Conservation of cofitness between CSW01_11965 and CSW01_13550 in Vibrio cholerae E7946 ATCC 55056

108 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_11965 threonine synthase 1.0 CSW01_13550 O-succinylhomoserine (thiol)-lyase 0.52 7
Rahnella sp. WP5 0.69 EX31_RS03935 threonine synthase 0.56 EX31_RS14215 cystathionine gamma-synthase 0.99 9
Klebsiella pneumoniae MKP103 0.68 KDGMDA_12520 threonine synthase 0.59 KDGMDA_09295 cystathionine gamma-synthase low > 95
Dickeya dianthicola 67-19 0.68 HGI48_RS18335 threonine synthase 0.58 HGI48_RS20425 cystathionine gamma-synthase 0.63 39
Klebsiella michiganensis M5al 0.68 BWI76_RS04255 threonine synthase 0.58 BWI76_RS00785 cystathionine gamma-synthase 0.92 13
Dickeya dianthicola ME23 0.68 DZA65_RS19475 threonine synthase 0.58 DZA65_RS21470 cystathionine gamma-synthase 0.64 31
Dickeya dadantii 3937 0.68 DDA3937_RS18405 threonine synthase 0.59 DDA3937_RS00950 cystathionine gamma-synthase 0.72 50
Erwinia amylovora T8 0.68 OLJFJH_01485 threonine synthase 0.54 OLJFJH_06095 cystathionine gamma-synthase 0.86 38
Pantoea sp. MT58 0.68 IAI47_16205 threonine synthase 0.55 IAI47_00880 cystathionine gamma-synthase 0.93 15
Enterobacter asburiae PDN3 0.68 EX28DRAFT_3616 threonine synthase 0.59 EX28DRAFT_4411 cystathionine gamma-synthase (EC 2.5.1.48) 0.60 7
Enterobacter sp. TBS_079 0.68 MPMX20_00712 Threonine synthase 0.59 MPMX20_04531 Cystathionine gamma-synthase 0.93 9
Pantoea agglomerans CFBP13505 P0401 0.68 PagCFBP13505_RS21900 threonine synthase 0.56 PagCFBP13505_RS18460 cystathionine gamma-synthase low > 74
Serratia liquefaciens MT49 0.68 IAI46_03040 threonine synthase 0.59 IAI46_24540 cystathionine gamma-synthase low > 86
Erwinia tracheiphila SCR3 0.67 LU632_RS02620 thrC threonine synthase 0.57 LU632_RS19640 metB cystathionine gamma-synthase — —
Erwinia tracheiphila HP pepo 2.2 0.67 IJEDHG_06290 thrC threonine synthase 0.57 IJEDHG_13020 metB cystathionine gamma-synthase — —
Pectobacterium carotovorum WPP14 0.67 HER17_RS02805 threonine synthase 0.60 HER17_RS00910 cystathionine gamma-synthase 0.93 23
Escherichia coli Nissle 1917 0.66 ECOLIN_RS00020 threonine synthase 0.59 ECOLIN_RS22725 cystathionine gamma-synthase low > 55
Escherichia coli ECOR38 0.66 HEPCGN_09105 thrC threonine synthase 0.59 HEPCGN_12345 metB cystathionine gamma-synthase 0.82 62
Escherichia coli ECRC99 0.66 KEDOAH_17055 thrC threonine synthase 0.59 KEDOAH_14485 metB cystathionine gamma-synthase — —
Escherichia fergusonii Becca 0.66 EFB2_04039 Threonine synthase 0.59 EFB2_04679 Cystathionine gamma-synthase low > 86
Escherichia coli ECOR27 0.66 NOLOHH_03430 thrC threonine synthase 0.59 NOLOHH_05820 metB cystathionine gamma-synthase 0.96 15
Escherichia coli BL21 0.66 ECD_00004 L-threonine synthase 0.59 ECD_03825 cystathionine gamma-synthase, PLP-dependent 0.91 17
