Conservation of cofitness between BT2077 and BT3718 in Bacteroides thetaiotaomicron VPI-5482

99 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bacteroides thetaiotaomicron VPI-5482 1.0 BT2077 acetolactate synthase large subunit (NCBI ptt file) 1.0 BT3718 gamma-glutamyl phosphate reductase (NCBI ptt file) 0.94 8
Bacteroides ovatus ATCC 8483 0.92 BACOVA_03303 acetolactate synthase, large subunit, biosynthetic type 0.90 BACOVA_03534 glutamate-5-semialdehyde dehydrogenase 0.96 9
Bacteroides stercoris CC31F 0.87 HMPREF1181_RS08330 biosynthetic-type acetolactate synthase large subunit 0.73 HMPREF1181_RS03320 glutamate-5-semialdehyde dehydrogenase 0.87 18
Phocaeicola dorei CL03T12C01 0.85 ABI39_RS12720 biosynthetic-type acetolactate synthase large subunit 0.62 ABI39_RS02875 glutamate-5-semialdehyde dehydrogenase 0.87 15
Phocaeicola vulgatus CL09T03C04 0.84 HMPREF1058_RS16820 biosynthetic-type acetolactate synthase large subunit 0.61 HMPREF1058_RS08645 glutamate-5-semialdehyde dehydrogenase 0.88 13
Parabacteroides merdae CL09T00C40 0.66 HMPREF1078_RS16690 biosynthetic-type acetolactate synthase large subunit 0.68 HMPREF1078_RS10655 glutamate-5-semialdehyde dehydrogenase low > 61
Mucilaginibacter yixingensis YX-36 DSM 26809 0.58 ABZR88_RS11580 biosynthetic-type acetolactate synthase large subunit 0.60 ABZR88_RS22165 glutamate-5-semialdehyde dehydrogenase 0.77 16
Pontibacter actiniarum KMM 6156, DSM 19842 0.57 CA264_06930 acetolactate synthase, large subunit, biosynthetic type 0.64 CA264_07720 gamma-glutamyl-phosphate reductase low > 74
Pedobacter sp. GW460-11-11-14-LB5 0.57 CA265_RS15805 acetolactate synthase, large subunit, biosynthetic type 0.58 CA265_RS20850 glutamate-5-semialdehyde dehydrogenase 0.92 29
Echinicola vietnamensis KMM 6221, DSM 17526 0.56 Echvi_2056 acetolactate synthase, large subunit, biosynthetic type 0.28 Echvi_2633 gamma-glutamylphosphate reductase (EC 1.2.1.41) (from data) 0.87 38
Desulfovibrio vulgaris Hildenborough JW710 0.43 DVU1376 ilvB-2 acetolactate synthase, large subunit, biosynthetic type (TIGR) 0.32 DVU1953 proA gamma-glutamyl phosphate reductase (TIGR) 0.82 16
Enterobacter asburiae PDN3 0.43 EX28DRAFT_4440 acetolactate synthase, large subunit (EC 2.2.1.6) 0.38 EX28DRAFT_2650 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) low > 76
Escherichia coli ECRC101 0.43 MCAODC_05160 ilvG acetolactate synthase 2 catalytic subunit 0.37 MCAODC_00190 proA glutamate-5-semialdehyde dehydrogenase
Escherichia coli ECRC101 0.43 OKFHMN_14655 ilvG acetolactate synthase 2 catalytic subunit 0.37 OKFHMN_09670 proA glutamate-5-semialdehyde dehydrogenase
Escherichia coli ECRC99 0.43 KEDOAH_13495 ilvG acetolactate synthase 2 catalytic subunit 0.37 KEDOAH_18485 proA glutamate-5-semialdehyde dehydrogenase
Escherichia coli ECRC102 0.43 NIAGMN_12410 ilvG acetolactate synthase 2 catalytic subunit 0.37 NIAGMN_07530 proA glutamate-5-semialdehyde dehydrogenase
Escherichia coli ECRC98 0.43 JDDGAC_18275 ilvG acetolactate synthase 2 catalytic subunit 0.37 JDDGAC_13295 proA glutamate-5-semialdehyde dehydrogenase
Enterobacter sp. TBS_079 0.43 MPMX20_04502 Acetolactate synthase isozyme 2 large subunit 0.39 MPMX20_00928 Gamma-glutamyl phosphate reductase 0.56 40
