| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Azospirillum sp. SherDot2 | 1.0 | MPMX19_00607 | | 3-isopropylmalate dehydrogenase | 1.0 | MPMX19_00635 | | 5,10-methylenetetrahydrofolate reductase | 0.95 | 2 |
| Azospirillum brasilense Sp245 | 0.91 | AZOBR_RS14130 | | 3-isopropylmalate dehydrogenase | 0.90 | AZOBR_RS09540 | | 5 10-methylenetetrahydrofolate reductase | 0.71 | 28 |
| Magnetospirillum magneticum AMB-1 | 0.68 | AMB_RS20570 | | 3-isopropylmalate dehydrogenase | 0.65 | AMB_RS02230 | | methylenetetrahydrofolate reductase | — | — |
| Rhodospirillum rubrum S1H | 0.65 | Rru_A1191 | | 3-isopropylmalate dehydrogenase (NCBI) | 0.62 | Rru_A1530 | | 5,10-methylenetetrahydrofolate reductase (NCBI) | 0.89 | 14 |
| Dinoroseobacter shibae DFL-12 | 0.65 | Dshi_0081 | | 3-isopropylmalate dehydrogenase (RefSeq) | 0.41 | Dshi_2080 | | 5,10-methylenetetrahydrofolate reductase (RefSeq) | — | — |
| Agrobacterium fabrum C58 | 0.65 | Atu2791 | | 3-isopropylmalate dehydrogenase | 0.48 | Atu2123 | | methylenetetrahydrofolate reductase | 0.59 | 81 |
| Sinorhizobium meliloti 1021 | 0.64 | SMc04405 | | 3-isopropylmalate dehydrogenase | 0.50 | SMc01843 | | 5,10-methylenetetrahydrofolate reductase | 0.98 | 5 |
| Rhizobium sp. OAE497 | 0.63 | ABIE40_RS19050 | | 3-isopropylmalate dehydrogenase | 0.52 | ABIE40_RS11950 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.98 | 4 |
| Phaeobacter inhibens DSM 17395 | 0.62 | PGA1_c29830 | | 3-isopropylmalate dehydrogenase LeuB | 0.44 | PGA1_c11700 | | 5,10-methylenetetrahydrofolate reductase MetF | 0.91 | 8 |
| Bosea sp. OAE506 | 0.61 | ABIE41_RS11860 | | 3-isopropylmalate dehydrogenase | 0.63 | ABIE41_RS12475 | | methylenetetrahydrofolate reductase [NAD(P)H] | — | — |
| Rhodopseudomonas palustris CGA009 | 0.61 | TX73_001175 | | 3-isopropylmalate dehydrogenase | 0.57 | TX73_019175 | | methylenetetrahydrofolate reductase [NAD(P)H] | — | — |
| Xanthobacter sp. DMC5 | 0.60 | GFF1695 | | 3-isopropylmalate dehydrogenase | 0.64 | GFF4147 | | 5,10-methylenetetrahydrofolate reductase | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.57 | Pf1N1B4_12 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | 0.38 | Pf1N1B4_2384 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.84 | 20 |
| Pseudomonas fluorescens FW300-N2E3 | 0.57 | AO353_20635 | | 3-isopropylmalate dehydrogenase | 0.37 | AO353_08015 | | 5,10-methylenetetrahydrofolate reductase | 0.86 | 29 |
| Pseudomonas lactucae CFBP13502 | 0.57 | GEMAOFIL_03945 | | 3-isopropylmalate dehydrogenase | 0.38 | GEMAOFIL_05433 | | 5,10-methylenetetrahydrofolate reductase | low | > 93 |
| Pseudomonas fluorescens FW300-N2E2 | 0.57 | Pf6N2E2_66 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | 0.37 | Pf6N2E2_4638 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.72 | 36 |
| Pseudomonas fluorescens FW300-N2C3 | 0.57 | AO356_21415 | | 3-isopropylmalate dehydrogenase | 0.37 | AO356_13605 | | 5,10-methylenetetrahydrofolate reductase | 0.95 | 11 |
| Pseudomonas simiae WCS417 | 0.57 | PS417_18585 | | 3-isopropylmalate dehydrogenase | 0.37 | PS417_26510 | | 5,10-methylenetetrahydrofolate reductase | 0.42 | 81 |
| Pseudomonas fluorescens SBW25 | 0.56 | PFLU_RS20565 | | 3-isopropylmalate dehydrogenase | 0.38 | PFLU_RS28165 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.68 | 14 |
