Conservation of cofitness between HEPCGN_20570 and HEPCGN_20975 in Escherichia coli ECOR38

97 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR38 1.0 HEPCGN_20570 pdxJ pyridoxine 5'-phosphate synthase 1.0 HEPCGN_20975 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.90 3
Escherichia coli ECRC62 1.00 BNILDI_11900 pdxJ pyridoxine 5'-phosphate synthase 1.00 BNILDI_12270 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.88 9
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01143 'Pyridoxine 5'-phosphate synthase' transl_table=11 1.00 OHPLBJKB_01227 Phosphoribosylformylglycinamidine cyclo-ligase low > 73
Escherichia coli ECRC100 1.00 OKFHMN_21425 pdxJ pyridoxine 5'-phosphate synthase 1.00 OKFHMN_21810 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.76 17
Escherichia coli ECRC101 1.00 MCAODC_11955 pdxJ pyridoxine 5'-phosphate synthase 1.00 MCAODC_12340 purM Phosphoribosylformylglycinamidine cyclo-ligase low > 87
Escherichia coli BL21 1.00 ECD_02458 pyridoxine 5'-phosphate synthase 1.00 ECD_02391 phosphoribosylaminoimidazole synthetase — —
Escherichia coli ECRC102 1.00 NIAGMN_19195 pdxJ pyridoxine 5'-phosphate synthase 1.00 NIAGMN_19580 purM Phosphoribosylformylglycinamidine cyclo-ligase — —
Escherichia coli ECOR27 1.00 NOLOHH_13100 pdxJ pyridoxine 5'-phosphate synthase 1.00 NOLOHH_13460 purM Phosphoribosylformylglycinamidine cyclo-ligase low > 75
Escherichia coli BW25113 1.00 b2564 pdxJ pyridoxal phosphate biosynthetic protein (NCBI) 1.00 b2499 purM phosphoribosylaminoimidazole synthetase (NCBI) 0.53 45
Escherichia coli ECRC98 1.00 JDDGAC_25090 pdxJ pyridoxine 5'-phosphate synthase 1.00 JDDGAC_25755 purM Phosphoribosylformylglycinamidine cyclo-ligase — —
Escherichia coli ECRC99 0.99 KEDOAH_06795 pdxJ pyridoxine 5'-phosphate synthase 1.00 KEDOAH_06410 purM Phosphoribosylformylglycinamidine cyclo-ligase — —
Escherichia fergusonii Becca 0.99 EFB2_01332 Pyridoxine 5'-phosphate synthase 1.00 EFB2_01399 Phosphoribosylformylglycinamidine cyclo-ligase low > 86
Escherichia coli Nissle 1917 0.98 ECOLIN_RS14515 pyridoxine 5'-phosphate synthase 1.00 ECOLIN_RS14190 phosphoribosylformylglycinamidine cyclo-ligase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF2472 'Pyridoxine 5'-phosphate synthase (EC 2.6.99.2)' transl_table=11 0.94 GFF2169 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) — —
Klebsiella michiganensis M5al 0.93 BWI76_RS21305 pyridoxine 5'-phosphate synthase 0.93 BWI76_RS20965 phosphoribosylformylglycinamidine cyclo-ligase — —
Enterobacter sp. TBS_079 0.93 MPMX20_03435 Pyridoxine 5'-phosphate synthase 0.94 MPMX20_03354 Phosphoribosylformylglycinamidine cyclo-ligase low > 85
Enterobacter asburiae PDN3 0.92 EX28DRAFT_0082 pyridoxine 5'-phosphate synthase 0.94 EX28DRAFT_0168 phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) — —
Pectobacterium carotovorum WPP14 0.81 HER17_RS05830 pyridoxine 5'-phosphate synthase 0.89 HER17_RS15465 phosphoribosylformylglycinamidine cyclo-ligase 0.85 46
Dickeya dianthicola 67-19 0.81 HGI48_RS15805 pyridoxine 5'-phosphate synthase 0.86 HGI48_RS06070 phosphoribosylformylglycinamidine cyclo-ligase low > 71
