Conservation of cofitness between PGA1_c29490 and PGA1_c29830 in Phaeobacter inhibens DSM 17395

97 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Phaeobacter inhibens DSM 17395 1.0 PGA1_c29490 dihydroxy-acid dehydratase LivD 1.0 PGA1_c29830 3-isopropylmalate dehydrogenase LeuB 0.94 2
Sinorhizobium meliloti 1021 0.77 SMc04045 dihydroxy-acid dehydratase 0.59 SMc04405 3-isopropylmalate dehydrogenase 0.97 10
Rhizobium sp. OAE497 0.76 ABIE40_RS08005 dihydroxy-acid dehydratase 0.59 ABIE40_RS19050 3-isopropylmalate dehydrogenase 0.86 35
Agrobacterium fabrum C58 0.76 Atu1918 dihydroxy-acid dehydratase 0.58 Atu2791 3-isopropylmalate dehydrogenase — —
Rhodopseudomonas palustris CGA009 0.76 TX73_007515 dihydroxy-acid dehydratase 0.56 TX73_001175 3-isopropylmalate dehydrogenase — —
Pseudomonas fluorescens GW456-L13 0.75 PfGW456L13_973 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.59 PfGW456L13_3945 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.89 11
Pseudomonas fluorescens FW300-N2E3 0.75 AO353_08345 dihydroxy-acid dehydratase 0.58 AO353_20635 3-isopropylmalate dehydrogenase 0.97 4
Pseudomonas fluorescens SBW25 0.75 PFLU_RS28535 dihydroxy-acid dehydratase 0.59 PFLU_RS20565 3-isopropylmalate dehydrogenase 0.77 8
Pseudomonas fluorescens SBW25-INTG 0.75 PFLU_RS28535 dihydroxy-acid dehydratase 0.59 PFLU_RS20565 3-isopropylmalate dehydrogenase 0.86 4
Pseudomonas sp. RS175 0.75 PFR28_04278 Dihydroxy-acid dehydratase 0.57 PFR28_02821 3-isopropylmalate dehydrogenase 0.85 2
Pseudomonas fluorescens FW300-N1B4 0.75 Pf1N1B4_2303 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.58 Pf1N1B4_12 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.92 10
Pseudomonas simiae WCS417 0.74 PS417_26890 dihydroxy-acid dehydratase 0.58 PS417_18585 3-isopropylmalate dehydrogenase 0.91 6
Pseudomonas fluorescens FW300-N2E2 0.74 Pf6N2E2_4564 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.58 Pf6N2E2_66 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.95 3
Pseudomonas fluorescens FW300-N2C3 0.74 AO356_13250 dihydroxy-acid dehydratase 0.58 AO356_21415 3-isopropylmalate dehydrogenase 0.96 10
Pseudomonas sp. S08-1 0.74 OH686_14100 dihydroxy-acid dehydratase 0.56 OH686_04470 3-isopropylmalate dehydrogenase 0.92 3
Pseudomonas putida KT2440 0.74 PP_5128 Dihydroxy-acid dehydratase 0.58 PP_1988 3-isopropylmalate dehydrogenase 0.92 6
Magnetospirillum magneticum AMB-1 0.74 AMB_RS12770 dihydroxy-acid dehydratase 0.59 AMB_RS20570 3-isopropylmalate dehydrogenase — —
Synechococcus elongatus PCC 7942 0.74 Synpcc7942_0626 ilvD dihydroxy-acid dehydratase 0.50 Synpcc7942_1505 leuB 3-isopropylmalate dehydrogenase — —
Pseudomonas syringae pv. syringae B728a 0.74 Psyr_0469 dihydroxyacid dehydratase 0.58 Psyr_1985 3-isopropylmalate dehydrogenase 0.92 13
