Conservation of cofitness between CSW01_12725 and CSW01_01520 in Vibrio cholerae E7946 ATCC 55056

103 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_12725 aspartate carbamoyltransferase 1.0 CSW01_01520 acetyl-coenzyme A synthetase 0.67 20
Klebsiella pneumoniae MKP103 0.76 KDGMDA_11465 aspartate carbamoyltransferase 0.77 KDGMDA_10565 acetate--CoA ligase low > 95
Klebsiella michiganensis M5al 0.76 BWI76_RS02995 aspartate carbamoyltransferase 0.77 BWI76_RS02095 acetyl-coenzyme A synthetase low > 92
Serratia liquefaciens MT49 0.76 IAI46_02275 aspartate carbamoyltransferase 0.79 IAI46_01405 acetate--CoA ligase low > 86
Escherichia coli ECOR27 0.76 NOLOHH_04125 pyrB aspartate carbamoyltransferase 0.77 NOLOHH_05080 acs acetate--CoA ligase low > 76
Escherichia coli Nissle 1917 0.75 ECOLIN_RS24625 aspartate carbamoyltransferase 0.76 ECOLIN_RS23550 acetate--CoA ligase low > 55
Escherichia coli BW25113 0.75 b4245 pyrB aspartate carbamoyltransferase catalytic subunit (NCBI) 0.77 b4069 acs acetyl-coenzyme A synthetase (NCBI) low > 76
Escherichia fergusonii Becca 0.75 EFB2_04288 Aspartate carbamoyltransferase catalytic subunit 0.77 EFB2_04520 Acetyl-coenzyme A synthetase low > 86
Escherichia coli ECRC62 0.75 BNILDI_07385 pyrB aspartate carbamoyltransferase 0.77 BNILDI_06445 acs acetate--CoA ligase low > 75
Escherichia coli ECOR38 0.75 HEPCGN_10060 pyrB aspartate carbamoyltransferase 0.77 HEPCGN_11455 acs acetate--CoA ligase low > 88
Escherichia coli BL21 0.75 ECD_04113 aspartate carbamoyltransferase, catalytic subunit 0.77 ECD_03941 acetyl-CoA synthetase low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 0.75 OHPLBJKB_03789 Aspartate carbamoyltransferase catalytic subunit 0.77 OHPLBJKB_03971 Acetyl-coenzyme A synthetase low > 74
Escherichia coli ECRC100 0.75 OKFHMN_11865 pyrB aspartate carbamoyltransferase 0.77 OKFHMN_12830 acs acetate--CoA ligase low > 79
Escherichia coli ECRC98 0.75 JDDGAC_15505 pyrB aspartate carbamoyltransferase 0.77 JDDGAC_16465 acs acetate--CoA ligase low > 87
Escherichia coli ECRC99 0.75 KEDOAH_16290 pyrB aspartate carbamoyltransferase 0.77 KEDOAH_15320 acs acetate--CoA ligase — —
Escherichia coli ECRC102 0.75 NIAGMN_09715 pyrB aspartate carbamoyltransferase 0.77 NIAGMN_10675 acs acetate--CoA ligase low > 80
Escherichia coli ECRC101 0.75 MCAODC_02370 pyrB aspartate carbamoyltransferase 0.77 MCAODC_03340 acs acetate--CoA ligase low > 88
Dickeya dianthicola ME23 0.75 DZA65_RS01970 aspartate carbamoyltransferase 0.77 DZA65_RS03695 acetate--CoA ligase low > 75
Erwinia amylovora T8 0.75 OLJFJH_07330 aspartate carbamoyltransferase 0.77 OLJFJH_03335 acetate--CoA ligase low > 58
Dickeya dianthicola 67-19 0.75 HGI48_RS01900 aspartate carbamoyltransferase 0.77 HGI48_RS03580 acetate--CoA ligase low > 71
Dickeya dadantii 3937 0.75 DDA3937_RS01925 aspartate carbamoyltransferase 0.77 DDA3937_RS03480 acetate--CoA ligase low > 74