Dickeya dianthicola ME23 0.81 DZA65_RS16885 pyridoxine 5'-phosphate synthase 0.86 DZA65_RS06420 phosphoribosylformylglycinamidine cyclo-ligase low > 75
Dickeya dadantii 3937 0.81 DDA3937_RS15720 pyridoxine 5'-phosphate synthase 0.87 DDA3937_RS06025 phosphoribosylformylglycinamidine cyclo-ligase low > 74
Pantoea sp. MT58 0.79 IAI47_04895 pyridoxine 5'-phosphate synthase 0.89 IAI47_05180 phosphoribosylformylglycinamidine cyclo-ligase 0.65 67
Rahnella sp. WP5 0.79 EX31_RS21850 pyridoxine 5'-phosphate synthase 0.90 EX31_RS22695 phosphoribosylformylglycinamidine cyclo-ligase 0.72 37
Serratia liquefaciens MT49 0.78 IAI46_19535 pyridoxine 5'-phosphate synthase 0.88 IAI46_18885 phosphoribosylformylglycinamidine cyclo-ligase — —
Erwinia tracheiphila SCR3 0.76 LU632_RS15370 pdxJ pyridoxine 5'-phosphate synthase 0.88 LU632_RS08275 purM phosphoribosylformylglycinamidine cyclo-ligase — —
Kangiella aquimarina DSM 16071 0.75 B158DRAFT_2190 pyridoxine 5'-phosphate synthase 0.70 B158DRAFT_2385 phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) — —
Alteromonas macleodii MIT1002 0.72 MIT1002_00791 Pyridoxine 5'-phosphate synthase 0.73 MIT1002_02219 Phosphoribosylformylglycinamidine cyclo-ligase — —
Vibrio cholerae E7946 ATCC 55056 0.71 CSW01_12440 pyridoxine 5'-phosphate synthase 0.77 CSW01_11350 phosphoribosylformylglycinamidine cyclo-ligase — —
Shewanella sp. ANA-3 0.67 Shewana3_3023 pyridoxine 5'-phosphate synthase (RefSeq) 0.75 Shewana3_2545 phosphoribosylaminoimidazole synthetase (RefSeq) — —
Shewanella loihica PV-4 0.67 Shew_1057 pyridoxal phosphate biosynthetic protein PdxJ (RefSeq) 0.75 Shew_1513 phosphoribosylaminoimidazole synthetase (RefSeq) — —
Shewanella oneidensis MR-1 0.67 SO1351 pdxJ pyridoxal phosphate biosynthetic protein PdxJ (NCBI ptt file) 0.75 SO2760 purM phosphoribosylformylglycinamidine cyclo-ligase (NCBI ptt file) — —
Shewanella amazonensis SB2B 0.66 Sama_0883 pyridoxine 5'-phosphate synthase (RefSeq) 0.77 Sama_2097 phosphoribosylaminoimidazole synthetase (RefSeq) — —
Paraburkholderia sabiae LMG 24235 0.64 QEN71_RS04625 pyridoxine 5'-phosphate synthase 0.55 QEN71_RS26445 phosphoribosylformylglycinamidine cyclo-ligase — —
Paraburkholderia bryophila 376MFSha3.1 0.64 H281DRAFT_04365 pyridoxine 5'-phosphate synthase 0.54 H281DRAFT_04710 phosphoribosylformylglycinamidine cyclo-ligase — —
Burkholderia phytofirmans PsJN 0.64 BPHYT_RS14355 pyridoxine 5'-phosphate synthase 0.55 BPHYT_RS03640 phosphoribosylformylglycinamidine cyclo-ligase — —
Paraburkholderia graminis OAS925 0.64 ABIE53_003033 pyridoxine 5-phosphate synthase 0.54 ABIE53_000874 phosphoribosylformylglycinamidine cyclo-ligase — —
Pseudomonas sp. RS175 0.63 PFR28_03520 'Pyridoxine 5'-phosphate synthase' transl_table=11 0.68 PFR28_03217 Phosphoribosylformylglycinamidine cyclo-ligase — —
Pseudomonas fluorescens FW300-N1B4 0.63 Pf1N1B4_889 Pyridoxine 5'-phosphate synthase (EC 2.6.99.2) 0.68 Pf1N1B4_3698 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) — —
Pseudomonas putida KT2440 0.63 PP_1436 Pyridoxine 5'-phosphate synthase 0.69 PP_1665 Phosphoribosylformylglycinamidine cyclo-ligase — —
