Conservation of cofitness between PGA1_c24870 and PGA1_c10810 in Phaeobacter inhibens DSM 17395

97 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Phaeobacter inhibens DSM 17395 1.0 PGA1_c24870 phosphoribosylaminoimidazole carboxylase ATPase subunit PurK 1.0 PGA1_c10810 amidophosphoribosyltransferase PurF 0.93 1
Dinoroseobacter shibae DFL-12 0.71 Dshi_0680 phosphoribosylaminoimidazole carboxylase, ATPase subunit (RefSeq) 0.85 Dshi_2132 amidophosphoribosyltransferase (RefSeq) 0.90 1
Caulobacter crescentus NA1000 0.51 CCNA_03392 phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit 0.54 CCNA_01730 amidophosphoribosyltransferase 0.86 15
Caulobacter crescentus NA1000 Δfur 0.51 CCNA_03392 phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit 0.54 CCNA_01730 amidophosphoribosyltransferase low > 67
Sinorhizobium meliloti 1021 0.50 SMc04002 phosphoribosylaminoimidazole carboxylase ATPase subunit 0.51 SMc00554 amidophosphoribosyltransferase 0.97 1
Agrobacterium fabrum C58 0.49 Atu3755 phosphoribosylaminoimidazole carboxylase ATPase subunit 0.52 Atu1075 amidophosphoribosyltransferase 0.94 1
Rhizobium sp. OAE497 0.49 ABIE40_RS16070 5-(carboxyamino)imidazole ribonucleotide synthase 0.52 ABIE40_RS06270 amidophosphoribosyltransferase 0.85 27
Azospirillum brasilense Sp245 0.48 AZOBR_RS06140 phosphoribosylaminoimidazole carboxylase 0.59 AZOBR_RS08310 amidophosphoribosyltransferase — —
Bosea sp. OAE506 0.48 ABIE41_RS09245 5-(carboxyamino)imidazole ribonucleotide synthase 0.54 ABIE41_RS17810 amidophosphoribosyltransferase 0.34 16
Rhodopseudomonas palustris CGA009 0.45 TX73_021645 5-(carboxyamino)imidazole ribonucleotide synthase 0.54 TX73_015990 amidophosphoribosyltransferase — —
Magnetospirillum magneticum AMB-1 0.45 AMB_RS11140 5-(carboxyamino)imidazole ribonucleotide synthase 0.59 AMB_RS10545 amidophosphoribosyltransferase — —
Sphingomonas koreensis DSMZ 15582 0.45 Ga0059261_1428 5-(carboxyamino)imidazole ribonucleotide synthase 0.57 Ga0059261_3626 amidophosphoribosyltransferase (EC 2.4.2.14) — —
Rhodospirillum rubrum S1H 0.45 Rru_A1051 Phosphoribosylaminoimidazole carboxylase, ATPase subunit (NCBI) 0.60 Rru_A0404 Amidophosphoribosyl transferase (NCBI) low > 58
Brevundimonas sp. GW460-12-10-14-LB2 0.45 A4249_RS08935 5-(carboxyamino)imidazole ribonucleotide synthase 0.52 A4249_RS03735 amidophosphoribosyltransferase — —
Azospirillum sp. SherDot2 0.42 MPMX19_01418 N5-carboxyaminoimidazole ribonucleotide synthase 0.58 MPMX19_00906 Amidophosphoribosyltransferase — —
Herbaspirillum seropedicae SmR1 0.37 HSERO_RS03370 phosphoribosylaminoimidazole carboxylase 0.31 HSERO_RS16445 amidophosphoribosyltransferase — —
Pseudomonas sp. RS175 0.37 PFR28_04495 N5-carboxyaminoimidazole ribonucleotide synthase 0.28 PFR28_02811 Amidophosphoribosyltransferase — —
Pseudomonas putida KT2440 0.37 PP_5335 N5-carboxyaminoimidazole ribonucleotide synthase 0.28 PP_2000 amidophosphoribosyl transferase — —
Pseudomonas stutzeri RCH2 0.37 Psest_4068 phosphoribosylaminoimidazole carboxylase, PurK protein 0.27 Psest_2579 amidophosphoribosyltransferase — —
Pseudomonas fluorescens FW300-N2E2 0.36 Pf6N2E2_4081 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.28 Pf6N2E2_76 Amidophosphoribosyltransferase (EC 2.4.2.14) — —
