Conservation of cofitness between PS417_03925 and PS417_23110 in Pseudomonas simiae WCS417

91 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas simiae WCS417 1.0 PS417_03925 nicotinate-nucleotide pyrophosphorylase 1.0 PS417_23110 2-isopropylmalate synthase 0.54 6
Pseudomonas fluorescens SBW25 0.99 PFLU_RS03970 carboxylating nicotinate-nucleotide diphosphorylase 1.00 PFLU_RS24765 2-isopropylmalate synthase low > 109
Pseudomonas fluorescens SBW25-INTG 0.99 PFLU_RS03970 carboxylating nicotinate-nucleotide diphosphorylase 1.00 PFLU_RS24765 2-isopropylmalate synthase 0.50 9
Pseudomonas fluorescens FW300-N1B4 0.94 Pf1N1B4_1153 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.95 Pf1N1B4_847 2-isopropylmalate synthase (EC 2.3.3.13) low > 87
Pseudomonas fluorescens FW300-N2E3 0.93 AO353_05520 nicotinate-nucleotide pyrophosphorylase 0.94 AO353_15925 2-isopropylmalate synthase 0.43 23
Pseudomonas sp. RS175 0.92 PFR28_00098 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.93 PFR28_00305 2-isopropylmalate synthase low > 88
Pseudomonas fluorescens GW456-L13 0.90 PfGW456L13_5082 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.94 PfGW456L13_4854 2-isopropylmalate synthase (EC 2.3.3.13) 0.61 27
Pseudomonas syringae pv. syringae B728a ΔmexB 0.90 Psyr_0815 nicotinate-nucleotide pyrophosphorylase (carboxylating) 0.89 Psyr_1257 2-isopropylmalate synthase low > 86
Pseudomonas syringae pv. syringae B728a 0.90 Psyr_0815 nicotinate-nucleotide pyrophosphorylase (carboxylating) 0.89 Psyr_1257 2-isopropylmalate synthase 0.73 7
Pseudomonas fluorescens FW300-N2E2 0.89 Pf6N2E2_3346 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.93 Pf6N2E2_3170 2-isopropylmalate synthase (EC 2.3.3.13) 0.49 7
Pseudomonas fluorescens FW300-N2C3 0.89 AO356_07370 nicotinate-nucleotide pyrophosphorylase 0.93 AO356_06550 2-isopropylmalate synthase 0.41 43
Pseudomonas putida KT2440 0.86 PP_0787 quinolinate phosphoribosyltransferase (decarboxylating) monomer 0.91 PP_1025 2-isopropylmalate synthase 0.63 28
Pseudomonas stutzeri RCH2 0.83 Psest_0718 nicotinate-nucleotide pyrophosphorylase 0.81 Psest_1277 2-isopropylmalate synthase, yeast type 0.36 58
Pseudomonas sp. S08-1 0.78 OH686_16520 nicotinate-nucleotide diphosphorylase (carboxylating) 0.77 OH686_17570 2-isopropylmalate synthase 0.63 52
Marinobacter adhaerens HP15 0.71 HP15_1305 nicotinate-nucleotide pyrophosphorylase 0.52 HP15_2055 2-isopropylmalate synthase — —
Dechlorosoma suillum PS 0.56 Dsui_2901 nicotinate-nucleotide pyrophosphorylase 0.59 Dsui_3227 2-isopropylmalate synthase — —
Shewanella amazonensis SB2B 0.56 Sama_0371 nicotinate-nucleotide diphosphorylase (carboxylating) (RefSeq) 0.09 Sama_0335 2-isopropylmalate synthase (RefSeq) — —
Dyella japonica UNC79MFTsu3.2 0.56 ABZR86_RS09850 carboxylating nicotinate-nucleotide diphosphorylase 0.09 ABZR86_RS15970 2-isopropylmalate synthase low > 74
Vibrio cholerae E7946 ATCC 55056 0.55 CSW01_12265 carboxylating nicotinate-nucleotide diphosphorylase 0.10 CSW01_12595 2-isopropylmalate synthase low > 62
Shewanella loihica PV-4 0.54 Shew_3435 nicotinate-nucleotide pyrophosphorylase (RefSeq) 0.09 Shew_3472 2-isopropylmalate synthase (RefSeq) — —
Acinetobacter radioresistens SK82 0.54 MPMX26_00042 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.60 MPMX26_00404 2-isopropylmalate synthase low > 36
Shewanella sp. ANA-3 0.53 Shewana3_0422 nicotinate-nucleotide pyrophosphorylase [carboxylating] (RefSeq) 0.09 Shewana3_3761 2-isopropylmalate synthase (RefSeq) — —
Dickeya dadantii 3937 0.53 DDA3937_RS17955 carboxylating nicotinate-nucleotide diphosphorylase 0.50 DDA3937_RS02895 2-isopropylmalate synthase low > 74
