Conservation of cofitness between b2020 and b3771 in Escherichia coli BW25113

100 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2020 hisD histidinol dehydrogenase (NCBI) 1.0 b3771 ilvD dihydroxy-acid dehydratase (NCBI) 0.97 2
Escherichia coli ECOR27 0.99 NOLOHH_15830 hisD Histidinol dehydrogenase 1.00 NOLOHH_06775 ilvD dihydroxy-acid dehydratase 0.63 17
Escherichia coli BL21 0.99 ECD_01922 bifunctional histidinal dehydrogenase/ histidinol dehydrogenase 1.00 ECD_03649 dihydroxyacid dehydratase 0.29 55
Escherichia coli ECRC62 0.99 BNILDI_14740 hisD Histidinol dehydrogenase 1.00 BNILDI_04750 ilvD dihydroxy-acid dehydratase — —
Escherichia coli Nissle 1917 0.99 ECOLIN_RS11945 histidinol dehydrogenase 0.99 ECOLIN_RS21665 dihydroxy-acid dehydratase — —
Escherichia coli ECOR38 0.99 HEPCGN_03220 hisD Histidinol dehydrogenase 1.00 HEPCGN_13350 ilvD dihydroxy-acid dehydratase low > 85
Escherichia coli HS(pFamp)R (ATCC 700891) 0.98 OHPLBJKB_01680 Histidinol dehydrogenase 1.00 OHPLBJKB_04282 Dihydroxy-acid dehydratase low > 73
Escherichia fergusonii Becca 0.98 EFB2_01836 Histidinol dehydrogenase 0.99 EFB2_04865 Dihydroxy-acid dehydratase low > 86
Escherichia coli ECRC102 0.98 NIAGMN_22460 hisD Histidinol dehydrogenase 1.00 NIAGMN_12395 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC98 0.98 JDDGAC_28625 hisD Histidinol dehydrogenase 1.00 JDDGAC_18260 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC101 0.98 MCAODC_20425 hisD Histidinol dehydrogenase 1.00 MCAODC_05145 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC99 0.98 KEDOAH_03635 hisD Histidinol dehydrogenase 1.00 KEDOAH_13510 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC101 0.98 OKFHMN_24515 hisD Histidinol dehydrogenase 1.00 OKFHMN_14640 ilvD dihydroxy-acid dehydratase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF3912 Histidinol dehydrogenase (EC 1.1.1.23) 0.97 GFF2901 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 78
Enterobacter asburiae PDN3 0.89 EX28DRAFT_0539 histidinol dehydrogenase 0.96 EX28DRAFT_4443 dihydroxy-acid dehydratase 0.90 18
Enterobacter sp. TBS_079 0.89 MPMX20_03002 Histidinol dehydrogenase 0.97 MPMX20_04499 Dihydroxy-acid dehydratase 0.96 7
Klebsiella michiganensis M5al 0.88 BWI76_RS18925 histidinol dehydrogenase 0.96 BWI76_RS00975 dihydroxy-acid dehydratase 0.91 5
Serratia liquefaciens MT49 0.85 IAI46_08210 histidinol dehydrogenase 0.90 IAI46_24345 dihydroxy-acid dehydratase low > 86
Pantoea sp. MT58 0.82 IAI47_07090 histidinol dehydrogenase 0.89 IAI47_01035 dihydroxy-acid dehydratase 0.98 7
Erwinia tracheiphila SCR3 0.81 LU632_RS08945 hisD histidinol dehydrogenase 0.86 LU632_RS24400 ilvD dihydroxy-acid dehydratase low > 74