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.75 GFF930 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.76 GFF1452 Acetyl-coenzyme A synthetase (EC 6.2.1.1) low > 78
Pantoea agglomerans CFBP13505 P0401 0.75 PagCFBP13505_RS08955 aspartate carbamoyltransferase 0.77 PagCFBP13505_RS21040 acetate--CoA ligase low > 74
Erwinia tracheiphila HP pepo 2.2 0.74 IJEDHG_14060 pyrB aspartate carbamoyltransferase 0.77 IJEDHG_11295 acs acetate--CoA ligase low > 61
Enterobacter asburiae PDN3 0.74 EX28DRAFT_3446 aspartate carbamoyltransferase (EC 2.1.3.2) 0.77 EX28DRAFT_4232 acetate--CoA ligase — —
Erwinia tracheiphila SCR3 0.74 LU632_RS20950 pyrB aspartate carbamoyltransferase 0.77 LU632_RS23305 acs acetate--CoA ligase low > 74
Pantoea sp. MT58 0.74 IAI47_16860 aspartate carbamoyltransferase 0.77 IAI47_17715 acetate--CoA ligase low > 76
Enterobacter sp. TBS_079 0.74 MPMX20_00544 Aspartate carbamoyltransferase catalytic subunit 0.77 MPMX20_00291 Acetyl-coenzyme A synthetase low > 85
Rahnella sp. WP5 0.74 EX31_RS12785 aspartate carbamoyltransferase 0.78 EX31_RS09040 acetate--CoA ligase low > 89
Pectobacterium carotovorum WPP14 0.73 HER17_RS19510 aspartate carbamoyltransferase 0.78 HER17_RS17630 acetate--CoA ligase low > 75
Bacteroides stercoris CC31F 0.51 HMPREF1181_RS14990 aspartate carbamoyltransferase 0.13 HMPREF1181_RS03430 AMP-binding protein low > 56
Parabacteroides merdae CL09T00C40 0.51 HMPREF1078_RS01350 aspartate carbamoyltransferase 0.13 HMPREF1078_RS10645 AMP-binding protein — —
Bacteroides thetaiotaomicron VPI-5482 0.50 BT0742 aspartate carbamoyltransferase catalytic chain (NCBI ptt file) 0.14 BT3755 acetyl-coenzyme A synthetase (NCBI ptt file) — —
Phocaeicola vulgatus CL09T03C04 0.50 HMPREF1058_RS03820 aspartate carbamoyltransferase 0.12 HMPREF1058_RS08765 AMP-binding protein — —
Methanococcus maripaludis S2 0.44 MMP_RS08545 aspartate carbamoyltransferase 0.42 MMP_RS00845 acetate--CoA ligase — —
Methanococcus maripaludis JJ 0.44 MMJJ_RS05825 aspartate carbamoyltransferase 0.43 MMJJ_RS04645 acetate--CoA ligase — —
Kangiella aquimarina DSM 16071 0.34 B158DRAFT_0021 aspartate carbamoyltransferase (EC 2.1.3.2) 0.65 B158DRAFT_0063 acetate--CoA ligase — —
Shewanella oneidensis MR-1 0.34 SO1301 pyrB aspartate carbamoyltransferase (NCBI ptt file) 0.73 SO2743 acs acetyl-coenzyme A synthetase (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.34 Shewana3_3070 aspartate carbamoyltransferase (RefSeq) 0.73 Shewana3_2523 acetyl-CoA synthetase (RefSeq) low > 73
Shewanella loihica PV-4 0.33 Shew_1013 aspartate carbamoyltransferase (RefSeq) 0.73 Shew_1533 acetyl-CoA synthetase (RefSeq) low > 60
Alteromonas macleodii MIT1002 0.33 MIT1002_00423 Aspartate carbamoyltransferase catalytic chain 0.67 MIT1002_03516 Acetyl-coenzyme A synthetase low > 70
Shewanella amazonensis SB2B 0.33 Sama_0840 aspartate carbamoyltransferase (RefSeq) 0.73 Sama_2079 acetyl-CoA synthetase (RefSeq) low > 62
Xanthomonas campestris pv. campestris strain 8004 0.25 Xcc-8004.1722.1 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.64 Xcc-8004.5157.1 Acetyl-coenzyme A synthetase (EC 6.2.1.1) — —