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.43 GFF2904 Acetolactate synthase large subunit (EC 2.2.1.6) 0.39 GFF4115 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) low > 78
Escherichia coli ECOR38 0.43 HEPCGN_13365 ilvG acetolactate synthase 2 catalytic subunit 0.37 HEPCGN_07775 proA glutamate-5-semialdehyde dehydrogenase low > 85
Escherichia coli ECOR27 0.43 NOLOHH_06790 ilvG acetolactate synthase 2 catalytic subunit 0.37 NOLOHH_02045 proA glutamate-5-semialdehyde dehydrogenase low > 57
Escherichia coli ECRC62 0.43 BNILDI_04735 ilvG acetolactate synthase 2 catalytic subunit 0.37 BNILDI_00240 proA glutamate-5-semialdehyde dehydrogenase
Escherichia fergusonii Becca 0.43 EFB2_04868 Acetolactate synthase isozyme 2 large subunit 0.36 EFB2_03777 Gamma-glutamyl phosphate reductase low > 86
Escherichia coli Nissle 1917 0.43 ECOLIN_RS21650 acetolactate synthase 2 catalytic subunit 0.37 ECOLIN_RS01830 glutamate-5-semialdehyde dehydrogenase low > 52
Desulfovibrio vulgaris Miyazaki F 0.43 DvMF_0153 acetolactate synthase, large subunit, biosynthetic type (RefSeq) 0.32 DvMF_0612 proA gamma-glutamyl phosphate reductase (RefSeq) 0.88 21
Klebsiella michiganensis M5al 0.43 BWI76_RS00960 acetolactate synthase 2 catalytic subunit 0.38 BWI76_RS05835 gamma-glutamyl-phosphate reductase 0.63 53
Escherichia coli HS(pFamp)R (ATCC 700891) 0.43 OHPLBJKB_04285 Acetolactate synthase isozyme 2 large subunit 0.37 OHPLBJKB_03397 Gamma-glutamyl phosphate reductase low > 73
Escherichia coli BL21 0.42 ECD_03646 acetolactate synthase II, valine insensitive, large subunit 0.38 ECD_00240 gamma-glutamylphosphate reductase low > 60
Dickeya dadantii 3937 0.42 DDA3937_RS20170 acetolactate synthase 2 catalytic subunit 0.37 DDA3937_RS16530 glutamate-5-semialdehyde dehydrogenase low > 74
Dickeya dianthicola 67-19 0.42 HGI48_RS20310 acetolactate synthase 2 catalytic subunit 0.36 HGI48_RS16600 glutamate-5-semialdehyde dehydrogenase low > 71
Dickeya dianthicola ME23 0.41 DZA65_RS21350 acetolactate synthase 2 catalytic subunit 0.36 DZA65_RS17690 glutamate-5-semialdehyde dehydrogenase low > 75
Rahnella sp. WP5 0.41 EX31_RS14990 acetolactate synthase 2 catalytic subunit 0.37 EX31_RS20975 glutamate-5-semialdehyde dehydrogenase 0.76 62
Lysobacter sp. OAE881 0.41 ABIE51_RS17550 acetolactate synthase 2 catalytic subunit 0.30 ABIE51_RS13365 glutamate-5-semialdehyde dehydrogenase 0.89 52
Erwinia tracheiphila SCR3 0.41 LU632_RS24415 ilvG acetolactate synthase 2 catalytic subunit 0.36 LU632_RS01190 proA glutamate-5-semialdehyde dehydrogenase 0.61 39
Pantoea sp. MT58 0.41 IAI47_01020 acetolactate synthase 2 catalytic subunit 0.37 IAI47_15115 glutamate-5-semialdehyde dehydrogenase 0.61 62
Pectobacterium carotovorum WPP14 0.40 HER17_RS01060 acetolactate synthase 2 catalytic subunit 0.35 HER17_RS04705 glutamate-5-semialdehyde dehydrogenase low > 75
Synechococcus elongatus PCC 7942 0.40 Synpcc7942_0139 ilvB acetolactate synthase 3 catalytic subunit 0.29 Synpcc7942_2265 proA glutamate-5-semialdehyde dehydrogenase
Serratia liquefaciens MT49 0.40 IAI46_24360 acetolactate synthase 2 catalytic subunit 0.37 IAI46_04435 glutamate-5-semialdehyde dehydrogenase low > 86
Shewanella loihica PV-4 0.40 Shew_0289 acetolactate synthase 2 catalytic subunit (RefSeq) 0.35 Shew_2847 proA gamma-glutamyl phosphate reductase (RefSeq) low > 60