| Pseudomonas fluorescens SBW25-INTG | 0.56 | PFLU_RS20565 | | 3-isopropylmalate dehydrogenase | 0.38 | PFLU_RS28165 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.78 | 20 |
| Pseudomonas segetis P6 | 0.56 | MPMX49_03071 | | 3-isopropylmalate dehydrogenase | 0.37 | MPMX49_00645 | | 5,10-methylenetetrahydrofolate reductase | 0.58 | 49 |
| Pseudomonas sp. RS175 | 0.56 | PFR28_02821 | | 3-isopropylmalate dehydrogenase | 0.37 | PFR28_04202 | | 5,10-methylenetetrahydrofolate reductase | 0.77 | 6 |
| Pseudomonas sp. DMC3 | 0.56 | GFF788 | | 3-isopropylmalate dehydrogenase | 0.38 | GFF171 | | 5,10-methylenetetrahydrofolate reductase | 0.97 | 24 |
| Acinetobacter radioresistens SK82 | 0.56 | MPMX26_00348 | | 3-isopropylmalate dehydrogenase | 0.32 | MPMX26_01002 | | 5,10-methylenetetrahydrofolate reductase | low | > 36 |
| Acinetobacter baumannii LAC-4 | 0.56 | RR41_RS16885 | | 3-isopropylmalate dehydrogenase | 0.33 | RR41_RS05725 | | methylenetetrahydrofolate reductase [NAD(P)H] | low | > 55 |
| Pseudomonas sp. SVBP6 | 0.56 | COO64_RS05650 | leuB | 3-isopropylmalate dehydrogenase | 0.37 | COO64_RS17485 | metF | methylenetetrahydrofolate reductase [NAD(P)H] | 0.98 | 25 |
| Pseudomonas putida KT2440 | 0.55 | PP_1988 | | 3-isopropylmalate dehydrogenase | 0.37 | PP_4977 | | 5,10-methylenetetrahydrofolate reductase | 0.45 | 68 |
| Pseudomonas syringae pv. syringae B728a | 0.55 | Psyr_1985 | | 3-isopropylmalate dehydrogenase | 0.37 | Psyr_0459 | | 5,10-methylenetetrahydrofolate reductase | 0.64 | 56 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.55 | Psyr_1985 | | 3-isopropylmalate dehydrogenase | 0.37 | Psyr_0459 | | 5,10-methylenetetrahydrofolate reductase | low | > 86 |
| Pseudomonas fluorescens GW456-L13 | 0.55 | PfGW456L13_3945 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | 0.38 | PfGW456L13_1050 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.94 | 13 |
| Pseudomonas sp. BP01 | 0.55 | JOY50_RS16615 | leuB | 3-isopropylmalate dehydrogenase | 0.37 | JOY50_RS09810 | metF | methylenetetrahydrofolate reductase [NAD(P)H] | 0.96 | 15 |
| Pseudomonas aeruginosa PA14 | 0.55 | IKLFDK_15865 | | 3-isopropylmalate dehydrogenase | 0.38 | IKLFDK_23270 | | methylenetetrahydrofolate reductase [NAD(P)H] | low | > 100 |
| Pseudomonas sp. S08-1 | 0.55 | OH686_04470 | | 3-isopropylmalate dehydrogenase | 0.37 | OH686_10820 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.79 | 23 |
| Caulobacter crescentus NA1000 Δfur | 0.54 | CCNA_00193 | | 3-isopropylmalate dehydrogenase | 0.57 | CCNA_02224 | | methylenetetrahydrofolate reductase | low | > 67 |
| Caulobacter crescentus NA1000 | 0.54 | CCNA_00193 | | 3-isopropylmalate dehydrogenase | 0.57 | CCNA_02224 | | methylenetetrahydrofolate reductase | 0.96 | 13 |
| Marinobacter adhaerens HP15 | 0.54 | HP15_1832 | | 3-isopropylmalate dehydrogenase | 0.39 | HP15_2917 | | 5,10-methylenetetrahydrofolate reductase-like protein | 0.96 | 2 |
| Pseudomonas stutzeri RCH2 | 0.54 | Psest_2589 | | 3-isopropylmalate dehydrogenase | 0.39 | Psest_0313 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.89 | 16 |
| Kangiella aquimarina DSM 16071 | 0.54 | B158DRAFT_1322 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | 0.54 | B158DRAFT_2461 | | 5,10-methylenetetrahydrofolate reductase (NAD(P)) (EC 1.5.1.20) | low | > 40 |
| Dechlorosoma suillum PS | 0.53 | Dsui_3198 | | 3-isopropylmalate dehydrogenase | 0.37 | Dsui_0640 | | 5,10-methylenetetrahydrofolate reductase | — | — |
