Conservation of cofitness between b2020 and b3770 in Escherichia coli BW25113

101 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2020 hisD histidinol dehydrogenase (NCBI) 1.0 b3770 ilvE branched-chain amino acid aminotransferase (NCBI) 0.97 3
Escherichia coli ECOR27 0.99 NOLOHH_15830 hisD Histidinol dehydrogenase 1.00 NOLOHH_06780 ilvE branched-chain-amino-acid transaminase 0.54 57
Escherichia coli ECRC62 0.99 BNILDI_14740 hisD Histidinol dehydrogenase 1.00 BNILDI_04745 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli BL21 0.99 ECD_01922 bifunctional histidinal dehydrogenase/ histidinol dehydrogenase 1.00 ECD_03648 branched-chain amino acid aminotransferase 0.35 11
Escherichia coli Nissle 1917 0.99 ECOLIN_RS11945 histidinol dehydrogenase 1.00 ECOLIN_RS21660 branched-chain-amino-acid transaminase — —
Escherichia coli ECOR38 0.99 HEPCGN_03220 hisD Histidinol dehydrogenase 1.00 HEPCGN_13355 ilvE branched-chain-amino-acid transaminase low > 85
Escherichia coli HS(pFamp)R (ATCC 700891) 0.98 OHPLBJKB_01680 Histidinol dehydrogenase 1.00 OHPLBJKB_04283 Branched-chain-amino-acid aminotransferase low > 73
Escherichia fergusonii Becca 0.98 EFB2_01836 Histidinol dehydrogenase 1.00 EFB2_04866 Branched-chain-amino-acid aminotransferase low > 86
Escherichia coli ECRC101 0.98 OKFHMN_24515 hisD Histidinol dehydrogenase 1.00 OKFHMN_14645 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC102 0.98 NIAGMN_22460 hisD Histidinol dehydrogenase 1.00 NIAGMN_12400 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC98 0.98 JDDGAC_28625 hisD Histidinol dehydrogenase 1.00 JDDGAC_18265 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC101 0.98 MCAODC_20425 hisD Histidinol dehydrogenase 1.00 MCAODC_05150 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC99 0.98 KEDOAH_03635 hisD Histidinol dehydrogenase 1.00 KEDOAH_13505 ilvE branched-chain-amino-acid transaminase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF3912 Histidinol dehydrogenase (EC 1.1.1.23) 0.98 GFF2902 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 78
Enterobacter asburiae PDN3 0.89 EX28DRAFT_0539 histidinol dehydrogenase 0.98 EX28DRAFT_4442 branched-chain amino acid aminotransferase, group I 0.87 27
Enterobacter sp. TBS_079 0.89 MPMX20_03002 Histidinol dehydrogenase 0.99 MPMX20_04500 Branched-chain-amino-acid aminotransferase low > 85
Klebsiella michiganensis M5al 0.88 BWI76_RS18925 histidinol dehydrogenase 0.97 BWI76_RS00970 branched chain amino acid aminotransferase 0.55 83
Serratia liquefaciens MT49 0.85 IAI46_08210 histidinol dehydrogenase 0.92 IAI46_24350 branched-chain-amino-acid transaminase low > 86
Pantoea sp. MT58 0.82 IAI47_07090 histidinol dehydrogenase 0.91 IAI47_01030 branched-chain amino acid transaminase 0.98 14
Erwinia tracheiphila SCR3 0.81 LU632_RS08945 hisD histidinol dehydrogenase 0.90 LU632_RS24405 branched-chain amino acid transaminase low > 74
Dickeya dadantii 3937 0.80 DDA3937_RS09735 histidinol dehydrogenase 0.91 DDA3937_RS20160 branched-chain-amino-acid transaminase 0.82 49
