| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Variovorax sp. SCN45 | GFF3787 | | Biotin carboxylase (EC 6.3.4.14) | insig. | 100 | 100 |
| o | Variovorax sp. OAS795 | ABID97_RS00115 | | carboxyl transferase domain-containing protein | insig. | 90 | 100 |
| o | Acidovorax sp. GW101-3H11 | Ac3H11_4479 | | Biotin carboxylase (EC 6.3.4.14) | insig. | 72 | 100 |
| o | Pseudomonas sp. S08-1 | OH686_15770 | | Probable pyruvate carboxylase | insig. | 58 | 100 |
| o | Ralstonia sp. UNC404CL21Col | ABZR87_RS15560 | | carboxyl transferase domain-containing protein | insig. | 59 | 100 |
| o | Cupriavidus basilensis FW507-4G11 | RR42_RS18165 | | carbamoyl-phosphate synthase large subunit | insig. | 59 | 100 |
| o | Rhodopseudomonas palustris CGA009 | TX73_007450 | | carboxyl transferase domain-containing protein | insig. | 56 | 100 |
| o | Marinobacter adhaerens HP15 | HP15_2750 | | protein containing carbamoyl phosphate synthetase, large subunit, ATP-binding / carboxyl transferase / carbamoyl phosphate synthase, large subunit, N-terminal / biotin carboxylase, C-terminal / biotin/lipoyl attachment | insig. | 55 | 100 |
| o | Pseudomonas segetis P6 | ACVTMO_RS04980 | | carboxyl transferase domain-containing protein | insig. | 56 | 100 |
| o | Pseudomonas aeruginosa MRSN321 | DY961_RS05915 | | carboxyl transferase domain-containing protein | insig. | 57 | 100 |
| o | Pseudomonas aeruginosa PUPa3 | DQ20_RS46885 | | carboxyl transferase domain-containing protein | insig. | 57 | 100 |
| o | Pseudomonas aeruginosa PA14 | IKLFDK_06645 | | carbamoyl-phosphate synthase large subunit | insig. | 57 | 100 |
| o | Caulobacter crescentus NA1000 | CCNA_03320 | | biotin carboxylase | insig. | 57 | 99 |
| o | Caulobacter crescentus NA1000 Δfur | CCNA_03320 | | biotin carboxylase | cofit | 57 | 99 |
| o | Shewanella loihica PV-4 | Shew_2867 | | pyruvate carboxylase, propionyl-CoA carboxylase (RefSeq) | insig. | 51 | 100 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2730 | | Biotin carboxylase (EC 6.3.4.14) | insig. | 68 | 55 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_1379 | accC | acetyl-CoA carboxylase biotin carboxylase subunit | no data | 46 | 41 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS13980 | | acetyl-CoA carboxylase biotin carboxylase subunit | no data | 44 | 41 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_07760 | | acetyl-CoA carboxylase biotin carboxylase subunit | no data | 43 | 41 |
| | Rhodospirillum rubrum S1H | Rru_A2435 | | Acetyl-CoA carboxylase, biotin carboxylase (NCBI) | no data | 46 | 41 |
| | Agrobacterium fabrum C58 | Atu3913 | | biotin carboxylase | strong | 41 | 51 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_0500 | | biotin carboxyl carrier protein / biotin carboxylase | insig. | 40 | 50 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_0500 | | biotin carboxyl carrier protein / biotin carboxylase | insig. | 40 | 50 |
| | Klebsiella pneumoniae MRSN742743 | KFA93_RS24450 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | no data | 40 | 51 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_5061 | | acetyl-CoA carboxylase carboxyltransferase subunit alpha / biotin carboxylase | strong | 45 | 41 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_5061 | | acetyl-CoA carboxylase carboxyltransferase subunit alpha / biotin carboxylase | cofit | 45 | 41 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS09850 | | acetyl-CoA carboxylase biotin carboxylase subunit | insig. | 44 | 42 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS09850 | | acetyl-CoA carboxylase biotin carboxylase subunit | insig. | 44 | 42 |
| | Pseudomonas segetis P6 | ACVTMO_RS00855 | | acetyl-CoA carboxylase biotin carboxylase subunit | strong | 45 | 41 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS25460 | | acetyl-CoA carboxylase biotin carboxylase subunit | strong | 46 | 41 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_26245 | | acetyl-CoA carboxylase biotin carboxylase subunit | strong | 46 | 41 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS57910 | | acetyl-CoA carboxylase biotin carboxylase subunit | strong | 46 | 41 |
