Conservation of cofitness between PP_0363 and PP_4699 in Pseudomonas putida KT2440

97 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_0363 8-amino-7-oxononanoate synthase 1.0 PP_4699 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.49 20
Pseudomonas syringae pv. syringae B728a ΔmexB 0.84 Psyr_4686 8-amino-7-oxononanoate synthase 0.85 Psyr_0828 ketopantoate hydroxymethyltransferase 0.46 40
Pseudomonas syringae pv. syringae B728a 0.84 Psyr_4686 8-amino-7-oxononanoate synthase 0.85 Psyr_0828 ketopantoate hydroxymethyltransferase — —
Pseudomonas fluorescens GW456-L13 0.84 PfGW456L13_1148 8-amino-7-oxononanoate synthase (EC 2.3.1.47) 0.84 PfGW456L13_1521 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) low > 87
Pseudomonas sp. RS175 0.84 PFR28_04102 8-amino-7-oxononanoate synthase 0.82 PFR28_03721 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.34 36
Pseudomonas fluorescens FW300-N2E3 0.83 AO353_07520 8-amino-7-oxononanoate synthase 0.84 AO353_14385 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 101
Pseudomonas fluorescens FW300-N2E2 0.83 Pf6N2E2_4761 8-amino-7-oxononanoate synthase (EC 2.3.1.47) 0.83 Pf6N2E2_5153 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) 0.57 12
Pseudomonas fluorescens FW300-N1B4 0.83 Pf1N1B4_2488 8-amino-7-oxononanoate synthase (EC 2.3.1.47) 0.83 Pf1N1B4_2854 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) 0.46 63
Pseudomonas fluorescens SBW25-INTG 0.82 PFLU_RS27645 8-amino-7-oxononanoate synthase 0.85 PFLU_RS25750 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.51 10
Pseudomonas fluorescens SBW25 0.82 PFLU_RS27645 8-amino-7-oxononanoate synthase 0.85 PFLU_RS25750 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.47 51
Pseudomonas simiae WCS417 0.82 PS417_26000 8-amino-7-oxononanoate synthase 0.86 PS417_23910 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.29 23
Pseudomonas stutzeri RCH2 0.82 Psest_0412 8-amino-7-oxononanoate synthase 0.78 Psest_0996 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Pseudomonas sp. S08-1 0.81 OH686_10350 8-amino-7-oxononanoate synthase 0.82 OH686_17245 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Pseudomonas fluorescens FW300-N2C3 0.81 AO356_14140 8-amino-7-oxononanoate synthase 0.83 AO356_16060 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.32 97
Marinobacter adhaerens HP15 0.56 HP15_2485 8-amino-7-oxononanoate synthase 0.60 HP15_324 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Dechlorosoma suillum PS 0.49 Dsui_2881 8-amino-7-oxononanoate synthase 0.56 Dsui_1471 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Kangiella aquimarina DSM 16071 0.48 B158DRAFT_0865 8-amino-7-oxononanoate synthase 0.56 B158DRAFT_0061 ketopantoate hydroxymethyltransferase (EC 2.1.2.11) — —
Dyella japonica UNC79MFTsu3.2 0.46 ABZR86_RS15835 8-amino-7-oxononanoate synthase 0.46 ABZR86_RS00815 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Rhodanobacter denitrificans MT42 0.46 LRK55_RS09895 8-amino-7-oxononanoate synthase 0.48 LRK55_RS14830 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 63
Rhodanobacter denitrificans FW104-10B01 0.45 LRK54_RS10255 8-amino-7-oxononanoate synthase 0.49 LRK54_RS15115 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Rhodanobacter sp. FW510-T8 0.44 OKGIIK_13655 bioF 8-amino-7-oxononanoate synthase 0.47 OKGIIK_03885 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 52
Lysobacter sp. OAE881 0.42 ABIE51_RS01145 8-amino-7-oxononanoate synthase 0.54 ABIE51_RS08025 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Enterobacter sp. TBS_079 0.42 MPMX20_01404 8-amino-7-oxononanoate synthase 0.59 MPMX20_00827 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 85
Xanthomonas campestris pv. campestris strain 8004 0.41 Xcc-8004.504.1 8-amino-7-oxononanoate synthase (EC 2.3.1.47) 0.52 Xcc-8004.3052.1 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) — —