Alteromonas macleodii MIT1002 0.53 MIT1002_03008 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.10 MIT1002_00949 2-isopropylmalate synthase — —
Rhodanobacter denitrificans MT42 0.53 LRK55_RS13510 carboxylating nicotinate-nucleotide diphosphorylase 0.09 LRK55_RS09985 2-isopropylmalate synthase low > 63
Dickeya dianthicola ME23 0.52 DZA65_RS19035 carboxylating nicotinate-nucleotide diphosphorylase 0.10 DZA65_RS19200 2-isopropylmalate synthase 0.80 20
Rhodanobacter denitrificans FW104-10B01 0.52 LRK54_RS13795 carboxylating nicotinate-nucleotide diphosphorylase 0.09 LRK54_RS10345 2-isopropylmalate synthase low > 59
Pectobacterium carotovorum WPP14 0.52 HER17_RS03250 carboxylating nicotinate-nucleotide diphosphorylase 0.09 HER17_RS03085 2-isopropylmalate synthase 0.90 14
Rahnella sp. WP5 0.52 EX31_RS03515 carboxylating nicotinate-nucleotide diphosphorylase 0.56 EX31_RS24130 2-isopropylmalate synthase low > 89
Dickeya dianthicola 67-19 0.52 HGI48_RS17890 carboxylating nicotinate-nucleotide diphosphorylase 0.10 HGI48_RS18055 2-isopropylmalate synthase 0.61 28
Hydrogenophaga sp. GW460-11-11-14-LB1 0.52 GFF1217 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.61 GFF4280 2-isopropylmalate synthase (EC 2.3.3.13) low > 90
Castellaniella sp019104865 MT123 0.51 ABCV34_RS03695 carboxylating nicotinate-nucleotide diphosphorylase 0.60 ABCV34_RS12420 2-isopropylmalate synthase low > 48
Ralstonia solanacearum PSI07 0.51 RPSI07_RS12655 nicotinate-nucleotide diphosphorylase (carboxylating) 0.63 RPSI07_RS01320 2-isopropylmalate synthase low > 81
Ralstonia solanacearum UW163 0.50 UW163_RS08940 nicotinate-nucleotide diphosphorylase (carboxylating) 0.64 UW163_RS17345 2-isopropylmalate synthase — —
Ralstonia solanacearum IBSBF1503 0.50 RALBFv3_RS04730 nicotinate-nucleotide diphosphorylase (carboxylating) 0.64 RALBFv3_RS21840 2-isopropylmalate synthase low > 76
Ralstonia sp. UNC404CL21Col 0.50 ABZR87_RS00350 carboxylating nicotinate-nucleotide diphosphorylase 0.62 ABZR87_RS22365 2-isopropylmalate synthase low > 80
Acidovorax sp. GW101-3H11 0.50 Ac3H11_3838 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.54 Ac3H11_5000 2-isopropylmalate synthase (EC 2.3.3.13) low > 79
Cupriavidus basilensis FW507-4G11 0.49 RR42_RS17015 nicotinate-nucleotide pyrophosphorylase 0.62 RR42_RS21205 2-isopropylmalate synthase low > 128
Herbaspirillum seropedicae SmR1 0.49 HSERO_RS11070 nicotinate-nucleotide pyrophosphorylase 0.66 HSERO_RS17185 2-isopropylmalate synthase 0.83 6
Serratia liquefaciens MT49 0.49 IAI46_03530 carboxylating nicotinate-nucleotide diphosphorylase 0.57 IAI46_09630 2-isopropylmalate synthase low > 86
Paraburkholderia sabiae LMG 24235 0.49 QEN71_RS03065 carboxylating nicotinate-nucleotide diphosphorylase 0.57 QEN71_RS01640 2-isopropylmalate synthase low > 153
Burkholderia phytofirmans PsJN 0.48 BPHYT_RS15645 nicotinate-nucleotide pyrophosphorylase 0.63 BPHYT_RS13280 2-isopropylmalate synthase low > 109
Pantoea sp. MT58 0.48 IAI47_15845 carboxylating nicotinate-nucleotide diphosphorylase 0.52 IAI47_10235 2-isopropylmalate synthase low > 76
Variovorax sp. OAS795 0.48 ABID97_RS07410 carboxylating nicotinate-nucleotide diphosphorylase 0.59 ABID97_RS14905 2-isopropylmalate synthase low > 91
Enterobacter asburiae PDN3 0.48 EX28DRAFT_3702 nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) 0.55 EX28DRAFT_2770 2-isopropylmalate synthase, yeast type low > 76
Paraburkholderia graminis OAS925 0.48 ABIE53_003293 nicotinate-nucleotide pyrophosphorylase (carboxylating) 0.61 ABIE53_002867 2-isopropylmalate synthase low > 113