| Xanthomonas campestris pv. campestris strain 8004 | 0.52 | Xcc-8004.1053.1 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | 0.36 | Xcc-8004.4336.1 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | low | > 74 |
| Methylophilus sp. DMC18 | 0.51 | GFF648 | | 3-isopropylmalate dehydrogenase | 0.36 | GFF1492 | | 5,10-methylenetetrahydrofolate reductase | — | — |
| Desulfovibrio vulgaris Miyazaki F | 0.51 | DvMF_1794 | | 3-isopropylmalate dehydrogenase (RefSeq) | 0.30 | DvMF_3034 | | 5,10-methylenetetrahydrofolate reductase (RefSeq) | — | — |
| Castellaniella sp019104865 MT123 | 0.50 | ABCV34_RS04280 | | 3-isopropylmalate dehydrogenase | 0.35 | ABCV34_RS13550 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.86 | 23 |
| Herbaspirillum seropedicae SmR1 | 0.50 | HSERO_RS16500 | | 3-isopropylmalate dehydrogenase | 0.33 | HSERO_RS21425 | | 5,10-methylenetetrahydrofolate reductase | low | > 78 |
| Variovorax sp. OAS795 | 0.49 | ABID97_RS08455 | | 3-isopropylmalate dehydrogenase | 0.32 | ABID97_RS25015 | | methylenetetrahydrofolate reductase [NAD(P)H] | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.49 | RR42_RS14385 | | 3-isopropylmalate dehydrogenase | 0.39 | RR42_RS01385 | | 5,10-methylenetetrahydrofolate reductase | 0.77 | 18 |
| Paraburkholderia graminis OAS925 | 0.49 | ABIE53_004804 | | 3-isopropylmalate dehydrogenase | 0.37 | ABIE53_000061 | | methylenetetrahydrofolate reductase (NADPH) | 0.92 | 7 |
| Acidovorax sp. GW101-3H11 | 0.49 | Ac3H11_1528 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | 0.36 | Ac3H11_3045 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.89 | 18 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.49 | H281DRAFT_06072 | | 3-isopropylmalate dehydrogenase | 0.38 | H281DRAFT_05801 | | 5,10-methylenetetrahydrofolate reductase (NAD(P)) | 0.66 | 16 |
| Burkholderia phytofirmans PsJN | 0.49 | BPHYT_RS33900 | | 3-isopropylmalate dehydrogenase | 0.37 | BPHYT_RS18705 | | 5,10-methylenetetrahydrofolate reductase | 0.56 | 88 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.48 | GFF3360 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | 0.33 | GFF1692 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | — | — |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.48 | DVU2985 | leuB | 3-isopropylmalate dehydrogenase (TIGR) | 0.29 | DVU0997 | metF | 5,10-methylenetetrahydrofolate reductase (TIGR) | 0.88 | 20 |
| Ralstonia sp. UNC404CL21Col | 0.48 | ABZR87_RS14530 | | 3-isopropylmalate dehydrogenase | 0.38 | ABZR87_RS04865 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.82 | 28 |
| Paraburkholderia sabiae LMG 24235 | 0.48 | QEN71_RS17620 | | 3-isopropylmalate dehydrogenase | 0.38 | QEN71_RS28715 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.84 | 3 |
| Ralstonia solanacearum GMI1000 | 0.48 | RS_RS09990 | | 3-isopropylmalate dehydrogenase | 0.38 | RS_RS00460 | | methylenetetrahydrofolate reductase [NAD(P)H] | low | > 80 |
| Variovorax sp. SCN45 | 0.48 | GFF3888 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | 0.32 | GFF2055 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | low | > 127 |
| Ralstonia solanacearum UW163 | 0.48 | UW163_RS11115 | | 3-isopropylmalate dehydrogenase | 0.38 | UW163_RS03705 | | methylenetetrahydrofolate reductase [NAD(P)H] | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.48 | RALBFv3_RS02610 | | 3-isopropylmalate dehydrogenase | 0.38 | RALBFv3_RS09875 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.58 | 15 |
