Conservation of cofitness between b0243 and b3771 in Escherichia coli BW25113

99 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0243 proA gamma-glutamyl phosphate reductase (NCBI) 1.0 b3771 ilvD dihydroxy-acid dehydratase (NCBI) 0.95 3
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_03397 Gamma-glutamyl phosphate reductase 1.00 OHPLBJKB_04282 Dihydroxy-acid dehydratase low > 73
Escherichia coli ECOR38 0.99 HEPCGN_07775 proA glutamate-5-semialdehyde dehydrogenase 1.00 HEPCGN_13350 ilvD dihydroxy-acid dehydratase low > 85
Escherichia coli BL21 0.99 ECD_00240 gamma-glutamylphosphate reductase 1.00 ECD_03649 dihydroxyacid dehydratase low > 60
Escherichia coli ECOR27 0.99 NOLOHH_02045 proA glutamate-5-semialdehyde dehydrogenase 1.00 NOLOHH_06775 ilvD dihydroxy-acid dehydratase low > 57
Escherichia coli ECRC62 0.99 BNILDI_00240 proA glutamate-5-semialdehyde dehydrogenase 1.00 BNILDI_04750 ilvD dihydroxy-acid dehydratase — —
Escherichia coli Nissle 1917 0.99 ECOLIN_RS01830 glutamate-5-semialdehyde dehydrogenase 0.99 ECOLIN_RS21665 dihydroxy-acid dehydratase 0.48 13
Escherichia coli ECRC102 0.99 NIAGMN_07530 proA glutamate-5-semialdehyde dehydrogenase 1.00 NIAGMN_12395 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC99 0.99 KEDOAH_18485 proA glutamate-5-semialdehyde dehydrogenase 1.00 KEDOAH_13510 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC101 0.99 OKFHMN_09670 proA glutamate-5-semialdehyde dehydrogenase 1.00 OKFHMN_14640 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC98 0.99 JDDGAC_13295 proA glutamate-5-semialdehyde dehydrogenase 1.00 JDDGAC_18260 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC101 0.99 MCAODC_00190 proA glutamate-5-semialdehyde dehydrogenase 1.00 MCAODC_05145 ilvD dihydroxy-acid dehydratase — —
Escherichia fergusonii Becca 0.99 EFB2_03777 Gamma-glutamyl phosphate reductase 0.99 EFB2_04865 Dihydroxy-acid dehydratase low > 86
Enterobacter asburiae PDN3 0.88 EX28DRAFT_2650 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) 0.96 EX28DRAFT_4443 dihydroxy-acid dehydratase 0.75 41
Enterobacter sp. TBS_079 0.88 MPMX20_00928 Gamma-glutamyl phosphate reductase 0.97 MPMX20_04499 Dihydroxy-acid dehydratase 0.95 2
Klebsiella michiganensis M5al 0.86 BWI76_RS05835 gamma-glutamyl-phosphate reductase 0.96 BWI76_RS00975 dihydroxy-acid dehydratase 0.84 8
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.86 GFF4115 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.97 GFF2901 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 78
Dickeya dadantii 3937 0.79 DDA3937_RS16530 glutamate-5-semialdehyde dehydrogenase 0.92 DDA3937_RS20155 dihydroxy-acid dehydratase 0.87 5
Dickeya dianthicola ME23 0.78 DZA65_RS17690 glutamate-5-semialdehyde dehydrogenase 0.91 DZA65_RS21335 dihydroxy-acid dehydratase 0.60 43
Serratia liquefaciens MT49 0.77 IAI46_04435 glutamate-5-semialdehyde dehydrogenase 0.90 IAI46_24345 dihydroxy-acid dehydratase 0.71 35
