Conservation of cofitness between PP_1988 and PP_0421 in Pseudomonas putida KT2440

82 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_1988 3-isopropylmalate dehydrogenase 1.0 PP_0421 Anthranilate phosphoribosyltransferase 0.91 10
Pseudomonas fluorescens FW300-N2E2 0.94 Pf6N2E2_66 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.87 Pf6N2E2_4825 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) 0.93 11
Pseudomonas fluorescens FW300-N2C3 0.94 AO356_21415 3-isopropylmalate dehydrogenase 0.87 AO356_14435 anthranilate phosphoribosyltransferase 0.93 14
Pseudomonas fluorescens GW456-L13 0.93 PfGW456L13_3945 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.85 PfGW456L13_1221 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) 0.88 33
Pseudomonas fluorescens SBW25 0.93 PFLU_RS20565 3-isopropylmalate dehydrogenase 0.87 PFLU_RS27370 anthranilate phosphoribosyltransferase 0.85 4
Pseudomonas simiae WCS417 0.93 PS417_18585 3-isopropylmalate dehydrogenase 0.87 PS417_25715 anthranilate phosphoribosyltransferase 0.85 22
Pseudomonas fluorescens SBW25-INTG 0.93 PFLU_RS20565 3-isopropylmalate dehydrogenase 0.87 PFLU_RS27370 anthranilate phosphoribosyltransferase 0.86 8
Pseudomonas fluorescens FW300-N1B4 0.93 Pf1N1B4_12 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.87 Pf1N1B4_2548 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) 0.88 13
Pseudomonas sp. RS175 0.93 PFR28_02821 3-isopropylmalate dehydrogenase 0.87 PFR28_04044 Anthranilate phosphoribosyltransferase — —
Pseudomonas fluorescens FW300-N2E3 0.92 AO353_20635 3-isopropylmalate dehydrogenase 0.88 AO353_07215 anthranilate phosphoribosyltransferase 0.93 12
Pseudomonas syringae pv. syringae B728a 0.91 Psyr_1985 3-isopropylmalate dehydrogenase 0.90 Psyr_4580 anthranilate phosphoribosyltransferase 0.75 33
Pseudomonas syringae pv. syringae B728a ΔmexB 0.91 Psyr_1985 3-isopropylmalate dehydrogenase 0.90 Psyr_4580 anthranilate phosphoribosyltransferase 0.73 58
Pseudomonas stutzeri RCH2 0.87 Psest_2589 3-isopropylmalate dehydrogenase 0.77 Psest_3648 anthranilate phosphoribosyltransferase 0.80 23
Pseudomonas sp. S08-1 0.87 OH686_04470 3-isopropylmalate dehydrogenase 0.75 OH686_15135 Anthranilate phosphoribosyltransferase 0.67 43
Xanthomonas campestris pv. campestris strain 8004 0.81 Xcc-8004.1053.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.38 Xcc-8004.621.1 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) 0.97 3
Acinetobacter radioresistens SK82 0.73 MPMX26_00348 3-isopropylmalate dehydrogenase 0.60 MPMX26_00984 Anthranilate phosphoribosyltransferase 0.94 12
Marinobacter adhaerens HP15 0.73 HP15_1832 3-isopropylmalate dehydrogenase 0.58 HP15_3290 anthranilate phosphoribosyltransferase 0.78 26
Kangiella aquimarina DSM 16071 0.70 B158DRAFT_1322 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.29 B158DRAFT_2427 anthranilate phosphoribosyltransferase low > 40
Dechlorosoma suillum PS 0.68 Dsui_3198 3-isopropylmalate dehydrogenase 0.44 Dsui_0169 anthranilate phosphoribosyltransferase — —
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS14530 3-isopropylmalate dehydrogenase 0.42 ABZR87_RS02155 anthranilate phosphoribosyltransferase 0.90 13
