Conservation of cofitness between b0386 and b3770 in Escherichia coli BW25113

100 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0386 proC pyrroline-5-carboxylate reductase (NCBI) 1.0 b3770 ilvE branched-chain amino acid aminotransferase (NCBI) 0.88 3
Escherichia coli Nissle 1917 1.00 ECOLIN_RS02345 pyrroline-5-carboxylate reductase 1.00 ECOLIN_RS21660 branched-chain-amino-acid transaminase low > 52
Escherichia coli BL21 1.00 ECD_00333 pyrroline-5-carboxylate reductase, NAD(P)-binding 1.00 ECD_03648 branched-chain amino acid aminotransferase low > 60
Escherichia coli ECRC62 1.00 BNILDI_22950 proC pyrroline-5-carboxylate reductase 1.00 BNILDI_04745 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03288 Pyrroline-5-carboxylate reductase 1.00 OHPLBJKB_04283 Branched-chain-amino-acid aminotransferase low > 73
Escherichia coli ECOR38 1.00 HEPCGN_07250 proC pyrroline-5-carboxylate reductase 1.00 HEPCGN_13355 ilvE branched-chain-amino-acid transaminase low > 85
Escherichia coli ECOR27 1.00 NOLOHH_01535 proC pyrroline-5-carboxylate reductase 1.00 NOLOHH_06780 ilvE branched-chain-amino-acid transaminase low > 57
Escherichia coli ECRC98 1.00 JDDGAC_12265 proC pyrroline-5-carboxylate reductase 1.00 JDDGAC_18265 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC101 1.00 OKFHMN_08610 proC pyrroline-5-carboxylate reductase 1.00 OKFHMN_14645 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC102 1.00 NIAGMN_06665 proC pyrroline-5-carboxylate reductase 1.00 NIAGMN_12400 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC99 1.00 KEDOAH_19355 proC pyrroline-5-carboxylate reductase 1.00 KEDOAH_13505 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC101 1.00 MCAODC_27835 proC pyrroline-5-carboxylate reductase 1.00 MCAODC_05150 ilvE branched-chain-amino-acid transaminase — —
Escherichia fergusonii Becca 0.99 EFB2_03670 Pyrroline-5-carboxylate reductase 1.00 EFB2_04866 Branched-chain-amino-acid aminotransferase low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF4283 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.98 GFF2902 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 78
Klebsiella michiganensis M5al 0.94 BWI76_RS06170 pyrroline-5-carboxylate reductase 0.97 BWI76_RS00970 branched chain amino acid aminotransferase — —
Enterobacter sp. TBS_079 0.93 MPMX20_00976 Pyrroline-5-carboxylate reductase 0.99 MPMX20_04500 Branched-chain-amino-acid aminotransferase low > 85
Enterobacter asburiae PDN3 0.93 EX28DRAFT_2585 pyrroline-5-carboxylate reductase 0.98 EX28DRAFT_4442 branched-chain amino acid aminotransferase, group I low > 76
Erwinia tracheiphila SCR3 0.71 LU632_RS18995 proC pyrroline-5-carboxylate reductase 0.90 LU632_RS24405 branched-chain amino acid transaminase 0.63 19
Pantoea sp. MT58 0.64 IAI47_14945 pyrroline-5-carboxylate reductase 0.91 IAI47_01030 branched-chain amino acid transaminase 0.85 12
Synechococcus elongatus PCC 7942 0.35 Synpcc7942_2058 proC pyrroline-5-carboxylate reductase 0.29 Synpcc7942_1029 ilvE branched-chain amino acid aminotransferase — —
Lysobacter sp. OAE881 0.30 ABIE51_RS16065 pyrroline-5-carboxylate reductase 0.55 ABIE51_RS16505 branched-chain amino acid transaminase low > 62
