Conservation of cofitness between Psyr_4369 and Psyr_1257 in Pseudomonas syringae pv. syringae B728a

93 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas syringae pv. syringae B728a 1.0 Psyr_4369 glutamate-5-semialdehyde dehydrogenase 1.0 Psyr_1257 2-isopropylmalate synthase 0.86 15
Pseudomonas syringae pv. syringae B728a ΔmexB 1.00 Psyr_4369 glutamate-5-semialdehyde dehydrogenase 1.00 Psyr_1257 2-isopropylmalate synthase 0.95 3
Pseudomonas fluorescens FW300-N2E3 0.88 AO353_06495 gamma-glutamyl phosphate reductase 0.90 AO353_15925 2-isopropylmalate synthase 0.60 45
Pseudomonas fluorescens FW300-N2C3 0.88 AO356_15290 gamma-glutamyl phosphate reductase 0.92 AO356_06550 2-isopropylmalate synthase low > 104
Pseudomonas sp. RS175 0.87 PFR28_03872 Gamma-glutamyl phosphate reductase 0.92 PFR28_00305 2-isopropylmalate synthase
Pseudomonas fluorescens FW300-N1B4 0.86 Pf1N1B4_2688 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.90 Pf1N1B4_847 2-isopropylmalate synthase (EC 2.3.3.13) low > 87
Pseudomonas fluorescens FW300-N2E2 0.85 Pf6N2E2_4993 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.92 Pf6N2E2_3170 2-isopropylmalate synthase (EC 2.3.3.13) low > 103
Pseudomonas putida KT2440 0.85 PP_4811 Gamma-glutamyl phosphate reductase 0.91 PP_1025 2-isopropylmalate synthase low > 96
Pseudomonas fluorescens GW456-L13 0.85 PfGW456L13_1356 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.90 PfGW456L13_4854 2-isopropylmalate synthase (EC 2.3.3.13) low > 87
Pseudomonas fluorescens SBW25-INTG 0.75 PFLU_RS26675 glutamate-5-semialdehyde dehydrogenase 0.90 PFLU_RS24765 2-isopropylmalate synthase
Pseudomonas fluorescens SBW25 0.75 PFLU_RS26675 glutamate-5-semialdehyde dehydrogenase 0.90 PFLU_RS24765 2-isopropylmalate synthase
Pseudomonas simiae WCS417 0.75 PS417_24745 gamma-glutamyl phosphate reductase 0.90 PS417_23110 2-isopropylmalate synthase 0.62 28
Pseudomonas stutzeri RCH2 0.73 Psest_0508 gamma-glutamyl phosphate reductase 0.83 Psest_1277 2-isopropylmalate synthase, yeast type 0.63 37
Pseudomonas sp. S08-1 0.72 OH686_09340 Gamma-glutamyl phosphate reductase 0.78 OH686_17570 2-isopropylmalate synthase low > 80
Marinobacter adhaerens HP15 0.70 HP15_601 gamma-glutamyl phosphate reductase 0.52 HP15_2055 2-isopropylmalate synthase
Acinetobacter radioresistens SK82 0.67 MPMX26_00417 Gamma-glutamyl phosphate reductase 0.61 MPMX26_00404 2-isopropylmalate synthase low > 36
Ralstonia sp. UNC404CL21Col 0.61 ABZR87_RS01395 glutamate-5-semialdehyde dehydrogenase 0.62 ABZR87_RS22365 2-isopropylmalate synthase low > 80
Paraburkholderia sabiae LMG 24235 0.60 QEN71_RS26940 glutamate-5-semialdehyde dehydrogenase 0.58 QEN71_RS01640 2-isopropylmalate synthase low > 153
