| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_12610 | | 3-isopropylmalate dehydratase small subunit | 1.0 | CSW01_05940 | | anthranilate phosphoribosyltransferase | 0.69 | 20 |
| Serratia liquefaciens MT49 | 0.78 | IAI46_03340 | | 3-isopropylmalate dehydratase small subunit | 0.60 | IAI46_14030 | | anthranilate phosphoribosyltransferase | low | > 87 |
| Dickeya dadantii 3937 | 0.78 | DDA3937_RS18130 | | 3-isopropylmalate dehydratase small subunit | 0.63 | DDA3937_RS10475 | | anthranilate phosphoribosyltransferase | 0.66 | 54 |
| Dickeya dianthicola ME23 | 0.76 | DZA65_RS19215 | | 3-isopropylmalate dehydratase small subunit | 0.63 | DZA65_RS10955 | | anthranilate phosphoribosyltransferase | low | > 75 |
| Dickeya dianthicola 67-19 | 0.76 | HGI48_RS18070 | | 3-isopropylmalate dehydratase small subunit | 0.63 | HGI48_RS10475 | | anthranilate phosphoribosyltransferase | low | > 71 |
| Pantoea agglomerans CFBP13505 P0401 | 0.74 | PagCFBP13505_RS12985 | | 3-isopropylmalate dehydratase small subunit | 0.66 | PagCFBP13505_RS07005 | | anthranilate phosphoribosyltransferase | low | > 74 |
| Pantoea sp. MT58 | 0.73 | IAI47_16015 | | 3-isopropylmalate dehydratase small subunit | 0.63 | IAI47_09180 | | anthranilate phosphoribosyltransferase | 0.95 | 24 |
| Rahnella sp. WP5 | 0.73 | EX31_RS03695 | | 3-isopropylmalate dehydratase small subunit | 0.66 | EX31_RS09965 | | anthranilate phosphoribosyltransferase | 0.94 | 33 |
| Shewanella loihica PV-4 | 0.65 | Shew_3469 | | isopropylmalate isomerase small subunit (RefSeq) | 0.50 | Shew_2253 | | anthranilate phosphoribosyltransferase (RefSeq) | 0.93 | 35 |
| Shewanella oneidensis MR-1 | 0.65 | SO4233 | leuD | 3-isopropylmalate dehydratase, small subunit (NCBI ptt file) | 0.49 | SO3021 | trpD | anthranilate phosphoribosyltransferase (NCBI ptt file) | 0.90 | 53 |
| Erwinia tracheiphila HP pepo 2.2 | 0.65 | IJEDHG_06010 | leuD | 3-isopropylmalate dehydratase small subunit | 0.61 | IJEDHG_23500 | | Anthranilate phosphoribosyltransferase | low | > 61 |
| Erwinia amylovora T8 | 0.64 | OLJFJH_01300 | | 3-isopropylmalate dehydratase small subunit | 0.65 | OLJFJH_13485 | | Anthranilate phosphoribosyltransferase | 0.81 | 40 |
| Shewanella sp. ANA-3 | 0.64 | Shewana3_3758 | leuD | isopropylmalate isomerase small subunit (RefSeq) | 0.48 | Shewana3_1518 | trpD | anthranilate phosphoribosyltransferase (RefSeq) | 0.92 | 31 |
| Shewanella amazonensis SB2B | 0.63 | Sama_0338 | leuD | isopropylmalate isomerase small subunit (RefSeq) | 0.48 | Sama_2131 | trpD | anthranilate phosphoribosyltransferase (RefSeq) | 0.88 | 56 |
| Pseudomonas simiae WCS417 | 0.61 | PS417_18595 | | 3-isopropylmalate dehydratase | 0.26 | PS417_25715 | | anthranilate phosphoribosyltransferase | 0.80 | 24 |
| Pseudomonas orientalis W4I3 | 0.61 | QF045_RS20735 | | 3-isopropylmalate dehydratase small subunit | 0.26 | QF045_RS00110 | | anthranilate phosphoribosyltransferase | 0.98 | 20 |
