Conservation of cofitness between HER17_RS04700 and HER17_RS12230 in Pectobacterium carotovorum WPP14

98 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS04700 glutamate 5-kinase 1.0 HER17_RS12230 histidinol dehydrogenase 0.91 20
Rahnella sp. WP5 0.90 EX31_RS20980 glutamate 5-kinase 0.81 EX31_RS11440 histidinol dehydrogenase 0.94 38
Serratia liquefaciens MT49 0.90 IAI46_04430 glutamate 5-kinase 0.82 IAI46_08210 histidinol dehydrogenase low > 86
Enterobacter sp. TBS_079 0.89 MPMX20_00927 Glutamate 5-kinase 0.79 MPMX20_03002 Histidinol dehydrogenase 0.93 9
Klebsiella michiganensis M5al 0.89 BWI76_RS05840 glutamate 5-kinase 0.79 BWI76_RS18925 histidinol dehydrogenase 0.87 28
Pantoea sp. MT58 0.89 IAI47_15120 glutamate 5-kinase 0.79 IAI47_07090 histidinol dehydrogenase 0.91 18
Enterobacter asburiae PDN3 0.89 EX28DRAFT_2651 glutamate 5-kinase 0.80 EX28DRAFT_0539 histidinol dehydrogenase 0.93 2
Dickeya dianthicola 67-19 0.89 HGI48_RS16605 glutamate 5-kinase 0.84 HGI48_RS09745 histidinol dehydrogenase low > 71
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.89 GFF4114 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.80 GFF3912 Histidinol dehydrogenase (EC 1.1.1.23) low > 78
Escherichia coli ECRC100 0.88 OKFHMN_09675 proB Glutamate 5-kinase 0.80 OKFHMN_24515 hisD Histidinol dehydrogenase 0.87 62
Escherichia fergusonii Becca 0.88 EFB2_03778 Glutamate 5-kinase 0.81 EFB2_01836 Histidinol dehydrogenase low > 86
Escherichia coli Nissle 1917 0.88 ECOLIN_RS01825 glutamate 5-kinase 0.81 ECOLIN_RS11945 histidinol dehydrogenase — —
Escherichia coli ECRC62 0.88 BNILDI_00245 proB Glutamate 5-kinase 0.80 BNILDI_14740 hisD Histidinol dehydrogenase 0.95 34
Escherichia coli ECOR38 0.88 HEPCGN_07780 proB Glutamate 5-kinase 0.81 HEPCGN_03220 hisD Histidinol dehydrogenase 0.95 16
Escherichia coli ECOR27 0.88 NOLOHH_02050 proB Glutamate 5-kinase 0.80 NOLOHH_15830 hisD Histidinol dehydrogenase 0.94 33
Escherichia coli ECRC98 0.88 JDDGAC_13300 proB Glutamate 5-kinase 0.80 JDDGAC_28625 hisD Histidinol dehydrogenase 0.85 33
Escherichia coli BL21 0.88 ECD_00239 gamma-glutamate kinase 0.81 ECD_01922 bifunctional histidinal dehydrogenase/ histidinol dehydrogenase 0.87 25
Escherichia coli ECRC101 0.88 MCAODC_00195 proB Glutamate 5-kinase 0.80 MCAODC_20425 hisD Histidinol dehydrogenase 0.86 35
Escherichia coli ECRC99 0.88 KEDOAH_18480 proB Glutamate 5-kinase 0.80 KEDOAH_03635 hisD Histidinol dehydrogenase — —
Dickeya dianthicola ME23 0.88 DZA65_RS17695 glutamate 5-kinase 0.83 DZA65_RS10055 histidinol dehydrogenase low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.88 OHPLBJKB_03398 Glutamate 5-kinase 0.80 OHPLBJKB_01680 Histidinol dehydrogenase low > 73
Escherichia coli ECRC102 0.88 NIAGMN_07535 proB Glutamate 5-kinase 0.80 NIAGMN_22460 hisD Histidinol dehydrogenase — —
Escherichia coli BW25113 0.88 b0242 proB gamma-glutamyl kinase (NCBI) 0.80 b2020 hisD histidinol dehydrogenase (NCBI) 0.94 10
Erwinia tracheiphila SCR3 0.88 LU632_RS01185 proB glutamate 5-kinase 0.75 LU632_RS08945 hisD histidinol dehydrogenase low > 74
Dickeya dadantii 3937 0.88 DDA3937_RS16535 glutamate 5-kinase 0.84 DDA3937_RS09735 histidinol dehydrogenase 0.82 9
