Conservation of cofitness between b0243 and b3770 in Escherichia coli BW25113

100 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0243 proA gamma-glutamyl phosphate reductase (NCBI) 1.0 b3770 ilvE branched-chain amino acid aminotransferase (NCBI) 0.96 2
Escherichia coli BL21 0.99 ECD_00240 gamma-glutamylphosphate reductase 1.00 ECD_03648 branched-chain amino acid aminotransferase 0.72 19
Escherichia coli ECOR27 0.99 NOLOHH_02045 proA glutamate-5-semialdehyde dehydrogenase 1.00 NOLOHH_06780 ilvE branched-chain-amino-acid transaminase low > 57
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_03397 Gamma-glutamyl phosphate reductase 1.00 OHPLBJKB_04283 Branched-chain-amino-acid aminotransferase low > 73
Escherichia coli ECOR38 0.99 HEPCGN_07775 proA glutamate-5-semialdehyde dehydrogenase 1.00 HEPCGN_13355 ilvE branched-chain-amino-acid transaminase low > 85
Escherichia coli ECRC62 0.99 BNILDI_00240 proA glutamate-5-semialdehyde dehydrogenase 1.00 BNILDI_04745 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli Nissle 1917 0.99 ECOLIN_RS01830 glutamate-5-semialdehyde dehydrogenase 1.00 ECOLIN_RS21660 branched-chain-amino-acid transaminase low > 52
Escherichia coli ECRC99 0.99 KEDOAH_18485 proA glutamate-5-semialdehyde dehydrogenase 1.00 KEDOAH_13505 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC102 0.99 NIAGMN_07530 proA glutamate-5-semialdehyde dehydrogenase 1.00 NIAGMN_12400 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC101 0.99 OKFHMN_09670 proA glutamate-5-semialdehyde dehydrogenase 1.00 OKFHMN_14645 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC98 0.99 JDDGAC_13295 proA glutamate-5-semialdehyde dehydrogenase 1.00 JDDGAC_18265 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC101 0.99 MCAODC_00190 proA glutamate-5-semialdehyde dehydrogenase 1.00 MCAODC_05150 ilvE branched-chain-amino-acid transaminase — —
Escherichia fergusonii Becca 0.99 EFB2_03777 Gamma-glutamyl phosphate reductase 1.00 EFB2_04866 Branched-chain-amino-acid aminotransferase low > 86
Enterobacter asburiae PDN3 0.88 EX28DRAFT_2650 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) 0.98 EX28DRAFT_4442 branched-chain amino acid aminotransferase, group I 0.74 47
Enterobacter sp. TBS_079 0.88 MPMX20_00928 Gamma-glutamyl phosphate reductase 0.99 MPMX20_04500 Branched-chain-amino-acid aminotransferase low > 85
Klebsiella michiganensis M5al 0.86 BWI76_RS05835 gamma-glutamyl-phosphate reductase 0.97 BWI76_RS00970 branched chain amino acid aminotransferase 0.48 90
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.86 GFF4115 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.98 GFF2902 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 78
Dickeya dadantii 3937 0.79 DDA3937_RS16530 glutamate-5-semialdehyde dehydrogenase 0.91 DDA3937_RS20160 branched-chain-amino-acid transaminase 0.66 65
Dickeya dianthicola ME23 0.78 DZA65_RS17690 glutamate-5-semialdehyde dehydrogenase 0.91 DZA65_RS21340 branched-chain amino acid transaminase low > 75
Serratia liquefaciens MT49 0.77 IAI46_04435 glutamate-5-semialdehyde dehydrogenase 0.92 IAI46_24350 branched-chain-amino-acid transaminase low > 86
Pantoea sp. MT58 0.75 IAI47_15115 glutamate-5-semialdehyde dehydrogenase 0.91 IAI47_01030 branched-chain amino acid transaminase 0.94 7