| Pseudomonas stutzeri RCH2 | 0.61 | Psest_2590 | | 3-isopropylmalate dehydratase, small subunit | 0.33 | Psest_3648 | | anthranilate phosphoribosyltransferase | 0.74 | 27 |
| Pseudomonas fluorescens SBW25-INTG | 0.60 | PFLU_RS20575 | | 3-isopropylmalate dehydratase small subunit | 0.26 | PFLU_RS27370 | | anthranilate phosphoribosyltransferase | 0.82 | 9 |
| Pseudomonas sp. SVBP6 | 0.60 | COO64_RS05660 | leuD | 3-isopropylmalate dehydratase small subunit | 0.28 | COO64_RS22415 | trpD | anthranilate phosphoribosyltransferase | 0.95 | 16 |
| Pseudomonas fluorescens SBW25 | 0.60 | PFLU_RS20575 | | 3-isopropylmalate dehydratase small subunit | 0.26 | PFLU_RS27370 | | anthranilate phosphoribosyltransferase | 0.65 | 8 |
| Pseudomonas lactucae CFBP13502 | 0.60 | GEMAOFIL_03947 | | 3-isopropylmalate dehydratase small subunit | 0.26 | GEMAOFIL_05263 | | Anthranilate phosphoribosyltransferase | 0.78 | 32 |
| Pseudomonas putida KT2440 | 0.60 | PP_1986 | | 3-isopropylmalate dehydratase small subunit | 0.31 | PP_0421 | | Anthranilate phosphoribosyltransferase | 0.82 | 14 |
| Pseudomonas segetis P6 | 0.60 | MPMX49_03073 | | 3-isopropylmalate dehydratase small subunit 1 | 0.31 | MPMX49_00891 | | Anthranilate phosphoribosyltransferase | — | — |
| Pseudomonas sp. BP01 | 0.60 | JOY50_RS16625 | leuD | 3-isopropylmalate dehydratase small subunit | 0.30 | JOY50_RS18235 | trpD | anthranilate phosphoribosyltransferase | low | > 84 |
| Pseudomonas fluorescens FW300-N1B4 | 0.59 | Pf1N1B4_14 | | 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) | 0.26 | Pf1N1B4_2548 | | Anthranilate phosphoribosyltransferase (EC 2.4.2.18) | — | — |
| Pseudomonas sp. DMC3 | 0.59 | GFF786 | | 3-isopropylmalate dehydratase small subunit 1 | 0.26 | GFF17 | | Anthranilate phosphoribosyltransferase | low | > 89 |
| Pseudomonas aeruginosa MRSN321 | 0.59 | DY961_RS01325 | leuD;go_component=3-isopropylmalate | 3-isopropylmalate dehydratase small subunit | 0.28 | DY961_RS23195 | trpD;go_function=anthranilate | anthranilate phosphoribosyltransferase | 0.81 | 34 |
| Pseudomonas fluorescens GW456-L13 | 0.59 | PfGW456L13_3947 | | 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) | 0.26 | PfGW456L13_1221 | | Anthranilate phosphoribosyltransferase (EC 2.4.2.18) | 0.88 | 33 |
| Pseudomonas aeruginosa PA14 | 0.59 | IKLFDK_15875 | | 3-isopropylmalate dehydratase small subunit | 0.28 | IKLFDK_22175 | | Anthranilate phosphoribosyltransferase | 0.76 | 36 |
| Pseudomonas aeruginosa PUPa3 | 0.59 | DQ20_RS34230 | leuD;go_component=3-isopropylmalate | 3-isopropylmalate dehydratase small subunit | 0.28 | DQ20_RS36170 | trpD;go_function=anthranilate | anthranilate phosphoribosyltransferase | 0.82 | 40 |
| Pseudomonas fluorescens FW300-N2E3 | 0.59 | AO353_20625 | | 3-isopropylmalate dehydratase | 0.26 | AO353_07215 | | anthranilate phosphoribosyltransferase | 0.93 | 12 |
| Pseudomonas fluorescens FW300-N2E2 | 0.59 | Pf6N2E2_64 | | 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) | 0.26 | Pf6N2E2_4825 | | Anthranilate phosphoribosyltransferase (EC 2.4.2.18) | 0.91 | 10 |