Pseudomonas sp. S08-1 0.63 OH686_20095 pyridoxine 5'-phosphate synthase 0.68 OH686_18995 Phosphoribosylformylglycinamidine cyclo-ligase — —
Pseudomonas fluorescens FW300-N2C3 0.63 AO356_17510 pyridoxine 5'-phosphate synthase 0.69 AO356_19090 phosphoribosylaminoimidazole synthetase — —
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_4837 Pyridoxine 5'-phosphate synthase (EC 2.6.99.2) 0.68 PfGW456L13_4252 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) — —
Pseudomonas syringae pv. syringae B728a 0.62 Psyr_3948 pyridoxine 5'-phosphate synthase 0.69 Psyr_3689 phosphoribosylformylglycinamidine cyclo-ligase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.62 Psyr_3948 pyridoxine 5'-phosphate synthase 0.69 Psyr_3689 phosphoribosylformylglycinamidine cyclo-ligase — —
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_5429 Pyridoxine 5'-phosphate synthase (EC 2.6.99.2) 0.69 Pf6N2E2_5729 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) — —
Pseudomonas fluorescens FW300-N2E3 0.61 AO353_04495 pyridoxine 5'-phosphate synthase 0.68 AO353_02680 phosphoribosylaminoimidazole synthetase — —
Pseudomonas stutzeri RCH2 0.61 Psest_3089 pyridoxine 5'-phosphate synthase 0.70 Psest_1474 phosphoribosylaminoimidazole synthetase — —
Cupriavidus basilensis FW507-4G11 0.61 RR42_RS14025 pyridoxine 5'-phosphate synthase 0.59 RR42_RS17220 phosphoribosylaminoimidazole synthetase — —
Pseudomonas simiae WCS417 0.61 PS417_05205 pyridoxine 5'-phosphate synthase 0.69 PS417_20120 phosphoribosylaminoimidazole synthetase — —
Pseudomonas fluorescens SBW25-INTG 0.60 PFLU_RS05275 pyridoxine 5'-phosphate synthase 0.69 PFLU_RS22065 phosphoribosylformylglycinamidine cyclo-ligase — —
Marinobacter adhaerens HP15 0.60 HP15_787 pyridoxal phosphate biosynthetic protein PdxJ 0.68 HP15_1299 phosphoribosylaminoimidazole synthetase — —
Pseudomonas fluorescens SBW25 0.60 PFLU_RS05275 pyridoxine 5'-phosphate synthase 0.69 PFLU_RS22065 phosphoribosylformylglycinamidine cyclo-ligase — —
Acinetobacter radioresistens SK82 0.60 MPMX26_02152 Pyridoxine 5'-phosphate synthase 0.67 MPMX26_02206 Phosphoribosylformylglycinamidine cyclo-ligase — —
Ralstonia solanacearum IBSBF1503 0.58 RALBFv3_RS14500 pyridoxine 5'-phosphate synthase 0.55 RALBFv3_RS05280 phosphoribosylformylglycinamidine cyclo-ligase — —
Ralstonia solanacearum UW163 0.58 UW163_RS11965 pyridoxine 5'-phosphate synthase 0.55 UW163_RS08345 phosphoribosylformylglycinamidine cyclo-ligase — —
Ralstonia solanacearum GMI1000 0.57 RS_RS05280 pyridoxine 5'-phosphate synthase 0.54 RS_RS13145 phosphoribosylformylglycinamidine cyclo-ligase — —
Ralstonia solanacearum PSI07 0.57 RPSI07_RS18960 pyridoxine 5'-phosphate synthase 0.55 RPSI07_RS12020 phosphoribosylformylglycinamidine cyclo-ligase — —
Herbaspirillum seropedicae SmR1 0.55 HSERO_RS09675 pyridoxine 5'-phosphate synthase 0.56 HSERO_RS03165 phosphoribosylaminoimidazole synthetase — —
Azospirillum sp. SherDot2 0.55 MPMX19_00840 Pyridoxine 5'-phosphate synthase 0.53 MPMX19_01304 Phosphoribosylformylglycinamidine cyclo-ligase low > 112