Dyella japonica UNC79MFTsu3.2 0.29 ABZR86_RS10425 pyrroline-5-carboxylate reductase 0.56 ABZR86_RS15965 branched-chain amino acid transaminase 0.92 9
Shewanella loihica PV-4 0.29 Shew_1136 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.68 Shew_0291 branched-chain amino acid aminotransferase (RefSeq) 0.90 36
Shewanella amazonensis SB2B 0.29 Sama_2478 pyrroline-5-carboxylate reductase (RefSeq) 0.19 Sama_3299 branched-chain amino acid aminotransferase (RefSeq) low > 62
Marinobacter adhaerens HP15 0.29 HP15_287 pyrroline-5-carboxylate reductase 0.43 HP15_436 branched-chain-amino-acid aminotransferase — —
Pseudomonas sp. S08-1 0.28 OH686_10980 pyrroline-5-carboxylate reductase 0.46 OH686_09695 branched-chain amino acid aminotransferase low > 80
Alteromonas macleodii MIT1002 0.28 MIT1002_03062 Pyrroline-5-carboxylate reductase 0.17 MIT1002_00377 Branched-chain-amino-acid aminotransferase 2 0.94 41
Kangiella aquimarina DSM 16071 0.28 B158DRAFT_0197 pyrroline-5-carboxylate reductase 0.20 B158DRAFT_0078 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase low > 40
Pectobacterium carotovorum WPP14 0.28 HER17_RS03805 pyrroline-5-carboxylate reductase 0.90 HER17_RS01070 branched-chain amino acid transaminase — —
Dechlorosoma suillum PS 0.28 Dsui_0602 pyrroline-5-carboxylate reductase 0.47 Dsui_2030 branched-chain amino acid aminotransferase, group I — —
Pseudomonas stutzeri RCH2 0.28 Psest_0283 pyrroline-5-carboxylate reductase 0.46 Psest_0450 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) — —
Shewanella oneidensis MR-1 0.28 SO3354 proC pyrroline-5-carboxylate reductase (NCBI ptt file) 0.19 SO0340 ilvE branched-chain amino acid aminotransferase (NCBI ptt file) 0.87 69
Dickeya dadantii 3937 0.28 DDA3937_RS17305 pyrroline-5-carboxylate reductase 0.91 DDA3937_RS20160 branched-chain-amino-acid transaminase 0.68 30
Rhodanobacter denitrificans FW104-10B01 0.27 LRK54_RS04260 pyrroline-5-carboxylate reductase 0.56 LRK54_RS12020 branched-chain amino acid transaminase low > 59
Acidovorax sp. GW101-3H11 0.27 Ac3H11_788 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.46 Ac3H11_3369 Branched-chain amino acid aminotransferase (EC 2.6.1.42) — —
Rhodanobacter denitrificans MT42 0.27 LRK55_RS04030 pyrroline-5-carboxylate reductase 0.56 LRK55_RS11755 branched-chain amino acid transaminase — —
Rhodanobacter sp. FW510-T8 0.27 OKGIIK_11135 proC pyrroline-5-carboxylate reductase 0.56 OKGIIK_11840 ilvE branched-chain amino acid transaminase low > 52
Pseudomonas putida KT2440 0.27 PP_5095 pyrroline-5-carboxylate reductase 0.19 PP_3511 Branched-chain-amino-acid aminotransferase 0.42 37
Paraburkholderia graminis OAS925 0.27 ABIE53_000840 pyrroline-5-carboxylate reductase 0.43 ABIE53_003432 branched-chain amino acid aminotransferase low > 113
Shewanella sp. ANA-3 0.27 Shewana3_1193 pyrroline-5-carboxylate reductase (RefSeq) 0.19 Shewana3_3830 branched-chain amino acid aminotransferase (RefSeq) low > 73
Vibrio cholerae E7946 ATCC 55056 0.27 CSW01_02450 pyrroline-5-carboxylate reductase 0.75 CSW01_00145 branched-chain-amino-acid transaminase low > 62
Burkholderia phytofirmans PsJN 0.27 BPHYT_RS03490 pyrroline-5-carboxylate reductase 0.43 BPHYT_RS16285 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) — —