Enterobacter asburiae PDN3 0.40 EX28DRAFT_2215 8-amino-7-oxononanoate synthase 0.58 EX28DRAFT_3730 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.74 8
Dickeya dianthicola 67-19 0.40 HGI48_RS08680 8-amino-7-oxononanoate synthase 0.58 HGI48_RS16070 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.85 9
Dickeya dianthicola ME23 0.40 DZA65_RS08970 8-amino-7-oxononanoate synthase 0.57 DZA65_RS17155 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 75
Dickeya dadantii 3937 0.40 DDA3937_RS08515 8-amino-7-oxononanoate synthase 0.58 DDA3937_RS15955 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.50 21
Herbaspirillum seropedicae SmR1 0.40 HSERO_RS12245 8-amino-7-oxononanoate synthase 0.58 HSERO_RS03085 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 78
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.38 GFF672 8-amino-7-oxononanoate synthase (EC 2.3.1.47) 0.56 GFF91 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) low > 78
Pectobacterium carotovorum WPP14 0.38 HER17_RS13455 8-amino-7-oxononanoate synthase 0.57 HER17_RS05560 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 75
Vibrio cholerae E7946 ATCC 55056 0.38 CSW01_05650 8-amino-7-oxononanoate synthase 0.56 CSW01_03135 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Erwinia tracheiphila SCR3 0.38 LU632_RS09135 bioF 8-amino-7-oxononanoate synthase 0.56 LU632_RS20100 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Paraburkholderia graminis OAS925 0.37 ABIE53_000579 8-amino-7-oxononanoate synthase 0.57 ABIE53_000867 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Escherichia coli Nissle 1917 0.37 ECOLIN_RS04135 8-amino-7-oxononanoate synthase 0.59 ECOLIN_RS00745 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Escherichia fergusonii Becca 0.37 EFB2_03329 8-amino-7-oxononanoate synthase 0.59 EFB2_03910 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 86
Paraburkholderia bryophila 376MFSha3.1 0.37 H281DRAFT_02095 8-amino-7-oxononanoate synthase 0.57 H281DRAFT_04703 ketopantoate hydroxymethyltransferase — —
Rahnella sp. WP5 0.37 EX31_RS23700 8-amino-7-oxononanoate synthase 0.58 EX31_RS03280 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 89
Escherichia coli ECRC102 0.37 NIAGMN_04440 bioF 8-amino-7-oxononanoate synthase 0.58 NIAGMN_08250 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Escherichia coli ECRC98 0.37 JDDGAC_10030 bioF 8-amino-7-oxononanoate synthase 0.58 JDDGAC_13995 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Escherichia coli ECRC62 0.37 BNILDI_21035 bioF 8-amino-7-oxononanoate synthase 0.59 BNILDI_08925 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Escherichia coli ECRC101 0.37 OKFHMN_06395 bioF 8-amino-7-oxononanoate synthase 0.58 OKFHMN_10400 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Escherichia coli ECRC101 0.37 MCAODC_25610 bioF 8-amino-7-oxononanoate synthase 0.58 MCAODC_00915 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Escherichia coli ECRC99 0.37 KEDOAH_21515 bioF 8-amino-7-oxononanoate synthase 0.58 KEDOAH_17755 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Paraburkholderia sabiae LMG 24235 0.36 QEN71_RS01095 8-amino-7-oxononanoate synthase 0.58 QEN71_RS26480 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Escherichia coli BL21 0.36 ECD_00743 8-amino-7-oxononanoate synthase 0.59 ECD_00133 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 60
Burkholderia phytofirmans PsJN 0.36 BPHYT_RS02160 8-amino-7-oxononanoate synthase 0.56 BPHYT_RS03605 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.36 OHPLBJKB_02937 8-amino-7-oxononanoate synthase 0.59 OHPLBJKB_03527 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.64 61
Hydrogenophaga sp. GW460-11-11-14-LB1 0.36 GFF3995 8-amino-7-oxononanoate synthase (EC 2.3.1.47) 0.50 GFF1218 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) — —
Escherichia coli BW25113 0.36 b0776 bioF 8-amino-7-oxononanoate synthase (NCBI) 0.59 b0134 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase (NCBI) low > 76
