Conservation of cofitness between PGA1_c24870 and PGA1_c11700 in Phaeobacter inhibens DSM 17395

98 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Phaeobacter inhibens DSM 17395 1.0 PGA1_c24870 phosphoribosylaminoimidazole carboxylase ATPase subunit PurK 1.0 PGA1_c11700 5,10-methylenetetrahydrofolate reductase MetF 0.87 14
Dinoroseobacter shibae DFL-12 0.71 Dshi_0680 phosphoribosylaminoimidazole carboxylase, ATPase subunit (RefSeq) 0.67 Dshi_2080 5,10-methylenetetrahydrofolate reductase (RefSeq)
Caulobacter crescentus NA1000 Δfur 0.51 CCNA_03392 phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit 0.40 CCNA_02224 methylenetetrahydrofolate reductase low > 67
Caulobacter crescentus NA1000 0.51 CCNA_03392 phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit 0.40 CCNA_02224 methylenetetrahydrofolate reductase 0.83 30
Sinorhizobium meliloti 1021 0.50 SMc04002 phosphoribosylaminoimidazole carboxylase ATPase subunit 0.39 SMc01843 5,10-methylenetetrahydrofolate reductase 0.95 14
Agrobacterium fabrum C58 0.49 Atu3755 phosphoribosylaminoimidazole carboxylase ATPase subunit 0.39 Atu2123 methylenetetrahydrofolate reductase 0.53 86
Rhizobium sp. OAE497 0.49 ABIE40_RS16070 5-(carboxyamino)imidazole ribonucleotide synthase 0.42 ABIE40_RS11950 methylenetetrahydrofolate reductase [NAD(P)H] 0.89 3
Azospirillum brasilense Sp245 0.48 AZOBR_RS06140 phosphoribosylaminoimidazole carboxylase 0.45 AZOBR_RS09540 5 10-methylenetetrahydrofolate reductase
Bosea sp. OAE506 0.48 ABIE41_RS09245 5-(carboxyamino)imidazole ribonucleotide synthase 0.46 ABIE41_RS12475 methylenetetrahydrofolate reductase [NAD(P)H] low > 77
Rhodopseudomonas palustris CGA009 0.45 TX73_021645 5-(carboxyamino)imidazole ribonucleotide synthase 0.38 TX73_019175 methylenetetrahydrofolate reductase [NAD(P)H]
Magnetospirillum magneticum AMB-1 0.45 AMB_RS11140 5-(carboxyamino)imidazole ribonucleotide synthase 0.43 AMB_RS02230 methylenetetrahydrofolate reductase
Sphingomonas koreensis DSMZ 15582 0.45 Ga0059261_1428 5-(carboxyamino)imidazole ribonucleotide synthase 0.47 Ga0059261_0992 5,10-methylenetetrahydrofolate reductase, prokaryotic form
Rhodospirillum rubrum S1H 0.45 Rru_A1051 Phosphoribosylaminoimidazole carboxylase, ATPase subunit (NCBI) 0.45 Rru_A1530 5,10-methylenetetrahydrofolate reductase (NCBI) low > 58
Brevundimonas sp. GW460-12-10-14-LB2 0.45 A4249_RS08935 5-(carboxyamino)imidazole ribonucleotide synthase 0.39 A4249_RS07925 methylenetetrahydrofolate reductase [NAD(P)H]
Azospirillum sp. SherDot2 0.42 MPMX19_01418 N5-carboxyaminoimidazole ribonucleotide synthase 0.45 MPMX19_00635 5,10-methylenetetrahydrofolate reductase
Herbaspirillum seropedicae SmR1 0.37 HSERO_RS03370 phosphoribosylaminoimidazole carboxylase 0.31 HSERO_RS21425 5,10-methylenetetrahydrofolate reductase
Pseudomonas sp. RS175 0.37 PFR28_04495 N5-carboxyaminoimidazole ribonucleotide synthase 0.30 PFR28_04202 5,10-methylenetetrahydrofolate reductase
Pseudomonas putida KT2440 0.37 PP_5335 N5-carboxyaminoimidazole ribonucleotide synthase 0.31 PP_4977 5,10-methylenetetrahydrofolate reductase
Pseudomonas stutzeri RCH2 0.37 Psest_4068 phosphoribosylaminoimidazole carboxylase, PurK protein 0.32 Psest_0313 5,10-methylenetetrahydrofolate reductase, prokaryotic form
