Conservation of cofitness between b2025 and b3770 in Escherichia coli BW25113

101 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2025 hisF imidazole glycerol phosphate synthase subunit HisF (NCBI) 1.0 b3770 ilvE branched-chain amino acid aminotransferase (NCBI) 0.97 4
Escherichia coli ECRC102 1.00 NIAGMN_22435 hisF Imidazole glycerol phosphate synthase subunit HisF 1.00 NIAGMN_12400 ilvE branched-chain-amino-acid transaminase
Escherichia coli ECRC101 1.00 OKFHMN_24490 hisF Imidazole glycerol phosphate synthase subunit HisF 1.00 OKFHMN_14645 ilvE branched-chain-amino-acid transaminase
Escherichia coli ECRC101 1.00 MCAODC_20450 hisF Imidazole glycerol phosphate synthase subunit HisF 1.00 MCAODC_05150 ilvE branched-chain-amino-acid transaminase
Escherichia coli ECRC62 1.00 BNILDI_14715 hisF Imidazole glycerol phosphate synthase subunit HisF 1.00 BNILDI_04745 ilvE branched-chain-amino-acid transaminase
Escherichia coli ECRC99 1.00 KEDOAH_03660 hisF Imidazole glycerol phosphate synthase subunit HisF 1.00 KEDOAH_13505 ilvE branched-chain-amino-acid transaminase
Escherichia fergusonii Becca 1.00 EFB2_01831 Imidazole glycerol phosphate synthase subunit HisF 1.00 EFB2_04866 Branched-chain-amino-acid aminotransferase low > 86
Escherichia coli ECRC98 1.00 JDDGAC_28600 hisF Imidazole glycerol phosphate synthase subunit HisF 1.00 JDDGAC_18265 ilvE branched-chain-amino-acid transaminase
Escherichia coli Nissle 1917 1.00 ECOLIN_RS11970 imidazole glycerol phosphate synthase subunit HisF 1.00 ECOLIN_RS21660 branched-chain-amino-acid transaminase low > 52
Escherichia coli ECOR38 0.99 HEPCGN_03195 hisF Imidazole glycerol phosphate synthase subunit HisF 1.00 HEPCGN_13355 ilvE branched-chain-amino-acid transaminase low > 85
Escherichia coli ECOR27 0.99 NOLOHH_15805 hisF Imidazole glycerol phosphate synthase subunit HisF 1.00 NOLOHH_06780 ilvE branched-chain-amino-acid transaminase low > 57
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_01675 Imidazole glycerol phosphate synthase subunit HisF 1.00 OHPLBJKB_04283 Branched-chain-amino-acid aminotransferase low > 73
Escherichia coli BL21 0.99 ECD_01927 imidazole glycerol phosphate synthase, catalytic subunit with HisH 1.00 ECD_03648 branched-chain amino acid aminotransferase
Enterobacter sp. TBS_079 0.97 MPMX20_03007 Imidazole glycerol phosphate synthase subunit HisF 0.99 MPMX20_04500 Branched-chain-amino-acid aminotransferase low > 85
Enterobacter asburiae PDN3 0.96 EX28DRAFT_0534 imidazoleglycerol phosphate synthase, cyclase subunit 0.98 EX28DRAFT_4442 branched-chain amino acid aminotransferase, group I 0.80 31
Klebsiella michiganensis M5al 0.96 BWI76_RS18950 imidazole glycerol phosphate synthase cyclase subunit 0.97 BWI76_RS00970 branched chain amino acid aminotransferase 0.54 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.95 GFF3907 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) 0.98 GFF2902 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 78
Serratia liquefaciens MT49 0.95 IAI46_08185 imidazole glycerol phosphate synthase subunit HisF 0.92 IAI46_24350 branched-chain-amino-acid transaminase low > 86
Erwinia tracheiphila SCR3 0.93 LU632_RS08920 hisF imidazole glycerol phosphate synthase subunit HisF 0.90 LU632_RS24405 branched-chain amino acid transaminase 0.76 38
Dickeya dadantii 3937 0.93 DDA3937_RS09710 imidazole glycerol phosphate synthase subunit HisF 0.91 DDA3937_RS20160 branched-chain-amino-acid transaminase 0.81 42