Escherichia coli ECRC62 0.66 BNILDI_08170 thrC threonine synthase 0.59 BNILDI_05715 metB cystathionine gamma-synthase 0.88 34
Escherichia coli ECRC101 0.66 MCAODC_01615 thrC threonine synthase 0.59 MCAODC_04175 metB cystathionine gamma-synthase 0.81 21
Escherichia coli ECRC98 0.66 JDDGAC_14695 thrC threonine synthase 0.59 JDDGAC_17300 metB cystathionine gamma-synthase 0.85 22
Escherichia coli ECRC100 0.66 OKFHMN_11100 thrC threonine synthase 0.59 OKFHMN_13675 metB cystathionine gamma-synthase 0.98 24
Escherichia coli ECRC102 0.66 NIAGMN_08950 thrC threonine synthase 0.59 NIAGMN_11430 metB cystathionine gamma-synthase 0.97 30
Escherichia coli BW25113 0.66 b0004 thrC threonine synthase (NCBI) 0.59 b3939 metB cystathionine gamma-synthase (NCBI) 0.80 63
Escherichia coli HS(pFamp)R (ATCC 700891) 0.66 OHPLBJKB_03656 Threonine synthase 0.59 OHPLBJKB_04111 Cystathionine gamma-synthase low > 74
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.66 GFF1080 Threonine synthase (EC 4.2.3.1) 0.59 GFF2323 Cystathionine gamma-synthase (EC 2.5.1.48) low > 78
Alteromonas macleodii MIT1002 0.62 MIT1002_03084 Threonine synthase 0.19 MIT1002_02266 Methionine gamma-lyase 0.94 27
Shewanella sp. ANA-3 0.60 Shewana3_1141 threonine synthase (RefSeq) 0.59 Shewana3_3614 cystathionine gamma-synthase (RefSeq) 0.91 33
Shewanella oneidensis MR-1 0.59 SO3413 thrC threonine synthase (NCBI ptt file) 0.57 SO4056 metB cystathionine gamma-synthase (NCBI ptt file) 0.95 24
Shewanella loihica PV-4 0.58 Shew_1081 threonine synthase (RefSeq) 0.56 Shew_0520 O-succinylhomoserine (thiol)-lyase (RefSeq) 0.97 21
Shewanella amazonensis SB2B 0.58 Sama_0907 threonine synthase (RefSeq) 0.59 Sama_3171 cystathionine gamma-synthase (RefSeq) 0.97 4
Bacteroides stercoris CC31F 0.43 HMPREF1181_RS00050 threonine synthase 0.25 HMPREF1181_RS05290 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 56
Phocaeicola vulgatus CL09T03C04 0.42 HMPREF1058_RS14730 threonine synthase 0.26 HMPREF1058_RS17635 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 67
Bacteroides thetaiotaomicron VPI-5482 0.42 BT2401 threonine synthase (NCBI ptt file) 0.25 BT2387 O-acetylhomoserine (thiol)-lyase (NCBI ptt file) low > 81
Bacteroides ovatus ATCC 8483 0.42 BACOVA_03023 threonine synthase 0.26 BACOVA_03030 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 96
Phocaeicola dorei CL03T12C01 0.42 ABI39_RS10440 threonine synthase 0.26 ABI39_RS13825 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 72
Parabacteroides merdae CL09T00C40 0.41 HMPREF1078_RS10395 threonine synthase 0.24 HMPREF1078_RS11020 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 61
Pedobacter sp. GW460-11-11-14-LB5 0.41 CA265_RS23465 threonine synthase 0.37 CA265_RS06375 cystathionine gamma-synthase low > 88
Echinicola vietnamensis KMM 6221, DSM 17526 0.40 Echvi_2002 threonine synthase 0.36 Echvi_2080 Cystathionine beta-lyases/cystathionine gamma-synthases low > 79
