Conservation of cofitness between BT3718 and BT2078 in Bacteroides thetaiotaomicron VPI-5482

99 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bacteroides thetaiotaomicron VPI-5482 1.0 BT3718 gamma-glutamyl phosphate reductase (NCBI ptt file) 1.0 BT2078 dihydroxy-acid dehydratase (NCBI ptt file) 0.95 8
Bacteroides ovatus ATCC 8483 0.90 BACOVA_03534 glutamate-5-semialdehyde dehydrogenase 0.94 BACOVA_03302 dihydroxy-acid dehydratase 0.96 13
Bacteroides stercoris CC31F 0.73 HMPREF1181_RS03320 glutamate-5-semialdehyde dehydrogenase 0.91 HMPREF1181_RS08335 dihydroxy-acid dehydratase 0.88 36
Parabacteroides merdae CL09T00C40 0.68 HMPREF1078_RS10655 glutamate-5-semialdehyde dehydrogenase 0.83 HMPREF1078_RS16695 dihydroxy-acid dehydratase low > 61
Pontibacter actiniarum KMM 6156, DSM 19842 0.64 CA264_07720 gamma-glutamyl-phosphate reductase 0.27 CA264_06935 dihydroxy-acid dehydratase low > 74
Phocaeicola dorei CL03T12C01 0.62 ABI39_RS02875 glutamate-5-semialdehyde dehydrogenase 0.88 ABI39_RS12715 dihydroxy-acid dehydratase 0.87 12
Phocaeicola vulgatus CL09T03C04 0.61 HMPREF1058_RS08645 glutamate-5-semialdehyde dehydrogenase 0.89 HMPREF1058_RS16815 dihydroxy-acid dehydratase 0.88 25
Mucilaginibacter yixingensis YX-36 DSM 26809 0.60 ABZR88_RS22165 glutamate-5-semialdehyde dehydrogenase 0.28 ABZR88_RS11575 dihydroxy-acid dehydratase 0.84 7
Pedobacter sp. GW460-11-11-14-LB5 0.58 CA265_RS20850 glutamate-5-semialdehyde dehydrogenase 0.26 CA265_RS15795 dihydroxy-acid dehydratase 0.93 21
Bifidobacterium breve UCC2003 0.39 BBR_RS14075 glutamate-5-semialdehyde dehydrogenase 0.56 BBR_RS17635 dihydroxy-acid dehydratase low > 34
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.39 GFF4115 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.64 GFF2901 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 78
Enterobacter sp. TBS_079 0.39 MPMX20_00928 Gamma-glutamyl phosphate reductase 0.65 MPMX20_04499 Dihydroxy-acid dehydratase 0.95 2
Enterobacter asburiae PDN3 0.38 EX28DRAFT_2650 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) 0.64 EX28DRAFT_4443 dihydroxy-acid dehydratase 0.75 41
Alteromonas macleodii MIT1002 0.38 MIT1002_01885 Gamma-glutamyl phosphate reductase 0.63 MIT1002_04041 Dihydroxy-acid dehydratase 0.97 21
Escherichia coli BL21 0.38 ECD_00240 gamma-glutamylphosphate reductase 0.64 ECD_03649 dihydroxyacid dehydratase low > 60
Klebsiella michiganensis M5al 0.38 BWI76_RS05835 gamma-glutamyl-phosphate reductase 0.64 BWI76_RS00975 dihydroxy-acid dehydratase 0.84 8
Escherichia coli ECRC101 0.37 OKFHMN_09670 proA glutamate-5-semialdehyde dehydrogenase 0.64 OKFHMN_14640 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC101 0.37 MCAODC_00190 proA glutamate-5-semialdehyde dehydrogenase 0.64 MCAODC_05145 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC102 0.37 NIAGMN_07530 proA glutamate-5-semialdehyde dehydrogenase 0.64 NIAGMN_12395 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC99 0.37 KEDOAH_18485 proA glutamate-5-semialdehyde dehydrogenase 0.64 KEDOAH_13510 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC98 0.37 JDDGAC_13295 proA glutamate-5-semialdehyde dehydrogenase 0.64 JDDGAC_18260 ilvD dihydroxy-acid dehydratase — —