Phaeobacter inhibens DSM 17395 0.55 PGA1_c01030 pyridoxine 5'-phosphate synthase PdxJ 0.52 PGA1_c13260 phosphoribosylformylglycinamidine cyclo-ligase PurM — —
Ralstonia sp. UNC404CL21Col 0.55 ABZR87_RS10220 pyridoxine 5'-phosphate synthase 0.55 ABZR87_RS00915 phosphoribosylformylglycinamidine cyclo-ligase — —
Dinoroseobacter shibae DFL-12 0.54 Dshi_0196 pyridoxal phosphate biosynthetic protein PdxJ (RefSeq) 0.49 Dshi_1889 phosphoribosylformylglycinamidine cyclo-ligase (RefSeq) — —
Azospirillum brasilense Sp245 0.54 AZOBR_RS22055 pyridoxine 5'-phosphate synthase 0.54 AZOBR_RS16290 phosphoribosylaminoimidazole synthetase low > 97
Dechlorosoma suillum PS 0.53 Dsui_2463 pyridoxine 5''-phosphate synthase 0.62 Dsui_1519 phosphoribosylaminoimidazole synthetase — —
Magnetospirillum magneticum AMB-1 0.53 AMB_RS11405 pyridoxine 5'-phosphate synthase 0.52 AMB_RS14330 phosphoribosylformylglycinamidine cyclo-ligase — —
Bosea sp. OAE506 0.52 ABIE41_RS19905 pyridoxine 5'-phosphate synthase 0.48 ABIE41_RS17040 phosphoribosylformylglycinamidine cyclo-ligase low > 77
Synechococcus elongatus PCC 7942 0.52 Synpcc7942_1194 pdxJ pyridoxal phosphate biosynthetic protein PdxJ 0.53 Synpcc7942_0851 purM phosphoribosylaminoimidazole synthetase — —
Caulobacter crescentus NA1000 0.52 CCNA_01626 pyridoxal phosphate biosynthetic protein pdxJ 0.50 CCNA_01775 phosphoribosylformylglycinamidine cyclo-ligase — —
Caulobacter crescentus NA1000 Δfur 0.52 CCNA_01626 pyridoxal phosphate biosynthetic protein pdxJ 0.50 CCNA_01775 phosphoribosylformylglycinamidine cyclo-ligase — —
Desulfovibrio vulgaris Hildenborough JW710 0.51 DVU1908 pdxJ pyridoxal phosphate biosynthetic protein PdxJ (TIGR) 0.48 DVU1406 purM phosphoribosylformylglycinamidine cyclo-ligase (TIGR) — —
Desulfovibrio vulgaris Miyazaki F 0.51 DvMF_0281 pyridoxine 5'-phosphate synthase (RefSeq) 0.49 DvMF_0202 phosphoribosylaminoimidazole synthetase (RefSeq) — —
Rhodospirillum rubrum S1H 0.50 Rru_A1854 Pyridoxal phosphate biosynthetic protein PdxJ (NCBI) 0.56 Rru_A2167 Phosphoribosylformylglycinamidine cyclo-ligase (NCBI) low > 58
Sphingomonas koreensis DSMZ 15582 0.50 Ga0059261_2011 pyridoxine 5'-phosphate synthase 0.51 Ga0059261_0228 phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) — —
Castellaniella sp019104865 MT123 0.49 ABCV34_RS04215 pyridoxine 5'-phosphate synthase 0.56 ABCV34_RS08795 phosphoribosylformylglycinamidine cyclo-ligase — —
Rhodopseudomonas palustris CGA009 0.48 TX73_013960 pyridoxine 5'-phosphate synthase 0.47 TX73_015785 phosphoribosylformylglycinamidine cyclo-ligase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.42 A4249_RS05520 pyridoxine 5'-phosphate synthase 0.48 A4249_RS08210 phosphoribosylformylglycinamidine cyclo-ligase — —
Bacteroides ovatus ATCC 8483 0.34 BACOVA_01142 pyridoxine 5'-phosphate synthase 0.09 BACOVA_05058 hypothetical protein 0.65 76
Bacteroides stercoris CC31F 0.33 HMPREF1181_RS06645 pyridoxine 5'-phosphate synthase 0.10 HMPREF1181_RS06340 phosphoribosylformylglycinamidine cyclo-ligase — —
Bacteroides thetaiotaomicron VPI-5482 0.33 BT3918 pyridoxal phosphate biosynthetic protein pdxJ (NCBI ptt file) 0.10 BT4211 putative phosphoribosylformylglycinamidine cyclo-ligase (NCBI ptt file) low > 81