Shewanella sp. ANA-3 0.39 Shewana3_0356 acetolactate synthase 2 catalytic subunit (RefSeq) 0.34 Shewana3_0955 proA gamma-glutamyl phosphate reductase (RefSeq) 0.84 28
Shewanella oneidensis MR-1 0.39 SO4347 ilvG acetolactate synthase II, large subunit (NCBI ptt file) 0.34 SO1122 proA gamma-glutamyl phosphate reductase (NCBI ptt file) 0.90 14
Magnetospirillum magneticum AMB-1 0.39 AMB_RS17740 acetolactate synthase 3 large subunit 0.34 AMB_RS20640 glutamate-5-semialdehyde dehydrogenase
Xanthomonas campestris pv. campestris strain 8004 0.39 Xcc-8004.1059.1 Acetolactate synthase large subunit (EC 2.2.1.6) 0.31 Xcc-8004.2327.1 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.81 28
Vibrio cholerae E7946 ATCC 55056 0.39 CSW01_12565 acetolactate synthase 3 large subunit 0.37 CSW01_11570 glutamate-5-semialdehyde dehydrogenase low > 62
Shewanella amazonensis SB2B 0.39 Sama_3281 acetolactate synthase 2 catalytic subunit (RefSeq) 0.34 Sama_2515 proA gamma-glutamyl phosphate reductase (RefSeq) 0.81 36
Brevundimonas sp. GW460-12-10-14-LB2 0.39 A4249_RS10020 acetolactate synthase 2 catalytic subunit 0.26 A4249_RS16120 glutamate-5-semialdehyde dehydrogenase 0.99 31
Paraburkholderia bryophila 376MFSha3.1 0.39 H281DRAFT_04551 acetolactate synthase, large subunit 0.32 H281DRAFT_06324 glutamate-5-semialdehyde dehydrogenase
Alteromonas macleodii MIT1002 0.38 MIT1002_00503 Acetolactate synthase isozyme 3 large subunit 0.38 MIT1002_01885 Gamma-glutamyl phosphate reductase 0.97 21
Castellaniella sp019104865 MT123 0.38 ABCV34_RS01210 acetolactate synthase 3 catalytic subunit 0.34 ABCV34_RS00845 glutamate-5-semialdehyde dehydrogenase
Ralstonia solanacearum GMI1000 0.38 RS_RS10420 acetolactate synthase 3 large subunit 0.31 RS_RS13715 gamma-glutamyl-phosphate reductase
Burkholderia phytofirmans PsJN 0.38 BPHYT_RS06545 acetolactate synthase 0.32 BPHYT_RS16770 gamma-glutamyl phosphate reductase
Cupriavidus basilensis FW507-4G11 0.38 RR42_RS05435 acetolactate synthase 3 catalytic subunit 0.30 RR42_RS17530 gamma-glutamyl phosphate reductase
Ralstonia solanacearum UW163 0.38 UW163_RS10675 acetolactate synthase 3 large subunit 0.31 UW163_RS07800 glutamate-5-semialdehyde dehydrogenase
Ralstonia solanacearum IBSBF1503 0.38 RALBFv3_RS03050 acetolactate synthase 3 large subunit 0.31 RALBFv3_RS05825 glutamate-5-semialdehyde dehydrogenase
Caulobacter crescentus NA1000 Δfur 0.38 CCNA_02185 acetolactate synthase large subunit 0.29 CCNA_03543 gamma-glutamyl phosphate reductase low > 67
Caulobacter crescentus NA1000 0.38 CCNA_02185 acetolactate synthase large subunit 0.29 CCNA_03543 gamma-glutamyl phosphate reductase 0.89 41
Ralstonia solanacearum PSI07 0.38 RPSI07_RS14255 acetolactate synthase, large subunit, biosynthetic type 0.31 RPSI07_RS11475 glutamate-5-semialdehyde dehydrogenase
Ralstonia sp. UNC404CL21Col 0.38 ABZR87_RS14955 acetolactate synthase 3 catalytic subunit 0.31 ABZR87_RS01395 glutamate-5-semialdehyde dehydrogenase low > 80
Escherichia coli BW25113 0.38 b0077 ilvI acetolactate synthase III large subunit (NCBI) 0.37 b0243 proA gamma-glutamyl phosphate reductase (NCBI) 0.74 19