Pectobacterium carotovorum WPP14 0.80 HER17_RS12230 histidinol dehydrogenase 0.90 HER17_RS01070 branched-chain amino acid transaminase low > 75
Dickeya dianthicola 67-19 0.79 HGI48_RS09745 histidinol dehydrogenase 0.90 HGI48_RS20300 branched-chain-amino-acid transaminase low > 71
Dickeya dianthicola ME23 0.79 DZA65_RS10055 histidinol dehydrogenase 0.91 DZA65_RS21340 branched-chain amino acid transaminase 0.64 57
Rahnella sp. WP5 0.79 EX31_RS11440 histidinol dehydrogenase 0.90 EX31_RS15000 branched-chain amino acid transaminase 0.94 45
Vibrio cholerae E7946 ATCC 55056 0.63 CSW01_05750 histidinol dehydrogenase 0.75 CSW01_00145 branched-chain-amino-acid transaminase low > 62
Shewanella amazonensis SB2B 0.59 Sama_1942 hisD histidinol dehydrogenase (RefSeq) 0.19 Sama_3299 branched-chain amino acid aminotransferase (RefSeq) low > 62
Shewanella loihica PV-4 0.57 Shew_2198 histidinol dehydrogenase (RefSeq) 0.68 Shew_0291 branched-chain amino acid aminotransferase (RefSeq) 0.87 48
Shewanella oneidensis MR-1 0.57 SO2073 hisD histidinol dehydrogenase (NCBI ptt file) 0.19 SO0340 ilvE branched-chain amino acid aminotransferase (NCBI ptt file) 0.86 71
Shewanella sp. ANA-3 0.56 Shewana3_1853 hisD histidinol dehydrogenase (RefSeq) 0.19 Shewana3_3830 branched-chain amino acid aminotransferase (RefSeq) low > 73
Alteromonas macleodii MIT1002 0.54 MIT1002_02633 Histidinol dehydrogenase 0.17 MIT1002_00377 Branched-chain-amino-acid aminotransferase 2 0.95 39
Rhodanobacter denitrificans FW104-10B01 0.53 LRK54_RS01605 histidinol dehydrogenase 0.56 LRK54_RS12020 branched-chain amino acid transaminase low > 59
Rhodanobacter denitrificans MT42 0.53 LRK55_RS01385 histidinol dehydrogenase 0.56 LRK55_RS11755 branched-chain amino acid transaminase low > 63
Dyella japonica UNC79MFTsu3.2 0.53 ABZR86_RS06730 histidinol dehydrogenase 0.56 ABZR86_RS15965 branched-chain amino acid transaminase 0.98 3
Bacteroides ovatus ATCC 8483 0.53 BACOVA_01234 histidinol dehydrogenase 0.30 BACOVA_03679 branched-chain-amino-acid transaminase low > 94
Rhodanobacter sp. FW510-T8 0.53 OKGIIK_04950 hisD histidinol dehydrogenase 0.56 OKGIIK_11840 ilvE branched-chain amino acid transaminase low > 52
Bacteroides thetaiotaomicron VPI-5482 0.52 BT0201 histidinol dehydrogenase (NCBI ptt file) 0.19 BT3892 branched-chain amino acid aminotransferase (NCBI ptt file) — —
Phocaeicola vulgatus CL09T03C04 0.51 HMPREF1058_RS15875 histidinol dehydrogenase 0.18 HMPREF1058_RS02220 branched-chain amino acid aminotransferase 0.69 63
Bacteroides stercoris CC31F 0.50 HMPREF1181_RS04860 histidinol dehydrogenase 0.19 HMPREF1181_RS06865 branched-chain amino acid aminotransferase low > 56
Phocaeicola dorei CL03T12C01 0.50 ABI39_RS11835 histidinol dehydrogenase 0.18 ABI39_RS01415 branched-chain amino acid aminotransferase 0.68 47
Lysobacter sp. OAE881 0.49 ABIE51_RS13325 histidinol dehydrogenase 0.55 ABIE51_RS16505 branched-chain amino acid transaminase low > 62