Pseudomonas syringae pv. syringae B728a ΔmexB 0.74 Psyr_0469 dihydroxyacid dehydratase 0.58 Psyr_1985 3-isopropylmalate dehydrogenase 0.94 6
Pseudomonas stutzeri RCH2 0.74 Psest_0234 dihydroxy-acid dehydratase 0.58 Psest_2589 3-isopropylmalate dehydrogenase — —
Paraburkholderia sabiae LMG 24235 0.73 QEN71_RS21095 dihydroxy-acid dehydratase 0.51 QEN71_RS17620 3-isopropylmalate dehydrogenase low > 153
Ralstonia sp. UNC404CL21Col 0.73 ABZR87_RS00240 dihydroxy-acid dehydratase 0.53 ABZR87_RS14530 3-isopropylmalate dehydrogenase low > 80
Acidovorax sp. GW101-3H11 0.73 Ac3H11_955 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.52 Ac3H11_1528 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.72 27
Azospirillum brasilense Sp245 0.73 AZOBR_RS15015 dihydroxy-acid dehydratase 0.62 AZOBR_RS14130 3-isopropylmalate dehydrogenase low > 97
Xanthomonas campestris pv. campestris strain 8004 0.73 Xcc-8004.451.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.55 Xcc-8004.1053.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.79 23
Vibrio cholerae E7946 ATCC 55056 0.73 CSW01_00140 dihydroxy-acid dehydratase 0.48 CSW01_12600 3-isopropylmalate dehydrogenase low > 62
Paraburkholderia bryophila 376MFSha3.1 0.72 H281DRAFT_05312 dihydroxyacid dehydratase 0.52 H281DRAFT_06072 3-isopropylmalate dehydrogenase low > 103
Azospirillum sp. SherDot2 0.72 MPMX19_05356 Dihydroxy-acid dehydratase 0.63 MPMX19_00607 3-isopropylmalate dehydrogenase — —
Dechlorosoma suillum PS 0.72 Dsui_1122 dihydroxy-acid dehydratase 0.54 Dsui_3198 3-isopropylmalate dehydrogenase — —
Paraburkholderia graminis OAS925 0.72 ABIE53_006513 dihydroxy-acid dehydratase 0.52 ABIE53_004804 3-isopropylmalate dehydrogenase 0.25 100
Caulobacter crescentus NA1000 0.72 CCNA_03139 dihydroxy-acid dehydratase 0.54 CCNA_00193 3-isopropylmalate dehydrogenase 0.96 14
Caulobacter crescentus NA1000 Δfur 0.72 CCNA_03139 dihydroxy-acid dehydratase 0.54 CCNA_00193 3-isopropylmalate dehydrogenase 0.59 29
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.71 GFF2901 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.48 GFF165 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 78
Escherichia fergusonii Becca 0.71 EFB2_04865 Dihydroxy-acid dehydratase 0.48 EFB2_03972 3-isopropylmalate dehydrogenase low > 86
Escherichia coli Nissle 1917 0.71 ECOLIN_RS21665 dihydroxy-acid dehydratase 0.48 ECOLIN_RS00395 3-isopropylmalate dehydrogenase low > 52
Enterobacter sp. TBS_079 0.71 MPMX20_04499 Dihydroxy-acid dehydratase 0.48 MPMX20_00768 3-isopropylmalate dehydrogenase 0.93 30
Escherichia coli BW25113 0.71 b3771 ilvD dihydroxy-acid dehydratase (NCBI) 0.48 b0073 leuB 3-isopropylmalate dehydrogenase (VIMSS) 0.98 3
Alteromonas macleodii MIT1002 0.71 MIT1002_04041 Dihydroxy-acid dehydratase 0.44 MIT1002_00948 3-isopropylmalate dehydrogenase 0.98 24
