Conservation of cofitness between b0386 and b3771 in Escherichia coli BW25113

99 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0386 proC pyrroline-5-carboxylate reductase (NCBI) 1.0 b3771 ilvD dihydroxy-acid dehydratase (NCBI) 0.87 6
Escherichia coli ECOR38 1.00 HEPCGN_07250 proC pyrroline-5-carboxylate reductase 1.00 HEPCGN_13350 ilvD dihydroxy-acid dehydratase low > 85
Escherichia coli Nissle 1917 1.00 ECOLIN_RS02345 pyrroline-5-carboxylate reductase 0.99 ECOLIN_RS21665 dihydroxy-acid dehydratase low > 52
Escherichia coli BL21 1.00 ECD_00333 pyrroline-5-carboxylate reductase, NAD(P)-binding 1.00 ECD_03649 dihydroxyacid dehydratase low > 60
Escherichia coli ECOR27 1.00 NOLOHH_01535 proC pyrroline-5-carboxylate reductase 1.00 NOLOHH_06775 ilvD dihydroxy-acid dehydratase low > 57
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03288 Pyrroline-5-carboxylate reductase 1.00 OHPLBJKB_04282 Dihydroxy-acid dehydratase low > 73
Escherichia coli ECRC62 1.00 BNILDI_22950 proC pyrroline-5-carboxylate reductase 1.00 BNILDI_04750 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC101 1.00 OKFHMN_08610 proC pyrroline-5-carboxylate reductase 1.00 OKFHMN_14640 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC99 1.00 KEDOAH_19355 proC pyrroline-5-carboxylate reductase 1.00 KEDOAH_13510 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC102 1.00 NIAGMN_06665 proC pyrroline-5-carboxylate reductase 1.00 NIAGMN_12395 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC98 1.00 JDDGAC_12265 proC pyrroline-5-carboxylate reductase 1.00 JDDGAC_18260 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC101 1.00 MCAODC_27835 proC pyrroline-5-carboxylate reductase 1.00 MCAODC_05145 ilvD dihydroxy-acid dehydratase — —
Escherichia fergusonii Becca 0.99 EFB2_03670 Pyrroline-5-carboxylate reductase 0.99 EFB2_04865 Dihydroxy-acid dehydratase low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF4283 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.97 GFF2901 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 78
Klebsiella michiganensis M5al 0.94 BWI76_RS06170 pyrroline-5-carboxylate reductase 0.96 BWI76_RS00975 dihydroxy-acid dehydratase — —
Enterobacter asburiae PDN3 0.93 EX28DRAFT_2585 pyrroline-5-carboxylate reductase 0.96 EX28DRAFT_4443 dihydroxy-acid dehydratase low > 76
Enterobacter sp. TBS_079 0.93 MPMX20_00976 Pyrroline-5-carboxylate reductase 0.97 MPMX20_04499 Dihydroxy-acid dehydratase 0.92 3
Erwinia tracheiphila SCR3 0.71 LU632_RS18995 proC pyrroline-5-carboxylate reductase 0.86 LU632_RS24400 ilvD dihydroxy-acid dehydratase 0.62 20
Pantoea sp. MT58 0.64 IAI47_14945 pyrroline-5-carboxylate reductase 0.89 IAI47_01035 dihydroxy-acid dehydratase 0.85 10
Synechococcus elongatus PCC 7942 0.35 Synpcc7942_2058 proC pyrroline-5-carboxylate reductase 0.75 Synpcc7942_0626 ilvD dihydroxy-acid dehydratase — —