Paraburkholderia bryophila 376MFSha3.1 0.36 H281DRAFT_04185 5-(carboxyamino)imidazole ribonucleotide synthase 0.30 H281DRAFT_06060 amidophosphoribosyltransferase — —
Paraburkholderia graminis OAS925 0.36 ABIE53_003423 5-(carboxyamino)imidazole ribonucleotide synthase 0.29 ABIE53_004816 amidophosphoribosyltransferase — —
Xanthomonas campestris pv. campestris strain 8004 0.36 Xcc-8004.2012.1 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.29 Xcc-8004.4073.1 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.91 3
Burkholderia phytofirmans PsJN 0.36 BPHYT_RS16245 phosphoribosylaminoimidazole carboxylase 0.30 BPHYT_RS33840 amidophosphoribosyltransferase 0.86 2
Dechlorosoma suillum PS 0.36 Dsui_0091 phosphoribosylaminoimidazole carboxylase, PurK protein 0.32 Dsui_3186 amidophosphoribosyltransferase — —
Lysobacter sp. OAE881 0.36 ABIE51_RS15390 5-(carboxyamino)imidazole ribonucleotide synthase 0.28 ABIE51_RS06180 amidophosphoribosyltransferase low > 62
Paraburkholderia sabiae LMG 24235 0.36 QEN71_RS02450 5-(carboxyamino)imidazole ribonucleotide synthase 0.29 QEN71_RS17680 amidophosphoribosyltransferase 0.63 15
Pseudomonas fluorescens FW300-N2C3 0.36 AO356_11075 phosphoribosylaminoimidazole carboxylase 0.28 AO356_21465 amidophosphoribosyltransferase — —
Pseudomonas sp. S08-1 0.35 OH686_13380 N5-carboxyaminoimidazole ribonucleotide synthase 0.28 OH686_04420 amidophosphoribosyltransferase — —
Pseudomonas fluorescens GW456-L13 0.35 PfGW456L13_747 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.28 PfGW456L13_3935 Amidophosphoribosyltransferase (EC 2.4.2.14) — —
Marinobacter adhaerens HP15 0.35 HP15_2350 phosphoribosylaminoimidazole carboxylase ATPase subunit 0.28 HP15_1821 amidophosphoribosyltransferase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.35 Psyr_5047 5-(carboxyamino)imidazole ribonucleotide synthase 0.28 Psyr_1668 amidophosphoribosyltransferase — —
Pseudomonas syringae pv. syringae B728a 0.35 Psyr_5047 5-(carboxyamino)imidazole ribonucleotide synthase 0.28 Psyr_1668 amidophosphoribosyltransferase — —
Pseudomonas fluorescens SBW25 0.34 PFLU_RS29800 5-(carboxyamino)imidazole ribonucleotide synthase 0.28 PFLU_RS20515 amidophosphoribosyltransferase — —
Pseudomonas simiae WCS417 0.34 PS417_28115 phosphoribosylaminoimidazole carboxylase 0.28 PS417_18535 amidophosphoribosyltransferase — —
Pseudomonas fluorescens FW300-N2E3 0.34 AO353_09935 phosphoribosylaminoimidazole carboxylase 0.28 AO353_20690 amidophosphoribosyltransferase — —
Pseudomonas fluorescens SBW25-INTG 0.34 PFLU_RS29800 5-(carboxyamino)imidazole ribonucleotide synthase 0.28 PFLU_RS20515 amidophosphoribosyltransferase — —
Acinetobacter radioresistens SK82 0.34 MPMX26_03050 N5-carboxyaminoimidazole ribonucleotide synthase 0.26 MPMX26_01122 Amidophosphoribosyltransferase 0.89 5
Variovorax sp. SCN45 0.34 GFF5513 N5-carboxyaminoimidazole ribonucleotide synthase (EC 6.3.4.18) 0.29 GFF3089 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.90 28
Hydrogenophaga sp. GW460-11-11-14-LB1 0.34 GFF2770 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.29 GFF300 Amidophosphoribosyltransferase (EC 2.4.2.14) — —
