| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Phaeobacter inhibens DSM 17395 | 1.0 | PGA1_c29780 | | 3-isopropylmalate dehydratase large subunit | 1.0 | PGA1_c11870 | | serine hydroxymethyltransferase GlyA | 0.95 | 3 |
| Dinoroseobacter shibae DFL-12 | 0.85 | Dshi_0085 | | 3-isopropylmalate dehydratase, large subunit (RefSeq) | 0.82 | Dshi_0821 | | Glycine hydroxymethyltransferase (RefSeq) | 0.69 | 20 |
| Azospirillum sp. SherDot2 | 0.75 | MPMX19_01998 | | 3-isopropylmalate dehydratase large subunit | 0.69 | MPMX19_00727 | | Serine hydroxymethyltransferase 2 | — | — |
| Azospirillum brasilense Sp245 | 0.73 | AZOBR_RS03545 | | isopropylmalate isomerase | 0.69 | AZOBR_RS10015 | | serine hydroxymethyltransferase | — | — |
| Sinorhizobium meliloti 1021 | 0.73 | SMc03823 | | isopropylmalate isomerase large subunit | 0.72 | SMc01770 | | serine hydroxymethyltransferase | 0.92 | 32 |
| Bosea sp. OAE506 | 0.72 | ABIE41_RS11660 | | 3-isopropylmalate dehydratase large subunit | 0.72 | ABIE41_RS19780 | | serine hydroxymethyltransferase | — | — |
| Agrobacterium fabrum C58 | 0.72 | Atu2709 | | 3-isopropylmalate dehydratase, large subunit | 0.73 | Atu1165 | | serine hydroxymethyltransferase | — | — |
| Magnetospirillum magneticum AMB-1 | 0.71 | AMB_RS20560 | | 3-isopropylmalate dehydratase large subunit | 0.68 | AMB_RS11815 | | serine hydroxymethyltransferase | — | — |
| Rhizobium sp. OAE497 | 0.71 | ABIE40_RS18380 | | 3-isopropylmalate dehydratase large subunit | 0.71 | ABIE40_RS06715 | | serine hydroxymethyltransferase | — | — |
| Rhodospirillum rubrum S1H | 0.70 | Rru_A1189 | | 3-isopropylmalate dehydratase large subunit region (NCBI) | 0.72 | Rru_A1827 | | Glycine hydroxymethyltransferase (NCBI) | 0.73 | 41 |
| Rhodopseudomonas palustris CGA009 | 0.69 | TX73_001245 | | 3-isopropylmalate dehydratase large subunit | 0.67 | TX73_014115 | | serine hydroxymethyltransferase | — | — |
| Caulobacter crescentus NA1000 | 0.65 | CCNA_00196 | | 3-isopropylmalate dehydratase large subunit | 0.68 | CCNA_01419 | | serine hydroxymethyltransferase | — | — |
| Caulobacter crescentus NA1000 Δfur | 0.65 | CCNA_00196 | | 3-isopropylmalate dehydratase large subunit | 0.68 | CCNA_01419 | | serine hydroxymethyltransferase | low | > 67 |
| Escherichia fergusonii Becca | 0.64 | EFB2_03973 | | 3-isopropylmalate dehydratase large subunit | 0.52 | EFB2_01345 | | Serine hydroxymethyltransferase | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.64 | Ga0059261_4223 | | 3-isopropylmalate dehydratase, large subunit | 0.63 | Ga0059261_1986 | | Glycine/serine hydroxymethyltransferase | 0.96 | 36 |
| Kangiella aquimarina DSM 16071 | 0.64 | B158DRAFT_1319 | | 3-isopropylmalate dehydratase, large subunit | 0.57 | B158DRAFT_1908 | | Glycine/serine hydroxymethyltransferase | low | > 40 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.64 | OHPLBJKB_03585 | | 3-isopropylmalate dehydratase large subunit | 0.52 | OHPLBJKB_01156 | | Serine hydroxymethyltransferase | low | > 73 |
| Escherichia coli ECOR38 | 0.64 | HEPCGN_08705 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.52 | HEPCGN_20655 | glyA | serine hydroxymethyltransferase | low | > 85 |
| Escherichia coli BW25113 | 0.64 | b0072 | leuC | isopropylmalate isomerase large subunit (NCBI) | 0.52 | b2551 | glyA | serine hydroxymethyltransferase (NCBI) | — | — |
| Escherichia coli ECRC62 | 0.64 | BNILDI_08540 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.52 | BNILDI_11985 | glyA | serine hydroxymethyltransferase | — | — |