| | Pseudomonas orientalis W4I3 | QF045_RS02575 | | acetyl-CoA carboxylase biotin carboxylase subunit | strong | 45 | 41 |
| | Pseudomonas simiae WCS417 | PS417_28215 | | pyruvate carboxylase subunit A | no data | 45 | 41 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_4278 | | Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) | strong | 45 | 41 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS29880 | | acetyl-CoA carboxylase biotin carboxylase subunit | strong | 45 | 41 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS29880 | | acetyl-CoA carboxylase biotin carboxylase subunit | strong | 45 | 41 |
| | Pseudomonas sp. RS175 | PFR28_04518 | | 2-oxoglutarate carboxylase small subunit | strong | 45 | 41 |
| | Pseudomonas sp. SVBP6 | COO64_RS01815 | | acetyl-CoA carboxylase biotin carboxylase subunit | strong | 44 | 41 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_728 | | Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) | strong | 44 | 41 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_12020 | | pyruvate carboxylase subunit A | strong | 45 | 41 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_00111 | | 2-oxoglutarate carboxylase small subunit | strong | 45 | 41 |
| | Methylophilus sp. DMC18 | GFF2035 | | Biotin carboxylase | no data | 46 | 42 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_2010 | | Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) | strong | 44 | 41 |
| | Acinetobacter baumannii LAC-4 | RR41_RS10560 | | ATP-grasp domain-containing protein | insig. | 40 | 51 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_10030 | | pyruvate carboxylase subunit A | strong | 45 | 41 |
| | Pseudomonas sp. DMC3 | GFF507 | | 2-oxoglutarate carboxylase small subunit | strong | 44 | 41 |
| | Acinetobacter radioresistens SK82 | MPMX26_01369 | | Biotin carboxylase | no data | 42 | 42 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS01215 | | pyruvate carboxylase | insig. | 44 | 41 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_07595 | | acetyl-CoA carboxylase biotin carboxylase subunit | insig. | 44 | 41 |
| | Pseudomonas sp. S08-1 | OH686_13200 | | acetyl-CoA carboxylase, biotin carboxylase subunit | strong | 45 | 41 |
| | Rhizobium sp. OAE497 | ABIE40_RS07490 | | acetyl-CoA carboxylase biotin carboxylase subunit | no data | 44 | 42 |
| | Sinorhizobium meliloti 1021 | SMc03895 | | pyruvate carboxylase | strong | 43 | 41 |
| | Pseudomonas sp. BP01 | JOY50_RS08765 | | acetyl-CoA carboxylase biotin carboxylase subunit | strong | 44 | 41 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_28810 | | acetyl-CoA carboxylase biotin carboxylase subunit | insig. | 43 | 41 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_0191 | | acetyl-CoA carboxylase, biotin carboxylase subunit | no data | 43 | 41 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS07420 | | acetyl-CoA carboxylase biotin carboxylase subunit | strong | 41 | 42 |
| | Variovorax sp. SCN45 | GFF5548 | | Urea carboxylase (EC 6.3.4.6) without Allophanate hydrolase 2 domains | cofit | 41 | 51 |
| | Pseudomonas putida KT2440 | PP_5347 | | pyruvate carboxylase subunit A | strong | 44 | 41 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS00170 | | acetyl-CoA carboxylase biotin carboxylase subunit | no data | 44 | 41 |
| | Xanthobacter sp. DMC5 | GFF236 | | Biotin carboxylase | no data | 44 | 42 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS12680 | | acetyl-CoA carboxylase biotin carboxylase subunit | sig. | 41 | 42 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS15610 | | acetyl-CoA carboxylase biotin carboxylase subunit | insig. | 41 | 42 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_0292 | | acetyl-CoA carboxylase, biotin carboxylase subunit | no data | 44 | 41 |
| | Methylophilus sp. DMC18 | GFF1261 | | 2-oxoglutarate carboxylase small subunit | no data | 43 | 41 |
| | Agrobacterium fabrum C58 | Atu2726 | | pyruvate carboxylase | strong | 42 | 41 |