Vibrio cholerae E7946 ATCC 55056 0.37 CSW01_11570 glutamate-5-semialdehyde dehydrogenase 0.62 CSW01_00140 dihydroxy-acid dehydratase low > 62
Escherichia coli ECOR38 0.37 HEPCGN_07775 proA glutamate-5-semialdehyde dehydrogenase 0.64 HEPCGN_13350 ilvD dihydroxy-acid dehydratase low > 85
Rahnella sp. WP5 0.37 EX31_RS20975 glutamate-5-semialdehyde dehydrogenase 0.60 EX31_RS15005 dihydroxy-acid dehydratase 0.99 2
Serratia liquefaciens MT49 0.37 IAI46_04435 glutamate-5-semialdehyde dehydrogenase 0.62 IAI46_24345 dihydroxy-acid dehydratase 0.71 35
Escherichia coli BW25113 0.37 b0243 proA gamma-glutamyl phosphate reductase (NCBI) 0.64 b3771 ilvD dihydroxy-acid dehydratase (NCBI) 0.95 3
Escherichia coli ECOR27 0.37 NOLOHH_02045 proA glutamate-5-semialdehyde dehydrogenase 0.64 NOLOHH_06775 ilvD dihydroxy-acid dehydratase low > 57
Escherichia coli HS(pFamp)R (ATCC 700891) 0.37 OHPLBJKB_03397 Gamma-glutamyl phosphate reductase 0.64 OHPLBJKB_04282 Dihydroxy-acid dehydratase low > 73
Pantoea sp. MT58 0.37 IAI47_15115 glutamate-5-semialdehyde dehydrogenase 0.62 IAI47_01035 dihydroxy-acid dehydratase 0.94 9
Escherichia coli ECRC62 0.37 BNILDI_00240 proA glutamate-5-semialdehyde dehydrogenase 0.64 BNILDI_04750 ilvD dihydroxy-acid dehydratase — —
Dickeya dadantii 3937 0.37 DDA3937_RS16530 glutamate-5-semialdehyde dehydrogenase 0.62 DDA3937_RS20155 dihydroxy-acid dehydratase 0.87 5
Escherichia coli Nissle 1917 0.37 ECOLIN_RS01830 glutamate-5-semialdehyde dehydrogenase 0.65 ECOLIN_RS21665 dihydroxy-acid dehydratase 0.48 13
Dickeya dianthicola ME23 0.36 DZA65_RS17690 glutamate-5-semialdehyde dehydrogenase 0.62 DZA65_RS21335 dihydroxy-acid dehydratase 0.60 43
Erwinia tracheiphila SCR3 0.36 LU632_RS01190 proA glutamate-5-semialdehyde dehydrogenase 0.62 LU632_RS24400 ilvD dihydroxy-acid dehydratase 0.74 30
Escherichia fergusonii Becca 0.36 EFB2_03777 Gamma-glutamyl phosphate reductase 0.65 EFB2_04865 Dihydroxy-acid dehydratase low > 86
Mycobacterium tuberculosis H37Rv 0.36 Rv2427c Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialdehyde dehydrogenase) 0.29 Rv0189c Probable dihydroxy-acid dehydratase IlvD (dad) — —
Dickeya dianthicola 67-19 0.36 HGI48_RS16600 glutamate-5-semialdehyde dehydrogenase 0.63 HGI48_RS20295 dihydroxy-acid dehydratase 0.82 18
Shewanella loihica PV-4 0.35 Shew_2847 proA gamma-glutamyl phosphate reductase (RefSeq) 0.61 Shew_0292 dihydroxy-acid dehydratase (RefSeq) 0.97 17
Acinetobacter radioresistens SK82 0.35 MPMX26_00417 Gamma-glutamyl phosphate reductase 0.28 MPMX26_03019 Dihydroxy-acid dehydratase 0.71 35
Pectobacterium carotovorum WPP14 0.35 HER17_RS04705 glutamate-5-semialdehyde dehydrogenase 0.62 HER17_RS01075 dihydroxy-acid dehydratase 0.97 5