| Pseudomonas sp. RS175 | 0.59 | PFR28_02823 | | 3-isopropylmalate dehydratase small subunit 1 | 0.26 | PFR28_04044 | | Anthranilate phosphoribosyltransferase | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.58 | AO356_21405 | | 3-isopropylmalate dehydratase | 0.25 | AO356_14435 | | anthranilate phosphoribosyltransferase | 0.92 | 14 |
| Acinetobacter radioresistens SK82 | 0.58 | MPMX26_00346 | | 3-isopropylmalate dehydratase small subunit 1 | 0.33 | MPMX26_00984 | | Anthranilate phosphoribosyltransferase | 0.94 | 12 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.58 | Xcc-8004.1050.1 | | 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) | 0.30 | Xcc-8004.621.1 | | Anthranilate phosphoribosyltransferase (EC 2.4.2.18) | 0.92 | 1 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.58 | H281DRAFT_06073 | | 3-isopropylmalate dehydratase, small subunit | 0.34 | H281DRAFT_05713 | | anthranilate phosphoribosyltransferase | 0.62 | 12 |
| Marinobacter adhaerens HP15 | 0.58 | HP15_1833 | | isopropylmalate isomerase small subunit | 0.30 | HP15_3290 | | anthranilate phosphoribosyltransferase | 0.82 | 20 |
| Pseudomonas syringae pv. syringae B728a | 0.57 | Psyr_1984 | | 3-isopropylmalate dehydratase, small subunit | 0.30 | Psyr_4580 | | anthranilate phosphoribosyltransferase | 0.71 | 37 |
| Alteromonas macleodii MIT1002 | 0.57 | MIT1002_00946 | | 3-isopropylmalate dehydratase small subunit 1 | 0.54 | MIT1002_01428 | | Anthranilate synthase component II | 0.89 | 47 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.57 | Psyr_1984 | | 3-isopropylmalate dehydratase, small subunit | 0.30 | Psyr_4580 | | anthranilate phosphoribosyltransferase | 0.69 | 62 |
| Burkholderia phytofirmans PsJN | 0.57 | BPHYT_RS33905 | | 3-isopropylmalate dehydratase small subunit | 0.33 | BPHYT_RS17400 | | anthranilate phosphoribosyltransferase | 0.72 | 15 |
| Paraburkholderia sabiae LMG 24235 | 0.57 | QEN71_RS17615 | | 3-isopropylmalate dehydratase small subunit | 0.33 | QEN71_RS27560 | | anthranilate phosphoribosyltransferase | 0.75 | 36 |
| Ralstonia solanacearum PSI07 | 0.57 | RPSI07_RS14700 | | 3-isopropylmalate dehydratase small subunit | 0.34 | RPSI07_RS02570 | | anthranilate phosphoribosyltransferase | — | — |
| Ralstonia solanacearum UW163 | 0.57 | UW163_RS11110 | | 3-isopropylmalate dehydratase small subunit | 0.33 | UW163_RS18880 | | anthranilate phosphoribosyltransferase | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.57 | RALBFv3_RS02615 | | 3-isopropylmalate dehydratase small subunit | 0.33 | RALBFv3_RS20295 | | anthranilate phosphoribosyltransferase | low | > 76 |
| Cupriavidus basilensis FW507-4G11 | 0.56 | RR42_RS24180 | | 3-isopropylmalate dehydratase | 0.35 | RR42_RS18305 | | anthranilate phosphoribosyltransferase | low | > 128 |
| Paraburkholderia graminis OAS925 | 0.56 | ABIE53_004803 | | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit | 0.34 | ABIE53_003642 | | anthranilate phosphoribosyltransferase | — | — |