Dechlorosoma suillum PS 0.60 Dsui_1220 gamma-glutamyl phosphate reductase 0.60 Dsui_3227 2-isopropylmalate synthase
Ralstonia solanacearum UW163 0.60 UW163_RS07800 glutamate-5-semialdehyde dehydrogenase 0.64 UW163_RS17345 2-isopropylmalate synthase
Ralstonia solanacearum IBSBF1503 0.60 RALBFv3_RS05825 glutamate-5-semialdehyde dehydrogenase 0.64 RALBFv3_RS21840 2-isopropylmalate synthase low > 76
Ralstonia solanacearum PSI07 0.60 RPSI07_RS11475 glutamate-5-semialdehyde dehydrogenase 0.63 RPSI07_RS01320 2-isopropylmalate synthase low > 81
Ralstonia solanacearum GMI1000 0.59 RS_RS13715 gamma-glutamyl-phosphate reductase 0.62 RS_RS18695 2-isopropylmalate synthase 2
Herbaspirillum seropedicae SmR1 0.59 HSERO_RS02965 gamma-glutamyl phosphate reductase 0.66 HSERO_RS17185 2-isopropylmalate synthase low > 78
Castellaniella sp019104865 MT123 0.58 ABCV34_RS00845 glutamate-5-semialdehyde dehydrogenase 0.61 ABCV34_RS12420 2-isopropylmalate synthase
Paraburkholderia bryophila 376MFSha3.1 0.57 H281DRAFT_06324 glutamate-5-semialdehyde dehydrogenase 0.63 H281DRAFT_00385 2-isopropylmalate synthase low > 103
Burkholderia phytofirmans PsJN 0.57 BPHYT_RS16770 gamma-glutamyl phosphate reductase 0.64 BPHYT_RS13280 2-isopropylmalate synthase
Acidovorax sp. GW101-3H11 0.57 Ac3H11_704 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.55 Ac3H11_5000 2-isopropylmalate synthase (EC 2.3.3.13) low > 79
Cupriavidus basilensis FW507-4G11 0.56 RR42_RS17530 gamma-glutamyl phosphate reductase 0.62 RR42_RS21205 2-isopropylmalate synthase low > 128
Variovorax sp. SCN45 0.56 GFF6326 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.60 GFF1164 2-isopropylmalate synthase (EC 2.3.3.13) 0.88 57
Hydrogenophaga sp. GW460-11-11-14-LB1 0.55 GFF2641 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.62 GFF4280 2-isopropylmalate synthase (EC 2.3.3.13) low > 90
Paraburkholderia graminis OAS925 0.55 ABIE53_003523 glutamate-5-semialdehyde dehydrogenase 0.63 ABIE53_002867 2-isopropylmalate synthase low > 113
Variovorax sp. OAS795 0.54 ABID97_RS04600 glutamate-5-semialdehyde dehydrogenase 0.60 ABID97_RS14905 2-isopropylmalate synthase
Magnetospirillum magneticum AMB-1 0.50 AMB_RS20640 glutamate-5-semialdehyde dehydrogenase 0.56 AMB_RS17550 2-isopropylmalate synthase
Rhodospirillum rubrum S1H 0.49 Rru_A1238 Gamma-glutamyl phosphate reductase GPR (NCBI) 0.57 Rru_A1928 Yeast 2-isopropylmalate synthase (NCBI)
Azospirillum sp. SherDot2 0.48 MPMX19_01943 Gamma-glutamyl phosphate reductase 0.57 MPMX19_01822 2-isopropylmalate synthase
Agrobacterium fabrum C58 0.48 Atu2779 gamma-glutamyl phosphate reductase 0.54 Atu2264 2-isopropylmalate synthase
Sinorhizobium meliloti 1021 0.48 SMc03777 gamma-glutamyl phosphate reductase 0.53 SMc02717 2-isopropylmalate synthase 0.92 11