Erwinia tracheiphila SCR3 0.74 LU632_RS01190 proA glutamate-5-semialdehyde dehydrogenase 0.90 LU632_RS24405 branched-chain amino acid transaminase 0.64 54
Dickeya dianthicola 67-19 0.74 HGI48_RS16600 glutamate-5-semialdehyde dehydrogenase 0.90 HGI48_RS20300 branched-chain-amino-acid transaminase low > 71
Pectobacterium carotovorum WPP14 0.74 HER17_RS04705 glutamate-5-semialdehyde dehydrogenase 0.90 HER17_RS01070 branched-chain amino acid transaminase low > 75
Rahnella sp. WP5 0.73 EX31_RS20975 glutamate-5-semialdehyde dehydrogenase 0.90 EX31_RS15000 branched-chain amino acid transaminase 0.89 67
Vibrio cholerae E7946 ATCC 55056 0.58 CSW01_11570 glutamate-5-semialdehyde dehydrogenase 0.75 CSW01_00145 branched-chain-amino-acid transaminase low > 62
Shewanella loihica PV-4 0.57 Shew_2847 proA gamma-glutamyl phosphate reductase (RefSeq) 0.68 Shew_0291 branched-chain amino acid aminotransferase (RefSeq) 0.92 42
Shewanella sp. ANA-3 0.56 Shewana3_0955 proA gamma-glutamyl phosphate reductase (RefSeq) 0.19 Shewana3_3830 branched-chain amino acid aminotransferase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.56 SO1122 proA gamma-glutamyl phosphate reductase (NCBI ptt file) 0.19 SO0340 ilvE branched-chain amino acid aminotransferase (NCBI ptt file) 0.87 68
Shewanella amazonensis SB2B 0.55 Sama_2515 proA gamma-glutamyl phosphate reductase (RefSeq) 0.19 Sama_3299 branched-chain amino acid aminotransferase (RefSeq) low > 62
Bifidobacterium breve UCC2003 0.44 BBR_RS14075 glutamate-5-semialdehyde dehydrogenase 0.17 BBR_RS15210 branched-chain amino acid aminotransferase low > 34
Pseudomonas fluorescens SBW25 0.44 PFLU_RS26675 glutamate-5-semialdehyde dehydrogenase 0.21 PFLU_RS19375 branched-chain amino acid aminotransferase — —
Pseudomonas fluorescens SBW25-INTG 0.44 PFLU_RS26675 glutamate-5-semialdehyde dehydrogenase 0.21 PFLU_RS19375 branched-chain amino acid aminotransferase — —
Pseudomonas sp. S08-1 0.44 OH686_09340 Gamma-glutamyl phosphate reductase 0.46 OH686_09695 branched-chain amino acid aminotransferase low > 80
Pseudomonas simiae WCS417 0.44 PS417_24745 gamma-glutamyl phosphate reductase 0.21 PS417_17565 branched-chain amino acid aminotransferase 0.33 84
Acinetobacter radioresistens SK82 0.44 MPMX26_00417 Gamma-glutamyl phosphate reductase 0.40 MPMX26_00445 Branched-chain-amino-acid aminotransferase low > 36
Pseudomonas syringae pv. syringae B728a 0.44 Psyr_4369 glutamate-5-semialdehyde dehydrogenase 0.22 Psyr_1148 branched chain amino acid aminotransferase apoenzyme 0.59 64
Pseudomonas syringae pv. syringae B728a ΔmexB 0.44 Psyr_4369 glutamate-5-semialdehyde dehydrogenase 0.22 Psyr_1148 branched chain amino acid aminotransferase apoenzyme low > 86
Marinobacter adhaerens HP15 0.43 HP15_601 gamma-glutamyl phosphate reductase 0.43 HP15_436 branched-chain-amino-acid aminotransferase — —
Mycobacterium tuberculosis H37Rv 0.43 Rv2427c Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialdehyde dehydrogenase) 0.19 Rv2210c Branched-chain amino acid transaminase IlvE — —
Pseudomonas stutzeri RCH2 0.43 Psest_0508 gamma-glutamyl phosphate reductase 0.46 Psest_0450 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) low > 67