| Ralstonia solanacearum GMI1000 | 0.56 | RS_RS09995 | | 3-isopropylmalate dehydratase small subunit | 0.34 | RS_RS20385 | | Anthranilate phosphoribosyltransferase 2 | — | — |
| Ralstonia sp. UNC404CL21Col | 0.56 | ABZR87_RS14535 | | 3-isopropylmalate dehydratase small subunit | 0.32 | ABZR87_RS02155 | | anthranilate phosphoribosyltransferase | 0.86 | 13 |
| Kangiella aquimarina DSM 16071 | 0.56 | B158DRAFT_1320 | | 3-isopropylmalate dehydratase, small subunit | 0.46 | B158DRAFT_2427 | | anthranilate phosphoribosyltransferase | low | > 40 |
| Acinetobacter baumannii LAC-4 | 0.55 | RR41_RS16895 | | 3-isopropylmalate dehydratase small subunit | 0.33 | RR41_RS05610 | | anthranilate phosphoribosyltransferase | low | > 55 |
| Herbaspirillum seropedicae SmR1 | 0.55 | HSERO_RS16505 | | 3-isopropylmalate dehydratase small subunit | 0.28 | HSERO_RS19445 | | anthranilate phosphoribosyltransferase | 0.90 | 13 |
| Variovorax sp. OAS795 | 0.55 | ABID97_RS08460 | | 3-isopropylmalate dehydratase small subunit | 0.34 | ABID97_RS05275 | | anthranilate phosphoribosyltransferase | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.55 | GFF3361 | | 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) | 0.33 | GFF3110 | | Anthranilate phosphoribosyltransferase (EC 2.4.2.18) | 0.73 | 23 |
| Variovorax sp. SCN45 | 0.55 | GFF3889 | | 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) | 0.34 | GFF5891 | | Anthranilate phosphoribosyltransferase (EC 2.4.2.18) | — | — |
| Methylophilus sp. DMC18 | 0.55 | GFF647 | | 3-isopropylmalate dehydratase small subunit 1 | 0.30 | GFF2047 | | Anthranilate phosphoribosyltransferase | — | — |
| Castellaniella sp019104865 MT123 | 0.53 | ABCV34_RS04285 | | 3-isopropylmalate dehydratase small subunit | 0.27 | ABCV34_RS10305 | | anthranilate phosphoribosyltransferase | low | > 48 |
| Azospirillum sp. SherDot2 | 0.53 | MPMX19_00606 | | 3-isopropylmalate dehydratase small subunit 1 | 0.36 | MPMX19_01015 | | Anthranilate phosphoribosyltransferase | 0.80 | 22 |
| Dechlorosoma suillum PS | 0.53 | Dsui_3199 | | 3-isopropylmalate dehydratase, small subunit | 0.35 | Dsui_0169 | | anthranilate phosphoribosyltransferase | — | — |
| Azospirillum brasilense Sp245 | 0.52 | AZOBR_RS14135 | | isopropylmalate isomerase | 0.36 | AZOBR_RS07455 | | anthranilate phosphoribosyltransferase | 0.69 | 33 |
| Magnetospirillum magneticum AMB-1 | 0.52 | AMB_RS20565 | | 3-isopropylmalate dehydratase small subunit | 0.33 | AMB_RS14410 | | anthranilate phosphoribosyltransferase | — | — |
| Acidovorax sp. GW101-3H11 | 0.52 | Ac3H11_1527 | | 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) | 0.34 | Ac3H11_771 | | Anthranilate phosphoribosyltransferase (EC 2.4.2.18) | 0.90 | 12 |
| Dinoroseobacter shibae DFL-12 | 0.51 | Dshi_0083 | | 3-isopropylmalate dehydratase, small subunit (RefSeq) | 0.35 | Dshi_1799 | | anthranilate phosphoribosyltransferase (RefSeq) | — | — |