Pseudomonas sp. RS175 0.25 PFR28_04237 Aspartate carbamoyltransferase 0.74 PFR28_03289 Acetyl-coenzyme A synthetase — —
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_2347 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.73 Pf1N1B4_3430 Acetyl-coenzyme A synthetase (EC 6.2.1.1) — —
Pseudomonas fluorescens FW300-N2E3 0.25 AO353_08135 aspartate carbamoyltransferase catalytic subunit 0.73 AO353_03060 Acetyl-coenzyme A synthetase (EC 6.2.1.1) (from data) — —
Pseudomonas sp. DMC3 0.25 GFF204 Aspartate carbamoyltransferase 0.73 GFF4887 Acetyl-coenzyme A synthetase — —
Pseudomonas fluorescens GW456-L13 0.25 PfGW456L13_1016 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.73 PfGW456L13_1963 Acetyl-coenzyme A synthetase (EC 6.2.1.1) — —
Pseudomonas fluorescens FW300-N2C3 0.25 AO356_13450 aspartate carbamoyltransferase catalytic subunit 0.74 AO356_18695 Acetyl-coenzyme A synthetase (EC 6.2.1.1) (from data) — —
Pseudomonas fluorescens FW300-N2E2 0.25 Pf6N2E2_4606 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.74 Pf6N2E2_5659 Acetyl-coenzyme A synthetase (EC 6.2.1.1) — —
Pseudomonas stutzeri RCH2 0.24 Psest_0291 aspartate carbamoyltransferase 0.69 Psest_2657 acetate--CoA ligase — —
Pseudomonas simiae WCS417 0.24 PS417_26700 aspartate carbamoyltransferase catalytic subunit 0.73 PS417_21750 acetyl-CoA synthetase — —
Lysobacter sp. OAE881 0.24 ABIE51_RS16015 aspartate carbamoyltransferase catalytic subunit 0.64 ABIE51_RS01660 acetate--CoA ligase low > 62
Pseudomonas sp. SVBP6 0.24 COO64_RS13575 aspartate carbamoyltransferase catalytic subunit 0.75 COO64_RS21645 acs acetate--CoA ligase low > 93
Marinobacter adhaerens HP15 0.24 HP15_3507 aspartate carbamoyltransferase 0.71 HP15_811 acetyl-CoA synthetase low > 73
Pseudomonas lactucae CFBP13502 0.24 GEMAOFIL_05477 Aspartate carbamoyltransferase 0.73 GEMAOFIL_04492 Acetyl-coenzyme A synthetase — —
Cellulophaga baltica 18 0.24 M666_RS11460 aspartate carbamoyltransferase catalytic subunit 0.51 M666_RS12955 acetate--CoA ligase low > 67
Pseudomonas fluorescens SBW25 0.24 PFLU_RS28345 aspartate carbamoyltransferase 0.73 PFLU_RS23355 acetate--CoA ligase — —
Pedobacter sp. GW460-11-11-14-LB5 0.24 CA265_RS14660 aspartate carbamoyltransferase 0.55 CA265_RS16340 acetate--CoA ligase — —
Pseudomonas fluorescens SBW25-INTG 0.24 PFLU_RS28345 aspartate carbamoyltransferase 0.73 PFLU_RS23355 acetate--CoA ligase — —
Pseudomonas putida KT2440 0.24 PP_4998 Aspartate carbamoyltransferase 0.75 PP_4487 acetyl-CoA synthetase — —
Pseudomonas sp. BP01 0.24 JOY50_RS09700 aspartate carbamoyltransferase catalytic subunit 0.75 JOY50_RS01010 acs acetate--CoA ligase low > 84
Dyella japonica UNC79MFTsu3.2 0.24 ABZR86_RS10390 aspartate carbamoyltransferase catalytic subunit 0.67 ABZR86_RS15200 acetate--CoA ligase — —
Rhodanobacter denitrificans MT42 0.23 LRK55_RS03990 aspartate carbamoyltransferase catalytic subunit 0.66 LRK55_RS08185 acetate--CoA ligase — —