Lysobacter sp. OAE881 0.30 ABIE51_RS16065 pyrroline-5-carboxylate reductase 0.27 ABIE51_RS17540 dihydroxy-acid dehydratase 0.88 14
Shewanella loihica PV-4 0.29 Shew_1136 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.78 Shew_0292 dihydroxy-acid dehydratase (RefSeq) 0.94 26
Dyella japonica UNC79MFTsu3.2 0.29 ABZR86_RS10425 pyrroline-5-carboxylate reductase 0.28 ABZR86_RS15945 dihydroxy-acid dehydratase 0.84 67
Shewanella amazonensis SB2B 0.29 Sama_2478 pyrroline-5-carboxylate reductase (RefSeq) 0.79 Sama_3279 dihydroxy-acid dehydratase (RefSeq) 0.97 3
Marinobacter adhaerens HP15 0.29 HP15_287 pyrroline-5-carboxylate reductase 0.70 HP15_595 dihydroxy-acid dehydratase low > 73
Pseudomonas sp. S08-1 0.28 OH686_10980 pyrroline-5-carboxylate reductase 0.75 OH686_14100 dihydroxy-acid dehydratase 0.65 31
Alteromonas macleodii MIT1002 0.28 MIT1002_03062 Pyrroline-5-carboxylate reductase 0.79 MIT1002_04041 Dihydroxy-acid dehydratase 0.96 16
Pectobacterium carotovorum WPP14 0.28 HER17_RS03805 pyrroline-5-carboxylate reductase 0.91 HER17_RS01075 dihydroxy-acid dehydratase — —
Pseudomonas stutzeri RCH2 0.28 Psest_0283 pyrroline-5-carboxylate reductase 0.75 Psest_0234 dihydroxy-acid dehydratase — —
Dechlorosoma suillum PS 0.28 Dsui_0602 pyrroline-5-carboxylate reductase 0.74 Dsui_1122 dihydroxy-acid dehydratase — —
Dickeya dadantii 3937 0.28 DDA3937_RS17305 pyrroline-5-carboxylate reductase 0.92 DDA3937_RS20155 dihydroxy-acid dehydratase 0.83 3
Shewanella oneidensis MR-1 0.28 SO3354 proC pyrroline-5-carboxylate reductase (NCBI ptt file) 0.80 SO4345 ilvD dihydroxy-acid dehydratase (NCBI ptt file) 0.98 5
Rhodanobacter denitrificans MT42 0.27 LRK55_RS04030 pyrroline-5-carboxylate reductase 0.26 LRK55_RS09960 dihydroxy-acid dehydratase — —
Rhodanobacter denitrificans FW104-10B01 0.27 LRK54_RS04260 pyrroline-5-carboxylate reductase 0.26 LRK54_RS10320 dihydroxy-acid dehydratase 0.81 12
Acidovorax sp. GW101-3H11 0.27 Ac3H11_788 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.74 Ac3H11_955 Dihydroxy-acid dehydratase (EC 4.2.1.9) — —
Rhodanobacter sp. FW510-T8 0.27 OKGIIK_11135 proC pyrroline-5-carboxylate reductase 0.27 OKGIIK_13600 ilvD dihydroxy-acid dehydratase low > 52
Shewanella sp. ANA-3 0.27 Shewana3_1193 pyrroline-5-carboxylate reductase (RefSeq) 0.80 Shewana3_0358 dihydroxy-acid dehydratase (RefSeq) 0.96 3
Vibrio cholerae E7946 ATCC 55056 0.27 CSW01_02450 pyrroline-5-carboxylate reductase 0.85 CSW01_00140 dihydroxy-acid dehydratase low > 62
Pseudomonas putida KT2440 0.27 PP_5095 pyrroline-5-carboxylate reductase 0.74 PP_5128 Dihydroxy-acid dehydratase 0.43 30
Paraburkholderia graminis OAS925 0.27 ABIE53_000840 pyrroline-5-carboxylate reductase 0.74 ABIE53_006513 dihydroxy-acid dehydratase low > 113
Burkholderia phytofirmans PsJN 0.27 BPHYT_RS03490 pyrroline-5-carboxylate reductase 0.74 BPHYT_RS10100 dihydroxy-acid dehydratase — —
