Conservation of cofitness between Atu1308 and Atu2264 in Agrobacterium fabrum C58

93 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Agrobacterium fabrum C58 1.0 Atu1308 aspartate carbamoyl transferase catalytic subunit 1.0 Atu2264 2-isopropylmalate synthase 0.87 15
Sinorhizobium meliloti 1021 0.91 SMc01360 aspartate carbamoyltransferase catalytic subunit 0.88 SMc02717 2-isopropylmalate synthase 0.84 24
Rhizobium sp. OAE497 0.89 ABIE40_RS07385 aspartate carbamoyltransferase catalytic subunit 0.87 ABIE40_RS13330 2-isopropylmalate synthase — —
Bosea sp. OAE506 0.75 ABIE41_RS17230 aspartate carbamoyltransferase catalytic subunit 0.11 ABIE41_RS13000 2-isopropylmalate synthase low > 77
Rhodopseudomonas palustris CGA009 0.68 TX73_016120 aspartate carbamoyltransferase catalytic subunit 0.50 TX73_024250 2-isopropylmalate synthase — —
Rhodospirillum rubrum S1H 0.67 Rru_A3190 Aspartate carbamoyltransferase (NCBI) 0.59 Rru_A1928 Yeast 2-isopropylmalate synthase (NCBI) 0.55 19
Magnetospirillum magneticum AMB-1 0.67 AMB_RS18300 aspartate carbamoyltransferase 0.55 AMB_RS17550 2-isopropylmalate synthase — —
Azospirillum sp. SherDot2 0.67 MPMX19_01054 Aspartate carbamoyltransferase 0.59 MPMX19_01822 2-isopropylmalate synthase 0.78 27
Azospirillum brasilense Sp245 0.66 AZOBR_RS20575 aspartate carbamoyltransferase 0.58 AZOBR_RS12155 2-isopropylmalate synthase 0.64 7
Phaeobacter inhibens DSM 17395 0.65 PGA1_c03060 aspartate carbamoyltransferase PyrB 0.11 PGA1_c26470 2-isopropylmalate synthase LeuA 0.88 11
Dinoroseobacter shibae DFL-12 0.64 Dshi_3091 aspartate carbamoyltransferase (RefSeq) 0.12 Dshi_0596 2-isopropylmalate synthase (RefSeq) 0.77 18
Sphingomonas koreensis DSMZ 15582 0.61 Ga0059261_0076 aspartate carbamoyltransferase (EC 2.1.3.2) 0.51 Ga0059261_4031 2-isopropylmalate synthase, yeast type — —
Caulobacter crescentus NA1000 0.61 CCNA_02525 aspartate carbamoyltransferase 0.10 CCNA_01610 2-isopropylmalate synthase low > 66
Caulobacter crescentus NA1000 Δfur 0.61 CCNA_02525 aspartate carbamoyltransferase 0.10 CCNA_01610 2-isopropylmalate synthase low > 67
Ralstonia solanacearum IBSBF1503 0.53 RALBFv3_RS12625 aspartate carbamoyltransferase catalytic subunit 0.53 RALBFv3_RS21840 2-isopropylmalate synthase — —
Cupriavidus basilensis FW507-4G11 0.53 RR42_RS15860 aspartate carbamoyltransferase catalytic subunit 0.49 RR42_RS21205 2-isopropylmalate synthase — —
Ralstonia solanacearum UW163 0.53 UW163_RS00940 aspartate carbamoyltransferase catalytic subunit 0.53 UW163_RS17345 2-isopropylmalate synthase — —
Ralstonia solanacearum PSI07 0.53 RPSI07_RS20635 aspartate carbamoyltransferase catalytic subunit 0.52 RPSI07_RS01320 2-isopropylmalate synthase — —
Ralstonia sp. UNC404CL21Col 0.53 ABZR87_RS08625 aspartate carbamoyltransferase catalytic subunit 0.52 ABZR87_RS22365 2-isopropylmalate synthase low > 80
Ralstonia solanacearum GMI1000 0.53 RS_RS03410 aspartate carbamoyltransferase 0.51 RS_RS18695 2-isopropylmalate synthase 2 — —
Pseudomonas stutzeri RCH2 0.52 Psest_0291 aspartate carbamoyltransferase 0.55 Psest_1277 2-isopropylmalate synthase, yeast type — —
Paraburkholderia graminis OAS925 0.52 ABIE53_001131 aspartate carbamoyltransferase catalytic subunit 0.50 ABIE53_002867 2-isopropylmalate synthase low > 113
Paraburkholderia bryophila 376MFSha3.1 0.52 H281DRAFT_04817 aspartate carbamoyltransferase 0.51 H281DRAFT_00385 2-isopropylmalate synthase low > 103