Dickeya dianthicola ME23 0.92 DZA65_RS10030 imidazole glycerol phosphate synthase subunit HisF 0.91 DZA65_RS21340 branched-chain amino acid transaminase 0.72 43
Dickeya dianthicola 67-19 0.92 HGI48_RS09720 imidazole glycerol phosphate synthase subunit HisF 0.90 HGI48_RS20300 branched-chain-amino-acid transaminase
Pectobacterium carotovorum WPP14 0.91 HER17_RS12255 imidazole glycerol phosphate synthase subunit HisF 0.90 HER17_RS01070 branched-chain amino acid transaminase low > 75
Rahnella sp. WP5 0.91 EX31_RS11465 imidazole glycerol phosphate synthase subunit HisF 0.90 EX31_RS15000 branched-chain amino acid transaminase 0.91 60
Pantoea sp. MT58 0.90 IAI47_07065 imidazole glycerol phosphate synthase subunit HisF 0.91 IAI47_01030 branched-chain amino acid transaminase 0.97 14
Vibrio cholerae E7946 ATCC 55056 0.87 CSW01_05775 imidazole glycerol phosphate synthase cyclase subunit 0.75 CSW01_00145 branched-chain-amino-acid transaminase low > 62
Shewanella amazonensis SB2B 0.77 Sama_1947 imidazole glycerol phosphate synthase subunit HisF (RefSeq) 0.19 Sama_3299 branched-chain amino acid aminotransferase (RefSeq) low > 62
Alteromonas macleodii MIT1002 0.76 MIT1002_02638 Imidazole glycerol phosphate synthase subunit HisF 0.17 MIT1002_00377 Branched-chain-amino-acid aminotransferase 2 0.92 41
Shewanella oneidensis MR-1 0.75 SO2068 hisF hisF protein (cyclase) (NCBI ptt file) 0.19 SO0340 ilvE branched-chain amino acid aminotransferase (NCBI ptt file) 0.87 69
Shewanella sp. ANA-3 0.75 Shewana3_1848 imidazole glycerol phosphate synthase subunit HisF (RefSeq) 0.19 Shewana3_3830 branched-chain amino acid aminotransferase (RefSeq) 0.85 73
Shewanella loihica PV-4 0.75 Shew_2203 imidazole glycerol phosphate synthase subunit HisF (RefSeq) 0.68 Shew_0291 branched-chain amino acid aminotransferase (RefSeq) 0.92 34
Rhodanobacter denitrificans FW104-10B01 0.65 LRK54_RS01580 imidazole glycerol phosphate synthase subunit HisF 0.56 LRK54_RS12020 branched-chain amino acid transaminase low > 59
Lysobacter sp. OAE881 0.65 ABIE51_RS13300 imidazole glycerol phosphate synthase subunit HisF 0.55 ABIE51_RS16505 branched-chain amino acid transaminase low > 62
Rhodanobacter denitrificans MT42 0.64 LRK55_RS01360 imidazole glycerol phosphate synthase subunit HisF 0.56 LRK55_RS11755 branched-chain amino acid transaminase low > 63
Rhodanobacter sp. FW510-T8 0.64 OKGIIK_04975 hisF imidazole glycerol phosphate synthase subunit HisF 0.56 OKGIIK_11840 ilvE branched-chain amino acid transaminase low > 52
Dyella japonica UNC79MFTsu3.2 0.63 ABZR86_RS06705 imidazole glycerol phosphate synthase subunit HisF 0.56 ABZR86_RS15965 branched-chain amino acid transaminase 0.96 2
Xanthomonas campestris pv. campestris strain 8004 0.63 Xcc-8004.2943.1 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) 0.19 Xcc-8004.4199.1 Branched-chain amino acid aminotransferase (EC 2.6.1.42) 0.66 68
Brevundimonas sp. GW460-12-10-14-LB2 0.57 A4249_RS10715 imidazole glycerol phosphate synthase subunit HisF 0.27 A4249_RS09820 branched-chain amino acid aminotransferase
Pontibacter actiniarum KMM 6156, DSM 19842 0.47 CA264_05110 imidazole glycerol phosphate synthase cyclase subunit 0.32 CA264_06940 branched-chain amino acid aminotransferase low > 74
Phocaeicola vulgatus CL09T03C04 0.46 HMPREF1058_RS06175 imidazole glycerol phosphate synthase subunit HisF 0.18 HMPREF1058_RS02220 branched-chain amino acid aminotransferase 0.75 43
Phocaeicola dorei CL03T12C01 0.46 ABI39_RS19930 imidazole glycerol phosphate synthase subunit HisF 0.18 ABI39_RS01415 branched-chain amino acid aminotransferase 0.58 62