Pantoea sp. MT58 0.75 IAI47_15115 glutamate-5-semialdehyde dehydrogenase 0.89 IAI47_01035 dihydroxy-acid dehydratase 0.94 9
Erwinia tracheiphila SCR3 0.74 LU632_RS01190 proA glutamate-5-semialdehyde dehydrogenase 0.86 LU632_RS24400 ilvD dihydroxy-acid dehydratase 0.74 30
Dickeya dianthicola 67-19 0.74 HGI48_RS16600 glutamate-5-semialdehyde dehydrogenase 0.91 HGI48_RS20295 dihydroxy-acid dehydratase 0.82 18
Pectobacterium carotovorum WPP14 0.74 HER17_RS04705 glutamate-5-semialdehyde dehydrogenase 0.91 HER17_RS01075 dihydroxy-acid dehydratase 0.97 5
Rahnella sp. WP5 0.73 EX31_RS20975 glutamate-5-semialdehyde dehydrogenase 0.87 EX31_RS15005 dihydroxy-acid dehydratase 0.99 2
Vibrio cholerae E7946 ATCC 55056 0.58 CSW01_11570 glutamate-5-semialdehyde dehydrogenase 0.85 CSW01_00140 dihydroxy-acid dehydratase low > 62
Shewanella loihica PV-4 0.57 Shew_2847 proA gamma-glutamyl phosphate reductase (RefSeq) 0.78 Shew_0292 dihydroxy-acid dehydratase (RefSeq) 0.97 17
Shewanella sp. ANA-3 0.56 Shewana3_0955 proA gamma-glutamyl phosphate reductase (RefSeq) 0.80 Shewana3_0358 dihydroxy-acid dehydratase (RefSeq) 0.97 4
Shewanella oneidensis MR-1 0.56 SO1122 proA gamma-glutamyl phosphate reductase (NCBI ptt file) 0.80 SO4345 ilvD dihydroxy-acid dehydratase (NCBI ptt file) 0.99 5
Shewanella amazonensis SB2B 0.55 Sama_2515 proA gamma-glutamyl phosphate reductase (RefSeq) 0.79 Sama_3279 dihydroxy-acid dehydratase (RefSeq) 0.97 3
Bifidobacterium breve UCC2003 0.44 BBR_RS14075 glutamate-5-semialdehyde dehydrogenase 0.56 BBR_RS17635 dihydroxy-acid dehydratase low > 34
Pseudomonas sp. S08-1 0.44 OH686_09340 Gamma-glutamyl phosphate reductase 0.75 OH686_14100 dihydroxy-acid dehydratase 0.70 37
Pseudomonas fluorescens SBW25 0.44 PFLU_RS26675 glutamate-5-semialdehyde dehydrogenase 0.75 PFLU_RS28535 dihydroxy-acid dehydratase — —
Pseudomonas fluorescens SBW25-INTG 0.44 PFLU_RS26675 glutamate-5-semialdehyde dehydrogenase 0.75 PFLU_RS28535 dihydroxy-acid dehydratase — —
Acinetobacter radioresistens SK82 0.44 MPMX26_00417 Gamma-glutamyl phosphate reductase 0.29 MPMX26_03019 Dihydroxy-acid dehydratase 0.71 35
Pseudomonas simiae WCS417 0.44 PS417_24745 gamma-glutamyl phosphate reductase 0.75 PS417_26890 dihydroxy-acid dehydratase 0.64 16
Pseudomonas syringae pv. syringae B728a ΔmexB 0.44 Psyr_4369 glutamate-5-semialdehyde dehydrogenase 0.74 Psyr_0469 dihydroxyacid dehydratase 0.94 4
Pseudomonas syringae pv. syringae B728a 0.44 Psyr_4369 glutamate-5-semialdehyde dehydrogenase 0.74 Psyr_0469 dihydroxyacid dehydratase 0.92 4
Marinobacter adhaerens HP15 0.43 HP15_601 gamma-glutamyl phosphate reductase 0.70 HP15_595 dihydroxy-acid dehydratase — —
Mycobacterium tuberculosis H37Rv 0.43 Rv2427c Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialdehyde dehydrogenase) 0.31 Rv0189c Probable dihydroxy-acid dehydratase IlvD (dad) — —
Pseudomonas stutzeri RCH2 0.43 Psest_0508 gamma-glutamyl phosphate reductase 0.75 Psest_0234 dihydroxy-acid dehydratase — —
