Conservation of cofitness between GFF1274 and GFF2806 in Hydrogenophaga sp. GW460-11-11-14-LB1

97 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Hydrogenophaga sp. GW460-11-11-14-LB1 1.0 GFF1274 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 1.0 GFF2806 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.85 6
Variovorax sp. OAS795 0.78 ABID97_RS23400 glutamate 5-kinase 0.61 ABID97_RS01555 pyrroline-5-carboxylate reductase — —
Acidovorax sp. GW101-3H11 0.77 Ac3H11_4771 Glutamate 5-kinase (EC 2.7.2.11) 0.62 Ac3H11_788 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) — —
Variovorax sp. SCN45 0.76 GFF2515 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.59 GFF5553 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) — —
Paraburkholderia sabiae LMG 24235 0.64 QEN71_RS27270 glutamate 5-kinase 0.45 QEN71_RS26600 pyrroline-5-carboxylate reductase 0.97 6
Paraburkholderia graminis OAS925 0.64 ABIE53_003588 glutamate 5-kinase 0.46 ABIE53_000840 pyrroline-5-carboxylate reductase 0.86 1
Paraburkholderia bryophila 376MFSha3.1 0.63 H281DRAFT_06264 glutamate 5-kinase 0.45 H281DRAFT_04679 pyrroline-5-carboxylate reductase 0.78 1
Burkholderia phytofirmans PsJN 0.63 BPHYT_RS17110 glutamate 5-kinase 0.45 BPHYT_RS03490 pyrroline-5-carboxylate reductase — —
Ralstonia solanacearum IBSBF1503 0.63 RALBFv3_RS06145 glutamate 5-kinase 0.47 RALBFv3_RS05580 pyrroline-5-carboxylate reductase low > 76
Ralstonia solanacearum UW163 0.63 UW163_RS07480 glutamate 5-kinase 0.47 UW163_RS08045 pyrroline-5-carboxylate reductase — —
Cupriavidus basilensis FW507-4G11 0.62 RR42_RS17940 gamma-glutamyl kinase 0.48 RR42_RS17360 pyrroline-5-carboxylate reductase — —
Ralstonia sp. UNC404CL21Col 0.62 ABZR87_RS01810 glutamate 5-kinase 0.49 ABZR87_RS01230 pyrroline-5-carboxylate reductase — —
Ralstonia solanacearum PSI07 0.61 RPSI07_RS11095 glutamate 5-kinase 0.46 RPSI07_RS11720 pyrroline-5-carboxylate reductase 0.64 22
Ralstonia solanacearum GMI1000 0.61 RS_RS14095 glutamate 5-kinase 0.50 RS_RS13440 pyrroline-5-carboxylate reductase — —
Castellaniella sp019104865 MT123 0.60 ABCV34_RS10800 glutamate 5-kinase 0.41 ABCV34_RS03610 pyrroline-5-carboxylate reductase 0.45 14
Dechlorosoma suillum PS 0.60 Dsui_0166 glutamate 5-kinase 0.43 Dsui_0602 pyrroline-5-carboxylate reductase — —
Herbaspirillum seropedicae SmR1 0.60 HSERO_RS01815 gamma-glutamyl kinase 0.41 HSERO_RS18990 pyrroline-5-carboxylate reductase 0.88 3
Pseudomonas fluorescens SBW25-INTG 0.52 PFLU_RS25360 glutamate 5-kinase 0.38 PFLU_RS28375 pyrroline-5-carboxylate reductase — —
Pseudomonas fluorescens SBW25 0.52 PFLU_RS25360 glutamate 5-kinase 0.38 PFLU_RS28375 pyrroline-5-carboxylate reductase — —
Pseudomonas stutzeri RCH2 0.52 Psest_3384 glutamate 5-kinase 0.37 Psest_0283 pyrroline-5-carboxylate reductase — —
Pseudomonas simiae WCS417 0.51 PS417_23545 gamma-glutamyl kinase 0.37 PS417_26730 pyrroline-5-carboxylate reductase 0.70 3
Pseudomonas fluorescens FW300-N1B4 0.51 Pf1N1B4_2800 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.38 Pf1N1B4_2341 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.50 Psyr_0704 glutamate 5-kinase 0.36 Psyr_0476 pyrroline-5-carboxylate reductase 0.87 17
Pseudomonas syringae pv. syringae B728a 0.50 Psyr_0704 glutamate 5-kinase 0.36 Psyr_0476 pyrroline-5-carboxylate reductase — —