Rhodanobacter sp. FW510-T8 0.33 OKGIIK_03050 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.30 OKGIIK_05570 purF amidophosphoribosyltransferase — —
Bifidobacterium breve UCC2003 0.33 BBR_RS13300 5-(carboxyamino)imidazole ribonucleotide synthase 0.43 BBR_RS13380 amidophosphoribosyltransferase low > 34
Cupriavidus basilensis FW507-4G11 0.33 RR42_RS03230 phosphoribosylaminoimidazole carboxylase 0.28 RR42_RS14325 amidophosphoribosyltransferase — —
Dyella japonica UNC79MFTsu3.2 0.32 ABZR86_RS09830 5-(carboxyamino)imidazole ribonucleotide synthase 0.29 ABZR86_RS06775 amidophosphoribosyltransferase — —
Variovorax sp. OAS795 0.32 ABID97_RS01700 5-(carboxyamino)imidazole ribonucleotide synthase 0.29 ABID97_RS21635 amidophosphoribosyltransferase — —
Acidovorax sp. GW101-3H11 0.32 Ac3H11_675 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.30 Ac3H11_2608 Amidophosphoribosyltransferase (EC 2.4.2.14) — —
Castellaniella sp019104865 MT123 0.32 ABCV34_RS00565 5-(carboxyamino)imidazole ribonucleotide synthase 0.28 ABCV34_RS04130 amidophosphoribosyltransferase — —
Ralstonia solanacearum PSI07 0.32 RPSI07_RS21130 5-(carboxyamino)imidazole ribonucleotide synthase 0.30 RPSI07_RS14765 amidophosphoribosyltransferase — —
Ralstonia solanacearum GMI1000 0.31 RS_RS02885 5-(carboxyamino)imidazole ribonucleotide synthase 0.30 RS_RS09930 amidophosphoribosyltransferase — —
Ralstonia solanacearum UW163 0.31 UW163_RS01410 5-(carboxyamino)imidazole ribonucleotide synthase 0.30 UW163_RS11175 amidophosphoribosyltransferase — —
Ralstonia solanacearum IBSBF1503 0.31 RALBFv3_RS12200 5-(carboxyamino)imidazole ribonucleotide synthase 0.30 RALBFv3_RS02550 amidophosphoribosyltransferase — —
Rhodanobacter denitrificans MT42 0.31 LRK55_RS13530 5-(carboxyamino)imidazole ribonucleotide synthase 0.30 LRK55_RS01105 amidophosphoribosyltransferase low > 63
Ralstonia sp. UNC404CL21Col 0.31 ABZR87_RS08090 5-(carboxyamino)imidazole ribonucleotide synthase 0.29 ABZR87_RS14465 amidophosphoribosyltransferase — —
Rhodanobacter denitrificans FW104-10B01 0.31 LRK54_RS13815 5-(carboxyamino)imidazole ribonucleotide synthase 0.30 LRK54_RS01340 amidophosphoribosyltransferase — —
Pantoea sp. MT58 0.30 IAI47_14355 5-(carboxyamino)imidazole ribonucleotide synthase 0.31 IAI47_06275 amidophosphoribosyltransferase 0.97 2
Kangiella aquimarina DSM 16071 0.29 B158DRAFT_0610 5-(carboxyamino)imidazole ribonucleotide synthase 0.28 B158DRAFT_1488 amidophosphoribosyltransferase (EC 2.4.2.14) — —
Escherichia coli ECOR27 0.29 NOLOHH_00830 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.29 NOLOHH_14335 purF amidophosphoribosyltransferase low > 57
Escherichia coli Nissle 1917 0.29 ECOLIN_RS03025 5-(carboxyamino)imidazole ribonucleotide synthase 0.29 ECOLIN_RS13405 amidophosphoribosyltransferase — —
Escherichia coli BL21 0.29 ECD_00472 N5-carboxyaminoimidazole ribonucleotide synthase 0.29 ECD_02237 amidophosphoribosyltransferase 0.67 10
Synechococcus elongatus PCC 7942 0.29 Synpcc7942_1428 purK phosphoribosylaminoimidazole carboxylase ATPase subunit 0.40 Synpcc7942_0004 purF amidophosphoribosyltransferase — —