Pseudomonas fluorescens FW300-N2E2 0.36 Pf6N2E2_4081 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.30 Pf6N2E2_4638 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Paraburkholderia bryophila 376MFSha3.1 0.36 H281DRAFT_04185 5-(carboxyamino)imidazole ribonucleotide synthase 0.34 H281DRAFT_05801 5,10-methylenetetrahydrofolate reductase (NAD(P))
Burkholderia phytofirmans PsJN 0.36 BPHYT_RS16245 phosphoribosylaminoimidazole carboxylase 0.34 BPHYT_RS18705 5,10-methylenetetrahydrofolate reductase low > 109
Paraburkholderia graminis OAS925 0.36 ABIE53_003423 5-(carboxyamino)imidazole ribonucleotide synthase 0.34 ABIE53_000061 methylenetetrahydrofolate reductase (NADPH)
Xanthomonas campestris pv. campestris strain 8004 0.36 Xcc-8004.2012.1 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.33 Xcc-8004.4336.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) low > 74
Dechlorosoma suillum PS 0.36 Dsui_0091 phosphoribosylaminoimidazole carboxylase, PurK protein 0.33 Dsui_0640 5,10-methylenetetrahydrofolate reductase
Lysobacter sp. OAE881 0.36 ABIE51_RS15390 5-(carboxyamino)imidazole ribonucleotide synthase 0.34 ABIE51_RS16490 methylenetetrahydrofolate reductase [NAD(P)H] low > 62
Pseudomonas fluorescens FW300-N2C3 0.36 AO356_11075 phosphoribosylaminoimidazole carboxylase 0.30 AO356_13605 5,10-methylenetetrahydrofolate reductase
Paraburkholderia sabiae LMG 24235 0.36 QEN71_RS02450 5-(carboxyamino)imidazole ribonucleotide synthase 0.35 QEN71_RS28715 methylenetetrahydrofolate reductase [NAD(P)H] 0.59 43
Pseudomonas fluorescens GW456-L13 0.35 PfGW456L13_747 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.30 PfGW456L13_1050 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Pseudomonas sp. S08-1 0.35 OH686_13380 N5-carboxyaminoimidazole ribonucleotide synthase 0.31 OH686_10820 methylenetetrahydrofolate reductase [NAD(P)H]
Marinobacter adhaerens HP15 0.35 HP15_2350 phosphoribosylaminoimidazole carboxylase ATPase subunit 0.34 HP15_2917 5,10-methylenetetrahydrofolate reductase-like protein
Pseudomonas syringae pv. syringae B728a ΔmexB 0.35 Psyr_5047 5-(carboxyamino)imidazole ribonucleotide synthase 0.30 Psyr_0459 5,10-methylenetetrahydrofolate reductase
Pseudomonas syringae pv. syringae B728a 0.35 Psyr_5047 5-(carboxyamino)imidazole ribonucleotide synthase 0.30 Psyr_0459 5,10-methylenetetrahydrofolate reductase
Pseudomonas fluorescens FW300-N1B4 0.34 Pf1N1B4_2028 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.30 Pf1N1B4_2384 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Pseudomonas fluorescens FW300-N2E3 0.34 AO353_09935 phosphoribosylaminoimidazole carboxylase 0.30 AO353_08015 5,10-methylenetetrahydrofolate reductase
Pseudomonas fluorescens SBW25 0.34 PFLU_RS29800 5-(carboxyamino)imidazole ribonucleotide synthase 0.31 PFLU_RS28165 methylenetetrahydrofolate reductase [NAD(P)H]
Pseudomonas simiae WCS417 0.34 PS417_28115 phosphoribosylaminoimidazole carboxylase 0.31 PS417_26510 5,10-methylenetetrahydrofolate reductase
Pseudomonas fluorescens SBW25-INTG 0.34 PFLU_RS29800 5-(carboxyamino)imidazole ribonucleotide synthase 0.31 PFLU_RS28165 methylenetetrahydrofolate reductase [NAD(P)H]
Acinetobacter radioresistens SK82 0.34 MPMX26_03050 N5-carboxyaminoimidazole ribonucleotide synthase 0.31 MPMX26_01002 5,10-methylenetetrahydrofolate reductase low > 36
Variovorax sp. SCN45 0.34 GFF5513 N5-carboxyaminoimidazole ribonucleotide synthase (EC 6.3.4.18) 0.28 GFF2055 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.81 117