Parabacteroides merdae CL09T00C40 0.48 HMPREF1078_RS02450 histidinol dehydrogenase 0.19 HMPREF1078_RS07855 branched-chain amino acid aminotransferase low > 61
Xanthomonas campestris pv. campestris strain 8004 0.48 Xcc-8004.2948.1 Histidinol dehydrogenase (EC 1.1.1.23) 0.19 Xcc-8004.4199.1 Branched-chain amino acid aminotransferase (EC 2.6.1.42) 0.69 50
Echinicola vietnamensis KMM 6221, DSM 17526 0.47 Echvi_2459 histidinol dehydrogenase 0.18 Echvi_2202 branched-chain amino acid aminotransferase, group II low > 79
Pontibacter actiniarum KMM 6156, DSM 19842 0.45 CA264_05030 histidinol dehydrogenase 0.32 CA264_06940 branched-chain amino acid aminotransferase low > 74
Pedobacter sp. GW460-11-11-14-LB5 0.44 CA265_RS03635 histidinol dehydrogenase 0.29 CA265_RS15785 branched-chain-amino-acid transaminase low > 88
Mucilaginibacter yixingensis YX-36 DSM 26809 0.44 ABZR88_RS06880 histidinol dehydrogenase 0.16 ABZR88_RS22095 branched-chain amino acid aminotransferase — —
Methanococcus maripaludis JJ 0.38 MMJJ_RS00120 histidinol dehydrogenase 0.31 MMJJ_RS04725 branched-chain-amino-acid transaminase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.38 A4249_RS10695 histidinol dehydrogenase 0.27 A4249_RS09820 branched-chain amino acid aminotransferase — —
Methanococcus maripaludis S2 0.37 MMP_RS05015 histidinol dehydrogenase 0.31 MMP_RS00760 branched-chain-amino-acid transaminase — —
Sinorhizobium meliloti 1021 0.35 SMc02307 histidinol dehydrogenase 0.21 SMc02896 branched-chain amino acid aminotransferase low > 103
Cupriavidus basilensis FW507-4G11 0.35 RR42_RS18915 histidinol dehydrogenase 0.20 RR42_RS25890 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) — —
Rhizobium sp. OAE497 0.34 ABIE40_RS02725 histidinol dehydrogenase 0.19 ABIE40_RS22240 branched-chain amino acid aminotransferase low > 107
Pseudomonas sp. S08-1 0.34 OH686_08470 Histidinol dehydrogenase 0.46 OH686_09695 branched-chain amino acid aminotransferase low > 80
Agrobacterium fabrum C58 0.34 Atu0537 histidinol dehydrogenase 0.18 Atu0871 branched-chain-amino-acid aminotransferase low > 89
Pseudomonas stutzeri RCH2 0.34 Psest_3298 histidinol dehydrogenase 0.46 Psest_0450 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) low > 67
Dinoroseobacter shibae DFL-12 0.34 Dshi_0979 Histidinol dehydrogenase (RefSeq) 0.26 Dshi_3301 branched-chain amino acid aminotransferase (RefSeq) — —
Magnetospirillum magneticum AMB-1 0.34 AMB_RS16905 histidinol dehydrogenase 0.31 AMB_RS02850 branched-chain amino acid aminotransferase — —
Pseudomonas simiae WCS417 0.33 PS417_04420 histidinol dehydrogenase 0.21 PS417_17565 branched-chain amino acid aminotransferase 0.44 78
Pseudomonas fluorescens SBW25 0.33 PFLU_RS04470 histidinol dehydrogenase 0.21 PFLU_RS19375 branched-chain amino acid aminotransferase 0.43 93
Pseudomonas fluorescens SBW25-INTG 0.33 PFLU_RS04470 histidinol dehydrogenase 0.21 PFLU_RS19375 branched-chain amino acid aminotransferase low > 109
Pseudomonas fluorescens FW300-N1B4 0.33 Pf1N1B4_1066 Histidinol dehydrogenase (EC 1.1.1.23) 0.22 Pf1N1B4_4476 Branched-chain amino acid aminotransferase (EC 2.6.1.42) — —