| Ralstonia solanacearum PSI07 | 0.47 | RPSI07_RS14705 | | 3-isopropylmalate dehydrogenase | 0.38 | RPSI07_RS23495 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.63 | 22 |
| Klebsiella pneumoniae MKP103 | 0.47 | KDGMDA_12905 | | 3-isopropylmalate dehydrogenase | 0.54 | KDGMDA_09325 | | methylenetetrahydrofolate reductase | low | > 95 |
| Escherichia fergusonii Becca | 0.46 | EFB2_03972 | | 3-isopropylmalate dehydrogenase | 0.54 | EFB2_04672 | | 5,10-methylenetetrahydrofolate reductase | low | > 86 |
| Escherichia coli ECOR38 | 0.46 | HEPCGN_08700 | leuB | 3-isopropylmalate dehydrogenase | 0.55 | HEPCGN_12310 | metF | methylenetetrahydrofolate reductase | 0.92 | 39 |
| Escherichia coli Nissle 1917 | 0.46 | ECOLIN_RS00395 | | 3-isopropylmalate dehydrogenase | 0.54 | ECOLIN_RS22760 | | methylenetetrahydrofolate reductase | 0.94 | 9 |
| Escherichia coli BL21 | 0.46 | ECD_00075 | | 3-isopropylmalate dehydrogenase, NAD(+)-dependent | 0.55 | ECD_03827 | | 5,10-methylenetetrahydrofolate reductase | 0.97 | 7 |
| Escherichia coli ECRC98 | 0.46 | JDDGAC_14315 | leuB | 3-isopropylmalate dehydrogenase | 0.55 | JDDGAC_17290 | metF | methylenetetrahydrofolate reductase | 0.97 | 9 |
| Escherichia coli ECRC100 | 0.46 | OKFHMN_10720 | leuB | 3-isopropylmalate dehydrogenase | 0.55 | OKFHMN_13665 | metF | methylenetetrahydrofolate reductase | 0.99 | 5 |
| Escherichia coli ECRC102 | 0.46 | NIAGMN_08570 | leuB | 3-isopropylmalate dehydrogenase | 0.55 | NIAGMN_11420 | metF | methylenetetrahydrofolate reductase | 0.98 | 15 |
| Escherichia coli ECRC62 | 0.46 | BNILDI_08545 | leuA | 2-isopropylmalate synthase | 0.55 | BNILDI_05725 | metF | methylenetetrahydrofolate reductase | 0.98 | 11 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.46 | OHPLBJKB_03584 | | 3-isopropylmalate dehydrogenase | 0.55 | OHPLBJKB_04109 | | 5,10-methylenetetrahydrofolate reductase | low | > 74 |
| Escherichia coli ECRC99 | 0.46 | KEDOAH_17435 | leuB | 3-isopropylmalate dehydrogenase | 0.55 | KEDOAH_14495 | metF | methylenetetrahydrofolate reductase | — | — |
| Escherichia coli ECOR27 | 0.46 | NOLOHH_03065 | leuA | 2-isopropylmalate synthase | 0.55 | NOLOHH_05810 | metF | methylenetetrahydrofolate reductase | 0.98 | 7 |
| Escherichia coli ECRC101 | 0.46 | MCAODC_01235 | leuB | 3-isopropylmalate dehydrogenase | 0.55 | MCAODC_04165 | metF | methylenetetrahydrofolate reductase | 0.96 | 8 |
| Escherichia coli BW25113 | 0.46 | b0073 | leuB | 3-isopropylmalate dehydrogenase (VIMSS) | 0.55 | b3941 | metF | 5,10-methylenetetrahydrofolate reductase (NCBI) | 0.96 | 9 |
| Vibrio cholerae E7946 ATCC 55056 | 0.46 | CSW01_12600 | | 3-isopropylmalate dehydrogenase | 0.53 | CSW01_13560 | | methylenetetrahydrofolate reductase | low | > 62 |
| Serratia liquefaciens MT49 | 0.46 | IAI46_03350 | | 3-isopropylmalate dehydrogenase | 0.53 | IAI46_24530 | | methylenetetrahydrofolate reductase | 0.72 | 9 |
| Sphingomonas koreensis DSMZ 15582 | 0.46 | Ga0059261_3190 | | 3-isopropylmalate dehydrogenase | 0.59 | Ga0059261_0992 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | low | > 68 |
| Rahnella sp. WP5 | 0.45 | EX31_RS03685 | | 3-isopropylmalate dehydrogenase | 0.54 | EX31_RS14205 | | methylenetetrahydrofolate reductase | 0.92 | 60 |
