Homologs of GFF3906 from Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)
SEED: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)
KEGG: phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase

Top 100 hits from BLASTp (E < 0.01)

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Orth Species Gene Name Description Fitness %Id Cov
  Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 GFF3906 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) insig. 100 100
o Escherichia coli BL21 ECD_01928 phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase insig. 92 100
o Escherichia coli BW25113 b2026 hisI bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) strong 92 100
o Escherichia coli ECRC62 BNILDI_14710 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE strong 92 100
o Escherichia coli ECOR38 HEPCGN_03190 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE strong 92 100
o Escherichia coli HS(pFamp)R (ATCC 700891) OHPLBJKB_01674 Histidine biosynthesis bifunctional protein HisIE insig. 91 100
o Enterobacter sp. TBS_079 MPMX20_03008 Histidine biosynthesis bifunctional protein HisIE strong 89 100
o Enterobacter asburiae PDN3 EX28DRAFT_0533 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)/phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) strong 88 100
o Escherichia coli ECRC100 OKFHMN_24485 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE strong 93 100
o Escherichia coli ECRC101 MCAODC_20455 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE strong 93 100
o Escherichia coli ECRC102 NIAGMN_22430 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE no data 93 100
o Escherichia coli ECRC98 JDDGAC_28595 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE cofit 93 100
o Escherichia coli ECRC99 KEDOAH_03665 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE no data 93 100
o Escherichia coli Nissle 1917 ECOLIN_RS11975 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE no data 92 100
o Escherichia coli ECOR27 NOLOHH_15800 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE cofit 92 100
o Escherichia fergusonii Becca EFB2_01830 Histidine biosynthesis bifunctional protein HisIE insig. 91 100
o Klebsiella michiganensis M5al BWI76_RS18955 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase strong 83 100
o Pantoea sp. MT58 IAI47_07060 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE strong 79 100
o Dickeya dadantii 3937 DDA3937_RS09705 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE strong 80 100
o Dickeya dianthicola ME23 DZA65_RS10025 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE strong 79 100
o Dickeya dianthicola 67-19 HGI48_RS09715 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE insig. 79 100
o Erwinia tracheiphila SCR3 LU632_RS08915 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE strong 82 100
o Erwinia amylovora T8 OLJFJH_12150 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE strong 78 100
o Rahnella sp. WP5 EX31_RS11470 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE strong 80 100
o Serratia liquefaciens MT49 IAI46_08180 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE strong 81 100
o Pectobacterium carotovorum WPP14 HER17_RS12260 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE strong 79 91
o Vibrio cholerae E7946 ATCC 55056 CSW01_05780 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase insig. 68 96
o Alteromonas macleodii MIT1002 MIT1002_02639 Phosphoribosyl-ATP pyrophosphatase strong 63 100
o Shewanella oneidensis MR-1 SO2067 hisI phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolase (NCBI ptt file) strong 63 99
o Shewanella amazonensis SB2B Sama_1948 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) strong 61 100