Phaeobacter inhibens DSM 17395 0.33 PGA1_c31190 histidinol dehydrogenase HisD 0.29 PGA1_c34110 branched-chain-amino-acid aminotransferase IlvE — —
Herbaspirillum seropedicae SmR1 0.33 HSERO_RS20345 histidinol dehydrogenase 0.44 HSERO_RS03330 branched-chain amino acid aminotransferase low > 78
Variovorax sp. SCN45 0.33 GFF5345 Histidinol dehydrogenase (EC 1.1.1.23) 0.44 GFF5079 Branched-chain amino acid aminotransferase (EC 2.6.1.42) — —
Variovorax sp. OAS795 0.33 ABID97_RS23160 histidinol dehydrogenase 0.44 ABID97_RS03790 branched-chain amino acid transaminase — —
Pseudomonas fluorescens FW300-N2C3 0.33 AO356_06965 histidinol dehydrogenase 0.21 AO356_22970 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) low > 104
Marinobacter adhaerens HP15 0.33 HP15_2428 histidinol dehydrogenase 0.43 HP15_436 branched-chain-amino-acid aminotransferase — —
Pseudomonas fluorescens FW300-N2E2 0.33 Pf6N2E2_3252 Histidinol dehydrogenase (EC 1.1.1.23) 0.21 Pf6N2E2_477 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 103
Dechlorosoma suillum PS 0.33 Dsui_1411 histidinol dehydrogenase 0.47 Dsui_2030 branched-chain amino acid aminotransferase, group I — —
Pseudomonas syringae pv. syringae B728a 0.33 Psyr_4133 histidinol dehydrogenase 0.22 Psyr_1148 branched chain amino acid aminotransferase apoenzyme 0.62 49
Pseudomonas syringae pv. syringae B728a ΔmexB 0.33 Psyr_4133 histidinol dehydrogenase 0.22 Psyr_1148 branched chain amino acid aminotransferase apoenzyme low > 86
Pseudomonas fluorescens GW456-L13 0.33 PfGW456L13_5000 Histidinol dehydrogenase (EC 1.1.1.23) 0.27 PfGW456L13_4923 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 87
Pseudomonas fluorescens FW300-N2E3 0.33 AO353_05110 histidinol dehydrogenase 0.20 AO353_26655 branched-chain amino acid aminotransferase low > 101
Pseudomonas sp. RS175 0.33 PFR28_00187 Histidinol dehydrogenase 0.21 PFR28_02449 putative branched-chain-amino-acid aminotransferase low > 88
Synechococcus elongatus PCC 7942 0.33 Synpcc7942_1519 hisD histidinol dehydrogenase 0.29 Synpcc7942_1029 ilvE branched-chain amino acid aminotransferase — —
Pseudomonas putida KT2440 0.32 PP_0966 Histidinol dehydrogenase 0.19 PP_3511 Branched-chain-amino-acid aminotransferase 0.92 8
Ralstonia solanacearum PSI07 0.32 RPSI07_RS10390 histidinol dehydrogenase 0.45 RPSI07_RS21175 branched-chain amino acid transaminase — —
Rhodopseudomonas palustris CGA009 0.32 TX73_023540 histidinol dehydrogenase 0.18 TX73_022650 branched-chain amino acid aminotransferase — —
Acinetobacter radioresistens SK82 0.32 MPMX26_02587 Histidinol dehydrogenase 0.40 MPMX26_00445 Branched-chain-amino-acid aminotransferase 0.91 19
Ralstonia sp. UNC404CL21Col 0.32 ABZR87_RS02500 histidinol dehydrogenase 0.25 ABZR87_RS18540 branched-chain amino acid aminotransferase — —
Acidovorax sp. GW101-3H11 0.32 Ac3H11_4724 Histidinol dehydrogenase (EC 1.1.1.23) 0.46 Ac3H11_3369 Branched-chain amino acid aminotransferase (EC 2.6.1.42) — —