Azospirillum brasilense Sp245 0.46 AZOBR_RS04075 gamma-glutamyl phosphate reductase 0.57 AZOBR_RS12155 2-isopropylmalate synthase
Rhizobium sp. OAE497 0.46 ABIE40_RS18925 glutamate-5-semialdehyde dehydrogenase 0.50 ABIE40_RS13330 2-isopropylmalate synthase 0.93 10
Dinoroseobacter shibae DFL-12 0.46 Dshi_1469 gamma-glutamyl phosphate reductase (RefSeq) 0.10 Dshi_0596 2-isopropylmalate synthase (RefSeq)
Sphingomonas koreensis DSMZ 15582 0.46 Ga0059261_2506 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) 0.59 Ga0059261_4031 2-isopropylmalate synthase, yeast type 0.97 9
Rhodopseudomonas palustris CGA009 0.45 TX73_000855 glutamate-5-semialdehyde dehydrogenase 0.58 TX73_024250 2-isopropylmalate synthase
Caulobacter crescentus NA1000 Δfur 0.45 CCNA_03543 gamma-glutamyl phosphate reductase 0.10 CCNA_01610 2-isopropylmalate synthase low > 67
Caulobacter crescentus NA1000 0.45 CCNA_03543 gamma-glutamyl phosphate reductase 0.10 CCNA_01610 2-isopropylmalate synthase 0.85 51
Rhodanobacter denitrificans MT42 0.44 LRK55_RS02125 glutamate-5-semialdehyde dehydrogenase 0.09 LRK55_RS09985 2-isopropylmalate synthase low > 63
Rhodanobacter denitrificans FW104-10B01 0.44 LRK54_RS02370 glutamate-5-semialdehyde dehydrogenase 0.09 LRK54_RS10345 2-isopropylmalate synthase 0.89 8
Alteromonas macleodii MIT1002 0.44 MIT1002_01885 Gamma-glutamyl phosphate reductase 0.10 MIT1002_00949 2-isopropylmalate synthase 0.98 18
Lysobacter sp. OAE881 0.44 ABIE51_RS13365 glutamate-5-semialdehyde dehydrogenase 0.10 ABIE51_RS17570 2-isopropylmalate synthase low > 62
Dyella japonica UNC79MFTsu3.2 0.44 ABZR86_RS08680 glutamate-5-semialdehyde dehydrogenase 0.09 ABZR86_RS15970 2-isopropylmalate synthase 0.86 41
Klebsiella michiganensis M5al 0.44 BWI76_RS05835 gamma-glutamyl-phosphate reductase 0.55 BWI76_RS22105 2-isopropylmalate synthase low > 92
Escherichia coli Nissle 1917 0.44 ECOLIN_RS01830 glutamate-5-semialdehyde dehydrogenase 0.09 ECOLIN_RS00400 2-isopropylmalate synthase 0.95 6
Phaeobacter inhibens DSM 17395 0.44 PGA1_c15520 gamma-glutamyl phosphate reductase ProA 0.10 PGA1_c26470 2-isopropylmalate synthase LeuA 0.85 4
Escherichia coli ECOR38 0.43 HEPCGN_07775 proA glutamate-5-semialdehyde dehydrogenase 0.09 HEPCGN_08695 2-isopropylmalate synthase 0.93 21
Escherichia coli ECRC101 0.43 MCAODC_00190 proA glutamate-5-semialdehyde dehydrogenase 0.09 MCAODC_01230 2-isopropylmalate synthase 0.94 16
Escherichia coli BL21 0.43 ECD_00240 gamma-glutamylphosphate reductase 0.09 ECD_00076 2-isopropylmalate synthase 0.93 5
Escherichia coli ECRC100 0.43 OKFHMN_09670 proA glutamate-5-semialdehyde dehydrogenase 0.09 OKFHMN_10715 2-isopropylmalate synthase 0.96 28
Escherichia coli ECOR27 0.43 NOLOHH_02045 proA glutamate-5-semialdehyde dehydrogenase 0.09 NOLOHH_03060 2-isopropylmalate synthase 0.98 4
