| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_08595 | | insulinase family protein | insig. | 100 | 100 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_09885 | | hypothetical protein | strong | 25 | 77 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_11470 | | peptidase M16 | insig. | 23 | 87 |
| o | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS18840 | | pitrilysin family protein | cofit | 25 | 85 |
| o | Kangiella aquimarina DSM 16071 | B158DRAFT_0838 | | Predicted Zn-dependent peptidases | insig. | 25 | 90 |
| o | Bacteroides stercoris CC31F | HMPREF1181_RS05980 | | insulinase family protein | insig. | 22 | 97 |
| o | Caulobacter crescentus NA1000 | CCNA_02721 | | peptidase, M16 family | no data | 24 | 97 |
| o | Caulobacter crescentus NA1000 Δfur | CCNA_02721 | | peptidase, M16 family | no data | 24 | 97 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS06730 | | insulinase family protein | insig. | 24 | 78 |
| o | Bacteroides thetaiotaomicron VPI-5482 | BT4320 | | putative zinc protease (NCBI ptt file) | sig. | 22 | 100 |
| o | Bacteroides ovatus ATCC 8483 | BACOVA_05120 | | peptidase M16 inactive domain protein | strong | 22 | 100 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS18245 | | insulinase family protein | insig. | 23 | 77 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS05860 | | insulinase family protein | sig. | 22 | 74 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS02280 | | insulinase family protein | cofit | 24 | 82 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_02223 | | hypothetical protein | cofit | 39 | 22 |
| | Escherichia coli BL21 | ECD_01452 | | putative periplasmic M16 family zinc metalloendopeptidase | insig. | 39 | 22 |
| | Escherichia coli ECOR27 | NOLOHH_18920 | pqqL | putative zinc protease PqqL | insig. | 39 | 22 |
| | Escherichia coli ECOR38 | HEPCGN_26520 | pqqL | putative zinc protease PqqL | insig. | 39 | 22 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS08575 | | M16 family metallopeptidase | insig. | 39 | 22 |
| | Escherichia coli BW25113 | b1494 | pqqL | predicted peptidase (NCBI) | insig. | 39 | 22 |
| | Escherichia coli ECRC62 | BNILDI_17410 | pqqL | putative zinc protease PqqL | insig. | 39 | 22 |
| | Escherichia coli ECRC100 | OKFHMN_01280 | pqqL | putative zinc protease PqqL | cofit | 39 | 22 |
| | Escherichia coli ECRC101 | MCAODC_16660 | pqqL | putative zinc protease PqqL | insig. | 39 | 22 |
| | Escherichia coli ECRC102 | NIAGMN_25410 | pqqL | putative zinc protease PqqL | cofit | 39 | 22 |
| | Escherichia coli ECRC98 | JDDGAC_03770 | pqqL | putative zinc protease PqqL | insig. | 39 | 22 |
| | Escherichia coli ECRC99 | KEDOAH_27160 | pqqL | putative zinc protease PqqL | no data | 39 | 22 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU2379 | pqqL | peptidase, M16 family, putative (TIGR) | insig. | 37 | 26 |
| o | Shewanella oneidensis MR-1 | SO4022 | | peptidase, M16 family (NCBI ptt file) | insig. | 24 | 86 |
| o | Shewanella sp. ANA-3 | Shewana3_3588 | | peptidase M16 domain-containing protein (RefSeq) | cofit | 23 | 83 |
| o | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1465 | | Predicted Zn-dependent peptidases | strong | 22 | 88 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_07495 | | Insulinase (Peptidase family M16) | sig. | 25 | 48 |
| | Sphingobium sp. HT1-2 | GFF3946 | | Peptidase, M16 family | cofit | 33 | 23 |
| o | Pectobacterium carotovorum WPP14 | HER17_RS17245 | | insulinase family protein | insig. | 22 | 97 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_4050 | | Predicted Zn-dependent peptidases | cofit | 25 | 48 |
| | Enterobacter sp. TBS_079 | MPMX20_04412 | | Protein YhjJ | sig. | 25 | 48 |
| | Klebsiella michiganensis M5al | BWI76_RS26755 | | peptidase M16 | strong | 24 | 48 |
| | Serratia liquefaciens MT49 | IAI46_00555 | | insulinase family protein | cofit | 25 | 49 |
| o | Dickeya dadantii 3937 | DDA3937_RS04385 | | insulinase family protein | insig. | 34 | 21 |
| | Dickeya dianthicola 67-19 | HGI48_RS20830 | | insulinase family protein | insig. | 24 | 50 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_0236 | | peptidase M16 domain protein (RefSeq) | strong | 35 | 25 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU1430 | | peptidase, M16 family (TIGR) | sig. | 32 | 29 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_16675 | | peptidase M16 | insig. | 31 | 26 |
| | Dickeya dadantii 3937 | DDA3937_RS00560 | | insulinase family protein | cofit | 24 | 50 |
| | Escherichia coli ECOR27 | NOLOHH_08165 | pqqL | Insulinase (Peptidase family M16) | insig. | 23 | 48 |
| | Escherichia coli ECOR38 | HEPCGN_15105 | yhjJ | Protein YhjJ | insig. | 23 | 48 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS15570 | | insulinase family protein | cofit | 25 | 48 |
| | Dickeya dianthicola ME23 | DZA65_RS21845 | | insulinase family protein | insig. | 24 | 50 |
| | Escherichia fergusonii Becca | EFB2_00281 | | Protein YhjJ | insig. | 24 | 48 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS20175 | | pitrilysin family protein | insig. | 24 | 48 |
| | Escherichia coli BL21 | ECD_03375 | | putative periplasmic M16 family chaperone | sig. | 23 | 48 |