o Shewanella sp. ANA-3 Shewana3_1847 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) cofit 63 96
o Rhodanobacter denitrificans MT42 LRK55_RS01355 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE cofit 61 95
o Shewanella loihica PV-4 Shew_2204 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) cofit 60 95
o Rhodanobacter sp. FW510-T8 OKGIIK_04980 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE cofit 61 95
o Rhodanobacter sp000427505 FW510-R12 LRK53_RS08490 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE cofit 60 95
o Dyella japonica UNC79MFTsu3.2 ABZR86_RS06700 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE strong 58 96
o Rhodanobacter denitrificans FW104-10B01 LRK54_RS01575 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE strong 59 96
o Xanthomonas campestris pv. campestris strain 8004 Xcc-8004.2942.1 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) strong 59 96
o Mucilaginibacter yixingensis YX-36 DSM 26809 ABZR88_RS06845 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE no data 53 96
o Echinicola vietnamensis KMM 6221, DSM 17526 Echvi_2517 phosphoribosyl-ATP pyrophosphohydrolase strong 52 96
o Bacteroides thetaiotaomicron VPI-5482 BT1377 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase (NCBI ptt file) strong 51 96
o Bacteroides ovatus ATCC 8483 BACOVA_00218 phosphoribosyl-ATP diphosphatase strong 51 96
o Pedobacter sp. GW460-11-11-14-LB5 CA265_RS03605 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase strong 52 96
o Cellulophaga baltica 18 M666_RS17125 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE insig. 50 96
o Bacteroides stercoris CC31F HMPREF1181_RS11065 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE strong 51 95
o Parabacteroides merdae CL09T00C40 HMPREF1078_RS13560 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE strong 49 96
o Lysobacter sp. OAE881 ABIE51_RS13295 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE strong 59 95
o Phocaeicola vulgatus CL09T03C04 HMPREF1058_RS06180 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE strong 49 96
o Phocaeicola dorei CL03T12C01 ABI39_RS19935 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE strong 49 96
o Brevundimonas sp. GW460-12-10-14-LB2 A4249_RS10720 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE strong 52 96
o Pontibacter actiniarum KMM 6156, DSM 19842 CA264_05115 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase insig. 54 96
o Synechococcus elongatus PCC 7942 Synpcc7942_1995 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein no data 39 92
o Acinetobacter radioresistens SK82 MPMX26_00264 Histidine biosynthesis bifunctional protein HisIE strong 36 91
o Synechocystis sp000284455 PCC 6803 SGL_RS18375 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE no data 39 92
  Dinoroseobacter shibae DFL-12 Dshi_1515 Phosphoribosyl-AMP cyclohydrolase (RefSeq) no data 51 44
  Phaeobacter inhibens DSM 17395 PGA1_c14400 phosphoribosyl-AMP cyclohydrolase Hisl no data 52 44
  Bifidobacterium breve UCC2003 BBR_RS16090 phosphoribosyl-AMP cyclohydrolase strong 53 44
  Pseudomonas fluorescens SBW25 PFLU_RS29990 phosphoribosyl-AMP cyclohydrolase sig. 47 52
  Pseudomonas fluorescens SBW25-INTG PFLU_RS29990 phosphoribosyl-AMP cyclohydrolase strong 47 52
  Sphingomonas koreensis DSMZ 15582 Ga0059261_3630 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) strong 51 44
  Desulfovibrio vulgaris Miyazaki F DvMF_1964 hisI phosphoribosyl-AMP cyclohydrolase (RefSeq) strong 48 47
  Pseudomonas simiae WCS417 PS417_28325 phosphoribosyl-AMP cyclohydrolase insig. 47 49
  Hydrogenophaga sp. GW460-11-11-14-LB1 GFF1307 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) no data 49 48
