Conservation of cofitness between CSW01_00290 and CSW01_12265 in Vibrio cholerae E7946 ATCC 55056

112 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_00290 gamma carbonic anhydrase family protein 1.0 CSW01_12265 carboxylating nicotinate-nucleotide diphosphorylase 0.83 4
Shewanella amazonensis SB2B 0.70 Sama_0054 carbonic anhydrase (RefSeq) 0.63 Sama_0371 nicotinate-nucleotide diphosphorylase (carboxylating) (RefSeq) — —
Shewanella sp. ANA-3 0.69 Shewana3_0045 carbonic anhydrase (RefSeq) 0.59 Shewana3_0422 nicotinate-nucleotide pyrophosphorylase [carboxylating] (RefSeq) — —
Pantoea agglomerans CFBP13505 P0401 0.69 PagCFBP13505_RS22570 gamma carbonic anhydrase family protein 0.56 PagCFBP13505_RS13155 carboxylating nicotinate-nucleotide diphosphorylase low > 74
Alteromonas macleodii MIT1002 0.68 MIT1002_00030 carnitine operon protein CaiE 0.53 MIT1002_03008 Nicotinate-nucleotide pyrophosphorylase [carboxylating] — —
Pseudomonas sp. RS175 0.68 PFR28_04700 Protein YrdA 0.55 PFR28_00098 Nicotinate-nucleotide pyrophosphorylase [carboxylating] low > 88
Pseudomonas fluorescens FW300-N2E2 0.68 Pf6N2E2_4090 carbonic anhydrase, family 3 0.53 Pf6N2E2_3346 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) low > 103
Shewanella loihica PV-4 0.67 Shew_3725 carbonic anhydrase (RefSeq) 0.59 Shew_3435 nicotinate-nucleotide pyrophosphorylase (RefSeq) — —
Pseudomonas fluorescens FW300-N2C3 0.67 AO356_11115 anhydrase 0.53 AO356_07370 nicotinate-nucleotide pyrophosphorylase low > 104
Pseudomonas segetis P6 0.67 MPMX49_00360 Protein YrdA 0.54 MPMX49_03901 Nicotinate-nucleotide pyrophosphorylase [carboxylating] — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.67 GFF2399 carbonic anhydrase, family 3 0.60 GFF130 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) low > 78
Pseudomonas aeruginosa PUPa3 0.67 DQ20_RS31165 gamma carbonic anhydrase family protein 0.51 DQ20_RS56315 nadC;go_function=nicotinate-nucleotide carboxylating nicotinate-nucleotide diphosphorylase low > 101
Klebsiella michiganensis M5al 0.67 BWI76_RS25635 gamma carbonic anhydrase family protein 0.57 BWI76_RS04845 nicotinate-nucleotide pyrophosphorylase low > 92
Pseudomonas aeruginosa MRSN321 0.67 DY961_RS26595 gamma carbonic anhydrase family protein 0.51 DY961_RS23850 nadC;go_function=nicotinate-nucleotide carboxylating nicotinate-nucleotide diphosphorylase low > 100
Pseudomonas aeruginosa PA14 0.67 IKLFDK_25220 gamma carbonic anhydrase family protein 0.51 IKLFDK_01460 carboxylating nicotinate-nucleotide diphosphorylase low > 98
Pseudomonas fluorescens SBW25-INTG 0.67 PFLU_RS00235 gamma carbonic anhydrase family protein 0.54 PFLU_RS03970 carboxylating nicotinate-nucleotide diphosphorylase low > 109
Pseudomonas fluorescens FW300-N2E3 0.67 AO353_10770 anhydrase 0.55 AO353_05520 nicotinate-nucleotide pyrophosphorylase low > 101
Pseudomonas fluorescens SBW25 0.67 PFLU_RS00235 gamma carbonic anhydrase family protein 0.54 PFLU_RS03970 carboxylating nicotinate-nucleotide diphosphorylase low > 109
Enterobacter sp. TBS_079 0.66 MPMX20_04187 Protein YrdA 0.57 MPMX20_00800 Nicotinate-nucleotide pyrophosphorylase [carboxylating] low > 85
Pseudomonas simiae WCS417 0.66 PS417_00240 anhydrase 0.54 PS417_03925 nicotinate-nucleotide pyrophosphorylase 0.16 39
Pseudomonas fluorescens FW300-N1B4 0.66 Pf1N1B4_1843 carbonic anhydrase, family 3 0.55 Pf1N1B4_1153 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) low > 87
Serratia liquefaciens MT49 0.66 IAI46_23235 gamma carbonic anhydrase family protein 0.60 IAI46_03530 carboxylating nicotinate-nucleotide diphosphorylase low > 87