Pseudomonas sp. S08-1 0.52 OH686_10940 aspartate carbamoyltransferase 0.52 OH686_17570 2-isopropylmalate synthase — —
Burkholderia phytofirmans PsJN 0.52 BPHYT_RS04235 aspartate carbamoyltransferase 0.50 BPHYT_RS13280 2-isopropylmalate synthase low > 109
Marinobacter adhaerens HP15 0.52 HP15_3507 aspartate carbamoyltransferase 0.48 HP15_2055 2-isopropylmalate synthase low > 73
Variovorax sp. SCN45 0.51 GFF2160 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.50 GFF1164 2-isopropylmalate synthase (EC 2.3.3.13) low > 127
Acidovorax sp. GW101-3H11 0.51 Ac3H11_3978 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.46 Ac3H11_5000 2-isopropylmalate synthase (EC 2.3.3.13) — —
Dechlorosoma suillum PS 0.51 Dsui_0596 aspartate carbamoyltransferase 0.51 Dsui_3227 2-isopropylmalate synthase — —
Pseudomonas simiae WCS417 0.51 PS417_26700 aspartate carbamoyltransferase catalytic subunit 0.53 PS417_23110 2-isopropylmalate synthase — —
Pseudomonas fluorescens FW300-N2E3 0.51 AO353_08135 aspartate carbamoyltransferase catalytic subunit 0.53 AO353_15925 2-isopropylmalate synthase — —
Pseudomonas fluorescens FW300-N2C3 0.51 AO356_13450 aspartate carbamoyltransferase catalytic subunit 0.53 AO356_06550 2-isopropylmalate synthase — —
Pseudomonas fluorescens FW300-N2E2 0.51 Pf6N2E2_4606 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.53 Pf6N2E2_3170 2-isopropylmalate synthase (EC 2.3.3.13) — —
Pseudomonas fluorescens GW456-L13 0.51 PfGW456L13_1016 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.52 PfGW456L13_4854 2-isopropylmalate synthase (EC 2.3.3.13) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.51 Psyr_0482 aspartate carbamoyltransferase 0.53 Psyr_1257 2-isopropylmalate synthase — —
Pseudomonas sp. RS175 0.51 PFR28_04237 Aspartate carbamoyltransferase 0.53 PFR28_00305 2-isopropylmalate synthase — —
Pseudomonas fluorescens SBW25 0.51 PFLU_RS28345 aspartate carbamoyltransferase 0.53 PFLU_RS24765 2-isopropylmalate synthase — —
Desulfovibrio vulgaris Hildenborough JW710 0.51 DVU2901 pyrB aspartate carbamoyltransferase (TIGR) 0.12 DVU2981 leuA 2-isopropylmalate synthase (TIGR) — —
Pseudomonas fluorescens FW300-N1B4 0.51 Pf1N1B4_2347 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.53 Pf1N1B4_847 2-isopropylmalate synthase (EC 2.3.3.13) — —
Pseudomonas fluorescens SBW25-INTG 0.51 PFLU_RS28345 aspartate carbamoyltransferase 0.53 PFLU_RS24765 2-isopropylmalate synthase — —
Pseudomonas syringae pv. syringae B728a 0.51 Psyr_0482 aspartate carbamoyltransferase 0.53 Psyr_1257 2-isopropylmalate synthase — —
Variovorax sp. OAS795 0.50 ABID97_RS24660 aspartate carbamoyltransferase catalytic subunit 0.50 ABID97_RS14905 2-isopropylmalate synthase low > 91
Hydrogenophaga sp. GW460-11-11-14-LB1 0.50 GFF651 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.50 GFF4280 2-isopropylmalate synthase (EC 2.3.3.13) low > 90
Pseudomonas putida KT2440 0.50 PP_4998 Aspartate carbamoyltransferase 0.54 PP_1025 2-isopropylmalate synthase — —
Herbaspirillum seropedicae SmR1 0.50 HSERO_RS02330 aspartate carbamoyltransferase 0.52 HSERO_RS17185 2-isopropylmalate synthase 0.50 25
Desulfovibrio vulgaris Miyazaki F 0.47 DvMF_1425 pyrB aspartate carbamoyltransferase catalytic subunit (RefSeq) 0.13 DvMF_1791 2-isopropylmalate synthase (RefSeq) 0.66 50
Mycobacterium tuberculosis H37Rv 0.46 Rv1380 Probable aspartate carbamoyltransferase PyrB (ATCase) (aspartate transcarbamylase) 0.52 Rv3710 2-isopropylmalate synthase LeuA (alpha-isopropylmalate synthase) (alpha-IPM synthetase) (IPMS) — —