Enterobacter sp. TBS_079 0.48 MPMX20_00800 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.55 MPMX20_03565 2-isopropylmalate synthase low > 85
Escherichia coli HS(pFamp)R (ATCC 700891) 0.48 OHPLBJKB_03552 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.09 OHPLBJKB_03583 2-isopropylmalate synthase low > 73
Escherichia coli BL21 0.48 ECD_00108 quinolinate phosphoribosyltransferase 0.09 ECD_00076 2-isopropylmalate synthase low > 60
Escherichia coli ECOR27 0.48 NOLOHH_02875 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.09 NOLOHH_03060 2-isopropylmalate synthase low > 57
Escherichia coli BW25113 0.48 b0109 nadC nicotinate-nucleotide pyrophosphorylase (NCBI) 0.09 b0074 leuA 2-isopropylmalate synthase (NCBI) 0.64 26
Escherichia coli ECOR38 0.48 HEPCGN_08510 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.09 HEPCGN_08695 2-isopropylmalate synthase low > 85
Escherichia coli ECRC101 0.48 OKFHMN_10530 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.09 OKFHMN_10715 2-isopropylmalate synthase — —
Escherichia coli ECRC98 0.48 JDDGAC_14125 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.09 JDDGAC_14310 2-isopropylmalate synthase — —
Escherichia coli ECRC99 0.48 KEDOAH_17625 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.09 KEDOAH_17440 2-isopropylmalate synthase — —
Escherichia coli Nissle 1917 0.48 ECOLIN_RS00585 carboxylating nicotinate-nucleotide diphosphorylase 0.09 ECOLIN_RS00400 2-isopropylmalate synthase low > 52
Escherichia fergusonii Becca 0.48 EFB2_03940 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.09 EFB2_03971 2-isopropylmalate synthase low > 86
Escherichia coli ECRC102 0.48 NIAGMN_08380 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.09 NIAGMN_08565 2-isopropylmalate synthase — —
Escherichia coli ECRC101 0.48 MCAODC_01045 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.09 MCAODC_01230 2-isopropylmalate synthase — —
Escherichia coli ECRC62 0.48 BNILDI_08735 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.09 BNILDI_08550 2-isopropylmalate synthase — —
Ralstonia solanacearum GMI1000 0.47 RS_RS12290 nicotinate-nucleotide diphosphorylase (carboxylating) 0.62 RS_RS18695 2-isopropylmalate synthase 2 low > 80
Klebsiella michiganensis M5al 0.47 BWI76_RS04845 nicotinate-nucleotide pyrophosphorylase 0.53 BWI76_RS22105 2-isopropylmalate synthase low > 92
Paraburkholderia bryophila 376MFSha3.1 0.46 H281DRAFT_04070 nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.62 H281DRAFT_00385 2-isopropylmalate synthase 0.33 91
Variovorax sp. SCN45 0.45 GFF2574 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.60 GFF1164 2-isopropylmalate synthase (EC 2.3.3.13) low > 127
Erwinia tracheiphila SCR3 0.45 LU632_RS03040 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.10 LU632_RS02880 leuA 2-isopropylmalate synthase low > 74
Bosea sp. OAE506 0.42 ABIE41_RS02500 carboxylating nicotinate-nucleotide diphosphorylase 0.11 ABIE41_RS13000 2-isopropylmalate synthase low > 77
Xanthomonas campestris pv. campestris strain 8004 0.42 Xcc-8004.2009.1 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.10 Xcc-8004.1056.1 2-isopropylmalate synthase (EC 2.3.3.13) low > 74
Lysobacter sp. OAE881 0.40 ABIE51_RS15405 carboxylating nicotinate-nucleotide diphosphorylase 0.09 ABIE51_RS17570 2-isopropylmalate synthase low > 62
Magnetospirillum magneticum AMB-1 0.40 AMB_RS19655 nicotinate-nucleotide diphosphorylase (carboxylating) 0.56 AMB_RS17550 2-isopropylmalate synthase — —
Phocaeicola dorei CL03T12C01 0.39 ABI39_RS11900 carboxylating nicotinate-nucleotide diphosphorylase 0.11 ABI39_RS10195 2-isopropylmalate synthase — —