| | Escherichia coli ECRC100 | OKFHMN_16200 | pqqL | Insulinase (Peptidase family M16) | insig. | 23 | 48 |
| | Escherichia coli ECRC101 | MCAODC_06715 | pqqL | Insulinase (Peptidase family M16) | insig. | 23 | 48 |
| | Escherichia coli ECRC102 | NIAGMN_13965 | pqqL | Insulinase (Peptidase family M16) | cofit | 23 | 48 |
| | Escherichia coli ECRC62 | BNILDI_03390 | pqqL | Insulinase (Peptidase family M16) | cofit | 23 | 48 |
| | Escherichia coli ECRC98 | JDDGAC_19830 | pqqL | Insulinase (Peptidase family M16) | insig. | 23 | 48 |
| | Escherichia coli ECRC99 | KEDOAH_11950 | pqqL | Insulinase (Peptidase family M16) | no data | 23 | 48 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_00175 | | Protein YhjJ | insig. | 23 | 48 |
| | Escherichia coli BW25113 | b3527 | yhjJ | predicted zinc-dependent peptidase (NCBI) | strong | 23 | 48 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF496 | | Protein YhjJ, putative peptidase | insig. | 23 | 45 |
| | Pantoea sp. MT58 | IAI47_18580 | | insulinase family protein | sig. | 25 | 48 |
| | Erwinia amylovora T8 | OLJFJH_04800 | | peptidase M16 | strong | 24 | 48 |
| | Rahnella sp. WP5 | EX31_RS05440 | | insulinase family protein | insig. | 24 | 46 |
| | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_10170 | | peptidase M16 | cofit | 24 | 48 |
| | Erwinia tracheiphila SCR3 | LU632_RS00335 | | insulinase family protein | cofit | 24 | 48 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF815 | | FIG015547: peptidase, M16 family | insig. | 30 | 29 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_02965 | | insulinase family protein | insig. | 26 | 45 |
| | Alteromonas macleodii MIT1002 | MIT1002_01221 | | protease3 | cofit | 31 | 23 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1019 | | Predicted Zn-dependent peptidases | insig. | 31 | 23 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_14305 | | insulinase family protein | insig. | 31 | 27 |
| | Caulobacter crescentus NA1000 | CCNA_02661 | | M16 family peptidase | cofit | 30 | 23 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_02661 | | M16 family peptidase | cofit | 30 | 23 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS07535 | | pitrilysin family protein | cofit | 30 | 28 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS07805 | | insulinase family protein | insig. | 30 | 28 |
| | Shewanella oneidensis MR-1 | SO3560 | | peptidase, M16 family (NCBI ptt file) | strong | 32 | 23 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS00710 | | insulinase family protein | insig. | 30 | 27 |
| | Shewanella sp. ANA-3 | Shewana3_3161 | | peptidase M16 domain-containing protein (RefSeq) | insig. | 29 | 27 |
| | Lysobacter sp. OAE881 | ABIE51_RS00275 | | pitrilysin family protein | insig. | 31 | 22 |
| | Shewanella sp. ANA-3 | Shewana3_0842 | | peptidase M16 domain-containing protein (RefSeq) | insig. | 29 | 25 |
| | Shewanella loihica PV-4 | Shew_0655 | | peptidase M16 domain-containing protein (RefSeq) | insig. | 31 | 24 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_18335 | | peptidase M16 | sig. | 29 | 23 |
| | Pectobacterium carotovorum WPP14 | HER17_RS00405 | | insulinase family protein | cofit | 22 | 52 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS12850 | | pitrilysin family protein | insig. | 28 | 25 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS17980 | | peptidase M16 | insig. | 28 | 27 |
| | Shewanella loihica PV-4 | Shew_1226 | | peptidase M16 domain-containing protein (RefSeq) | strong | 29 | 28 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_1744 | | Predicted Zn-dependent peptidases | insig. | 31 | 26 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS10340 | | pitrilysin family protein | cofit | 25 | 36 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS21440 | | DNA-3-methyladenine glycosylase | insig. | 29 | 23 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_12610 | | hypothetical protein | insig. | 29 | 23 |
| | Shewanella amazonensis SB2B | Sama_3596 | | pseudouridine synthase, Rsu (RefSeq) | sig. | 26 | 38 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_1780 | | Predicted Zn-dependent peptidases | insig. | 28 | 23 |
| | Rhodopseudomonas palustris CGA009 | TX73_022675 | | pitrilysin family protein | cofit | 30 | 23 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS17330 | | pseudouridine synthase | insig. | 29 | 23 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS21180 | | pitrilysin family protein | insig. | 25 | 31 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1432 | | Predicted Zn-dependent peptidases | insig. | 29 | 23 |
| | Caulobacter crescentus NA1000 | CCNA_03699 | | peptidase, M16 family | cofit | 29 | 22 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_03699 | | peptidase, M16 family | cofit | 29 | 22 |
| | Pseudomonas putida KT2440 | PP_5115 | | putative Zinc protease | insig. | 29 | 22 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.813.1 | | Predicted Zn-dependent peptidases | insig. | 28 | 25 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS00205 | | insulinase family protein | cofit | 29 | 22 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_1428 | | Predicted Zn-dependent peptidases | strong | 28 | 23 |