| | Dinoroseobacter shibae DFL-12 | Dshi_1395 | | acetyl-CoA carboxylase, biotin carboxylase (RefSeq) | no data | 44 | 42 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS36850 | | acetyl-CoA carboxylase biotin carboxylase subunit | insig. | 46 | 42 |
| | Pseudomonas sp. S08-1 | OH686_07595 | | acetyl-CoA carboxylase, biotin carboxylase subunit | no data | 44 | 42 |
| | Pseudomonas segetis P6 | ACVTMO_RS20345 | accC | acetyl-CoA carboxylase biotin carboxylase subunit | no data | 43 | 42 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS01450 | | acetyl-CoA carboxylase biotin carboxylase subunit | strong | 41 | 42 |
| | Sinorhizobium meliloti 1021 | SMc01345 | | acetyl-CoA carboxylase biotin carboxylase subunit | no data | 45 | 42 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c12600 | | biotin carboxylase AccA | no data | 41 | 42 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS22475 | | acetyl-CoA carboxylase biotin carboxylase subunit | insig. | 46 | 42 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_22955 | | acetyl-CoA carboxylase biotin carboxylase subunit | insig. | 46 | 42 |
| | Rhodopseudomonas palustris CGA009 | TX73_011060 | | acetyl-CoA carboxylase biotin carboxylase subunit | insig. | 45 | 42 |
| | Marinobacter adhaerens HP15 | HP15_3934 | | acetyl-CoA carboxylase biotin carboxylase subunit | insig. | 44 | 41 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c09420 | | pyruvate carboxylase Pyc | strong | 42 | 41 |
| | Cellulophaga baltica 18 | M666_RS04440 | | acetyl-CoA carboxylase biotin carboxylase subunit | no data | 41 | 41 |
| | Bifidobacterium breve UCC2003 | BBR_RS19380 | | ATP-grasp domain-containing protein | no data | 35 | 52 |
| | Dinoroseobacter shibae DFL-12 | Dshi_2485 | | pyruvate carboxylase (RefSeq) | strong | 42 | 41 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS18365 | | acetyl-CoA carboxylase biotin carboxylase subunit | no data | 42 | 41 |
| | Methanococcus maripaludis S2 | MMP_RS01825 | | acetyl-CoA carboxylase biotin carboxylase subunit | no data | 39 | 43 |
| | Pseudomonas stutzeri RCH2 | Psest_4085 | | Biotin carboxylase | strong | 44 | 41 |
| | Methanococcus maripaludis JJ | MMJJ_RS03555 | | acetyl-CoA carboxylase biotin carboxylase subunit | no data | 39 | 43 |
| | Marinobacter adhaerens HP15 | HP15_3149 | | urea amidolyase related protein | insig. | 42 | 41 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_08135 | | pyruvate carboxylase | insig. | 41 | 41 |
| | Rhodopseudomonas palustris CGA009 | TX73_012595 | | acetyl-CoA carboxylase biotin carboxylase subunit | no data | 44 | 42 |
| | Agrobacterium fabrum C58 | Atu1330 | | acetyl-CoA carboxylase, biotin carboxylase | no data | 44 | 42 |
| | Rhodospirillum rubrum S1H | Rru_A1121 | | Pyruvate carboxylase (NCBI) | strong | 44 | 41 |
| | Pseudomonas stutzeri RCH2 | Psest_1019 | | acetyl-CoA carboxylase, biotin carboxylase subunit | no data | 43 | 42 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_01465 | | acetyl-CoA carboxylase, biotin carboxylase subunit | sig. | 40 | 43 |
| | Castellaniella sp019104865 MT123 | ABCV34_RS10675 | | acetyl-CoA carboxylase biotin carboxylase subunit | no data | 43 | 42 |
| | Pseudomonas sp. BP01 | JOY50_RS12430 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | insig. | 42 | 42 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF587 | | Biotin carboxylase of acetyl-CoA carboxylase (EC 6.3.4.14) | no data | 43 | 42 |
| | Sphingobium sp. HT1-2 | GFF359 | | Biotin carboxylase of acetyl-CoA carboxylase (EC 6.3.4.14) | no data | 44 | 41 |
| | Pectobacterium carotovorum WPP14 | HER17_RS10230 | | urea carboxylase | cofit | 44 | 41 |
| | Bosea sp. OAE506 | ABIE41_RS16195 | | acetyl-CoA carboxylase biotin carboxylase subunit | no data | 43 | 42 |
| | Dechlorosoma suillum PS | Dsui_0389 | | acetyl-CoA carboxylase, biotin carboxylase subunit | no data | 43 | 42 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_4028 | | Biotin carboxylase of acetyl-CoA carboxylase (EC 6.3.4.14) | no data | 42 | 42 |