Pseudomonas sp. S08-1 0.50 OH686_16305 Glutamate 5-kinase / RNA-binding C-terminal domain PUA 0.39 OH686_10980 pyrroline-5-carboxylate reductase 0.74 18
Pseudomonas putida KT2440 0.49 PP_0691 Glutamate 5-kinase 0.38 PP_5095 pyrroline-5-carboxylate reductase 0.59 6
Pseudomonas fluorescens GW456-L13 0.49 PfGW456L13_1472 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.37 PfGW456L13_1010 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.97 1
Pseudomonas fluorescens FW300-N2C3 0.49 AO356_15815 gamma-glutamyl kinase 0.37 AO356_13420 pyrroline-5-carboxylate reductase — —
Pseudomonas fluorescens FW300-N2E2 0.49 Pf6N2E2_5103 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.38 Pf6N2E2_4600 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) — —
Pseudomonas sp. RS175 0.49 PFR28_03769 Glutamate 5-kinase 0.38 PFR28_04243 Pyrroline-5-carboxylate reductase — —
Pseudomonas fluorescens FW300-N2E3 0.49 AO353_14115 gamma-glutamyl kinase 0.36 AO353_08165 pyrroline-5-carboxylate reductase 0.77 9
Marinobacter adhaerens HP15 0.47 HP15_508 gamma-glutamyl kinase 0.34 HP15_287 pyrroline-5-carboxylate reductase — —
Acinetobacter radioresistens SK82 0.43 MPMX26_02135 Glutamate 5-kinase 0.36 MPMX26_00572 Pyrroline-5-carboxylate reductase 0.97 2
Azospirillum sp. SherDot2 0.38 MPMX19_01933 Glutamate 5-kinase 0.24 MPMX19_01399 Pyrroline-5-carboxylate reductase — —
Synechococcus elongatus PCC 7942 0.37 Synpcc7942_2197 proB gamma-glutamyl kinase 0.24 Synpcc7942_2058 proC pyrroline-5-carboxylate reductase — —
Azospirillum brasilense Sp245 0.37 AZOBR_RS04095 glutamate 5-kinase 0.26 AZOBR_RS06245 pyrroline-5-carboxylate reductase — —
Erwinia tracheiphila SCR3 0.36 LU632_RS01185 proB glutamate 5-kinase 0.23 LU632_RS18995 proC pyrroline-5-carboxylate reductase 0.63 65
Shewanella amazonensis SB2B 0.36 Sama_2516 gamma-glutamyl kinase (RefSeq) 0.34 Sama_2478 pyrroline-5-carboxylate reductase (RefSeq) 0.97 2
Bosea sp. OAE506 0.36 ABIE41_RS07585 glutamate 5-kinase 0.21 ABIE41_RS11365 pyrroline-5-carboxylate reductase — —
Rhizobium sp. OAE497 0.36 ABIE40_RS18920 glutamate 5-kinase 0.30 ABIE40_RS13005 pyrroline-5-carboxylate reductase low > 107
Agrobacterium fabrum C58 0.36 Atu2780 gamma-glutamyl kinase 0.29 Atu2209 pyrroline-5-carboxylate reductase — —
Shewanella loihica PV-4 0.36 Shew_2848 gamma-glutamyl kinase (RefSeq) 0.33 Shew_1136 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.96 31
Escherichia coli ECRC62 0.35 BNILDI_00245 proB Glutamate 5-kinase 0.25 BNILDI_22950 proC pyrroline-5-carboxylate reductase — —
Escherichia coli Nissle 1917 0.35 ECOLIN_RS01825 glutamate 5-kinase 0.25 ECOLIN_RS02345 pyrroline-5-carboxylate reductase low > 52
Escherichia coli ECRC102 0.35 NIAGMN_07535 proB Glutamate 5-kinase 0.25 NIAGMN_06665 proC pyrroline-5-carboxylate reductase — —
Escherichia coli ECOR38 0.35 HEPCGN_07780 proB Glutamate 5-kinase 0.25 HEPCGN_07250 proC pyrroline-5-carboxylate reductase low > 85
Escherichia coli BL21 0.35 ECD_00239 gamma-glutamate kinase 0.25 ECD_00333 pyrroline-5-carboxylate reductase, NAD(P)-binding low > 60
Escherichia coli ECRC99 0.35 KEDOAH_18480 proB Glutamate 5-kinase 0.25 KEDOAH_19355 proC pyrroline-5-carboxylate reductase — —
Escherichia fergusonii Becca 0.35 EFB2_03778 Glutamate 5-kinase 0.25 EFB2_03670 Pyrroline-5-carboxylate reductase low > 86
Escherichia coli ECRC98 0.35 JDDGAC_13300 proB Glutamate 5-kinase 0.25 JDDGAC_12265 proC pyrroline-5-carboxylate reductase — —