Pseudomonas lactucae CFBP13502 0.66 GEMAOFIL_00253 Protein YrdA 0.55 GEMAOFIL_00989 Nicotinate-nucleotide pyrophosphorylase [carboxylating] low > 96
Rahnella sp. WP5 0.66 EX31_RS15945 gamma carbonic anhydrase family protein 0.60 EX31_RS03515 carboxylating nicotinate-nucleotide diphosphorylase low > 89
Pseudomonas sp. DMC3 0.66 GFF664 Protein YrdA 0.52 GFF4996 Nicotinate-nucleotide pyrophosphorylase [carboxylating] low > 89
Pseudomonas putida KT2440 0.66 PP_0095 putative enzyme of unknown function 0.50 PP_0787 quinolinate phosphoribosyltransferase (decarboxylating) monomer low > 96
Pseudomonas sp. SVBP6 0.66 COO64_RS02330 gamma carbonic anhydrase family protein 0.53 COO64_RS03520 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 93
Pseudomonas sp. S08-1 0.66 OH686_12365 Protein YrdA 0.51 OH686_16520 nicotinate-nucleotide diphosphorylase (carboxylating) low > 80
Pseudomonas orientalis W4I3 0.65 QF045_RS03185 gamma carbonic anhydrase family protein 0.55 QF045_RS06900 carboxylating nicotinate-nucleotide diphosphorylase low > 93
Escherichia coli ECOR27 0.65 NOLOHH_09365 yrdA Protein YrdA 0.57 NOLOHH_02875 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 76
Pseudomonas fluorescens GW456-L13 0.65 PfGW456L13_625 carbonic anhydrase, family 3 0.52 PfGW456L13_5082 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) low > 87
Escherichia coli ECRC101 0.65 MCAODC_08095 yrdA Protein YrdA 0.57 MCAODC_01045 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.65 OHPLBJKB_00424 Protein YrdA 0.57 OHPLBJKB_03552 Nicotinate-nucleotide pyrophosphorylase [carboxylating] low > 74
Escherichia coli ECRC100 0.65 OKFHMN_17575 yrdA Protein YrdA 0.57 OKFHMN_10530 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 79
Escherichia coli ECRC99 0.65 KEDOAH_10575 yrdA Protein YrdA 0.57 KEDOAH_17625 nadC carboxylating nicotinate-nucleotide diphosphorylase — —
Escherichia coli ECOR38 0.65 HEPCGN_16395 yrdA Protein YrdA 0.56 HEPCGN_08510 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 88
Escherichia coli ECRC98 0.65 JDDGAC_21195 yrdA Protein YrdA 0.57 JDDGAC_14125 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 87
Escherichia coli BW25113 0.65 b3279 yrdA putative transferase (VIMSS) 0.57 b0109 nadC nicotinate-nucleotide pyrophosphorylase (NCBI) low > 76
Escherichia coli ECRC62 0.65 BNILDI_02155 yrdA Protein YrdA 0.57 BNILDI_08735 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 75
Escherichia coli ECRC102 0.65 NIAGMN_15335 yrdA Protein YrdA 0.57 NIAGMN_08380 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 80
Pseudomonas stutzeri RCH2 0.65 Psest_4319 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily 0.53 Psest_0718 nicotinate-nucleotide pyrophosphorylase low > 67
Enterobacter asburiae PDN3 0.65 EX28DRAFT_0048 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily 0.57 EX28DRAFT_3702 nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) 0.50 57
Pseudomonas sp. BP01 0.65 JOY50_RS21250 gamma carbonic anhydrase family protein 0.51 JOY50_RS19345 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 84
Escherichia coli Nissle 1917 0.65 ECOLIN_RS18830 gamma carbonic anhydrase family protein 0.57 ECOLIN_RS00585 carboxylating nicotinate-nucleotide diphosphorylase low > 55
Escherichia fergusonii Becca 0.65 EFB2_00544 Protein YrdA 0.57 EFB2_03940 Nicotinate-nucleotide pyrophosphorylase [carboxylating] low > 86
Escherichia coli BL21 0.65 ECD_03130 bacterial transferase hexapeptide domain protein 0.57 ECD_00108 quinolinate phosphoribosyltransferase low > 61
Dickeya dadantii 3937 0.64 DDA3937_RS19090 gamma carbonic anhydrase family protein 0.62 DDA3937_RS17955 carboxylating nicotinate-nucleotide diphosphorylase 0.67 15