Paraburkholderia bryophila 376MFSha3.1 0.27 H281DRAFT_04679 pyrroline-5-carboxylate reductase 0.43 H281DRAFT_04193 branched chain amino acid aminotransferase apoenzyme low > 103
Pseudomonas simiae WCS417 0.27 PS417_26730 pyrroline-5-carboxylate reductase 0.21 PS417_17565 branched-chain amino acid aminotransferase low > 88
Serratia liquefaciens MT49 0.26 IAI46_21415 pyrroline-5-carboxylate reductase 0.92 IAI46_24350 branched-chain-amino-acid transaminase low > 86
Dickeya dianthicola 67-19 0.26 HGI48_RS17350 pyrroline-5-carboxylate reductase 0.90 HGI48_RS20300 branched-chain-amino-acid transaminase — —
Dickeya dianthicola ME23 0.26 DZA65_RS18440 pyrroline-5-carboxylate reductase 0.91 DZA65_RS21340 branched-chain amino acid transaminase — —
Ralstonia solanacearum PSI07 0.26 RPSI07_RS11720 pyrroline-5-carboxylate reductase 0.45 RPSI07_RS21175 branched-chain amino acid transaminase low > 81
Pseudomonas fluorescens SBW25 0.26 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.21 PFLU_RS19375 branched-chain amino acid aminotransferase — —
Ralstonia sp. UNC404CL21Col 0.26 ABZR87_RS01230 pyrroline-5-carboxylate reductase 0.25 ABZR87_RS18540 branched-chain amino acid aminotransferase — —
Pseudomonas fluorescens SBW25-INTG 0.26 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.21 PFLU_RS19375 branched-chain amino acid aminotransferase — —
Ralstonia solanacearum UW163 0.26 UW163_RS08045 pyrroline-5-carboxylate reductase 0.46 UW163_RS01455 branched-chain amino acid transaminase — —
Ralstonia solanacearum IBSBF1503 0.26 RALBFv3_RS05580 pyrroline-5-carboxylate reductase 0.46 RALBFv3_RS12155 branched-chain amino acid transaminase 0.43 70
Cupriavidus basilensis FW507-4G11 0.26 RR42_RS17360 pyrroline-5-carboxylate reductase 0.20 RR42_RS25890 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) — —
Desulfovibrio vulgaris Hildenborough JW710 0.26 DVU2332 proC pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.46 DVU3197 ilvE branched-chain amino acid aminotransferase (TIGR) 0.87 3
Variovorax sp. SCN45 0.26 GFF5553 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.44 GFF5079 Branched-chain amino acid aminotransferase (EC 2.6.1.42) — —
Rahnella sp. WP5 0.26 EX31_RS02690 pyrroline-5-carboxylate reductase 0.90 EX31_RS15000 branched-chain amino acid transaminase 0.91 59
Pseudomonas sp. RS175 0.26 PFR28_04243 Pyrroline-5-carboxylate reductase 0.21 PFR28_02449 putative branched-chain-amino-acid aminotransferase — —
Paraburkholderia sabiae LMG 24235 0.26 QEN71_RS26600 pyrroline-5-carboxylate reductase 0.44 QEN71_RS02410 branched-chain amino acid transaminase low > 153
Pseudomonas fluorescens FW300-N2E3 0.26 AO353_08165 pyrroline-5-carboxylate reductase 0.20 AO353_26655 branched-chain amino acid aminotransferase low > 101
Hydrogenophaga sp. GW460-11-11-14-LB1 0.25 GFF2806 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.46 GFF1835 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 90
Ralstonia solanacearum GMI1000 0.25 RS_RS13440 pyrroline-5-carboxylate reductase 0.45 RS_RS02840 branched-chain amino acid transaminase — —