| Escherichia coli Nissle 1917 | 0.64 | ECOLIN_RS00390 | | 3-isopropylmalate dehydratase large subunit | 0.52 | ECOLIN_RS14440 | | serine hydroxymethyltransferase | — | — |
| Escherichia coli ECOR27 | 0.64 | NOLOHH_03070 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.52 | NOLOHH_13185 | glyA | serine hydroxymethyltransferase | low | > 57 |
| Escherichia coli BL21 | 0.64 | ECD_00074 | | 3-isopropylmalate dehydratase large subunit | 0.52 | ECD_02443 | | serine hydroxymethyltransferase | low | > 60 |
| Escherichia coli ECRC99 | 0.64 | KEDOAH_17430 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.52 | KEDOAH_06710 | glyA | serine hydroxymethyltransferase | — | — |
| Escherichia coli ECRC101 | 0.64 | OKFHMN_10725 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.52 | OKFHMN_21510 | glyA | serine hydroxymethyltransferase | — | — |
| Escherichia coli ECRC101 | 0.64 | MCAODC_01240 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.52 | MCAODC_12040 | glyA | serine hydroxymethyltransferase | — | — |
| Escherichia coli ECRC98 | 0.64 | JDDGAC_14320 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.52 | JDDGAC_25175 | glyA | serine hydroxymethyltransferase | — | — |
| Escherichia coli ECRC102 | 0.64 | NIAGMN_08575 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | 0.52 | NIAGMN_19280 | glyA | serine hydroxymethyltransferase | — | — |
| Marinobacter adhaerens HP15 | 0.64 | HP15_1834 | | protein containing 3-isopropylmalate dehydratase, large subunit region domain | 0.60 | HP15_489 | | glycine hydroxymethyltransferase | — | — |
| Pseudomonas sp. S08-1 | 0.64 | OH686_04480 | | 3-isopropylmalate dehydratase large subunit | 0.58 | OH686_16230 | | Serine hydroxymethyltransferase | — | — |
| Klebsiella michiganensis M5al | 0.64 | BWI76_RS04670 | | 3-isopropylmalate dehydratase large subunit | 0.52 | BWI76_RS21225 | | serine hydroxymethyltransferase | — | — |
| Dickeya dianthicola ME23 | 0.64 | DZA65_RS19210 | | 3-isopropylmalate dehydratase large subunit | 0.56 | DZA65_RS16775 | | serine hydroxymethyltransferase | — | — |
| Dickeya dianthicola 67-19 | 0.64 | HGI48_RS18065 | | 3-isopropylmalate dehydratase large subunit | 0.56 | HGI48_RS15700 | | serine hydroxymethyltransferase | — | — |
| Dickeya dadantii 3937 | 0.64 | DDA3937_RS18125 | | 3-isopropylmalate dehydratase large subunit | 0.56 | DDA3937_RS15600 | | serine hydroxymethyltransferase | — | — |
| Rahnella sp. WP5 | 0.64 | EX31_RS03690 | | 3-isopropylmalate dehydratase large subunit | 0.55 | EX31_RS20585 | | serine hydroxymethyltransferase | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.64 | RR42_RS14400 | | isopropylmalate isomerase | 0.58 | RR42_RS15485 | | serine hydroxymethyltransferase | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.64 | AO356_21400 | | isopropylmalate isomerase | 0.57 | AO356_15725 | | serine hydroxymethyltransferase | — | — |
| Enterobacter asburiae PDN3 | 0.64 | EX28DRAFT_3668 | | 3-isopropylmalate dehydratase, large subunit | 0.52 | EX28DRAFT_0099 | | Glycine/serine hydroxymethyltransferase | — | — |
| Ralstonia sp. UNC404CL21Col | 0.64 | ABZR87_RS14540 | | 3-isopropylmalate dehydratase large subunit | 0.59 | ABZR87_RS08955 | | serine hydroxymethyltransferase | — | — |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.64 | GFF166 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.53 | GFF2447 | | Serine hydroxymethyltransferase (EC 2.1.2.1) | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.64 | Pf6N2E2_63 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.58 | Pf6N2E2_5082 | | Serine hydroxymethyltransferase (EC 2.1.2.1) | — | — |