Acinetobacter radioresistens SK82 0.46 MPMX26_01099 Aspartate carbamoyltransferase 0.50 MPMX26_00404 2-isopropylmalate synthase low > 36
Rhodanobacter sp. FW510-T8 0.43 OKGIIK_11095 pyrB aspartate carbamoyltransferase catalytic subunit 0.10 OKGIIK_13575 leuA 2-isopropylmalate synthase — —
Dyella japonica UNC79MFTsu3.2 0.42 ABZR86_RS10390 aspartate carbamoyltransferase catalytic subunit 0.11 ABZR86_RS15970 2-isopropylmalate synthase — —
Rhodanobacter denitrificans MT42 0.42 LRK55_RS03990 aspartate carbamoyltransferase catalytic subunit 0.10 LRK55_RS09985 2-isopropylmalate synthase — —
Rhodanobacter denitrificans FW104-10B01 0.42 LRK54_RS04220 aspartate carbamoyltransferase catalytic subunit 0.10 LRK54_RS10345 2-isopropylmalate synthase — —
Xanthomonas campestris pv. campestris strain 8004 0.42 Xcc-8004.1722.1 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.11 Xcc-8004.1056.1 2-isopropylmalate synthase (EC 2.3.3.13) — —
Lysobacter sp. OAE881 0.41 ABIE51_RS16015 aspartate carbamoyltransferase catalytic subunit 0.11 ABIE51_RS17570 2-isopropylmalate synthase low > 62
Synechococcus elongatus PCC 7942 0.41 Synpcc7942_0670 pyrB aspartate carbamoyltransferase catalytic subunit 0.09 Synpcc7942_1410 leuA 2-isopropylmalate synthase — —
Methanococcus maripaludis JJ 0.24 MMJJ_RS05825 aspartate carbamoyltransferase 0.10 MMJJ_RS08870 2-isopropylmalate synthase — —
Methanococcus maripaludis S2 0.24 MMP_RS08545 aspartate carbamoyltransferase 0.10 MMP_RS05500 2-isopropylmalate synthase — —
Bifidobacterium breve UCC2003 0.23 BBR_RS15425 aspartate carbamoyltransferase 0.50 BBR_RS11170 2-isopropylmalate synthase low > 34
Escherichia coli ECOR38 0.23 HEPCGN_10060 pyrB aspartate carbamoyltransferase 0.09 HEPCGN_08695 2-isopropylmalate synthase low > 85
Escherichia coli ECRC101 0.23 MCAODC_02370 pyrB aspartate carbamoyltransferase 0.09 MCAODC_01230 2-isopropylmalate synthase — —
Escherichia coli ECRC99 0.23 KEDOAH_16290 pyrB aspartate carbamoyltransferase 0.09 KEDOAH_17440 2-isopropylmalate synthase — —
Escherichia coli ECRC98 0.23 JDDGAC_15505 pyrB aspartate carbamoyltransferase 0.09 JDDGAC_14310 2-isopropylmalate synthase — —
Escherichia coli BL21 0.23 ECD_04113 aspartate carbamoyltransferase, catalytic subunit 0.09 ECD_00076 2-isopropylmalate synthase low > 60
Escherichia coli Nissle 1917 0.23 ECOLIN_RS24625 aspartate carbamoyltransferase 0.09 ECOLIN_RS00400 2-isopropylmalate synthase low > 52
Escherichia coli ECRC62 0.23 BNILDI_07385 pyrB aspartate carbamoyltransferase 0.09 BNILDI_08550 2-isopropylmalate synthase — —
Escherichia coli BW25113 0.23 b4245 pyrB aspartate carbamoyltransferase catalytic subunit (NCBI) 0.09 b0074 leuA 2-isopropylmalate synthase (NCBI) 0.72 62
Escherichia coli HS(pFamp)R (ATCC 700891) 0.23 OHPLBJKB_03789 Aspartate carbamoyltransferase catalytic subunit 0.09 OHPLBJKB_03583 2-isopropylmalate synthase low > 73
Escherichia coli ECRC101 0.23 OKFHMN_11865 pyrB aspartate carbamoyltransferase 0.09 OKFHMN_10715 2-isopropylmalate synthase — —
Escherichia fergusonii Becca 0.23 EFB2_04288 Aspartate carbamoyltransferase catalytic subunit 0.09 EFB2_03971 2-isopropylmalate synthase low > 86
Escherichia coli ECRC102 0.23 NIAGMN_09715 pyrB aspartate carbamoyltransferase 0.09 NIAGMN_08565 2-isopropylmalate synthase — —