Escherichia coli ECOR27 0.71 NOLOHH_06775 ilvD dihydroxy-acid dehydratase 0.48 NOLOHH_03065 leuA 2-isopropylmalate synthase low > 57
Escherichia coli ECOR38 0.71 HEPCGN_13350 ilvD dihydroxy-acid dehydratase 0.48 HEPCGN_08700 leuB 3-isopropylmalate dehydrogenase low > 85
Escherichia coli ECRC62 0.71 BNILDI_04750 ilvD dihydroxy-acid dehydratase 0.48 BNILDI_08545 leuA 2-isopropylmalate synthase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.71 OHPLBJKB_04282 Dihydroxy-acid dehydratase 0.48 OHPLBJKB_03584 3-isopropylmalate dehydrogenase low > 73
Escherichia coli BL21 0.71 ECD_03649 dihydroxyacid dehydratase 0.48 ECD_00075 3-isopropylmalate dehydrogenase, NAD(+)-dependent 0.84 5
Escherichia coli ECRC101 0.71 OKFHMN_14640 ilvD dihydroxy-acid dehydratase 0.48 OKFHMN_10720 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli ECRC99 0.71 KEDOAH_13510 ilvD dihydroxy-acid dehydratase 0.48 KEDOAH_17435 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli ECRC102 0.71 NIAGMN_12395 ilvD dihydroxy-acid dehydratase 0.48 NIAGMN_08570 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli ECRC101 0.71 MCAODC_05145 ilvD dihydroxy-acid dehydratase 0.48 MCAODC_01235 leuB 3-isopropylmalate dehydrogenase — —
Enterobacter asburiae PDN3 0.71 EX28DRAFT_4443 dihydroxy-acid dehydratase 0.48 EX28DRAFT_3669 3-isopropylmalate dehydrogenase 0.93 9
Escherichia coli ECRC98 0.71 JDDGAC_18260 ilvD dihydroxy-acid dehydratase 0.48 JDDGAC_14315 leuB 3-isopropylmalate dehydrogenase — —
Pectobacterium carotovorum WPP14 0.71 HER17_RS01075 dihydroxy-acid dehydratase 0.46 HER17_RS03080 3-isopropylmalate dehydrogenase 0.98 9
Klebsiella michiganensis M5al 0.71 BWI76_RS00975 dihydroxy-acid dehydratase 0.48 BWI76_RS04675 3-isopropylmalate dehydrogenase 0.92 17
Pantoea sp. MT58 0.71 IAI47_01035 dihydroxy-acid dehydratase 0.45 IAI47_16005 3-isopropylmalate dehydrogenase 0.98 5
Herbaspirillum seropedicae SmR1 0.70 HSERO_RS02650 dihydroxy-acid dehydratase 0.52 HSERO_RS16500 3-isopropylmalate dehydrogenase 0.94 5
Dickeya dadantii 3937 0.70 DDA3937_RS20155 dihydroxy-acid dehydratase 0.47 DDA3937_RS18120 3-isopropylmalate dehydrogenase low > 74
Burkholderia phytofirmans PsJN 0.70 BPHYT_RS10100 dihydroxy-acid dehydratase 0.52 BPHYT_RS33900 3-isopropylmalate dehydrogenase 0.84 2
Rhodospirillum rubrum S1H 0.70 Rru_A1786 Dihydroxy-acid dehydratase (NCBI) 0.61 Rru_A1191 3-isopropylmalate dehydrogenase (NCBI) 0.89 18
Dickeya dianthicola 67-19 0.70 HGI48_RS20295 dihydroxy-acid dehydratase 0.46 HGI48_RS18060 3-isopropylmalate dehydrogenase 0.87 12
Dickeya dianthicola ME23 0.69 DZA65_RS21335 dihydroxy-acid dehydratase 0.46 DZA65_RS19205 3-isopropylmalate dehydrogenase 0.89 9
