphate synthase subunit HisH | 0.53 | AO356_06550 | | 2-isopropylmalate synthase | low | > 104 |
| Pseudomonas sp. RS175 | 0.30 | PFR28_04930 | | Imidazole glycerol phosphate synthase subunit HisH | 0.53 | PFR28_00305 | | 2-isopropylmalate synthase | 0.68 | 13 |
| Enterobacter sp. TBS_079 | 0.30 | MPMX20_03005 | | Imidazole glycerol phosphate synthase subunit HisH | 0.46 | MPMX20_03565 | | 2-isopropylmalate synthase | low | > 85 |
| Serratia liquefaciens MT49 | 0.30 | IAI46_08195 | | imidazole glycerol phosphate synthase subunit HisH | 0.49 | IAI46_09630 | | 2-isopropylmalate synthase | low | > 86 |
| Pseudomonas fluorescens FW300-N1B4 | 0.29 | Pf1N1B4_1626 | | Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) | 0.53 | Pf1N1B4_847 | | 2-isopropylmalate synthase (EC 2.3.3.13) | 0.81 | 12 |
| Pseudomonas stutzeri RCH2 | 0.29 | Psest_0153 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit | 0.55 | Psest_1277 | | 2-isopropylmalate synthase, yeast type | 0.67 | 37 |
| Pseudomonas fluorescens GW456-L13 | 0.29 | PfGW456L13_361 | | Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) | 0.52 | PfGW456L13_4854 | | 2-isopropylmalate synthase (EC 2.3.3.13) | 0.87 | 22 |
| Vibrio cholerae E7946 ATCC 55056 | 0.29 | CSW01_05765 | | imidazole glycerol phosphate synthase subunit HisH | 0.10 | CSW01_12595 | | 2-isopropylmalate synthase | low | > 62 |
| Shewanella sp. ANA-3 | 0.29 | Shewana3_1850 | hisH | imidazole glycerol phosphate synthase subunit HisH (RefSeq) | 0.09 | Shewana3_3761 | | 2-isopropylmalate synthase (RefSeq) | 0.95 | 14 |
| Enterobacter asburiae PDN3 | 0.29 | EX28DRAFT_0536 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit | 0.46 | EX28DRAFT_2770 | | 2-isopropylmalate synthase, yeast type | low | > 76 |
| Escherichia coli ECRC98 | 0.29 | JDDGAC_28610 | hisH | imidazole glycerol phosphate synthase subunit HisH | 0.09 | JDDGAC_14310 | | 2-isopropylmalate synthase | — | — |
| Escherichia coli ECRC101 | 0.29 | OKFHMN_24500 | hisH | imidazole glycerol phosphate synthase subunit HisH | 0.09 | OKFHMN_10715 | | 2-isopropylmalate synthase | — | — |
| Escherichia coli ECRC101 | 0.29 | MCAODC_20440 | hisH | imidazole glycerol phosphate synthase subunit HisH | 0.09 | MCAODC_01230 | | 2-isopropylmalate synthase | — | — |
| Escherichia coli ECRC62 | 0.29 | BNILDI_14725 | hisH | imidazole glycerol phosphate synthase subunit HisH | 0.09 | BNILDI_08550 | | 2-isopropylmalate synthase | — | — |
| Escherichia coli ECOR38 | 0.29 | HEPCGN_03205 | hisH | imidazole glycerol phosphate synthase subunit HisH | 0.09 | HEPCGN_08695 | | 2-isopropylmalate synthase | low | > 85 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.29 | OHPLBJKB_01677 | | Imidazole glycerol phosphate synthase subunit HisH | 0.09 | OHPLBJKB_03583 | | 2-isopropylmalate synthase | low | > 73 |
| Escherichia coli ECRC99 | 0.29 | KEDOAH_03650 | hisH | imidazole glycerol phosphate synthase subunit HisH | 0.09 | KEDOAH_17440 | | 2-isopropylmalate synthase | — | — |
| Escherichia coli BW25113 | 0.29 | b2023 | hisH | imidazole glycerol phosphate synthase subunit HisH (NCBI) | 0.09 | b0074 | leuA | 2-isopropylmalate synthase (NCBI) | 0.93 | 11 |
| Escherichia coli Nissle 1917 | 0.29 | ECOLIN_RS11960 | | imidazole glycerol phosphate synthase subunit HisH | 0.09 | ECOLIN_RS00400 | | 2-isopropylmalate synthase | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.29 | Pf6N2E2_3841 | | Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) | 0.53 | Pf6N2E2_3170 | | 2-isopropylmalate synthase (EC 2.3.3.13) | 0.77 | 23 |