| Pseudomonas sp. RS175 | 0.63 | PFR28_02824 | | 3-isopropylmalate dehydratase large subunit | 0.58 | PFR28_03786 | | Serine hydroxymethyltransferase | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.63 | PfGW456L13_3948 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.57 | PfGW456L13_1451 | | Serine hydroxymethyltransferase (EC 2.1.2.1) | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.63 | Pf1N1B4_15 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.58 | Pf1N1B4_2778 | | Serine hydroxymethyltransferase (EC 2.1.2.1) | — | — |
| Enterobacter sp. TBS_079 | 0.63 | MPMX20_00767 | | 3-isopropylmalate dehydratase large subunit 1 | 0.52 | MPMX20_03420 | | Serine hydroxymethyltransferase | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.63 | AO353_20620 | | isopropylmalate isomerase | 0.58 | AO353_14020 | | serine hydroxymethyltransferase | — | — |
| Ralstonia solanacearum PSI07 | 0.63 | RPSI07_RS14695 | | 3-isopropylmalate dehydratase large subunit | 0.57 | RPSI07_RS20330 | | serine hydroxymethyltransferase | 0.63 | 31 |
| Pectobacterium carotovorum WPP14 | 0.63 | HER17_RS03075 | | 3-isopropylmalate dehydratase large subunit | 0.56 | HER17_RS01990 | | serine hydroxymethyltransferase | low | > 75 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.63 | Xcc-8004.1049.1 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.58 | Xcc-8004.4398.1 | | Serine hydroxymethyltransferase (EC 2.1.2.1) | 0.76 | 42 |
| Pantoea sp. MT58 | 0.63 | IAI47_16010 | | 3-isopropylmalate dehydratase large subunit | 0.56 | IAI47_04960 | | serine hydroxymethyltransferase | — | — |
| Paraburkholderia graminis OAS925 | 0.63 | ABIE53_004801 | | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit | 0.65 | ABIE53_006138 | | glycine hydroxymethyltransferase | low | > 113 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.63 | H281DRAFT_06075 | | 3-isopropylmalate dehydratase, large subunit | 0.66 | H281DRAFT_02468 | | serine hydroxymethyltransferase | low | > 103 |
| Pseudomonas syringae pv. syringae B728a | 0.63 | Psyr_1983 | | 3-isopropylmalate dehydratase, large subunit | 0.57 | Psyr_4270 | | serine hydroxymethyltransferase | 0.90 | 12 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.63 | Psyr_1983 | | 3-isopropylmalate dehydratase, large subunit | 0.57 | Psyr_4270 | | serine hydroxymethyltransferase | 0.94 | 6 |
| Serratia liquefaciens MT49 | 0.62 | IAI46_03345 | | 3-isopropylmalate dehydratase large subunit | 0.55 | IAI46_19395 | | serine hydroxymethyltransferase | — | — |
| Castellaniella sp019104865 MT123 | 0.62 | ABCV34_RS04290 | | 3-isopropylmalate dehydratase large subunit | 0.55 | ABCV34_RS06400 | | serine hydroxymethyltransferase | low | > 48 |
| Pseudomonas simiae WCS417 | 0.62 | PS417_18600 | | isopropylmalate isomerase | 0.58 | PS417_24280 | | serine hydroxymethyltransferase | — | — |
| Pseudomonas stutzeri RCH2 | 0.62 | Psest_2591 | | 3-isopropylmalate dehydratase, large subunit | 0.59 | Psest_3404 | | Glycine/serine hydroxymethyltransferase | — | — |
| Pseudomonas putida KT2440 | 0.62 | PP_1985 | | 3-isopropylmalate dehydratase large subunit | 0.58 | PP_0671 | | serine hydroxymethyltransferase | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.62 | RALBFv3_RS02620 | | 3-isopropylmalate dehydratase large subunit | 0.58 | RALBFv3_RS12895 | | serine hydroxymethyltransferase | — | — |
| Herbaspirillum seropedicae SmR1 | 0.62 | HSERO_RS16515 | | isopropylmalate isomerase | 0.59 | HSERO_RS06140 | | serine hydroxymethyltransferase | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.62 | QEN71_RS17605 | | 3-isopropylmalate dehydratase large subunit | 0.66 | QEN71_RS08310 | | serine hydroxymethyltransferase | low | > 153 |