Bacteroides thetaiotaomicron VPI-5482 0.44 BT1378 imidazole glycerol phosphate synthase subunit hisF (NCBI ptt file) 0.19 BT3892 branched-chain amino acid aminotransferase (NCBI ptt file)
Bacteroides ovatus ATCC 8483 0.44 BACOVA_00219 imidazoleglycerol phosphate synthase, cyclase subunit 0.30 BACOVA_03679 branched-chain-amino-acid transaminase low > 94
Parabacteroides merdae CL09T00C40 0.43 HMPREF1078_RS13565 imidazole glycerol phosphate synthase subunit HisF 0.19 HMPREF1078_RS07855 branched-chain amino acid aminotransferase low > 61
Mucilaginibacter yixingensis YX-36 DSM 26809 0.43 ABZR88_RS06855 imidazole glycerol phosphate synthase subunit HisF 0.16 ABZR88_RS22095 branched-chain amino acid aminotransferase
Ralstonia solanacearum UW163 0.43 UW163_RS06800 imidazole glycerol phosphate synthase subunit HisF 0.46 UW163_RS01455 branched-chain amino acid transaminase
Ralstonia solanacearum IBSBF1503 0.43 RALBFv3_RS06815 imidazole glycerol phosphate synthase subunit HisF 0.46 RALBFv3_RS12155 branched-chain amino acid transaminase
Ralstonia solanacearum PSI07 0.42 RPSI07_RS10420 imidazole glycerol phosphate synthase subunit HisF 0.45 RPSI07_RS21175 branched-chain amino acid transaminase
Pseudomonas sp. S08-1 0.42 OH686_14595 Imidazole glycerol phosphate synthase cyclase subunit 0.46 OH686_09695 branched-chain amino acid aminotransferase low > 80
Ralstonia solanacearum GMI1000 0.42 RS_RS14760 imidazole glycerol phosphate synthase subunit HisF 0.45 RS_RS02840 branched-chain amino acid transaminase
Ralstonia sp. UNC404CL21Col 0.42 ABZR87_RS02470 imidazole glycerol phosphate synthase subunit HisF 0.25 ABZR87_RS18540 branched-chain amino acid aminotransferase
Bacteroides stercoris CC31F 0.42 HMPREF1181_RS11070 imidazole glycerol phosphate synthase subunit HisF 0.19 HMPREF1181_RS06865 branched-chain amino acid aminotransferase low > 56
Pseudomonas stutzeri RCH2 0.42 Psest_0156 imidazoleglycerol phosphate synthase, cyclase subunit 0.46 Psest_0450 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data)
Cupriavidus basilensis FW507-4G11 0.42 RR42_RS18885 imidazole glycerol phosphate synthase 0.20 RR42_RS25890 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data)
Echinicola vietnamensis KMM 6221, DSM 17526 0.41 Echvi_2516 imidazoleglycerol phosphate synthase, cyclase subunit 0.18 Echvi_2202 branched-chain amino acid aminotransferase, group II low > 79
Burkholderia phytofirmans PsJN 0.41 BPHYT_RS17680 imidazole glycerol phosphate synthase subunit HisF 0.43 BPHYT_RS16285 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) low > 109
Paraburkholderia bryophila 376MFSha3.1 0.41 H281DRAFT_05659 imidazole glycerol phosphate synthase subunit hisF 0.43 H281DRAFT_04193 branched chain amino acid aminotransferase apoenzyme
Caulobacter crescentus NA1000 0.41 CCNA_03853 imidazole glycerol phosphate synthase, cyclase subunit 0.31 CCNA_03024 branched-chain amino acid aminotransferase low > 66
Caulobacter crescentus NA1000 Δfur 0.41 CCNA_03853 imidazole glycerol phosphate synthase, cyclase subunit 0.31 CCNA_03024 branched-chain amino acid aminotransferase low > 67
Pseudomonas putida KT2440 0.41 PP_0293 Imidazole glycerol phosphate synthase subunit HisF 0.19 PP_3511 Branched-chain-amino-acid aminotransferase 0.81 9
Variovorax sp. OAS795 0.41 ABID97_RS23105 imidazole glycerol phosphate synthase subunit HisF 0.44 ABID97_RS03790 branched-chain amino acid transaminase