Escherichia coli ECRC102 0.43 NIAGMN_07530 proA glutamate-5-semialdehyde dehydrogenase 0.09 NIAGMN_08565 2-isopropylmalate synthase
Escherichia coli HS(pFamp)R (ATCC 700891) 0.43 OHPLBJKB_03397 Gamma-glutamyl phosphate reductase 0.09 OHPLBJKB_03583 2-isopropylmalate synthase low > 73
Escherichia coli ECRC62 0.43 BNILDI_00240 proA glutamate-5-semialdehyde dehydrogenase 0.09 BNILDI_08550 2-isopropylmalate synthase 0.95 33
Escherichia coli ECRC98 0.43 JDDGAC_13295 proA glutamate-5-semialdehyde dehydrogenase 0.09 JDDGAC_14310 2-isopropylmalate synthase 0.87 33
Escherichia coli ECRC99 0.43 KEDOAH_18485 proA glutamate-5-semialdehyde dehydrogenase 0.09 KEDOAH_17440 2-isopropylmalate synthase
Escherichia fergusonii Becca 0.43 EFB2_03777 Gamma-glutamyl phosphate reductase 0.09 EFB2_03971 2-isopropylmalate synthase low > 86
Escherichia coli BW25113 0.43 b0243 proA gamma-glutamyl phosphate reductase (NCBI) 0.09 b0074 leuA 2-isopropylmalate synthase (NCBI) 0.94 5
Enterobacter sp. TBS_079 0.43 MPMX20_00928 Gamma-glutamyl phosphate reductase 0.55 MPMX20_03565 2-isopropylmalate synthase low > 85
Enterobacter asburiae PDN3 0.43 EX28DRAFT_2650 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) 0.57 EX28DRAFT_2770 2-isopropylmalate synthase, yeast type low > 76
Dickeya dadantii 3937 0.43 DDA3937_RS16530 glutamate-5-semialdehyde dehydrogenase 0.51 DDA3937_RS02895 2-isopropylmalate synthase low > 74
Shewanella sp. ANA-3 0.43 Shewana3_4057 glutamate-5-semialdehyde dehydrogenase (RefSeq) 0.10 Shewana3_3761 2-isopropylmalate synthase (RefSeq) low > 73
Shewanella loihica PV-4 0.43 Shew_3015 gamma-glutamyl phosphate reductase (RefSeq) 0.09 Shew_3472 2-isopropylmalate synthase (RefSeq) low > 60
Desulfovibrio vulgaris Hildenborough JW710 0.43 DVU1953 proA gamma-glutamyl phosphate reductase (TIGR) 0.12 DVU2981 leuA 2-isopropylmalate synthase (TIGR) 0.84 20
Rahnella sp. WP5 0.43 EX31_RS20975 glutamate-5-semialdehyde dehydrogenase 0.58 EX31_RS24130 2-isopropylmalate synthase low > 89
Dickeya dianthicola ME23 0.42 DZA65_RS17690 glutamate-5-semialdehyde dehydrogenase 0.11 DZA65_RS19200 2-isopropylmalate synthase low > 75
Serratia liquefaciens MT49 0.42 IAI46_04435 glutamate-5-semialdehyde dehydrogenase 0.58 IAI46_09630 2-isopropylmalate synthase low > 86
Pantoea sp. MT58 0.41 IAI47_15115 glutamate-5-semialdehyde dehydrogenase 0.52 IAI47_10235 2-isopropylmalate synthase low > 76
Rhodanobacter sp. FW510-T8 0.41 OKGIIK_09415 proA glutamate-5-semialdehyde dehydrogenase 0.09 OKGIIK_13575 leuA 2-isopropylmalate synthase low > 52
Xanthomonas campestris pv. campestris strain 8004 0.41 Xcc-8004.2327.1 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.09 Xcc-8004.1056.1 2-isopropylmalate synthase (EC 2.3.3.13) low > 74