Ralstonia solanacearum IBSBF1503 0.32 RALBFv3_RS06845 histidinol dehydrogenase 0.46 RALBFv3_RS12155 branched-chain amino acid transaminase — —
Ralstonia solanacearum UW163 0.32 UW163_RS06770 histidinol dehydrogenase 0.46 UW163_RS01455 branched-chain amino acid transaminase — —
Desulfovibrio vulgaris Hildenborough JW710 0.32 DVU0796 hisD histidinol dehydrogenase (TIGR) 0.46 DVU3197 ilvE branched-chain amino acid aminotransferase (TIGR) 0.83 19
Ralstonia solanacearum GMI1000 0.32 RS_RS14790 histidinol dehydrogenase 0.45 RS_RS02840 branched-chain amino acid transaminase — —
Azospirillum sp. SherDot2 0.32 MPMX19_05543 Histidinol dehydrogenase 0.18 MPMX19_02406 Branched-chain-amino-acid aminotransferase — —
Bosea sp. OAE506 0.32 ABIE41_RS24015 histidinol dehydrogenase 0.28 ABIE41_RS11405 branched-chain amino acid aminotransferase low > 77
Sphingomonas koreensis DSMZ 15582 0.31 Ga0059261_1281 histidinol dehydrogenase 0.23 Ga0059261_3811 branched-chain amino acid aminotransferase, group II 0.97 21
Rhodospirillum rubrum S1H 0.31 Rru_A2771 Histidinol dehydrogenase (NCBI) 0.32 Rru_A2223 Branched-chain amino acid aminotransferase I (NCBI) low > 58
Burkholderia phytofirmans PsJN 0.31 BPHYT_RS17710 histidinol dehydrogenase 0.43 BPHYT_RS16285 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) — —
Paraburkholderia graminis OAS925 0.31 ABIE53_003701 histidinol dehydrogenase 0.43 ABIE53_003432 branched-chain amino acid aminotransferase — —
Paraburkholderia sabiae LMG 24235 0.31 QEN71_RS27865 histidinol dehydrogenase 0.44 QEN71_RS02410 branched-chain amino acid transaminase low > 153
Hydrogenophaga sp. GW460-11-11-14-LB1 0.31 GFF1314 Histidinol dehydrogenase (EC 1.1.1.23) 0.46 GFF1835 Branched-chain amino acid aminotransferase (EC 2.6.1.42) — —
Paraburkholderia bryophila 376MFSha3.1 0.31 H281DRAFT_05652 histidinol dehydrogenase 0.43 H281DRAFT_04193 branched chain amino acid aminotransferase apoenzyme — —
Castellaniella sp019104865 MT123 0.31 ABCV34_RS11230 histidinol dehydrogenase 0.45 ABCV34_RS07930 branched-chain amino acid transaminase low > 48
Desulfovibrio vulgaris Miyazaki F 0.30 DvMF_2814 hisD histidinol dehydrogenase (RefSeq) 0.46 DvMF_2268 branched-chain amino acid aminotransferase (RefSeq) low > 51
Bifidobacterium breve UCC2003 0.28 BBR_RS17055 histidinol dehydrogenase 0.17 BBR_RS15210 branched-chain amino acid aminotransferase low > 34
Caulobacter crescentus NA1000 Δfur 0.27 CCNA_02431 histidinol dehydrogenase 0.31 CCNA_03024 branched-chain amino acid aminotransferase low > 67
Caulobacter crescentus NA1000 0.27 CCNA_02431 histidinol dehydrogenase 0.31 CCNA_03024 branched-chain amino acid aminotransferase low > 66
Mycobacterium tuberculosis H37Rv 0.27 Rv1599 Probable histidinol dehydrogenase HisD (HDH) 0.19 Rv2210c Branched-chain amino acid transaminase IlvE — —
Kangiella aquimarina DSM 16071 0.25 B158DRAFT_2293 histidinol dehydrogenase 0.20 B158DRAFT_0078 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase low > 40

Not shown: 0 genomes with orthologs for b2020 only; 1 genomes with orthologs for b3770 only