| Pseudomonas fluorescens FW300-N2E3 | 0.29 | AO353_12075 | | imidazole glycerol phosphate synthase subunit HisH | 0.53 | AO353_15925 | | 2-isopropylmalate synthase | 0.86 | 23 |
| Shewanella oneidensis MR-1 | 0.28 | SO2070 | hisH | amidotransferase HisH (NCBI ptt file) | 0.09 | SO4236 | leuA | 2-isopropylmalate synthase (NCBI ptt file) | 0.97 | 14 |
| Escherichia fergusonii Becca | 0.28 | EFB2_01833 | | Imidazole glycerol phosphate synthase subunit HisH | 0.09 | EFB2_03971 | | 2-isopropylmalate synthase | low | > 86 |
| Pseudomonas sp. S08-1 | 0.28 | OH686_14580 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit | 0.52 | OH686_17570 | | 2-isopropylmalate synthase | 0.69 | 41 |
| Escherichia coli ECOR27 | 0.28 | NOLOHH_15815 | hisH | imidazole glycerol phosphate synthase subunit HisH | 0.09 | NOLOHH_03060 | | 2-isopropylmalate synthase | low | > 57 |
| Dickeya dianthicola ME23 | 0.28 | DZA65_RS10040 | | imidazole glycerol phosphate synthase subunit HisH | 0.10 | DZA65_RS19200 | | 2-isopropylmalate synthase | — | — |
| Lysobacter sp. OAE881 | 0.28 | ABIE51_RS13310 | | imidazole glycerol phosphate synthase subunit HisH | 0.11 | ABIE51_RS17570 | | 2-isopropylmalate synthase | low | > 62 |
| Dickeya dianthicola 67-19 | 0.28 | HGI48_RS09730 | | imidazole glycerol phosphate synthase subunit HisH | 0.09 | HGI48_RS18055 | | 2-isopropylmalate synthase | 0.78 | 53 |
| Escherichia coli BL21 | 0.28 | ECD_01925 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit | 0.09 | ECD_00076 | | 2-isopropylmalate synthase | low | > 60 |
| Dickeya dadantii 3937 | 0.28 | DDA3937_RS09720 | | imidazole glycerol phosphate synthase subunit HisH | 0.45 | DDA3937_RS02895 | | 2-isopropylmalate synthase | low | > 74 |
| Erwinia tracheiphila SCR3 | 0.28 | LU632_RS08930 | hisH | imidazole glycerol phosphate synthase subunit HisH | 0.11 | LU632_RS02880 | leuA | 2-isopropylmalate synthase | 0.74 | 42 |
| Pseudomonas simiae WCS417 | 0.28 | PS417_01565 | | imidazole glycerol phosphate synthase | 0.53 | PS417_23110 | | 2-isopropylmalate synthase | 0.83 | 19 |
| Pseudomonas fluorescens SBW25 | 0.28 | PFLU_RS01610 | | imidazole glycerol phosphate synthase subunit HisH | 0.53 | PFLU_RS24765 | | 2-isopropylmalate synthase | 0.77 | 5 |
| Pseudomonas fluorescens SBW25-INTG | 0.28 | PFLU_RS01610 | | imidazole glycerol phosphate synthase subunit HisH | 0.53 | PFLU_RS24765 | | 2-isopropylmalate synthase | 0.68 | 3 |
| Pseudomonas putida KT2440 | 0.28 | PP_0290 | | Imidazole glycerol phosphate synthase subunit HisH | 0.54 | PP_1025 | | 2-isopropylmalate synthase | 0.81 | 28 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.28 | Psyr_4896 | | imidazole glycerol phosphate synthase subunit hisH | 0.53 | Psyr_1257 | | 2-isopropylmalate synthase | 0.85 | 15 |
| Escherichia coli ECRC102 | 0.28 | NIAGMN_22445 | hisH | imidazole glycerol phosphate synthase subunit HisH | 0.09 | NIAGMN_08565 | | 2-isopropylmalate synthase | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.28 | Psyr_4896 | | imidazole glycerol phosphate synthase subunit hisH | 0.53 | Psyr_1257 | | 2-isopropylmalate synthase | 0.88 | 11 |
| Pectobacterium carotovorum WPP14 | 0.27 | HER17_RS12245 | | imidazole glycerol phosphate synthase subunit HisH | 0.10 | HER17_RS03085 | | 2-isopropylmalate synthase | 0.96 | 11 |
| Shewanella loihica PV-4 | 0.27 | Shew_2201 | hisH | imidazole glycerol phosphate synthase subunit HisH (RefSeq) | 0.09 | Shew_3472 | | 2-isopropylmalate synthase (RefSeq) | 0.99 | 5 |
| Synechococcus elongatus PCC 7942 | 0.27 | Synpcc7942_1481 | hisH | imidazole glycerol phosphate synthase subunit HisH | 0.09 | Synpcc7942_1410 | leuA | 2-isopropylmalate synthase | — | — |