Azospirillum sp. SherDot2 0.35 MPMX19_01943 Gamma-glutamyl phosphate reductase 0.61 MPMX19_05356 Dihydroxy-acid dehydratase — —
Rhizobium sp. OAE497 0.35 ABIE40_RS18925 glutamate-5-semialdehyde dehydrogenase 0.64 ABIE40_RS08005 dihydroxy-acid dehydratase 0.84 70
Castellaniella sp019104865 MT123 0.34 ABCV34_RS00845 glutamate-5-semialdehyde dehydrogenase 0.62 ABCV34_RS14810 dihydroxy-acid dehydratase — —
Paraburkholderia sabiae LMG 24235 0.34 QEN71_RS26940 glutamate-5-semialdehyde dehydrogenase 0.63 QEN71_RS21095 dihydroxy-acid dehydratase low > 153
Shewanella sp. ANA-3 0.34 Shewana3_0955 proA gamma-glutamyl phosphate reductase (RefSeq) 0.61 Shewana3_0358 dihydroxy-acid dehydratase (RefSeq) 0.97 4
Herbaspirillum seropedicae SmR1 0.34 HSERO_RS02965 gamma-glutamyl phosphate reductase 0.63 HSERO_RS02650 dihydroxy-acid dehydratase low > 78
Shewanella amazonensis SB2B 0.34 Sama_2515 proA gamma-glutamyl phosphate reductase (RefSeq) 0.61 Sama_3279 dihydroxy-acid dehydratase (RefSeq) 0.97 3
Shewanella oneidensis MR-1 0.34 SO1122 proA gamma-glutamyl phosphate reductase (NCBI ptt file) 0.61 SO4345 ilvD dihydroxy-acid dehydratase (NCBI ptt file) 0.99 5
Dyella japonica UNC79MFTsu3.2 0.34 ABZR86_RS08680 glutamate-5-semialdehyde dehydrogenase 0.26 ABZR86_RS15945 dihydroxy-acid dehydratase 0.84 52
Magnetospirillum magneticum AMB-1 0.34 AMB_RS20640 glutamate-5-semialdehyde dehydrogenase 0.62 AMB_RS12770 dihydroxy-acid dehydratase — —
Agrobacterium fabrum C58 0.34 Atu2779 gamma-glutamyl phosphate reductase 0.64 Atu1918 dihydroxy-acid dehydratase — —
Pseudomonas syringae pv. syringae B728a 0.34 Psyr_4369 glutamate-5-semialdehyde dehydrogenase 0.62 Psyr_0469 dihydroxyacid dehydratase 0.92 4
Pseudomonas syringae pv. syringae B728a ΔmexB 0.34 Psyr_4369 glutamate-5-semialdehyde dehydrogenase 0.62 Psyr_0469 dihydroxyacid dehydratase 0.94 4
Pseudomonas fluorescens FW300-N1B4 0.33 Pf1N1B4_2688 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.63 Pf1N1B4_2303 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 87
Rhodanobacter denitrificans FW104-10B01 0.33 LRK54_RS02370 glutamate-5-semialdehyde dehydrogenase 0.25 LRK54_RS10320 dihydroxy-acid dehydratase 0.86 13
Rhodanobacter denitrificans MT42 0.33 LRK55_RS02125 glutamate-5-semialdehyde dehydrogenase 0.25 LRK55_RS09960 dihydroxy-acid dehydratase low > 63
Marinobacter adhaerens HP15 0.33 HP15_601 gamma-glutamyl phosphate reductase 0.61 HP15_595 dihydroxy-acid dehydratase — —
Rhodospirillum rubrum S1H 0.33 Rru_A1238 Gamma-glutamyl phosphate reductase GPR (NCBI) 0.59 Rru_A1786 Dihydroxy-acid dehydratase (NCBI) — —
Pseudomonas sp. RS175 0.33 PFR28_03872 Gamma-glutamyl phosphate reductase 0.63 PFR28_04278 Dihydroxy-acid dehydratase — —
Pseudomonas fluorescens GW456-L13 0.33 PfGW456L13_1356 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.63 PfGW456L13_973 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.44 15