Herbaspirillum seropedicae SmR1 0.25 HSERO_RS18990 pyrroline-5-carboxylate reductase 0.44 HSERO_RS03330 branched-chain amino acid aminotransferase low > 78
Bifidobacterium breve UCC2003 0.25 BBR_RS14625 pyrroline-5-carboxylate reductase 0.17 BBR_RS15210 branched-chain amino acid aminotransferase low > 34
Pseudomonas syringae pv. syringae B728a ΔmexB 0.25 Psyr_0476 pyrroline-5-carboxylate reductase 0.22 Psyr_1148 branched chain amino acid aminotransferase apoenzyme low > 86
Desulfovibrio vulgaris Miyazaki F 0.25 DvMF_3161 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.46 DvMF_2268 branched-chain amino acid aminotransferase (RefSeq) low > 51
Pseudomonas fluorescens GW456-L13 0.25 PfGW456L13_1010 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.27 PfGW456L13_4923 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 87
Pseudomonas syringae pv. syringae B728a 0.25 Psyr_0476 pyrroline-5-carboxylate reductase 0.22 Psyr_1148 branched chain amino acid aminotransferase apoenzyme — —
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_2341 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.22 Pf1N1B4_4476 Branched-chain amino acid aminotransferase (EC 2.6.1.42) — —
Phocaeicola dorei CL03T12C01 0.25 ABI39_RS02960 pyrroline-5-carboxylate reductase 0.18 ABI39_RS01415 branched-chain amino acid aminotransferase 0.61 72
Phocaeicola vulgatus CL09T03C04 0.25 HMPREF1058_RS08830 pyrroline-5-carboxylate reductase 0.18 HMPREF1058_RS02220 branched-chain amino acid aminotransferase low > 67
Xanthomonas campestris pv. campestris strain 8004 0.24 Xcc-8004.1710.1 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.19 Xcc-8004.4199.1 Branched-chain amino acid aminotransferase (EC 2.6.1.42) 0.45 71
Agrobacterium fabrum C58 0.24 Atu2209 pyrroline-5-carboxylate reductase 0.18 Atu0871 branched-chain-amino-acid aminotransferase low > 89
Pseudomonas fluorescens FW300-N2E2 0.24 Pf6N2E2_4600 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.21 Pf6N2E2_477 Branched-chain amino acid aminotransferase (EC 2.6.1.42) — —
Variovorax sp. OAS795 0.24 ABID97_RS01555 pyrroline-5-carboxylate reductase 0.44 ABID97_RS03790 branched-chain amino acid transaminase — —
Phaeobacter inhibens DSM 17395 0.24 PGA1_c24700 pyrroline-5-carboxylate reductase ProC 0.29 PGA1_c34110 branched-chain-amino-acid aminotransferase IlvE 0.82 19
Pseudomonas fluorescens FW300-N2C3 0.24 AO356_13420 pyrroline-5-carboxylate reductase 0.21 AO356_22970 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) — —
Rhizobium sp. OAE497 0.23 ABIE40_RS13005 pyrroline-5-carboxylate reductase 0.19 ABIE40_RS22240 branched-chain amino acid aminotransferase low > 107
Castellaniella sp019104865 MT123 0.23 ABCV34_RS03610 pyrroline-5-carboxylate reductase 0.45 ABCV34_RS07930 branched-chain amino acid transaminase low > 48
Sinorhizobium meliloti 1021 0.23 SMc02677 pyrroline-5-carboxylate reductase 0.21 SMc02896 branched-chain amino acid aminotransferase low > 103
Bacteroides thetaiotaomicron VPI-5482 0.23 BT3757 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.19 BT3892 branched-chain amino acid aminotransferase (NCBI ptt file) — —
Dinoroseobacter shibae DFL-12 0.23 Dshi_2645 pyrroline-5-carboxylate reductase (RefSeq) 0.26 Dshi_3301 branched-chain amino acid aminotransferase (RefSeq) — —