Paraburkholderia graminis OAS925 0.41 ABIE53_003695 cyclase 0.43 ABIE53_003432 branched-chain amino acid aminotransferase
Paraburkholderia sabiae LMG 24235 0.40 QEN71_RS27835 imidazole glycerol phosphate synthase subunit HisF 0.44 QEN71_RS02410 branched-chain amino acid transaminase low > 153
Pseudomonas syringae pv. syringae B728a ΔmexB 0.40 Psyr_4893 imidazole glycerol phosphate synthase subunit hisF 0.22 Psyr_1148 branched chain amino acid aminotransferase apoenzyme
Pseudomonas syringae pv. syringae B728a 0.40 Psyr_4893 imidazole glycerol phosphate synthase subunit hisF 0.22 Psyr_1148 branched chain amino acid aminotransferase apoenzyme 0.58 48
Bifidobacterium breve UCC2003 0.40 BBR_RS16095 imidazole glycerol phosphate synthase subunit HisF 0.17 BBR_RS15210 branched-chain amino acid aminotransferase low > 34
Azospirillum brasilense Sp245 0.40 AZOBR_RS01685 imidazole glycerol phosphate synthase 0.31 AZOBR_RS16425 branched-chain amino acid aminotransferase low > 97
Pseudomonas fluorescens FW300-N2E3 0.40 AO353_12090 imidazole glycerol phosphate synthase subunit HisF 0.20 AO353_26655 branched-chain amino acid aminotransferase low > 101
Pseudomonas fluorescens SBW25-INTG 0.40 PFLU_RS01625 imidazole glycerol phosphate synthase subunit HisF 0.21 PFLU_RS19375 branched-chain amino acid aminotransferase low > 109
Pseudomonas fluorescens FW300-N1B4 0.40 Pf1N1B4_1623 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) 0.22 Pf1N1B4_4476 Branched-chain amino acid aminotransferase (EC 2.6.1.42)
Pseudomonas fluorescens FW300-N2E2 0.40 Pf6N2E2_3838 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) 0.21 Pf6N2E2_477 Branched-chain amino acid aminotransferase (EC 2.6.1.42)
Pseudomonas fluorescens SBW25 0.40 PFLU_RS01625 imidazole glycerol phosphate synthase subunit HisF 0.21 PFLU_RS19375 branched-chain amino acid aminotransferase low > 109
Azospirillum sp. SherDot2 0.40 MPMX19_02542 Imidazole glycerol phosphate synthase subunit HisF 0.18 MPMX19_02406 Branched-chain-amino-acid aminotransferase
Pseudomonas sp. RS175 0.40 PFR28_04933 Imidazole glycerol phosphate synthase subunit HisF 0.21 PFR28_02449 putative branched-chain-amino-acid aminotransferase low > 88
Pseudomonas fluorescens FW300-N2C3 0.40 AO356_09795 imidazole glycerol phosphate synthase subunit HisF 0.21 AO356_22970 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) low > 104
Acinetobacter radioresistens SK82 0.40 MPMX26_02854 Imidazole glycerol phosphate synthase subunit HisF 0.40 MPMX26_00445 Branched-chain-amino-acid aminotransferase 0.89 21
Pseudomonas simiae WCS417 0.40 PS417_01580 imidazole glycerol phosphate synthase 0.21 PS417_17565 branched-chain amino acid aminotransferase 0.38 83
Pseudomonas fluorescens GW456-L13 0.40 PfGW456L13_358 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) 0.27 PfGW456L13_4923 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 87
Kangiella aquimarina DSM 16071 0.39 B158DRAFT_2291 imidazoleglycerol phosphate synthase, cyclase subunit 0.20 B158DRAFT_0078 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase low > 40
Herbaspirillum seropedicae SmR1 0.39 HSERO_RS20315 imidazole glycerol phosphate synthase 0.44 HSERO_RS03330 branched-chain amino acid aminotransferase low > 78
Variovorax sp. SCN45 0.39 GFF5357 Imidazole glycerol phosphate synthase cyclase subunit 0.44 GFF5079 Branched-chain amino acid aminotransferase (EC 2.6.1.42)
Marinobacter adhaerens HP15 0.39 HP15_3009 protein containing histidine biosynthesis, HisF domain 0.43 HP15_436 branched-chain-amino-acid aminotransferase