| Rhodopseudomonas palustris CGA009 | 0.51 | TX73_001215 | | 3-isopropylmalate dehydratase small subunit | 0.37 | TX73_014980 | | anthranilate phosphoribosyltransferase | — | — |
| Rhodospirillum rubrum S1H | 0.50 | Rru_A1190 | | 3-isopropylmalate dehydratase small subunit region (NCBI) | 0.33 | Rru_A1896 | | Anthranilate phosphoribosyl transferase (NCBI) | 0.76 | 10 |
| Phaeobacter inhibens DSM 17395 | 0.50 | PGA1_c29790 | | 3-isopropylmalate dehydratase small subunit | 0.36 | PGA1_c16890 | | anthranilate phosphoribosyltransferase TrpD | — | — |
| Bosea sp. OAE506 | 0.50 | ABIE41_RS11640 | | 3-isopropylmalate dehydratase small subunit | 0.33 | ABIE41_RS17420 | | anthranilate phosphoribosyltransferase | — | — |
| Sinorhizobium meliloti 1021 | 0.49 | SMc03795 | | isopropylmalate isomerase small subunit | 0.35 | SMc00235 | | anthranilate phosphoribosyltransferase | 0.74 | 70 |
| Agrobacterium fabrum C58 | 0.49 | Atu2790 | | 3-isopropylmalate dehydratase, small subunit | 0.32 | Atu1687 | | anthranilate phosphoribosyltransferase | 0.88 | 20 |
| Rhizobium sp. OAE497 | 0.49 | ABIE40_RS19040 | | 3-isopropylmalate dehydratase small subunit | 0.35 | ABIE40_RS09545 | | anthranilate phosphoribosyltransferase | low | > 107 |
| Xanthobacter sp. DMC5 | 0.47 | GFF1843 | | 3-isopropylmalate dehydratase small subunit 1 | 0.35 | GFF953 | | Anthranilate phosphoribosyltransferase | — | — |
| Caulobacter crescentus NA1000 | 0.43 | CCNA_00195 | | 3-isopropylmalate dehydratase small subunit | 0.36 | CCNA_01975 | | anthranilate phosphoribosyltransferase | 0.91 | 29 |
| Caulobacter crescentus NA1000 Δfur | 0.43 | CCNA_00195 | | 3-isopropylmalate dehydratase small subunit | 0.36 | CCNA_01975 | | anthranilate phosphoribosyltransferase | low | > 67 |
| Rhodanobacter denitrificans MT42 | 0.42 | LRK55_RS07100 | | 3-isopropylmalate dehydratase small subunit | 0.31 | LRK55_RS11295 | | anthranilate phosphoribosyltransferase | low | > 63 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.42 | ABZR88_RS11600 | | 3-isopropylmalate dehydratase small subunit | 0.28 | ABZR88_RS10675 | | anthranilate phosphoribosyltransferase | — | — |
| Rhodanobacter denitrificans FW104-10B01 | 0.42 | LRK54_RS07370 | | 3-isopropylmalate dehydratase small subunit | 0.31 | LRK54_RS11565 | | anthranilate phosphoribosyltransferase | 0.29 | 43 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.41 | CA264_09440 | | 3-isopropylmalate dehydratase small subunit | 0.26 | CA264_05065 | | anthranilate phosphoribosyltransferase | low | > 74 |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.41 | CA265_RS15840 | | 3-isopropylmalate dehydratase small subunit | 0.27 | CA265_RS05010 | | anthranilate phosphoribosyltransferase (EC 2.4.2.18) (from data) | 0.68 | 69 |
| Bifidobacterium breve UCC2003 | 0.40 | BBR_RS19625 | | 3-isopropylmalate dehydratase small subunit | 0.26 | BBR_RS16510 | | anthranilate phosphoribosyltransferase | low | > 34 |