Paraburkholderia bryophila 376MFSha3.1 0.27 H281DRAFT_04679 pyrroline-5-carboxylate reductase 0.74 H281DRAFT_05312 dihydroxyacid dehydratase low > 103
Pseudomonas simiae WCS417 0.27 PS417_26730 pyrroline-5-carboxylate reductase 0.75 PS417_26890 dihydroxy-acid dehydratase 0.54 30
Dickeya dianthicola 67-19 0.26 HGI48_RS17350 pyrroline-5-carboxylate reductase 0.91 HGI48_RS20295 dihydroxy-acid dehydratase — —
Serratia liquefaciens MT49 0.26 IAI46_21415 pyrroline-5-carboxylate reductase 0.90 IAI46_24345 dihydroxy-acid dehydratase low > 86
Dickeya dianthicola ME23 0.26 DZA65_RS18440 pyrroline-5-carboxylate reductase 0.91 DZA65_RS21335 dihydroxy-acid dehydratase — —
Ralstonia sp. UNC404CL21Col 0.26 ABZR87_RS01230 pyrroline-5-carboxylate reductase 0.75 ABZR87_RS00240 dihydroxy-acid dehydratase — —
Ralstonia solanacearum PSI07 0.26 RPSI07_RS11720 pyrroline-5-carboxylate reductase 0.29 RPSI07_RS12840 dihydroxy-acid dehydratase — —
Pseudomonas fluorescens SBW25 0.26 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.75 PFLU_RS28535 dihydroxy-acid dehydratase — —
Pseudomonas fluorescens SBW25-INTG 0.26 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.75 PFLU_RS28535 dihydroxy-acid dehydratase — —
Ralstonia solanacearum UW163 0.26 UW163_RS08045 pyrroline-5-carboxylate reductase 0.29 UW163_RS09135 dihydroxy-acid dehydratase — —
Ralstonia solanacearum IBSBF1503 0.26 RALBFv3_RS05580 pyrroline-5-carboxylate reductase 0.29 RALBFv3_RS04535 dihydroxy-acid dehydratase — —
Cupriavidus basilensis FW507-4G11 0.26 RR42_RS17360 pyrroline-5-carboxylate reductase 0.29 RR42_RS16210 dihydroxy-acid dehydratase — —
Desulfovibrio vulgaris Hildenborough JW710 0.26 DVU2332 proC pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.39 DVU3373 ilvD dihydroxy-acid dehydratase (TIGR) 0.84 17
Rahnella sp. WP5 0.26 EX31_RS02690 pyrroline-5-carboxylate reductase 0.87 EX31_RS15005 dihydroxy-acid dehydratase 0.97 8
Variovorax sp. SCN45 0.26 GFF5553 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.31 GFF471 Dihydroxy-acid dehydratase (EC 4.2.1.9) — —
Pseudomonas sp. RS175 0.26 PFR28_04243 Pyrroline-5-carboxylate reductase 0.75 PFR28_04278 Dihydroxy-acid dehydratase — —
Pseudomonas fluorescens FW300-N2E3 0.26 AO353_08165 pyrroline-5-carboxylate reductase 0.75 AO353_08345 dihydroxy-acid dehydratase 0.69 12
Paraburkholderia sabiae LMG 24235 0.26 QEN71_RS26600 pyrroline-5-carboxylate reductase 0.74 QEN71_RS21095 dihydroxy-acid dehydratase low > 153
Hydrogenophaga sp. GW460-11-11-14-LB1 0.25 GFF2806 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.64 GFF2073 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 90
Ralstonia solanacearum GMI1000 0.25 RS_RS13440 pyrroline-5-carboxylate reductase 0.28 RS_RS12105 dihydroxy-acid dehydratase — —
Herbaspirillum seropedicae SmR1 0.25 HSERO_RS18990 pyrroline-5-carboxylate reductase 0.74 HSERO_RS02650 dihydroxy-acid dehydratase 0.82 6