| Ralstonia solanacearum UW163 | 0.62 | UW163_RS11105 | | 3-isopropylmalate dehydratase large subunit | 0.58 | UW163_RS00670 | | serine hydroxymethyltransferase | — | — |
| Pseudomonas fluorescens SBW25 | 0.62 | PFLU_RS20580 | | 3-isopropylmalate dehydratase large subunit | 0.57 | PFLU_RS26195 | | serine hydroxymethyltransferase | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.62 | PFLU_RS20580 | | 3-isopropylmalate dehydratase large subunit | 0.57 | PFLU_RS26195 | | serine hydroxymethyltransferase | — | — |
| Burkholderia phytofirmans PsJN | 0.62 | BPHYT_RS33915 | | isopropylmalate isomerase | 0.66 | BPHYT_RS25180 | | serine hydroxymethyltransferase | low | > 109 |
| Ralstonia solanacearum GMI1000 | 0.62 | RS_RS10000 | | 3-isopropylmalate dehydratase large subunit | 0.66 | RS_RS17460 | | serine hydroxymethyltransferase | low | > 80 |
| Acinetobacter radioresistens SK82 | 0.62 | MPMX26_00345 | | 3-isopropylmalate dehydratase large subunit | 0.55 | MPMX26_02049 | | Serine hydroxymethyltransferase | — | — |
| Variovorax sp. OAS795 | 0.62 | ABID97_RS08465 | | 3-isopropylmalate dehydratase large subunit | 0.55 | ABID97_RS17890 | | serine hydroxymethyltransferase | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.61 | GFF3363 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.57 | GFF5152 | | Serine hydroxymethyltransferase (EC 2.1.2.1) | — | — |
| Variovorax sp. SCN45 | 0.61 | GFF3890 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.55 | GFF560 | | Serine hydroxymethyltransferase (EC 2.1.2.1) | — | — |
| Mycobacterium tuberculosis H37Rv | 0.61 | Rv2988c | | Probable 3-isopropylmalate dehydratase (large subunit) LeuC (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI) | 0.52 | Rv0070c | | Serine hydroxymethyltransferase GlyA2 (serine methylase 2) (SHMT 2) | — | — |
| Dechlorosoma suillum PS | 0.60 | Dsui_3201 | | 3-isopropylmalate dehydratase, large subunit | 0.59 | Dsui_2254 | | glycine/serine hydroxymethyltransferase | — | — |
| Vibrio cholerae E7946 ATCC 55056 | 0.60 | CSW01_12605 | | 3-isopropylmalate dehydratase large subunit | 0.64 | CSW01_15340 | | serine hydroxymethyltransferase | low | > 62 |
| Erwinia tracheiphila SCR3 | 0.59 | LU632_RS02870 | leuC | 3-isopropylmalate dehydratase large subunit | 0.55 | LU632_RS17915 | | serine hydroxymethyltransferase | — | — |
| Alteromonas macleodii MIT1002 | 0.59 | MIT1002_00947 | | 3-isopropylmalate dehydratase large subunit | 0.54 | MIT1002_02702 | | Serine hydroxymethyltransferase | 0.95 | 43 |
| Shewanella loihica PV-4 | 0.59 | Shew_3470 | | isopropylmalate isomerase large subunit (RefSeq) | 0.58 | Shew_1185 | glyA | serine hydroxymethyltransferase (RefSeq) | 0.93 | 39 |
| Acidovorax sp. GW101-3H11 | 0.59 | Ac3H11_1525 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.57 | Ac3H11_2921 | | Serine hydroxymethyltransferase (EC 2.1.2.1) | — | — |
| Shewanella sp. ANA-3 | 0.59 | Shewana3_3759 | | isopropylmalate isomerase large subunit (RefSeq) | 0.57 | Shewana3_1094 | glyA | serine hydroxymethyltransferase (RefSeq) | 0.94 | 20 |
| Shewanella oneidensis MR-1 | 0.59 | SO4234 | leuC | 3-isopropylmalate dehydratase, large subunit (NCBI ptt file) | 0.57 | SO3471 | glyA | serine hydroxymethyltransferase (NCBI ptt file) | 0.93 | 40 |
| Shewanella amazonensis SB2B | 0.58 | Sama_0337 | | isopropylmalate isomerase large subunit (RefSeq) | 0.58 | Sama_1014 | glyA | serine hydroxymethyltransferase (RefSeq) | 0.90 | 50 |
| Rhodanobacter denitrificans FW104-10B01 | 0.56 | LRK54_RS07375 | | 3-isopropylmalate dehydratase large subunit | 0.58 | LRK54_RS04625 | | serine hydroxymethyltransferase | low | > 59 |