Serratia liquefaciens MT49 0.69 IAI46_24345 dihydroxy-acid dehydratase 0.48 IAI46_03350 3-isopropylmalate dehydrogenase 0.61 47
Shewanella sp. ANA-3 0.69 Shewana3_0358 dihydroxy-acid dehydratase (RefSeq) 0.45 Shewana3_3760 3-isopropylmalate dehydrogenase (RefSeq) 0.96 21
Shewanella loihica PV-4 0.69 Shew_0292 dihydroxy-acid dehydratase (RefSeq) 0.45 Shew_3471 3-isopropylmalate dehydrogenase (RefSeq) 0.99 3
Castellaniella sp019104865 MT123 0.69 ABCV34_RS14810 dihydroxy-acid dehydratase 0.52 ABCV34_RS04280 3-isopropylmalate dehydrogenase low > 48
Shewanella amazonensis SB2B 0.69 Sama_3279 dihydroxy-acid dehydratase (RefSeq) 0.44 Sama_0336 3-isopropylmalate dehydrogenase (RefSeq) 0.97 18
Shewanella oneidensis MR-1 0.68 SO4345 ilvD dihydroxy-acid dehydratase (NCBI ptt file) 0.44 SO4235 leuB 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.99 2
Marinobacter adhaerens HP15 0.68 HP15_595 dihydroxy-acid dehydratase 0.55 HP15_1832 3-isopropylmalate dehydrogenase low > 73
Erwinia tracheiphila SCR3 0.68 LU632_RS24400 ilvD dihydroxy-acid dehydratase 0.46 LU632_RS02875 leuB 3-isopropylmalate dehydrogenase 0.89 11
Rahnella sp. WP5 0.66 EX31_RS15005 dihydroxy-acid dehydratase 0.48 EX31_RS03685 3-isopropylmalate dehydrogenase 0.99 2
Parabacteroides merdae CL09T00C40 0.62 HMPREF1078_RS16695 dihydroxy-acid dehydratase 0.36 HMPREF1078_RS16640 3-isopropylmalate dehydrogenase 0.95 6
Phocaeicola dorei CL03T12C01 0.61 ABI39_RS12715 dihydroxy-acid dehydratase 0.34 ABI39_RS10215 3-isopropylmalate dehydrogenase 0.92 4
Phocaeicola vulgatus CL09T03C04 0.61 HMPREF1058_RS16815 dihydroxy-acid dehydratase 0.34 HMPREF1058_RS14565 3-isopropylmalate dehydrogenase low > 67
Hydrogenophaga sp. GW460-11-11-14-LB1 0.61 GFF2073 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.51 GFF3360 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 90
Bacteroides stercoris CC31F 0.61 HMPREF1181_RS08335 dihydroxy-acid dehydratase 0.35 HMPREF1181_RS14125 3-isopropylmalate dehydrogenase 0.94 5
Bacteroides thetaiotaomicron VPI-5482 0.60 BT2078 dihydroxy-acid dehydratase (NCBI ptt file) 0.35 BT1857 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.88 29
Bacteroides ovatus ATCC 8483 0.59 BACOVA_03302 dihydroxy-acid dehydratase 0.35 BACOVA_04600 3-isopropylmalate dehydrogenase 0.98 3
Desulfovibrio vulgaris Hildenborough JW710 0.39 DVU3373 ilvD dihydroxy-acid dehydratase (TIGR) 0.49 DVU2985 leuB 3-isopropylmalate dehydrogenase (TIGR) 0.95 3
Desulfovibrio vulgaris Miyazaki F 0.39 DvMF_2034 dihydroxy-acid dehydratase (RefSeq) 0.50 DvMF_1794 3-isopropylmalate dehydrogenase (RefSeq) 0.86 14
Dinoroseobacter shibae DFL-12 0.32 Dshi_0129 dihydroxy-acid dehydratase (RefSeq) 0.85 Dshi_0081 3-isopropylmalate dehydrogenase (RefSeq) — —
Variovorax sp. OAS795 0.31 ABID97_RS17500 dihydroxy-acid dehydratase 0.52 ABID97_RS08455 3-isopropylmalate dehydrogenase — —