Paraburkholderia bryophila 376MFSha3.1 0.65 H281DRAFT_06072 3-isopropylmalate dehydrogenase 0.45 H281DRAFT_05713 anthranilate phosphoribosyltransferase 0.67 13
Paraburkholderia graminis OAS925 0.65 ABIE53_004804 3-isopropylmalate dehydrogenase 0.44 ABIE53_003642 anthranilate phosphoribosyltransferase — —
Herbaspirillum seropedicae SmR1 0.65 HSERO_RS16500 3-isopropylmalate dehydrogenase 0.37 HSERO_RS19445 anthranilate phosphoribosyltransferase 0.90 13
Cupriavidus basilensis FW507-4G11 0.64 RR42_RS14385 3-isopropylmalate dehydrogenase 0.45 RR42_RS18305 anthranilate phosphoribosyltransferase 0.74 25
Variovorax sp. OAS795 0.64 ABID97_RS08455 3-isopropylmalate dehydrogenase 0.44 ABID97_RS05275 anthranilate phosphoribosyltransferase — —
Ralstonia solanacearum GMI1000 0.64 RS_RS09990 3-isopropylmalate dehydrogenase 0.42 RS_RS14445 Anthranilate phosphoribosyltransferase 1 0.52 17
Ralstonia solanacearum UW163 0.64 UW163_RS11115 3-isopropylmalate dehydrogenase 0.42 UW163_RS07125 anthranilate phosphoribosyltransferase — —
Ralstonia solanacearum IBSBF1503 0.64 RALBFv3_RS02610 3-isopropylmalate dehydrogenase 0.42 RALBFv3_RS06500 anthranilate phosphoribosyltransferase — —
Variovorax sp. SCN45 0.64 GFF3888 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.43 GFF5891 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) — —
Burkholderia phytofirmans PsJN 0.64 BPHYT_RS33900 3-isopropylmalate dehydrogenase 0.44 BPHYT_RS17400 anthranilate phosphoribosyltransferase 0.93 9
Acidovorax sp. GW101-3H11 0.64 Ac3H11_1528 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.43 Ac3H11_771 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) 0.92 9
Paraburkholderia sabiae LMG 24235 0.63 QEN71_RS17620 3-isopropylmalate dehydrogenase 0.44 QEN71_RS27560 anthranilate phosphoribosyltransferase 0.71 41
Ralstonia solanacearum PSI07 0.63 RPSI07_RS14705 3-isopropylmalate dehydrogenase 0.42 RPSI07_RS10740 anthranilate phosphoribosyltransferase — —
Castellaniella sp019104865 MT123 0.63 ABCV34_RS04280 3-isopropylmalate dehydrogenase 0.40 ABCV34_RS10305 anthranilate phosphoribosyltransferase low > 48
Hydrogenophaga sp. GW460-11-11-14-LB1 0.63 GFF3360 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.45 GFF3110 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) 0.77 22
Desulfovibrio vulgaris Miyazaki F 0.61 DvMF_1794 3-isopropylmalate dehydrogenase (RefSeq) 0.25 DvMF_1744 anthranilate phosphoribosyltransferase (RefSeq) 0.89 24
Phaeobacter inhibens DSM 17395 0.60 PGA1_c29830 3-isopropylmalate dehydrogenase LeuB 0.31 PGA1_c16890 anthranilate phosphoribosyltransferase TrpD — —
Rhizobium sp. OAE497 0.58 ABIE40_RS19050 3-isopropylmalate dehydrogenase 0.39 ABIE40_RS09545 anthranilate phosphoribosyltransferase low > 107
Dinoroseobacter shibae DFL-12 0.58 Dshi_0081 3-isopropylmalate dehydrogenase (RefSeq) 0.31 Dshi_1799 anthranilate phosphoribosyltransferase (RefSeq) — —
Sinorhizobium meliloti 1021 0.58 SMc04405 3-isopropylmalate dehydrogenase 0.39 SMc00235 anthranilate phosphoribosyltransferase 0.73 77
Synechococcus elongatus PCC 7942 0.58 Synpcc7942_1505 leuB 3-isopropylmalate dehydrogenase 0.26 Synpcc7942_2123 trpD anthranilate phosphoribosyltransferase — —