| Klebsiella michiganensis M5al | 0.45 | BWI76_RS04675 | | 3-isopropylmalate dehydrogenase | 0.55 | BWI76_RS00805 | | 5,10-methylenetetrahydrofolate reductase | 0.89 | 23 |
| Enterobacter asburiae PDN3 | 0.45 | EX28DRAFT_3669 | | 3-isopropylmalate dehydrogenase | 0.56 | EX28DRAFT_4413 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | low | > 76 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.45 | GFF165 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | 0.55 | GFF2329 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | low | > 78 |
| Enterobacter sp. TBS_079 | 0.45 | MPMX20_00768 | | 3-isopropylmalate dehydrogenase | 0.56 | MPMX20_04529 | | 5,10-methylenetetrahydrofolate reductase | 0.75 | 60 |
| Erwinia amylovora T8 | 0.45 | OLJFJH_01290 | | 3-isopropylmalate dehydrogenase | 0.54 | OLJFJH_06105 | | methylenetetrahydrofolate reductase | 0.89 | 32 |
| Pectobacterium carotovorum WPP14 | 0.45 | HER17_RS03080 | | 3-isopropylmalate dehydrogenase | 0.53 | HER17_RS00950 | | methylenetetrahydrofolate reductase | low | > 75 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.44 | ABZR88_RS11605 | | 3-isopropylmalate dehydrogenase | 0.22 | ABZR88_RS20935 | | methylenetetrahydrofolate reductase [NAD(P)H] | — | — |
| Dickeya dianthicola 67-19 | 0.44 | HGI48_RS18060 | | 3-isopropylmalate dehydrogenase | 0.54 | HGI48_RS20415 | | methylenetetrahydrofolate reductase | low | > 71 |
| Pantoea agglomerans CFBP13505 P0401 | 0.44 | PagCFBP13505_RS12995 | | 3-isopropylmalate dehydrogenase | 0.54 | PagCFBP13505_RS18450 | | methylenetetrahydrofolate reductase | low | > 74 |
| Dickeya dianthicola ME23 | 0.43 | DZA65_RS19205 | | 3-isopropylmalate dehydrogenase | 0.54 | DZA65_RS21460 | | methylenetetrahydrofolate reductase | 0.76 | 26 |
| Dickeya dadantii 3937 | 0.43 | DDA3937_RS18120 | | 3-isopropylmalate dehydrogenase | 0.54 | DDA3937_RS00960 | | methylenetetrahydrofolate reductase | low | > 74 |
| Pantoea sp. MT58 | 0.43 | IAI47_16005 | | 3-isopropylmalate dehydrogenase | 0.54 | IAI47_00890 | | methylenetetrahydrofolate reductase | low | > 76 |
| Sphingobium sp. HT1-2 | 0.43 | GFF3458 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | 0.59 | GFF217 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.76 | 41 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.43 | A4249_RS09995 | | 3-isopropylmalate dehydrogenase | 0.54 | A4249_RS07925 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.99 | 19 |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.43 | CA265_RS15850 | | 3-isopropylmalate dehydrogenase | 0.24 | CA265_RS23445 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.94 | 13 |
| Lysobacter sp. OAE881 | 0.43 | ABIE51_RS17585 | | 3-isopropylmalate dehydrogenase | 0.35 | ABIE51_RS16490 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.98 | 5 |
| Erwinia tracheiphila HP pepo 2.2 | 0.42 | IJEDHG_06000 | leuB | 3-isopropylmalate dehydrogenase | 0.52 | IJEDHG_13030 | metF | methylenetetrahydrofolate reductase | low | > 61 |
| Erwinia tracheiphila SCR3 | 0.42 | LU632_RS02875 | leuB | 3-isopropylmalate dehydrogenase | 0.52 | LU632_RS19630 | metF | methylenetetrahydrofolate reductase | low | > 74 |
| Rhodanobacter sp000427505 FW510-R12 | 0.41 | LRK53_RS03100 | | 3-isopropylmalate dehydrogenase | 0.37 | LRK53_RS16505 | | methylenetetrahydrofolate reductase [NAD(P)H] | low | > 59 |