Dickeya dadantii 3937 0.80 DDA3937_RS09735 histidinol dehydrogenase 0.92 DDA3937_RS20155 dihydroxy-acid dehydratase 0.93 12
Pectobacterium carotovorum WPP14 0.80 HER17_RS12230 histidinol dehydrogenase 0.91 HER17_RS01075 dihydroxy-acid dehydratase 0.98 4
Dickeya dianthicola 67-19 0.79 HGI48_RS09745 histidinol dehydrogenase 0.91 HGI48_RS20295 dihydroxy-acid dehydratase low > 71
Rahnella sp. WP5 0.79 EX31_RS11440 histidinol dehydrogenase 0.87 EX31_RS15005 dihydroxy-acid dehydratase 0.96 13
Dickeya dianthicola ME23 0.79 DZA65_RS10055 histidinol dehydrogenase 0.91 DZA65_RS21335 dihydroxy-acid dehydratase 0.78 24
Vibrio cholerae E7946 ATCC 55056 0.63 CSW01_05750 histidinol dehydrogenase 0.85 CSW01_00140 dihydroxy-acid dehydratase low > 62
Shewanella amazonensis SB2B 0.59 Sama_1942 hisD histidinol dehydrogenase (RefSeq) 0.79 Sama_3279 dihydroxy-acid dehydratase (RefSeq) 0.97 7
Shewanella loihica PV-4 0.57 Shew_2198 histidinol dehydrogenase (RefSeq) 0.78 Shew_0292 dihydroxy-acid dehydratase (RefSeq) 0.93 17
Shewanella oneidensis MR-1 0.57 SO2073 hisD histidinol dehydrogenase (NCBI ptt file) 0.80 SO4345 ilvD dihydroxy-acid dehydratase (NCBI ptt file) 0.99 1
Shewanella sp. ANA-3 0.56 Shewana3_1853 hisD histidinol dehydrogenase (RefSeq) 0.80 Shewana3_0358 dihydroxy-acid dehydratase (RefSeq) 0.97 2
Alteromonas macleodii MIT1002 0.54 MIT1002_02633 Histidinol dehydrogenase 0.79 MIT1002_04041 Dihydroxy-acid dehydratase 0.97 20
Rhodanobacter denitrificans FW104-10B01 0.53 LRK54_RS01605 histidinol dehydrogenase 0.26 LRK54_RS10320 dihydroxy-acid dehydratase 0.69 29
Rhodanobacter denitrificans MT42 0.53 LRK55_RS01385 histidinol dehydrogenase 0.26 LRK55_RS09960 dihydroxy-acid dehydratase low > 63
Dyella japonica UNC79MFTsu3.2 0.53 ABZR86_RS06730 histidinol dehydrogenase 0.28 ABZR86_RS15945 dihydroxy-acid dehydratase 0.95 29
Rhodanobacter sp. FW510-T8 0.53 OKGIIK_04950 hisD histidinol dehydrogenase 0.27 OKGIIK_13600 ilvD dihydroxy-acid dehydratase low > 52
Bacteroides ovatus ATCC 8483 0.53 BACOVA_01234 histidinol dehydrogenase 0.62 BACOVA_03302 dihydroxy-acid dehydratase 0.95 23
Bacteroides thetaiotaomicron VPI-5482 0.52 BT0201 histidinol dehydrogenase (NCBI ptt file) 0.63 BT2078 dihydroxy-acid dehydratase (NCBI ptt file) 0.92 14
Phocaeicola vulgatus CL09T03C04 0.51 HMPREF1058_RS15875 histidinol dehydrogenase 0.64 HMPREF1058_RS16815 dihydroxy-acid dehydratase 0.89 23
Bacteroides stercoris CC31F 0.50 HMPREF1181_RS04860 histidinol dehydrogenase 0.64 HMPREF1181_RS08335 dihydroxy-acid dehydratase 0.86 41
Phocaeicola dorei CL03T12C01 0.50 ABI39_RS11835 histidinol dehydrogenase 0.64 ABI39_RS12715 dihydroxy-acid dehydratase 0.82 14