Pseudomonas stutzeri RCH2 0.38 Psest_1036 acetolactate synthase, large subunit, biosynthetic type 0.32 Psest_0508 gamma-glutamyl phosphate reductase
Azospirillum sp. SherDot2 0.38 MPMX19_01776 Acetolactate synthase isozyme 3 large subunit 0.35 MPMX19_01943 Gamma-glutamyl phosphate reductase
Variovorax sp. SCN45 0.38 GFF1597 Acetolactate synthase large subunit (EC 2.2.1.6) 0.30 GFF6326 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) low > 127
Paraburkholderia graminis OAS925 0.37 ABIE53_001574 acetolactate synthase-1/2/3 large subunit 0.32 ABIE53_003523 glutamate-5-semialdehyde dehydrogenase
Rhodospirillum rubrum S1H 0.37 Rru_A0467 Acetolactate synthase, large subunit, biosynthetic type (NCBI) 0.33 Rru_A1238 Gamma-glutamyl phosphate reductase GPR (NCBI)
Dechlorosoma suillum PS 0.37 Dsui_1925 acetolactate synthase, large subunit, biosynthetic type 0.31 Dsui_1220 gamma-glutamyl phosphate reductase
Variovorax sp. OAS795 0.37 ABID97_RS12545 biosynthetic-type acetolactate synthase large subunit 0.29 ABID97_RS04600 glutamate-5-semialdehyde dehydrogenase
Sphingomonas koreensis DSMZ 15582 0.37 Ga0059261_0068 acetolactate synthase, large subunit (EC 2.2.1.6) 0.32 Ga0059261_2506 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) 0.97 32
Bosea sp. OAE506 0.37 ABIE41_RS12890 acetolactate synthase 3 large subunit 0.28 ABIE41_RS07580 glutamate-5-semialdehyde dehydrogenase
Pseudomonas sp. S08-1 0.37 OH686_08130 acetolactate synthase, large subunit, biosynthetic type 0.32 OH686_09340 Gamma-glutamyl phosphate reductase 0.70 37
Pseudomonas syringae pv. syringae B728a 0.37 Psyr_0846 acetolactate synthase, large subunit 0.34 Psyr_4369 glutamate-5-semialdehyde dehydrogenase 0.91 13
Azospirillum brasilense Sp245 0.37 AZOBR_RS06560 acetolactate synthase 0.33 AZOBR_RS04075 gamma-glutamyl phosphate reductase
Pseudomonas syringae pv. syringae B728a ΔmexB 0.37 Psyr_0846 acetolactate synthase, large subunit 0.34 Psyr_4369 glutamate-5-semialdehyde dehydrogenase 0.89 7
Rhodopseudomonas palustris CGA009 0.37 TX73_010465 acetolactate synthase 3 large subunit 0.30 TX73_000855 glutamate-5-semialdehyde dehydrogenase
Mycobacterium tuberculosis H37Rv 0.37 Rv3003c Acetolactate synthase (large subunit) IlvB1 (acetohydroxy-acid synthase) 0.36 Rv2427c Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialdehyde dehydrogenase)
Rhizobium sp. OAE497 0.37 ABIE40_RS11495 acetolactate synthase 3 large subunit 0.35 ABIE40_RS18925 glutamate-5-semialdehyde dehydrogenase 0.87 47
Dinoroseobacter shibae DFL-12 0.37 Dshi_1779 acetolactate synthase, large subunit, biosynthetic type (RefSeq) 0.33 Dshi_1469 gamma-glutamyl phosphate reductase (RefSeq)
Hydrogenophaga sp. GW460-11-11-14-LB1 0.37 GFF4276 Acetolactate synthase large subunit (EC 2.2.1.6) 0.31 GFF2641 Gamma-glutamyl phosphate reductase (EC 1.2.1.41)
Paraburkholderia sabiae LMG 24235 0.37 QEN71_RS24225 acetolactate synthase 3 catalytic subunit 0.34 QEN71_RS26940 glutamate-5-semialdehyde dehydrogenase low > 153
Marinobacter adhaerens HP15 0.37 HP15_531 acetolactate synthase, large subunit, biosynthetic type 0.33 HP15_601 gamma-glutamyl phosphate reductase
Pseudomonas fluorescens SBW25 0.37 PFLU_RS25650 acetolactate synthase 3 large subunit 0.32 PFLU_RS26675 glutamate-5-semialdehyde dehydrogenase