Escherichia coli ECOR27 0.36 NOLOHH_22765 bioF 8-amino-7-oxononanoate synthase 0.59 NOLOHH_02745 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 57
Escherichia coli ECOR38 0.36 HEPCGN_01645 bioF 8-amino-7-oxononanoate synthase 0.59 HEPCGN_08375 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 85
Serratia liquefaciens MT49 0.36 IAI46_06530 8-amino-7-oxononanoate synthase 0.59 IAI46_21240 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 86
Alteromonas macleodii MIT1002 0.36 MIT1002_01380 8-amino-7-oxononanoate synthase 0.58 MIT1002_03694 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Acidovorax sp. GW101-3H11 0.36 Ac3H11_3830 8-amino-7-oxononanoate synthase (EC 2.3.1.47) 0.49 Ac3H11_3839 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) low > 79
Ralstonia solanacearum IBSBF1503 0.35 RALBFv3_RS00820 8-amino-7-oxononanoate synthase 0.58 RALBFv3_RS05315 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Ralstonia solanacearum UW163 0.35 UW163_RS14155 8-amino-7-oxononanoate synthase 0.58 UW163_RS08310 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Ralstonia solanacearum GMI1000 0.35 RS_RS07435 8-amino-7-oxononanoate synthase 0.57 RS_RS13180 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Shewanella oneidensis MR-1 0.35 SO2739 bioF 8-amino-7-oxononanoate synthase (NCBI ptt file) 0.61 SO0870 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase (NCBI ptt file) low > 76
Cupriavidus basilensis FW507-4G11 0.35 RR42_RS00930 8-amino-7-oxononanoate synthase 0.47 RR42_RS17250 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Klebsiella michiganensis M5al 0.35 BWI76_RS08765 8-amino-7-oxononanoate synthase 0.57 BWI76_RS04995 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.19 69
Variovorax sp. OAS795 0.35 ABID97_RS16260 8-amino-7-oxononanoate synthase 0.46 ABID97_RS07435 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 91
Ralstonia solanacearum PSI07 0.35 RPSI07_RS16700 8-amino-7-oxononanoate synthase 0.57 RPSI07_RS11985 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS12340 8-amino-7-oxononanoate synthase 0.53 ABZR87_RS00950 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Shewanella loihica PV-4 0.35 Shew_1720 8-amino-7-oxononanoate synthase (RefSeq) 0.59 Shew_3133 3-methyl-2-oxobutanoate hydroxymethyltransferase (RefSeq) — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.34 CA264_07040 8-amino-7-oxononanoate synthase 0.40 CA264_20605 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Shewanella sp. ANA-3 0.34 Shewana3_2518 aminotransferase, class I and II (RefSeq) 0.60 Shewana3_3408 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase (RefSeq) — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.34 ABZR88_RS03035 pyridoxal phosphate-dependent aminotransferase family protein 0.40 ABZR88_RS17835 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Pedobacter sp. GW460-11-11-14-LB5 0.34 CA265_RS13580 8-amino-7-oxononanoate synthase 0.39 CA265_RS15235 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Pantoea sp. MT58 0.33 IAI47_13525 8-amino-7-oxononanoate synthase 0.55 IAI47_15655 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 76
Phocaeicola dorei CL03T12C01 0.33 ABI39_RS16535 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme 0.37 ABI39_RS14025 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Phocaeicola vulgatus CL09T03C04 0.33 HMPREF1058_RS01195 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme 0.37 HMPREF1058_RS17810 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Variovorax sp. SCN45 0.32 GFF144 8-amino-7-oxononanoate synthase (EC 2.3.1.47) 0.47 GFF2579 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) low > 127
Sinorhizobium meliloti 1021 0.32 SMc01565 2-amino-3-ketobutyrate CoA ligase 0.36 SMc01881 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 103