  Desulfovibrio vulgaris Hildenborough JW710 DVU0113 hisI phosphoribosyl-AMP cyclohydrolase (TIGR) strong 47 47
  Rhodospirillum rubrum S1H Rru_A1612 Phosphoribosyl-AMP cyclohydrolase (NCBI) no data 48 44
  Paraburkholderia sabiae LMG 24235 QEN71_RS27830 phosphoribosyl-AMP cyclohydrolase strong 48 48
  Paraburkholderia bryophila 376MFSha3.1 H281DRAFT_05660 phosphoribosyl-AMP cyclohydrolase no data 50 45
  Paraburkholderia graminis OAS925 ABIE53_003694 phosphoribosyl-AMP cyclohydrolase no data 49 45
  Burkholderia phytofirmans PsJN BPHYT_RS17675 phosphoribosyl-AMP cyclohydrolase cofit 49 45
  Ralstonia solanacearum GMI1000 RS_RS14755 phosphoribosyl-AMP cyclohydrolase no data 49 44
  Ralstonia sp. UNC404CL21Col ABZR87_RS02465 phosphoribosyl-AMP cyclohydrolase no data 48 44
  Variovorax sp. SCN45 GFF5358 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) no data 47 48
  Ralstonia solanacearum IBSBF1503 RALBFv3_RS06810 phosphoribosyl-AMP cyclohydrolase no data 48 44
  Ralstonia solanacearum UW163 UW163_RS06805 phosphoribosyl-AMP cyclohydrolase no data 48 44
  Variovorax sp. OAS795 ABID97_RS23100 phosphoribosyl-AMP cyclohydrolase no data 45 51
  Castellaniella sp019104865 MT123 ABCV34_RS11255 phosphoribosyl-AMP cyclohydrolase cofit 48 44
  Ralstonia solanacearum PSI07 RPSI07_RS10425 phosphoribosyl-AMP cyclohydrolase no data 47 44
  Azospirillum sp. SherDot2 MPMX19_01340 Phosphoribosyl-AMP cyclohydrolase no data 48 44
  Acidovorax sp. GW101-3H11 Ac3H11_4735 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) no data 47 48
  Mycobacterium tuberculosis H37Rv Rv1606 Probable phosphoribosyl-AMP 1,6 cyclohydrolase HisI no data 46 44
  Cupriavidus basilensis FW507-4G11 RR42_RS18880 phosphoribosyl-AMP cyclohydrolase no data 43 60
  Kangiella aquimarina DSM 16071 B158DRAFT_2292 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (EC 5.3.1.16)/phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)/phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) insig. 32 95
  Caulobacter crescentus NA1000 CCNA_00489 phosphoribosyl-AMP cyclohydrolase strong 46 45
  Caulobacter crescentus NA1000 Δfur CCNA_00489 phosphoribosyl-AMP cyclohydrolase cofit 46 45
  Marinobacter adhaerens HP15 HP15_3194 phosphoribosyl-AMP cyclohydrolase strong 46 44
  Azospirillum brasilense Sp245 AZOBR_RS08645 phosphoribosyl-AMP cyclohydrolase no data 46 44
  Rhodopseudomonas palustris CGA009 TX73_017530 phosphoribosyl-AMP cyclohydrolase no data 43 44
  Magnetospirillum magneticum AMB-1 AMB_RS11660 phosphoribosyl-AMP cyclohydrolase no data 43 47
  Pseudomonas stutzeri RCH2 Psest_3943 Phosphoribosyl-AMP cyclohydrolase strong 42 48
  Pseudomonas sp. SVBP6 COO64_RS13500 hisI phosphoribosyl-AMP cyclohydrolase strong 36 66
  Methylophilus sp. DMC18 GFF1569 Phosphoribosyl-AMP cyclohydrolase no data 44 44
  Pseudomonas sp. DMC3 GFF3073 Phosphoribosyl-AMP cyclohydrolase cofit 35 66
  Pseudomonas fluorescens FW300-N1B4 Pf1N1B4_1565 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) strong 35 66
  Herbaspirillum seropedicae SmR1 HSERO_RS20310 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) (from data) strong 43 48
  Pseudomonas fluorescens FW300-N2E3 AO353_12365 phosphoribosyl-AMP cyclohydrolase strong 41 48
  Pseudomonas fluorescens GW456-L13 PfGW456L13_302 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) strong 34 67
  Pseudomonas fluorescens FW300-N2C3 AO356_09520 phosphoribosyl-AMP cyclohydrolase strong 42 48
  Pseudomonas fluorescens FW300-N2E2 Pf6N2E2_3782 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) strong 42 48
  Dinoroseobacter shibae DFL-12 Dshi_2575 phosphoribosyl-ATP pyrophosphohydrolase (RefSeq) no data 48 44
  Pseudomonas simiae WCS417 PS417_01855 phosphoribosyl-AMP cyclohydrolase strong 35 66