Paraburkholderia sabiae LMG 24235 0.43 QEN71_RS26940 glutamate-5-semialdehyde dehydrogenase 0.74 QEN71_RS21095 dihydroxy-acid dehydratase low > 153
Herbaspirillum seropedicae SmR1 0.43 HSERO_RS02965 gamma-glutamyl phosphate reductase 0.74 HSERO_RS02650 dihydroxy-acid dehydratase low > 78
Dechlorosoma suillum PS 0.42 Dsui_1220 gamma-glutamyl phosphate reductase 0.74 Dsui_1122 dihydroxy-acid dehydratase — —
Pseudomonas fluorescens FW300-N2E2 0.42 Pf6N2E2_4993 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.75 Pf6N2E2_4564 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 103
Pseudomonas sp. RS175 0.42 PFR28_03872 Gamma-glutamyl phosphate reductase 0.75 PFR28_04278 Dihydroxy-acid dehydratase — —
Pseudomonas fluorescens GW456-L13 0.42 PfGW456L13_1356 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.75 PfGW456L13_973 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.44 15
Variovorax sp. SCN45 0.42 GFF6326 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.31 GFF471 Dihydroxy-acid dehydratase (EC 4.2.1.9) — —
Pseudomonas fluorescens FW300-N1B4 0.42 Pf1N1B4_2688 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.75 Pf1N1B4_2303 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 87
Pseudomonas fluorescens FW300-N2C3 0.42 AO356_15290 gamma-glutamyl phosphate reductase 0.75 AO356_13250 dihydroxy-acid dehydratase low > 104
Pseudomonas fluorescens FW300-N2E3 0.42 AO353_06495 gamma-glutamyl phosphate reductase 0.75 AO353_08345 dihydroxy-acid dehydratase 0.67 18
Bacteroides stercoris CC31F 0.42 HMPREF1181_RS03320 glutamate-5-semialdehyde dehydrogenase 0.64 HMPREF1181_RS08335 dihydroxy-acid dehydratase 0.88 36
Pontibacter actiniarum KMM 6156, DSM 19842 0.42 CA264_07720 gamma-glutamyl-phosphate reductase 0.28 CA264_06935 dihydroxy-acid dehydratase low > 74
Castellaniella sp019104865 MT123 0.41 ABCV34_RS00845 glutamate-5-semialdehyde dehydrogenase 0.72 ABCV34_RS14810 dihydroxy-acid dehydratase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.41 GFF2641 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.64 GFF2073 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 90
Ralstonia sp. UNC404CL21Col 0.41 ABZR87_RS01395 glutamate-5-semialdehyde dehydrogenase 0.75 ABZR87_RS00240 dihydroxy-acid dehydratase low > 80
Paraburkholderia bryophila 376MFSha3.1 0.41 H281DRAFT_06324 glutamate-5-semialdehyde dehydrogenase 0.74 H281DRAFT_05312 dihydroxyacid dehydratase low > 103
Pseudomonas putida KT2440 0.41 PP_4811 Gamma-glutamyl phosphate reductase 0.74 PP_5128 Dihydroxy-acid dehydratase low > 96
Burkholderia phytofirmans PsJN 0.41 BPHYT_RS16770 gamma-glutamyl phosphate reductase 0.74 BPHYT_RS10100 dihydroxy-acid dehydratase — —
Rhodanobacter denitrificans MT42 0.41 LRK55_RS02125 glutamate-5-semialdehyde dehydrogenase 0.26 LRK55_RS09960 dihydroxy-acid dehydratase low > 63