Mucilaginibacter yixingensis YX-36 DSM 26809 0.39 ABZR88_RS18960 threonine synthase 0.35 ABZR88_RS06685 cystathionine gamma-synthase — —
Cellulophaga baltica 18 0.39 M666_RS11605 threonine synthase 0.39 M666_RS03785 cystathionine gamma-synthase low > 67
Lysobacter sp. OAE881 0.31 ABIE51_RS17530 threonine synthase 0.52 ABIE51_RS16185 O-succinylhomoserine (thiol)-lyase 0.94 35
Xanthomonas campestris pv. campestris strain 8004 0.31 Xcc-8004.2954.1 Threonine synthase (EC 4.2.3.1) 0.53 Xcc-8004.1596.1 hypothetical protein low > 74
Rhizobium sp. OAE497 0.31 ABIE40_RS04230 threonine synthase 0.27 ABIE40_RS02340 O-succinylhomoserine sulfhydrylase — —
Sinorhizobium meliloti 1021 0.29 SMc00077 threonine synthase 0.47 SMc02595 cystathionine gamma-synthase — —
Agrobacterium fabrum C58 0.29 Atu0787 threonine synthase 0.27 Atu0432 O-succinylhomoserine sulfhydrylase — —
Rhodanobacter denitrificans FW104-10B01 0.29 LRK54_RS10355 threonine synthase 0.55 LRK54_RS05305 cystathionine gamma-synthase low > 59
Rhodanobacter denitrificans MT42 0.28 LRK55_RS09995 threonine synthase 0.56 LRK55_RS05085 cystathionine gamma-synthase low > 63
Phaeobacter inhibens DSM 17395 0.28 PGA1_c06310 threonine synthase ThrC 0.32 PGA1_c16600 methionine gamma-lyase MdeA — —
Azospirillum brasilense Sp245 0.28 AZOBR_RS10545 threonine synthase 0.27 AZOBR_RS11340 O-acetylhomoserine aminocarboxypropyltransferase — —
Rhodospirillum rubrum S1H 0.28 Rru_A3233 Threonine synthase (NCBI) 0.35 Rru_A0786 Cystathionine gamma-synthase (NCBI) — —
Rhodanobacter sp000427505 FW510-R12 0.27 LRK53_RS03155 threonine synthase 0.54 LRK53_RS04700 cystathionine gamma-synthase 0.61 54
Bosea sp. OAE506 0.27 ABIE41_RS22985 threonine synthase 0.27 ABIE41_RS19270 O-acetylhomoserine aminocarboxypropyltransferase — —
Dyella japonica UNC79MFTsu3.2 0.27 ABZR86_RS15975 threonine synthase (EC 4.2.3.1) (from data) 0.54 ABZR86_RS19030 cystathionine gamma-synthase 0.94 45
Xanthobacter sp. DMC5 0.27 GFF1319 Threonine synthase 0.25 GFF697 O-acetyl-L-homoserine sulfhydrylase — —
Azospirillum sp. SherDot2 0.27 MPMX19_00671 Threonine synthase 0.32 MPMX19_06514 L-methionine gamma-lyase — —
Rhodanobacter sp. FW510-T8 0.27 OKGIIK_13570 thrC threonine synthase 0.55 OKGIIK_01515 metB cystathionine gamma-synthase low > 53
Caulobacter crescentus NA1000 Δfur 0.27 CCNA_03510 threonine synthase 0.31 CCNA_03271 methionine gamma-lyase — —
Caulobacter crescentus NA1000 0.27 CCNA_03510 threonine synthase 0.31 CCNA_03271 methionine gamma-lyase — —
Dinoroseobacter shibae DFL-12 0.27 Dshi_1146 threonine synthase (RefSeq) 0.26 Dshi_1002 Cystathionine gamma-synthase (RefSeq) — —
Marinobacter adhaerens HP15 0.26 HP15_765 threonine synthase 0.27 HP15_1820 methionine gamma-lyase — —
Pseudomonas aeruginosa PA14 0.26 IKLFDK_19070 threonine synthase 0.37 IKLFDK_23420 cystathionine gamma-synthase low > 100