Lysobacter sp. OAE881 0.49 ABIE51_RS13325 histidinol dehydrogenase 0.27 ABIE51_RS17540 dihydroxy-acid dehydratase 0.97 26
Parabacteroides merdae CL09T00C40 0.48 HMPREF1078_RS02450 histidinol dehydrogenase 0.65 HMPREF1078_RS16695 dihydroxy-acid dehydratase low > 61
Xanthomonas campestris pv. campestris strain 8004 0.48 Xcc-8004.2948.1 Histidinol dehydrogenase (EC 1.1.1.23) 0.72 Xcc-8004.451.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.67 57
Echinicola vietnamensis KMM 6221, DSM 17526 0.47 Echvi_2459 histidinol dehydrogenase 0.29 Echvi_2055 dihydroxy-acid dehydratase 0.90 12
Pontibacter actiniarum KMM 6156, DSM 19842 0.45 CA264_05030 histidinol dehydrogenase 0.28 CA264_06935 dihydroxy-acid dehydratase low > 74
Pedobacter sp. GW460-11-11-14-LB5 0.44 CA265_RS03635 histidinol dehydrogenase 0.27 CA265_RS15795 dihydroxy-acid dehydratase 0.92 18
Mucilaginibacter yixingensis YX-36 DSM 26809 0.44 ABZR88_RS06880 histidinol dehydrogenase 0.27 ABZR88_RS11575 dihydroxy-acid dehydratase — —
Methanococcus maripaludis JJ 0.38 MMJJ_RS00120 histidinol dehydrogenase 0.35 MMJJ_RS03675 dihydroxy-acid dehydratase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.38 A4249_RS10695 histidinol dehydrogenase 0.25 A4249_RS10030 dihydroxy-acid dehydratase 1.00 2
Methanococcus maripaludis S2 0.37 MMP_RS05015 histidinol dehydrogenase 0.35 MMP_RS01700 dihydroxy-acid dehydratase — —
Sinorhizobium meliloti 1021 0.35 SMc02307 histidinol dehydrogenase 0.75 SMc04045 dihydroxy-acid dehydratase 0.88 7
Cupriavidus basilensis FW507-4G11 0.35 RR42_RS18915 histidinol dehydrogenase 0.29 RR42_RS16210 dihydroxy-acid dehydratase — —
Rhizobium sp. OAE497 0.34 ABIE40_RS02725 histidinol dehydrogenase 0.75 ABIE40_RS08005 dihydroxy-acid dehydratase 0.91 46
Pseudomonas sp. S08-1 0.34 OH686_08470 Histidinol dehydrogenase 0.75 OH686_14100 dihydroxy-acid dehydratase 0.81 26
Pseudomonas stutzeri RCH2 0.34 Psest_3298 histidinol dehydrogenase 0.75 Psest_0234 dihydroxy-acid dehydratase — —
Agrobacterium fabrum C58 0.34 Atu0537 histidinol dehydrogenase 0.73 Atu1918 dihydroxy-acid dehydratase — —
Dinoroseobacter shibae DFL-12 0.34 Dshi_0979 Histidinol dehydrogenase (RefSeq) 0.31 Dshi_0129 dihydroxy-acid dehydratase (RefSeq) — —
Magnetospirillum magneticum AMB-1 0.34 AMB_RS16905 histidinol dehydrogenase 0.73 AMB_RS12770 dihydroxy-acid dehydratase — —
Herbaspirillum seropedicae SmR1 0.33 HSERO_RS20345 histidinol dehydrogenase 0.74 HSERO_RS02650 dihydroxy-acid dehydratase 0.87 13
Pseudomonas fluorescens SBW25-INTG 0.33 PFLU_RS04470 histidinol dehydrogenase 0.75 PFLU_RS28535 dihydroxy-acid dehydratase 0.73 19
Pseudomonas fluorescens FW300-N1B4 0.33 Pf1N1B4_1066 Histidinol dehydrogenase (EC 1.1.1.23) 0.75 Pf1N1B4_2303 Dihydroxy-acid dehydratase (EC 4.2.1.9) — —