Paraburkholderia sabiae LMG 24235 0.43 QEN71_RS26940 glutamate-5-semialdehyde dehydrogenase 0.44 QEN71_RS02410 branched-chain amino acid transaminase low > 153
Herbaspirillum seropedicae SmR1 0.43 HSERO_RS02965 gamma-glutamyl phosphate reductase 0.44 HSERO_RS03330 branched-chain amino acid aminotransferase low > 78
Dechlorosoma suillum PS 0.42 Dsui_1220 gamma-glutamyl phosphate reductase 0.47 Dsui_2030 branched-chain amino acid aminotransferase, group I — —
Pseudomonas sp. RS175 0.42 PFR28_03872 Gamma-glutamyl phosphate reductase 0.21 PFR28_02449 putative branched-chain-amino-acid aminotransferase — —
Pseudomonas fluorescens FW300-N2E2 0.42 Pf6N2E2_4993 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.21 Pf6N2E2_477 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 103
Pseudomonas fluorescens GW456-L13 0.42 PfGW456L13_1356 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.27 PfGW456L13_4923 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 87
Variovorax sp. SCN45 0.42 GFF6326 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.44 GFF5079 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 127
Pseudomonas fluorescens FW300-N2C3 0.42 AO356_15290 gamma-glutamyl phosphate reductase 0.21 AO356_22970 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) low > 104
Pseudomonas fluorescens FW300-N2E3 0.42 AO353_06495 gamma-glutamyl phosphate reductase 0.20 AO353_26655 branched-chain amino acid aminotransferase low > 101
Pseudomonas fluorescens FW300-N1B4 0.42 Pf1N1B4_2688 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.22 Pf1N1B4_4476 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 87
Bacteroides stercoris CC31F 0.42 HMPREF1181_RS03320 glutamate-5-semialdehyde dehydrogenase 0.19 HMPREF1181_RS06865 branched-chain amino acid aminotransferase low > 56
Pontibacter actiniarum KMM 6156, DSM 19842 0.42 CA264_07720 gamma-glutamyl-phosphate reductase 0.32 CA264_06940 branched-chain amino acid aminotransferase low > 74
Castellaniella sp019104865 MT123 0.41 ABCV34_RS00845 glutamate-5-semialdehyde dehydrogenase 0.45 ABCV34_RS07930 branched-chain amino acid transaminase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.41 GFF2641 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.46 GFF1835 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 90
Ralstonia sp. UNC404CL21Col 0.41 ABZR87_RS01395 glutamate-5-semialdehyde dehydrogenase 0.25 ABZR87_RS18540 branched-chain amino acid aminotransferase low > 80
Kangiella aquimarina DSM 16071 0.41 B158DRAFT_1470 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) 0.20 B158DRAFT_0078 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase low > 40
Paraburkholderia bryophila 376MFSha3.1 0.41 H281DRAFT_06324 glutamate-5-semialdehyde dehydrogenase 0.43 H281DRAFT_04193 branched chain amino acid aminotransferase apoenzyme low > 103
Burkholderia phytofirmans PsJN 0.41 BPHYT_RS16770 gamma-glutamyl phosphate reductase 0.43 BPHYT_RS16285 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) — —
Pseudomonas putida KT2440 0.41 PP_4811 Gamma-glutamyl phosphate reductase 0.19 PP_3511 Branched-chain-amino-acid aminotransferase low > 96
Rhodanobacter denitrificans MT42 0.41 LRK55_RS02125 glutamate-5-semialdehyde dehydrogenase 0.56 LRK55_RS11755 branched-chain amino acid transaminase low > 63