| Pantoea sp. MT58 | 0.27 | IAI47_07075 | | imidazole glycerol phosphate synthase subunit HisH | 0.44 | IAI47_10235 | | 2-isopropylmalate synthase | low | > 76 |
| Mycobacterium tuberculosis H37Rv | 0.27 | Rv1602 | | Probable amidotransferase HisH | 0.52 | Rv3710 | | 2-isopropylmalate synthase LeuA (alpha-isopropylmalate synthase) (alpha-IPM synthetase) (IPMS) | — | — |
| Rahnella sp. WP5 | 0.26 | EX31_RS11455 | | imidazole glycerol phosphate synthase subunit HisH | 0.50 | EX31_RS24130 | | 2-isopropylmalate synthase | low | > 89 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.26 | Xcc-8004.2945.1 | | Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) | 0.11 | Xcc-8004.1056.1 | | 2-isopropylmalate synthase (EC 2.3.3.13) | 0.82 | 17 |
| Rhodanobacter sp. FW510-T8 | 0.26 | OKGIIK_04965 | hisH | imidazole glycerol phosphate synthase subunit HisH | 0.10 | OKGIIK_13575 | leuA | 2-isopropylmalate synthase | low | > 52 |
| Rhodanobacter denitrificans MT42 | 0.26 | LRK55_RS01370 | | imidazole glycerol phosphate synthase subunit HisH | 0.10 | LRK55_RS09985 | | 2-isopropylmalate synthase | low | > 63 |
| Rhodanobacter denitrificans FW104-10B01 | 0.26 | LRK54_RS01590 | | imidazole glycerol phosphate synthase subunit HisH | 0.10 | LRK54_RS10345 | | 2-isopropylmalate synthase | low | > 59 |
| Bacteroides ovatus ATCC 8483 | 0.26 | BACOVA_00221 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit | 0.10 | BACOVA_04604 | | 2-isopropylmalate synthase | 0.81 | 51 |
| Parabacteroides merdae CL09T00C40 | 0.25 | HMPREF1078_RS13575 | | imidazole glycerol phosphate synthase subunit HisH | 0.12 | HMPREF1078_RS16665 | | 2-isopropylmalate synthase | 0.94 | 47 |
| Shewanella amazonensis SB2B | 0.25 | Sama_1945 | hisH | imidazole glycerol phosphate synthase subunit HisH (RefSeq) | 0.09 | Sama_0335 | | 2-isopropylmalate synthase (RefSeq) | 0.91 | 40 |
| Alteromonas macleodii MIT1002 | 0.25 | MIT1002_02636 | | Imidazole glycerol phosphate synthase subunit HisH | 0.09 | MIT1002_00949 | | 2-isopropylmalate synthase | 0.97 | 29 |
| Phocaeicola dorei CL03T12C01 | 0.25 | ABI39_RS19920 | | imidazole glycerol phosphate synthase subunit HisH | 0.10 | ABI39_RS10195 | | 2-isopropylmalate synthase | 0.67 | 33 |
| Phocaeicola vulgatus CL09T03C04 | 0.25 | HMPREF1058_RS06165 | | imidazole glycerol phosphate synthase subunit HisH | 0.10 | HMPREF1058_RS14545 | | 2-isopropylmalate synthase | 0.81 | 4 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.25 | BT1380 | | imidazole glycerol phosphate synthase subunit hisH (NCBI ptt file) | 0.10 | BT1861 | | 2-isopropylmalate synthase (EC 2.3.3.13) (from data) | 0.74 | 5 |
| Bacteroides stercoris CC31F | 0.24 | HMPREF1181_RS11080 | | imidazole glycerol phosphate synthase subunit HisH | 0.11 | HMPREF1181_RS14150 | | 2-isopropylmalate synthase | 0.82 | 13 |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.23 | DVU0285 | hisH | IGP synthase, amidotransferase subunit (EC 4.3.2.10) (from data) | 0.12 | DVU2981 | leuA | 2-isopropylmalate synthase (TIGR) | 0.88 | 22 |
| Bifidobacterium breve UCC2003 | 0.23 | BBR_RS17035 | | imidazole glycerol phosphate synthase subunit HisH | 0.50 | BBR_RS11170 | | 2-isopropylmalate synthase | low | > 34 |
| Desulfovibrio vulgaris Miyazaki F | 0.23 | DvMF_2305 | hisH | IGP synthase, amidotransferase subunit (EC 4.3.2.10) (from data) | 0.13 | DvMF_1791 | | 2-isopropylmalate synthase (RefSeq) | 0.90 | 22 |
Not shown: 8 genomes with orthologs for Atu0041 only; 0 genomes with orthologs for Atu2264 only