Xanthomonas campestris pv. campestris strain 8004 0.41 Xcc-8004.2327.1 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.72 Xcc-8004.451.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.73 41
Rhodanobacter denitrificans FW104-10B01 0.41 LRK54_RS02370 glutamate-5-semialdehyde dehydrogenase 0.26 LRK54_RS10320 dihydroxy-acid dehydratase 0.86 13
Variovorax sp. OAS795 0.40 ABID97_RS04600 glutamate-5-semialdehyde dehydrogenase 0.31 ABID97_RS17500 dihydroxy-acid dehydratase — —
Acidovorax sp. GW101-3H11 0.40 Ac3H11_704 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.74 Ac3H11_955 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 79
Paraburkholderia graminis OAS925 0.40 ABIE53_003523 glutamate-5-semialdehyde dehydrogenase 0.74 ABIE53_006513 dihydroxy-acid dehydratase low > 113
Rhodospirillum rubrum S1H 0.40 Rru_A1238 Gamma-glutamyl phosphate reductase GPR (NCBI) 0.71 Rru_A1786 Dihydroxy-acid dehydratase (NCBI) — —
Ralstonia solanacearum UW163 0.40 UW163_RS07800 glutamate-5-semialdehyde dehydrogenase 0.29 UW163_RS09135 dihydroxy-acid dehydratase — —
Ralstonia solanacearum IBSBF1503 0.40 RALBFv3_RS05825 glutamate-5-semialdehyde dehydrogenase 0.29 RALBFv3_RS04535 dihydroxy-acid dehydratase — —
Alteromonas macleodii MIT1002 0.40 MIT1002_01885 Gamma-glutamyl phosphate reductase 0.79 MIT1002_04041 Dihydroxy-acid dehydratase 0.97 21
Ralstonia solanacearum GMI1000 0.40 RS_RS13715 gamma-glutamyl-phosphate reductase 0.28 RS_RS12105 dihydroxy-acid dehydratase — —
Lysobacter sp. OAE881 0.40 ABIE51_RS13365 glutamate-5-semialdehyde dehydrogenase 0.27 ABIE51_RS17540 dihydroxy-acid dehydratase 0.90 32
Magnetospirillum magneticum AMB-1 0.40 AMB_RS20640 glutamate-5-semialdehyde dehydrogenase 0.73 AMB_RS12770 dihydroxy-acid dehydratase — —
Ralstonia solanacearum PSI07 0.40 RPSI07_RS11475 glutamate-5-semialdehyde dehydrogenase 0.29 RPSI07_RS12840 dihydroxy-acid dehydratase — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.39 ABZR88_RS22165 glutamate-5-semialdehyde dehydrogenase 0.27 ABZR88_RS11575 dihydroxy-acid dehydratase 0.84 7
Pedobacter sp. GW460-11-11-14-LB5 0.39 CA265_RS20850 glutamate-5-semialdehyde dehydrogenase 0.27 CA265_RS15795 dihydroxy-acid dehydratase 0.93 21
Azospirillum brasilense Sp245 0.39 AZOBR_RS04075 gamma-glutamyl phosphate reductase 0.74 AZOBR_RS15015 dihydroxy-acid dehydratase — —
Desulfovibrio vulgaris Hildenborough JW710 0.39 DVU1953 proA gamma-glutamyl phosphate reductase (TIGR) 0.39 DVU3373 ilvD dihydroxy-acid dehydratase (TIGR) 0.85 16
Azospirillum sp. SherDot2 0.39 MPMX19_01943 Gamma-glutamyl phosphate reductase 0.74 MPMX19_05356 Dihydroxy-acid dehydratase — —
Sphingomonas koreensis DSMZ 15582 0.39 Ga0059261_2506 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) 0.28 Ga0059261_4216 Dihydroxyacid dehydratase/phosphogluconate dehydratase 0.98 3
Dyella japonica UNC79MFTsu3.2 0.39 ABZR86_RS08680 glutamate-5-semialdehyde dehydrogenase 0.28 ABZR86_RS15945 dihydroxy-acid dehydratase 0.84 52