Rhodanobacter denitrificans FW104-10B01 0.41 LRK54_RS02370 glutamate-5-semialdehyde dehydrogenase 0.56 LRK54_RS12020 branched-chain amino acid transaminase low > 59
Xanthomonas campestris pv. campestris strain 8004 0.41 Xcc-8004.2327.1 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.19 Xcc-8004.4199.1 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 74
Variovorax sp. OAS795 0.40 ABID97_RS04600 glutamate-5-semialdehyde dehydrogenase 0.44 ABID97_RS03790 branched-chain amino acid transaminase — —
Acidovorax sp. GW101-3H11 0.40 Ac3H11_704 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.46 Ac3H11_3369 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 79
Paraburkholderia graminis OAS925 0.40 ABIE53_003523 glutamate-5-semialdehyde dehydrogenase 0.43 ABIE53_003432 branched-chain amino acid aminotransferase low > 113
Ralstonia solanacearum UW163 0.40 UW163_RS07800 glutamate-5-semialdehyde dehydrogenase 0.46 UW163_RS01455 branched-chain amino acid transaminase — —
Alteromonas macleodii MIT1002 0.40 MIT1002_01885 Gamma-glutamyl phosphate reductase 0.17 MIT1002_00377 Branched-chain-amino-acid aminotransferase 2 0.96 37
Rhodospirillum rubrum S1H 0.40 Rru_A1238 Gamma-glutamyl phosphate reductase GPR (NCBI) 0.32 Rru_A2223 Branched-chain amino acid aminotransferase I (NCBI) — —
Ralstonia solanacearum IBSBF1503 0.40 RALBFv3_RS05825 glutamate-5-semialdehyde dehydrogenase 0.46 RALBFv3_RS12155 branched-chain amino acid transaminase low > 76
Ralstonia solanacearum GMI1000 0.40 RS_RS13715 gamma-glutamyl-phosphate reductase 0.45 RS_RS02840 branched-chain amino acid transaminase — —
Ralstonia solanacearum PSI07 0.40 RPSI07_RS11475 glutamate-5-semialdehyde dehydrogenase 0.45 RPSI07_RS21175 branched-chain amino acid transaminase low > 81
Magnetospirillum magneticum AMB-1 0.40 AMB_RS20640 glutamate-5-semialdehyde dehydrogenase 0.31 AMB_RS02850 branched-chain amino acid aminotransferase — —
Lysobacter sp. OAE881 0.40 ABIE51_RS13365 glutamate-5-semialdehyde dehydrogenase 0.55 ABIE51_RS16505 branched-chain amino acid transaminase low > 62
Mucilaginibacter yixingensis YX-36 DSM 26809 0.39 ABZR88_RS22165 glutamate-5-semialdehyde dehydrogenase 0.16 ABZR88_RS22095 branched-chain amino acid aminotransferase — —
Azospirillum brasilense Sp245 0.39 AZOBR_RS04075 gamma-glutamyl phosphate reductase 0.31 AZOBR_RS16425 branched-chain amino acid aminotransferase — —
Pedobacter sp. GW460-11-11-14-LB5 0.39 CA265_RS20850 glutamate-5-semialdehyde dehydrogenase 0.29 CA265_RS15785 branched-chain-amino-acid transaminase low > 88
Sphingomonas koreensis DSMZ 15582 0.39 Ga0059261_2506 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) 0.23 Ga0059261_3811 branched-chain amino acid aminotransferase, group II 0.97 13
Desulfovibrio vulgaris Hildenborough JW710 0.39 DVU1953 proA gamma-glutamyl phosphate reductase (TIGR) 0.46 DVU3197 ilvE branched-chain amino acid aminotransferase (TIGR) 0.88 4
Azospirillum sp. SherDot2 0.39 MPMX19_01943 Gamma-glutamyl phosphate reductase 0.18 MPMX19_02406 Branched-chain-amino-acid aminotransferase — —
Dyella japonica UNC79MFTsu3.2 0.39 ABZR86_RS08680 glutamate-5-semialdehyde dehydrogenase 0.56 ABZR86_RS15965 branched-chain amino acid transaminase 0.88 25