Escherichia coli ECOR27 0.23 NOLOHH_04125 pyrB aspartate carbamoyltransferase 0.09 NOLOHH_03060 2-isopropylmalate synthase low > 57
Enterobacter asburiae PDN3 0.22 EX28DRAFT_3446 aspartate carbamoyltransferase (EC 2.1.3.2) 0.46 EX28DRAFT_2770 2-isopropylmalate synthase, yeast type — —
Klebsiella michiganensis M5al 0.22 BWI76_RS02995 aspartate carbamoyltransferase 0.46 BWI76_RS22105 2-isopropylmalate synthase low > 92
Enterobacter sp. TBS_079 0.22 MPMX20_00544 Aspartate carbamoyltransferase catalytic subunit 0.46 MPMX20_03565 2-isopropylmalate synthase low > 85
Pantoea sp. MT58 0.22 IAI47_16860 aspartate carbamoyltransferase 0.44 IAI47_10235 2-isopropylmalate synthase low > 76
Serratia liquefaciens MT49 0.22 IAI46_02275 aspartate carbamoyltransferase 0.49 IAI46_09630 2-isopropylmalate synthase low > 86
Dickeya dadantii 3937 0.22 DDA3937_RS01925 aspartate carbamoyltransferase 0.45 DDA3937_RS02895 2-isopropylmalate synthase low > 74
Parabacteroides merdae CL09T00C40 0.22 HMPREF1078_RS01350 aspartate carbamoyltransferase 0.12 HMPREF1078_RS16665 2-isopropylmalate synthase — —
Erwinia tracheiphila SCR3 0.22 LU632_RS20950 pyrB aspartate carbamoyltransferase 0.11 LU632_RS02880 leuA 2-isopropylmalate synthase low > 74
Dickeya dianthicola ME23 0.22 DZA65_RS01970 aspartate carbamoyltransferase 0.10 DZA65_RS19200 2-isopropylmalate synthase 0.91 5
Vibrio cholerae E7946 ATCC 55056 0.21 CSW01_12725 aspartate carbamoyltransferase 0.10 CSW01_12595 2-isopropylmalate synthase low > 62
Pectobacterium carotovorum WPP14 0.21 HER17_RS19510 aspartate carbamoyltransferase 0.10 HER17_RS03085 2-isopropylmalate synthase 0.98 1
Dickeya dianthicola 67-19 0.21 HGI48_RS01900 aspartate carbamoyltransferase 0.09 HGI48_RS18055 2-isopropylmalate synthase 0.76 19
Phocaeicola dorei CL03T12C01 0.21 ABI39_RS17400 aspartate carbamoyltransferase 0.10 ABI39_RS10195 2-isopropylmalate synthase — —
Phocaeicola vulgatus CL09T03C04 0.21 HMPREF1058_RS03820 aspartate carbamoyltransferase 0.10 HMPREF1058_RS14545 2-isopropylmalate synthase — —
Alteromonas macleodii MIT1002 0.21 MIT1002_00423 Aspartate carbamoyltransferase catalytic chain 0.09 MIT1002_00949 2-isopropylmalate synthase 0.83 53
Rahnella sp. WP5 0.21 EX31_RS12785 aspartate carbamoyltransferase 0.50 EX31_RS24130 2-isopropylmalate synthase low > 89
Bacteroides stercoris CC31F 0.21 HMPREF1181_RS14990 aspartate carbamoyltransferase 0.11 HMPREF1181_RS14150 2-isopropylmalate synthase 0.87 40
Bacteroides ovatus ATCC 8483 0.21 BACOVA_02450 aspartate carbamoyltransferase 0.10 BACOVA_04604 2-isopropylmalate synthase — —
Bacteroides thetaiotaomicron VPI-5482 0.21 BT0742 aspartate carbamoyltransferase catalytic chain (NCBI ptt file) 0.10 BT1861 2-isopropylmalate synthase (EC 2.3.3.13) (from data) — —
Shewanella oneidensis MR-1 0.20 SO1301 pyrB aspartate carbamoyltransferase (NCBI ptt file) 0.09 SO4236 leuA 2-isopropylmalate synthase (NCBI ptt file) 0.81 30
Shewanella sp. ANA-3 0.20 Shewana3_3070 aspartate carbamoyltransferase (RefSeq) 0.09 Shewana3_3761 2-isopropylmalate synthase (RefSeq) 0.86 44
Shewanella loihica PV-4 0.20 Shew_1013 aspartate carbamoyltransferase (RefSeq) 0.09 Shew_3472 2-isopropylmalate synthase (RefSeq) 0.80 46
Shewanella amazonensis SB2B 0.19 Sama_0840 aspartate carbamoyltransferase (RefSeq) 0.09 Sama_0335 2-isopropylmalate synthase (RefSeq) 0.55 41

Not shown: 9 genomes with orthologs for Atu1308 only; 1 genomes with orthologs for Atu2264 only