Hydrogenophaga sp. GW460-11-11-14-LB1 0.34 GFF2770 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.31 GFF1692 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Rhodanobacter sp. FW510-T8 0.33 OKGIIK_03050 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.35 OKGIIK_11830 metF methylenetetrahydrofolate reductase [NAD(P)H]
Bifidobacterium breve UCC2003 0.33 BBR_RS13300 5-(carboxyamino)imidazole ribonucleotide synthase 0.23 BBR_RS15410 methylenetetrahydrofolate reductase [NAD(P)H] low > 34
Cupriavidus basilensis FW507-4G11 0.33 RR42_RS03230 phosphoribosylaminoimidazole carboxylase 0.35 RR42_RS01385 5,10-methylenetetrahydrofolate reductase
Dyella japonica UNC79MFTsu3.2 0.32 ABZR86_RS09830 5-(carboxyamino)imidazole ribonucleotide synthase 0.37 ABZR86_RS11570 methylenetetrahydrofolate reductase [NAD(P)H]
Variovorax sp. OAS795 0.32 ABID97_RS01700 5-(carboxyamino)imidazole ribonucleotide synthase 0.29 ABID97_RS25015 methylenetetrahydrofolate reductase [NAD(P)H]
Ralstonia solanacearum PSI07 0.32 RPSI07_RS21130 5-(carboxyamino)imidazole ribonucleotide synthase 0.36 RPSI07_RS23495 methylenetetrahydrofolate reductase [NAD(P)H]
Castellaniella sp019104865 MT123 0.32 ABCV34_RS00565 5-(carboxyamino)imidazole ribonucleotide synthase 0.32 ABCV34_RS13550 methylenetetrahydrofolate reductase [NAD(P)H]
Acidovorax sp. GW101-3H11 0.32 Ac3H11_675 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.30 Ac3H11_3045 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Ralstonia solanacearum GMI1000 0.31 RS_RS02885 5-(carboxyamino)imidazole ribonucleotide synthase 0.36 RS_RS00460 methylenetetrahydrofolate reductase [NAD(P)H]
Ralstonia solanacearum UW163 0.31 UW163_RS01410 5-(carboxyamino)imidazole ribonucleotide synthase 0.35 UW163_RS03705 methylenetetrahydrofolate reductase [NAD(P)H]
Ralstonia solanacearum IBSBF1503 0.31 RALBFv3_RS12200 5-(carboxyamino)imidazole ribonucleotide synthase 0.35 RALBFv3_RS09875 methylenetetrahydrofolate reductase [NAD(P)H]
Ralstonia sp. UNC404CL21Col 0.31 ABZR87_RS08090 5-(carboxyamino)imidazole ribonucleotide synthase 0.35 ABZR87_RS04865 methylenetetrahydrofolate reductase [NAD(P)H]
Rhodanobacter denitrificans MT42 0.31 LRK55_RS13530 5-(carboxyamino)imidazole ribonucleotide synthase 0.36 LRK55_RS11765 methylenetetrahydrofolate reductase [NAD(P)H] low > 63
Rhodanobacter denitrificans FW104-10B01 0.31 LRK54_RS13815 5-(carboxyamino)imidazole ribonucleotide synthase 0.36 LRK54_RS12030 methylenetetrahydrofolate reductase [NAD(P)H]
Pantoea sp. MT58 0.30 IAI47_14355 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 IAI47_00890 methylenetetrahydrofolate reductase low > 76
Kangiella aquimarina DSM 16071 0.29 B158DRAFT_0610 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 B158DRAFT_2461 5,10-methylenetetrahydrofolate reductase (NAD(P)) (EC 1.5.1.20)
Escherichia coli ECOR27 0.29 NOLOHH_00830 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.41 NOLOHH_05810 metF methylenetetrahydrofolate reductase low > 57
Escherichia coli BL21 0.29 ECD_00472 N5-carboxyaminoimidazole ribonucleotide synthase 0.41 ECD_03827 5,10-methylenetetrahydrofolate reductase low > 60
Escherichia coli Nissle 1917 0.29 ECOLIN_RS03025 5-(carboxyamino)imidazole ribonucleotide synthase 0.41 ECOLIN_RS22760 methylenetetrahydrofolate reductase low > 52