Escherichia coli ECOR27 0.35 NOLOHH_02050 proB Glutamate 5-kinase 0.25 NOLOHH_01535 proC pyrroline-5-carboxylate reductase low > 57
Escherichia coli BW25113 0.35 b0242 proB gamma-glutamyl kinase (NCBI) 0.25 b0386 proC pyrroline-5-carboxylate reductase (NCBI) 0.90 36
Serratia liquefaciens MT49 0.35 IAI46_04430 glutamate 5-kinase 0.31 IAI46_21415 pyrroline-5-carboxylate reductase low > 86
Escherichia coli ECRC101 0.35 OKFHMN_09675 proB Glutamate 5-kinase 0.25 OKFHMN_08610 proC pyrroline-5-carboxylate reductase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.35 OHPLBJKB_03398 Glutamate 5-kinase 0.25 OHPLBJKB_03288 Pyrroline-5-carboxylate reductase low > 73
Escherichia coli ECRC101 0.35 MCAODC_00195 proB Glutamate 5-kinase 0.25 MCAODC_27835 proC pyrroline-5-carboxylate reductase — —
Rhodospirillum rubrum S1H 0.35 Rru_A1239 Glutamate 5-kinase, ProB-related (NCBI) 0.26 Rru_A3281 Delta 1-pyrroline-5-carboxylate reductase (NCBI) — —
Phaeobacter inhibens DSM 17395 0.35 PGA1_c15510 glutamate 5-kinase ProB 0.24 PGA1_c24700 pyrroline-5-carboxylate reductase ProC 0.96 2
Magnetospirillum magneticum AMB-1 0.35 AMB_RS20630 glutamate 5-kinase 0.25 AMB_RS02820 pyrroline-5-carboxylate reductase — —
Enterobacter asburiae PDN3 0.35 EX28DRAFT_2651 glutamate 5-kinase 0.24 EX28DRAFT_2585 pyrroline-5-carboxylate reductase 0.76 40
Pantoea sp. MT58 0.35 IAI47_15120 glutamate 5-kinase 0.25 IAI47_14945 pyrroline-5-carboxylate reductase 0.89 32
Enterobacter sp. TBS_079 0.35 MPMX20_00927 Glutamate 5-kinase 0.24 MPMX20_00976 Pyrroline-5-carboxylate reductase 0.93 7
Sinorhizobium meliloti 1021 0.35 SMc03776 gamma-glutamyl kinase 0.28 SMc02677 pyrroline-5-carboxylate reductase 0.66 84
Vibrio cholerae E7946 ATCC 55056 0.35 CSW01_11575 glutamate 5-kinase 0.28 CSW01_02450 pyrroline-5-carboxylate reductase low > 62
Klebsiella michiganensis M5al 0.35 BWI76_RS05840 glutamate 5-kinase 0.25 BWI76_RS06170 pyrroline-5-carboxylate reductase — —
Rahnella sp. WP5 0.35 EX31_RS20980 glutamate 5-kinase 0.31 EX31_RS02690 pyrroline-5-carboxylate reductase 0.96 24
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.35 GFF4114 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.24 GFF4283 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) low > 78
Rhodopseudomonas palustris CGA009 0.34 TX73_000850 glutamate 5-kinase 0.27 TX73_022630 pyrroline-5-carboxylate reductase — —
Rhodanobacter denitrificans FW104-10B01 0.34 LRK54_RS02375 glutamate 5-kinase 0.26 LRK54_RS04260 pyrroline-5-carboxylate reductase 0.72 25
Rhodanobacter denitrificans MT42 0.34 LRK55_RS02130 glutamate 5-kinase 0.26 LRK55_RS04030 pyrroline-5-carboxylate reductase — —
Desulfovibrio vulgaris Miyazaki F 0.33 DvMF_1377 gamma-glutamyl kinase (RefSeq) 0.21 DvMF_3161 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.96 7
Caulobacter crescentus NA1000 Δfur 0.33 CCNA_00316 glutamate 5-kinase 0.21 CCNA_00528 pyrroline-5-carboxylate reductase low > 67
Shewanella oneidensis MR-1 0.33 SO1121 proB glutamate 5-kinase (NCBI ptt file) 0.32 SO3354 proC pyrroline-5-carboxylate reductase (NCBI ptt file) 0.99 2
Caulobacter crescentus NA1000 0.33 CCNA_00316 glutamate 5-kinase 0.21 CCNA_00528 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.99 1
Shewanella sp. ANA-3 0.33 Shewana3_0954 gamma-glutamyl kinase (RefSeq) 0.33 Shewana3_1193 pyrroline-5-carboxylate reductase (RefSeq) 0.97 2