Pantoea sp. MT58 0.64 IAI47_02325 gamma carbonic anhydrase family protein 0.56 IAI47_15845 carboxylating nicotinate-nucleotide diphosphorylase low > 76
Klebsiella pneumoniae MKP103 0.64 KDGMDA_06505 gamma carbonic anhydrase family protein 0.62 KDGMDA_13080 carboxylating nicotinate-nucleotide diphosphorylase low > 95
Erwinia tracheiphila HP pepo 2.2 0.64 IJEDHG_12515 Gamma carbonic anhydrase family protein 0.55 IJEDHG_05835 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 61
Erwinia tracheiphila SCR3 0.64 LU632_RS22435 gamma carbonic anhydrase family protein 0.55 LU632_RS03040 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 73
Dickeya dianthicola 67-19 0.63 HGI48_RS19180 gamma carbonic anhydrase family protein 0.63 HGI48_RS17890 carboxylating nicotinate-nucleotide diphosphorylase low > 71
Dickeya dianthicola ME23 0.63 DZA65_RS20305 gamma carbonic anhydrase family protein 0.63 DZA65_RS19035 carboxylating nicotinate-nucleotide diphosphorylase 0.61 7
Pseudomonas syringae pv. syringae B728a ΔmexB 0.63 Psyr_0044 transferase hexapeptide repeat protein 0.55 Psyr_0815 nicotinate-nucleotide pyrophosphorylase (carboxylating) — —
Pectobacterium carotovorum WPP14 0.63 HER17_RS02260 gamma carbonic anhydrase family protein 0.61 HER17_RS03250 carboxylating nicotinate-nucleotide diphosphorylase low > 75
Pseudomonas syringae pv. syringae B728a 0.63 Psyr_0044 transferase hexapeptide repeat protein 0.55 Psyr_0815 nicotinate-nucleotide pyrophosphorylase (carboxylating) low > 86
Cupriavidus basilensis FW507-4G11 0.61 RR42_RS06425 anhydrase 0.42 RR42_RS17015 nicotinate-nucleotide pyrophosphorylase low > 128
Acinetobacter radioresistens SK82 0.59 MPMX26_01050 Protein YrdA 0.48 MPMX26_00042 Nicotinate-nucleotide pyrophosphorylase [carboxylating] low > 36
Marinobacter adhaerens HP15 0.58 HP15_3758 transferase hexapeptide repeat protein 0.52 HP15_1305 nicotinate-nucleotide pyrophosphorylase — —
Acinetobacter baumannii LAC-4 0.56 RR41_RS05325 gamma carbonic anhydrase family protein 0.48 RR41_RS18680 carboxylating nicotinate-nucleotide diphosphorylase low > 55
Kangiella aquimarina DSM 16071 0.55 B158DRAFT_0464 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily 0.51 B158DRAFT_2135 nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) — —
Dechlorosoma suillum PS 0.51 Dsui_2380 isoleucine patch superfamily enzyme, carbonic anhydrase/acetyltransferase 0.48 Dsui_2901 nicotinate-nucleotide pyrophosphorylase — —
Dyella japonica UNC79MFTsu3.2 0.50 ABZR86_RS14950 gamma carbonic anhydrase family protein 0.48 ABZR86_RS09850 carboxylating nicotinate-nucleotide diphosphorylase low > 74
Rhodanobacter sp000427505 FW510-R12 0.49 LRK53_RS02385 gamma carbonic anhydrase family protein 0.38 LRK53_RS14805 carboxylating nicotinate-nucleotide diphosphorylase low > 59
Acidovorax sp. GW101-3H11 0.49 Ac3H11_4230 carbonic anhydrase, family 3 0.41 Ac3H11_3838 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) low > 79
Rhodanobacter denitrificans MT42 0.48 LRK55_RS08375 gamma carbonic anhydrase family protein 0.46 LRK55_RS13510 carboxylating nicotinate-nucleotide diphosphorylase low > 63
Rhodanobacter denitrificans FW104-10B01 0.48 LRK54_RS08610 gamma carbonic anhydrase family protein 0.46 LRK54_RS13795 carboxylating nicotinate-nucleotide diphosphorylase low > 59
Lysobacter sp. OAE881 0.47 ABIE51_RS01770 gamma carbonic anhydrase family protein 0.37 ABIE51_RS15405 carboxylating nicotinate-nucleotide diphosphorylase low > 62
Xanthomonas campestris pv. campestris strain 8004 0.47 Xcc-8004.456.1 carbonic anhydrase, family 3 0.36 Xcc-8004.2009.1 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) low > 74