Bifidobacterium breve UCC2003 0.25 BBR_RS14625 pyrroline-5-carboxylate reductase 0.56 BBR_RS17635 dihydroxy-acid dehydratase low > 34
Pseudomonas syringae pv. syringae B728a 0.25 Psyr_0476 pyrroline-5-carboxylate reductase 0.74 Psyr_0469 dihydroxyacid dehydratase — —
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_2341 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.75 Pf1N1B4_2303 Dihydroxy-acid dehydratase (EC 4.2.1.9) — —
Pseudomonas fluorescens GW456-L13 0.25 PfGW456L13_1010 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.75 PfGW456L13_973 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.84 36
Pseudomonas syringae pv. syringae B728a ΔmexB 0.25 Psyr_0476 pyrroline-5-carboxylate reductase 0.74 Psyr_0469 dihydroxyacid dehydratase 0.89 1
Desulfovibrio vulgaris Miyazaki F 0.25 DvMF_3161 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.39 DvMF_2034 dihydroxy-acid dehydratase (RefSeq) 0.87 26
Phocaeicola dorei CL03T12C01 0.25 ABI39_RS02960 pyrroline-5-carboxylate reductase 0.64 ABI39_RS12715 dihydroxy-acid dehydratase 0.88 2
Phocaeicola vulgatus CL09T03C04 0.25 HMPREF1058_RS08830 pyrroline-5-carboxylate reductase 0.64 HMPREF1058_RS16815 dihydroxy-acid dehydratase 0.87 25
Xanthomonas campestris pv. campestris strain 8004 0.24 Xcc-8004.1710.1 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.72 Xcc-8004.451.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 74
Agrobacterium fabrum C58 0.24 Atu2209 pyrroline-5-carboxylate reductase 0.73 Atu1918 dihydroxy-acid dehydratase — —
Pseudomonas fluorescens FW300-N2E2 0.24 Pf6N2E2_4600 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.75 Pf6N2E2_4564 Dihydroxy-acid dehydratase (EC 4.2.1.9) — —
Variovorax sp. OAS795 0.24 ABID97_RS01555 pyrroline-5-carboxylate reductase 0.31 ABID97_RS17500 dihydroxy-acid dehydratase — —
Pseudomonas fluorescens FW300-N2C3 0.24 AO356_13420 pyrroline-5-carboxylate reductase 0.75 AO356_13250 dihydroxy-acid dehydratase — —
Phaeobacter inhibens DSM 17395 0.24 PGA1_c24700 pyrroline-5-carboxylate reductase ProC 0.70 PGA1_c29490 dihydroxy-acid dehydratase LivD 0.82 21
Rhizobium sp. OAE497 0.23 ABIE40_RS13005 pyrroline-5-carboxylate reductase 0.75 ABIE40_RS08005 dihydroxy-acid dehydratase 0.58 103
Castellaniella sp019104865 MT123 0.23 ABCV34_RS03610 pyrroline-5-carboxylate reductase 0.72 ABCV34_RS14810 dihydroxy-acid dehydratase low > 48
Sinorhizobium meliloti 1021 0.23 SMc02677 pyrroline-5-carboxylate reductase 0.75 SMc04045 dihydroxy-acid dehydratase 0.68 12
Bacteroides thetaiotaomicron VPI-5482 0.23 BT3757 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.63 BT2078 dihydroxy-acid dehydratase (NCBI ptt file) 0.92 5
Dinoroseobacter shibae DFL-12 0.23 Dshi_2645 pyrroline-5-carboxylate reductase (RefSeq) 0.31 Dshi_0129 dihydroxy-acid dehydratase (RefSeq) — —