| Rhodanobacter denitrificans MT42 | 0.56 | LRK55_RS07105 | | 3-isopropylmalate dehydratase large subunit | 0.58 | LRK55_RS04400 | | serine hydroxymethyltransferase | low | > 63 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.54 | Echvi_2059 | | 3-isopropylmalate dehydratase, large subunit | 0.47 | Echvi_1188 | | Glycine/serine hydroxymethyltransferase | 0.72 | 16 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.54 | ABZR88_RS11595 | | 3-isopropylmalate dehydratase large subunit | 0.48 | ABZR88_RS00640 | | serine hydroxymethyltransferase | — | — |
| Phocaeicola dorei CL03T12C01 | 0.53 | ABI39_RS10200 | | 3-isopropylmalate dehydratase large subunit | 0.48 | ABI39_RS17420 | | serine hydroxymethyltransferase | 0.80 | 31 |
| Phocaeicola vulgatus CL09T03C04 | 0.53 | HMPREF1058_RS14550 | | 3-isopropylmalate dehydratase large subunit | 0.48 | HMPREF1058_RS03800 | | serine hydroxymethyltransferase | 0.80 | 23 |
| Bacteroides stercoris CC31F | 0.53 | HMPREF1181_RS14145 | | 3-isopropylmalate dehydratase large subunit | 0.49 | HMPREF1181_RS15010 | | serine hydroxymethyltransferase | low | > 56 |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.53 | CA265_RS15830 | | 3-isopropylmalate dehydratase large subunit | 0.48 | CA265_RS19165 | | serine hydroxymethyltransferase | 0.91 | 36 |
| Bacteroides ovatus ATCC 8483 | 0.53 | BACOVA_04603 | | 3-isopropylmalate dehydratase, large subunit | 0.49 | BACOVA_02446 | | glycine hydroxymethyltransferase | 0.95 | 17 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.52 | BT1860 | | 3-isopropylmalate dehydratase large subunit (NCBI ptt file) | 0.48 | BT0738 | | serine hydroxymethyltransferase (NCBI ptt file) | 0.87 | 23 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.52 | CA264_09435 | | 3-isopropylmalate dehydratase large subunit | 0.46 | CA264_17045 | | serine hydroxymethyltransferase | low | > 74 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.52 | A4249_RS10005 | | 3-isopropylmalate dehydratase large subunit | 0.61 | A4249_RS06040 | | serine hydroxymethyltransferase | — | — |
| Parabacteroides merdae CL09T00C40 | 0.51 | HMPREF1078_RS16660 | | 3-isopropylmalate dehydratase large subunit | 0.48 | HMPREF1078_RS02145 | | serine hydroxymethyltransferase | low | > 61 |
| Lysobacter sp. OAE881 | 0.50 | ABIE51_RS17575 | | 3-isopropylmalate dehydratase large subunit | 0.59 | ABIE51_RS04620 | | serine hydroxymethyltransferase | low | > 62 |
| Dyella japonica UNC79MFTsu3.2 | 0.50 | ABZR86_RS15960 | | 3-isopropylmalate dehydratase large subunit | 0.59 | ABZR86_RS10715 | | serine hydroxymethyltransferase | 0.89 | 64 |
| Rhodanobacter sp. FW510-T8 | 0.49 | OKGIIK_13585 | leuC | 3-isopropylmalate dehydratase large subunit | 0.59 | OKGIIK_11440 | glyA | serine hydroxymethyltransferase | low | > 52 |
| Synechococcus elongatus PCC 7942 | 0.49 | Synpcc7942_1898 | leuC | isopropylmalate isomerase large subunit | 0.60 | Synpcc7942_0282 | glyA | serine hydroxymethyltransferase | — | — |
| Desulfovibrio vulgaris Miyazaki F | 0.23 | DvMF_1792 | | 3-isopropylmalate dehydratase large subunit (RefSeq) | 0.56 | DvMF_3097 | glyA | serine hydroxymethyltransferase (RefSeq) | — | — |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.23 | DVU2982 | leuC | 3-isopropylmalate dehydratase / (R)-citramalate isomerase, large subunit LeuC (EC 4.2.1.33; EC 4.2.1.35) (from data) | 0.57 | DVU1203 | glyA | serine hydroxymethyltransferase (TIGR) | — | — |
Not shown: 3 genomes with orthologs for PGA1_c29780 only; 0 genomes with orthologs for PGA1_c11870 only