Phaeobacter inhibens DSM 17395 0.33 PGA1_c31190 histidinol dehydrogenase HisD 0.70 PGA1_c29490 dihydroxy-acid dehydratase LivD — —
Pseudomonas fluorescens SBW25 0.33 PFLU_RS04470 histidinol dehydrogenase 0.75 PFLU_RS28535 dihydroxy-acid dehydratase 0.74 8
Pseudomonas simiae WCS417 0.33 PS417_04420 histidinol dehydrogenase 0.75 PS417_26890 dihydroxy-acid dehydratase 0.89 16
Variovorax sp. SCN45 0.33 GFF5345 Histidinol dehydrogenase (EC 1.1.1.23) 0.31 GFF471 Dihydroxy-acid dehydratase (EC 4.2.1.9) — —
Variovorax sp. OAS795 0.33 ABID97_RS23160 histidinol dehydrogenase 0.31 ABID97_RS17500 dihydroxy-acid dehydratase — —
Pseudomonas fluorescens FW300-N2C3 0.33 AO356_06965 histidinol dehydrogenase 0.75 AO356_13250 dihydroxy-acid dehydratase 0.90 13
Marinobacter adhaerens HP15 0.33 HP15_2428 histidinol dehydrogenase 0.70 HP15_595 dihydroxy-acid dehydratase low > 73
Pseudomonas syringae pv. syringae B728a ΔmexB 0.33 Psyr_4133 histidinol dehydrogenase 0.74 Psyr_0469 dihydroxyacid dehydratase 0.91 6
Pseudomonas syringae pv. syringae B728a 0.33 Psyr_4133 histidinol dehydrogenase 0.74 Psyr_0469 dihydroxyacid dehydratase 0.92 8
Pseudomonas fluorescens FW300-N2E2 0.33 Pf6N2E2_3252 Histidinol dehydrogenase (EC 1.1.1.23) 0.75 Pf6N2E2_4564 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.78 14
Dechlorosoma suillum PS 0.33 Dsui_1411 histidinol dehydrogenase 0.74 Dsui_1122 dihydroxy-acid dehydratase — —
Pseudomonas fluorescens GW456-L13 0.33 PfGW456L13_5000 Histidinol dehydrogenase (EC 1.1.1.23) 0.75 PfGW456L13_973 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.84 37
Pseudomonas fluorescens FW300-N2E3 0.33 AO353_05110 histidinol dehydrogenase 0.75 AO353_08345 dihydroxy-acid dehydratase 0.91 11
Pseudomonas sp. RS175 0.33 PFR28_00187 Histidinol dehydrogenase 0.75 PFR28_04278 Dihydroxy-acid dehydratase 0.82 3
Synechococcus elongatus PCC 7942 0.33 Synpcc7942_1519 hisD histidinol dehydrogenase 0.75 Synpcc7942_0626 ilvD dihydroxy-acid dehydratase — —
Pseudomonas putida KT2440 0.32 PP_0966 Histidinol dehydrogenase 0.74 PP_5128 Dihydroxy-acid dehydratase 0.93 7
Ralstonia solanacearum PSI07 0.32 RPSI07_RS10390 histidinol dehydrogenase 0.29 RPSI07_RS12840 dihydroxy-acid dehydratase — —
Rhodopseudomonas palustris CGA009 0.32 TX73_023540 histidinol dehydrogenase 0.74 TX73_007515 dihydroxy-acid dehydratase — —
Ralstonia sp. UNC404CL21Col 0.32 ABZR87_RS02500 histidinol dehydrogenase 0.75 ABZR87_RS00240 dihydroxy-acid dehydratase — —
Acinetobacter radioresistens SK82 0.32 MPMX26_02587 Histidinol dehydrogenase 0.29 MPMX26_03019 Dihydroxy-acid dehydratase low > 36
Acidovorax sp. GW101-3H11 0.32 Ac3H11_4724 Histidinol dehydrogenase (EC 1.1.1.23) 0.74 Ac3H11_955 Dihydroxy-acid dehydratase (EC 4.2.1.9) — —