Desulfovibrio vulgaris Hildenborough JW710 0.57 DVU2985 leuB 3-isopropylmalate dehydrogenase (TIGR) 0.26 DVU0467 trpD anthranilate phosphoribosyltransferase (TIGR) 0.82 39
Azospirillum sp. SherDot2 0.57 MPMX19_00607 3-isopropylmalate dehydrogenase 0.35 MPMX19_01015 Anthranilate phosphoribosyltransferase 0.82 21
Agrobacterium fabrum C58 0.57 Atu2791 3-isopropylmalate dehydrogenase 0.37 Atu1687 anthranilate phosphoribosyltransferase 0.91 15
Magnetospirillum magneticum AMB-1 0.56 AMB_RS20570 3-isopropylmalate dehydrogenase 0.36 AMB_RS14410 anthranilate phosphoribosyltransferase — —
Rhodospirillum rubrum S1H 0.56 Rru_A1191 3-isopropylmalate dehydrogenase (NCBI) 0.36 Rru_A1896 Anthranilate phosphoribosyl transferase (NCBI) 0.89 13
Sphingomonas koreensis DSMZ 15582 0.56 Ga0059261_3190 3-isopropylmalate dehydrogenase 0.22 Ga0059261_0929 anthranilate phosphoribosyltransferase 0.93 43
Azospirillum brasilense Sp245 0.55 AZOBR_RS14130 3-isopropylmalate dehydrogenase 0.36 AZOBR_RS07455 anthranilate phosphoribosyltransferase 0.72 26
Serratia liquefaciens MT49 0.53 IAI46_03350 3-isopropylmalate dehydrogenase 0.26 IAI46_14030 anthranilate phosphoribosyltransferase low > 86
Shewanella loihica PV-4 0.53 Shew_3471 3-isopropylmalate dehydrogenase (RefSeq) 0.29 Shew_2253 anthranilate phosphoribosyltransferase (RefSeq) 0.93 39
Rahnella sp. WP5 0.53 EX31_RS03685 3-isopropylmalate dehydrogenase 0.27 EX31_RS09965 anthranilate phosphoribosyltransferase 0.96 37
Rhodopseudomonas palustris CGA009 0.53 TX73_001175 3-isopropylmalate dehydrogenase 0.41 TX73_014980 anthranilate phosphoribosyltransferase — —
Bosea sp. OAE506 0.53 ABIE41_RS11860 3-isopropylmalate dehydrogenase 0.36 ABIE41_RS17420 anthranilate phosphoribosyltransferase — —
Shewanella sp. ANA-3 0.53 Shewana3_3760 3-isopropylmalate dehydrogenase (RefSeq) 0.28 Shewana3_1518 trpD anthranilate phosphoribosyltransferase (RefSeq) 0.91 33
Shewanella oneidensis MR-1 0.53 SO4235 leuB 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.27 SO3021 trpD anthranilate phosphoribosyltransferase (NCBI ptt file) 0.90 54
Vibrio cholerae E7946 ATCC 55056 0.53 CSW01_12600 3-isopropylmalate dehydrogenase 0.29 CSW01_05940 anthranilate phosphoribosyltransferase low > 62
Shewanella amazonensis SB2B 0.52 Sama_0336 3-isopropylmalate dehydrogenase (RefSeq) 0.33 Sama_2131 trpD anthranilate phosphoribosyltransferase (RefSeq) 0.89 56
Dickeya dianthicola ME23 0.52 DZA65_RS19205 3-isopropylmalate dehydrogenase 0.28 DZA65_RS10955 anthranilate phosphoribosyltransferase low > 75
Dickeya dadantii 3937 0.52 DDA3937_RS18120 3-isopropylmalate dehydrogenase 0.29 DDA3937_RS10475 anthranilate phosphoribosyltransferase 0.62 66
Dickeya dianthicola 67-19 0.52 HGI48_RS18060 3-isopropylmalate dehydrogenase 0.28 HGI48_RS10475 anthranilate phosphoribosyltransferase low > 71
Caulobacter crescentus NA1000 0.51 CCNA_00193 3-isopropylmalate dehydrogenase 0.29 CCNA_01975 anthranilate phosphoribosyltransferase 0.91 35
Caulobacter crescentus NA1000 Δfur 0.51 CCNA_00193 3-isopropylmalate dehydrogenase 0.29 CCNA_01975 anthranilate phosphoribosyltransferase low > 67
Alteromonas macleodii MIT1002 0.51 MIT1002_00948 3-isopropylmalate dehydrogenase 0.31 MIT1002_01428 Anthranilate synthase component II 0.91 47