Bacteroides thetaiotaomicron VPI-5482 0.39 BT3718 gamma-glutamyl phosphate reductase (NCBI ptt file) 0.19 BT3892 branched-chain amino acid aminotransferase (NCBI ptt file) — —
Dinoroseobacter shibae DFL-12 0.39 Dshi_1469 gamma-glutamyl phosphate reductase (RefSeq) 0.26 Dshi_3301 branched-chain amino acid aminotransferase (RefSeq) — —
Bacteroides ovatus ATCC 8483 0.38 BACOVA_03534 glutamate-5-semialdehyde dehydrogenase 0.30 BACOVA_03679 branched-chain-amino-acid transaminase low > 94
Desulfovibrio vulgaris Miyazaki F 0.38 DvMF_0612 proA gamma-glutamyl phosphate reductase (RefSeq) 0.46 DvMF_2268 branched-chain amino acid aminotransferase (RefSeq) low > 51
Rhodanobacter sp. FW510-T8 0.37 OKGIIK_09415 proA glutamate-5-semialdehyde dehydrogenase 0.56 OKGIIK_11840 ilvE branched-chain amino acid transaminase low > 52
Cupriavidus basilensis FW507-4G11 0.37 RR42_RS17530 gamma-glutamyl phosphate reductase 0.20 RR42_RS25890 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) low > 128
Rhodopseudomonas palustris CGA009 0.37 TX73_000855 glutamate-5-semialdehyde dehydrogenase 0.18 TX73_022650 branched-chain amino acid aminotransferase — —
Sinorhizobium meliloti 1021 0.37 SMc03777 gamma-glutamyl phosphate reductase 0.21 SMc02896 branched-chain amino acid aminotransferase low > 103
Rhizobium sp. OAE497 0.36 ABIE40_RS18925 glutamate-5-semialdehyde dehydrogenase 0.19 ABIE40_RS22240 branched-chain amino acid aminotransferase low > 107
Phaeobacter inhibens DSM 17395 0.36 PGA1_c15520 gamma-glutamyl phosphate reductase ProA 0.29 PGA1_c34110 branched-chain-amino-acid aminotransferase IlvE 0.79 17
Caulobacter crescentus NA1000 0.36 CCNA_03543 gamma-glutamyl phosphate reductase 0.31 CCNA_03024 branched-chain amino acid aminotransferase low > 66
Caulobacter crescentus NA1000 Δfur 0.36 CCNA_03543 gamma-glutamyl phosphate reductase 0.31 CCNA_03024 branched-chain amino acid aminotransferase low > 67
Agrobacterium fabrum C58 0.36 Atu2779 gamma-glutamyl phosphate reductase 0.18 Atu0871 branched-chain-amino-acid aminotransferase — —
Phocaeicola dorei CL03T12C01 0.35 ABI39_RS02875 glutamate-5-semialdehyde dehydrogenase 0.18 ABI39_RS01415 branched-chain amino acid aminotransferase 0.60 64
Parabacteroides merdae CL09T00C40 0.35 HMPREF1078_RS10655 glutamate-5-semialdehyde dehydrogenase 0.19 HMPREF1078_RS07855 branched-chain amino acid aminotransferase low > 61
Phocaeicola vulgatus CL09T03C04 0.35 HMPREF1058_RS08645 glutamate-5-semialdehyde dehydrogenase 0.18 HMPREF1058_RS02220 branched-chain amino acid aminotransferase low > 67
Synechococcus elongatus PCC 7942 0.35 Synpcc7942_2265 proA glutamate-5-semialdehyde dehydrogenase 0.29 Synpcc7942_1029 ilvE branched-chain amino acid aminotransferase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.34 A4249_RS16120 glutamate-5-semialdehyde dehydrogenase 0.27 A4249_RS09820 branched-chain amino acid aminotransferase — —
Bosea sp. OAE506 0.33 ABIE41_RS07580 glutamate-5-semialdehyde dehydrogenase 0.28 ABIE41_RS11405 branched-chain amino acid aminotransferase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.29 Echvi_2633 gamma-glutamylphosphate reductase (EC 1.2.1.41) (from data) 0.18 Echvi_2202 branched-chain amino acid aminotransferase, group II low > 79

Not shown: 0 genomes with orthologs for b0243 only; 2 genomes with orthologs for b3770 only