Escherichia coli ECOR38 0.29 HEPCGN_06480 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.29 HEPCGN_21910 purF amidophosphoribosyltransferase low > 85
Escherichia fergusonii Becca 0.29 EFB2_03540 N5-carboxyaminoimidazole ribonucleotide synthase 0.29 EFB2_01546 Amidophosphoribosyltransferase low > 86
Escherichia coli ECRC62 0.29 BNILDI_22260 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.29 BNILDI_13255 purF amidophosphoribosyltransferase — —
Escherichia coli ECRC101 0.28 MCAODC_27060 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.29 MCAODC_13755 purF amidophosphoribosyltransferase — —
Escherichia coli ECRC101 0.28 OKFHMN_07840 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.29 OKFHMN_22715 purF amidophosphoribosyltransferase — —
Escherichia coli ECRC98 0.28 JDDGAC_11490 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.29 JDDGAC_26675 purF amidophosphoribosyltransferase — —
Escherichia coli BW25113 0.28 b0522 purK phosphoribosylaminoimidazole carboxylase (NCBI) 0.29 b2312 purF amidophosphoribosyltransferase (NCBI) 0.95 4
Escherichia coli ECRC99 0.28 KEDOAH_20130 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.29 KEDOAH_05480 purF amidophosphoribosyltransferase — —
Escherichia coli ECRC102 0.28 NIAGMN_05895 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.29 NIAGMN_20485 purF amidophosphoribosyltransferase — —
Enterobacter asburiae PDN3 0.28 EX28DRAFT_2460 phosphoribosylaminoimidazole carboxylase, PurK protein 0.30 EX28DRAFT_0292 amidophosphoribosyltransferase (EC 2.4.2.14) — —
Shewanella loihica PV-4 0.28 Shew_1249 phosphoribosylaminoimidazole carboxylase, ATPase subunit (RefSeq) 0.29 Shew_2302 amidophosphoribosyltransferase (RefSeq) 0.64 60
Vibrio cholerae E7946 ATCC 55056 0.28 CSW01_00260 5-(carboxyamino)imidazole ribonucleotide synthase 0.28 CSW01_05115 amidophosphoribosyltransferase low > 62
Escherichia coli HS(pFamp)R (ATCC 700891) 0.28 OHPLBJKB_03159 N5-carboxyaminoimidazole ribonucleotide synthase 0.29 OHPLBJKB_01393 Amidophosphoribosyltransferase 0.47 5
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.28 GFF4438 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.31 GFF1927 Amidophosphoribosyltransferase (EC 2.4.2.14) low > 78
Rahnella sp. WP5 0.28 EX31_RS22620 5-(carboxyamino)imidazole ribonucleotide synthase 0.29 EX31_RS19570 amidophosphoribosyltransferase 0.96 1
Enterobacter sp. TBS_079 0.28 MPMX20_01097 N5-carboxyaminoimidazole ribonucleotide synthase 0.30 MPMX20_03247 Amidophosphoribosyltransferase 0.95 5
Klebsiella michiganensis M5al 0.28 BWI76_RS07065 5-(carboxyamino)imidazole ribonucleotide synthase 0.30 BWI76_RS20350 amidophosphoribosyltransferase 0.89 4
Erwinia tracheiphila SCR3 0.27 LU632_RS15250 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.30 LU632_RS07865 purF amidophosphoribosyltransferase 0.90 2
Alteromonas macleodii MIT1002 0.26 MIT1002_00522 N5-carboxyaminoimidazole ribonucleotide synthase 0.30 MIT1002_02524 Amidophosphoribosyltransferase 0.98 23
Serratia liquefaciens MT49 0.26 IAI46_05370 5-(carboxyamino)imidazole ribonucleotide synthase 0.31 IAI46_17810 amidophosphoribosyltransferase low > 86