| Alteromonas macleodii MIT1002 | 0.41 | MIT1002_00948 | | 3-isopropylmalate dehydrogenase | 0.56 | MIT1002_03670 | | 5,10-methylenetetrahydrofolate reductase | low | > 70 |
| Shewanella oneidensis MR-1 | 0.41 | SO4235 | leuB | 3-isopropylmalate dehydrogenase (NCBI ptt file) | 0.54 | SO4054 | metF | 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) | 0.98 | 12 |
| Shewanella sp. ANA-3 | 0.41 | Shewana3_3760 | | 3-isopropylmalate dehydrogenase (RefSeq) | 0.54 | Shewana3_3612 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.97 | 4 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.40 | Echvi_2062 | | 3-isopropylmalate dehydrogenase | 0.24 | Echvi_3637 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | — | — |
| Rhodanobacter sp. FW510-T8 | 0.40 | OKGIIK_13595 | leuB | 3-isopropylmalate dehydrogenase | 0.38 | OKGIIK_11830 | metF | methylenetetrahydrofolate reductase [NAD(P)H] | low | > 53 |
| Shewanella amazonensis SB2B | 0.40 | Sama_0336 | | 3-isopropylmalate dehydrogenase (RefSeq) | 0.54 | Sama_3169 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.98 | 6 |
| Cellulophaga baltica 18 | 0.40 | M666_RS15045 | | 3-isopropylmalate dehydrogenase | 0.22 | M666_RS08215 | | methylenetetrahydrofolate reductase [NAD(P)H] | low | > 67 |
| Rhodanobacter denitrificans MT42 | 0.39 | LRK55_RS09965 | | 3-isopropylmalate dehydrogenase | 0.37 | LRK55_RS11765 | | methylenetetrahydrofolate reductase [NAD(P)H] | low | > 63 |
| Shewanella loihica PV-4 | 0.39 | Shew_3471 | | 3-isopropylmalate dehydrogenase (RefSeq) | 0.55 | Shew_0522 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.99 | 7 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.39 | CA264_09445 | | 3-isopropylmalate dehydrogenase | 0.23 | CA264_16780 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.31 | 64 |
| Rhodanobacter denitrificans FW104-10B01 | 0.39 | LRK54_RS10325 | | 3-isopropylmalate dehydrogenase | 0.37 | LRK54_RS12030 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.71 | 36 |
| Dyella japonica UNC79MFTsu3.2 | 0.38 | ABZR86_RS15950 | | 3-isopropylmalate dehydrogenase | 0.39 | ABZR86_RS11570 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.96 | 10 |
| Phocaeicola vulgatus CL09T03C04 | 0.36 | HMPREF1058_RS14565 | | 3-isopropylmalate dehydrogenase | 0.22 | HMPREF1058_RS01490 | | methylenetetrahydrofolate reductase [NAD(P)H] | low | > 67 |
| Parabacteroides merdae CL09T00C40 | 0.36 | HMPREF1078_RS16640 | | 3-isopropylmalate dehydrogenase | 0.22 | HMPREF1078_RS07860 | | methylenetetrahydrofolate reductase [NAD(P)H] | low | > 61 |
| Phocaeicola dorei CL03T12C01 | 0.36 | ABI39_RS10215 | | 3-isopropylmalate dehydrogenase | 0.22 | ABI39_RS15570 | | methylenetetrahydrofolate reductase [NAD(P)H] | low | > 72 |
| Bacteroides stercoris CC31F | 0.35 | HMPREF1181_RS14125 | | 3-isopropylmalate dehydrogenase | 0.21 | HMPREF1181_RS00120 | | methylenetetrahydrofolate reductase [NAD(P)H] | low | > 56 |
| Bacteroides ovatus ATCC 8483 | 0.35 | BACOVA_04600 | | 3-isopropylmalate dehydrogenase | 0.19 | BACOVA_03666 | | methylenetetrahydrofolate reductase (NAD(P)H) | low | > 96 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.35 | BT1857 | | 3-isopropylmalate dehydrogenase (NCBI ptt file) | 0.23 | BT3821 | | 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) | low | > 81 |
Not shown: 2 genomes with orthologs for MPMX19_00607 only; 2 genomes with orthologs for MPMX19_00635 only