Pseudomonas syringae pv. syringae B728a 0.23 Psyr_0482 aspartate carbamoyltransferase 0.73 Psyr_3572 acetyl-coenzyme A synthetase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.23 Psyr_0482 aspartate carbamoyltransferase 0.73 Psyr_3572 acetyl-coenzyme A synthetase — —
Rhodanobacter denitrificans FW104-10B01 0.23 LRK54_RS04220 aspartate carbamoyltransferase catalytic subunit 0.66 LRK54_RS08420 acetate--CoA ligase — —
Acinetobacter radioresistens SK82 0.23 MPMX26_01099 Aspartate carbamoyltransferase 0.66 MPMX26_02906 Acetyl-coenzyme A synthetase low > 36
Mucilaginibacter yixingensis YX-36 DSM 26809 0.23 ABZR88_RS03460 aspartate carbamoyltransferase catalytic subunit 0.52 ABZR88_RS15400 acetate--CoA ligase — —
Magnetospirillum magneticum AMB-1 0.23 AMB_RS18300 aspartate carbamoyltransferase 0.69 AMB_RS21140 acetate--CoA ligase — —
Cupriavidus basilensis FW507-4G11 0.23 RR42_RS15860 aspartate carbamoyltransferase catalytic subunit 0.49 RR42_RS13880 AMP-dependent synthetase — —
Dinoroseobacter shibae DFL-12 0.23 Dshi_3091 aspartate carbamoyltransferase (RefSeq) 0.64 Dshi_3553 acetate--CoA ligase (RefSeq) — —
Pseudomonas sp. S08-1 0.23 OH686_10940 aspartate carbamoyltransferase 0.75 OH686_21250 acetate--CoA ligase — —
Rhodanobacter sp000427505 FW510-R12 0.23 LRK53_RS05705 aspartate carbamoyltransferase catalytic subunit 0.66 LRK53_RS00080 acetate--CoA ligase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.23 Echvi_4661 aspartate carbamoyltransferase 0.53 Echvi_1268 acetate--CoA ligase — —
Pseudomonas aeruginosa PA14 0.23 IKLFDK_23410 aspartate carbamoyltransferase catalytic subunit 0.73 IKLFDK_03940 acetate--CoA ligase low > 100
Pseudomonas segetis P6 0.23 MPMX49_00620 Aspartate carbamoyltransferase 0.74 MPMX49_01868 Acetyl-coenzyme A synthetase — —
Methylophilus sp. DMC18 0.23 GFF868 Aspartate carbamoyltransferase 0.47 GFF994 Acetyl-coenzyme A synthetase — —
Acinetobacter baumannii LAC-4 0.23 RR41_RS10085 aspartate carbamoyltransferase catalytic subunit 0.67 RR41_RS00965 acetate--CoA ligase — —
Dechlorosoma suillum PS 0.23 Dsui_0596 aspartate carbamoyltransferase 0.48 Dsui_2003 acetate--CoA ligase — —
Ralstonia solanacearum IBSBF1503 0.22 RALBFv3_RS12625 aspartate carbamoyltransferase catalytic subunit 0.47 RALBFv3_RS02445 acetate--CoA ligase — —
Ralstonia sp. UNC404CL21Col 0.22 ABZR87_RS08625 aspartate carbamoyltransferase catalytic subunit 0.48 ABZR87_RS14360 acetate--CoA ligase low > 80
Ralstonia solanacearum UW163 0.22 UW163_RS00940 aspartate carbamoyltransferase catalytic subunit 0.47 UW163_RS11280 acetate--CoA ligase — —
Phaeobacter inhibens DSM 17395 0.22 PGA1_c03060 aspartate carbamoyltransferase PyrB 0.61 PGA1_c12950 acetyl-coenzyme A synthetase Acs low > 62
Ralstonia solanacearum PSI07 0.22 RPSI07_RS20635 aspartate carbamoyltransferase catalytic subunit 0.47 RPSI07_RS14880 acetate--CoA ligase — —