Variovorax sp. SCN45 0.31 GFF471 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.52 GFF3888 3-isopropylmalate dehydrogenase (EC 1.1.1.85) — —
Cupriavidus basilensis FW507-4G11 0.30 RR42_RS16210 dihydroxy-acid dehydratase 0.53 RR42_RS14385 3-isopropylmalate dehydrogenase — —
Ralstonia solanacearum GMI1000 0.30 RS_RS12105 dihydroxy-acid dehydratase 0.53 RS_RS09990 3-isopropylmalate dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.30 RALBFv3_RS04535 dihydroxy-acid dehydratase 0.52 RALBFv3_RS02610 3-isopropylmalate dehydrogenase — —
Ralstonia solanacearum UW163 0.30 UW163_RS09135 dihydroxy-acid dehydratase 0.52 UW163_RS11115 3-isopropylmalate dehydrogenase — —
Ralstonia solanacearum PSI07 0.30 RPSI07_RS12840 dihydroxy-acid dehydratase 0.52 RPSI07_RS14705 3-isopropylmalate dehydrogenase — —
Acinetobacter radioresistens SK82 0.30 MPMX26_03019 Dihydroxy-acid dehydratase 0.54 MPMX26_00348 3-isopropylmalate dehydrogenase 0.93 5
Bosea sp. OAE506 0.30 ABIE41_RS15690 dihydroxy-acid dehydratase 0.58 ABIE41_RS11860 3-isopropylmalate dehydrogenase — —
Sphingomonas koreensis DSMZ 15582 0.29 Ga0059261_4216 Dihydroxyacid dehydratase/phosphogluconate dehydratase 0.49 Ga0059261_3190 3-isopropylmalate dehydrogenase 0.97 32
Mucilaginibacter yixingensis YX-36 DSM 26809 0.28 ABZR88_RS11575 dihydroxy-acid dehydratase 0.44 ABZR88_RS11605 3-isopropylmalate dehydrogenase — —
Rhodanobacter sp. FW510-T8 0.28 OKGIIK_13600 ilvD dihydroxy-acid dehydratase 0.42 OKGIIK_13595 leuB 3-isopropylmalate dehydrogenase low > 52
Echinicola vietnamensis KMM 6221, DSM 17526 0.27 Echvi_2055 dihydroxy-acid dehydratase 0.40 Echvi_2062 3-isopropylmalate dehydrogenase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.27 CA264_06935 dihydroxy-acid dehydratase 0.37 CA264_09445 3-isopropylmalate dehydrogenase low > 74
Pedobacter sp. GW460-11-11-14-LB5 0.27 CA265_RS15795 dihydroxy-acid dehydratase 0.43 CA265_RS15850 3-isopropylmalate dehydrogenase 0.95 9
Dyella japonica UNC79MFTsu3.2 0.27 ABZR86_RS15945 dihydroxy-acid dehydratase 0.39 ABZR86_RS15950 3-isopropylmalate dehydrogenase 0.94 13
Lysobacter sp. OAE881 0.27 ABIE51_RS17540 dihydroxy-acid dehydratase 0.41 ABIE51_RS17585 3-isopropylmalate dehydrogenase 0.97 8
Rhodanobacter denitrificans FW104-10B01 0.26 LRK54_RS10320 dihydroxy-acid dehydratase 0.42 LRK54_RS10325 3-isopropylmalate dehydrogenase 0.91 4
Rhodanobacter denitrificans MT42 0.26 LRK55_RS09960 dihydroxy-acid dehydratase 0.43 LRK55_RS09965 3-isopropylmalate dehydrogenase low > 63
Brevundimonas sp. GW460-12-10-14-LB2 0.25 A4249_RS10030 dihydroxy-acid dehydratase 0.41 A4249_RS09995 3-isopropylmalate dehydrogenase 0.99 12

Not shown: 4 genomes with orthologs for PGA1_c29490 only; 1 genomes with orthologs for PGA1_c29830 only