Phocaeicola vulgatus CL09T03C04 0.39 HMPREF1058_RS15940 carboxylating nicotinate-nucleotide diphosphorylase 0.11 HMPREF1058_RS14545 2-isopropylmalate synthase — —
Parabacteroides merdae CL09T00C40 0.38 HMPREF1078_RS16725 carboxylating nicotinate-nucleotide diphosphorylase 0.12 HMPREF1078_RS16665 2-isopropylmalate synthase — —
Caulobacter crescentus NA1000 0.37 CCNA_03009 nicotinate-nucleotide pyrophosphorylase 0.09 CCNA_01610 2-isopropylmalate synthase — —
Caulobacter crescentus NA1000 Δfur 0.37 CCNA_03009 nicotinate-nucleotide pyrophosphorylase 0.09 CCNA_01610 2-isopropylmalate synthase — —
Rhodopseudomonas palustris CGA009 0.37 TX73_005415 carboxylating nicotinate-nucleotide diphosphorylase 0.56 TX73_024250 2-isopropylmalate synthase — —
Rhodospirillum rubrum S1H 0.36 Rru_A1432 Nicotinate-nucleotide pyrophosphorylase (NCBI) 0.55 Rru_A1461 2-isopropylmalate synthase (RefSeq) low > 58
Bacteroides ovatus ATCC 8483 0.36 BACOVA_04303 nicotinate-nucleotide diphosphorylase (carboxylating) 0.11 BACOVA_04604 2-isopropylmalate synthase 0.85 28
Bacteroides stercoris CC31F 0.36 HMPREF1181_RS10745 carboxylating nicotinate-nucleotide diphosphorylase 0.11 HMPREF1181_RS14150 2-isopropylmalate synthase — —
Agrobacterium fabrum C58 0.36 Atu4096 nicotinate-nucleotide pyrophosphorylase 0.53 Atu2264 2-isopropylmalate synthase 0.78 17
Rhizobium sp. OAE497 0.35 ABIE40_RS23265 carboxylating nicotinate-nucleotide diphosphorylase 0.50 ABIE40_RS13330 2-isopropylmalate synthase 0.59 8
Bifidobacterium breve UCC2003 0.35 BBR_RS16720 nicotinate-nucleotide diphosphorylase (carboxylating) 0.50 BBR_RS11170 2-isopropylmalate synthase low > 34
Bacteroides thetaiotaomicron VPI-5482 0.35 BT1560 nicotinate-nucleotide pyrophosphorylase (NCBI ptt file) 0.10 BT1861 2-isopropylmalate synthase (EC 2.3.3.13) (from data) — —
Sphingomonas koreensis DSMZ 15582 0.35 Ga0059261_0061 nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) 0.57 Ga0059261_4031 2-isopropylmalate synthase, yeast type — —
Azospirillum sp. SherDot2 0.35 MPMX19_05672 putative nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.56 MPMX19_01822 2-isopropylmalate synthase — —
Sinorhizobium meliloti 1021 0.34 SMc02598 nicotinate-nucleotide pyrophosphorylase carboxylating protein 0.52 SMc02717 2-isopropylmalate synthase low > 103
Phaeobacter inhibens DSM 17395 0.33 PGA1_c27810 nicotinate-nucleotide pyrophosphorylase 0.09 PGA1_c26470 2-isopropylmalate synthase LeuA low > 62
Mycobacterium tuberculosis H37Rv 0.32 Rv1596 Probable nicotinate-nucleotide pyrophosphatase NadC 0.51 Rv3710 2-isopropylmalate synthase LeuA (alpha-isopropylmalate synthase) (alpha-IPM synthetase) (IPMS) — —
Synechococcus elongatus PCC 7942 0.30 Synpcc7942_0951 nadC nicotinate-nucleotide pyrophosphorylase 0.09 Synpcc7942_1410 leuA 2-isopropylmalate synthase — —
Desulfovibrio vulgaris Hildenborough JW710 0.29 DVU1807 nadC nicotinate-nucleotide pyrophosphorylase (TIGR) 0.10 DVU2981 leuA 2-isopropylmalate synthase (TIGR) — —
Desulfovibrio vulgaris Miyazaki F 0.27 DvMF_0524 nicotinate-nucleotide pyrophosphorylase (RefSeq) 0.11 DvMF_1791 2-isopropylmalate synthase (RefSeq) — —
Methanococcus maripaludis S2 0.26 MMP_RS04560 carboxylating nicotinate-nucleotide diphosphorylase 0.09 MMP_RS05500 2-isopropylmalate synthase — —
Methanococcus maripaludis JJ 0.26 MMJJ_RS00575 carboxylating nicotinate-nucleotide diphosphorylase 0.09 MMJJ_RS08870 2-isopropylmalate synthase — —

Not shown: 8 genomes with orthologs for PS417_03925 only; 4 genomes with orthologs for PS417_23110 only