Bacteroides thetaiotaomicron VPI-5482 0.39 BT3718 gamma-glutamyl phosphate reductase (NCBI ptt file) 0.63 BT2078 dihydroxy-acid dehydratase (NCBI ptt file) 0.95 8
Dinoroseobacter shibae DFL-12 0.39 Dshi_1469 gamma-glutamyl phosphate reductase (RefSeq) 0.31 Dshi_0129 dihydroxy-acid dehydratase (RefSeq) — —
Bacteroides ovatus ATCC 8483 0.38 BACOVA_03534 glutamate-5-semialdehyde dehydrogenase 0.62 BACOVA_03302 dihydroxy-acid dehydratase 0.96 13
Desulfovibrio vulgaris Miyazaki F 0.38 DvMF_0612 proA gamma-glutamyl phosphate reductase (RefSeq) 0.39 DvMF_2034 dihydroxy-acid dehydratase (RefSeq) 0.85 28
Rhodanobacter sp. FW510-T8 0.37 OKGIIK_09415 proA glutamate-5-semialdehyde dehydrogenase 0.27 OKGIIK_13600 ilvD dihydroxy-acid dehydratase low > 52
Cupriavidus basilensis FW507-4G11 0.37 RR42_RS17530 gamma-glutamyl phosphate reductase 0.29 RR42_RS16210 dihydroxy-acid dehydratase — —
Rhodopseudomonas palustris CGA009 0.37 TX73_000855 glutamate-5-semialdehyde dehydrogenase 0.74 TX73_007515 dihydroxy-acid dehydratase — —
Sinorhizobium meliloti 1021 0.37 SMc03777 gamma-glutamyl phosphate reductase 0.75 SMc04045 dihydroxy-acid dehydratase 0.93 4
Rhizobium sp. OAE497 0.36 ABIE40_RS18925 glutamate-5-semialdehyde dehydrogenase 0.75 ABIE40_RS08005 dihydroxy-acid dehydratase 0.84 70
Phaeobacter inhibens DSM 17395 0.36 PGA1_c15520 gamma-glutamyl phosphate reductase ProA 0.70 PGA1_c29490 dihydroxy-acid dehydratase LivD 0.79 22
Caulobacter crescentus NA1000 Δfur 0.36 CCNA_03543 gamma-glutamyl phosphate reductase 0.72 CCNA_03139 dihydroxy-acid dehydratase low > 67
Caulobacter crescentus NA1000 0.36 CCNA_03543 gamma-glutamyl phosphate reductase 0.72 CCNA_03139 dihydroxy-acid dehydratase 0.92 7
Agrobacterium fabrum C58 0.36 Atu2779 gamma-glutamyl phosphate reductase 0.73 Atu1918 dihydroxy-acid dehydratase — —
Phocaeicola dorei CL03T12C01 0.35 ABI39_RS02875 glutamate-5-semialdehyde dehydrogenase 0.64 ABI39_RS12715 dihydroxy-acid dehydratase 0.87 12
Phocaeicola vulgatus CL09T03C04 0.35 HMPREF1058_RS08645 glutamate-5-semialdehyde dehydrogenase 0.64 HMPREF1058_RS16815 dihydroxy-acid dehydratase 0.88 25
Parabacteroides merdae CL09T00C40 0.35 HMPREF1078_RS10655 glutamate-5-semialdehyde dehydrogenase 0.65 HMPREF1078_RS16695 dihydroxy-acid dehydratase low > 61
Synechococcus elongatus PCC 7942 0.35 Synpcc7942_2265 proA glutamate-5-semialdehyde dehydrogenase 0.75 Synpcc7942_0626 ilvD dihydroxy-acid dehydratase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.34 A4249_RS16120 glutamate-5-semialdehyde dehydrogenase 0.25 A4249_RS10030 dihydroxy-acid dehydratase 0.99 10
Bosea sp. OAE506 0.33 ABIE41_RS07580 glutamate-5-semialdehyde dehydrogenase 0.29 ABIE41_RS15690 dihydroxy-acid dehydratase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.29 Echvi_2633 gamma-glutamylphosphate reductase (EC 1.2.1.41) (from data) 0.29 Echvi_2055 dihydroxy-acid dehydratase 0.88 15

Not shown: 1 genomes with orthologs for b0243 only; 2 genomes with orthologs for b3771 only