Vibrio cholerae E7946 ATCC 55056 0.64 CSW01_11575 glutamate 5-kinase 0.63 CSW01_05750 histidinol dehydrogenase low > 62
Shewanella loihica PV-4 0.62 Shew_2848 gamma-glutamyl kinase (RefSeq) 0.55 Shew_2198 histidinol dehydrogenase (RefSeq) 0.92 39
Shewanella amazonensis SB2B 0.62 Sama_2516 gamma-glutamyl kinase (RefSeq) 0.54 Sama_1942 hisD histidinol dehydrogenase (RefSeq) 0.92 37
Shewanella sp. ANA-3 0.59 Shewana3_0954 gamma-glutamyl kinase (RefSeq) 0.54 Shewana3_1853 hisD histidinol dehydrogenase (RefSeq) 0.94 15
Shewanella oneidensis MR-1 0.59 SO1121 proB glutamate 5-kinase (NCBI ptt file) 0.53 SO2073 hisD histidinol dehydrogenase (NCBI ptt file) 0.98 4
Dechlorosoma suillum PS 0.40 Dsui_0166 glutamate 5-kinase 0.31 Dsui_1411 histidinol dehydrogenase — —
Pseudomonas fluorescens SBW25 0.39 PFLU_RS25360 glutamate 5-kinase 0.34 PFLU_RS04470 histidinol dehydrogenase 0.59 10
Pseudomonas fluorescens SBW25-INTG 0.39 PFLU_RS25360 glutamate 5-kinase 0.34 PFLU_RS04470 histidinol dehydrogenase 0.59 4
Pseudomonas simiae WCS417 0.39 PS417_23545 gamma-glutamyl kinase 0.34 PS417_04420 histidinol dehydrogenase 0.65 16
Pseudomonas fluorescens FW300-N1B4 0.39 Pf1N1B4_2800 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.33 Pf1N1B4_1066 Histidinol dehydrogenase (EC 1.1.1.23) — —
Pseudomonas fluorescens FW300-N2E3 0.37 AO353_14115 gamma-glutamyl kinase 0.33 AO353_05110 histidinol dehydrogenase 0.73 34
Pseudomonas syringae pv. syringae B728a 0.37 Psyr_0704 glutamate 5-kinase 0.33 Psyr_4133 histidinol dehydrogenase 0.84 16
Paraburkholderia graminis OAS925 0.37 ABIE53_003588 glutamate 5-kinase 0.29 ABIE53_003701 histidinol dehydrogenase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.37 Psyr_0704 glutamate 5-kinase 0.33 Psyr_4133 histidinol dehydrogenase 0.85 21
Pseudomonas fluorescens GW456-L13 0.37 PfGW456L13_1472 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.33 PfGW456L13_5000 Histidinol dehydrogenase (EC 1.1.1.23) 0.88 19
Burkholderia phytofirmans PsJN 0.37 BPHYT_RS17110 glutamate 5-kinase 0.30 BPHYT_RS17710 histidinol dehydrogenase — —
Paraburkholderia bryophila 376MFSha3.1 0.37 H281DRAFT_06264 glutamate 5-kinase 0.29 H281DRAFT_05652 histidinol dehydrogenase — —
Paraburkholderia sabiae LMG 24235 0.37 QEN71_RS27270 glutamate 5-kinase 0.29 QEN71_RS27865 histidinol dehydrogenase 0.88 40
Pseudomonas fluorescens FW300-N2E2 0.36 Pf6N2E2_5103 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.32 Pf6N2E2_3252 Histidinol dehydrogenase (EC 1.1.1.23) low > 103
Ralstonia solanacearum UW163 0.36 UW163_RS07480 glutamate 5-kinase 0.29 UW163_RS06770 histidinol dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.36 RALBFv3_RS06145 glutamate 5-kinase 0.29 RALBFv3_RS06845 histidinol dehydrogenase — —
Synechococcus elongatus PCC 7942 0.36 Synpcc7942_2197 proB gamma-glutamyl kinase 0.32 Synpcc7942_1519 hisD histidinol dehydrogenase — —
Pseudomonas fluorescens FW300-N2C3 0.36 AO356_15815 gamma-glutamyl kinase 0.33 AO356_06965 histidinol dehydrogenase 0.61 44
Pseudomonas putida KT2440 0.36 PP_0691 Glutamate 5-kinase 0.33 PP_0966 Histidinol dehydrogenase 0.39 24
Pseudomonas sp. RS175 0.36 PFR28_03769 Glutamate 5-kinase 0.32 PFR28_00187 Histidinol dehydrogenase — —