Bacteroides stercoris CC31F 0.22 HMPREF1181_RS03440 pyrroline-5-carboxylate reductase 0.64 HMPREF1181_RS08335 dihydroxy-acid dehydratase 0.84 45
Mycobacterium tuberculosis H37Rv 0.22 Rv0500 Probable pyrroline-5-carboxylate reductase ProC (P5CR) (P5C reductase) 0.31 Rv0189c Probable dihydroxy-acid dehydratase IlvD (dad) — —
Azospirillum sp. SherDot2 0.22 MPMX19_01399 Pyrroline-5-carboxylate reductase 0.74 MPMX19_05356 Dihydroxy-acid dehydratase — —
Rhodopseudomonas palustris CGA009 0.22 TX73_022630 pyrroline-5-carboxylate reductase 0.74 TX73_007515 dihydroxy-acid dehydratase — —
Magnetospirillum magneticum AMB-1 0.22 AMB_RS02820 pyrroline-5-carboxylate reductase 0.73 AMB_RS12770 dihydroxy-acid dehydratase — —
Bacteroides ovatus ATCC 8483 0.22 BACOVA_03587 pyrroline-5-carboxylate reductase 0.62 BACOVA_03302 dihydroxy-acid dehydratase 0.89 22
Azospirillum brasilense Sp245 0.22 AZOBR_RS06245 pyrroline-5-carboxylate reductase 0.74 AZOBR_RS15015 dihydroxy-acid dehydratase — —
Rhodospirillum rubrum S1H 0.21 Rru_A3281 Delta 1-pyrroline-5-carboxylate reductase (NCBI) 0.71 Rru_A1786 Dihydroxy-acid dehydratase (NCBI) — —
Acinetobacter radioresistens SK82 0.21 MPMX26_00572 Pyrroline-5-carboxylate reductase 0.29 MPMX26_03019 Dihydroxy-acid dehydratase 0.71 22
Pontibacter actiniarum KMM 6156, DSM 19842 0.21 CA264_07730 pyrroline-5-carboxylate reductase 0.28 CA264_06935 dihydroxy-acid dehydratase low > 74
Echinicola vietnamensis KMM 6221, DSM 17526 0.20 Echvi_2479 pyrroline-5-carboxylate reductase 0.29 Echvi_2055 dihydroxy-acid dehydratase 0.80 8
Caulobacter crescentus NA1000 Δfur 0.20 CCNA_00528 pyrroline-5-carboxylate reductase 0.72 CCNA_03139 dihydroxy-acid dehydratase low > 67
Caulobacter crescentus NA1000 0.20 CCNA_00528 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.72 CCNA_03139 dihydroxy-acid dehydratase 0.95 5
Mucilaginibacter yixingensis YX-36 DSM 26809 0.19 ABZR88_RS09865 pyrroline-5-carboxylate reductase 0.27 ABZR88_RS11575 dihydroxy-acid dehydratase 0.88 10
Parabacteroides merdae CL09T00C40 0.18 HMPREF1078_RS10620 pyrroline-5-carboxylate reductase 0.65 HMPREF1078_RS16695 dihydroxy-acid dehydratase low > 61
Pedobacter sp. GW460-11-11-14-LB5 0.18 CA265_RS18505 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.27 CA265_RS15795 dihydroxy-acid dehydratase 0.93 20
Sphingomonas koreensis DSMZ 15582 0.17 Ga0059261_3321 pyrroline-5-carboxylate reductase 0.28 Ga0059261_4216 Dihydroxyacid dehydratase/phosphogluconate dehydratase low > 68
Bosea sp. OAE506 0.17 ABIE41_RS11365 pyrroline-5-carboxylate reductase 0.29 ABIE41_RS15690 dihydroxy-acid dehydratase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.14 A4249_RS09840 pyrroline-5-carboxylate reductase dimerization domain-containing protein 0.25 A4249_RS10030 dihydroxy-acid dehydratase 0.97 24

Not shown: 1 genomes with orthologs for b0386 only; 2 genomes with orthologs for b3771 only