Erwinia tracheiphila SCR3 0.40 LU632_RS01190 proA glutamate-5-semialdehyde dehydrogenase 0.10 LU632_RS02880 leuA 2-isopropylmalate synthase 0.67 49
Bosea sp. OAE506 0.40 ABIE41_RS07580 glutamate-5-semialdehyde dehydrogenase 0.11 ABIE41_RS13000 2-isopropylmalate synthase
Desulfovibrio vulgaris Miyazaki F 0.40 DvMF_0612 proA gamma-glutamyl phosphate reductase (RefSeq) 0.13 DvMF_1791 2-isopropylmalate synthase (RefSeq) 0.90 22
Mycobacterium tuberculosis H37Rv 0.40 Rv2427c Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialdehyde dehydrogenase) 0.53 Rv3710 2-isopropylmalate synthase LeuA (alpha-isopropylmalate synthase) (alpha-IPM synthetase) (IPMS)
Bifidobacterium breve UCC2003 0.40 BBR_RS14075 glutamate-5-semialdehyde dehydrogenase 0.48 BBR_RS11170 2-isopropylmalate synthase low > 34
Dickeya dianthicola 67-19 0.40 HGI48_RS16600 glutamate-5-semialdehyde dehydrogenase 0.10 HGI48_RS18055 2-isopropylmalate synthase 0.81 22
Pectobacterium carotovorum WPP14 0.40 HER17_RS04705 glutamate-5-semialdehyde dehydrogenase 0.09 HER17_RS03085 2-isopropylmalate synthase 0.97 8
Shewanella oneidensis MR-1 0.39 SO1122 proA gamma-glutamyl phosphate reductase (NCBI ptt file) 0.10 SO4236 leuA 2-isopropylmalate synthase (NCBI ptt file) 0.98 13
Vibrio cholerae E7946 ATCC 55056 0.39 CSW01_11570 glutamate-5-semialdehyde dehydrogenase 0.10 CSW01_12595 2-isopropylmalate synthase low > 62
Shewanella amazonensis SB2B 0.37 Sama_2515 proA gamma-glutamyl phosphate reductase (RefSeq) 0.10 Sama_0335 2-isopropylmalate synthase (RefSeq) 0.93 37
Synechococcus elongatus PCC 7942 0.36 Synpcc7942_2265 proA glutamate-5-semialdehyde dehydrogenase 0.09 Synpcc7942_1410 leuA 2-isopropylmalate synthase
Bacteroides stercoris CC31F 0.36 HMPREF1181_RS03320 glutamate-5-semialdehyde dehydrogenase 0.11 HMPREF1181_RS14150 2-isopropylmalate synthase 0.91 31
Parabacteroides merdae CL09T00C40 0.35 HMPREF1078_RS10655 glutamate-5-semialdehyde dehydrogenase 0.12 HMPREF1078_RS16665 2-isopropylmalate synthase 0.91 50
Bacteroides thetaiotaomicron VPI-5482 0.34 BT3718 gamma-glutamyl phosphate reductase (NCBI ptt file) 0.10 BT1861 2-isopropylmalate synthase (EC 2.3.3.13) (from data) 0.96 2
Phocaeicola dorei CL03T12C01 0.33 ABI39_RS02875 glutamate-5-semialdehyde dehydrogenase 0.11 ABI39_RS10195 2-isopropylmalate synthase 0.80 35
Phocaeicola vulgatus CL09T03C04 0.33 HMPREF1058_RS08645 glutamate-5-semialdehyde dehydrogenase 0.11 HMPREF1058_RS14545 2-isopropylmalate synthase 0.93 15
Bacteroides ovatus ATCC 8483 0.32 BACOVA_03534 glutamate-5-semialdehyde dehydrogenase 0.10 BACOVA_04604 2-isopropylmalate synthase 0.96 21

Not shown: 7 genomes with orthologs for Psyr_4369 only; 2 genomes with orthologs for Psyr_1257 only