Rhizobium sp. OAE497 0.32 ABIE40_RS12730 glycine C-acetyltransferase 0.32 ABIE40_RS09465 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 107
Shewanella amazonensis SB2B 0.32 Sama_0098 2-amino-3-ketobutyrate coenzyme A ligase (RefSeq) 0.58 Sama_0776 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase (RefSeq) — —
Parabacteroides merdae CL09T00C40 0.32 HMPREF1078_RS16170 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme 0.34 HMPREF1078_RS09715 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Castellaniella sp019104865 MT123 0.31 ABCV34_RS15295 8-amino-7-oxononanoate synthase 0.36 ABCV34_RS13815 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 48
Bacteroides stercoris CC31F 0.30 HMPREF1181_RS14215 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme 0.36 HMPREF1181_RS16225 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.30 Echvi_0145 2-amino-3-ketobutyrate coenzyme A ligase 0.38 Echvi_1836 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Synechococcus elongatus PCC 7942 0.30 Synpcc7942_0027 bioF 8-amino-7-oxononanoate synthase 0.34 Synpcc7942_2381 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Azospirillum brasilense Sp245 0.30 AZOBR_RS31105 8-amino-7-oxononanoate synthase 0.39 AZOBR_RS06445 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 97
Phaeobacter inhibens DSM 17395 0.30 PGA1_c34330 2-amino-3-ketobutyrate coenzyme A ligase (EC 2.3.1.29) (from data) 0.38 PGA1_c32050 3-methyl-2-oxobutanoate hydroxymethyltransferase PanB — —
Bacteroides ovatus ATCC 8483 0.29 BACOVA_02588 putative 8-amino-7-oxononanoate synthase 0.32 BACOVA_02402 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Bacteroides thetaiotaomicron VPI-5482 0.29 BT1371 2-amino-3-ketobutyrate coenzyme A ligase (NCBI ptt file) 0.32 BT0698 3-methyl-2-oxobutanoate hydroxymethyltransferase (NCBI ptt file) — —
Caulobacter crescentus NA1000 Δfur 0.28 CCNA_01647 8-amino-7-oxononanoate synthase 0.32 CCNA_01723 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Caulobacter crescentus NA1000 0.28 CCNA_01647 8-amino-7-oxononanoate synthase 0.32 CCNA_01723 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Magnetospirillum magneticum AMB-1 0.28 AMB_RS13875 8-amino-7-oxononanoate synthase 0.37 AMB_RS22110 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.28 A4249_RS02505 glycine C-acetyltransferase 0.32 A4249_RS03695 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Rhodopseudomonas palustris CGA009 0.28 TX73_007985 5-aminolevulinate synthase 0.37 TX73_016025 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Sphingomonas koreensis DSMZ 15582 0.27 Ga0059261_3508 7-keto-8-aminopelargonate synthetase and related enzymes 0.37 Ga0059261_0311 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Dinoroseobacter shibae DFL-12 0.27 Dshi_3546 5-aminolevulinic acid synthase (RefSeq) 0.33 Dshi_2966 3-methyl-2-oxobutanoate hydroxymethyltransferase (RefSeq) — —
Azospirillum sp. SherDot2 0.27 MPMX19_02203 5-aminolevulinate synthase 0.37 MPMX19_01580 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Rhodospirillum rubrum S1H 0.26 Rru_A1146 5-aminolevulinic acid synthase (NCBI) 0.31 Rru_A3321 3-methyl-2-oxobutanoate hydroxymethyltransferase (NCBI) — —
Acinetobacter radioresistens SK82 0.26 MPMX26_02453 8-amino-7-oxononanoate synthase 2 0.57 MPMX26_00545 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 36
Agrobacterium fabrum C58 0.25 Atu2613 5-aminolevulinate synthase 0.33 Atu3483 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Desulfovibrio vulgaris Hildenborough JW710 0.20 DVU2564 bioF 8-amino-7-oxononanoate synthase (Dmitry Rodionov) 0.40 DVU2446 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase (TIGR) low > 55
Desulfovibrio vulgaris Miyazaki F 0.18 DvMF_1008 aminotransferase class I and II (RefSeq) 0.41 DvMF_2949 3-methyl-2-oxobutanoate hydroxymethyltransferase (RefSeq) low > 51

Not shown: 4 genomes with orthologs for PP_0363 only; 1 genomes with orthologs for PP_4699 only