Rhodospirillum rubrum S1H 0.43 Rru_A2420 transferase hexapeptide repeat (NCBI) 0.32 Rru_A1432 Nicotinate-nucleotide pyrophosphorylase (NCBI) low > 58
Azospirillum sp. SherDot2 0.42 MPMX19_03844 Protein YrdA 0.34 MPMX19_05672 putative nicotinate-nucleotide pyrophosphorylase [carboxylating] — —
Magnetospirillum magneticum AMB-1 0.42 AMB_RS09070 gamma carbonic anhydrase family protein 0.39 AMB_RS19655 nicotinate-nucleotide diphosphorylase (carboxylating) — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.41 ABZR88_RS20625 gamma carbonic anhydrase family protein 0.32 ABZR88_RS15695 carboxylating nicotinate-nucleotide diphosphorylase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.41 CA264_14360 gamma carbonic anhydrase family protein 0.31 CA264_16940 nicotinate-nucleotide diphosphorylase (carboxylating) — —
Pedobacter sp. GW460-11-11-14-LB5 0.39 CA265_RS21190 gamma carbonic anhydrase family protein 0.32 CA265_RS14530 nicotinate-nucleotide diphosphorylase (carboxylating) low > 88
Variovorax sp. SCN45 0.39 GFF2764 Carbonic anhydrase-like protein MJ0304 0.38 GFF2574 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) low > 127
Sphingobium sp. HT1-2 0.39 GFF1600 Carbonic anhydrase, gamma class (EC 4.2.1.1) 0.30 GFF243 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) low > 95
Cellulophaga baltica 18 0.38 M666_RS07850 gamma carbonic anhydrase family protein 0.27 M666_RS17945 carboxylating nicotinate-nucleotide diphosphorylase — —
Variovorax sp. OAS795 0.37 ABID97_RS20225 gamma carbonic anhydrase family protein 0.39 ABID97_RS07410 carboxylating nicotinate-nucleotide diphosphorylase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.36 Echvi_2335 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily 0.31 Echvi_1158 nicotinate-nucleotide pyrophosphorylase low > 79
Caulobacter crescentus NA1000 Δfur 0.36 CCNA_02726 gamma carbonic anhydrase family protein 0.33 CCNA_03009 nicotinate-nucleotide pyrophosphorylase — —
Phocaeicola dorei CL03T12C01 0.36 ABI39_RS03850 gamma carbonic anhydrase family protein 0.35 ABI39_RS11900 carboxylating nicotinate-nucleotide diphosphorylase — —
Caulobacter crescentus NA1000 0.36 CCNA_02726 gamma carbonic anhydrase family protein 0.33 CCNA_03009 nicotinate-nucleotide pyrophosphorylase — —
Sphingomonas koreensis DSMZ 15582 0.36 Ga0059261_0268 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily 0.31 Ga0059261_0061 nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.36 GFF5446 carbonic anhydrase, family 3 0.44 GFF1217 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) — —
Phocaeicola vulgatus CL09T03C04 0.36 HMPREF1058_RS09460 gamma carbonic anhydrase family protein 0.35 HMPREF1058_RS15940 carboxylating nicotinate-nucleotide diphosphorylase — —
Bacteroides thetaiotaomicron VPI-5482 0.35 BT2744 acetyltransferase (NCBI ptt file) 0.34 BT1560 nicotinate-nucleotide pyrophosphorylase (NCBI ptt file) — —
Castellaniella sp019104865 MT123 0.35 ABCV34_RS13300 gamma carbonic anhydrase family protein 0.42 ABCV34_RS03695 carboxylating nicotinate-nucleotide diphosphorylase low > 48
Bacteroides ovatus ATCC 8483 0.34 BACOVA_01053 hexapeptide transferase family protein 0.34 BACOVA_04303 nicotinate-nucleotide diphosphorylase (carboxylating) low > 96
Parabacteroides merdae CL09T00C40 0.34 HMPREF1078_RS13110 gamma carbonic anhydrase family protein 0.33 HMPREF1078_RS16725 carboxylating nicotinate-nucleotide diphosphorylase — —
Herbaspirillum seropedicae SmR1 0.34 HSERO_RS08610 anhydrase 0.42 HSERO_RS11070 nicotinate-nucleotide pyrophosphorylase low > 78