Variovorax sp. OAS795 0.36 ABID97_RS23400 glutamate 5-kinase 0.32 ABID97_RS23160 histidinol dehydrogenase — —
Herbaspirillum seropedicae SmR1 0.36 HSERO_RS01815 gamma-glutamyl kinase 0.31 HSERO_RS20345 histidinol dehydrogenase 0.83 20
Pseudomonas sp. S08-1 0.36 OH686_16305 Glutamate 5-kinase / RNA-binding C-terminal domain PUA 0.33 OH686_08470 Histidinol dehydrogenase 0.82 5
Azospirillum sp. SherDot2 0.36 MPMX19_01933 Glutamate 5-kinase 0.32 MPMX19_05543 Histidinol dehydrogenase — —
Cupriavidus basilensis FW507-4G11 0.36 RR42_RS17940 gamma-glutamyl kinase 0.32 RR42_RS18915 histidinol dehydrogenase — —
Ralstonia solanacearum PSI07 0.35 RPSI07_RS11095 glutamate 5-kinase 0.29 RPSI07_RS10390 histidinol dehydrogenase — —
Ralstonia solanacearum GMI1000 0.35 RS_RS14095 glutamate 5-kinase 0.29 RS_RS14790 histidinol dehydrogenase — —
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS01810 glutamate 5-kinase 0.29 ABZR87_RS02500 histidinol dehydrogenase — —
Castellaniella sp019104865 MT123 0.35 ABCV34_RS10800 glutamate 5-kinase 0.31 ABCV34_RS11230 histidinol dehydrogenase low > 48
Pseudomonas stutzeri RCH2 0.35 Psest_3384 glutamate 5-kinase 0.32 Psest_3298 histidinol dehydrogenase 0.84 5
Dinoroseobacter shibae DFL-12 0.35 Dshi_1467 glutamate 5-kinase (RefSeq) 0.33 Dshi_0979 Histidinol dehydrogenase (RefSeq) — —
Rhizobium sp. OAE497 0.34 ABIE40_RS18920 glutamate 5-kinase 0.35 ABIE40_RS02725 histidinol dehydrogenase 0.92 2
Magnetospirillum magneticum AMB-1 0.34 AMB_RS20630 glutamate 5-kinase 0.33 AMB_RS16905 histidinol dehydrogenase — —
Acidovorax sp. GW101-3H11 0.34 Ac3H11_4771 Glutamate 5-kinase (EC 2.7.2.11) 0.31 Ac3H11_4724 Histidinol dehydrogenase (EC 1.1.1.23) — —
Sinorhizobium meliloti 1021 0.34 SMc03776 gamma-glutamyl kinase 0.35 SMc02307 histidinol dehydrogenase 0.80 58
Rhodopseudomonas palustris CGA009 0.34 TX73_000850 glutamate 5-kinase 0.33 TX73_023540 histidinol dehydrogenase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.34 GFF1274 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.30 GFF1314 Histidinol dehydrogenase (EC 1.1.1.23) — —
Agrobacterium fabrum C58 0.34 Atu2780 gamma-glutamyl kinase 0.34 Atu0537 histidinol dehydrogenase — —
Acinetobacter radioresistens SK82 0.34 MPMX26_02135 Glutamate 5-kinase 0.32 MPMX26_02587 Histidinol dehydrogenase low > 36
Caulobacter crescentus NA1000 Δfur 0.33 CCNA_00316 glutamate 5-kinase 0.29 CCNA_02431 histidinol dehydrogenase low > 67
Caulobacter crescentus NA1000 0.33 CCNA_00316 glutamate 5-kinase 0.29 CCNA_02431 histidinol dehydrogenase 0.93 10
Alteromonas macleodii MIT1002 0.33 MIT1002_04056 Glutamate 5-kinase 0.53 MIT1002_02633 Histidinol dehydrogenase low > 70
Desulfovibrio vulgaris Miyazaki F 0.33 DvMF_1377 gamma-glutamyl kinase (RefSeq) 0.29 DvMF_2814 hisD histidinol dehydrogenase (RefSeq) 0.95 14
Marinobacter adhaerens HP15 0.33 HP15_508 gamma-glutamyl kinase 0.33 HP15_2428 histidinol dehydrogenase — —
Variovorax sp. SCN45 0.33 GFF2515 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.32 GFF5345 Histidinol dehydrogenase (EC 1.1.1.23) — —
Rhodospirillum rubrum S1H 0.33 Rru_A1239 Glutamate 5-kinase, ProB-related (NCBI) 0.32 Rru_A2771 Histidinol dehydrogenase (NCBI) 0.75 7