| Bacteroides stercoris CC31F | 0.40 | HMPREF1181_RS14140 | | 3-isopropylmalate dehydratase small subunit | 0.27 | HMPREF1181_RS15335 | | anthranilate phosphoribosyltransferase | 0.77 | 50 |
| Parabacteroides merdae CL09T00C40 | 0.39 | HMPREF1078_RS16655 | | 3-isopropylmalate dehydratase small subunit | 0.27 | HMPREF1078_RS00135 | | anthranilate phosphoribosyltransferase | 0.82 | 28 |
| Bacteroides ovatus ATCC 8483 | 0.39 | BACOVA_04602 | | 3-isopropylmalate dehydratase, small subunit | 0.28 | BACOVA_03782 | | anthranilate phosphoribosyltransferase | low | > 96 |
| Sphingomonas koreensis DSMZ 15582 | 0.38 | Ga0059261_4225 | | 3-isopropylmalate dehydratase, small subunit | 0.24 | Ga0059261_0929 | | anthranilate phosphoribosyltransferase | 0.93 | 41 |
| Dyella japonica UNC79MFTsu3.2 | 0.38 | ABZR86_RS15955 | | 3-isopropylmalate dehydratase small subunit | 0.31 | ABZR86_RS12070 | | anthranilate phosphoribosyltransferase | low | > 74 |
| Phocaeicola vulgatus CL09T03C04 | 0.38 | HMPREF1058_RS14555 | | 3-isopropylmalate dehydratase small subunit | 0.26 | HMPREF1058_RS07185 | | anthranilate phosphoribosyltransferase | 0.85 | 12 |
| Phocaeicola dorei CL03T12C01 | 0.38 | ABI39_RS10205 | | 3-isopropylmalate dehydratase small subunit | 0.27 | ABI39_RS21060 | | anthranilate phosphoribosyltransferase | 0.73 | 45 |
| Sphingobium sp. HT1-2 | 0.38 | GFF2628 | | 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) | 0.24 | GFF3537 | | Anthranilate phosphoribosyltransferase (EC 2.4.2.18) | 0.83 | 20 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.38 | BT1859 | | 3-isopropylmalate dehydratase small subunit (NCBI ptt file) | 0.28 | BT0530 | | anthranilate phosphoribosyltransferase (EC 2.4.2.18) (from data) | 0.81 | 27 |
| Lysobacter sp. OAE881 | 0.37 | ABIE51_RS17580 | | 3-isopropylmalate dehydratase small subunit | 0.30 | ABIE51_RS04180 | | anthranilate phosphoribosyltransferase | low | > 62 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.36 | A4249_RS10000 | | 3-isopropylmalate dehydratase small subunit | 0.36 | A4249_RS06170 | | anthranilate phosphoribosyltransferase | — | — |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.36 | Echvi_2060 | | 3-isopropylmalate dehydratase, small subunit | 0.29 | Echvi_2507 | | anthranilate phosphoribosyltransferase | — | — |
| Cellulophaga baltica 18 | 0.36 | M666_RS15055 | | 3-isopropylmalate dehydratase small subunit | 0.28 | M666_RS09080 | | anthranilate phosphoribosyltransferase | low | > 67 |
| Synechocystis sp000284455 PCC 6803 | 0.30 | SGL_RS10800 | | 3-isopropylmalate dehydratase small subunit | 0.33 | SGL_RS07485 | | anthranilate phosphoribosyltransferase | — | — |
| Synechococcus elongatus PCC 7942 | 0.25 | Synpcc7942_2548 | leuD | isopropylmalate isomerase small subunit | 0.30 | Synpcc7942_2123 | trpD | anthranilate phosphoribosyltransferase | — | — |
Not shown: 23 genomes with orthologs for CSW01_12610 only; 4 genomes with orthologs for CSW01_05940 only