Escherichia coli ECOR38 0.29 HEPCGN_06480 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.41 HEPCGN_12310 metF methylenetetrahydrofolate reductase low > 85
Escherichia coli ECRC62 0.29 BNILDI_22260 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.41 BNILDI_05725 metF methylenetetrahydrofolate reductase
Escherichia fergusonii Becca 0.29 EFB2_03540 N5-carboxyaminoimidazole ribonucleotide synthase 0.41 EFB2_04672 5,10-methylenetetrahydrofolate reductase low > 86
Echinicola vietnamensis KMM 6221, DSM 17526 0.29 Echvi_0884 phosphoribosylaminoimidazole carboxylase, PurK protein 0.19 Echvi_3637 5,10-methylenetetrahydrofolate reductase, prokaryotic form
Escherichia coli ECRC101 0.28 OKFHMN_07840 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.41 OKFHMN_13665 metF methylenetetrahydrofolate reductase
Escherichia coli ECRC102 0.28 NIAGMN_05895 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.41 NIAGMN_11420 metF methylenetetrahydrofolate reductase
Escherichia coli ECRC101 0.28 MCAODC_27060 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.41 MCAODC_04165 metF methylenetetrahydrofolate reductase
Escherichia coli ECRC98 0.28 JDDGAC_11490 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.41 JDDGAC_17290 metF methylenetetrahydrofolate reductase
Escherichia coli ECRC99 0.28 KEDOAH_20130 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.41 KEDOAH_14495 metF methylenetetrahydrofolate reductase
Escherichia coli BW25113 0.28 b0522 purK phosphoribosylaminoimidazole carboxylase (NCBI) 0.41 b3941 metF 5,10-methylenetetrahydrofolate reductase (NCBI) 0.81 26
Shewanella loihica PV-4 0.28 Shew_1249 phosphoribosylaminoimidazole carboxylase, ATPase subunit (RefSeq) 0.39 Shew_0522 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.66 48
Vibrio cholerae E7946 ATCC 55056 0.28 CSW01_00260 5-(carboxyamino)imidazole ribonucleotide synthase 0.41 CSW01_13560 methylenetetrahydrofolate reductase 0.60 18
Enterobacter asburiae PDN3 0.28 EX28DRAFT_2460 phosphoribosylaminoimidazole carboxylase, PurK protein 0.41 EX28DRAFT_4413 5,10-methylenetetrahydrofolate reductase, prokaryotic form
Escherichia coli HS(pFamp)R (ATCC 700891) 0.28 OHPLBJKB_03159 N5-carboxyaminoimidazole ribonucleotide synthase 0.41 OHPLBJKB_04109 5,10-methylenetetrahydrofolate reductase low > 73
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.28 GFF4438 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.41 GFF2329 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) low > 78
Enterobacter sp. TBS_079 0.28 MPMX20_01097 N5-carboxyaminoimidazole ribonucleotide synthase 0.41 MPMX20_04529 5,10-methylenetetrahydrofolate reductase 0.67 65
Rahnella sp. WP5 0.28 EX31_RS22620 5-(carboxyamino)imidazole ribonucleotide synthase 0.41 EX31_RS14205 methylenetetrahydrofolate reductase 0.81 76
Klebsiella michiganensis M5al 0.28 BWI76_RS07065 5-(carboxyamino)imidazole ribonucleotide synthase 0.41 BWI76_RS00805 5,10-methylenetetrahydrofolate reductase 0.77 35
Erwinia tracheiphila SCR3 0.27 LU632_RS15250 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.39 LU632_RS19630 metF methylenetetrahydrofolate reductase low > 74
Alteromonas macleodii MIT1002 0.26 MIT1002_00522 N5-carboxyaminoimidazole ribonucleotide synthase 0.38 MIT1002_03670 5,10-methylenetetrahydrofolate reductase low > 70
Serratia liquefaciens MT49 0.26 IAI46_05370 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 IAI46_24530 methylenetetrahydrofolate reductase 0.76 27