Hydrogenophaga sp. GW460-11-11-14-LB1 0.38 GFF1309 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) 0.46 GFF1835 Branched-chain amino acid aminotransferase (EC 2.6.1.42)
Dechlorosoma suillum PS 0.38 Dsui_1418 imidazoleglycerol phosphate synthase, cyclase subunit 0.47 Dsui_2030 branched-chain amino acid aminotransferase, group I
Methanococcus maripaludis JJ 0.38 MMJJ_RS05490 imidazole glycerol phosphate synthase subunit HisF 0.31 MMJJ_RS04725 branched-chain-amino-acid transaminase low > 28
Methanococcus maripaludis S2 0.38 MMP_RS08865 imidazole glycerol phosphate synthase subunit HisF 0.31 MMP_RS00760 branched-chain-amino-acid transaminase
Castellaniella sp019104865 MT123 0.37 ABCV34_RS11250 imidazole glycerol phosphate synthase subunit HisF 0.45 ABCV34_RS07930 branched-chain amino acid transaminase low > 48
Magnetospirillum magneticum AMB-1 0.37 AMB_RS22925 imidazole glycerol phosphate synthase cyclase subunit 0.31 AMB_RS02850 branched-chain amino acid aminotransferase
Mycobacterium tuberculosis H37Rv 0.37 Rv1605 Probable cyclase HisF 0.19 Rv2210c Branched-chain amino acid transaminase IlvE
Dinoroseobacter shibae DFL-12 0.37 Dshi_2576 imidazoleglycerol phosphate synthase, cyclase subunit (RefSeq) 0.26 Dshi_3301 branched-chain amino acid aminotransferase (RefSeq)
Desulfovibrio vulgaris Hildenborough JW710 0.37 DVU0286 hisF imidazoleglycerol phosphate synthase, cyclase subunit (TIGR) 0.46 DVU3197 ilvE branched-chain amino acid aminotransferase (TIGR) 0.87 16
Synechococcus elongatus PCC 7942 0.37 Synpcc7942_2087 hisF imidazole glycerol phosphate synthase subunit HisF 0.29 Synpcc7942_1029 ilvE branched-chain amino acid aminotransferase
Agrobacterium fabrum C58 0.37 Atu0039 imidazoleglycerol-phosphate synthase cyclase 0.18 Atu0871 branched-chain-amino-acid aminotransferase low > 89
Desulfovibrio vulgaris Miyazaki F 0.36 DvMF_2304 imidazole glycerol phosphate synthase subunit HisF (RefSeq) 0.46 DvMF_2268 branched-chain amino acid aminotransferase (RefSeq) low > 51
Sinorhizobium meliloti 1021 0.36 SMc02569 imidazole glycerol phosphate synthase subunit HisF 0.21 SMc02896 branched-chain amino acid aminotransferase low > 103
Rhodospirillum rubrum S1H 0.36 Rru_A3594 Histidine biosynthesis protein HisF (NCBI) 0.32 Rru_A2223 Branched-chain amino acid aminotransferase I (NCBI) low > 58
Rhizobium sp. OAE497 0.36 ABIE40_RS19440 imidazole glycerol phosphate synthase subunit HisF 0.19 ABIE40_RS22240 branched-chain amino acid aminotransferase low > 107
Sphingomonas koreensis DSMZ 15582 0.35 Ga0059261_1048 imidazoleglycerol phosphate synthase, cyclase subunit 0.23 Ga0059261_3811 branched-chain amino acid aminotransferase, group II 0.98 21
Acidovorax sp. GW101-3H11 0.34 Ac3H11_4733 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) 0.46 Ac3H11_3369 Branched-chain amino acid aminotransferase (EC 2.6.1.42)
Bosea sp. OAE506 0.34 ABIE41_RS03810 imidazole glycerol phosphate synthase subunit HisF 0.28 ABIE41_RS11405 branched-chain amino acid aminotransferase
Phaeobacter inhibens DSM 17395 0.34 PGA1_c09240 imidazole glycerol phosphate synthase subunit HisF 0.29 PGA1_c34110 branched-chain-amino-acid aminotransferase IlvE
Rhodopseudomonas palustris CGA009 0.33 TX73_001625 imidazole glycerol phosphate synthase subunit HisF 0.18 TX73_022650 branched-chain amino acid aminotransferase

Not shown: 0 genomes with orthologs for b2025 only; 1 genomes with orthologs for b3770 only