Dinoroseobacter shibae DFL-12 0.33 Dshi_1467 glutamate 5-kinase (RefSeq) 0.22 Dshi_2645 pyrroline-5-carboxylate reductase (RefSeq) — —
Rhodanobacter sp. FW510-T8 0.32 OKGIIK_09420 proB glutamate 5-kinase 0.28 OKGIIK_11135 proC pyrroline-5-carboxylate reductase low > 52
Desulfovibrio vulgaris Hildenborough JW710 0.32 DVU0930 proB glutamate 5-kinase (TIGR) 0.23 DVU2332 proC pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.91 2
Pectobacterium carotovorum WPP14 0.32 HER17_RS04700 glutamate 5-kinase 0.30 HER17_RS03805 pyrroline-5-carboxylate reductase — —
Dickeya dadantii 3937 0.31 DDA3937_RS16535 glutamate 5-kinase 0.32 DDA3937_RS17305 pyrroline-5-carboxylate reductase 0.87 3
Dickeya dianthicola ME23 0.31 DZA65_RS17695 glutamate 5-kinase 0.32 DZA65_RS18440 pyrroline-5-carboxylate reductase — —
Dickeya dianthicola 67-19 0.31 HGI48_RS16605 glutamate 5-kinase 0.31 HGI48_RS17350 pyrroline-5-carboxylate reductase — —
Bifidobacterium breve UCC2003 0.30 BBR_RS19445 glutamate 5-kinase 0.11 BBR_RS14625 pyrroline-5-carboxylate reductase 0.83 1
Dyella japonica UNC79MFTsu3.2 0.29 ABZR86_RS08685 glutamate 5-kinase 0.33 ABZR86_RS10425 pyrroline-5-carboxylate reductase 0.90 5
Lysobacter sp. OAE881 0.29 ABIE51_RS13370 glutamate 5-kinase 0.37 ABIE51_RS16065 pyrroline-5-carboxylate reductase 0.78 56
Xanthomonas campestris pv. campestris strain 8004 0.27 Xcc-8004.2326.1 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.34 Xcc-8004.1710.1 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.55 54
Brevundimonas sp. GW460-12-10-14-LB2 0.27 A4249_RS16125 glutamate 5-kinase 0.19 A4249_RS09840 pyrroline-5-carboxylate reductase dimerization domain-containing protein 0.98 42
Alteromonas macleodii MIT1002 0.27 MIT1002_04056 Glutamate 5-kinase 0.26 MIT1002_03062 Pyrroline-5-carboxylate reductase low > 70
Mycobacterium tuberculosis H37Rv 0.26 Rv2439c Probable glutamate 5-kinase protein ProB (gamma-glutamyl kinase) (GK) 0.19 Rv0500 Probable pyrroline-5-carboxylate reductase ProC (P5CR) (P5C reductase) — —
Pedobacter sp. GW460-11-11-14-LB5 0.26 CA265_RS20855 glutamate 5-kinase (EC 2.7.2.11) (from data) 0.13 CA265_RS18505 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.96 2
Pontibacter actiniarum KMM 6156, DSM 19842 0.24 CA264_07725 glutamate 5-kinase 0.16 CA264_07730 pyrroline-5-carboxylate reductase 0.83 1
Echinicola vietnamensis KMM 6221, DSM 17526 0.24 Echvi_4033 glutamate 5-kinase (EC 2.7.2.11) (from data) 0.27 Echvi_2635 pyrroline-5-carboxylate reductase 0.77 10
Bacteroides thetaiotaomicron VPI-5482 0.24 BT3719 glutamate 5-kinase (EC 2.7.2.11) (from data) 0.16 BT1902 pyrroline-5-carboxylate reductase (NCBI ptt file) low > 81
Parabacteroides merdae CL09T00C40 0.24 HMPREF1078_RS10650 glutamate 5-kinase 0.16 HMPREF1078_RS10620 pyrroline-5-carboxylate reductase 0.97 18
Bacteroides stercoris CC31F 0.23 HMPREF1181_RS03325 glutamate 5-kinase 0.15 HMPREF1181_RS03440 pyrroline-5-carboxylate reductase 0.96 6
Phocaeicola dorei CL03T12C01 0.23 ABI39_RS02880 glutamate 5-kinase 0.18 ABI39_RS02960 pyrroline-5-carboxylate reductase 0.85 21
Phocaeicola vulgatus CL09T03C04 0.23 HMPREF1058_RS08650 glutamate 5-kinase 0.18 HMPREF1058_RS08830 pyrroline-5-carboxylate reductase 0.96 8
Bacteroides ovatus ATCC 8483 0.22 BACOVA_03537 glutamate 5-kinase 0.18 BACOVA_03587 pyrroline-5-carboxylate reductase 0.93 30

Not shown: 2 genomes with orthologs for GFF1274 only; 1 genomes with orthologs for GFF2806 only