Dickeya dianthicola 67-19 0.25 HGI48_RS15190 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 HGI48_RS20415 methylenetetrahydrofolate reductase low > 71
Mucilaginibacter yixingensis YX-36 DSM 26809 0.25 ABZR88_RS09290 5-(carboxyamino)imidazole ribonucleotide synthase 0.20 ABZR88_RS20935 methylenetetrahydrofolate reductase [NAD(P)H]
Dickeya dianthicola ME23 0.25 DZA65_RS15995 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 DZA65_RS21460 methylenetetrahydrofolate reductase 0.59 62
Pectobacterium carotovorum WPP14 0.25 HER17_RS06470 5-(carboxyamino)imidazole ribonucleotide synthase 0.41 HER17_RS00950 methylenetetrahydrofolate reductase low > 75
Dickeya dadantii 3937 0.25 DDA3937_RS15110 5-(carboxyamino)imidazole ribonucleotide synthase 0.41 DDA3937_RS00960 methylenetetrahydrofolate reductase low > 74
Shewanella oneidensis MR-1 0.25 SO3555 purK phosphoribosylaminoimidazole carboxylase, ATPase subunit (NCBI ptt file) 0.40 SO4054 metF 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) 0.85 51
Shewanella amazonensis SB2B 0.25 Sama_1063 phosphoribosylaminoimidazole carboxylase ATPase subunit (RefSeq) 0.40 Sama_3169 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.84 33
Pedobacter sp. GW460-11-11-14-LB5 0.25 CA265_RS07745 5-(carboxyamino)imidazole ribonucleotide synthase 0.21 CA265_RS23445 methylenetetrahydrofolate reductase [NAD(P)H]
Shewanella sp. ANA-3 0.24 Shewana3_3156 phosphoribosylaminoimidazole carboxylase ATPase subunit (RefSeq) 0.40 Shewana3_3612 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.87 28
Pontibacter actiniarum KMM 6156, DSM 19842 0.24 CA264_12600 5-(carboxyamino)imidazole ribonucleotide synthase 0.18 CA264_16780 methylenetetrahydrofolate reductase [NAD(P)H] low > 74
Desulfovibrio vulgaris Hildenborough JW710 0.17 DVU0723 purT phosphoribosylglycinamide formyltransferase 2 (TIGR) 0.27 DVU0997 metF 5,10-methylenetetrahydrofolate reductase (TIGR) low > 55
Desulfovibrio vulgaris Miyazaki F 0.16 DvMF_2756 purT phosphoribosylglycinamide formyltransferase 2 (RefSeq) 0.26 DvMF_3034 5,10-methylenetetrahydrofolate reductase (RefSeq)
Phocaeicola vulgatus CL09T03C04 0.16 HMPREF1058_RS17920 formate-dependent phosphoribosylglycinamide formyltransferase 0.21 HMPREF1058_RS13650 methylenetetrahydrofolate reductase [NAD(P)H] low > 67
Phocaeicola dorei CL03T12C01 0.16 ABI39_RS14185 formate-dependent phosphoribosylglycinamide formyltransferase 0.21 ABI39_RS09240 methylenetetrahydrofolate reductase [NAD(P)H] low > 72
Bacteroides stercoris CC31F 0.15 HMPREF1181_RS16250 formate-dependent phosphoribosylglycinamide formyltransferase 0.21 HMPREF1181_RS00120 methylenetetrahydrofolate reductase [NAD(P)H] low > 56
Parabacteroides merdae CL09T00C40 0.15 HMPREF1078_RS10980 formate-dependent phosphoribosylglycinamide formyltransferase 0.18 HMPREF1078_RS07860 methylenetetrahydrofolate reductase [NAD(P)H] 0.30 40
Bacteroides thetaiotaomicron VPI-5482 0.15 BT0704 phosphoribosylglycinamide formyltransferase 2 (NCBI ptt file) 0.21 BT3821 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) low > 81
Bacteroides ovatus ATCC 8483 0.14 BACOVA_02411 phosphoribosylglycinamide formyltransferase 2 0.19 BACOVA_03666 methylenetetrahydrofolate reductase (NAD(P)H) low > 94

Not shown: 4 genomes with orthologs for PGA1_c24870 only; 1 genomes with orthologs for PGA1_c11700 only