Phaeobacter inhibens DSM 17395 0.33 PGA1_c15520 gamma-glutamyl phosphate reductase ProA 0.61 PGA1_c29490 dihydroxy-acid dehydratase LivD 0.79 22
Dinoroseobacter shibae DFL-12 0.33 Dshi_1469 gamma-glutamyl phosphate reductase (RefSeq) 0.31 Dshi_0129 dihydroxy-acid dehydratase (RefSeq) — —
Pseudomonas fluorescens FW300-N2C3 0.33 AO356_15290 gamma-glutamyl phosphate reductase 0.63 AO356_13250 dihydroxy-acid dehydratase low > 104
Pseudomonas putida KT2440 0.33 PP_4811 Gamma-glutamyl phosphate reductase 0.63 PP_5128 Dihydroxy-acid dehydratase low > 96
Pseudomonas fluorescens FW300-N2E3 0.33 AO353_06495 gamma-glutamyl phosphate reductase 0.63 AO353_08345 dihydroxy-acid dehydratase 0.67 18
Pseudomonas fluorescens FW300-N2E2 0.33 Pf6N2E2_4993 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.63 Pf6N2E2_4564 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 103
Azospirillum brasilense Sp245 0.33 AZOBR_RS04075 gamma-glutamyl phosphate reductase 0.62 AZOBR_RS15015 dihydroxy-acid dehydratase — —
Sinorhizobium meliloti 1021 0.32 SMc03777 gamma-glutamyl phosphate reductase 0.65 SMc04045 dihydroxy-acid dehydratase 0.93 4
Paraburkholderia bryophila 376MFSha3.1 0.32 H281DRAFT_06324 glutamate-5-semialdehyde dehydrogenase 0.63 H281DRAFT_05312 dihydroxyacid dehydratase low > 103
Paraburkholderia graminis OAS925 0.32 ABIE53_003523 glutamate-5-semialdehyde dehydrogenase 0.62 ABIE53_006513 dihydroxy-acid dehydratase low > 113
Burkholderia phytofirmans PsJN 0.32 BPHYT_RS16770 gamma-glutamyl phosphate reductase 0.63 BPHYT_RS10100 dihydroxy-acid dehydratase — —
Desulfovibrio vulgaris Miyazaki F 0.32 DvMF_0612 proA gamma-glutamyl phosphate reductase (RefSeq) 0.39 DvMF_2034 dihydroxy-acid dehydratase (RefSeq) 0.85 28
Pseudomonas sp. S08-1 0.32 OH686_09340 Gamma-glutamyl phosphate reductase 0.64 OH686_14100 dihydroxy-acid dehydratase 0.70 37
Sphingomonas koreensis DSMZ 15582 0.32 Ga0059261_2506 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) 0.28 Ga0059261_4216 Dihydroxyacid dehydratase/phosphogluconate dehydratase 0.98 3
Pseudomonas fluorescens SBW25 0.32 PFLU_RS26675 glutamate-5-semialdehyde dehydrogenase 0.63 PFLU_RS28535 dihydroxy-acid dehydratase — —
Desulfovibrio vulgaris Hildenborough JW710 0.32 DVU1953 proA gamma-glutamyl phosphate reductase (TIGR) 0.40 DVU3373 ilvD dihydroxy-acid dehydratase (TIGR) 0.85 16
Pseudomonas stutzeri RCH2 0.32 Psest_0508 gamma-glutamyl phosphate reductase 0.64 Psest_0234 dihydroxy-acid dehydratase — —
Pseudomonas fluorescens SBW25-INTG 0.32 PFLU_RS26675 glutamate-5-semialdehyde dehydrogenase 0.63 PFLU_RS28535 dihydroxy-acid dehydratase — —
Pseudomonas simiae WCS417 0.32 PS417_24745 gamma-glutamyl phosphate reductase 0.63 PS417_26890 dihydroxy-acid dehydratase 0.64 16
Dechlorosoma suillum PS 0.31 Dsui_1220 gamma-glutamyl phosphate reductase 0.66 Dsui_1122 dihydroxy-acid dehydratase — —
Ralstonia sp. UNC404CL21Col 0.31 ABZR87_RS01395 glutamate-5-semialdehyde dehydrogenase 0.63 ABZR87_RS00240 dihydroxy-acid dehydratase low > 80