Bacteroides stercoris CC31F 0.34 HMPREF1181_RS00640 gamma carbonic anhydrase family protein 0.35 HMPREF1181_RS10745 carboxylating nicotinate-nucleotide diphosphorylase — —
Ralstonia sp. UNC404CL21Col 0.34 ABZR87_RS10490 gamma carbonic anhydrase family protein 0.44 ABZR87_RS00350 carboxylating nicotinate-nucleotide diphosphorylase low > 80
Rhizobium sp. OAE497 0.34 ABIE40_RS10925 gamma carbonic anhydrase family protein 0.34 ABIE40_RS23265 carboxylating nicotinate-nucleotide diphosphorylase low > 107
Burkholderia phytofirmans PsJN 0.33 BPHYT_RS12655 anhydrase 0.44 BPHYT_RS15645 nicotinate-nucleotide pyrophosphorylase — —
Paraburkholderia graminis OAS925 0.33 ABIE53_002757 carbonic anhydrase/acetyltransferase-like protein (isoleucine patch superfamily) 0.43 ABIE53_003293 nicotinate-nucleotide pyrophosphorylase (carboxylating) — —
Paraburkholderia sabiae LMG 24235 0.33 QEN71_RS12115 gamma carbonic anhydrase family protein 0.44 QEN71_RS03065 carboxylating nicotinate-nucleotide diphosphorylase low > 153
Sinorhizobium meliloti 1021 0.33 SMc04241 acetyltransferase 0.30 SMc02598 nicotinate-nucleotide pyrophosphorylase carboxylating protein low > 103
Paraburkholderia bryophila 376MFSha3.1 0.33 H281DRAFT_00501 Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily 0.41 H281DRAFT_04070 nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.54 18
Rhodopseudomonas palustris CGA009 0.32 TX73_017715 gamma carbonic anhydrase family protein 0.37 TX73_005415 carboxylating nicotinate-nucleotide diphosphorylase — —
Phaeobacter inhibens DSM 17395 0.32 PGA1_c15820 putative phenylacetic acid degradation protein 0.32 PGA1_c27810 nicotinate-nucleotide pyrophosphorylase low > 62
Ralstonia solanacearum PSI07 0.32 RPSI07_RS18530 gamma carbonic anhydrase family protein 0.45 RPSI07_RS12655 nicotinate-nucleotide diphosphorylase (carboxylating) 0.42 8
Ralstonia solanacearum IBSBF1503 0.31 RALBFv3_RS14830 gamma carbonic anhydrase family protein 0.44 RALBFv3_RS04730 nicotinate-nucleotide diphosphorylase (carboxylating) — —
Ralstonia solanacearum GMI1000 0.31 RS_RS05640 gamma carbonic anhydrase family protein 0.42 RS_RS12290 nicotinate-nucleotide diphosphorylase (carboxylating) low > 80
Ralstonia solanacearum UW163 0.31 UW163_RS12300 gamma carbonic anhydrase family protein 0.44 UW163_RS08940 nicotinate-nucleotide diphosphorylase (carboxylating) — —
Xanthobacter sp. DMC5 0.31 GFF4616 Protein YrdA 0.31 GFF1521 putative nicotinate-nucleotide pyrophosphorylase [carboxylating] — —
Methanococcus maripaludis S2 0.30 MMP_RS00295 gamma carbonic anhydrase family protein 0.22 MMP_RS04560 carboxylating nicotinate-nucleotide diphosphorylase — —
Methanococcus maripaludis JJ 0.30 MMJJ_RS05190 gamma carbonic anhydrase family protein 0.21 MMJJ_RS00575 carboxylating nicotinate-nucleotide diphosphorylase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.29 A4249_RS02210 gamma carbonic anhydrase family protein 0.32 A4249_RS00635 carboxylating nicotinate-nucleotide diphosphorylase low > 48
Synechococcus elongatus PCC 7942 0.29 Synpcc7942_1961 fbp ferripyochelin binding protein 0.28 Synpcc7942_0951 nadC nicotinate-nucleotide pyrophosphorylase low > 38
Agrobacterium fabrum C58 0.29 Atu1517 hypothetical protein 0.33 Atu4096 nicotinate-nucleotide pyrophosphorylase low > 89
Bosea sp. OAE506 0.27 ABIE41_RS14005 gamma carbonic anhydrase family protein 0.36 ABIE41_RS02500 carboxylating nicotinate-nucleotide diphosphorylase — —
Mycobacterium tuberculosis H37Rv 0.25 Rv3525c Possible siderophore-binding protein 0.32 Rv1596 Probable nicotinate-nucleotide pyrophosphatase NadC — —

Not shown: 5 genomes with orthologs for CSW01_00290 only; 6 genomes with orthologs for CSW01_12265 only