Pseudomonas syringae pv. syringae B728a 0.25 Psyr_1291 L-threonine synthase 0.30 Psyr_1669 O-succinylhomoserine sulfhydrylase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.25 Psyr_1291 L-threonine synthase 0.30 Psyr_1669 O-succinylhomoserine sulfhydrylase — —
Pseudomonas fluorescens FW300-N2E3 0.25 AO353_04350 threonine synthase 0.38 AO353_23295 cystathionine beta-lyase — —
Pseudomonas putida KT2440 0.25 PP_1471 Threonine synthase 0.34 PP_4594 putative Cystathionine gamma-synthase — —
Pseudomonas sp. S08-1 0.25 OH686_17765 threonine synthase 0.31 OH686_04415 O-succinylhomoserine sulfhydrylase low > 80
Rhodopseudomonas palustris CGA009 0.25 TX73_004325 threonine synthase 0.30 TX73_012185 PLP-dependent aspartate aminotransferase family protein — —
Pseudomonas sp. SVBP6 0.25 COO64_RS04940 thrC threonine synthase 0.37 COO64_RS14890 cystathionine gamma-synthase — —
Pseudomonas fluorescens FW300-N2E2 0.25 Pf6N2E2_3142 Threonine synthase (EC 4.2.3.1) 0.30 Pf6N2E2_77 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) — —
Pseudomonas fluorescens FW300-N2C3 0.25 AO356_06370 threonine synthase 0.30 AO356_21470 O-succinylhomoserine sulfhydrylase — —
Pseudomonas sp. BP01 0.25 JOY50_RS11715 thrC threonine synthase 0.34 JOY50_RS01570 PLP-dependent aspartate aminotransferase family protein — —
Pseudomonas stutzeri RCH2 0.25 Psest_3125 threonine synthase 0.32 Psest_2578 O-succinylhomoserine sulfhydrylase — —
Pseudomonas simiae WCS417 0.25 PS417_22880 threonine synthase 0.32 PS417_11735 methionine gamma-lyase — —
Pseudomonas fluorescens SBW25 0.25 PFLU_RS24545 threonine synthase 0.36 PFLU_RS16625 cystathionine gamma-synthase low > 109
Pseudomonas fluorescens SBW25-INTG 0.25 PFLU_RS24545 threonine synthase 0.36 PFLU_RS16625 cystathionine gamma-synthase — —
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_3014 Threonine synthase (EC 4.2.3.1) 0.38 Pf1N1B4_4890 Cystathionine gamma-lyase (EC 4.4.1.1) — —
Pseudomonas lactucae CFBP13502 0.25 GEMAOFIL_04726 Threonine synthase 0.37 GEMAOFIL_02861 Cystathionine beta-lyase low > 93
Sphingobium sp. HT1-2 0.25 GFF4764 Threonine synthase (EC 4.2.3.1) 0.27 GFF3455 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.78 39
Pseudomonas segetis P6 0.25 MPMX49_01578 Threonine synthase 0.33 MPMX49_01099 Cystathionine beta-lyase low > 75
Pseudomonas sp. RS175 0.25 PFR28_00334 Threonine synthase 0.30 PFR28_02810 O-succinylhomoserine sulfhydrylase — —
Pseudomonas sp. DMC3 0.25 GFF1990 Threonine synthase 0.38 GFF3060 Cystathionine beta-lyase — —
Pseudomonas fluorescens GW456-L13 0.24 PfGW456L13_1724 Threonine synthase (EC 4.2.3.1) 0.30 PfGW456L13_3934 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) — —
Ralstonia sp. UNC404CL21Col 0.24 ABZR87_RS05865 threonine synthase 0.27 ABZR87_RS17575 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme low > 80
Brevundimonas sp. GW460-12-10-14-LB2 0.24 A4249_RS00020 threonine synthase 0.54 A4249_RS16160 cystathionine gamma-synthase 0.99 19