Pseudomonas putida KT2440 0.37 PP_4680 acetohydroxybutanoate synthase / acetolactate synthase 0.33 PP_4811 Gamma-glutamyl phosphate reductase low > 96
Pseudomonas fluorescens SBW25-INTG 0.37 PFLU_RS25650 acetolactate synthase 3 large subunit 0.32 PFLU_RS26675 glutamate-5-semialdehyde dehydrogenase
Sinorhizobium meliloti 1021 0.37 SMc01431 acetolactate synthase 3 catalytic subunit 0.32 SMc03777 gamma-glutamyl phosphate reductase 0.93 30
Pseudomonas sp. RS175 0.36 PFR28_03699 Acetolactate synthase isozyme 3 large subunit 0.33 PFR28_03872 Gamma-glutamyl phosphate reductase
Pseudomonas fluorescens FW300-N2C3 0.36 AO356_16170 acetolactate synthase 3 catalytic subunit 0.33 AO356_15290 gamma-glutamyl phosphate reductase low > 104
Pseudomonas fluorescens FW300-N2E3 0.36 AO353_14495 acetolactate synthase 3 catalytic subunit 0.33 AO353_06495 gamma-glutamyl phosphate reductase 0.75 41
Pseudomonas simiae WCS417 0.36 PS417_23810 acetolactate synthase 3 catalytic subunit 0.32 PS417_24745 gamma-glutamyl phosphate reductase 0.69 41
Pseudomonas fluorescens FW300-N2E2 0.36 Pf6N2E2_5175 Acetolactate synthase large subunit (EC 2.2.1.6) 0.33 Pf6N2E2_4993 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) low > 103
Agrobacterium fabrum C58 0.36 Atu2036 acetolactate synthase III, large subunit 0.34 Atu2779 gamma-glutamyl phosphate reductase
Herbaspirillum seropedicae SmR1 0.36 HSERO_RS08650 acetolactate synthase 0.34 HSERO_RS02965 gamma-glutamyl phosphate reductase low > 78
Acinetobacter radioresistens SK82 0.36 MPMX26_00472 Acetolactate synthase isozyme 3 large subunit 0.35 MPMX26_00417 Gamma-glutamyl phosphate reductase low > 36
Pseudomonas fluorescens FW300-N1B4 0.36 Pf1N1B4_2878 Acetolactate synthase large subunit (EC 2.2.1.6) 0.33 Pf1N1B4_2688 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) low > 87
Pseudomonas fluorescens GW456-L13 0.36 PfGW456L13_1538 Acetolactate synthase large subunit (EC 2.2.1.6) 0.33 PfGW456L13_1356 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) low > 87
Acidovorax sp. GW101-3H11 0.35 Ac3H11_525 Acetolactate synthase large subunit (EC 2.2.1.6) 0.31 Ac3H11_704 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) low > 79
Phaeobacter inhibens DSM 17395 0.35 PGA1_c20210 acetolactate synthase isozyme 3 large subunit 0.33 PGA1_c15520 gamma-glutamyl phosphate reductase ProA 0.81 30
Bifidobacterium breve UCC2003 0.35 BBR_RS12350 acetolactate synthase large subunit 0.39 BBR_RS14075 glutamate-5-semialdehyde dehydrogenase low > 34
Dyella japonica UNC79MFTsu3.2 0.31 ABZR86_RS15935 biosynthetic-type acetolactate synthase large subunit 0.34 ABZR86_RS08680 glutamate-5-semialdehyde dehydrogenase low > 74
Rhodanobacter denitrificans MT42 0.29 LRK55_RS09950 biosynthetic-type acetolactate synthase large subunit 0.33 LRK55_RS02125 glutamate-5-semialdehyde dehydrogenase low > 63
Rhodanobacter denitrificans FW104-10B01 0.29 LRK54_RS10310 biosynthetic-type acetolactate synthase large subunit 0.33 LRK54_RS02370 glutamate-5-semialdehyde dehydrogenase 0.86 9
Rhodanobacter sp. FW510-T8 0.28 OKGIIK_13610 ilvB biosynthetic-type acetolactate synthase large subunit 0.30 OKGIIK_09415 proA glutamate-5-semialdehyde dehydrogenase low > 52

Not shown: 2 genomes with orthologs for BT2077 only; 1 genomes with orthologs for BT3718 only