Desulfovibrio vulgaris Hildenborough JW710 0.32 DVU0930 proB glutamate 5-kinase (TIGR) 0.29 DVU0796 hisD histidinol dehydrogenase (TIGR) 0.84 23
Bifidobacterium breve UCC2003 0.31 BBR_RS19445 glutamate 5-kinase 0.26 BBR_RS17055 histidinol dehydrogenase low > 34
Bosea sp. OAE506 0.31 ABIE41_RS07585 glutamate 5-kinase 0.32 ABIE41_RS24015 histidinol dehydrogenase — —
Phaeobacter inhibens DSM 17395 0.31 PGA1_c15510 glutamate 5-kinase ProB 0.34 PGA1_c31190 histidinol dehydrogenase HisD — —
Rhodanobacter denitrificans FW104-10B01 0.30 LRK54_RS02375 glutamate 5-kinase 0.51 LRK54_RS01605 histidinol dehydrogenase 0.69 32
Rhodanobacter denitrificans MT42 0.30 LRK55_RS02130 glutamate 5-kinase 0.51 LRK55_RS01385 histidinol dehydrogenase low > 63
Xanthomonas campestris pv. campestris strain 8004 0.30 Xcc-8004.2326.1 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.49 Xcc-8004.2948.1 Histidinol dehydrogenase (EC 1.1.1.23) 0.53 68
Rhodanobacter sp. FW510-T8 0.30 OKGIIK_09420 proB glutamate 5-kinase 0.51 OKGIIK_04950 hisD histidinol dehydrogenase low > 52
Brevundimonas sp. GW460-12-10-14-LB2 0.30 A4249_RS16125 glutamate 5-kinase 0.36 A4249_RS10695 histidinol dehydrogenase 0.98 30
Mycobacterium tuberculosis H37Rv 0.29 Rv2439c Probable glutamate 5-kinase protein ProB (gamma-glutamyl kinase) (GK) 0.26 Rv1599 Probable histidinol dehydrogenase HisD (HDH) — —
Lysobacter sp. OAE881 0.28 ABIE51_RS13370 glutamate 5-kinase 0.49 ABIE51_RS13325 histidinol dehydrogenase 0.82 26
Echinicola vietnamensis KMM 6221, DSM 17526 0.28 Echvi_4033 glutamate 5-kinase (EC 2.7.2.11) (from data) 0.47 Echvi_2459 histidinol dehydrogenase 0.71 37
Dyella japonica UNC79MFTsu3.2 0.28 ABZR86_RS08685 glutamate 5-kinase 0.51 ABZR86_RS06730 histidinol dehydrogenase 0.88 19
Mucilaginibacter yixingensis YX-36 DSM 26809 0.27 ABZR88_RS22170 glutamate 5-kinase 0.46 ABZR88_RS06880 histidinol dehydrogenase — —
Pedobacter sp. GW460-11-11-14-LB5 0.27 CA265_RS20855 glutamate 5-kinase (EC 2.7.2.11) (from data) 0.45 CA265_RS03635 histidinol dehydrogenase 0.90 33
Parabacteroides merdae CL09T00C40 0.27 HMPREF1078_RS10650 glutamate 5-kinase 0.46 HMPREF1078_RS02450 histidinol dehydrogenase 0.98 12
Bacteroides ovatus ATCC 8483 0.26 BACOVA_03537 glutamate 5-kinase 0.49 BACOVA_01234 histidinol dehydrogenase 0.93 32
Pontibacter actiniarum KMM 6156, DSM 19842 0.26 CA264_07725 glutamate 5-kinase 0.45 CA264_05030 histidinol dehydrogenase low > 74
Bacteroides stercoris CC31F 0.25 HMPREF1181_RS03325 glutamate 5-kinase 0.49 HMPREF1181_RS04860 histidinol dehydrogenase 0.97 3
Bacteroides thetaiotaomicron VPI-5482 0.25 BT3719 glutamate 5-kinase (EC 2.7.2.11) (from data) 0.48 BT0201 histidinol dehydrogenase (NCBI ptt file) 0.91 8
Phocaeicola vulgatus CL09T03C04 0.25 HMPREF1058_RS08650 glutamate 5-kinase 0.49 HMPREF1058_RS15875 histidinol dehydrogenase 0.97 4
Phocaeicola dorei CL03T12C01 0.25 ABI39_RS02880 glutamate 5-kinase 0.49 ABI39_RS11835 histidinol dehydrogenase 0.83 27
Sphingomonas koreensis DSMZ 15582 0.21 Ga0059261_3512 glutamate 5-kinase (EC 2.7.2.11) (from data) 0.32 Ga0059261_1281 histidinol dehydrogenase 0.89 31

Not shown: 1 genomes with orthologs for HER17_RS04700 only; 3 genomes with orthologs for HER17_RS12230 only