Azospirillum sp. SherDot2 0.22 MPMX19_01399 Pyrroline-5-carboxylate reductase 0.18 MPMX19_02406 Branched-chain-amino-acid aminotransferase — —
Mycobacterium tuberculosis H37Rv 0.22 Rv0500 Probable pyrroline-5-carboxylate reductase ProC (P5CR) (P5C reductase) 0.19 Rv2210c Branched-chain amino acid transaminase IlvE — —
Bacteroides stercoris CC31F 0.22 HMPREF1181_RS03440 pyrroline-5-carboxylate reductase 0.19 HMPREF1181_RS06865 branched-chain amino acid aminotransferase low > 56
Rhodopseudomonas palustris CGA009 0.22 TX73_022630 pyrroline-5-carboxylate reductase 0.18 TX73_022650 branched-chain amino acid aminotransferase — —
Magnetospirillum magneticum AMB-1 0.22 AMB_RS02820 pyrroline-5-carboxylate reductase 0.31 AMB_RS02850 branched-chain amino acid aminotransferase — —
Azospirillum brasilense Sp245 0.22 AZOBR_RS06245 pyrroline-5-carboxylate reductase 0.31 AZOBR_RS16425 branched-chain amino acid aminotransferase — —
Bacteroides ovatus ATCC 8483 0.22 BACOVA_03587 pyrroline-5-carboxylate reductase 0.30 BACOVA_03679 branched-chain-amino-acid transaminase low > 94
Rhodospirillum rubrum S1H 0.21 Rru_A3281 Delta 1-pyrroline-5-carboxylate reductase (NCBI) 0.32 Rru_A2223 Branched-chain amino acid aminotransferase I (NCBI) — —
Acinetobacter radioresistens SK82 0.21 MPMX26_00572 Pyrroline-5-carboxylate reductase 0.40 MPMX26_00445 Branched-chain-amino-acid aminotransferase low > 36
Pontibacter actiniarum KMM 6156, DSM 19842 0.21 CA264_07730 pyrroline-5-carboxylate reductase 0.32 CA264_06940 branched-chain amino acid aminotransferase low > 74
Echinicola vietnamensis KMM 6221, DSM 17526 0.20 Echvi_2479 pyrroline-5-carboxylate reductase 0.18 Echvi_2202 branched-chain amino acid aminotransferase, group II low > 79
Caulobacter crescentus NA1000 Δfur 0.20 CCNA_00528 pyrroline-5-carboxylate reductase 0.31 CCNA_03024 branched-chain amino acid aminotransferase low > 67
Caulobacter crescentus NA1000 0.20 CCNA_00528 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.31 CCNA_03024 branched-chain amino acid aminotransferase low > 66
Mucilaginibacter yixingensis YX-36 DSM 26809 0.19 ABZR88_RS09865 pyrroline-5-carboxylate reductase 0.16 ABZR88_RS22095 branched-chain amino acid aminotransferase — —
Parabacteroides merdae CL09T00C40 0.18 HMPREF1078_RS10620 pyrroline-5-carboxylate reductase 0.19 HMPREF1078_RS07855 branched-chain amino acid aminotransferase low > 61
Pedobacter sp. GW460-11-11-14-LB5 0.18 CA265_RS18505 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.29 CA265_RS15785 branched-chain-amino-acid transaminase low > 88
Sphingomonas koreensis DSMZ 15582 0.17 Ga0059261_3321 pyrroline-5-carboxylate reductase 0.23 Ga0059261_3811 branched-chain amino acid aminotransferase, group II low > 68
Bosea sp. OAE506 0.17 ABIE41_RS11365 pyrroline-5-carboxylate reductase 0.28 ABIE41_RS11405 branched-chain amino acid aminotransferase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.14 A4249_RS09840 pyrroline-5-carboxylate reductase dimerization domain-containing protein 0.27 A4249_RS09820 branched-chain amino acid aminotransferase — —

Not shown: 0 genomes with orthologs for b0386 only; 2 genomes with orthologs for b3770 only