Ralstonia solanacearum UW163 0.31 UW163_RS07800 glutamate-5-semialdehyde dehydrogenase 0.29 UW163_RS09135 dihydroxy-acid dehydratase — —
Ralstonia solanacearum IBSBF1503 0.31 RALBFv3_RS05825 glutamate-5-semialdehyde dehydrogenase 0.29 RALBFv3_RS04535 dihydroxy-acid dehydratase — —
Ralstonia solanacearum PSI07 0.31 RPSI07_RS11475 glutamate-5-semialdehyde dehydrogenase 0.30 RPSI07_RS12840 dihydroxy-acid dehydratase — —
Acidovorax sp. GW101-3H11 0.31 Ac3H11_704 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.62 Ac3H11_955 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 79
Ralstonia solanacearum GMI1000 0.31 RS_RS13715 gamma-glutamyl-phosphate reductase 0.29 RS_RS12105 dihydroxy-acid dehydratase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.31 GFF2641 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.55 GFF2073 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 90
Xanthomonas campestris pv. campestris strain 8004 0.31 Xcc-8004.2327.1 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.63 Xcc-8004.451.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.73 41
Cupriavidus basilensis FW507-4G11 0.30 RR42_RS17530 gamma-glutamyl phosphate reductase 0.30 RR42_RS16210 dihydroxy-acid dehydratase — —
Lysobacter sp. OAE881 0.30 ABIE51_RS13365 glutamate-5-semialdehyde dehydrogenase 0.27 ABIE51_RS17540 dihydroxy-acid dehydratase 0.90 32
Rhodanobacter sp. FW510-T8 0.30 OKGIIK_09415 proA glutamate-5-semialdehyde dehydrogenase 0.26 OKGIIK_13600 ilvD dihydroxy-acid dehydratase low > 52
Variovorax sp. SCN45 0.30 GFF6326 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.29 GFF471 Dihydroxy-acid dehydratase (EC 4.2.1.9) — —
Rhodopseudomonas palustris CGA009 0.30 TX73_000855 glutamate-5-semialdehyde dehydrogenase 0.62 TX73_007515 dihydroxy-acid dehydratase — —
Caulobacter crescentus NA1000 Δfur 0.29 CCNA_03543 gamma-glutamyl phosphate reductase 0.62 CCNA_03139 dihydroxy-acid dehydratase low > 67
Caulobacter crescentus NA1000 0.29 CCNA_03543 gamma-glutamyl phosphate reductase 0.62 CCNA_03139 dihydroxy-acid dehydratase 0.92 7
Variovorax sp. OAS795 0.29 ABID97_RS04600 glutamate-5-semialdehyde dehydrogenase 0.29 ABID97_RS17500 dihydroxy-acid dehydratase — —
Synechococcus elongatus PCC 7942 0.29 Synpcc7942_2265 proA glutamate-5-semialdehyde dehydrogenase 0.65 Synpcc7942_0626 ilvD dihydroxy-acid dehydratase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.28 Echvi_2633 gamma-glutamylphosphate reductase (EC 1.2.1.41) (from data) 0.28 Echvi_2055 dihydroxy-acid dehydratase 0.88 15
Bosea sp. OAE506 0.28 ABIE41_RS07580 glutamate-5-semialdehyde dehydrogenase 0.29 ABIE41_RS15690 dihydroxy-acid dehydratase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.26 A4249_RS16120 glutamate-5-semialdehyde dehydrogenase 0.24 A4249_RS10030 dihydroxy-acid dehydratase 0.99 10

Not shown: 1 genomes with orthologs for BT3718 only; 2 genomes with orthologs for BT2078 only