Magnetospirillum magneticum AMB-1 0.24 AMB_RS17140 threonine synthase 0.27 AMB_RS21365 O-succinylhomoserine sulfhydrylase — —
Methylophilus sp. DMC18 0.23 GFF1164 Threonine synthase 0.28 GFF412 O-acetyl-L-homoserine sulfhydrylase — —
Castellaniella sp019104865 MT123 0.23 ABCV34_RS02300 threonine synthase 0.30 ABCV34_RS15785 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.23 GFF3936 Threonine synthase (EC 4.2.3.1) 0.29 GFF301 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) — —
Sphingomonas koreensis DSMZ 15582 0.23 Ga0059261_1999 threonine synthase 0.26 Ga0059261_3194 O-acetylhomoserine sulfhydrylase (EC:2.5.1.49) (from data) 0.89 56
Bifidobacterium breve UCC2003 0.23 BBR_RS14070 threonine synthase (EC 4.2.3.1) (from data) 0.35 BBR_RS13145 cystathionine gamma-synthase low > 34
Variovorax sp. SCN45 0.22 GFF2800 Threonine synthase (EC 4.2.3.1) 0.28 GFF3088 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) — —
Dechlorosoma suillum PS 0.22 Dsui_2904 threonine synthase 0.35 Dsui_2042 cystathionine beta-lyase/cystathionine gamma-synthase — —
Paraburkholderia graminis OAS925 0.22 ABIE53_002027 threonine synthase 0.26 ABIE53_004817 O-succinylhomoserine sulfhydrylase — —
Variovorax sp. OAS795 0.22 ABID97_RS10895 threonine synthase 0.27 ABID97_RS21630 O-succinylhomoserine sulfhydrylase — —
Burkholderia phytofirmans PsJN 0.21 BPHYT_RS08960 threonine synthase 0.26 BPHYT_RS33835 O-succinylhomoserine sulfhydrylase 0.58 94
Paraburkholderia bryophila 376MFSha3.1 0.21 H281DRAFT_00811 L-threonine synthase 0.26 H281DRAFT_06059 O-succinylhomoserine sulfhydrylase — —
Acidovorax sp. GW101-3H11 0.21 Ac3H11_1505 Threonine synthase (EC 4.2.3.1) 0.31 Ac3H11_34 Methionine gamma-lyase (EC 4.4.1.11) — —
Paraburkholderia sabiae LMG 24235 0.21 QEN71_RS22400 threonine synthase 0.25 QEN71_RS17685 O-succinylhomoserine sulfhydrylase low > 153
Herbaspirillum seropedicae SmR1 0.20 HSERO_RS10470 threonine synthase 0.22 HSERO_RS18310 O-acetylhomoserine aminocarboxypropyltransferase — —
Cupriavidus basilensis FW507-4G11 0.20 RR42_RS12535 threonine synthase 0.26 RR42_RS06465 O-acetylhomoserine aminocarboxypropyltransferase — —
Ralstonia solanacearum GMI1000 0.19 RS_RS06660 threonine synthase 0.25 RS_RS07865 O-acetylhomoserine aminocarboxypropyltransferase — —
Ralstonia solanacearum PSI07 0.18 RPSI07_RS17485 threonine synthase 0.25 RPSI07_RS15620 O-acetylhomoserine aminocarboxypropyltransferase — —
Ralstonia solanacearum IBSBF1503 0.18 RALBFv3_RS15880 threonine synthase 0.25 RALBFv3_RS01870 O-acetylhomoserine aminocarboxypropyltransferase — —
Ralstonia solanacearum UW163 0.18 UW163_RS13325 threonine synthase 0.25 UW163_RS15180 O-acetylhomoserine aminocarboxypropyltransferase — —

Not shown: 0 genomes with orthologs for CSW01_11965 only; 7 genomes with orthologs for CSW01_13550 only