Pantoea sp. MT58 0.50 IAI47_16005 3-isopropylmalate dehydrogenase 0.26 IAI47_09180 anthranilate phosphoribosyltransferase 0.96 24
Lysobacter sp. OAE881 0.49 ABIE51_RS17585 3-isopropylmalate dehydrogenase 0.39 ABIE51_RS04180 anthranilate phosphoribosyltransferase low > 62
Pedobacter sp. GW460-11-11-14-LB5 0.49 CA265_RS15850 3-isopropylmalate dehydrogenase 0.23 CA265_RS05010 anthranilate phosphoribosyltransferase (EC 2.4.2.18) (from data) 0.72 64
Echinicola vietnamensis KMM 6221, DSM 17526 0.46 Echvi_2062 3-isopropylmalate dehydrogenase 0.25 Echvi_2507 anthranilate phosphoribosyltransferase — —
Rhodanobacter denitrificans FW104-10B01 0.45 LRK54_RS10325 3-isopropylmalate dehydrogenase 0.41 LRK54_RS11565 anthranilate phosphoribosyltransferase low > 59
Rhodanobacter denitrificans MT42 0.45 LRK55_RS09965 3-isopropylmalate dehydrogenase 0.41 LRK55_RS11295 anthranilate phosphoribosyltransferase low > 63
Parabacteroides merdae CL09T00C40 0.45 HMPREF1078_RS16640 3-isopropylmalate dehydrogenase 0.23 HMPREF1078_RS00135 anthranilate phosphoribosyltransferase 0.93 34
Rhodanobacter sp. FW510-T8 0.45 OKGIIK_13595 leuB 3-isopropylmalate dehydrogenase 0.40 OKGIIK_12285 trpD anthranilate phosphoribosyltransferase low > 52
Bacteroides stercoris CC31F 0.44 HMPREF1181_RS14125 3-isopropylmalate dehydrogenase 0.24 HMPREF1181_RS15335 anthranilate phosphoribosyltransferase 0.85 43
Brevundimonas sp. GW460-12-10-14-LB2 0.43 A4249_RS09995 3-isopropylmalate dehydrogenase 0.29 A4249_RS06170 anthranilate phosphoribosyltransferase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.43 CA264_09445 3-isopropylmalate dehydrogenase 0.24 CA264_05065 anthranilate phosphoribosyltransferase low > 74
Bacteroides thetaiotaomicron VPI-5482 0.43 BT1857 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.23 BT0530 anthranilate phosphoribosyltransferase (EC 2.4.2.18) (from data) 0.83 33
Phocaeicola vulgatus CL09T03C04 0.43 HMPREF1058_RS14565 3-isopropylmalate dehydrogenase 0.23 HMPREF1058_RS07185 anthranilate phosphoribosyltransferase 0.82 9
Phocaeicola dorei CL03T12C01 0.43 ABI39_RS10215 3-isopropylmalate dehydrogenase 0.24 ABI39_RS21060 anthranilate phosphoribosyltransferase 0.75 44
Bacteroides ovatus ATCC 8483 0.42 BACOVA_04600 3-isopropylmalate dehydrogenase 0.23 BACOVA_03782 anthranilate phosphoribosyltransferase 0.92 45
Dyella japonica UNC79MFTsu3.2 0.42 ABZR86_RS15950 3-isopropylmalate dehydrogenase 0.43 ABZR86_RS12070 anthranilate phosphoribosyltransferase 0.89 62
Methanococcus maripaludis JJ 0.29 MMJJ_RS02220 3-isopropylmalate dehydrogenase 0.27 MMJJ_RS09170 anthranilate phosphoribosyltransferase — —
Methanococcus maripaludis S2 0.28 MMP_RS02855 3-isopropylmalate dehydrogenase 0.27 MMP_RS05210 anthranilate phosphoribosyltransferase — —
Mycobacterium tuberculosis H37Rv 0.27 Rv2995c Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) 0.24 Rv2192c Probable anthranilate phosphoribosyltransferase TrpD — —
Bifidobacterium breve UCC2003 0.25 BBR_RS12870 3-isopropylmalate dehydrogenase 0.23 BBR_RS16510 anthranilate phosphoribosyltransferase low > 34

Not shown: 20 genomes with orthologs for PP_1988 only; 0 genomes with orthologs for PP_0421 only