Dickeya dianthicola 67-19 0.25 HGI48_RS15190 5-(carboxyamino)imidazole ribonucleotide synthase 0.30 HGI48_RS14405 amidophosphoribosyltransferase 0.77 6
Mycobacterium tuberculosis H37Rv 0.25 Rv3276c Probable phosphoribosylaminoimidazole carboxylase ATPase subunit PurK (air carboxylase) (AIRC) 0.38 Rv0808 Amidophosphoribosyltransferase PurF (glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (gpatase) — —
Dickeya dianthicola ME23 0.25 DZA65_RS15995 5-(carboxyamino)imidazole ribonucleotide synthase 0.30 DZA65_RS15335 amidophosphoribosyltransferase 0.89 4
Pectobacterium carotovorum WPP14 0.25 HER17_RS06470 5-(carboxyamino)imidazole ribonucleotide synthase 0.30 HER17_RS07020 amidophosphoribosyltransferase 0.92 42
Shewanella oneidensis MR-1 0.25 SO3555 purK phosphoribosylaminoimidazole carboxylase, ATPase subunit (NCBI ptt file) 0.29 SO3064 purF amidophosphoribosyltransferase (NCBI ptt file) 0.95 7
Dickeya dadantii 3937 0.25 DDA3937_RS15110 5-(carboxyamino)imidazole ribonucleotide synthase 0.30 DDA3937_RS14435 amidophosphoribosyltransferase 0.82 14
Shewanella amazonensis SB2B 0.25 Sama_1063 phosphoribosylaminoimidazole carboxylase ATPase subunit (RefSeq) 0.29 Sama_2146 amidophosphoribosyltransferase (RefSeq) 0.94 6
Shewanella sp. ANA-3 0.24 Shewana3_3156 phosphoribosylaminoimidazole carboxylase ATPase subunit (RefSeq) 0.29 Shewana3_1483 amidophosphoribosyltransferase (RefSeq) 0.94 5
Methanococcus maripaludis S2 0.19 MMP_RS00715 formate-dependent phosphoribosylglycinamide formyltransferase 0.37 MMP_RS05915 amidophosphoribosyltransferase — —
Methanococcus maripaludis JJ 0.18 MMJJ_RS04770 formate-dependent phosphoribosylglycinamide formyltransferase 0.39 MMJJ_RS08440 amidophosphoribosyltransferase — —
Desulfovibrio vulgaris Hildenborough JW710 0.17 DVU0723 purT phosphoribosylglycinamide formyltransferase 2 (TIGR) 0.42 DVU0161 purF amidophosphoribosyltransferase (TIGR) — —
Desulfovibrio vulgaris Miyazaki F 0.16 DvMF_2756 purT phosphoribosylglycinamide formyltransferase 2 (RefSeq) 0.41 DvMF_2307 amidophosphoribosyltransferase (RefSeq) low > 51
Phocaeicola vulgatus CL09T03C04 0.16 HMPREF1058_RS17920 formate-dependent phosphoribosylglycinamide formyltransferase 0.19 HMPREF1058_RS04675 amidophosphoribosyltransferase low > 67
Phocaeicola dorei CL03T12C01 0.16 ABI39_RS14185 formate-dependent phosphoribosylglycinamide formyltransferase 0.18 ABI39_RS18960 amidophosphoribosyltransferase low > 72
Bacteroides stercoris CC31F 0.15 HMPREF1181_RS16250 formate-dependent phosphoribosylglycinamide formyltransferase 0.17 HMPREF1181_RS13265 amidophosphoribosyltransferase low > 56
Parabacteroides merdae CL09T00C40 0.15 HMPREF1078_RS10980 formate-dependent phosphoribosylglycinamide formyltransferase 0.18 HMPREF1078_RS10430 amidophosphoribosyltransferase low > 61
Bacteroides thetaiotaomicron VPI-5482 0.15 BT0704 phosphoribosylglycinamide formyltransferase 2 (NCBI ptt file) 0.18 BT4582 amidophosphoribosyltransferase precursor (NCBI ptt file) low > 81
Bacteroides ovatus ATCC 8483 0.14 BACOVA_02411 phosphoribosylglycinamide formyltransferase 2 0.18 BACOVA_05376 putative amidophosphoribosyltransferase low > 94

Not shown: 5 genomes with orthologs for PGA1_c24870 only; 1 genomes with orthologs for PGA1_c10810 only