Phocaeicola vulgatus CL09T03C04 0.33 HMPREF1058_RS08325 pyridoxine 5'-phosphate synthase 0.09 HMPREF1058_RS08025 phosphoribosylformylglycinamidine cyclo-ligase low > 67
Phocaeicola dorei CL03T12C01 0.33 ABI39_RS02500 pyridoxine 5'-phosphate synthase 0.10 ABI39_RS00475 phosphoribosylformylglycinamidine cyclo-ligase 0.72 33
Agrobacterium fabrum C58 0.31 Atu2024 pyridoxal phosphate biosynthesis protein 0.53 Atu1141 Phosphoribosylglycinamide synthetase — —
Pedobacter sp. GW460-11-11-14-LB5 0.30 CA265_RS25170 pyridoxine 5'-phosphate synthase 0.09 CA265_RS05175 phosphoribosylformylglycinamidine cyclo-ligase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.30 CA264_15275 pyridoxine 5'-phosphate synthase 0.08 CA264_17695 phosphoribosylformylglycinamidine cyclo-ligase — —
Parabacteroides merdae CL09T00C40 0.30 HMPREF1078_RS10265 pyridoxine 5'-phosphate synthase 0.10 HMPREF1078_RS13965 AIR synthase-related protein low > 61
Echinicola vietnamensis KMM 6221, DSM 17526 0.30 Echvi_0661 pyridoxine 5'-phosphate synthase 0.08 Echvi_0734 Phosphoribosylaminoimidazole (AIR) synthetase — —
Dyella japonica UNC79MFTsu3.2 0.29 ABZR86_RS15180 pyridoxine 5'-phosphate synthase 0.53 ABZR86_RS19865 phosphoribosylformylglycinamidine cyclo-ligase — —
Rhodanobacter denitrificans MT42 0.29 LRK55_RS08205 pyridoxine 5'-phosphate synthase 0.56 LRK55_RS12645 phosphoribosylformylglycinamidine cyclo-ligase — —
Rhodanobacter denitrificans FW104-10B01 0.29 LRK54_RS08440 pyridoxine 5'-phosphate synthase 0.56 LRK54_RS12945 phosphoribosylformylglycinamidine cyclo-ligase — —
Sinorhizobium meliloti 1021 0.28 SMc01407 pyridoxine 5'-phosphate synthase 0.51 SMc00615 phosphoribosylaminoimidazole synthetase — —
Xanthomonas campestris pv. campestris strain 8004 0.28 Xcc-8004.17.1 Pyridoxine 5'-phosphate synthase (EC 2.6.99.2) 0.54 Xcc-8004.1676.1 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.63 53
Rhodanobacter sp. FW510-T8 0.28 OKGIIK_15220 pyridoxine 5'-phosphate synthase 0.53 OKGIIK_02315 purM phosphoribosylformylglycinamidine cyclo-ligase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.27 GFF3349 Pyridoxine 5'-phosphate synthase (EC 2.6.99.2) 0.55 GFF3433 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) — —
Lysobacter sp. OAE881 0.26 ABIE51_RS00810 pyridoxine 5'-phosphate synthase 0.54 ABIE51_RS15890 phosphoribosylformylglycinamidine cyclo-ligase — —
Rhizobium sp. OAE497 0.26 ABIE40_RS11420 pyridoxine 5'-phosphate synthase 0.53 ABIE40_RS06560 phosphoribosylformylglycinamidine cyclo-ligase — —
Acidovorax sp. GW101-3H11 0.25 Ac3H11_1563 Pyridoxine 5'-phosphate synthase (EC 2.6.99.2) 0.55 Ac3H11_1318 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) — —
Variovorax sp. SCN45 0.23 GFF3873 Pyridoxine 5'-phosphate synthase (EC 2.6.99.2) 0.55 GFF3941 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) — —
Variovorax sp. OAS795 0.22 ABID97_RS08380 pyridoxine 5'-phosphate synthase 0.55 ABID97_RS08700 phosphoribosylformylglycinamidine cyclo-ligase — —

Not shown: 1 genomes with orthologs for HEPCGN_20570 only; 5 genomes with orthologs for HEPCGN_20975 only