Ralstonia solanacearum GMI1000 0.22 RS_RS03410 aspartate carbamoyltransferase 0.47 RS_RS09815 acetyl-coenzyme A synthetase — —
Azospirillum brasilense Sp245 0.22 AZOBR_RS20575 aspartate carbamoyltransferase 0.70 AZOBR_RS00270 acetyl-CoA synthetase low > 97
Rhodanobacter sp. FW510-T8 0.22 OKGIIK_11095 pyrB aspartate carbamoyltransferase catalytic subunit 0.64 OKGIIK_15190 acs acetate--CoA ligase — —
Herbaspirillum seropedicae SmR1 0.22 HSERO_RS02330 aspartate carbamoyltransferase 0.47 HSERO_RS07770 acetyl-CoA synthetase low > 78
Rhodospirillum rubrum S1H 0.22 Rru_A3190 Aspartate carbamoyltransferase (NCBI) 0.69 Rru_A3575 Acetate--CoA ligase (NCBI) low > 58
Azospirillum sp. SherDot2 0.22 MPMX19_01054 Aspartate carbamoyltransferase 0.69 MPMX19_02038 Acetyl-coenzyme A synthetase low > 112
Synechococcus elongatus PCC 7942 0.21 Synpcc7942_0670 pyrB aspartate carbamoyltransferase catalytic subunit 0.52 Synpcc7942_1352 acsA acetyl-CoA synthetase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.21 GFF651 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.48 GFF4107 Acetyl-coenzyme A synthetase (EC 6.2.1.1) low > 90
Sphingobium sp. HT1-2 0.21 GFF1872 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.65 GFF4891 Acetyl-CoA synthetase (EC 6.2.1.1) — —
Mycobacterium tuberculosis H37Rv 0.21 Rv1380 Probable aspartate carbamoyltransferase PyrB (ATCase) (aspartate transcarbamylase) 0.45 Rv3667 Acetyl-coenzyme A synthetase Acs (acetate--CoA ligase) (acetyl-CoA synthetase) (acetyl-CoA synthase) (acyl-activating enzyme) (acetate thiokinase) (acetyl-activating enzyme) (acetate--coenzyme A ligase) (acetyl-coenzyme A synthase) — —
Acidovorax sp. GW101-3H11 0.21 Ac3H11_3978 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.47 Ac3H11_951 Acetyl-coenzyme A synthetase (EC 6.2.1.1) — —
Synechocystis sp000284455 PCC 6803 0.21 SGL_RS10555 aspartate carbamoyltransferase 0.51 SGL_RS15030 acetate--CoA ligase — —
Sinorhizobium meliloti 1021 0.21 SMc01360 aspartate carbamoyltransferase catalytic subunit 0.68 SMc04093 acetyl-CoA synthetase low > 103
Bosea sp. OAE506 0.20 ABIE41_RS17230 aspartate carbamoyltransferase catalytic subunit 0.68 ABIE41_RS05675 acetate--CoA ligase low > 77
Desulfovibrio vulgaris Hildenborough JW710 0.20 DVU2901 pyrB aspartate carbamoyltransferase (TIGR) 0.54 DVU2969 acetoacetyl-CoA synthase (TIGR) — —
Agrobacterium fabrum C58 0.20 Atu1308 aspartate carbamoyl transferase catalytic subunit 0.68 Atu2745 acetyl-coenzyme A synthetase low > 89
Xanthobacter sp. DMC5 0.19 GFF929 Aspartate carbamoyltransferase 0.69 GFF160 Acetyl-coenzyme A synthetase — —
Rhodopseudomonas palustris CGA009 0.19 TX73_016120 aspartate carbamoyltransferase catalytic subunit 0.68 TX73_001095 acetate--CoA ligase — —
Desulfovibrio vulgaris Miyazaki F 0.19 DvMF_1425 pyrB aspartate carbamoyltransferase catalytic subunit (RefSeq) 0.54 DvMF_1775 acetate/CoA ligase (RefSeq) low > 51

Not shown: 5 genomes with orthologs for CSW01_12725 only; 12 genomes with orthologs for CSW01_01520 only