Ralstonia solanacearum IBSBF1503 0.32 RALBFv3_RS06845 histidinol dehydrogenase 0.29 RALBFv3_RS04535 dihydroxy-acid dehydratase — —
Desulfovibrio vulgaris Hildenborough JW710 0.32 DVU0796 hisD histidinol dehydrogenase (TIGR) 0.39 DVU3373 ilvD dihydroxy-acid dehydratase (TIGR) 0.79 28
Ralstonia solanacearum UW163 0.32 UW163_RS06770 histidinol dehydrogenase 0.29 UW163_RS09135 dihydroxy-acid dehydratase — —
Ralstonia solanacearum GMI1000 0.32 RS_RS14790 histidinol dehydrogenase 0.28 RS_RS12105 dihydroxy-acid dehydratase — —
Azospirillum sp. SherDot2 0.32 MPMX19_05543 Histidinol dehydrogenase 0.74 MPMX19_05356 Dihydroxy-acid dehydratase — —
Bosea sp. OAE506 0.32 ABIE41_RS24015 histidinol dehydrogenase 0.29 ABIE41_RS15690 dihydroxy-acid dehydratase — —
Sphingomonas koreensis DSMZ 15582 0.31 Ga0059261_1281 histidinol dehydrogenase 0.28 Ga0059261_4216 Dihydroxyacid dehydratase/phosphogluconate dehydratase 0.97 18
Rhodospirillum rubrum S1H 0.31 Rru_A2771 Histidinol dehydrogenase (NCBI) 0.71 Rru_A1786 Dihydroxy-acid dehydratase (NCBI) low > 58
Paraburkholderia graminis OAS925 0.31 ABIE53_003701 histidinol dehydrogenase 0.74 ABIE53_006513 dihydroxy-acid dehydratase — —
Burkholderia phytofirmans PsJN 0.31 BPHYT_RS17710 histidinol dehydrogenase 0.74 BPHYT_RS10100 dihydroxy-acid dehydratase — —
Paraburkholderia sabiae LMG 24235 0.31 QEN71_RS27865 histidinol dehydrogenase 0.74 QEN71_RS21095 dihydroxy-acid dehydratase low > 153
Hydrogenophaga sp. GW460-11-11-14-LB1 0.31 GFF1314 Histidinol dehydrogenase (EC 1.1.1.23) 0.64 GFF2073 Dihydroxy-acid dehydratase (EC 4.2.1.9) — —
Paraburkholderia bryophila 376MFSha3.1 0.31 H281DRAFT_05652 histidinol dehydrogenase 0.74 H281DRAFT_05312 dihydroxyacid dehydratase — —
Castellaniella sp019104865 MT123 0.31 ABCV34_RS11230 histidinol dehydrogenase 0.72 ABCV34_RS14810 dihydroxy-acid dehydratase low > 48
Desulfovibrio vulgaris Miyazaki F 0.30 DvMF_2814 hisD histidinol dehydrogenase (RefSeq) 0.39 DvMF_2034 dihydroxy-acid dehydratase (RefSeq) 0.84 30
Bifidobacterium breve UCC2003 0.28 BBR_RS17055 histidinol dehydrogenase 0.56 BBR_RS17635 dihydroxy-acid dehydratase 0.31 32
Caulobacter crescentus NA1000 Δfur 0.27 CCNA_02431 histidinol dehydrogenase 0.72 CCNA_03139 dihydroxy-acid dehydratase low > 67
Caulobacter crescentus NA1000 0.27 CCNA_02431 histidinol dehydrogenase 0.72 CCNA_03139 dihydroxy-acid dehydratase 0.98 5
Mycobacterium tuberculosis H37Rv 0.27 Rv1599 Probable histidinol dehydrogenase HisD (HDH) 0.31 Rv0189c Probable dihydroxy-acid dehydratase IlvD (dad) — —

Not shown: 1 genomes with orthologs for b2020 only; 1 genomes with orthologs for b3771 only